LOCUS       DAVHSH010000001       143081 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000001 DAVHSH010000000
VERSION     DAVHSH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 143081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 143081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..143081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.001"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VVR08_000001"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VVR08_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU6073991.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VVR08_000002"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VVR08_000002"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU6073992.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VVR08_000003"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VVR08_000003"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU6073993.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VVR08_000004"
     CDS             complement(3795..5063)
                     /locus_tag="VVR08_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU6073994.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VVR08_000005"
     CDS             complement(5183..5551)
                     /locus_tag="VVR08_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU6073995.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VVR08_000006"
     CDS             complement(5544..5810)
                     /locus_tag="VVR08_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU6073996.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VVR08_000007"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VVR08_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU6073997.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEMSQLEPCRIEFFGDEIDGIRSFEVETQLSKENKI
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELVLQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VVR08_000008"
     CDS             complement(9378..9947)
                     /locus_tag="VVR08_000008"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU6073998.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VVR08_000009"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VVR08_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU6073999.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKATQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VVR08_000010"
     CDS             complement(11217..11411)
                     /locus_tag="VVR08_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU6074000.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VVR08_000011"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VVR08_000011"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU6074001.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VVR08_000012"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VVR08_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU6074002.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VVR08_000013"
     CDS             complement(14345..15103)
                     /locus_tag="VVR08_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU6074003.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VVR08_000014"
     CDS             complement(15161..16342)
                     /locus_tag="VVR08_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU6074004.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VVR08_000015"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VVR08_000015"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU6074005.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VVR08_000016"
     tRNA            17048..17121
                     /locus_tag="VVR08_000016"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VVR08_000017"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VVR08_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU6074006.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VVR08_000018"
     CDS             17432..18757
                     /locus_tag="VVR08_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6074007.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VVR08_000019"
     CDS             18754..19506
                     /locus_tag="VVR08_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074008.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VVR08_000020"
     tRNA            19558..19629
                     /locus_tag="VVR08_000020"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VVR08_000021"
     tRNA            19635..19708
                     /locus_tag="VVR08_000021"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VVR08_000022"
     CDS             complement(19749..20291)
                     /locus_tag="VVR08_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU6074009.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..21237
                     /locus_tag="VVR08_000023"
     CDS             20470..21237
                     /locus_tag="VVR08_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU6074010.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21322..21660
                     /locus_tag="VVR08_000024"
     CDS             21322..21660
                     /locus_tag="VVR08_000024"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074011.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFFAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            21700..21972
                     /locus_tag="VVR08_000025"
     CDS             21700..21972
                     /locus_tag="VVR08_000025"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU6074012.1"
                     /translation="MVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATWNSRI
                     GAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLR"
     gene            complement(22103..24655)
                     /locus_tag="VVR08_000026"
     CDS             complement(22103..24655)
                     /locus_tag="VVR08_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU6074013.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24717..26339)
                     /locus_tag="VVR08_000027"
     CDS             complement(24717..26339)
                     /locus_tag="VVR08_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6074014.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26545..27570
                     /gene="trpS"
                     /locus_tag="VVR08_000028"
     CDS             26545..27570
                     /gene="trpS"
                     /locus_tag="VVR08_000028"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU6074015.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27722..29200
                     /gene="guaB"
                     /locus_tag="VVR08_000029"
     CDS             27722..29200
                     /gene="guaB"
                     /locus_tag="VVR08_000029"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU6074016.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VVR08_000030"
     CDS             complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VVR08_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU6074017.1"
                     /translation="MWLQHLSLKTFRNYTETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VVR08_000031"
     CDS             complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VVR08_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU6074018.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30878..32128
                     /locus_tag="VVR08_000032"
     CDS             30878..32128
                     /locus_tag="VVR08_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6074019.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIVKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32125..33408
                     /locus_tag="VVR08_000033"
     CDS             32125..33408
                     /locus_tag="VVR08_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6074020.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLIVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33450..34271
                     /locus_tag="VVR08_000034"
     CDS             33450..34271
                     /locus_tag="VVR08_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6074021.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34282..34827
                     /gene="pgsA"
                     /locus_tag="VVR08_000035"
     CDS             34282..34827
                     /gene="pgsA"
                     /locus_tag="VVR08_000035"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU6074022.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34824..35651
                     /locus_tag="VVR08_000036"
     CDS             34824..35651
                     /locus_tag="VVR08_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6074023.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVVLRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSHNGYNLPENYLTESELEDKLWELL"
     gene            35636..36475
                     /locus_tag="VVR08_000037"
     CDS             35636..36475
                     /locus_tag="VVR08_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6074024.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36468..37262
                     /locus_tag="VVR08_000038"
     CDS             36468..37262
                     /locus_tag="VVR08_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6074025.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKSMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37321..38139
                     /gene="mreC"
                     /locus_tag="VVR08_000039"
     CDS             37321..38139
                     /gene="mreC"
                     /locus_tag="VVR08_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU6074026.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38139..38633
                     /gene="mreD"
                     /locus_tag="VVR08_000040"
     CDS             38139..38633
                     /gene="mreD"
                     /locus_tag="VVR08_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU6074027.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38727..39905
                     /locus_tag="VVR08_000041"
     CDS             38727..39905
                     /locus_tag="VVR08_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6074028.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAVAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40129..40908
                     /gene="rpsB"
                     /locus_tag="VVR08_000042"
     CDS             40129..40908
                     /gene="rpsB"
                     /locus_tag="VVR08_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU6074029.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40987..42027
                     /locus_tag="VVR08_000043"
     CDS             40987..42027
                     /locus_tag="VVR08_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU6074030.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVITE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42273..42596
                     /gene="tnpB"
                     /locus_tag="VVR08_000044"
                     /pseudo
     CDS             42273..42596
                     /gene="tnpB"
                     /locus_tag="VVR08_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(42751..43038)
                     /locus_tag="VVR08_000045"
                     /pseudo
     CDS             complement(42751..43038)
                     /locus_tag="VVR08_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43029..43427
                     /locus_tag="VVR08_000046"
     CDS             43029..43427
                     /locus_tag="VVR08_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6074031.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLDPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43624..44544)
                     /gene="cysK"
                     /locus_tag="VVR08_000047"
     CDS             complement(43624..44544)
                     /gene="cysK"
                     /locus_tag="VVR08_000047"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU6074032.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDNALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44829..45464)
                     /locus_tag="VVR08_000048"
     CDS             complement(44829..45464)
                     /locus_tag="VVR08_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU6074033.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45520..46818
                     /locus_tag="VVR08_000049"
     CDS             45520..46818
                     /locus_tag="VVR08_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6074034.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46815..47477
                     /locus_tag="VVR08_000050"
     CDS             46815..47477
                     /locus_tag="VVR08_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU6074035.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47557..48105
                     /gene="raiA"
                     /locus_tag="VVR08_000051"
     CDS             47557..48105
                     /gene="raiA"
                     /locus_tag="VVR08_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU6074036.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48241..50214
                     /locus_tag="VVR08_000052"
     CDS             48241..50214
                     /locus_tag="VVR08_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU6074037.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50211..50663
                     /gene="rplI"
                     /locus_tag="VVR08_000053"
     CDS             50211..50663
                     /gene="rplI"
                     /locus_tag="VVR08_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU6074038.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50706..52058
                     /gene="dnaB"
                     /locus_tag="VVR08_000054"
     CDS             50706..52058
                     /gene="dnaB"
                     /locus_tag="VVR08_000054"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU6074039.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52060..52326
                     /locus_tag="VVR08_000055"
     CDS             52060..52326
                     /locus_tag="VVR08_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074040.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGNVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52415..53761
                     /gene="cbpD"
                     /locus_tag="VVR08_000056"
     CDS             52415..53761
                     /gene="cbpD"
                     /locus_tag="VVR08_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU6074041.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      53844..53946
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54018..54308
                     /locus_tag="VVR08_000057"
     CDS             54018..54308
                     /locus_tag="VVR08_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU6074042.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETPH"
     gene            54271..55029
                     /locus_tag="VVR08_000058"
     CDS             54271..55029
                     /locus_tag="VVR08_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074043.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55067..56074
                     /locus_tag="VVR08_000059"
     CDS             55067..56074
                     /locus_tag="VVR08_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6074044.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56074..56802
                     /locus_tag="VVR08_000060"
     CDS             56074..56802
                     /locus_tag="VVR08_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074045.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56921..57379
                     /locus_tag="VVR08_000061"
     CDS             56921..57379
                     /locus_tag="VVR08_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU6074046.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57381..59813
                     /locus_tag="VVR08_000062"
     CDS             57381..59813
                     /locus_tag="VVR08_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6074047.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60455..61108
                     /gene="rr06"
                     /locus_tag="VVR08_000063"
     CDS             60455..61108
                     /gene="rr06"
                     /locus_tag="VVR08_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU6074048.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61105..62436
                     /gene="hk06"
                     /locus_tag="VVR08_000064"
     CDS             61105..62436
                     /gene="hk06"
                     /locus_tag="VVR08_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU6074049.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESTRVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCVPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62519..63046
                     /locus_tag="VVR08_000065"
     CDS             62519..63046
                     /locus_tag="VVR08_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU6074050.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63125..65248
                     /gene="pspC"
                     /locus_tag="VVR08_000066"
     CDS             63125..65248
                     /gene="pspC"
                     /locus_tag="VVR08_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU6074051.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGN
                     NSTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSAIKTKYLY
                     ELSVLEEKSEAELTSKTKETKEELDAAFEQFKKDTLSTEPEKKVAEAQKKVAEAKKKA
                     EVQKEEDHRNYPTITYKTLELEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKV
                     ESEKAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEQATPDKKE
                     NDAKSSDSSVGEKTLPSPSLKPGKKVAEAEKKVEEADKKAKAQKEEDRRNYPTNTYKT
                     LELEIAESDVKVKEAELELVKEEAKEPQNEEKIKQAKAKVESKKAEATRLEKIKTDRK
                     KAEEEAKRKAAEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAEQPKAEKPADQQAEE
                     DYARRSEEEYNRLTQQQPPKTEKPAPAPQPEQPAPAPKTGWKQENGMWYFYNTDGSMA
                     TGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNSNGAMATGWLQYNDSWYYLNANGA
                     METGWLEYNGSWYYLNANGDMAIGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNSN
                     GAMVTGWLQNNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYV
                     NGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(65478..66458)
                     /gene="dusB"
                     /locus_tag="VVR08_000067"
     CDS             complement(65478..66458)
                     /gene="dusB"
                     /locus_tag="VVR08_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU6074052.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(66445..67317)
                     /gene="hslO"
                     /locus_tag="VVR08_000068"
     CDS             complement(66445..67317)
                     /gene="hslO"
                     /locus_tag="VVR08_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU6074053.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELICDKS"
     gene            67482..68909
                     /locus_tag="VVR08_000069"
     CDS             67482..68909
                     /locus_tag="VVR08_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6074054.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYNPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            69068..70576
                     /gene="glpK"
                     /locus_tag="VVR08_000070"
     CDS             69068..70576
                     /gene="glpK"
                     /locus_tag="VVR08_000070"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU6074055.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            70618..72444
                     /gene="glpO"
                     /locus_tag="VVR08_000071"
     CDS             70618..72444
                     /gene="glpO"
                     /locus_tag="VVR08_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU6074056.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            72514..73218
                     /locus_tag="VVR08_000072"
     CDS             72514..73218
                     /locus_tag="VVR08_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6074057.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLLWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            73515..73718
                     /locus_tag="VVR08_000073"
     CDS             73515..73718
                     /locus_tag="VVR08_000073"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074058.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(73805..74413)
                     /locus_tag="VVR08_000074"
     CDS             complement(73805..74413)
                     /locus_tag="VVR08_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074059.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            75560..76836
                     /gene="ltrA"
                     /locus_tag="VVR08_000075"
                     /pseudo
     CDS             75560..76836
                     /gene="ltrA"
                     /locus_tag="VVR08_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            77288..78466
                     /locus_tag="VVR08_000076"
     CDS             77288..78466
                     /locus_tag="VVR08_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6074060.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFLLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            78780..78911
                     /locus_tag="VVR08_000077"
     CDS             78780..78911
                     /locus_tag="VVR08_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU6074061.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            78932..80482
                     /gene="dltA"
                     /locus_tag="VVR08_000078"
     CDS             78932..80482
                     /gene="dltA"
                     /locus_tag="VVR08_000078"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU6074062.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDLQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            80479..81723
                     /gene="dltB"
                     /locus_tag="VVR08_000079"
     CDS             80479..81723
                     /gene="dltB"
                     /locus_tag="VVR08_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU6074063.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVVGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            81737..81976
                     /gene="dltC"
                     /locus_tag="VVR08_000080"
     CDS             81737..81976
                     /gene="dltC"
                     /locus_tag="VVR08_000080"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU6074064.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            81969..83237
                     /gene="dltD"
                     /locus_tag="VVR08_000081"
     CDS             81969..83237
                     /gene="dltD"
                     /locus_tag="VVR08_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU6074065.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            83392..83832
                     /gene="adcR"
                     /locus_tag="VVR08_000082"
     CDS             83392..83832
                     /gene="adcR"
                     /locus_tag="VVR08_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU6074066.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            83832..84536
                     /locus_tag="VVR08_000083"
     CDS             83832..84536
                     /locus_tag="VVR08_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6074067.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            84529..85335
                     /locus_tag="VVR08_000084"
     CDS             84529..85335
                     /locus_tag="VVR08_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6074068.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            85345..86850
                     /gene="adcA"
                     /locus_tag="VVR08_000085"
     CDS             85345..86850
                     /gene="adcA"
                     /locus_tag="VVR08_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU6074069.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(87977..88750)
                     /locus_tag="VVR08_000086"
     CDS             complement(87977..88750)
                     /locus_tag="VVR08_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6074070.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            88926..90329
                     /locus_tag="VVR08_000087"
     CDS             88926..90329
                     /locus_tag="VVR08_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU6074071.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLLSQGKINEDTELK
                     DIMTNIADTKYYYPQLS"
     gene            90359..91651
                     /locus_tag="VVR08_000088"
     CDS             90359..91651
                     /locus_tag="VVR08_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6074072.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLAAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWDDFTQAMASIRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVHTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            91738..92667
                     /locus_tag="VVR08_000089"
     CDS             91738..92667
                     /locus_tag="VVR08_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6074073.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            92670..93509
                     /locus_tag="VVR08_000090"
     CDS             92670..93509
                     /locus_tag="VVR08_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6074074.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            93506..94825
                     /locus_tag="VVR08_000091"
     CDS             93506..94825
                     /locus_tag="VVR08_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6074075.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            94831..96702
                     /locus_tag="VVR08_000092"
     CDS             94831..96702
                     /locus_tag="VVR08_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEU6074076.1"
                     /translation="MKIENKNVRRNFFWGEGRFYTTDIVNKRAGVMIKNVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            96724..98940
                     /locus_tag="VVR08_000093"
     CDS             96724..98940
                     /locus_tag="VVR08_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6074077.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEIYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYCSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            98951..101968
                     /locus_tag="VVR08_000094"
     CDS             98951..101968
                     /locus_tag="VVR08_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEU6074078.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKGKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGIVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGIYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSHIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            101983..102711
                     /locus_tag="VVR08_000095"
     CDS             101983..102711
                     /locus_tag="VVR08_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU6074079.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYRPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            102724..104490
                     /locus_tag="VVR08_000096"
     CDS             102724..104490
                     /locus_tag="VVR08_000096"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU6074080.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            104636..105787
                     /locus_tag="VVR08_000097"
     CDS             104636..105787
                     /locus_tag="VVR08_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU6074081.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            105932..106816
                     /locus_tag="VVR08_000098"
     CDS             105932..106816
                     /locus_tag="VVR08_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6074082.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            107215..107466
                     /locus_tag="VVR08_000099"
     CDS             107215..107466
                     /locus_tag="VVR08_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6074083.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            107454..107745
                     /locus_tag="VVR08_000100"
                     /pseudo
     CDS             107454..107745
                     /locus_tag="VVR08_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(107928..108055)
                     /locus_tag="VVR08_000101"
                     /pseudo
     CDS             complement(107928..108055)
                     /locus_tag="VVR08_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(108150..109481)
                     /locus_tag="VVR08_000102"
     CDS             complement(108150..109481)
                     /locus_tag="VVR08_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU6074084.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLVILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(109503..111014)
                     /locus_tag="VVR08_000103"
     CDS             complement(109503..111014)
                     /locus_tag="VVR08_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU6074085.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVIGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(111225..112172)
                     /gene="arcC"
                     /locus_tag="VVR08_000104"
     CDS             complement(111225..112172)
                     /gene="arcC"
                     /locus_tag="VVR08_000104"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU6074086.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVEADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(112337..113353)
                     /gene="argF"
                     /locus_tag="VVR08_000105"
     CDS             complement(112337..113353)
                     /gene="argF"
                     /locus_tag="VVR08_000105"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU6074087.1"
                     /translation="MTNLVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(113411..114640)
                     /gene="arcA"
                     /locus_tag="VVR08_000106"
     CDS             complement(113411..114640)
                     /gene="arcA"
                     /locus_tag="VVR08_000106"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU6074088.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            115395..117074
                     /locus_tag="VVR08_000107"
     CDS             115395..117074
                     /locus_tag="VVR08_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6074089.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWHEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(117114..119198)
                     /locus_tag="VVR08_000108"
     CDS             complement(117114..119198)
                     /locus_tag="VVR08_000108"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU6074090.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQASD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLEQKQGKTLSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSTCKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSTLGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            119369..120649
                     /locus_tag="VVR08_000109"
     CDS             119369..120649
                     /locus_tag="VVR08_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU6074091.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQITLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSPEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            120840..123485
                     /locus_tag="VVR08_000110"
     CDS             120840..123485
                     /locus_tag="VVR08_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU6074092.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQAECAKWGKSTQIGYFPDTFGNMGQAPQILQQSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGADGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVCTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRILVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            123569..124438
                     /locus_tag="VVR08_000111"
     CDS             123569..124438
                     /locus_tag="VVR08_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6074093.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLASAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAATGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            124432..126312
                     /locus_tag="VVR08_000112"
     CDS             124432..126312
                     /locus_tag="VVR08_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6074094.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRIQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(126734..126883)
                     /gene="rpmG"
                     /locus_tag="VVR08_000113"
     CDS             complement(126734..126883)
                     /gene="rpmG"
                     /locus_tag="VVR08_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6074095.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(126899..127081)
                     /gene="rpmF"
                     /locus_tag="VVR08_000114"
     CDS             complement(126899..127081)
                     /gene="rpmF"
                     /locus_tag="VVR08_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU6074096.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(127233..127433)
                     /locus_tag="VVR08_000115"
     CDS             complement(127233..127433)
                     /locus_tag="VVR08_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6074097.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(127436..128443)
                     /locus_tag="VVR08_000116"
     CDS             complement(127436..128443)
                     /locus_tag="VVR08_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6074098.1"
                     /translation="MTEKLINSKPNGVFALILIELTIILGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            128634..130664
                     /locus_tag="VVR08_000117"
     CDS             128634..130664
                     /locus_tag="VVR08_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU6074099.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            130668..130952
                     /locus_tag="VVR08_000118"
     CDS             130668..130952
                     /locus_tag="VVR08_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6074100.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            130965..132169
                     /locus_tag="VVR08_000119"
                     /pseudo
     CDS             130965..132169
                     /locus_tag="VVR08_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            132173..133030
                     /locus_tag="VVR08_000120"
     CDS             132173..133030
                     /locus_tag="VVR08_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6074101.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            133027..133959
                     /locus_tag="VVR08_000121"
     CDS             133027..133959
                     /locus_tag="VVR08_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU6074102.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVVDELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            134192..135895
                     /gene="ilvD"
                     /locus_tag="VVR08_000122"
     CDS             134192..135895
                     /gene="ilvD"
                     /locus_tag="VVR08_000122"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU6074103.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(136056..136136)
                     /locus_tag="VVR08_000123"
                     /pseudo
     CDS             complement(136056..136136)
                     /locus_tag="VVR08_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(136194..136535)
                     /locus_tag="VVR08_000124"
     CDS             complement(136194..136535)
                     /locus_tag="VVR08_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6074104.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            136659..137510
                     /gene="rgg"
                     /locus_tag="VVR08_000125"
     CDS             136659..137510
                     /gene="rgg"
                     /locus_tag="VVR08_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU6074105.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYKLNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            137700..138947
                     /locus_tag="VVR08_000126"
     CDS             137700..138947
                     /locus_tag="VVR08_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU6074106.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLPQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDRFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            139025..140314
                     /locus_tag="VVR08_000127"
     CDS             139025..140314
                     /locus_tag="VVR08_000127"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU6074107.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            140610..140924
                     /locus_tag="VVR08_000128"
     CDS             140610..140924
                     /locus_tag="VVR08_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074108.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            140934..141140
                     /locus_tag="VVR08_000129"
     CDS             140934..141140
                     /locus_tag="VVR08_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6074109.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            141140..141337
                     /locus_tag="VVR08_000130"
     CDS             141140..141337
                     /locus_tag="VVR08_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074110.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            141340..142074
                     /locus_tag="VVR08_000131"
     CDS             141340..142074
                     /locus_tag="VVR08_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU6074111.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            142086..142727
                     /locus_tag="VVR08_000132"
     CDS             142086..142727
                     /locus_tag="VVR08_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6074112.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            142745..142975
                     /locus_tag="VVR08_000133"
     CDS             142745..142975
                     /locus_tag="VVR08_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074113.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT        43999 a        25081 c        29825 g        44176 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga gtttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaagca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 tgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacggccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 cttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgttccttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctctttct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat taattcacct tctaatggaa gtccaaaaga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctt
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaattttcca catcaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccga tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagttctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gccagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atagaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatcttgt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctag cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacattttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataggagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttatcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatac tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aattccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt gctaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt agcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtttccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccccccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacatgc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 agtcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaaccaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctcc
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tgtcaacttt gttgtaaaga
     6901 tagtaaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gacaaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caacattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt cggtccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttga tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggga tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcgcgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagctcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccctctat taagtttaca gattctttac agatacttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact ttgcttttga
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctatctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gacatttcaa aaatatctaa aatatctcct cgaagactaa attcgccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgatcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga gataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatataa
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgagtagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttctgaa accacatcct cgtccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccgtct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaattaatt ccagattaat
    10741 tgtatcaata tctgcaagtg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cttctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 cgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 taggcgttca tctggaactt ccaccattcc aacatttgga tcaatagtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag ttgacttgat tgtacaagcg tgtgattttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatta acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgaaatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt catatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcaa ctttttttcc gctgagtgac tgaatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagttataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgatgagt
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa tcaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaactacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat cttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttctcca ggtactttag tcccatctga caatctaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaactgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattagat ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 cgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacctataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcagtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctaa aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gggataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaaggttt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca agctaatcaa gtattaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagctgtta ctagcaaatt agttcctgcc
    21061 agtcagttga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt
    21181 tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta
    21241 caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca
    21301 ttagagaata gagctaataa attggcagat ggatctggga aactagcaga aggtggaaca
    21361 aagttaactt ctggattgga agatttacag acaggacttg cttctttagg acaaggacta
    21421 ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg
    21481 tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca
    21541 atagctcctt atatgatatc agttgctctt ttttttgcag caatatcaac aaatatgata
    21601 tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt gaaatcttga
    21661 gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcag
    21721 cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat cctaacaagt
    21781 ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat aggagctttt
    21841 ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta tccacttgct
    21901 ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta ttcagtttcg
    21961 ggattacgat aaacaatctc tatcaacaag tcattttcct agctgtcata ctagctctat
    22021 ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat taaaaaaatc
    22081 gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga ttatagattc
    22141 caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca ttgggaatga
    22201 aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat ccagtttgag
    22261 cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg tcataaggaa
    22321 tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc ttgtttttag
    22381 aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg aaagttttgg
    22441 tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca gggaaactaa
    22501 cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag gagaagacat
    22561 tatcagttgt aaaagtcttt ttttcaccat ttacaagtat gtcaaccttc ttttgtttat
    22621 cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct ggaacttcaa
    22681 tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc aaatcattag
    22741 tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca aaattgacgt
    22801 tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg aacttgacat
    22861 cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt tcatataggg
    22921 taagattatc tttttgatag atatctttaa agccatactt atcaatagga ctgtctgaga
    22981 tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca tatcggagat
    23041 tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt gatgaacgat
    23101 ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg tcatttcctg
    23161 tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt gagaaagatt
    23221 ccatagctgg gatatctcga ctataagcac ttcgagaagc aaatccccat tccttagcaa
    23281 ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat aaagagatta
    23341 gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt aaaagagaat
    23401 agacaaccaa aaattcaaga gtaagcagaa tattcaaatc tgttaaaaaa gaataatgcg
    23461 attttagata gatggtagct aaaaatcctg ctactacaag aaaaagcgaa actaaaaaat
    23521 tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa attaacaagg
    23581 tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg ccttgccaaa
    23641 ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat attacatata
    23701 tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc aaaataaagg
    23761 gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca aaggaaccaa
    23821 tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac tttgtaactt
    23881 cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc ataatcaaac
    23941 tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat tttcgagtct
    24001 taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact gtcatatatc
    24061 caaaataata attttgaata aataagattg acagacttgt aaagtacaat aggagtttct
    24121 tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata aaaacatcta
    24181 gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag gaagtagata
    24241 aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta aaaaaggttg
    24301 acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct ggcatattcg
    24361 ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa ctagataggg
    24421 catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta tttccatgta
    24481 ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct cctaatagag
    24541 gagagttgtc gctattccag tagatacctt gagatagata tactccagac ataatcacta
    24601 caggaatgat gaaagaaata aaataggttc gatatgtttt taaaaatgat ttcatgttac
    24661 ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag ttttatttag
    24721 tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa ttcatcgtag
    24781 gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg gttagccaaa
    24841 gtttgaataa attcgtggtc atggctagca aagatgattg attctttaaa gtttttcaat
    24901 ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc atcaagtaca
    24961 aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt ttctccccct
    25021 gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg gccgaggaag
    25081 ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa ccagtcaaga
    25141 attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga ttgactagtt
    25201 gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc acgaattaat
    25261 gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg acgcaagatg
    25321 aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt ttctactgtc
    25381 aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata tttacgacta
    25441 gatggcacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga tgttgcctgc
    25501 cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg tttaattttt
    25561 tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga agattccttc
    25621 cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc ggccatgtga
    25681 gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt gttatcaaag
    25741 tcaattaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt agtaggctcg
    25801 tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac ctttactttt
    25861 tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat gtttaggttt
    25921 tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc aaactctcct
    25981 tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat gtagatagca
    26041 tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac atcaatggca
    26101 cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc atctggacca
    26161 agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa aaaggttgat
    26221 tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa tttgatattg
    26281 acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac tgtaagcaat
    26341 atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa tattcaaatt
    26401 tttatttgtc aattttgtgt aaattatatt tacagtatcc tttacacaaa tctgtaaaaa
    26461 gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc tataattgaa
    26521 aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg agaccgtcca
    26581 acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt attattacag
    26641 gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt gacagatcat
    26701 gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga ttatcttgca
    26761 gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc agagttggct
    26821 gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg aaatccaaca
    26881 gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg attcttggtc
    26941 tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt tcctgttggg
    27001 acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt taacaatgca
    27061 tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga gagagcaggg
    27121 cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa tggtatttat
    27181 ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac agatccagat
    27241 catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca ttatctagat
    27301 gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg ttatcaacga
    27361 ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga acgtgaactg
    27421 ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt ttataatatg
    27481 attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc tgaggtaaaa
    27541 ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta tcatttctat
    27601 ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt gtatagaatg
    27661 gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga ggaaacttcg
    27721 aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg atgtattgct
    27781 tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta aattggcaga
    27841 taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta cagagagtca
    27901 aatggccatt gctattgctc gtgcaggtgg tctcggagtt atccataaaa acatgtcaat
    27961 tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag ttattattga
    28021 tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta tgggtcgtta
    28081 ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg ttggtatttt
    28141 gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa accatatgac
    28201 tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg agagtattct
    28261 tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc tttctggttt
    28321 gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta aagatgagtt
    28381 tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg aacgtgcaga
    28441 ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg gtcattctgc
    28501 aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga ctttgattgc
    28561 tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg tagacgttgt
    28621 taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg gtgttggtgt
    28681 tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg gtaaaacgat
    28741 tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg ctgcaggtgg
    28801 aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag gcgaaactga
    28861 aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg ctgctatgaa
    28921 gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca agcttgttcc
    28981 agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg ttttccaaat
    29041 gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta aagaactaca
    29101 cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc atcctcatga
    29161 tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga aaagaactcc
    29221 agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagcag ctttaccatc
    29281 ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta agcttgttgt
    29341 tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact gtctagtgtt
    29401 gtcaagttca ctcatcacat cgtcaagcag taatatcgga gattctgtgg taatgctttc
    29461 cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt gaccttggct
    29521 tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat gaggaccgac
    29581 accagtattc tttttaaata aatctctgga tttacttttt tctaaagcaa ttttgaaaga
    29641 ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata ttgacaactc
    29701 ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta gtttttttat
    29761 gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat catctaacac
    29821 agaaaggaat gtttcatcta ttttttgatc tgattttagg taagtgtttc tttgctttag
    29881 gatgtggtta taattggtta agtcagataa gtagattggc ttaatttgcc caagttccat
    29941 atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat cttcaggagc
    30001 aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt ttaagtgatt
    30061 aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg atccagtttt
    30121 tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga gatttttatc
    30181 tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta acatgtttgt
    30241 ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt ctattttcgt
    30301 ttctgtgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga ttatctacca
    30361 gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt gtctttttta
    30421 actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac tttatcagct
    30481 tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat gttcatgtca
    30541 gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc taattcccta
    30601 ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct atgtgtaatt
    30661 ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt gtattccata
    30721 attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga gagacagaga
    30781 gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa taagaaaatt tcaggttttc
    30841 gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc atggaatttc
    30901 aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc gttttaccgc
    30961 tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc tagagactgc
    31021 taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc tatacggtac
    31081 agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat tgacatttac
    31141 ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga ttttggaact
    31201 tgtaaaagaa actctttttt cacccgtagt agttgataat gggtttgatc cggccttatt
    31261 tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg attcttttta
    31321 ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc aattggaata
    31381 tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt cttgtttcca
    31441 agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta atgaggttga
    31501 aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg tgaaggttca
    31561 gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa atgtgggaca
    31621 atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc aacatttacc
    31681 catgattgta atgaatggtt tacttggtgg atttgctcat tctaagctct ttacaaatgt
    31741 ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat ttagtggatt
    31801 cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta aaatgatgaa
    31861 taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa atcagaccaa
    31921 ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat tgattgaacg
    31981 tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt ggattgtaaa
    32041 gcttgaacag attgacaaag atgctatttg tagagtagct aataatgtga aactacaagc
    32101 gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa atactatcca
    32161 gctgtaaaag aaaaggttta tcgaactcgt ttggccaatg gattgatagt tgctcttttg
    32221 cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg ttcggtagat
    32281 acgtttgtca cagaagttga cggagatgta aaacaatatc ctggaggaat tgctcatttt
    32341 cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc ttttacgagt
    32401 ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct tttttcagca
    32461 acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc agcacacttt
    32521 actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga aatgtaccaa
    32581 gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc tggtacacct
    32641 ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct aactaatttg
    32701 caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt agttggtaat
    32761 tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga ttcagatttt
    32821 caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga tagtatgaga
    32881 atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga agtttctgaa
    32941 gcggattgct atcgacatca tattttatta aagttattgt ttgcaatgat gtttggttgg
    33001 acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcatc cttatctctg
    33061 gaagttgaag taacaagtcg ctttcatttt gtcatgttga caatggatac gaaagagcca
    33121 gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga tttagatatt
    33181 acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt cagtagcatg
    33241 aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga gacaattttt
    33301 gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc tggacatcat
    33361 ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta acctattata
    33421 atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga gaggttttac
    33481 gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag acagaaatcc
    33541 agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca agtccttttt
    33601 acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac caaattgttt
    33661 tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt gatgaagatg
    33721 agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca tttttacctt
    33781 tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat tatgtttgga
    33841 actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg gttcaatcaa
    33901 caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt atagaatcag
    33961 ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca agtaaggaaa
    34021 cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt tcagaaagcg
    34081 aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca acagttgcaa
    34141 ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg acagtagata
    34201 atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact gtaaccttta
    34261 ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt aacaataggt
    34321 cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc gatagagagt
    34381 catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt agatggatat
    34441 ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc tatggcggat
    34501 aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc tccggcttgg
    34561 attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct tttattggtt
    34621 gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac ttttagtcag
    34681 atgtttgcca ttattttctt gctattacat tggactttgc ttggtcaagt tctactttat
    34741 gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag tgcctatgta
    34801 tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat ctttcttttc
    34861 gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac gtgaaacgtg
    34921 gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg gttcgattaa
    34981 ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa cgtttgactg
    35041 aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat ccagacaatc
    35101 aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat cagggacttt
    35161 ctcgtcaaga aatgaaaaag agagtagaag aagctctggc tttagttggc atgttggact
    35221 ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg gccattgcag
    35281 gtgttgtagt cctaagacca gctattttaa tcttagatga agcaacgagt atgttggatc
    35341 ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac tatgatatga
    35401 cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc gtattggtca
    35461 tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct cgaaatgatt
    35521 tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct ttgagccata
    35581 atggctataa tttacctgaa aattatttga cagaaagtga gctagaggat aagctatggg
    35641 aattgctcta gaaaatgtga attttacata tcaagaaggt actcccttag cttcagcagc
    35701 tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa ttgggcacac
    35761 aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc caagtcaagg
    35821 gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag atattcgtca
    35881 aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt ttgaagaaac
    35941 ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag aagatgctgt
    36001 gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt ttgatcgtag
    36061 tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca tacttgccat
    36121 ggagccagct atattagtct tagatgagcc aacagctggt ctagatcctc tagggagaaa
    36181 ggagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg tcttggtaac
    36241 gcatttgatg gatgatgttg ctgaatatgc gaatcaagtc tatgtaatgg aaaagggacg
    36301 tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta tggaagaagt
    36361 tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata gaggcgtgtc
    36421 atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg gatagtatga
    36481 ttttagggcg ttatatccca ggggattcga ttgttcaccg attggatcca cgtagcaaat
    36541 tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc ttgacgaatc
    36601 tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct ctttcatttt
    36661 ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt tttcaactat
    36721 ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc acggattatg
    36781 ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc ttttcaactt
    36841 tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct ttattagcac
    36901 ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct atgagtttgc
    36961 gttttgtccc aaccttgatg gatgatacga cgcggattat gaatgcacag aaagctcgtg
    37021 gagtggattt tggagaagga agcatcgttc aaaaagtaaa gtcgatgatt cccattttga
    37081 ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct atggaagcgc
    37141 gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg actctaaagg
    37201 atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc ttaaaatctt
    37261 agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa aggtagggat
    37321 atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt tctgcttgtg
    37381 tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg agatggaatc
    37441 tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt caaatcagat
    37501 ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca gctttaccaa
    37561 ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca actgcgccaa
    37621 ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga tgttattatg
    37681 cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc aaaaggtgct
    37741 tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc aaaagtagag
    37801 gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa gatttctgtt
    37861 aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga caaggaaaat
    37921 gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg agataaggtg
    37981 actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga agtggttgcc
    38041 acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag tgcagatact
    38101 cataatgtag atgtgataga attagtgggg aattcataat gagacagttg aagcgagttg
    38161 gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc cagcttctgg
    38221 gctcattttt cccccatgta catttggcta gtcattttct ttttctattt ctcttatttg
    38281 agacgataga agtatcagag tatctctacc tagtctattg ttttgttata ggcttggttt
    38341 atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc ttattgggag
    38401 ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga atgctagcta
    38461 tgattgtgct gacattccta tttgaaatgg gtagttatct tttggctttt atggtagggt
    38521 tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg atgattttaa
    38581 attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta taagaacgac
    38641 atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac tagtattgtc
    38701 tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca cttttattaa
    38761 gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa acgactgatg
    38821 acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa caagaagccc
    38881 aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag cagtctaact
    38941 tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt gagattacag
    39001 aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct cgtagtgctc
    39061 aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa tcaattacag
    39121 aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac aaaatgttag
    39181 aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat aatgatgcta
    39241 tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca ttgactacga
    39301 aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg acagctgaag
    39361 gggaaaaagc aagtctatta gagcaaaaag cagtagctga ggcagaggct cgtgcagctg
    39421 cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca gtacttgctt
    39481 cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca gcagcacctg
    39541 tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca attggagaat
    39601 gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt aatggagcac
    39661 agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct caagttggag
    39721 caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca gctgttgaat
    39781 caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca attggaaatc
    39841 accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat atttatgcag
    39901 attaatttac agagggactc gaatagagcc ctcttttcag gttttagcgt gacaatccct
    39961 attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaaa atgaaaattg
    40021 tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct tgggtcgttt
    40081 tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat ggcagtaatt
    40141 tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg tcgctggaat
    40201 cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat cgacttgcaa
    40261 caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc agctaacgat
    40321 gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc tgaagaagca
    40381 gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct tacaaactgg
    40441 ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga agaagatgga
    40501 actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg tgcgcgtctt
    40561 gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat gtacgtagtt
    40621 gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat cccagttgta
    40681 gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc agctaacgat
    40741 gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat tatcgaagga
    40801 cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga aactcaagca
    40861 gattcaattg aagaaatcgt tgaagttgta gaaggcgaca acgcttaatt tatacaaata
    40921 gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa atataggaga
    40981 attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa atctggtgcc
    41041 ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga aaaagcgatt
    41101 gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aggctgaccg tgttgctgca
    41161 gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga agtaaacgct
    41221 gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac tacagctaaa
    41281 gtcattactg aaggaaaacc tgctaacaat gaagaagctc ttgctttgat aatgccttca
    41341 ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga gaaaatctca
    41401 ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc ataccaacat
    41461 aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc acttgctaaa
    41521 caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa agaattggat
    41581 gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca agacaacgaa
    41641 agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc aaaagctcaa
    41701 ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt ggctgcagaa
    41761 ggcaaaccag aaaaaatctg ggacaaaatt attccaggta aaatggatcg cttcatgctt
    41821 gataacacta aagttgacca agcttacaca cttcttgcac aagtttacat catggatgac
    41881 agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga gtttgctcgc
    41941 tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga agttgcagct
    42001 acaatggcag cagccttgaa taactaataa tagaaaggaa gcaatttgct tccttttttg
    42061 tatagggctt agatttttcc tgaaattgtt ttttccccag tctcactcga ttagaataat
    42121 taaaacaaaa agccctataa taagggctaa gtgcatttag gagagtatac ttcaaattca
    42181 tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt atactagata
    42241 aaaaataatt atcggaggaa aggtattgta ctatgataat tcaactaagt gatttaggtc
    42301 aagttcacct tgtttgtggc aagacagata tgaggtaggg aatagactca ttagcctatg
    42361 tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc ttttgtggtg
    42421 aacgtaaaga ccgctttaaa gccctttact gggatggtca aggattttgg ctactatata
    42481 aacgctttga gaacggaaaa ctgacttggt ccagtacaga aaaggatgtc aaagctctcg
    42541 cacctgaaca agtagattgg ctgatgaagg gcttttctat cactccaaaa atatagtaga
    42601 ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga tttgactgtc
    42661 ctgaacgatt tgtcctgttc ttatttcatt ttactataaa tccatcagaa agttgtgatt
    42721 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtcca
    42781 tctccgatta acgatggact ttatcacctc cttctccagt ccttgtatga catcttccaa
    42841 agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
    42901 ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag tcggaatctt
    42961 taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaagat aatcatctgg
    43021 ataagcttgt gaaagctcct attcctaaag cccctttggc gcatagcttt ggatcggctt
    43081 ctattatcgc tcacaccatc catcagaagt ttaatctgaa ggtacccaat tatcgccaag
    43141 aagaagattg ggctaagatg ggtttaccaa tcacacgcaa ggaaatctct aattggcata
    43201 tcaagacgag tcaatactat ttggaccctc tctataacct cttgcgagag agactattga
    43261 ctcagccctt acttcatgcg gatgaaactt cttatagggt gctagagagt gatagtcagc
    43321 tgacttacta ttggactttt ttgtctggga aagctgagaa acaagggatt acgctttacc
    43381 atcatgtcct aatcgatttg ttcatatctt atttcaatcc attataaata gcgagaaata
    43441 tctatcctat cttctagaat gtcttccaaa cgaggaaact ctcgtaaaca aagaggtttt
    43501 agaggcttat ttaccatgga ctaaagttgt accagaaaag tgcaaataag aaatctccag
    43561 attaggaact atccgtgagt tctctagtct ggagattttt taatatactt cgttattgga
    43621 cggttacaat tcataaagtg ctgtagagag ataacgttca ccgttatctg gtgctagggc
    43681 aaggactttt ttacctgtac ctaatttttt ggcaacctcg atggctccgt agatagctgc
    43741 agctgaggaa atccctacaa ggaagccttc ttttccacca atttcacgtc cgagtgcaag
    43801 agcgttatct gatgttacac gaacgatacc atcataggct ttagtatcaa gtgtatcagg
    43861 aataaatcca gctgagatac cttgaatttt gtgaggaccg ggtttttcac cagatagaat
    43921 agcagattca tctgcttcta ctgcaaaaac ttgaatgtta gaattttctg atttgagtgc
    43981 atgagaaaca ccagaaatcg ttccaccggt acctactcca gcaacaaagg catctaatcc
    44041 atctttaccg aaagcagcta gtatctcagc tcctgttgtt ctttcgtgta cttctggatt
    44101 agctggattg tcaaattgaa gaggaaggaa accatcacgt tcagcagcga tttcttgagc
    44161 cttagcaata gcacctttca ttccctcgct accaggagtt aggacgagtt cagcaccata
    44221 agcttggata attttacgtc gttctacact catagtttca ggcataacga tgacgacttt
    44281 atacccttta gcagcaccta cccatgaaag tccaatacca gtgtttccac ttgttgcttc
    44341 aacaatagta gaaccaggtt tcagaatacc atcttgttca gctttttcaa tcatgctaag
    44401 ggcaatacgg tcttttacag atgaaccagg attaaatgct tcaagcttta tatagacgtc
    44461 tgcagcacct tctggcacga tgttgttaag tttaacaatc ggtgtttgac cgattaattc
    44521 agtaatgttg ttataaatag acatatgaat acctctttgt ataagatatc tttagtataa
    44581 cgctatccat accatttgta aaatatagaa atcctatcga agcgatagga tttctatata
    44641 tcatagatca aagtcattaa ttttcaagtg attgcgttca gctaattcta gtaaataggt
    44701 gtgaaggaaa acgatatcag gtttcgtttg aattgcttca ttttctagta tattttggta
    44761 cgcatctttt tattttgctc gctaaagtag ttgtgagaat gtcaacgaaa cgctgtatta
    44821 ttcattgttt acactaagtt tacaggaact tcaacctctc gtaaaccttg gtcagttaaa
    44881 gtgacttttc cattaaaaaa ctccacaagt gcagctttaa tagtttcttt ttcttcttta
    44941 tcaacataaa tcatcgtatc gacttgatct gtaaagtttg tatccagctc catgagatca
    45001 tgttctttaa ggaagttact gtactcttgg tactgagcat aagacatttg aatagcaatg
    45061 ccagcctgtt cttttatttc aataatacca atttctttga cagctaaggc gacactgccg
    45121 gcgtaagcac gaattagtcc tccagcgcct agtttaatac caccaaagta gcgtgtcacg
    45181 accacacaga cattggtgag attgtgattt tctagtaccc caagcatggg aacaccagca
    45241 gtaccactag gctcaccatc atcacttgta cgtttaattt cactacgttc tccaataata
    45301 aaggcagagc agttatgtgt cgctttgtag tgttcttttt tgatggcagt aatgaagtca
    45361 cgagcctctt cttcgctata aacacgcttg gcatggcaga taaagcgaga ttttttgatt
    45421 tcttcttgga cttggccgtc ctctttaatt gtcctaaatt ccatgattta attgtactaa
    45481 aaaataatct aaagtgctag tttttacgaa taaagaagta tgaaagtaaa tttagattat
    45541 ctcggtcgtt tatttactga gaatgaatta acagaagaag aacgtcagtt ggcggagaaa
    45601 cttccagcaa tgagaaagga gaaggggaaa cttttctgtc aacgctgtaa tagtactatt
    45661 ctagaagaat ggtatttgcc catcggtgct tactattgtc gagagtgctt gctgatgaag
    45721 cgagtcagaa gtgatcaaac tttatactat tttccgcagg aggattttcc gaagcaagat
    45781 gttctcaaat ggcgcggcca attaactcct tttcaagaga aggtgtcaga gggattgctt
    45841 caagcagtag acaagcaaaa gccaacctta gttcatgcgg taacaggagc tggaaagaca
    45901 gaaatgattt atcaagtagt ggctaaagtg atcaatgcgg gtggtgcagt gtgtttggct
    45961 agtcctcgca tagatgtttg tttggagctg tacaagcgcc tgcaacagga tttttcttgc
    46021 ggtatagctt tgctacatgg agaatcggaa ccttattttc gaacaccact agttgttgca
    46081 acaacccatc agttattgaa gttttatcaa gcttttgatt tgctgatagt ggatgaagta
    46141 gatgcttttc cttatgttga taatcccacg ctttaccacg ctgtcaagaa tagtgtaaag
    46201 gagaatggat tgagaatctt tttaacagcg acttcgacca atgagttaga taaaaaggtc
    46261 cgtttaggag aactaaaaag actgagttta ccgagacggt ttcatggaaa tccgttgatt
    46321 attccaaaac caatttggtt atcggatttt aatcgctact tagacaagaa tcgtttgtca
    46381 ccaaagttaa agtcctatat tgagaagcag agaaagacag cttatccgtt actcattttt
    46441 gcttcagaaa ttaagaaagg ggagcagtta gaagaaatct tacaggagca atttccaaat
    46501 gagaaaattg gctttgtatc ttctgtaaca gaggatcgat tagagcaagt acaagctttt
    46561 cgagatggag aactgacaat acttatcagt acgacaatct tggagcgtgg agttaccttc
    46621 ccttgtgtgg atgttttcgt agtagaggcc aatcatcgtt tgtttaccaa gtctagtttg
    46681 attcagattg gtggacgagt tggacgaagc atggatagac cgacaggaga tttgcttttc
    46741 ttccatgatg ggttaaatgc ttcaatcaag aaggcgatta aggaaattca gatgatgaat
    46801 aaggaggctg gtctatgaag tgcttgttat gtgggcagac tatgaagact gttttaactt
    46861 ttagtagtct cttacttctg aggaataatg actcttgtct ttgttcagac tgtgattcta
    46921 cttttgaaag aattggggaa gagaactgtc caaattgtat gaaaacagag ttgtcaacaa
    46981 agtgtcaaga ttgtcaactt tggtgtaaag aaggagttga agtcagtcat agagcgattt
    47041 ttacttacaa tcaagctatg aaggattttt tcagtcggta taagtttgat ggagacttcc
    47101 tgttaagaaa agttttcgct tcatttttaa gtgaggagtt gaaaaagtac aaagagtatc
    47161 aatttgttgt aattccccta agtcctgata gatatgctaa tagaggattt aatcaggttg
    47221 agggcttggt agaggcagca ggctttgagt atctggattt attagagaaa agagaagaga
    47281 gagccagttc ttctaaaaat cgttcagagc gcttggggac agaacttcct ttctttatta
    47341 aaagtggagt cactattcct aaaaaaatcc tacttataga tgatatctat actacaggag
    47401 caactataaa tcgtgttaag aaactgttgg aagaagctgg tgctaaggat gtaaaaacat
    47461 tttcccttgt aagatgagga aaaaatttgc aaaaatagaa tgaaagcgtt ataataaaat
    47521 cataaaaaca aaaatgttta gaaagaaggt actcatatga ttaaatatag tatccgtggt
    47581 gaaaacctag aagtaacaga agcaattcgt gattatgtag tttctaaact cgaaaagatc
    47641 gaaaagtact tccaaccaga acaagagttg gatgcccgaa ttaacttaaa agtttatcgt
    47701 gaaaaaacgg ctaaagtgga agtaacgatt ccgcttggat ctattactct ccgcgcagaa
    47761 gatgtatctc aagatatgta tggttcaatt gaccttgtaa ctgataaaat tgaacgtcag
    47821 attcgtaaaa ataaaacaaa aatcgagcgt aaaaataaaa ataaggtagc aactggtcaa
    47881 ttatttacag atgctttggt ggaagattca aatattgtcc agtctaaagt tgttcgttca
    47941 aaacaaattg atttaaaacc aatggatttg gaagaagcaa ttctacaaat ggatttattg
    48001 gggcatgatt tctttatcta tgtggatgtt gaagatcaga caaccaatgt gatttatcgt
    48061 cgtgaggatg gcgaaattgg tttgttagag gttaaagaat cttaatttca atatgtgtaa
    48121 aggtaggttt actgaattgt aaactacctt tttcttataa ttgatagaat tactgattac
    48181 acttttaaaa agtcgctttt tgaggggtat tatggtataa tgggtgccaa gaggttttga
    48241 atgaaaaaat tttatgtaag tccaattttt cctattctag taggattgat tgcgtttgga
    48301 gtcttatcca ctttcattat ttttgttaat aataatctgt tgacggtttt aattttgttt
    48361 ctttttgtag gaggctatgt ttttttattt aagaaactga gagtgcatta tacaaggagt
    48421 gatgtagaac agatacagta tgtaaaccac caagcggaag aaagtttgac agctctattg
    48481 gaacagatgc ctgtaggtgt tatgaaattg aatttatctt ctggagaggt tgagtggttt
    48541 aatccctatg ctgaattgat tttgaccaag gaagatggtg attttgattt agaagctgtt
    48601 caaacgatta tcaaggcttc agtaggaaat ccgtctactt atgccaagct tggtgagaag
    48661 cgttatgctg ttcatatgga tgcttcttcc ggtgttttgt attttgtaga tgtatccagg
    48721 gaacaagcca taacagatga attggtaaca agtcgaccag tgattgggat tgtctctgtg
    48781 gataattatg atgatttgga ggatgcaact tctgagtcag atattagtca aatcaatagt
    48841 tttgtagcta attttatatc agagttttca gaaaaataca tgatgttttc tcgtcgggta
    48901 agtatggatc gattttatct atttactgac tacacggtgc ttgagggctt gatgaatgat
    48961 aaattttctg ttattgatgc tttcagagaa gagtcgaaac agagacagtt gcccttgacc
    49021 ttaagtatgg gattttctta tggcgatgga aatcatgatg agatagggaa agttgctttg
    49081 ctcaatttga acttggctga agtacgtggt ggcgaccagg tggttgttaa ggaaaacgac
    49141 gaaacgaaaa atccagttta ttttggtggt gggtctgctg cttcaatcaa gcgtacacgg
    49201 actcgtacgc gcgctatgat gacagctatt tcagataaga ttcggagtgt agatcaggtt
    49261 tttgtagtcg gtcacaaaaa tttagacatg gatgctttgg gctctgctgt aggtatgcag
    49321 ttgttcgcca gcaatgtgat tgaaaatagc tatgctcttt atgatgaaga acaaatgtct
    49381 ccagatattg aacgagctgt ttcattcata gaaaaagaag gagttacgaa gttgttgtct
    49441 gttaaggatg caatggggat ggtgaccaat cgttctttgt tgattcttgt agaccattca
    49501 aagacagcct taacattatc aaaagaattt tatgatttat ttacccaaac cattgttatt
    49561 gaccaccata gaagggatca ggattttcca gataatgcag tcattactta tatcgaaagt
    49621 ggtgcaagta gtgccagtga gttggtaacg gaattgattc agttccagaa ttctaagaaa
    49681 aatcgtttga gtcgtatgca agcaagtgtt ttgatggctg gtatgatgtt ggatactaaa
    49741 aatttcacct cgcgagtaac tagtcggaca tttgatgttg ctagctatct cagaacgcgc
    49801 ggaagtgata gtattgctat ccaggaaatc gctgcgacag attttgaaga atatcgtgag
    49861 gtcaatgaac ttattttaca ggggtgtaaa ttaggttcag atgtactaat agcagaggct
    49921 aaggacacga aatgctatga tacagttgtt attagtaagg cagcagatgc catgttagcc
    49981 atgtcaggta ttgaagcgag ttttgttctt gcgaagaata cacaaggatt tatctctatc
    50041 tcagctcgaa gtcgtagtaa actgaatgta caacggatta tggaagagtt aggcggtgga
    50101 ggccacttta atttggcagc agctcaaatt aaagatgtaa ccttgtcaga agcaggtgaa
    50161 aaactgacag aaattgtatt aaatgaaata aaggaaaagg agaaagaaga atgaaagtaa
    50221 tctttttagc agatgttaaa ggaaaaggta aaaaaggcga aattaaggaa gtaccaacag
    50281 ggtatgcgca aaactttctt atcaaaaaga atctagccaa agaagcgact gctcaagctg
    50341 taggtgaact tcgtggtaaa caaaaatcgg aagaaaaagc tcacgctgag atgattgcag
    50401 aaggaaaagc aattaaagca caacttgaag cagaagaaac tgttgtagaa tttgttgaaa
    50461 aagttggtcc agatggtcgt acctttggtt ctattaccaa taagaagatt gcagaagaat
    50521 tgcaaaagca atttggaatt aagattgata aacgtcatat tcaagtacaa gctccgattc
    50581 gagcggttgg tttgattgat gtgccagtga aaatctatca agatatcaca agtgtaatca
    50641 atcttcgtgt gaaagaagga taagtttaca ctttcttgac aagattgtaa aagaagggaa
    50701 gtctgatggc agaagtagaa gagttacgag tacaacctca agatatctta gctgagcaat
    50761 ccgttttagg ggctatcttt attgatgaga gtaaacttgt ttttgtgcga gaatacattg
    50821 agtctcggga cttttttaag tatgcccatc gtttgatttt ccaagccatg gtcgatttat
    50881 ccgatcgtgg tgatgccata gatgcaacaa cggttcgtac tatccttgat aatcaaggtg
    50941 atttacagaa tattggtggc ttgtcttact tggttgagat tgttaattct gtgccaactt
    51001 ctgctaatgc ggagtattat gctaagattg ttgcagaaaa agcaatgcta cgtcgtttaa
    51061 ttgccaagtt gacagagtct gtcaaccaag cttacgaagc gtcacaacca gctgatgaaa
    51121 ttattgctca ggcagaaaaa gggttgattg atgtcagtga aaatgcaaat cgaagcgggt
    51181 ttaagaacat tcgagatgtg ttgaatctca actttggaaa tctggaagct cgctcgcaac
    51241 aaacgaccga tattacaggt attgcgacag gttatcgtga tttggatcat atgacaacag
    51301 gacttcatga ggaggagttg attatcttag cagctcgtcc agcagttggt aagacagcat
    51361 ttgccttgaa tatcgctcag aatattggga ctaagttgga caaaacggtt gctatttttt
    51421 cactcgaaat gggtgcggaa agcttggtag atcgtatgtt agctgcagaa ggcttagtgg
    51481 agtcacattc tatccgtaca gggcaattga cagatgagga gtggcaaaaa tatactattg
    51541 ctcagggtaa tctagctaac gccagtatct atatcgatga tacgccaggt attcggatta
    51601 cagagattcg ttctcgttct cgtaaattgg ctcaagaaac tggaaatctt ggtttgattt
    51661 tgatagacta tttgcaactt atcacgggaa ctggtcgaga aaatcgtcaa caagaagttt
    51721 ctgaaatttc tcgtcagttg aaaatactag ccaaggaatt gaaggttcca gtaatcgctc
    51781 tgagtcagct ttctcgtggt gtagaacaac gtcaggacaa gagaccggtc ttgtctgata
    51841 ttcgtgaatc tgggtctatt gagcaggacg ctgatatcgt agcttttctc tatcgcgatg
    51901 actactatga acgtggtggt gaagaagagg agggtatccc aaataataag gtggaagtta
    51961 ttatcgagaa aaaccgtagt ggagctcgtg gaacagtgga attgattttc caaaaagaat
    52021 acaataaatt ttcaagtatc tcaaagaggg aggcataaga tgtcagatgc atttacagat
    52081 gtagccaaga tgaaaaaaat caaagaagaa atcaaggcac atgagggaca agtcgtagaa
    52141 atgactttgg agaatggtcg taagcgccaa aaaaatagat tgggtaagct aattgaagtt
    52201 tatccatctc tatttattgt ggagtttggg aatgtggaag gagataaaca agttaatgtt
    52261 tacgttgaat cctttactta ctcagatatt cttacagaaa agaatttgat tcattatctt
    52321 gactaaagtg agaaattttc tcactttttc ttttttctcc gaataattta ggtgaaggca
    52381 atcatcgctt tatattattt ttcaaggagg aagaatgaaa attttaccgt ttatagcaag
    52441 aggaacaagt tattacttga agatgtcagt taaaaagctt gttccttttt tagtagtagg
    52501 attgatgcta gcagctggtg atagtgtcta tgcctattcc agaggaaatg gatcgattgc
    52561 gcgtggggat gattatcctg cttattataa aaatgggagc caggagattg atcagtggcg
    52621 catgtattct cgtcagtgta cttcttttgt agcctttcgt ttgagtaatg tcaatggttt
    52681 tgaaattccg gcagcttatg gaaatgcgaa tgaatgggga catcgtgctc gtcgggaagg
    52741 ttatcgtgta gataatacac cgacgattgg ttccattact tggtctactg caggaactta
    52801 tggtcatgtt gcctgggtgt caaatgtaat gggagatcag attgagattg aggaatataa
    52861 ctatggttat acagaatcct ataataaacg aattataaaa gcaaacacga tgacaggatt
    52921 tattcatttt aaagatttgg atggtggcag tgttgggaat agtcaatcct caacttcaac
    52981 aggcggaact cattatttta agaccaagtc tgctatcaaa actgaacccc tagttagtgc
    53041 aactgtgatt gattactatt atcctggaga gaaggttcat tatgatcaaa ttctcgaaaa
    53101 agacggctac aagtggttga gttatactgc ctataatgga agctatcgtt atgttcaatt
    53161 ggaggctgtg aataaaaatc ctctaggtca ttctgttctt tcttcaacag gaggaactca
    53221 ttattttaag accaagtctg ctattaaaac tgaaccccta gttagtgcaa ctgtgattga
    53281 ttactattat cctggagaga aggttcatta tgatcaaatt ctcgaaaaag acggctacaa
    53341 gtggttgagt tatacggctt ataacggaag tcgtcgctat atacagctag agggagtgac
    53401 ttcttcacaa aattatcaga atcaatcagg aaatatctct agctatggat ccaataatag
    53461 ttcaactgtc ggttggaaga aaataaatgg tagttggtat catttcaaat caaatggttc
    53521 taaatcaaca ggatggctga aagacggttc tagctggtat tatttgaaat tatctggtga
    53581 aatgcagaca ggatggttaa aggagaatgg ctcgtggtat tatctgggta gttcaggggc
    53641 aatgaaaaca ggctggtacc aggtctctgg taagtggtat tattcttact cttcaggcgc
    53701 cttagctgtt aatacgacgg tggatggcta cagagtaaac agtgatggag aacgagtata
    53761 gaaaattgga gtaggagaaa tttcctgctc ttttctgtaa gcagtttcct tgacattttt
    53821 cttattttgc gctatcatat atacatataa tatatgggag tctgtgtaca gtctgagagg
    53881 aagtgttaaa cttcgaccgc acctgatctg ggtaatgcca gcggagggaa cgatacttag
    53941 tctaattttg caccttttcc atgtatggta aaggtttttc tttttttaaa aaaggaaaac
    54001 gagaagagga ggttcttatg aaagcaagca ttgccttgca agttttaccc ctagcacagg
    54061 ggattgatcg gatagctgtt attgatcagg tcattgctta tctgcaaact caagaagtga
    54121 cgatggtagt gacaccattt gaaacggtct tggaagggga gtttgatgag cttatgcgca
    54181 ttctaaaaga agcgctggaa gtggcagggc aggaggcaga caatgtcttt gccaatgtca
    54241 aaataaatgt aggagagatt ttaagtattg atgagaaact tgagaagtat actgagacgc
    54301 cacattagtc tattgggctt tctcggagtc ttgtcaatct ggcagttagc aggttttctt
    54361 aaacttctcc ccaagtttat cctgccgaca cctcttgaaa ttctccagcc ctttgttcgt
    54421 gacagagaat ttctctggca ccatagctgg gcgaccttga gagtggcttt actggggctg
    54481 attttgggag ttttgattgc ctgtcttatg gctgtgctca tggatagttt gacttggctc
    54541 aatgacctga tttaccctat gatggtggtt attcagacca ttccgaccat tgccatagct
    54601 cctatcctgg tcttgtggct aggttatggg attttgccca agattgtctt gattatctta
    54661 acgacaacct ttcccatcat cgttagtatt ttggacggtt ttaggcattg tgacaaggat
    54721 atgctgacct tgtttagtct gatgcgggcc aagccttggc aaatcctgtg gcattttaaa
    54781 atcccggtta gcctgcctta cttttatgca ggtctgaggg tcagtgtctc ctacgccttt
    54841 atcacaactg tggtatctga gtggttggga ggttttgaag gtcttggtgt ttatatgatt
    54901 cagtctaaaa aactgtttca gtatgatacc atgtttgcca ttattattct ggtgtcgatt
    54961 atcagtcttt tgggtatgaa gctggtcgat atcagtgaaa aatatgtgat taaatggaaa
    55021 cgtacttaaa atagagcgtt tttgaaaaag aaaagaggaa atcaaaatga agaaaacatg
    55081 gaaagtgttt ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg cctgtggtca
    55141 aggaactgct tctaaagaca acaaagaggc agaacttaag aaggttgact ttatcctaga
    55201 ctggacacca aataccaacc acacagggct ttatgttgcc aaggaaaaag gttatttcaa
    55261 agaagctgga gtggatgttg atttgaaatt gccaccagaa gaaagttctt ctgacttggt
    55321 tatcaacgga aaggcaccat ttgcagtgta tttccaagac tacatggcta agaaattgga
    55381 aaaaggagca ggaatcactg ccgttgcagc tattgttgaa cacaatacat caggaatcat
    55441 ctctcgtaaa tctgataatg taagcagtcc aaaagacttg gttggtaaga aatatgggac
    55501 atggaatgac ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga
    55561 ctttgagaag gttgaaaaag taccaaataa cgactcaaac tcaatcacac cgattgccaa
    55621 tggcgtcttt gatactgctt ggatttacta cggttgggat ggtatccttg ctaaatctca
    55681 aggtgtagat gctaacttca tgtacttgaa agactatgtc aaggagtttg actactattc
    55741 accagttatc atcgcaaaca acgactatct gaaagataac aaagaagaag ctcgcaaagt
    55801 catccaagcc atcaaaaaag gctaccaata tgccatggaa catccagaag aagctgcaga
    55861 tattctcatc aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca
    55921 aaaatacttg tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc
    55981 tcgctggaat gctttctaca aatgggataa agaaaatggt atccttaaag aagacttgac
    56041 agacaaaggc ttcaccaacg aatttgtgaa ataatgacag aaattagact agagcacgtc
    56101 agttatgcct atggtcagga gaggatttta gaggatatca acctacaggt gacttcaggc
    56161 gaagtggttt ccatcctagg cccaagtggt gttggaaaga ccaccctctt taatctaatc
    56221 gctgggattt tagaagttca gtcagggaga attgtccttg atggtgaaga aaatcccaag
    56281 gggcgcgtga gttatatgtt gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga
    56341 aatatcattc tgcccctctt gattcaaaag gtggataagg cagaagctat ttcccgagcg
    56401 gataaaattc ttgcgacctt ccagctgaca gctgtaagag acaagtatcc tcatgaactt
    56461 agcggtggga tgcgccagcg tgtagcctta ctccggacct acctttttgg gcacaagctc
    56521 tttctcttag atgaggcctt tagcgccttg gatgagatga caaagatgga actccacgct
    56581 tggtatcttg agattcacaa gcagttgcag ctaacaaccc tgatcatcac gcatagtatt
    56641 gaggaggccc tcaatctcag cgaccgcatc tatatcttga aaaatcgccc tgggcagatt
    56701 gtttcagaaa ttaaactaga ttggtctgaa gatgaggaca aggaagtcca aaagattgcc
    56761 tacaaacgtc aaatcttggc agaattaggc ttagataagt agaaaaatag ggagttggtg
    56821 aagattatcc tttaccagcg ccctttttct tttaaaaatg agaaaatttc ggtataatag
    56881 tcaaacaagg tcaaggttta aagagagagg tgggtttgtt atgagattta aaaatacatc
    56941 ggatcatatt gaggcctaca tcaaggcgat tttagatcaa tctggtatcg tggagttgca
    57001 acggagtcag ttggcagata cctttcaggt tgttcctagt cagattaact acgtgatcaa
    57061 gacacgcttt acggaaagta gaggctactt ggttgaaagt aagcgtggtg gcggaggcta
    57121 cattcgtata ggacggattg agttttctag tcatcatgaa atgctccggg agctgcttta
    57181 ctcgattggt gagcgagtca gtcaagaaat ttatgaggat attctccagc ttttggttga
    57241 gcaggaattg atgaccaagc aggagatgaa tttgctagaa tcagtagctt tggatcgcgt
    57301 tttaggagaa gaagctccag ttgttcgagc aaacatgcta cgtcagatca tacaagaggt
    57361 agatagaaaa gggaagtaag atgaactatt caaaagcatt gaatgaatgt atcgaaagtg
    57421 cctacatggt tgctggacat tttggagctc gttatctaga gtcttggcac ttgttgattg
    57481 ccatgtctaa tcacagttat agtgtagcag gggcaacttt aaatgattat ccgtatgaga
    57541 tggaccgttt agaagaggtg gctttggaac tgactgaaac ggactatagc caggatgaaa
    57601 cctttacgga attgccgttc tcccgtcgtt tgcaggttct ttttgacgaa gcagagtatg
    57661 tagcgtcagt ggtccatgct aaggtgctag ggacagagca cgtcttctat gcgattttgc
    57721 atgatggcaa tgccttggca actcgtatct tggagagggc tggtttttct tatgaagaca
    57781 agaaagatca ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg gcaggctgga
    57841 ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac agtagctgac aagcaaaatt
    57901 ctatggccaa tatgatgggc atgccgcaga ctcctagtgg tggtctcgag gattatacgc
    57961 atgatttgac agagcaagcg cgttctggca agttagaacc agtcatcggt cgggacaagg
    58021 aaatctcacg tatgattcaa atcttgagcc ggaagactaa gaacaaccct gtcttggttg
    58081 gggatgctgg tgtcgggaaa acagctctgg cgcttggtct tgcccagcgt attgctagtg
    58141 gtgacgtgcc tgcggaaatg gctaagatgc gcgtgttaga acttgatttg atgaatgtcg
    58201 ttgcagggac acgcttccgt ggtgactttg aagaacgcat gaataatatc atcaaggata
    58261 ttgaagaaga tggccaagtc atcctcttta tcgatgaact ccacaccatc atgggttctg
    58321 gtagcggaat tgattcgact ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg
    58381 gaactttgag aacggttggt gccaccactc aggaagaata tcaaaaacat atcgaaaaag
    58441 atgcggctct ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt gtggcagata
    58501 gtatgactat tttacaaggt ttgaaggcga cttatgagaa acatcaccgt gtacaaatca
    58561 cagatgaagc ggttgaaaca gcggttaaga tggctcatcg ttatttaacc agtcgtcact
    58621 tgccagactc tgctatcgac ctcttggacg aagcagcagc aacagtgcaa aataaggcaa
    58681 agtatgtaaa agcagacgat tcagatttga gtccagctga caaggccctg atggatggca
    58741 agtggaaaca ggcagcccag ctaatcgcaa aagaagagga agtacctgtc tacaaagact
    58801 tggtgacaga gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc ccagttcaaa
    58861 aactgactca gactgacgct aagaaatatc taaatcttga agcagaactc cataaacggg
    58921 ttatcggtca agatcaagct gtttcaagta ttagtcgtgc gattcgccgt aatcagtcag
    58981 gaattcgcag tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg
    59041 gtaagaccga gttggccaag gctttggcag aagttctctt tgatgacgaa tcagccctta
    59101 tccgctttga tatgagtgag tatatggaga aattcgcagc cagccgtcta aatggagctc
    59161 ctccaggcta tgtgggttac gaagaaggtg gggagttgac agagaaggtt cgcaataaac
    59221 cctattccgt tctcctcttt gatgaggtag agaaggctca cccagatatc tttaatgttc
    59281 tcttgcaggt tctggatgac ggtgtcttga cagatagcaa gggacgcaag gtcgattttt
    59341 caaataccat tatcattatg acatcgaacc taggtgcgac tgcccttcgt gatgataaga
    59401 ctgttggttt tggggctaag gatattcgtt ttgaccagga aaatatggaa aaacgcatgt
    59461 ttgaagaact gaaaaaagct tatagaccgg aattcatcaa ccgtattgat gagaaggtgg
    59521 tcttccatag cctatctagt gaccatatgc aggaagtggt gaagattatg gtcaagcctt
    59581 tagtggcaag tttggctgaa aaaggcattg acttgaaatt acaagcttca gctctgaaat
    59641 tgttagcaaa tcaaggatat gacccagaga tgggagctcg cccacttcgc agaaccctgc
    59701 aaacagaagt ggaggacaag ttggcagaac ttcttcttaa gggagattta gtggcaggca
    59761 gcacacttaa gattggtgtc aaagcaggcc agttaaaatt tgatattgca taaaagaata
    59821 aaagtatcag catctgacca taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc
    59881 aaactaggca gctagccgca ggttgctcaa aacactggtt tgaggttgca gatagagctg
    59941 acgtagtttg aagagatttt cgaagagtat gaaactaaaa cctatagctt ctaaacgatc
    60001 cgtggttttc accattcaac acaaaattca tatgtttatt accctccgtc gtatttgtct
    60061 tagagcgtat gtagtagaaa aagagcagtc ttatctgaaa tttttattct ttcaaaagag
    60121 acctgtttct tttttgcatg tcaaatccgt tctagctggt atttgaaaaa tcaaactaat
    60181 attcaatgaa aatcaaagaa taaactaggc agttagccgc aggttgctca aaacactgtt
    60241 tttagattgt agatagagct gacgtggttt gaagagattt tcgaagagta taagctgcaa
    60301 gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa agtagcggat aaatgaaatc
    60361 cattccatta tcatagatga taggctggta ggaaattttc aaatagcata caggaaatag
    60421 atgtatggag ttctggtagt agaaagggag agagatgaac attttagttg cagatgacga
    60481 ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa gagggttatc atgtcattat
    60541 ggctaaggat ggacaagagg tcttggaaaa atttcaagat ctccctatcc atctcatggt
    60601 attggattta atgatgccta ggaagagtgg ttttgaagtg ttaaaagaaa tcaatcaaaa
    60661 gcacgatatt cctgtcatcg tcttgagtgc tctgggagat gaaactactc agtcacaggt
    60721 atttgatctc tatgctgatg atcatgtgac aaaacctttt tctttggtac tgcttgtcaa
    60781 gcgtattaag gcgcttatca gacgttacta cgtcatagag gatatttggc gatatcagga
    60841 tgtaacagtg gattttacct cttacaaagc acattataaa aatgaagaaa ttgatctcaa
    60901 accaaaggaa ttactggtac taaagtgttt gattcagcat aaaaatcaag ttttaagtag
    60961 agagcagata ttggaagaaa tttcaaaaga tgtagctgat ttaccttgtg atagggtcgt
    61021 tgatgtctat attcgtactc ttcgcaaaaa attagcttta gattgtatcg tgactgtgaa
    61081 aaatgttggg tataagatta gcttatgata aaaaatccta aattattaac caagtctttt
    61141 ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca ttcatatagc tatttatttg
    61201 acctttcctt tttattatat tcaactggag ggggaaaagt ttaatgagag cacaagagtg
    61261 tttacggagt atttaaagac taagacatct gatgaaattc caagcttact ccagtcttat
    61321 tcaaagtcct tgaccatatc tgctcacctt aaaagagata ttgtagataa gcggctccct
    61381 cttgtgcatg acttggatat taaagatgga aagctatcaa attatatcgt gatgttagat
    61441 atgtctgtta gtacagcaga tggtaaacag gtaacagtgc aatttgttca cggggtggat
    61501 gtctacaaag aagcaaagaa tattttgctt ttgtatctcc catatacatt tttggttaca
    61561 attgcttttt cctttgtttt ttcttatttt tatactaaac gcttgctcaa tcctcttttt
    61621 tacatttcag aagtgactag taaaatgcaa gatttggatg acaatattcg ttttgatgaa
    61681 agtaggaaag atgaagttgg tgaagttgga aaacagatta atggtatgta tgagcacttg
    61741 ttgaaggtta tttatgagtt ggaaagtcgt aatgagcaaa ttgtaaaatt gcaaaatcaa
    61801 aaggtttcct ttgtccgcgg agcatcacat gagttgaaaa cccctttagc cagtcttaga
    61861 attatcctag agaatatgca gcataatatt ggagattaca aagatcatcc aaaatatatt
    61921 gcaaagagta taaataagat tgaccagatg agccacttat tggaagaagt actggagtct
    61981 tctaaattcc aagagtggac agagtgtcgt gagactttga ctgttaagcc agttttagta
    62041 gatattttat cacgttatca agaattagct cattcaatag gtgttacaat tgaaaatcaa
    62101 ttgacagatg ctaccagagt cgtcatgagt cttagggcat tggataaggt tttgacaaac
    62161 ctgattagta atgcaattaa atattcagat aaaaatgggc gcgtaatcat atccgagcaa
    62221 gatggctatc tctctatcaa aaacacatgt gtacctctaa gtgaccaaga actagaacat
    62281 ttatttgata tattctatca ttctcaaatc gtgacagata aggatgaaag ttccggtttg
    62341 ggtctttaca ttgtgaataa tattttagaa agctatcaaa tggactatag ttttctccct
    62401 tatgaacacg gtatggaatt taagattagc ttgtagacag attagttttt tattaaagtt
    62461 catatagggt taacataagt gtgttattct ttgtgtagat aaaagaaagg atactaatat
    62521 ggtattagcg attattttag taacattctt tattcgattg atttttttaa agcgttcgat
    62581 agagaatgag aaacgaatcc ttagcaatgg cgggaaagaa tttggagttg agaatacaaa
    62641 acgattaact atggctcata ttgtttttta tctctcttgc ttggttgagg caatggtgca
    62701 caagacaatt tttgatggca tgggcatggt tggtttagtc ttgcttattt tttctatgct
    62761 gatgttgatg ttggtgattc acttgttggg agatatttgg acagtgaagc ttatgcttgt
    62821 caataatcac aaatatgtag atcatatctt gtttaggaca gtaaaacatc ctaattactt
    62881 tttaaatatt cttcctgagt tgattggctt gaccttgttg agtcatgctt atgtgacttt
    62941 tgttttagtt tttccagttt atgcagttat tttgtatcga cgaatagctg aagaggaaaa
    63001 gctattacat gaagttataa tcccaaatgg aagcataaag agataaatac aaaattcgat
    63061 ttatatacag ttcatattga agtgatatag taaggttaaa gaaaaaatat agaaggaaat
    63121 aaacatgttt gcatcaaaaa gcgaaagaaa agtacattat tcaattcgta aatttagtat
    63181 tggagtagct agtgtagtag ttgccagctt gttcttagga ggagtagtcc atgcagaagg
    63241 ggttagaagt gggaataact ccacggttac atctagtggg caagatatat cgaagaagta
    63301 tgctgatgaa gtcgagtcgc atctacaaag tatattgaag gatgtcaata aaaatttgaa
    63361 aaaagttcaa catacccaaa atgtcgactt caacaaaaag ttgagcgcaa ttaaaacgaa
    63421 gtatttgtat gaattaagtg ttttagaaga gaagtcggaa gctgagttga cgtcaaaaac
    63481 aaaagaaaca aaagaagagt tagacgcagc ttttgagcag tttaaaaaag atacattatc
    63541 aacagaacca gaaaaaaagg tagcagaagc tcagaagaag gtagcagaag ctaagaaaaa
    63601 agccgaggtt caaaaagaag aagatcaccg taactaccca accattactt acaaaacgct
    63661 tgaacttgaa attgctgagt tcgatgtgaa agttaaagaa gcggagcttg aactagtaaa
    63721 aaaggaagct gacgaatctc gaaacgaggg cacaattaac caagcaaaag cgaaagttga
    63781 gagtgaaaaa gctgaggcta caaggttaaa aaaaatcaag acagatcgtg aaaaagcaga
    63841 agaagaagct aaacgaagag cagatgctaa agagcaagat gaatcaaaga ggcgaaagag
    63901 tcgggtaaaa cgaggagatc ttggagagca agcaacacct gataaaaaag aaaatgatgc
    63961 gaagtcttca gattctagcg taggtgaaaa aactcttcca agcccatccc tgaaaccagg
    64021 aaaaaaggta gcagaagctg agaagaaggt tgaagaagct gataaaaaag ccaaggctca
    64081 aaaagaagaa gatcgccgta actacccaac caatacttac aaaacgcttg aacttgaaat
    64141 tgctgagtcc gatgtgaaag ttaaagaagc ggagcttgaa ctagtaaaag aggaagctaa
    64201 ggaacctcaa aacgaggaaa aaattaagca agcaaaagcg aaagttgaga gtaaaaaagc
    64261 tgaggctaca aggttagaaa aaatcaagac agatcgtaaa aaagcagaag aagaagctaa
    64321 acgaaaagca gcagaagaag ataaagttaa agaaaaacca gctgaacaac caaaaccagc
    64381 gccggctcct caaccagaaa aaccagctcc aaaaccagag aatccagctg aacaaccaaa
    64441 agcagaaaaa ccagctgatc aacaagctga agaagactat gctcgtagat cagaagaaga
    64501 atataatcgc ttgactcaac agcaaccgcc aaaaactgaa aaaccagctc cagcaccaca
    64561 accagagcaa ccagctccag caccaaaaac aggctggaaa caagaaaacg gtatgtggta
    64621 cttctacaat actgatggtt caatggcaac aggatggctc caaaacaacg gttcatggta
    64681 ctatctaaac gctaatggtg ctatggcgac aggatggctc caatacaatg gctcatggta
    64741 ttacctcaac agcaatggcg ctatggcgac aggatggctc caatacaatg actcatggta
    64801 ttacctcaac gctaatggtg ctatggagac aggttggcta gaatacaatg gttcatggta
    64861 ttacctcaac gctaatggtg atatggcgat aggatggctc caatacaatg gctcatggta
    64921 ttacctcaac gctaatggtg atatggcgac aggatggctc caatacaatg gttcatggta
    64981 ctacctaaac agcaatggtg ctatggtaac aggatggctc caaaacaatg gctcatggta
    65041 ctacctaaac gctaacggtt caatggcaac aggttgggtg aaagatggag atacctggta
    65101 ctatcttgaa gcatcaggtg ctatgaaagc aagccaatgg ttcaaagtat cagataaatg
    65161 gtactatgtc aatggctcag gtgcccttgc agtcaacaca actgtagatg gctatggagt
    65221 caatgccaat ggtgaatggg taaactaaac ctaatataac tagttaatac tgacttcctg
    65281 taagaactct ttaaagtatt ccctacaaat accatatcct ttcagtagat aatataccct
    65341 tgtaggaagt ttagattaaa aaataactct gtaatctcta gccggattta tagcgctaga
    65401 gactacggag tttttttgat gaggaaagaa tggcggcatt caagaggctc tttaagagag
    65461 ttacgggttt taaactatta agccttctcc aattgcaaga gggcttcaat ctctgccagg
    65521 gtgctagctt gcgaaatggc tccacggagt ttggcagcgc cagatgttcc acggaggtag
    65581 tgaggagcga ggccgcggaa ttcacgaact gcgacgtttt ctcctttgag gttaatcaat
    65641 cgtttcaagt gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc aggtaggatt
    65701 tctcctgttt caaagtaatg gttgatttgg ttgaagaggt aaggatttcc catggcagct
    65761 cggccaatca tgactgcgtc agcaccaact tcttcgatgc gttgcttggc ttcttggaca
    65821 gtacggatat caccgttggc gatgaatgga atcttggtta gagcttgggc aaccttgtaa
    65881 agggtctcaa ggtctgcgtg gccagtatac atttgttcac gggtacggcc atgcatggcg
    65941 agggcagaaa cacctgcagc ttcagcagcg agggcatttt ctactgccag agatgggtcc
    66001 gcccagccgg tacgcatttt gacagtaagt gggatatcaa ggacagactg gaccttgttg
    66061 atgatagagt agatcttgtc aggatccttg agccacatag caccagcttc gttcttcacg
    66121 attttgttga cagggcagcc catgttgata tcgacgatat cggtcttggt gttttcttgg
    66181 atgaattctg ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg gatagagaca
    66241 gggttttcgc cctcatcgat atgaagcatg tgcagggttt tttcgttgtt gtattggatt
    66301 cccttgtcag agaccatttc cattacaacg agtccagctc cgagctcttt tgcgatggta
    66361 cgaaaggctg agttggtcac gccagccata ggcgctaaaa cggtacgatt gggaatctca
    66421 acattgccaa tcataaaagg tgtattaaga tttgtcacaa atgagttcct ccaggtcctt
    66481 ttcatcaaag ttgtaagtag tttggcagaa ttgacaagtg atttctgcgc cgtggtcttc
    66541 ctctttcatt tcctgtaagt ctgagcttgg aaggctggca agagcgttca taaagcgttc
    66601 atggctacag tcacattgga aacggatttc ttcttcagaa agacgcttgt aggcttcgtc
    66661 cccgtagata gccttgagga gggcttcgat atggtcgtcg ctttcgagaa gagtagagat
    66721 agctggcatt tcttggatgc gtttttcaaa gcgagcaatt tcttctttct tggctcctgg
    66781 caagacttga actaggaaac cacctgcaac cttgaccttg tcttcctcgt ccaaaaggac
    66841 attgaggccg accgctgaag gcgtttgttg gctttcagta aggtaaaagg caaggtcttc
    66901 accgatttct ccagagatga ggggagttat agagttgtaa ggatttccag taccgtagtc
    66961 tgtgataacg aggaattgac catttccaac aaaaggtccg actaggactt caccagtcgc
    67021 agtctttttg atgtcaacac caggattttg aacgtagcct ttgacgttcc ccttggtatc
    67081 agcgacggtg ataatagcac ctagagagct agatcccaac accttaactg taagtttggt
    67141 atttcctttt tcattggctg cgagaatctg gctggcgata agagttcgac caagcgctac
    67201 agttgagcta gcttgggttt gatgtttttc ttgagcagtg cggacggttt ccgtgctatc
    67261 aaggacaaaa gcacgaaagg ctccgctttc tgatatagtt ttaataattt tatccatagc
    67321 tactatttta gcataaaaat gcccaaaggg ggagccgtgt gtttactgat tttcaggata
    67381 atggaccagg aaatcagcat gaaaataaaa agagaaacag attattttag catttgtaag
    67441 atttatgcta tgcttaaggt agaaaatgaa aggggtaaca aatgtattta ggagatttga
    67501 tggagaaagc cgagtgtggt caattttcaa tcctttcctt tctattacaa gagtctcaga
    67561 cgaccgtcaa ggctgtaatg gaagaaacag gattttcaaa agcaacccta accaaatatg
    67621 tcaccctgct caatgacaag gctttggata gtggcttaga gctgactatt cactcagaag
    67681 atgaaaatct gcgtctgtct atcggtgcag ctaccaaggg gagagatatt cggagcttgt
    67741 ttttggatag tgctgttaaa taccagattt tggtttatct tctctaccac caacagtttt
    67801 tagcccatca gctggctcaa gaattggtga ttagcgaggc tacgcttggt cgtcacttgg
    67861 ctggtttaaa tcagattttg tcagaatttg atttatccat ccaaaatgga cgttggcgag
    67921 gtccagagca tcagattcgc tatttctatt tctgtctttt ccgaaaggtc tggtcgagtc
    67981 aggaatggga aggtcacatg cagaaaccag agagaaaaca ggagattgcc aatttagagg
    68041 aaatctgcgg tgcaagtttg tctgccgggc agaaattgga cttggttctc tgggctcaca
    68101 tcagtcaaca acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa gagaaaatgc
    68161 gagggtattt tgacaatatc ttctatcttc gtttgctgag aaaggttccg tccttttttg
    68221 ctgggcaaca tattccacta ggagttgagg atggtgagat gatgatattc ttctcttttc
    68281 tcctatctca tcgcattctt cctcttcata ctatggagta tattcttggt tttggagggc
    68341 agttggcaga tttactgacg caattgattc aagaaatgaa gaaggaggaa ctattggggg
    68401 attatacaga ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa gtctatctct
    68461 ataagggcta tattttacag gatcgctaca agtaccagtt agagaatcgt catccatatt
    68521 tactgatgga acatgatttt aaagagacag cagaggagat ttttcatgct ctacctgctt
    68581 ttcaacaggg gacagattta gataagaaga ttctctggga atggctccag ttaatcgaat
    68641 atatggctga aaacggtggc cagcatatgc ggattggtct ggatttgaca tctggttttc
    68701 ttgtcttttc aaggatggca gccattttga aacggtattt agaatacaat cgttttatta
    68761 ccattgaagc ttataaccct agtcggcatt atgatttgct ggttaccaat aacccgattc
    68821 ataagaagga acagacacca gtctattatt taaaaaatga cttggatatg gaagatttgg
    68881 cagggattcg tcagttatta ttcacttaaa aggcttggtt aatccaggtc ttttttgtga
    68941 aattcacaca atctcctcac atttttttaa aaattaaaaa aagttgataa acaagaaagc
    69001 gctttatttt gtatactagt aagtgtaaag aggaaacacc tcaagatctt tatcaggagg
    69061 acagtatatg tcacaagaaa aatacatcat ggccattgac cagggaacta caagttctcg
    69121 tgccatcatt ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag agtttaccca
    69181 gattttccct caggcaggtt gggttgagca caatgccaat gaaatttgga actctgttca
    69241 gtcagttatt gcgggtgctt tcatcgaaag tggtgtcaag ccaaatcaaa tcgaggcaat
    69301 cgggattacc aaccaacgtg aaacaacggt tgtctgggat aagaaaacag gacttcctat
    69361 ctacaatgct atcgtttggc agtcacgcca gacagcacct ttggctgagc aactaaaaag
    69421 ccaaggttat gtggaaaaat tccatgaaaa gactggtttg attattgatg cttacttctc
    69481 tgctaccaag gttcgttgga ttttggatca tgtagaaggc gctcaagagc gagcagaaaa
    69541 aggggaattg ctctttggta ctatcgatac ttggttggtt tggaaattga ctgacggtgc
    69601 ggttcacgtg actgactact caaatgcagc tcgtaccatg ctttataaca ttaaagaact
    69661 caaatgggat gatgagattt tggaaatcct taacattccg aaggctatac ttccagaagt
    69721 tcgttctaac tccgaaatct acggcaagac agctccattc catttctacg gtggagaggt
    69781 gccaatctca ggtatggctg gggaccaaca agcagccctc tttggacagt tggcttttga
    69841 gccaggtatg gttaagaata cttatggaac aggctctttc atcatcatga atactgggga
    69901 agagatgcag ttgtctgaaa acaacctctt gacaaccatt ggttacggaa tcaacggtaa
    69961 ggtttattat gccttggaag gttctatctt catcgcagga agtgctattc agtggcttcg
    70021 tgacggtctt cgcatggttg aaaattcacc agaatctgaa aaatacgctc gtgattctca
    70081 caacaacgat gaagtttatg tcgttccagc ctttacaggt ctaggcgctc catactggaa
    70141 ccaaaatgct cgtggttccg tctttggttt gactcgtgga acaagcaaag aagactttat
    70201 caaggcgact ttgcaatcta ttgcttatca agtgcgtgac atcatcgaca ccatgcaaat
    70261 ggatactcag accgccattc aagtactgaa ggtggatggt ggtgcagcca tgaacaactt
    70321 cctcatgcag ttccaggcgg atattttagg cattgatatt gcacgtgcta aaaacttgga
    70381 aacaacagct ctaggagcgg ccttcctagc aggtttatca gtagggtact ggaaagactt
    70441 ggacgagttg aaactcttga acgagacagg agaactcttt gagccatcta tgaatgaatc
    70501 tcgcaaggaa caactctaca agggctggaa gaaggctgtg aaagcaactc aagtctttgc
    70561 ggaagtagac gactaatact ggcagaataa agcgatttat ttagaaagtg tgtaaatatg
    70621 gaattttcaa agaaaacacg tgaattgtca attaaaaaaa tgcaggaacg caccctggac
    70681 ctcttgatta tcggtggagg aatcacagga gctggtgtag ccttgcaggc ggcagctagc
    70741 ggtcttgaga ctggtttgat tgaaatgcaa gactttgcag aaggaacatc tagtcgttca
    70801 acaaaattgg ttcacggagg acttcgttac ctcaaacaat ttgacgtaga ggtggtctca
    70861 gatacggttt ctgaacgtgc agtggttcaa caaatcgctc cacacattcc aaaaccagat
    70921 ccaatgctct taccagttta cgatgaagat ggagcaacct ttagcctctt ccgtcttaaa
    70981 gtagccatgg acttgtacga cctcttggca ggtgttagca acacaccaac tgcgaacaag
    71041 gttttgagca agaaagaagt cttggaacgc cagccaaact tgaagaagga aggcttggta
    71101 ggaggtggag tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat tgaaaacatc
    71161 aaacgtgcca accaagacgg tgccctcatt gccaaccacg tgaaggcaga aggcttcctc
    71221 tttgacgaaa gtggcaagat tacaggtgtt gtagctcgtg atctcttgac agatcaagta
    71281 tttgaaatca aggcccgtct ggttattaat acaacaggtc cttggagtga taaagtacgt
    71341 aatttgtcta ataagggaac gcaattctca caaatgcgcc caactaaggg agttcacttg
    71401 gtagtggatt caagcaaaat caaggtttca cagccagttt acttcgacac aggtttgggt
    71461 gacggtcgta tggtctttgt tctcccacgt gaaaacaaga cttactttgg tacaactgat
    71521 acagactaca caggtgattt ggagcatcca aaagtaactc aagaagatgt agattatcta
    71581 cttggcattg tcaacaaccg ctttccagaa tccaacatca ccattgatga tatcgaaagc
    71641 agctgggcag gtcttcgtcc attgattgca gggaacagtg cctctgacta taatggtgga
    71701 aataacggta ccatcagtga tgaaagcttt gacaacttga ttgcgactgt tgaatcttat
    71761 ctctccaaag aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct tgaaagtagc
    71821 acatctgaga aatatttgga tccatctgca gtttctcgtg ggtctagctt ggaccgtgat
    71881 gacaatggtc ttttgactct tgctggcggt aaaatcacag actaccgtaa gatggctgaa
    71941 ggagctatgg agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag ctttaaattg
    72001 atcaattcta aaacttaccc tgtttcaggt ggagaattga acccagcaaa tgtggattca
    72061 gaaatcgaag cctttgcgca acttggagta tcacgtggtt tggatagcaa ggaagctcac
    72121 tatctggcaa atctttacgg ttcaaatgca ccgaaagtct ttgcacttgc tcacagcttg
    72181 gaacaagcgc caggactcag cttggcagat accttgtccc ttcactatgc aatgcgcaac
    72241 gagttggctc ttagcccagt tgacttcctt cttcgtcgta ccaaccatat gctctttatg
    72301 cgtgatagct tggatagcat cgttgagcca gttttggatg aaatgggacg attctatgac
    72361 tggacagaag aagaaaaagc aacttaccgt gctgatgtcg aagcagctct cgctaacaac
    72421 gatttagcag aattaaaaaa ttaagaaaaa ataaaagagg tggagggcag cattccttgt
    72481 cgcccgtccc ttctttttaa tggagacaga aagatgatga atgaattatt tggagaattt
    72541 ctagggactt taatcctgat tcttctagga aatggtgttg ttgcaggtgt ggttcttcct
    72601 aaaaccaaga gcaatagctc aggttggatt gtgattacta tgggttgggg gattgcagtt
    72661 gcggttgcag tctttgtatc tggcaagctc agtccagctc atttaaatcc agctgtgaca
    72721 gttggtgtag ctttaaaagg tgacttgctt tgggcttccg ttttgcctta tatcttagcc
    72781 cagttcgcag gggccatgct gggtcagatt ttggtttggt tgcaattcaa acctcactat
    72841 gaggcagaag aaaatgcagg caatatcctg gcaaccttca gtactggacc agccatcaag
    72901 gatactgtat caaacttgat tagcgaaatc cttggaacct ttgttttggt gttgacaatc
    72961 tttgctttgg gtctttacga ttttcaggca ggtatcggaa cctttgcagt gggaactttg
    73021 attgtcggta tcggtctatc actaggtggg acaacaggtt atgccttgaa cccagctcgt
    73081 gaccttggac ctcgtatcat gcacagcatc ttgccaattc caaacaaggg agacggagac
    73141 tggtcttacg cttggattcc tgttgtaggc cctgttatcg gagcagcctt ggcagtgctt
    73201 gtattctcac ttttctagtt tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg
    73261 ccttaccgta ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattttcatt
    73321 gagtattaga aaacaattat gttgatagag cttgggcaag agcccaattt cagcaaaaaa
    73381 tgaagtaaat cttctcataa taaaacgcat catatcaagc acgaaaattc cacgaggtca
    73441 actacagtca gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc aaaaagcaag
    73501 cacctgcaag caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa ttagacccaa
    73561 aaatcgttga tatgctagta gaatttcaca agtcacaagg cactttggaa actcccgagg
    73621 cgcaagcaga aatcgcccaa aaacgtgaag aaatcgagca aaggagagct gagcttgagg
    73681 ataaaaaaca agagcttttg aaccgcttga acaaatagag tttcgcaagt attatgctta
    73741 caaattactt gagcaattaa ctaaaatata aaccctgcct agatataaag gcagagttta
    73801 tattttagaa attcacgtag gttgttacgg tttttacata cccagtatag tttgagtttc
    73861 tatagtattc agtgataaac ttccattttc tttgagcaac atggatataa gtacttgtta
    73921 tgtagtatgg atatgggctt tgtgaatcca agtaagactg ataagcttgt ataccaaaat
    73981 atgctccacc aattattgca ccccatggac cccccaataa agcacctatc ctaccaatca
    74041 tataactgat tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat
    74101 gtattgtgtt gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt
    74161 cgatttcatt cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac
    74221 gtcgttcaat agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta
    74281 aaatatttac ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac
    74341 cagatacaac tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg
    74401 aaatgctaga catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag
    74461 acataacgga aactcttttg tatttttgat ttttttcaac ttttattata caataaaacc
    74521 aaataaaaag aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt
    74581 ttgatcgtta tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat
    74641 ttagacacag aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca
    74701 ttcgcttggg tctgctctac aataaaaaac aataaaaaat aaatagacgt attttcaaaa
    74761 aaaaaaaaaa aatgcatatt tatattagca aaatgacgat ttaaatcgtc gtttttttgt
    74821 agtacgacgg gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt
    74881 gaacccaata gcgattccca agcctgacta tcgtgaggta gcggattaaa acggtctggg
    74941 gatagaccgt tttaagtctg acgcaggaaa taagaatcgt cagaggaagg gatagcgaaa
    75001 tcgtggctct acgaacagga acgtgatagt aaggcgtata tagcggataa ggaggcttca
    75061 aactctaaag tccaaaaagg tagtcgtaac ctatatgtgt aaatcacgag agtaattgaa
    75121 ttcggactaa ggtttgtgtg aaaaagataa atctttctag agtctaaaga ctctgcgtca
    75181 gatttcctat tttcactgta accttttaac gtcctcatat cttgtataaa cgaggaaaga
    75241 tgtacgactt atcccgtgag gtttcatgag cgctgaaagc gtagtaacaa cgaatcatga
    75301 gaagtcagcc gagcccatag tagtgaggaa acttctgtag tggaagtgga gcgaaggggt
    75361 gaatactcaa acagtctggg gagagactgt ttgaggtctg tcgctagaaa gagaaaacga
    75421 cagatcgaag taatcctact tcacttgtgt ctgtaaaatg agtggtctga tagaactgga
    75481 ctttgacacg taatgactag atgaaggttc accaatataa gatgtccctc aggcaccaaa
    75541 acaagaaagg aatacgcaca tgtcaaaact gctagataag atattatcac gcgaaaatat
    75601 gctggaagcc tacaatcaag taaaatccaa taaaggctca gctgggattg atggaatgac
    75661 tatcgaagag atggataatt atctcagaca aaactggcgc ttgactaagg aactgataaa
    75721 acagagaaaa tataagcctc aaccagttct taaagttgag atacctaaac cagacggagg
    75781 catccgtcaa ctaggaattt caacagttat ggatagaatg attcaacagg ccattgtcca
    75841 agtcatgagc cccatttgtg aaccccattt ctcagatacg agttatggtt tcagaccaaa
    75901 taggtcatgt gaaaaagcca tcatgaagct cttagaatac ttaaatgacg gctatgagtg
    75961 gatagtggat atagacctag agaaattttt cgatacagtt cctcaagata gattgatgtc
    76021 cttagtacat aacattatcg aagacggaga tacggaatcc ttgattcgta agtatcttca
    76081 ttcaggtgtt atcattaatg gtcaacgtta taaaacacta gttggtacac cacagggagg
    76141 aaatttatct cctctcttat ccaatatcat gcttaatgaa ttggacaagg aattagaaaa
    76201 gaggggactt cgatttgtgc gctacgcaga tgattgtgtg attacggtcg gaagcgaggc
    76261 agcctctaag cgtgtgatgt attcagtcag tcgttttatt gagaaacggc taggtttgaa
    76321 agtaaacatg accaagacta agattaccag accaagagag ttgaaatatc taggttttgg
    76381 gttctggaaa tcatcagatg gttggaaaag ccgtccacat caagatagtg ttcggagatt
    76441 taagcttaaa ttgaagaaac taacacatag gaaatggagt atagacctaa caagacgtat
    76501 tgagcaactg aatttgtcta ttcgaggatg gataaactat ttctcattgg gaaatatgaa
    76561 agtatagtcg ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag
    76621 caatggaaga agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg
    76681 atagcagata aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta
    76741 cttaaacgtg ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat
    76801 tattaccttg aacgacatgc gttaaaagtt agttgaaccg ctgtatgccg aacggcacgt
    76861 acggtggtgt gagaggggct agagattatc ccctactcga ttaactcccc tgaaatttat
    76921 tttaattatg caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca
    76981 gatatttttt tgactatcta aatctatcat tagaaaagct tagagcgcca aaggatttga
    77041 gcgtttttct gatttttaag actttttcca gtctcttttt cgattgaaga tgtaattatt
    77101 ctactaacta acttcttagt actagccaac aacgataatc ataattcctc ctaaaattag
    77161 gaataataaa ggcaatagtt tttgtttttt catgtaaaaa acctcacttt tgttttctgc
    77221 tattttatgc taaaatatta aaaatcaaat ttaattccaa agtttgtaac taaaggggga
    77281 gcgctacatg tctaattcat ttgtcaagtt gttagtctct caattatttg caaatttagc
    77341 agatattttc tttagagtaa caatcattgc taacatatac attatttcaa aatcagtaat
    77401 tgccacatca ctagttccta tcttaatagg aatatcctct tttgttgcga gtcttttagt
    77461 tccgttggtt actaaaaggt tagcgctaaa tagggtttta tctttatctc aatttggaaa
    77521 gactatatta ttggcgatac tggtaggaat gtttaccgta atgcaatccg tagcgccttt
    77581 ggtgacctat ctatttgttg ttgcaatttc catactagat ggttttgcag cacccgtttc
    77641 ctatgctatt gtgccacgct atgcgaccga tttgggtaag gctaattcag ccttatcaat
    77701 gactggtgaa gctgttcaat tgataggttg gggattaggt ggactcttgt ttgcaacaat
    77761 tggtctgtta cctaccacgt ttatcatttt agtcttgtat atcatttcta gctttctgat
    77821 gttatttctt cctaacgctg aagtggaggt gttagagtca gaaactaatc ttgaaatttt
    77881 gctcaaaggt tggaagttag ttgctagaaa tcctagatta agactttttg tatcagcaaa
    77941 tttattggaa attttttcaa atacgatttg ggtttcttcc attatacttg tttttgtaac
    78001 ggagttatta aataaaacgg aaagttactg gggatattct aatacagcat actctattgg
    78061 tattataatt agtggcttaa ttgcttttag gctatctgaa aagttccttg ctgctaaatg
    78121 ggaaagtatt ctttttcttc ttgtagctat ggcaatagtg acactgacta ttctatattt
    78181 tccaaacgca cagatgtttt tattattttc agctttagtt ggtatgttat cgcaactaaa
    78241 agaagttcct gaaagtgtat ttcttcagga aacagtagag gaaaatcatt tagttaatgt
    78301 ctattccgtt cttgaagtga tttctacatt agcattttca gtatttgttt tgctaatgag
    78361 ctatattact gagagttttg gtattagcat cagtttttgg ctatcagcca tttgtctgat
    78421 gatagaagct attttaattt atatcagacg agattatttt aaatgagaga gtggttaaaa
    78481 agtctttaaa aatcagaaaa gcgcatagta tcaggtgttg aaaaaacttg atattgtgtg
    78541 ttttattatg ggaagattta cttcattgtc tcctgaaatg gagttttgaa gcaggatcac
    78601 tctatttgaa aatatacata gaaaaactgt ataatcctta aaataagctg aaatctattg
    78661 gaaacatacg gtaaacaatt gaaaagatac tatataaagt ggtacaatgg tagaaaaata
    78721 agctagtaag aatcactctt attttagcga aaaattacag aaatgaatgg tttttcttga
    78781 tgaaacagag aaaagaattg tacctctttc ttggtcggac agccttgtat tttcttatct
    78841 ttctagggct gctttacttc tttagctatc ttggtcaggg tcaaggaagc tttatctata
    78901 atgaatttta acttgaagga gaatccctat tgtgtcaaat aaaccaatag cagatatgat
    78961 tgaaaccatt gagcattttg ctcagacaca gcctagctat cctgtctata atgttttggg
    79021 gcaggaacac acttatggcg atttaaaggc tgattcggat agtttggctg cagtcattga
    79081 ccaactaggc ttgcctgaga agtctcctgt ggttgttttt ggtggccaag aatatgaaat
    79141 gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc tacattccaa ttgatagcca
    79201 ttcggccttg gagcgagttt cagctatttt agaagtagca gagccaagct tgattattgc
    79261 catttcagcc tttcccttgg agcaggtttc tacaccaatg ataaatctag ctcaggttca
    79321 agaagccttt gcccaaggga acaactatga aatcacgcat ccagtcaagg gagatgataa
    79381 ttactacatt atctttactt ctggtacgac tggtaagcct aagggagtgc agatttcaca
    79441 tgataatctc ctcagcttta caaactggat gattacggat aaggaatttg cgacaccgag
    79501 tcgtccgcaa atgctggcac agccacctta ttcttttgac ttgtctgtca tgtattgggc
    79561 accgaccttg gcacttggtg gtacgctttt cactcttcct tcagtcatca ctcaggactt
    79621 taagcaactc tttgcggcta tcttttcatt gccaatcgct atctggacat caacaccatc
    79681 ctttgcagat atggccatgt tgtctgaata cttcaacagt gagaaaatgc ctggaatcac
    79741 gcatttctac tttgatggtg aagaattgac ggtcaaaaca gctcaaaaac tgcgcgagcg
    79801 tttcccaaat gcccgtatca tcaatgctta cggcccaaca gaagcgacag tagctctgtc
    79861 agcagttgcc gtgacagacg agatgttagc gactctcaaa cgcctaccaa tcggctatac
    79921 caaggctgat tctccaacct ttatcattga cgaggaagga aataaactgc caaatggcga
    79981 acagggagaa atcattgttt ctgggccagc tgtttcaaaa ggttatatga aaaatcctga
    80041 aaaaacagca gaagccttct ttgagtttga aggtctgcca gcctatcaca caggcgatgt
    80101 gggaaccatg acagatgagg gcttgcttct ctacggcgga cgcatggacc tccagattaa
    80161 gttcaacggt taccgcattg agttagaaga tgtctctcaa aacctaaaca agtctcgctt
    80221 tatcgaatct gctgtcgcag taccgcgcta taacaaggac cacaaggtac aaaatctatt
    80281 ggcttatgtc atcttaaaag acggtgttcg tgagcagttt gagcgagata tcgatattac
    80341 caaggccatc aaggaagacc tgacagacat catgatgtcc tatatgatgc catctaaatt
    80401 cctttaccga gacagtttgc cactaactcc aaatggaaag attgacatca aaggattgat
    80461 taacgaggtg aataagagat gatggagttt tttcaacagc ttcctcattt agagccatat
    80521 ggcaatcctc agtattttgt ttatgtgatt gctgcaacct tgcccatctt tataggcctc
    80581 tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa gtctcttctt tattgtcacc
    80641 atgttggtgg gtggaaagac caatcaacta gctgccttgg gtatttacct ttgctgggaa
    80701 atattgctcc tgcttttcta caagcattat cgaaaaagca aggatggcaa gtgggtcttc
    80761 tacttagtta gttttctgtc cctacttccg attatctttg tcaaggtgca accagctatc
    80821 aatggaacgc agtctttgct tgggttcttg ggaatttctt acctgacctt tcgttcggtt
    80881 gggattatca tcgagctgag agatggagtg attaaggatt ttaccctctg ggaattcctc
    80941 cgtttccttc tcttcatgcc aactttctcg agtggtccaa tcgatcgctt taagcgattt
    81001 aatgaaaatt atcaggccat tcctgagcga gatgagttga tggatatgct ggatgaatct
    81061 gtccgctata tcatgcgggg ctttttgtat aagtttatcc tagctcatgt tgtaggagag
    81121 accttactac ctcctctgaa gaatttagcc ttgcagtcag gtggcttctt taatctctat
    81181 gccttggcag ttatgtatac ttttggtctg gagctcttct ttgactttgc aggttattct
    81241 atgtttgctt tggccatctc aaacttgatg ggaatccgta gccctatcaa ctttaacaag
    81301 ccctttttat caagggattt aaaggagttt tggaatcgct ggcatatgag tctgtccttc
    81361 tggttccgtg actttgtctt tatgcgaatg gtgatggtgt taaccagaaa gaaagtcttt
    81421 aaaaatcgta atgtaacctc aagcatggcc tacattgtaa atatgctgat tatgggattt
    81481 tggcatggcg tgacctggta ctatatcgcc tatggactct ttcatggatt aggcttggtc
    81541 atcaatgatg cctgggttcg caagaaaaaa acgctcaata aggaacggaa aaaagcaggg
    81601 aaggctgccc tacctgagaa tcgctggatt cagttgcttg gtatggttgt cactttccat
    81661 gttgtcatgt tgtcattctt aatcttttct ggattcttga ataatctatg gtttaaaaaa
    81721 taaaaggaaa taaaatatgg atatcaaatc agaagttatc gaaattattg atgagttgtt
    81781 tatggaagat gtttctgaca tgatggatga agatcttttt gatgcaggtg tcttggatag
    81841 tatgggaacg gttgagttga ttgtggagat tgagaaccgt tttgacattc gtgtccctgt
    81901 aacagagttt ggtcgtgacg actggaatac agctaataaa atcatagctg gtattgtgga
    81961 gctacaaaat gcttaaacgc ttatggatga tcttcggacc ggtcttgata gctggtttgt
    82021 tggtttttct gctcattttc ttttatccta ctgagatgca tcataatcta ggagctgaaa
    82081 agcgttcagc agtggctact actatcgata gttttaagga gcgaagtcaa aaagtcagag
    82141 cactatctga tccaaatgtg cgttttgttc ccttctttgg ctctagtgaa tggcttcgtt
    82201 ttgacggtgc tcatcctgcg gtattagctg agaaatacaa tcgttcctac cgtccttatc
    82261 ttttaggaca ggggggagct gcatcgctta accaatattt tggaatgcaa cagatgttac
    82321 cacagctgga gaataaacaa gttgtgtatg ttatctcacc tcagtggttc agtaaaaatg
    82381 gctatgatcc agcagccttc cagcagtatt ttaatggaga ccagttgact agttttctga
    82441 aacatcaatc tggggatcag gctagtcaat atgcagcgac tcgcttactg caacagttcc
    82501 caaacgtagc tatgaaggac ctggttcaga agttggcaag taaaggagaa ttgtcgacag
    82561 cagacaatga aatgattgaa ttattggctc gttttaatga acgccaagcc tccttttttg
    82621 gtcagttttc ggttagaggc tatgttaact acgataagca tgtagctaag tatttaaaaa
    82681 tcttgccaga ccagttttct tatcaagcaa tagaagatgt tgtcaaagca gatgctgaaa
    82741 aaaatacttc caataatgag atgggaatgg aaaattattt ctataatgag cagatcaaga
    82801 aggatttgaa gaaattaaag gattctcaga aaagctttac ctatctcaag tcgccagagt
    82861 ataatgactt gcagttggtt ttaacacagt tttctaaatc taaggtaaac ccgattttta
    82921 tcattccacc tgttaataaa aaatggatgg actatgctgg tctacgagag gatatgtacc
    82981 aacaaacggt gcagaagatt cgctaccagt tagaaagtca aggttttacc aatatagcag
    83041 atttttctaa ggacggcggg gagcctttct ttatgaagga caccattcac cttggttggt
    83101 tgggttggtt ggcttttgac aaggcagttg atcctttcct atccaatccc acaccagctc
    83161 cgacttacca tctgaatgag cgctttttca gcaaagattg ggcgacttat gatggagatg
    83221 tcaaagaatt tcaatagata atataatata gaagagttca agaatgaaac tagttttcac
    83281 gttttttctt gactcttttt ttgcttgtga tataattaac tggtaaacaa aatgtcaaag
    83341 aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa aggagtcaga tatgagacag
    83401 ctagcaaagg atatcaatgc ttttttgaat gaggtgattt tgcaggcgga aaatcagcat
    83461 gaaatcctaa taggtcattg cactagcgag gtggccctga ccaatactca ggagcatatc
    83521 cttatgctct tgtcagagga atctttaaca aattcagaat tggcccgtcg tctcaatgtc
    83581 agtcaggcgg cagttaccaa ggccattaag tctttggtca aggaagggat gttggaaaca
    83641 tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt tgactgactt ggctcgtcca
    83701 atcgctgagg agcaccacca tcaccatgag catacacttt taacctatga acaagtggcg
    83761 actcagttta ctccaaatga acaaaaagtg attcagcggt ttttgactgc tttagtagga
    83821 gaaatcaaat aatgagatat attacggtag aggatttgtc cttctattat gataaggagc
    83881 ctgttcttga acatatcaat tattgtgttg atagtgggga atttgttacc ttgactgggg
    83941 aaaatggagc ggctaagacg acgctcatca aggctagtct tggaattctg caaccacgca
    84001 ttggaaaggt ggctatttca aagacaaata cgcaaggtaa gaaattgaga atagcctatc
    84061 ttcctcaaca aattgccagt tttaatgctg gttttccaag tacggtctat gaatttgtca
    84121 agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt gaatgctcat gatgaggagc
    84181 atatcaaggc tagtctggac tcagttggca tgtgggaaca tcgagacaaa cgcttggggt
    84241 ctctatctgg gggacaaaag cagcgagcgg taattgcgcg tatgtttgct tctgaccctg
    84301 atgtgtttat cctagacgag ccgacaacgg ggatggatgc aggaagtaaa aatgaatttt
    84361 acgaactcat gcaccacagc gcccatcatc atggcaaggc tgttttgatg attacccatg
    84421 accctgaaga agttaaggat tatgcggatc gcaatattca tctagtccgt aaccaagact
    84481 cgccatggcg ttgtttcaat gttcatgaga atggccagga ggtgggccat gcttagttta
    84541 ttatcttacg actttataca gcgcgccttt ttggcggtta ttgctatgag tcttttctca
    84601 ccggtattgg gaaccttcct catcttgcgt cgtcagagtt tgatgagtga tacccttagc
    84661 cacgtctcac tttcaggtgt agcctttggt ctggttttgg ggatttctcc aactgtttct
    84721 actattgcca ttgtcttgat tgcggcggtc tttctggagt atctccgtac ggtttacaag
    84781 agctttatgg aaatcgggac agctatcctc atgtcaacag gtctggctgt ttctctgatt
    84841 gtcatgagca agggtaaaag ctcgagttca atgagtttgg accaatatct ctttggttcg
    84901 atcgtgacta tcagtgaaga acaggtcatt tccctctttg tcattgcggc ggttgttttg
    84961 attttgacct ttctctttct tcgtcctatg tatatcttaa cttttgacga agatacggcc
    85021 tttgtggatg gcttgccagt tcgtaccatg tccattcttt ttaacatggt gacaggggtg
    85081 gctattgccc ttatgattcc tgcagcagga gctcttctgg tatcgaccat tatggtcttg
    85141 ccagctagta ttgccctgcg tctggggaaa aactttaaat cggttatgct gcttgccagt
    85201 gcgattggct ttttgggaat ggtagcagga ctttacattt cctactatgc agaaacacct
    85261 gcaagtgcaa gtattaccat tatttttgta actgtcttta tactaatcag tttagtaaga
    85321 cgttttatca aataggagac gaacgtgaaa aaaattagct tattactagc cagtctatgt
    85381 gccttgtttt tagtggcttg ttccaatcaa aaacaggcag atggtaaact caatatcgtg
    85441 acaacctttt accctgtcta tgaatttacc aagcaagtcg caggagatac ggctaatgta
    85501 gaactcctaa tcggtgctgg gacagaacct catgaatacg aaccatctgc caaggcagtt
    85561 gccaaaatcc aagatgcaga taccttcgtt tatgaaaatg aaaacatgga aacatgggta
    85621 cctaaattgc tagatacctt ggataagaaa aaagtgaaaa ccatcaaggc gacaggcgat
    85681 atgttgctct tgccaggtgg cgaggaagaa gagggagacc atgaccatgg agaagaaggt
    85741 catcaccatg agtttgaccc ccatgtttgg ttatcaccag ttcgtgccat taaactagta
    85801 gagcacatcc gcgacagctt gtcagcagat tatcctgata aaaaagagac ctttgagaag
    85861 aatgcagctg cctatatcga aaaattgcaa gccttggata aggcttacgc agaaggcttg
    85921 tctcaagcaa aacaaaagag ctttgtgact caacacgcag cctttaacta tcttgccttg
    85981 gactatggac tcaaacaagt cgcaatctca ggactttctc cagatgcaga gccatcagct
    86041 gctcgcttgg cagaattgac agagtatgtc aagaaaaata aaatcgccta tatctatttt
    86101 gaagaaaatg cctcacaagc ccttgctaac acactttcaa aagaagcagg tgtcaaaact
    86161 gatgtcctca atcctttaga aagtctgaca gaagaggaca ccaaggctgg agaaaactac
    86221 atttccgtga tggagaaaaa cctcaaggct ttgaaacaaa caacagacca agaaggccca
    86281 gcaatcgaac ctgaaaaggc agaggatacc aagacagtcc aaaatggtta cttcgaggat
    86341 gcagctgtca aggaccgcac cttgagtgac tatgcaggta actggcaatc agtttaccct
    86401 ttccttgaag acggcacgtt tgaccaagtc tttgactaca aggctaagtt gactggtaag
    86461 atgacccagg ctgagtacaa ggcttactat acaaaaggct atcagacaga tgtgactaag
    86521 attaacatta ctgataatac tatggaattt gttcaaggtg gacaaagcaa gaaatacact
    86581 tacaagtatg tcggtaagaa aattttgact tacaagaaag gcaatcgtgg cgtgcgtttc
    86641 ctctttgaag ccacagatgc tgacgctgga caattcaaat atgttcagtt tagtgaccac
    86701 aatatcgccc cagttaaggc agaacatttc catatcttct ttggaggcac aagccaagaa
    86761 gccctctttg aagaaatgga caactggcca acctactacc cagataacct atctggccaa
    86821 gaaatcgccc aagaaatgtt ggcgcattga tgagaaatcg actagttcat aagagctagt
    86881 cggttttttg atactagatg gctaacttca ttatagacct ttcagaacta agggaacctg
    86941 aaaaaataaa taaaactctt gaaatatctg ggcttatatg ctagaatgta gttagtgtat
    87001 aaggttcatt agaacaccaa agcccctaac tagtgccata gttaagggct tttttgacgt
    87061 atcttagcga tttaacgggt gtttataggc tagtcagtcg gtctacttct taccatctag
    87121 ccatttgcag acgaaataca agataattcc agctataaca tctgctataa tagtaagagc
    87181 aagctctggt ataaggctca ttagtttcac ctcctctcac gaacccatag gaacgtaatc
    87241 ggtaaccgat gacaaaagta ttataccaca ctaaatttag atcatcaacc tcacttaatg
    87301 cttgaactat tgtagattat atgctaaaat gtggttaatt gataaggttc attagaacac
    87361 caaagcccct aactatggcc gtagttaagg gcttttttga cgtatcttag cgatttaacg
    87421 ggtgtttata ggctagtcag tcggtctact ccttactatc tagccatctg cagacgaaat
    87481 acaagataat tccagctata acatccgcta taatagtaag agcgagctct atgataaggc
    87541 tcattagttt cacctcctct cacgaaccca taggaacgta atcggtaacc gatgacaaaa
    87601 tagtatacca caatacattt agatcatcaa ggtcatttaa ttcttgaaat atagggtcta
    87661 ggcgacaaag tctttaaaat cagaaaaacg cataatatca ggtgtgcaaa aacttgatac
    87721 tatgcgtttt attgtgggaa ggtttactcc attttctcct gaaattgagt ttttgtccag
    87781 cctctgtttt tagggttgct aagaaaataa tgtcatgtgg tgaatatttg taaatcagtc
    87841 agcagacaga acgatactct tcgaaaatct cttcacatca tgtcagcttc gtctttccgt
    87901 gtccatgggg gacttgactt catcagtttt caaatctgta ctttgagcaa gctgagacta
    87961 gcttcctatt tgattttcat tgaatatcag aaacccattc tccatcaaat aattcgactg
    88021 cgtctaataa tttttgatct ggcacggtgt cagaaataaa ggttgtgtat ttggataggg
    88081 gattaatttt aaaaaatcca gtcttgtaaa atttagaact atcaatcagt aagatggttt
    88141 catgggcttt gtcaataata ttcttttttg aaatagcttg gctgagagaa gcttcataaa
    88201 catattggtc atcaatacct cttgctgaac aaaatgctaa atcgatatta aaatgatcta
    88261 ataaagaatt ttccttatca tagttgacca cggaacagga ttgatgtttg acctcgccag
    88321 atgtgataaa gattttggag ctatctttaa cagtttcaga tagggtttgt gcagtatgta
    88381 aaccatttgt aaaaataatc aaattatcaa gttcagaaag atagggacag agttcgtaga
    88441 cagtagtact ggaatccaga tagatacaca taccagaccg aataaagtct ttagcgagac
    88501 tagcgattag tcttttttgc ctagtacttt ctccttcccg tatttgatga gaaagttcaa
    88561 ttgtgttcat agaggacagg gtcacgtatc cgtgctttct tttgataaga ccttgatttt
    88621 ctaagaaaat taaatcacga cgtaaggtac ttgtgctgga gaaagtgatt tctgccagct
    88681 cttttacggc aattcttttt ttctttttaa taatttcaat caattcaagt acacgttcat
    88741 cttttatcat aagctcctcc taatttatca tttcaactat attatagcac aaattggagg
    88801 aatttgaatt atttttatga atattgggtt aacatttgaa cattattcaa gtaagcgttc
    88861 acatattgaa aaaataaaat gtggggatta taataaagtt aatcaaggac gaagagagaa
    88921 gaaaaatgga agcggtttta gcaatagatt taggtgcgac ttctggaaga gcaatcgttg
    88981 gttacctttc tgaaaataaa ctagtaatgg aagaaataaa tcgcttttct aatctaccta
    89041 ttagagtaaa agggcattta tcttgggata ttgactttct actagctaaa attcttgaaa
    89101 gtatccgctt ggctaatact agttacaaga ttttatctat cggtattgac acatggggag
    89161 ttgattttgg actgattgat aatgaaggta agctgttatc acaacctgtt cattatcgtg
    89221 atgaaagaac aaagggagtg ttaaaggaaa tatctgaaat gactgaatta gaaaaactgt
    89281 attcagagac aggaaatcag attatggaga taaatacctt gtttcaactc tttaaggcac
    89341 gtcaagaatc tcctgactct ttctataaga ccaataagat tcttttaatg ccagatttgt
    89401 ttaattatct cttgacaggt aagtttgcta cagaaaaaag cattgcttca acaactcaat
    89461 tatttgatcc taggagtcaa aattggaatc agaatatctt aaaactattt gaattggatt
    89521 catctttact tcctgagatt gtttcagagg gaaatgttct tggaaggata aaaaaggagt
    89581 atggtttagg cgatattcct gttgtgaatg tttgtagtca tgatacagca agtgcgattg
    89641 tctcagtacc taagacagaa ggtagtttat ttatttcatc aggtacttgg tctttggttg
    89701 gagtggaact tacttcaccg attcttacta ccgaatcctt cagttatgga tttacaaatg
    89761 aagtcggtaa agatggagag attacatttc tgaagaattg tacagggttg tggatcatag
    89821 aggaactaag acgttcattt gaacgaagag ggaaagccta ttcttttgat gatattagga
    89881 caatggtgga gaaagaaaaa gaaaatcttc ctctgattga tactgaatca actgaatttg
    89941 caacagaatc tgatatgcac aagactttga cagaatatct agcttatcat catgaaacta
    90001 gagagtggac agatggacaa ctatttaaga ttgtttatga aagcctagct gaaacgtata
    90061 ggaaagcgat agagttatta gaagaactaa ctcataaggt ttataagagg atatatgtga
    90121 ttggaggagg tgctagagcc agttacttta accaaatgat tgctgataga actggtaaag
    90181 aggttcttac aggttcgact gagggtacag ctgtggggaa tattgttgtg cagctattga
    90241 gtcaaggtaa aataaacgag gatacagagt taaaggatat tatgacaaat attgctgata
    90301 caaaatatta ttatcctcag ctatcataaa caaaaataaa aaaaacggag gttttgtcat
    90361 gaacaaaaaa agtcttttga aatgcgctgt tatcgggtta gtagctacct ttggtttagc
    90421 agcttgtgga acatctaagg atgcaagcgg tggaagttct tctggtaaag aagtattaga
    90481 attttatcat gggtatcatc atagtgaaga tgaatggcct gtagcgaaga ctatgcgaga
    90541 tttatatgat aaatttgcag aagaacataa agatagtggt gtagaattta aaccaactcc
    90601 tgtaaatggt gatttgaagg atataatgaa taacaaggtt gctagtggtg aatttcctga
    90661 tgtgattgac ctagcaggta atgcagtatc attagctgcg attgaacaaa aacttgtttt
    90721 agatttgaaa ccatatatcg attcaaataa gcttgaaaaa aatgttggtt tgaactataa
    90781 gcaaaaccaa aaagatggaa aaatttatac agttcacgaa cagttattta caatgggttt
    90841 gtggtacaac aaggacatat ttgcaaaagc gggtgctaag acacctgatc agtggaatac
    90901 ttgggatgat ttcactcagg caatggcaag cattagaaaa caagatggag tgtatgcatt
    90961 tggtgctgga gaaccatcta ttcgcttgtt taatacagta ttaggaacca cagaaaatgg
    91021 acgtaaatta ttagataaac cattaacaaa agaaggaatt gaatctaaag aatttgcaga
    91081 tgctttgaaa atggttatga aagaaattca agctaatggt tctaagaatg ctggtggcga
    91141 tgccaatgct tattccaaag atttccaaga aggtaaatct gcagtattct ttaatggtgt
    91201 gtgggcttct ggtgagatgt ctaagaaccc aagtcttgca cctggaatct atcctgcagg
    91261 tgtagcaatt agttcttctg gaggtggtat cactatctca agtaagatgt ctgaagctaa
    91321 acaaaaacta gctcttgagt ttttgaaata tatgactagc gatgatgtac aaaaagtaat
    91381 ttttgaaaaa gtaggagcaa atccttctaa tgaaaatgta aatgtaaaag aactttcaga
    91441 aaagagttca gaagctacta ctaaaatttt aggacaagca atcactcaag ttaagaatgc
    91501 aaaagcagtt gttccaactg taagtgatgt ttggggtggc gatgtacaca cagctattat
    91561 caatgcattg acagaaagtg ctgctgaaaa tgtagatgtt gatcaaaaag taaaatctac
    91621 tcaagatgtg ttgaaatcat tgattggtta attgttttag ggagtgaaaa cgaagctcag
    91681 ttggcactgc caactgagct tgattttact tatatagttg aaaaaaggag tttgtttatg
    91741 gcacaaaaaa ttatgagcct acaaaatagg aagaatcaaa aaagacgatt tatcttttta
    91801 tttcttttgc caacgttgat ttgtttcttt ctattttatt tttattctgt agtaacaatc
    91861 tttttaactt catttgctaa atgggattat acaaatttaa acacccctga gtttcttgga
    91921 tttgataaat tatttgaaaa ttataggtat gtttttaaag aatacccatt ttttacagaa
    91981 gctctaatta attctgttcg ttgggctgta attggtgtta ttattcaagt tcctttagct
    92041 gtatctgttg caattacatt atctaagaaa ttaaaaggct ggaagatatc taggaatctt
    92101 tatattgtac caagtatcat ttctagtgct gctatgggct tgatttttct tcaaatctat
    92161 aatccaaact atggtgttgt taaccaaatt attcatctat ttaatccatc gtttaaagat
    92221 tcagtactgt tgactccagg attaaatata gtagctatga ctggcgctta tatcttcttt
    92281 gcaggagcat caaccattat gattcttggg caaatttttg ctattccaga agaagttcaa
    92341 gaagctgcta ttttagacaa tattactggt tggaggaaag agtggtatat tacgattccg
    92401 atgattaagg ggacaattaa aactgtttca attatggcag caacttcagg atttttgctc
    92461 tataacgaag tattcttttt gacaaatggt gctgcaggaa caaaaagtat cagttttgtt
    92521 attcgagaat tagcagtggc tagctcacga actcagtatg ctcgtgcaaa tacaattgga
    92581 gttatacaaa tcttaggtgg aatgttgatt atcgtttgta ttaatatttt attcagagaa
    92641 agaaaaagac tgaaaggtgg gaaatgatta tgaatacaca tataaatggt attagtaaaa
    92701 aaggcaaagt tcttatatat ggttatatgc tccttaccat tttaatttct attttcccta
    92761 ttgcgtggat ttttttatca tcattaaaag cagatcctat gaaaaatcca ggtattagtt
    92821 taccgactga ctttactctt gaaggttata taaatgtttt tacaaaactt catgttttta
    92881 cttacttttg gaatagcttt aaagtagtgt ctatatcagt tattattagc attgttatga
    92941 tctccatgtc ttcatatgtt attgctagga tggaatttag agggaagaag ttggtgactt
    93001 ctatgctgta ttctactcta tttattccag caacagctat gacttttcca gtttatagat
    93061 tagtaaatga gttggggatt tataataccc cagttgctct aattctggtc tactcttgta
    93121 gtggaattgc tatgagtttc tttattataa agaactattt tgaaattatt ccaaaagaat
    93181 tggaggaggc agcagagatt gatggtgcga catatgctca aactttttgg aaagtgatgt
    93241 tgccaattgc tagaccagga attttaacag cagcagtact tgcctttatt aataactgga
    93301 atgaatatta ttgggcatct atgttggtga ttgataaaaa tgaattaaca gtaccagcat
    93361 tactaggtca atttactaca agttttaata ctaattataa tggtctattt tcagctattg
    93421 ttgtaatcgt attaccacca atcattctat tcgcatttac aagtaaatac ttcattgaag
    93481 ctttaggagg aggagcagta aaaggatgaa acatacactt gaaactatca atagtagaac
    93541 tcagtggttt agagaagcaa gatttgggat gttcattcat tgggggttat attctattcc
    93601 aggaaaaggg gaatggattc gtagtcatca gaaattatct attgaagatt atgaaccata
    93661 ttttcgagct tttgatccta aggaatataa ccctagagaa tgggctaaac aagcaaaagc
    93721 tgcagggatg aagtatatgg ttttaacggc taaacatcat gatgggtttt gtttgtttga
    93781 ttcaaaattt acagattata aagcaacaaa tacacctgca ggtagagatt tagttaaaga
    93841 atttgtagat gctgttcgag ctgaaggttt aaaagtaggc ttatatttta gtttgattga
    93901 ctggcaccat cctgatttcc ctaaatatgc tgatctaaat catccaatga gaggaaatga
    93961 agcctatcga gatgagaaaa ttaactttga cagttatttg gagtatttgc acaatcaagt
    94021 taaagaaatt gtaactggtt atggtcagat tgacatatta tggtttgatt attcttatga
    94081 agacatggtg ggtgaaaaat ggggagcttc aaaattaata gacatggttc gtcattatca
    94141 gccaaacgtt atcgtagata atagattaga aacatcaggt gaaggattcg gaagtatcgt
    94201 tacagatgaa attacctctt acgctggaga ttttgttagt ccagagcaaa ttgttcctca
    94261 cgaaggtatt cgaaacttta aaggtgaacc tgttccttgg gaactttgtc taactatgaa
    94321 taacaattgg gcttataatc ctacagatta tctatataag tctagtcaaa ctttgataag
    94381 aaagttagtg gaatgtgtta gtaaaaacgg aaatatgatt cttaatgtag gcccagatgc
    94441 tttgggaaga attaatgatt caagtaagaa aatattagat aattttcatc gatggatgtc
    94501 tcgaaatggt gaggcaattt atggatgtag tggagatgaa aatttaccaa aaccagattg
    94561 gggatactat actcgtaatg gaaatacggt ttatgctcat gtatttgaac aacctatagg
    94621 tcctttagct cttcttggta ttagtaaaga aaacgtaaaa agaatgagct ttcttcatga
    94681 tggaagtgag gtgaaaattt cagaaagctg gacgaccaat gcctacaaag gaatttgttt
    94741 tgcacagttt ggagaagttc cacattttac ctatccatta ccagacttga ttgatagcgt
    94801 aatcaaaatt gagttgagag agtagtttat atgaaaattg aaaataaaaa tgtaagacgt
    94861 aatttctttt ggggagaggg tcgattttat actactgata tcgtaaacaa acgggcagga
    94921 gtaatgataa aaaatgtttc gaaagaggaa tttaccatta cactggagaa tggtataaga
    94981 ctttcttcaa atcatttttc agcaatcgtt agggaagagg gagatacgcg aattcaggtt
    95041 tcttttgttt gtccttccat tcgtttacgt ttaatctttg aatcgaggga tgatgttctt
    95101 tcgaagcaat tagttttaga atcatctact gaggttatta aatctgtaga ggtagagagt
    95161 tttgagtttg aaacagaaga caatattttc tatccgaaaa gacaagattg tattaaggaa
    95221 atggcgaatt tttccggtta ttatgtagaa ttgggacaac ctgtttatgc gaattcttta
    95281 ttcttaggaa tggaatttcc aatgtctgaa aacaaggtag atggtagaca ctatgtatca
    95341 agatattact tgggaactgt tgtaaatcaa gaaaagagtt tgtggtcttg tattattggg
    95401 ggagcatgct cttataaaaa agaagagatt caagaggcat tttttgaata tgttgaagga
    95461 atagctcaac ctagttattt ccgtaaacag tataattcct ggtatgacca tatgaccgat
    95521 attacagagg aaggtattct aaaaagtttt tctgagattc gagatggatt tgaaaatcat
    95581 ggagttcatt tagatgctta tgttgttgat gatggttgga caaactatca atcagtttgg
    95641 gaattcaatc ataaattccc aaatggtttg agaaatatta aacatcttgt aaatggattt
    95701 ggttcaagcc taggattgtg gattggtccc cgaggtggtt ataatgggac agaaatcatt
    95761 atgagtgatt ggttagaagc acatccagag ttaaatattg gatctaaaaa tttgatttca
    95821 aatgatgtaa acgtggctga ttttaactat ctcaatcaaa tgaagaaaaa gatgttggaa
    95881 tatcaaaaag aattcgatat cagctattgg aaaattgatg gttggttact tcaacctgac
    95941 aaacctgata agagtggacc gcacggtatg tataccatga cagcggttta tgagttctta
    96001 attcaactgt tgatagatct aagaaaggag agaggaggaa aagattgttg gttaaacttg
    96061 acttcttatg taaatcctag tccatggttt ttacagtggg tcaatagttt atggattcaa
    96121 atatctcaag atgtaggctt tacagagaat gcaggtaatg atatcaatcg tatgattact
    96181 taccgagata gtcagtatca agaatttttg gaaaaacgtg agatacagtt acctatgtgg
    96241 tcgctttata atcatgaacc aatctatgct gtcagtgcaa atacctggta catggatcat
    96301 caaatgtttg catcaatacc agattttgaa gcttatctat tatttatttc aacaagaggg
    96361 aatgcttttt gggagtttca ctattctttt gatatgtttg atgaagaacg ctggaaagcc
    96421 aatgctcgtg ccgtcaaatg gatagaggag aattatcaaa cactaaaata tagtaaaaaa
    96481 ataggaggaa gtcctgaaaa atttgaaatt tatggttata agtgtcacaa tcagaagact
    96541 tctactgaaa ttctctctct gagaaatcct gctcagatta aacaaaaaat aaaaatagag
    96601 aatctttcga tagagaattt taccagagta attggagatt ttactattca agaagatgag
    96661 atagaattgg caccgtactc tatcgtgata ctgaagaagt aaagaaaaaa ttgtgaggta
    96721 gagatgacga tttatattaa taaggacgag accgtttttc atttggcaat gaaagatagt
    96781 agttatattt ttagaatttt agaaaatggg gaacttcaac atctacattt tgggaaaagg
    96841 attcatgtca aggaaaatta taaccaattg atggcctatg aaaaaagagg atttgaagta
    96901 tctttttctg aagaatttga ggatattcaa cagtctatga tacaaaatga atattcttca
    96961 tatgggaaag gagattttcg gcatccagcc tttcaagttc aaggaatgaa tggtagtagg
    97021 ataacgacac taaaatatca aggttttgaa cttgaaaaag ggaaaaatcg tcttaactct
    97081 ctaccttcaa catttgatga tattggtcag tgtgcggaaa cattaacgat tattttaaca
    97141 gattccatat tagatttaac tgttagacta aattacacaa tttttccgga atacaatgtc
    97201 ttagttagaa atacggaatt tttaaataat agcaataata agttgactct tttgaaagca
    97261 atgagcttac agctagatct acctgatagt caatatgact ttattcaatt ttctggagca
    97321 tggctgaggg aacgtcagtt atatagaact tcgcttagac caggtattca agcaatagat
    97381 agcttgagat actcatcaag tcctcagcaa aatcctttct ttatgctatc aaggagggaa
    97441 actacagagc atagtggtga gatttatggt tttaacttta tctattctgg aaattttcaa
    97501 aatatgattg aagttgacca ttttgacacc gctagagtaa cggtaggaat aaatccagta
    97561 gaatttcgtt ttttattaaa tcctgccgaa agttttgtga caccagaagc aattgtgatc
    97621 tattctgatc aagggatgaa tcagatgagc caacaactat cagattttta tcgacatcat
    97681 ttagttaatc ctaatttttc tcaagctagt cgtcctataa tactcaatag ttgggaaaca
    97741 ttttattttg acttgagtac agaaaaaatt ttagatttag caaaggctgc taaagattta
    97801 gggatagaat tatttgtact ggatgatggt tggtttggtc ataggaaaga tgacaaaagt
    97861 tctctgggtg attgggtaac agatagaagt cgtcttcctg aaggtattgg atttcttgca
    97921 gatgaaattc acaaaatagg tttacaattt ggtttgtggt ttgagcctga aatgatttct
    97981 attgatagtg atttgtacaa gaatcatgcc gattggacta tccatttgtt agacagagag
    98041 aagtcagtag gaagaaatca atatgtgttg gatttgacga gacaggaagt tgttgattat
    98101 ctttttgatt ctatttctaa aatcataatc aaaacaaatc tggattatat caaatgggat
    98161 atgaatcgtc atataacaga tatttatagt attgaacttg attctgaaca gcagatggaa
    98221 tttggtcatc gatatatctt aggtctttat cagttattag atcgtttaat aactaagttc
    98281 ccttcagttc tatttgaatc ttgttcttca ggtggtggac gttttgattt aggacttatg
    98341 tattatgcac cgcaagcgtg gacgagtgat gatacggacc cgatagaaag attgaaaatt
    98401 cagcatggaa cttcttatgg atattctcca tcaatgatga cagcccatgt ttctatttct
    98461 ccaaatgaac aaagtggaag acaaacgagt ttggacacta ggacaaatgt agcttatttt
    98521 agttctttcg gttatgaatt agatgttacg agattgtcgg tagaagaaaa agaacaagtg
    98581 agagaacaaa ttcagtttta taaaaaatat tgttcattgt ttcaatatgg ggatttctat
    98641 aggataaaca gtccttttag ttgtgattct gctagttggc aagttgtttc aaaagataaa
    98701 tgccaatcga ttttattgta tgctcaattg aatagtaagt tgaatccagg ttatacaaga
    98761 gtttatttta gtggtttaga taaagataaa tgctattccg tctctggatt tgatgagttc
    98821 ttttatggag atgaattaat gaatgctgga ataaaagtaa gtttaagtaa tttagcactt
    98881 tgtgttccag aatatcttac aaaattattt gttattgagg aagttgtatg taaatattga
    98941 ggaaataaaa atggaaagta aaaaaatagc aaaacagatt ttaatagcta cggctgtttt
    99001 aacaagtttt ttaggaagta atttggttta tgcagatgta gttcaaagta attctaataa
    99061 cagagctagt actgaaactg ctagagtaac agggaataac ttagaaaaac ttattactaa
    99121 aggtaaagaa attgataaag agatgacata tctttcagat atggattggt cttctgcaac
    99181 tcatggtgat atagataaaa caaaaacagt acaaaaagat gctccattta caacaggaaa
    99241 taaaggagag catactaaga tttcattgct cacttctgat gataaagtta agtattttga
    99301 taaaggaata ggaatagtcg cagattctcc atcagtaatc agctatgata ttagcggtca
    99361 agggtttgaa aaatttgaaa cttatatagg aattgatcaa agtgctaata gttctagatc
    99421 agaccatgca gtagtggata gaatagaaat agaaattgat ggaaaggttg tctattctag
    99481 tagtgtaact aatccagaag gattcagata taatacccag gcacaattta ttagtgtgac
    99541 aattccacaa aacgctaaaa aaatatcctt aaaatcattc gcaggagaac atacatgggg
    99601 tgatgaagtt gtatttgctg atgctaaact tattaaaact gttagtactc aaactataac
    99661 tccagatctt cttaataaag gaattaatgg aggagtatat ctttctgatt tagaatgggt
    99721 tgatgctact catggtgatg acgataaatc aaaaacagtt cagaaagata aaccgtttac
    99781 acctggtaat aacgggtcta ataataaaat aaaattacta attgacggta aggaagtcga
    99841 atttaataag ggattgggaa ctgtagcaag taacccgtct agtataaaat atgatgtttc
    99901 gggtgctaat gttacaagat ttatttccta tgtcggaatt gataggagtg caaatcattt
    99961 aaattcagat tacgcagata ttcaaaaatt tgaagttgtt gcggatggta aagtcattta
   100021 ctcatcagat tcaaaatatc caaaaggaat taagtatgat acatcggcat ttctggttga
   100081 tgttgaaatt cccaaagata cacagacaat agaacttaaa tcatattcag ggaaacatac
   100141 atgggctgac gaattggttt taggtggagc cttgtttatg gcaaatggta aatttaagaa
   100201 tcctaatgat tggtcagaag ttgataaacg tcgtgaaatt aataatgaac atccgttact
   100261 tatgatgcct ttatatgcta acggagaaga gtttaaccaa gggaaatata ctttttgggg
   100321 aggagataca ttaacaggta agtgggagaa tataccagat gacttaaaac catatactgt
   100381 tatacagtta catccagatg atcttcctaa aagagatgga gctgctagag atttttatga
   100441 acatatgtta gaagaagcag cgaaatatgt aaatcctaag actggaaaaa atgaaccaat
   100501 tccagttatt ctgacggttt acactgctgg taatatgcct tattatactt cggcacattg
   100561 gttaagtacc agctggattg ataaaatgta tcaaaaatat ccaaatttgc atggtatttt
   100621 cagtacagag aattattgga tttgggcaaa tgatattgaa aataaggcgg cagattactt
   100681 aaaagtatca gctaaaaatg gaggatattt tatatgggct gaacaaaata atggttctgc
   100741 aatagaaaaa gcatttggaa aaaacggtaa gatagcattt cagaaatctg ttgataagta
   100801 ctggaagaac cttattttca tgttcaaaaa tacacctgct gctgagggaa atgattcaac
   100861 tacagaaagt tatatgaagg gactttggct ttcaaatcat acttatcaat ggggtggttt
   100921 gatggatact tggaagtggt atgagacagg taaatggaaa ctgtttgcaa gtggtaatat
   100981 cggaaaaagt caaggagata gacaatggtt gactgaacca gagtctatgc taggagaaga
   101041 agctttaggg atttacctta atggaggtgt agtttataat tttgaacacc cagcttatac
   101101 ctatggtgta aataataaag aaagcttact ctttagtgaa gtaataaaag aattttttag
   101161 atatgtaata gcgcatccag caccatccaa agaaaaggta cttgaggata caaaagtatt
   101221 catacatgga gactattcaa ataaaggaaa tggtaagttc tttgtaaacg taaatactga
   101281 tagagaacaa actccattat acatgactgg tcgttataat gttattccag ctattccagg
   101341 tgttttaaaa acagataaat tgaaagagtc tgtttcgggt agccatattc agattaagga
   101401 aatcacttct ccagaattta gctctactca ggctagaaaa gaatacttaa ataagctgta
   101461 tcctatgaat tatgaaggag atatctttgc tcagaaatta gataatagat ggtttgtcta
   101521 taattacaag gtaaatgaga atgttaaaca gactgggaaa ttaaaattta attctttaga
   101581 aatggatgtt gaatttgaac ctcataccta tggtattttt gagagaataa gtaatggatt
   101641 gaaagtgaat ttaaataatt ttagaacaaa taaagattca ctatggtcta atgctcaaga
   101701 tgcaaatcag gcaaagaaac taccacaatt gaccaagaaa ggtgccatta agtggattga
   101761 agaacattat atcaaagata ctcagtttgg agagaaaagg gttacaaaga tagtattaag
   101821 aggtatagat aaacttccta ctattcattc attatcagga acaaataatt cctatgatca
   101881 gccatctctc aattttgatc agaaaaatca tatggttact attaccatta acagtaacgg
   101941 aaatcttgaa ttcgaacttc atttttagaa aggagtgagt ttatgtctca agatgaaaaa
   102001 ttaattcgtg aacagatttg tgatgtttgt cataagatgt ggcaacttgg ttgggttgct
   102061 gctaacgatg ggaatgtatc tgttcgatta gatgaggata ccattcttgc aacacctact
   102121 ggtatcagca aaagttttat tacaccagaa aagctggtga agttaaatct caaaggagag
   102181 attttagaag cagaaggtga ttaccggccc tctagtgaaa ttaaaatgca cattcggtgc
   102241 tacgaagaac gtgaggatgt tcgttcagtt gttcacgcgc atccaccgat tgcaacagga
   102301 tttgctcttg cacacattcc tttagatact tattcactaa ttgagagcgc gattgtggta
   102361 ggggcaattc ctataacgcc atttggagtt ccgtctacaa tggaagtgcc agaagcaatt
   102421 acaccttatc tgcccgatca tgatgtcatg ctattagaaa atcatggagc tctgactgtc
   102481 ggaagcgatg taattacagc atactaccgt atggaaactt tagaattagt cgcaaagaca
   102541 accttccacg gaagaatgtt actttctaca aagggcattg aggagcaaga aattgctcgt
   102601 ccgactttag aacgtctatt ctcaatgcga gaaaattata aggttacagg tcgtcaccca
   102661 ggctaccgta aatataatgg cgatggtagt atgaaagaaa cagaaaaata agaggaaaat
   102721 agtatgattc aacatccacg tattgggatt cgtccgacta ttgatggtcg tcgtcaaggt
   102781 gtacgcgaat cacttgaagt acaaacaatg aacatggcta aaagtgtggc agatttgatt
   102841 tcaagcacat tgaaatatcc agatggggaa cctgtggaat gcgtgatttc tccatctact
   102901 attggccgtg ttccagaggc tgcagcttcc catgagttgt ttaaaaaatc aaatgtttgc
   102961 gcaacaatta cagttacacc atgctggtgt tatggtagtg aaactatgga tatgtctcca
   103021 gatattcctc atgctatttg gggatttaat gggacagaac gcccaggagc tgtctatctt
   103081 gcagctgtac tagcttcaca tgctcaaaaa gggattccag cctttgggat ttatggtaga
   103141 gatgttcagg aagctaatga tacagatatt ccagaagatg tcaaagaaaa acttttacgt
   103201 tatgcgcgtg cagctcttgc aactggcttg atgagagaca ctgcttacct atcaatgggt
   103261 agtgtttcga tggggattgg cggttctatt gtaaatccag atttcttcca agaatactta
   103321 ggaatgcgaa atgaatcggt agatatgacg gagttcacgc gccgtatgga ccgtggtatt
   103381 tatgacccag aagagttcga acgtgctatg gtttgggtaa aagaacatat caaagaaggg
   103441 gttgaccgaa atcgtgagga tttgattctt tctaaagaag agaaagaaaa acaatgggaa
   103501 tttgttatta agatgttcat gattggacgt gacttaatgg ttggtaaccc aagacttgct
   103561 gaacttggtt ttgaggaaga agcggttggt caccatgctt tagtagctgg tttccaaggt
   103621 caacgtcagt ggacagacca ttttccaaat ggagatttta tggaaacttt cctcaatact
   103681 cagtttgact ggaatggtat tcgaaaacca tttgtatttg cgacagagaa tgattcacta
   103741 aatggtgtgt ctatgctctt taattatcta ttaacaaata ctccacaaat ctttgctgat
   103801 gtgcgtactt attggagccc agaggctgtt aaacgtgtaa cgggacatac tttagagggt
   103861 cgtgctgcag ctggcttctt acatctaatc aactctggtt cttgtacatt ggatggtaca
   103921 ggtcaagcta ctcgagatgg caaacctgtt atgaaaccat tctgggagtt ggaagaaagt
   103981 gaagtgcagg ctatgcttga aaatacagac ttcccaccag caaaccgcga atacttccgt
   104041 ggaggaggat tctcaactcg tttcttgacg aagggggata tgccagtaac aatggtacgt
   104101 ctcaatcttc taaaaggggt tggtccagtg ctacaaattg cagaaggtta tacacttgaa
   104161 cttcctgaag atgttcacca tactttagat aatcgtacag atccaggatg gccaactact
   104221 tggtttgctc cacgtttgac aggaaaaggt gctttcaagt ctgtctatga cgtcatgaat
   104281 aattggggag ctaatcacgg agccataaca tatggacaca ttggagcaga cttgattacc
   104341 ttggcttcta tgttgagaat tcctgtcaat atgcataatg tacctgagga agatatcttt
   104401 agacctaaaa attggtcctt atttggaaca gaagatctag aatcagcaga ctatcgtgca
   104461 tgtcagttgt tgggaccact acataaataa aacttgttta tataggaggt gaacttacgt
   104521 ccctcctatc cttttaaaaa gatttgttaa acaattcaca aataattgaa aacgaataca
   104581 aaaagtaata taatgatgtt aaatagatag cgcaaaggcg caggaggaaa attatatggc
   104641 tacattttat gttccggcag tcaaccttat tggtaaaggt gttgtaaatg aagtgggtcc
   104701 ttatatcaag gaacttggct ataaaaaggc acttttggtg acagataagt acatcgaagg
   104761 cagtgacatt ttacctaagg ttttaaaacc actggataca gaaggaatcg aatatgtcat
   104821 ctttagcgat gtagagccaa accctacttg taagaatgtc acagatgggg tagctgcttt
   104881 gcaagaacat ggatgtgatt ttatcatcag tcttggtggg ggttctccac aggatgcagc
   104941 tagttgtatt tctatcatgg ctacaaatgg tggaagacca caggattatg aagggcttca
   105001 taagtctgct aaaaaaggct tgccagttgt ggctatcaat acaacggcag gaacttctgc
   105061 agaaatcact attaactatg tgattactga tgaagaacgc aaggttaaga tggtaatggt
   105121 tgacaagaat agccttgctc ttatctctgt caatgacccg gaactcatgc tttccaaacc
   105181 tcaagccttg actgctgcta ctggtatgga tgctctgact cacgctgttg aagctttggt
   105241 aacacctggt gcttatgatg taaccaagaa actgtctatt ggtgctattg agcttatcaa
   105301 ggaatatctt cctcgtgctg tagaaaatgg acatgatatt gaagcgcgtg aaggtatggt
   105361 caatgccatc ttccttggtg gtatgagctt taataatgct ggtcttggtt atgttcactc
   105421 aatggctcac caactcggtg cagtatataa tttgccacat ggtgtttgct gtgccatgtt
   105481 gctaccagtt atagaacgtg aaaatgctaa acgtgtacca gaagctttcc gcaatgttgc
   105541 caaagccttg ggccttcatg tggaaggtaa atcagatcaa gagtgtgccg attatgcgat
   105601 tgctgagatt gagaagcttt ctgagacagt aggtattcct aagaaattga ctgaacttgg
   105661 tattgaagaa aaagatttcg actttgaata cctttctaag aatgccttga ttgatgcctg
   105721 cgcaccagga aatccattta tgccaacctt agaagaaacg attgcctttt ataaagagtt
   105781 attttagcaa gagattggac gacaatagga caattcacct ctaattattg acatttcagg
   105841 aaaaatcgca gtaaaaacgg cacagccttc tttaaatgtg ctataatact agaaaaatac
   105901 ttgtggaggt tccattatgg caatattttt catgattttt ctgattgttt gtgtgctcct
   105961 attggtgata gtcacactga gtacagttta tgtggttcgt cagcagtcgg tggcgattat
   106021 tgaacgcttt gggaaatacc aaaaggttgc taatagcggt attcatattc gcttgccttt
   106081 tgggattgac tcgattgcag cacggattca gttgcgcttg ttgcaaagtg atattgtggt
   106141 tgagactaag accaaggaca atgtgttcgt tatgatgaat gtagcgactc agtaccgtgt
   106201 caacgagcag agcgtgacag atgcttacta taaactcata cgtccagaat ctcagattaa
   106261 atcttatatc gaagatgctc ttcgctcttc tgttccaaaa ttaaccttgg atgaattgtt
   106321 tgagaaaaaa gatgagattg cccttgaagt tcaacaccaa gtagcagaag aaatgaccac
   106381 ttacggctac attatcgtga aaaccttgat taccaaggtc gaaccggatg cagaagttaa
   106441 gcaatccatg aatgaaatca atgcggcgca acgtaagcgg gtcgcagcac aagaattggc
   106501 ggaagctgac aagattaaaa ttgtcactgc agctgaagca gaagcagaaa aagaccgcct
   106561 tcatggtgtg gggattgccc aacaacgtaa ggcgattgtg gatggattgg cagagtctat
   106621 caccgaactt aaggaagcca atgttggcat gacagaagaa caaatcatgt ctatcctctt
   106681 gaccaaccag tatttggata ccttgaatac ctttgcctct aaaggaaatc aaactatctt
   106741 tttaccaaat actccaaatg gtgtggatga tatccgaaca caaatcttgt cagcccttcg
   106801 cgctgagaag aaataataga ctaatactct tcgaaaatct cttcaaacta cgtcagcgtc
   106861 gccttgccgt atagatgtta ctgactttgt cagttctatc tgcaacctca aaacagtgtt
   106921 ttgagctgac ttcgtcagtc ttatctacta ccgcaaaacg gtgttttgag caacctgtgg
   106981 ctagtttcct agtttgctat ttgattttca ttgagtacaa agagcttggc aacaggctct
   107041 ttttgtattg cgtttattaa gaaaaacaaa aaacatcgat atacatttaa ctaaaaatta
   107101 ttgtatgtta tctcccttaa ttaggaatga taagggaata actagaaaga tttgtgaata
   107161 caaactattt ctgatataca aaatatacag taataatgaa tgatgggaga tgagatgaaa
   107221 gaatttcaat ttgagagaaa gcagcgtttt tctttgagga aatatgcaat aggagcttgt
   107281 tcggtcttgc taggaacgag tttatttttt gctggtatgg gtgctcagcc tgtacaggat
   107341 acagaaacga gttcagcact aatttcaagt cattatttgg atgagcagga tttatctgaa
   107401 aagctgaaat ctgagttgca atggtttgaa ttagaaaaca agcttttgaa cttatgggag
   107461 cattaggtta ctatgaagga tttgttcctt atgtttcaaa tcaatacaaa aaccaagctg
   107521 aagaagaagg caaaccgcta tctgataaat atattttcga aaaaatctta ggaaaaacat
   107581 atgcagcctt caaaaaaaga tcaaattaat gagcgtgtcg agaaattagg taagttaaaa
   107641 cctattacaa taaattacaa cggaaaatca gaagtaattg atagtaaaga aaaattacaa
   107701 gagcttatga ataaagccgt taaagacgaa gtggctcaaa tatagtaaaa tgaaataaga
   107761 acaggacaaa tcgatcagga cagtcaaatc gatttctaaa aatgttttag aagtagaggt
   107821 gtactattct agtttcaata tactataaaa tcaggcaata ccacggctaa aaagtttgag
   107881 tttatcgaaa caccagtgca aaaactgaaa aaagcgattt ataaagctca tctcaaagat
   107941 tcagatgact ttagaccaga aacatccaca caaatctttt tgaaagctgt ttgaagcttt
   108001 gtccttgctt tcttagttca tagatctgaa ctttatcttc ataattcaat ttcataataa
   108061 aacaccccaa aagttagatt tattctgtct aacttttggg gtgcagttca ttaatcggtc
   108121 gatttttttt ggtagaaaca gttgcctgat taagttgcaa gtcgatagac ggcttcggcg
   108181 taaatatcca tagcacggta caaatcttct agaacggcac attcatttgc ctgatgttct
   108241 gtctgcttcg ctcctgggaa taaggcgccg aaggctacac aatttggcat ggtgcgagca
   108301 aaagtggcac caccggatga aatagcagga ctgttatcgc cagtcttttc ttggtagatt
   108361 tgcatcagtg tgctaacgag tttactgtct tttgcgacgt atagaggcgc tagatagtca
   108421 aactcttcgt agcggagttg gtagttttgt gcacatcttg taagcaactc tactagttct
   108481 tccttgtcag ctaagacagg agtccgaatg tcaatacgga tttcagaacg ttcatgattg
   108541 atcatgagac ctgcgacatt aaaggatagg tgaccagaag gttcatctgc tatatcacca
   108601 aagatttgtc ttcctgtgcc gtcttgacct gcttgtgttg caagaaaact gagagcaggg
   108661 tgttcttgga gaggagcaag aatggtagct agtcggatga cagcattgat accttgacta
   108721 gcatccttag catgctttgg cactccgaga accgttacgg tttgttcagt ggattggtaa
   108781 tcataaccag cttctttgag accgttacaa acctgttcat agaggggacc ttggtagttg
   108841 gccttgtctg gtacaacgtt aaaggcgcct cctacttcaa gctctagttg atccgatcca
   108901 gggccatgaa gtttgacctg tagaagccct ttttcagcat aggtcagagg aaaagatgag
   108961 tcaggtgcaa agcccatact ggcctgttct tcgatggtat tgtagcgtgc catgcagcgc
   109021 cagagggttt cctcatcggt accaaagata aagcgtacgc gctttttgaa ctgaatacct
   109081 tggtccagca agctttttac tgcatagaga gctgcgagcg aagggccttt atcatcttgg
   109141 acaccacgtc cgaataccca gccgtctttg atagttgctt caaatggcgg tgtctgccaa
   109201 tctgcttcat cacctgatgg aacaacatcc aaatgacaga gaatgaccag aagctctgct
   109261 ccctgaccga tttctgcata tccgtaataa cctttagggt caagataggt agtgaaacct
   109321 atgtctcgac aaatctctaa agttttttct aggacatctt ggattgcttg tccaaaaggt
   109381 gttccatttt ctccttcatt gagtactgaa ggataggaaa tcaaggtttt taatgatata
   109441 agaaattcat ctttaacttg atttgttata tctattttca tggaatcacc tcactcacta
   109501 ttttatagga atggaaggaa ggttccaagg agaagaaggg cgatggtcac tacaataata
   109561 gcgactacga gtttgcccat gaatttccac caagtaccaa tgttgatacg tccaagtgca
   109621 agagctccta tcacaatacc agatgttggt gcaatcaagt tcaagacacc tgaagcagat
   109681 tggtaagcag tgataatcaa gctaggacgg acatttacaa attctccaag tggagccatg
   109741 atacccatag ttgcgctggc aagaccagat gaagatggga tcaagaatga cataggtaga
   109801 tagaagatat aagttacaac gataaagact tgtgaagata gaccgctcaa gccttcttta
   109861 ccccagttga ggattgtatc ggtaatcata ccgtcgttca tgataacttg aataccacga
   109921 gcaatcgcta cgatcaaggc aacactgagc aagtcagcag caccattcat gaaggaagag
   109981 ataatcttat cttctttaag accataaata acaccaatca ggatacccat aaaggcaaag
   110041 agcattgcgc cttctgggaa gtaccaagta cctagtgcag aagtagatga accgacaata
   110101 ttaccaataa ctggaagacc agtcaaccaa gcattaaagt catcaaaaat ggtaacgcca
   110161 aggtctgtcc atggaatgaa gctcaatacc atcaagatga atgtcaacac aaataagaag
   110221 agaactgatt tttgtttgct gctaagtgta gattctacag atgaagattc ttctacgtta
   110281 aagtgtttca aatcttcttt gcgagtacta taaaccagtg acttagtcgg atctttttga
   110341 atcttatccg cataacggta aacaaaccaa gtactaagag cagtcaaggt aacccagaag
   110401 atcagacgaa gtacgatacc gtcccctgta ccaactcccg cagtcgctga agcaatacct
   110461 gtcgcaaatg gattcagagt agatgccaaa cagccgattt gagaaccgag caaaataatt
   110521 gcaacaccag tcaggctatc aaaaccaacg gccatcataa ctggcacaag gagtggatag
   110581 aaggccattg tttcttcccc cataccataa gttgtaccac cgagggcaaa caaaggcatc
   110641 agtaccaaaa ttaacatttt ttcgcggccc ttatacttct tcacgataga ggcaatccct
   110701 acgtcaagag caccagtttt gttgacaatg ccaaggaaac caccaaccat aaggatgaag
   110761 aaggctacat caatcgctgc gctcgtttct ttaatgagcg aaccttcctc tggatgagta
   110821 cctagcatag cccgaatcgg tgccatgagg acatcccaaa tcccttgtgg attttgaggc
   110881 tgagtctcgt aaataccttc tataaaggcc cccgcaggga taaaccaagt tagtactgcc
   110941 ataatagcaa tgattatcaa taatacggtg taagatgaag gcatcttaaa ccctttttta
   111001 gctttttcac tcatttgttt ttcctcctga tgtctaacaa agtgtaaaaa accaactact
   111061 ttcttaaata aacattcaag aaaacgcttt ctatttatat ttgttttacc atattaaagt
   111121 ctaaaaaact aatatctttt gaaatattgt acatgttttc aagaataatt tctaatttga
   111181 tataaagata ctagaaatag aatacatctt attagtaaaa caacttatcc tttttcaata
   111241 attgttccgc tttcagattc aatcaaggcg cctagatttt caagggaagt aataactgct
   111301 tttccttctg gacgaccatt gacaaaagcg atagctgctt ctacttttgg aagcatgcta
   111361 cctggtgcaa actgatcttg tttgatatat tcttccagct gggcaacatt cacatgttcc
   111421 aatttttcct ggtttggctt gttgtagtta acaaatacat aatctacacc tgtcaaaacg
   111481 atgaagaggt ctgcctcaac caattctgcc aaacgttggg aagcgaagtc tttatcaata
   111541 accgcttcga caccagtcaa atgtccattg ttttctttga cgacgggaat accgccacca
   111601 cctgcagcta cgacgacttg accactattt aaaagagtac ggatggtttc aatttctttg
   111661 atgtcaacag gttttggtga ggcaacgacc ttacgccagc cacggccagc atcttccttg
   111721 aaagtcgctc cgctcttttc ggcttctgct tttgcttctt cttctgaata gaaaggaccg
   111781 attggtttac tcaaattaac aaaagctgga tcatttttat ctacgacaac ttgcgttaca
   111841 acagaggcaa catttttttc gatgccttca tccaagagag cattttgcaa agcatttttc
   111901 aaccagaaac cgatgctacc ttctgtcata gcgacaagtg agtcgagtgg gaaggcaggg
   111961 ttcttttcag agtctgatgc caaatgttgg agcaagagat tcccaacttg aggtccatta
   112021 ccgtgagtga taatcagatc atctccattt ttaatcaatt ttacaagatg cttagctgtt
   112081 tcaactaaag cttcttgttg agcctttgct gatgggtcag aagaaagaat cgcatttcct
   112141 cccaaagcta ctacaatttt acgatttgcc ataaattctc ctttatcaca ctcaatagaa
   112201 tgcgtttaga tttcaattta atgatttttc acatatttta taagaaataa tagattacca
   112261 ttacataaaa gaggaccgga ctaaagctat tagtcgcagc cctcatagct gttggtagac
   112321 ggtttattat ctaaaattat actttaggaa tataaaggtt accaagtgtc gcagccataa
   112381 cagctttgat agtgtgcata cggttttctg cttgatcgaa gtggcgagcg tacttgctgc
   112441 ggaagacttc gtctgttact tccatttctt ctacaccaaa tttttcagca acgtctttac
   112501 cataaacagt gtgagtatcg tggaatgctg gcaagcagtg taggaagatc aagttttcat
   112561 tgcctgcttt tttaactaag tccatattga cttggtaagg tttaagaaga gctacacgtt
   112621 ctgcgaattt gtcttcttca cccattgata cccaaacgtc tgtgtaaaga acgtctgcat
   112681 ctttaactgc ttcatcagca tcttcagtga tgagaacatg tgcgccactt tctttagcaa
   112741 atccttctgc caattcaacg atttcttttt ctgggaagag ttcttttggt gagaagatgt
   112801 gaacattgac accaaggata gcacctgtta cgagcaagct gttggcaacg ttgttacgtc
   112861 catcaccaca gtataccaat gtcaagcctt ccaagcgacc gaagttttct tgaacagtca
   112921 agtagtcagc gagcatttga gttgggtgcc attcgtcagt tagaccgttc catactggaa
   112981 cgcctgagaa ttctgccaat tcttcaacca tacgttggct gaatccgcgg aattcaatcc
   113041 cgtcaaacat acgtcccaat actttagcag tatcttcagt agattctttt ttacccaact
   113101 gaatatcatt tgctccgagg tattctgggt gagcaccaag gtcgatagcc gcagttgtaa
   113161 aggctgcacg agtacgagta gatgtttttt caaataggag agcgatattc ttgccagcaa
   113221 ggtagtggtg ttgaatattg cgttttttca aatctttcaa gtgagctgaa agaccaataa
   113281 ggtattctaa ctctgcacgg gtaaagtctt tttctgctaa gaagctgcgt ccttggaata
   113341 ctaaatttgt cattttatta tttcctcttt ctatttttta cattttctat tgacgaatat
   113401 cgaacagcga ttacacttct tcacgttcaa atggcataga catacaacga ggtccaccac
   113461 ggccccgaac caattcactt ccgcgaatct taatcaagcg aagcccgtat tcttccaaaa
   113521 tcttattggt cacggtattg cggtcataaa caactaccac accaggtgcg atggtcaaag
   113581 tgttagaacc gtcgttccat tgttcacgcg cagctgctac gatattgcca ccaccgcaac
   113641 gaatcaaatg aactttttct acaccaaggt tttgagcaag aagttcagct aagtcacctt
   113701 tctcttcaac gattttaagt ttttcgtttt cgtaagtaac tgagtaaacg tgaaggtcgc
   113761 cttcgatttc tgggtgaata gtgaacttgt catagtctac catagtgaag acagtatcca
   113821 agtgcatgaa tttacggttg ttagcaaatt caaaggccaa aactttcttg aagccaacat
   113881 ttttcttgaa gatgttgacc aaaagttttt cgatagaagc tgcgtctgta cgttgagaga
   113941 tacctactgc aaggacgtct ttagaaagaa ctagctcgtc tccaccttcg atacgcgtat
   114001 cttcttcacg gttgtagacc aaatccactt ttccgccata gattgggtgg tatttgaaga
   114061 tatacttacc gtagagtgtt tcacggttac gagtgtctgc aaacatgtgg ttaagcgata
   114121 cggcgtttcc aattgttgca aatgggtcgc gagtgaaata gaggtttggc atcgggtcaa
   114181 ttgcaaatgg ataatctgat tcaactaagt cagttagatc tttagcttcg tcaggaattt
   114241 ctggcaattc aactttttga atcccagcca ttgttttttc aaccaattct tggttgtcct
   114301 tgatgccgtg aagtaattca cgaatagcaa ccttggtttg acgatcacgg atgttggctt
   114361 cgtctaagta ttcctcgata aattgatcgc ggatttctgg agaggtcaat gattcagcag
   114421 cgagttgttc taggtagaga acctcaattc cttcatcgcg aagagcttgg gcaaatgcat
   114481 catgttcttt ttgagcatct tccaagaaag gaatatcatc aaaaagaagc ctttcaagat
   114541 agtccggcaa caagttttct aactccttgc ctggacggtg caacataact tttttcagtt
   114601 tcccaatttc tgagaagacc tgaattggat gagaagacat gtattttcct ccttaaaaat
   114661 tttgacttgg caccattttg ggtaccgctt acatgtatgt tataacgcaa ttcctaggta
   114721 atgtcaatgg ctataatttc tcggaaaata atataaatta tgatgtttag cacaatttta
   114781 tgttattata cataacatag gatagaatac atagatacaa atgcataaac ttctataaaa
   114841 aggatataaa atttttttaa aaaatttttc aaaaaatata caaatgacca aaaagtgtcc
   114901 aattatcatc tggttatcac ttggatctgt ataaagagaa atgtttgtgt gaaaggataa
   114961 aaagatgcaa cattcttttg aagatagatt ttggagaagc atttcttgtt caattgtaca
   115021 aattatagaa tcttttctga gtatttagga agagataatt atcttattga ccctcttttt
   115081 attttttgtt atagtcgacg aggtgatagc ttagaataat cacttattca caatctgtgg
   115141 aaaagtctgg agagtgaatg gtcttcacac aatgacctga aagaagcctg agaataatta
   115201 tggagagtag cattctgaga ggtgttagca gaatcatatg acagagctgt ttgaagaggg
   115261 aatattgagg agaaaaatcc tgagcctacc agttggagtt ggaaagagct ggctgttaga
   115321 tcatggttta ttatccacaa cctgtggata accttgtgaa caagagaagt tgctaaagaa
   115381 ggagatatat aacgatgaag aaaatcaaac cgcatggacc gttaccaagt cagactcagc
   115441 tagcttatct gggagatgaa ctagcagctt ttatccactt cggtcctaat accttttatg
   115501 accaagaatg ggggactgga caggaggatc ctgagcgctt taacccgagt cagttggatg
   115561 cgcgtgagtg ggttcgtgtg ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca
   115621 agcaccacga tggctttgtc ctttatccga cagctcacac agattattcg gttaaggtca
   115681 gtccttggag gagaggaaag ggcgacttgc tccttgaagt atcccaagct gccacagagt
   115741 ttgatatgga tatgggggtc tacctgtcac cgtgggatgc ccatagtccc ctctatcatg
   115801 tggaccgaga agcggactac aatgcctatt atctggctca gttgaaggaa atcttatcaa
   115861 atcctaacta tgggaatgct ggtaagttcg ctgaggtttg gatggatggt gccagaggag
   115921 agggcgcgca aaaggttaat tatgaatttg aaaaatggtt tgaaaccatt cgtgacctgc
   115981 agggcgcttg cttgattttt tcaacagaag gcaccagtat ccgctggatt ggcaatgaac
   116041 gagggtatgc aggtgatcca ctgtggcaaa aggtgaatcc tgataaacta ggaacagaag
   116101 cagagctgga ctatcttcag cacggggatc cctcgggcac gattttttca atcggagagg
   116161 cagatgtttc catccgtcca ggctggttct accatgagga tcaggatcct aagtctctcg
   116221 aggagttggt cgaaatctac tttcactcag tagggcgagg aactccactc ttgcttaata
   116281 ttccgccgaa tcaagctggg ctctttgatg caaaggatat tgaacgactt tatgaatttg
   116341 cgacctatcg caatgagctc tataaagaag atttggctct gggagctgag gtatctggtc
   116401 cagctctttc cgcagacttt gcttgtcgcc atttgacaga cggccttgag accagctctt
   116461 gggcaaacga tgcagacttg cccatccagt tagaactcga cttaggttct cctaaaactt
   116521 ttgatgtaat tgagttaaga gaagatttga agctagggca acgaatcgct gcttttcatg
   116581 tgcaagtaga ggtggatggt gtctggcatg aatttggcag gggcttcaca gttggtcata
   116641 agcgcctctt gcgaggtccg ctagtagagg cacaaaaggt gcgtgtgatg attaccgagg
   116701 cacaatctat tcctgtattg accaagattt ccctttataa aactcctgga ttatcaaaaa
   116761 aagaagttgt tcaggaacta gcatttgcag aaaaaagcct agctgtggca aagggagaga
   116821 ctcttcattt taggattgaa cgtagtgaaa gtagctcctc tttagaggct aagatttcga
   116881 ttcaaccggg gacaggtgtc catggtgtcg cctatcagga tgagattcaa gtccttgcgt
   116941 ttcaagctgg tgagactgaa aaaagtctga cgctaccaac cttgtatttc gcaggagata
   117001 aaaccttgga tttctatctg aacctaacgg tggatggtca gcttgtggat caacttcaag
   117061 tccaagtttc ataaaagaag aacctttgcg cgatgcaaag gttcttttgg ttattagtga
   117121 cttggtaacc agctgagggt gaaagttagt tgttcagctt ttaagaggtc ttggtgttga
   117181 atagttgata cgagtgtttt gtccagtcgg cattctttga caaagttaaa atggttgtgg
   117241 ttttgtttag tatggatatc cagccattta tcttctttag ctaggtagac tcgtagatgg
   117301 tcaaagagag ggattccgag gtcatagctt ggttttcctg gacaggttgg ataaaatccg
   117361 agagttgacc agatgtacca agcagagaga ctaccattgt cttcatctcc aggataggct
   117421 tcccaacttg ggtgaaaagc tttctgacgg agcgtcttga taagaagggc agtgtagtca
   117481 gggtaatcgc tgtagcggaa gagataagga atgtggaaac taggctggtt ggaaatggct
   117541 atttgtccaa aaggagcagt agccatctcg ctcatttcgt gaatttcgta accatagcct
   117601 gttgtttcaa agaggggagc atcttgacag gctttcaaaa gatagttgct aaaggtttct
   117661 tttccaccca tcagttggat taagccaggg atgtcgtgga gaacgcctaa agtagcttga
   117721 atggcagagc attcagcgta gtctcgcccc caactataag gagagaagtc agggtgaaag
   117781 tttccttgat tgtctcgtgc tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa
   117841 ttttgtgaag cagccttgta ggtttcagcg atttctatgt tctctagttt tttggcacag
   117901 ctggcgatac aaaagtcact ataggcatag tctagagtat ggctaacact ttcgtggtgg
   117961 tcggtagaga ggtaacctag ttcttggtat tgggctagtc cgtggcggcc attgatgccg
   118021 agagggtcgg ctttgctggc tgtttcgagc atggcttgga agagttctcc ttctaggtcg
   118081 ggggccatgt ccttgcaggt gctatctgcg ataataccgt ctaaaagtgt acctggcatc
   118141 ataccccgtt catctggagc cagccatttt ggaaggaaac cagtatcgcg gtagctattg
   118201 aggaaacctt ctaaaaagcg ttgatagtgc tccggtatga taagggcaaa gagggggaag
   118261 gtggtgcgga aggtatccca gaaaccattg ttgctaaaga ggacaccagg cttgacagta
   118321 ccagtagcca gatccatgtg gatggcttgc cctgactcat caacctcata aaaagtctgt
   118381 gggaagagga agagtctgta gagacagtgg tcaaagaagg ttcggttagc ctctcctgtc
   118441 tctataacat caaaacgatg gaggagattt tcccaatccg cttgggcact tgctttacag
   118501 ctatcaaaat cttcttgagg tagattgatt agagcttgag aaggagagat gaaagaagtg
   118561 gctagttgca tctcggtttg actacttact aagtcaattc gccagtctcc agcttcttgg
   118621 ctgatagcaa gaatatccgt gttcatttgc agggcagtga acatcgttag cgaatttttg
   118681 ttggtttcag ttttgccttc ttgtcgcagg gcaagagttc gcttatctac ttgctctact
   118741 gtcagttcat ctgctgcgtg aagatagagg gagagggttt tgccttgctt ttgctccaaa
   118801 cgaatagaag caccgtagca agtcggtgtg agctgggttt caatttgata gcgcagggag
   118861 aaaatcttta gataatgagg ttggaaagag gccttatccc tatcatagga agattggcgg
   118921 tgaaagaggc tgtctccacc cagttgactg gtgacaggtg tcagaaggag ccaagagtag
   118981 tccccaatcc aaggactggg ctggtgagtt aatcgaatcc cctgaaagat aggcagatgt
   119041 ggatcaaaaa accaagatcc atcctggtca ctggcctggg gcacaaagta attcatccca
   119101 aaaggcacgc ctgtgtatgg cagggtattt ccccgagaaa aggcatgctt gttggtagtt
   119161 ccaaagcggg tatcgatggt ttcaagtagt ggtttcatag tctttccttt agctgttttt
   119221 ctacattata tcagaaaaag agggccttta gaaaaggagt ttcaaagata actattttgt
   119281 agaaaaatga ctatcatttg tgtatgtatt ttctgtctca aaagctatat actgaaaatg
   119341 aaacttgttt gaaagaggga attgcacgat gatttattcg aaagaaattg ttagagaatg
   119401 gctagatgaa gtagcagagc gtgccaagga ccatccagag tgggtggatg tctttgagcg
   119461 ttgctacacc gataccttgg acaatacggt tgaaatctta gaagatggtt caacttttgt
   119521 cttgactggg gatattcctg ccatgtggct tcgagattcg acagcccaac tcagacccta
   119581 ccttcatgta gctaaaagag atgccctcct gcgtcagacc attgcaggtt tggtcaaacg
   119641 tcagataacc ttggtactca aggatcccta tgctaactcc ttcaacattg aggagaactg
   119701 gaaagggcac cacgagactg accacacaga ccttaacggc tggatctggg agcgcaagta
   119761 tgaggtggat tcgctttgct atcctttaca gttggcttat cttctctgga aagagactgg
   119821 cgagactagt cagtttgatg aaacttttgt cgcagcgact aaggaaattc tccatctatg
   119881 gacagttgaa caagaccaca agaactctcc ttatcgtttt gtccgagata cggaccgtaa
   119941 ggaagacacc ttggtaaatg atggctttgg acctgacttt gcagtgacag gtatgacttg
   120001 gtcagccttt cgtccgagtg atgactgctg ccagtatagc tacttgattc cgtcaaatat
   120061 gtttgctgta gtagtcttgg gttatgtgca agaaatcttc gcagcattaa acctagctga
   120121 tagccagagt gttattgctg atgccaagcg tcttcaggat gaaatccaag aaggaatcga
   120181 aaactacgct tacaccacca acagtaaggg tgaaaagatt tatgcctttg aagtggatgg
   120241 cctaggaaat gccagcatta tggatgatcc aaacgtacca agtctactag ctgcgcccta
   120301 tctgggctac tgttcggtcg atgatgaagt gtatcaagct actcgccgta ccattctgag
   120361 ccctgaaaat ccatatttct accaaggaga atacgcaagc ggtctcggca gttctcatac
   120421 cttctatcgc tatatctggc caatcgccct ttctatccaa ggcttgacaa caagagataa
   120481 ggcagagaaa aaattcttgc tggatcagct ggttgcttgc gatggcggta caggtcttat
   120541 gcatgaaagc ttccacgtgg atgacccaac tctctactct cgtgaatggt tctcctgggc
   120601 taacatgatg ttctgtgagt tggtcttgga ttacttggat attcgctaat actcttcgaa
   120661 aatctcccaa acaacgtcag ctttatctac aacctcaaag cagtgctttg agcaacctgc
   120721 ggctagcttc ctagtttgca ctttgatttt cgttgagtat tagctcaacc gattcttatc
   120781 agaatcacaa gtttacattt aaaacgttaa aatttaaatt tagaatgagg ttttacttca
   120841 tggaaaatgt tgttgtacat attatctcac atagtcactg ggaccgtgag tggtacttgc
   120901 cttttgaaag ccatcgtatg cagttggtgg aattgtttga caatctcttt gatctctttg
   120961 aaaatgaccc tgagttcaag agtttccact tggatggaca aactattgtc cttgacgact
   121021 acttacaaat tcgccctgaa aatcgtgaca aggtccaacg ctacattgac gagggcaaac
   121081 ttaaaattgg tcccttttac atcttgcagg atgactactt gatctccagt gaagccaatg
   121141 ttcgaaatac cttgattggt caagcagaat gtgcaaaatg gggcaaatct actcagattg
   121201 gttatttccc agataccttt ggaaatatgg gacaagcgcc tcaaattctt caacaatcag
   121261 gcattcacgt ggcagccttt ggtcgtggtg tgaagccgat tggatttgac aaccaagtcc
   121321 tcgaagatga gcagtttact tcccagtttt cagaaatgta ctggcagggt gcggatggta
   121381 gtcgtgtttt aggtattctc tttgccaact ggtacagtaa tgggaatgaa atcccagttg
   121441 acaaagatga ggccttgacc ttctggaaac aaaaattgtc agatgtgcgt gcctacgctt
   121501 cgaccaacca atggttgatg atgaacggct gtgaccacca gcctgtacag aaaaatctga
   121561 gcgaagccat tcgtgtggca aatgaactct tcccggatgt aatctttgtt catagttctt
   121621 ttgatgaata tgttcaagct gtagaaggtg cgcttcctga acacttatca actgttacag
   121681 gcgagttgac cagtcaggaa acagatggct ggtacacact tgccaacact tcttcatccc
   121741 gcatttacct aaaacaagcc ttccaagaaa atagcaacct cctagagcaa gtggtagaac
   121801 ccttgactat tatcactggt ggacacaacc acaaggacca gttgacctat gcttggaaaa
   121861 cacttttgca gaatgcgcca catgatagta tctgtggctg tagcgtggac gaagttcacc
   121921 gcgagatgga aacgcgtttt gccaaggtca accaagtagg aaactttgtt aaaagtaatt
   121981 tgctcaacga gtggaagggt aaaattgcta cggataaggc tcaaagtgac tatctcttta
   122041 ctgtcattaa cacaggcttg catgataagg tcgatactgt ctgcacagtg attgatgtgg
   122101 cgacttgtga tttcaaggaa ttgcacccaa cagaaggcta caaaaagatg gctgctctta
   122161 tcttgccaag ttaccgtgtg gaggacttgg atggtcgtcc tgtagaggct acaatcgaag
   122221 acctcggagc taattttgaa tacgatttac caaaagataa gttccgccaa gctcgtattg
   122281 ctcgacaagt gcgcgtgacc attccagttc acctagcacc gctttcttgg acaaccttcc
   122341 aattgctgga aggagaacaa gaacaccgtg agggtattta ccaaaacgga gtgattgata
   122401 caccattcgt aacggtgagt gtggatgaca acatcacagt ctatgacaag acaactcacg
   122461 aagcctatga agactttatc cgctttgaag accgtgggga cattggaaac gagtatatct
   122521 atttccaacc aaaaggaaca gagccaatct ttgcagagct taagggccac gaggtcttgg
   122581 aaaacacagc ttgctatgct aaaatcttgc tcaaacatga attgaccgtg cctgtcagtg
   122641 cggatgaaaa gctagaagaa gagcaacaag gtatcatcga gtttatgaag cgtgaggctg
   122701 gacggtcaga agaattgaca aacattcctc tggaaactga gttgactgtc ttcgttgaca
   122761 atccacaaat ccgcttcaag actcgcttta ctaacactgc caaggatcac cgtatccgta
   122821 tcttggtcaa gactcataac acgcgtccaa gcaatgattc tgaaagtatc tatgaggtgg
   122881 tgacacgacc aaacaaacca gctgcttcat gggaaaatcc tgaaaatcct caacaccaac
   122941 aagcttttgt cagtctgtat gacgatgaaa aaggggtgac tgtatccaat aagggattga
   123001 atgaatacga aatccttggg gataacacca ttgccgtgac cattttgcgt gcatcaggtg
   123061 agctaggtga ctggggctac ttcccaacgc cagaagcaca atgcttgcgg gagtttgaag
   123121 tcgagtttgc acttgaatgc caccaagccc aagaacgttt ctcagcctat cgtcgtgcca
   123181 aagccttgca gacaccgttt accagccttc agcttgctag acaggaagga agcgtggttg
   123241 cgactggtag cctcttgagc cattctgttc tcagcatacc gcaagtttgt ccaacagcct
   123301 ttaaagtggc ggaaaatgaa gaaggctatg tcctccgtta ctataatatg agtcaagaaa
   123361 atgtgcgcat atcagaacat caacaaacca ttcttgactt acttgagcga ccatatccag
   123421 ttcattcagg actattggct ccacaagaga ttcgtacaga attcatcaaa aaagaagaaa
   123481 tttaatttca aaaagtaaac atcaaaagaa aggaggggcg aaaaagtaag aactaactgc
   123541 tgattcgccc ctttttatgg taaaaacaat gaccattgca acgattgata tcggagggac
   123601 tgggattaag tttgccagtc tgactcctga tgggaaaata ctggataaga caagtatttc
   123661 aacgcctgaa aacttggagg atttactagc gtggctagat caacgcttgt cagaacagga
   123721 ttacagtggg attgctatga gcgttccagg tgcggtcaat caagagacag gtgtgattga
   123781 tggcttcagt gcggtgccct acatccatgg cttttcttgg tatgaggcgc ttagctctta
   123841 tcagctacct gtccatttag aaaatgatgc caactgcgtt ggactcagtg aactactagc
   123901 tcatccagag cttgaaaatg cagcctgtgt cgtgattggg acagggattg gcggagccat
   123961 gattatcaat ggtagacttc atcgaggtcg ccacggtctg ggtggagaat ttggctacat
   124021 gacaaccctt gcctctgctg aaaaacttaa taactggtcg caactagcat caactgggaa
   124081 tatggtacga tacgtgattg aaaaatctgg tcatactgat tgggacggtc gcaagattta
   124141 ccaagaggcc gcaactggta atgctctttg tcaagaagcc attgagcgca tgaaccgcaa
   124201 tctggcgcaa ggcttgctca atatccagta tctcatcgat ccagatgtca tcagtctggg
   124261 tggctctatc agtcaaaatc cagattttat ccaaggtgtc aagaaggctg ttgataactt
   124321 tgtcgatgcc tacgaagaat acacggtcgc accagttatc caggcctgca cctatcacgc
   124381 agatgccaat ctctacggtg cccttgtcaa ctggctacag gaggaaaagc aatggtaaga
   124441 tttataggac ttagtcccaa acaaacgcaa gctattgagg ttttaaaagg tcacatttct
   124501 ctaccagatg tggaagtggc tgtcactcag tctgaccaag cctctatctc tatcgagggt
   124561 gaggaaggtc actatcaatt gacctaccgc aaacctcacc aactttatcg tgccttatcc
   124621 ttgttggtaa cagttctagc agaagctgat aaagtagaga ttgaggaaca agcagcttac
   124681 gaagatttgg cttacatggt tgactgttct cgaaatgcgg tgctgaatgt ggcttctgcc
   124741 aagcagatga ttgaggtctt ggctctcatg ggctactcaa cctttgagct ttacatggaa
   124801 gacacttacc agattgaagg gcagccttac tttggctatt tccgtggagc ttattcagca
   124861 gaggagttgc aggaaatcga agcctatgcc caacagtttg acatgacctt tgtaccatgc
   124921 atccagacct tggcccactt gtcggccttt gtcaaatggg gtgtcaagga agtgcaggag
   124981 ctccgtgatg tagaggacat tcttctcatt ggcgaagaaa aggtttatga cctgattgat
   125041 ggcatgtttg ccacgttgtc taaactgaag actcgcaagg tcaatatcgg gatggacgaa
   125101 gcccacttgg ttggtttggg acgctacctg attttgaacg gtgttgtgga tcgtagtctc
   125161 ctcatgtgcc aacacttgga gcgcgtgctg gatattgctg acaaatatgg tttccactgc
   125221 cagatgtgga gtgatatgtt cttcaaactc atgtcagcgg atggccagta cgaccgtgat
   125281 gtggaaattc cagaggaaac tcgtgtctac ctagaccgtc tcaaagaccg tgtgactctg
   125341 gtttactggg attattatca ggatagcgag gaaaaataca accgtaattt ccgcaatcat
   125401 cacaagatta gccatgacct tgcatttgca gggggagctt ggaagtggat tggctttaca
   125461 cctcacaacc attttagccg tctagtggct atcgaggcta ataaagcctg ccgtgccaat
   125521 cagattaaag aagtcatcgt aacgggttgg ggagacaatg gtggtgaaac tgcccagttc
   125581 tctatcctac caagcttgca aatctgggca gaactcagct atcgcaatga cctagatggt
   125641 ttgtctgcgc acttcaagac caatactggt ctaacggttg aggattttat gcagattgac
   125701 cttgccaacc tcttaccaga cctaccaggc aatctcagcg gtatcaatcc caaccgctat
   125761 gttttttatc aggatattct ttgtccgatt cttgatcaac acatgacacc tgaacaggac
   125821 aaaccgcact tcgctcaggc tgctgagacg cttgctaaca ttaaagaaaa agctggaaac
   125881 tatgcctatc tctttgaaac tcaggcccag ttgaatgcta ttttaagtag caaagtagat
   125941 gtgggacgac gcattcgtca ggcctaccaa gcggatgata aagaaagttt acaacaaatc
   126001 gccagacaag aattaccaga acttagaatc caaattgaag acttccatgc cctctttagt
   126061 caccaatggc tgaaagaaaa caaggtcttt ggtttggata cagttgacat ccgtatgggc
   126121 ggactcttgc aacgcatcaa acgagcagaa agccgtatcg agttttatct ggctggtcag
   126181 cttgaccgca ttgacgagct ggaagttgaa atcctaccat ttactgactt ctacgcagac
   126241 aaggatttcg cagcaactac agccaaccag tggcatacca ttgcgacagc gtcgacgatt
   126301 tatacgactt aatactcttc gaaaatctct tcaaaccacg tcagcttcca tctacaacct
   126361 caaaacagtg ttttgagcag cctgcagcta gcttcctagt ttgctctttg attttcattg
   126421 agtataaaaa caagaacacc ttgcttggcg cagggtgttt cgcgtgaaac agaagaatta
   126481 tctggtttca aatgctacag ttagacaaac ttatgataaa gtcgggatta taacacagag
   126541 ataagaagaa atagatagtg ggacgagttt aaataggatt actcgctatg aaatgttaat
   126601 tacttttgat ggcttaacaa atattatcaa taatgtagtc attcgaatga tttcccttgc
   126661 aatatagtga aattaacaaa aagaaaaaac gctgatcaag cgtttttctt ctgtattgat
   126721 tcgtattgaa tgcttacttc acttctgtaa acacaacgtg tttgcgaagt tttggtgagt
   126781 atttcttcaa ttgaaggcgg tctggagtgt tacgtttgtt tttagaagta aggtacaagc
   126841 gttcaccaga ttctttgtgt tcaagtgtaa tatttacgcg catggtatct cccttctatt
   126901 attcagctga tgcagcttta gcgattttac gtcctttgta gtatccttta agtgatacac
   126961 ggtgagaacg tgagtaatct ccagtagttt cgtcaaagtt tacagatgga gctgttactt
   127021 tgtagtgtgt acgacgtttg tttttcttcg cttttgaagt gcgacgtgca ggtactgcca
   127081 ttttgatttc tcctttaggt atttatattc gattcaatct actgattttc atcaaccata
   127141 ctaggataac acattttttt tgtaaagtaa agttacttga caaaaaaaga tgaaaaaatt
   127201 ctcctgtccg acttgtcaga caggagaaga tgttaaatat caatctcaaa tggttcgtca
   127261 atggtttctg atacgtattt tccgtctttc ttccgttgct tgacacactc tgtgaggaga
   127321 tattcgattt gcccattgac tgaacgaaag tcgtcttctg cccatgatgc gagtgcagcg
   127381 tataactttg ttgagagtcg aagggggatc tgcttttttt tagcttcagc catctttagt
   127441 aaagacttcc tgtgttgaca attggttgtg catcatgatt gccacaaaga acgacaagga
   127501 gatttgaaac catggcagct tttcgttctt cgtcaagttc taccaattcc ccttcattga
   127561 gccgttctag tgccatttca accattccta cagcaccatc tacaatcatc ttccgtgcat
   127621 caataatggc agatgcttgt tggcgttgaa gcataacggc agcaatttct ggagcataag
   127681 ctaggtaagt gatacgtgct tcaaggattt ccaagccagc atcctcaaca cgactttgga
   127741 tttcttcacg aatacggtta gcaacaattt cgctagagcc acggagacta ccttcatctg
   127801 cttgcccgtc acccgtagta tccacattag gagacacatc gtaaggatag atgcggacaa
   127861 tattacggag ggcgctatca cattgcaatg aaagatattc tttgtagtta tcaacgttga
   127921 agactgcctt agcggtatcg acaactctcc aagttaccgc gataccgatt tctacagggt
   127981 ttcctaagca atcattgatt ttttgacgag aattgctcaa ggtcatgact ttgagggaaa
   128041 tgtgtttctt gccaatttca agatttacat cattgtcatt tgatgattta gctcctaaaa
   128101 aaggagattt tgtgctaaca tcaccacttt gtccaagtcg agtgtggttt gcagggttga
   128161 ctgctacgct gaagggattg acaaagtaaa aaccaggttc tttgatggta cctgtataat
   128221 taccaaagag tgtcagaacc agagcttcct gaggtttgac aacttttaaa ccagcatgag
   128281 ctagacctgc aattacgatt agtaaaggtc cgataataat tccaaaaatg ttttccgaac
   128341 caacacccat tataaatata aagataccaa gtatgattgt caactcaatg agaatcaatg
   128401 cgaatacacc atttggtttt gaattgatta gtttttcagt cataagaatg acctcccatt
   128461 atttgatatc taaatgatat cactttgttt ttaaaagtca atagaaagtt gaaaataatc
   128521 actaaaaact ttcagcccaa taatttcttt taaaaggtga gattatattg tgctcaaata
   128581 ctcttttatt cttataattt ttacactata attgtagtta gaaaggaaga gaaatgtttg
   128641 attatagagc actagttatt ttgatgactt tgatggatca ttgtgagcta tcattatatg
   128701 aattatctgt taaggtgagc ttacctataa aggaagtcaa agaaggaata gattatttag
   128761 tgccttatct agctaataaa gggatagtgc tggataaaaa acaaggtcgc tatagtttat
   128821 caaatcgtac gaagcagtct ttgacagata ttattaagtc ggatgaattg gttttaccaa
   128881 agtcgactcg cttagcttta atctatcttt acactttttg ccgattagat tttatatcga
   128941 ataatcatta ccaagacttt ttgaaagtaa gtaagaatac aaccttatct gatattcaat
   129001 cattaagaaa gattatgtta gataatgatt tggagctagg gtacagtaga gcaaaaggtt
   129061 atactttaca cggttcagag tggaataagc accgcttagc ttttcaaatg gttagtgagt
   129121 tgctggaatc ctccataggg atttggggtt tggattatgt tttatccagt tgggggtatt
   129181 cattaactta tgatttgata aatcaggtag ttaaagatta ttatgagaag ctacagctag
   129241 tacctattgt taatcaatta aaagtttacc ttttcggttt agtattcatt ctgtgtaggt
   129301 atcaaaggga tgttgaaaga gtatgtcttt cagagacatt agtatctcct gttattcaag
   129361 atataaccac tattttattg gatacagtgg ttgatttggg aattatagat acggtgtttt
   129421 ctgaggatga ttatcgctat atcaccgttt tattatcaag ttgctttgaa ggtgaagtag
   129481 atgttgctcc ggtttacttt aatcaattaa cagaggctat tataagtaga atggaagata
   129541 tttctttgtt acattttaaa caaagggaag gattgagaga aaatcttcgc cgccacctta
   129601 taccggctta ctatagatta aagttcggcc tacctagttc aaatgaatat gtattgcatg
   129661 ttaaagaata ttatcctgat ttatttgaat tagtcaaaga ttctttgatg cccttgatgg
   129721 acgctattga caatcccata cctgatagtg aaacagcata ttttgttatc catttcggag
   129781 gttatttaaa gaaagcagat actttgcctc aaaaatggta taaagcagca atcatttgtc
   129841 ctaatggtgt tagttcttca ttgatgttaa aagagaatct attagcatta tttcctcaaa
   129901 ttgagtttat aggaacctca aagattgatg atttacaggt gaaagctagt agtgactatg
   129961 atatggtttt ttctaccata aaggtggaga cagaaaagcc aaattatcta gtttcggtta
   130021 tgatgactga agagcaagca atacaactag tagaactagt gttaaaagat tttccgaatt
   130081 tagagtatgg ggattttgag attgaacaaa ttctgaatat tgtcaaaaga tatggaatta
   130141 ttacacaaga attggaatta agattggcgt taaagaatta tctttaccaa aaaaatgata
   130201 gaaaggaaat tgtaccagtg ctagaacaac tcattaccaa agaaacctat caggttagtt
   130261 cgcaaaaatt aggatggaag gaggcgattc gtttagcagc taaaccgctt ttggatcaag
   130321 ataagataac tgagaactac cctgaggcaa tgattcaaaa agtagaagag tttgggcctt
   130381 ttattaattt agggaaggga gtagcaattc ctcacgctcg gccagatgaa ggtgtgaatg
   130441 aaataggaat gtcaatgtta gttttggaag aaccgattta tttattggat aatccagaac
   130501 aagaggtaag attgttgatt tgtattgcag ccattgataa tgagagtcat ttaaaggctt
   130561 tgtcacattt aacaacaatt ttaagagata aaaatcatgt tcaaacttta atatcatcaa
   130621 aaaactatga tgacattaaa atgataatta aacaggagga ttagataatg ttaaaaattg
   130681 gtacagcttg tggttcagga ttaggttcaa gttttatggt acagatgaat attgaatctg
   130741 tattgagtga tttgaatgtt tcagatgtag aagttgaaca ttatgattta ggtggagcag
   130801 atccaaatgc agctgatatt tggattgttg gtcgtgatct agctgattca gctagtcatc
   130861 ttggagatgt tcgtatctta aatagtatta ttgatatgga tgaactacga gaattaatta
   130921 ctaaactttg tgaagaaaaa ggacttatat aggaggctag cgtcatgatg aagttcatat
   130981 tggatattgt tagtacacca gctattttag tagctttaat tgcaatttta ggattagttc
   131041 ttcagaagaa gaaattacct gatattatta aaggtggaat taagaccttt gttggtttct
   131101 tagttgtatc tggtggtgca ggaattgtac aaaattcttt aaatccattt ggtaccatgt
   131161 ttgagcatgc ttttcattta tctggcgttg tgccgaataa tgaagcaatt gtagctgtag
   131221 ctttaacaac atatggctca gctactgcac tgattatgtt tgcaggcatg gtgttcaata
   131281 tcttaatcgc tcgttttact cgatttaaat atattttttt aacagggcac cacactctat
   131341 atatggcatg tatgattgcg gtcatttcag ttctttggga tattggttga gtggttttac
   131401 tggtagcctt atcggtgaca aatcaaaatc aacagaggac attaaatttc caaagagttt
   131461 agctttttta cgtgatagta ctgttagtat cactttatcc atggcagtta tttacattat
   131521 tgtagctatc tttgcagggt cagaatatat agaaaaagaa atcagtagtg gtacaagtgg
   131581 tctagtttat gctttacaat tagcaggtca atttgcagca ggggtatttg ttattttagc
   131641 aggtgttcgc cttattttgg gcgaaattgt tccagccttt aaaggtattt cagagcgtct
   131701 tgtacctaat tcaaaacctg ctttggattg tccgattgtt tatacttatg cacccaatgc
   131761 agttctaatt ggatttatct ctagttttgt tggtggttta gtaagtatgg caattatgat
   131821 tgcttcagga acggttgtta tcttaccagg tgttgtgcct catttcttct gtggagcgac
   131881 tgcaggtgtc attgggaatg catctggtgg tgttcgtgga gccactattg gagcattttt
   131941 acaaggtatt ttaatcagtt ttcttccagt ctttttaatg ccagttttgg gaggacttgg
   132001 tttccaagga tcaactttct cagatgcaga ttttggtcta tcaggaatta ttttaggaat
   132061 attaaatcaa tttggctcac aagcaggcat tgtgattggt cttgttctta ttctagcagt
   132121 tatgtttgga gtatccttta ttaaaaagcc atctgcaacg gaggaataag ggatgatttt
   132181 aagtaaaaat agagaagatg ggttaagaaa atttgcgact aacatccgat taaatactct
   132241 tagaacattg aatcatcttg gattcggaca ttacggagga agtctgtcta tcgtagaagt
   132301 tttagcagtg ctttatggtg aaataatgcc aatgactcca gaaatatttg cagcacgaga
   132361 tagagattat ttcatattat caaaaggtca cggaggacca gctctataca gtacactcta
   132421 tttgaatggt ttctttgaca aagaattctt atattcttta aatacaaatg gaaccaaatt
   132481 accgtctcat cctgatagaa atctaacgcc aggcatagat atgacaacgg gctctttagg
   132541 acaaggaatt agtgttgcaa ctggacttgc atatggtcag agaataagaa agagtccctt
   132601 ttatacttat gctattgttg gagatggtga gttaaatgag ggacaatgtt gggaggctat
   132661 acagtttgct tctcatcaac agttatccaa cttaattgta tttgttgatg ataacaaaaa
   132721 acaattagat ggttttacaa aggatatttg taatccaggt gatttcgtag aaaaattttc
   132781 agcatttgga tttgaatcca ttagggtcaa gggttcagat attagagaaa tttatgaagg
   132841 gattgtccaa ttaaaacagt caaataattc atcacctaag tgcattgtat tagatactat
   132901 taaaggtcaa ggggttcaag agctggaaga aatgaaatcc aatcatcatc ttcgccctac
   132961 tgtagaggag aaacaaatgt taacttcagt tgtagaaaga ttaagtcagg aattggagga
   133021 aacagaatga tgagaagtac gaaagaatta cggcatgtat atagagactt ccttttagag
   133081 gctaatcaaa gtgattctga tatagtagtc ttagaagccg atttgtcaag ttcgatggct
   133141 actcataatc ttgaaaagga ctttggagac cgttatgtga atgttgggat tatggaagca
   133201 gaaatggtcg gccttgcagc aggcttgtct attcaggggt ttagacctta tcttcataca
   133261 tttggtcctt tttcttcacg aagggtattt gatcaattat ttatttctct tggatacgca
   133321 caattggatg ccactgtgat tggatcagat gcaggagtaa ctgcagaaat gaatggtggg
   133381 acacatatgc catttgaaga aattggattg ttacgtttaa ttcctaaatc gatcattttt
   133441 gaagcaactg atgatatcca atttcgtgaa atattgaacc agacattaga cttaaaagga
   133501 ctaaaatata ttcgaacaat tagaaaagct ccagttcctg tgtatcaagg tggagaagat
   133561 ttttctaaag gctacattga gttaagacat ggtgaagatg ttgtaatcgt tgcttctggc
   133621 ataatggttg ctccaagtat tcgagttgta gatgaactgt ctaaattagg ttattcagta
   133681 ggtgtgatag atttatttag aatcaaaccg ataccagaac agataaaaac aatgttaagt
   133741 ggaaaaacta tatttactgt agaaaaccac aatcagatag gtggaattgg cagtgcttta
   133801 tgtgaattat tctctgatga tggaataaca aaaattcatc ggatgggtgt tcaagaaaga
   133861 ttcggtcaag tagggaaaat ggattatctt cttaatgagt atggtttgag tgaatcgaat
   133921 ataaaagaga aggttctaga aatttataat gcaagataga tgttaaatac acttatctga
   133981 aagaatttct gtaaaaatta cagtacgtta tttaaagaaa gcggattaaa aagcatattc
   134041 tggtcatcag aaagtgcact aatccgcttt gttgttttta attttaaata tttcacatgt
   134101 gtatagaatt ttctgaaaat tcaagaattt tattctgttc attgccttta aattgtgcta
   134161 taatagtaaa aactgaaatg ggagggataa gatgactgaa ttagataaac gtcaccgcag
   134221 tagcatttat gacagcatgg ttaaatcacc taaccgtgct atgcttcgtg cgactggtat
   134281 gacagataag gactttgaaa caccgattgt gggagtgatt tcgacttggg cggaaaatac
   134341 accatgtaac attcacttgc atgatttcgg gaaactggct aaagaaggtg tcaaatctgc
   134401 aggcgcttgg cctgtacagt ttggaaccat taccgtagca gacgggatcg ctatgggaac
   134461 gcctggtatg cgtttctctc taacatctcg tgacatcatc gcggactcca tcgaggcggc
   134521 tatgagtggt cacaacgtgg atgcctttgt cgctatcggt ggctgtgaca agaacatgcc
   134581 tggatctatg attgctattg ctaatatgga tatcccagct attttcgcct atggtggaac
   134641 tattgcaccg ggaaatcttg atggtaaaga tatcgacttg gtttctgtct ttgaaggtat
   134701 cggaaaatgg aaccacggtg acatgacagc tgaggacgtg aaacgtcttg aatgtaatgc
   134761 ctgccctggc cctggtggct gtggtggtat gtatactgct aataccatgg caactgctat
   134821 cgaagttcta gggatgagtt tgccagggtc atcctctcac ccagctgaat cagctgataa
   134881 gaaagaagat atcgaagcag caggacgtgc tgttgttaag atgttggaac ttggtctcaa
   134941 accatcagat atcttgactc gtgaagcctt tgaagatgct attactgtaa cgatggctct
   135001 cggtggttct acaaacgcca ctcttcactt gctcgccatt gcccatgccg caaatgttga
   135061 cttgtcactt gaggacttca atacgattca agaacgtgtg cctcacttgg ccgacttgaa
   135121 accatctggt cagtatgtct tccaagacct ctacgaagtc ggtggtgtcc ctgcggttat
   135181 gaagtacttg ttggcaaatg gtttccttca cggagatcgc atcacatgta ctggtaagac
   135241 tgtagctgaa aacttggctg actttgcaga cttgactcca ggccaaaaag ttatcatgcc
   135301 acttgaaaat ccaaaacgtg cggatggtcc gcttatcatc ttgaacggga accttgctcc
   135361 tgacggtgca gttgccaagg tatcaggtgt taaagtgcgt cgtcacgttg ggccagctaa
   135421 ggtctttgac tcagaagaag atgcgattca ggccgttctg acagatgaaa tcgttgatgg
   135481 cgatgtagtc gttgttcgtt ttgttggacc taaaggtggt cctggtatgc ctgagatgct
   135541 gtcactttct tcaatgattg ttggtaaagg tcagggagat aaggtggccc tcttgacgga
   135601 cggacgtttc tctggtggta cttatggtct ggttgttgga catatcgctc ctgaagctca
   135661 ggatggtgga ccaattgcct atctccgtac cggcgatatc gttacggttg accaagatac
   135721 caaagaaatt tccatggccg tatccgaaga agaacttgaa aaacgcaagg cagaaacaac
   135781 cttgccacca ctttacagcc gtggtgtcct cggtaaatat gcccacatcg tatcatctgc
   135841 ttcacgcgga gccgtgacag acttctggaa tatggacaag tcaggtaaaa aataaactca
   135901 tactcgaaaa tctcttcaaa tcacgtcaac gtcgccttgc cgtaggtatg gttactgact
   135961 tcgtcagttc tatccacaac ctcaaaacag tgttttgggc tgacttcgtc agttctatcc
   136021 acaacctcaa aacagtgttt tgagctgact tcgtcagttc tatccataac ttcaaaacag
   136081 tgttttgagc aacctgcggc tagttttcta gtttgccctt tgattttcat tgagtatcaa
   136141 aaagcaagcc attttcggct tgcttttttc atctttaaaa gtgattggcc tgcttaacga
   136201 ggtggtagtc caagggcaat acggccatag cgactgattc gtgtgatttt ccaagcaggc
   136261 gaccaggtaa cttcaacctt gatatctttg ataccctcga tttgtttcag acctgccacg
   136321 atttcaatag gcaggctttc ggcgcaatca caggcagtat cggtgaaggt catgacaatc
   136381 ttgcagagcc ccgtttcatc cagattgatt tcataaatca gacctagatt gtaaacatcc
   136441 aattccacat ctgtatcaaa aactttctct agtttttcga taatttggtc ttgcaaggcc
   136501 aaagcacggt cattgatttt gatatcgtct ctcatagcag tccctccacg tgataaatat
   136561 cctctatttt ctcatgattc tgacaatttg gcaagttttt gatgaatttt ctgaaaaata
   136621 tgataaaatg aagaaaatac gggatcaagg ggaagtctat ggagcagatt ggaaaagtct
   136681 ttagacaatt acgagaatca agaaatatct cactgagaca agcaaccgga ggacaatttt
   136741 cgccgtctat gttgtcccgt tttgaaacag gtcagagtga gctttcggtg gaaaagtttc
   136801 tatttgctct ggaaaatata tctgccagtg tggaggagat cctctttctg gcgagaggtt
   136861 tccagtatga tacagattct gagttgagaa aagaaattac agatgtcttg gaaccaaaga
   136921 atatagcacc tcttgaggac ttatatcgca gggagtatca aaagcatgcc cattctcaca
   136981 acaaacagaa acatattcta aatgccatta tgatcaagtc ttatatgaag agcatggatg
   137041 aaagggtaga gttaacagca gaggaaggaa aagtccttca tgattatttg ttttctaccg
   137101 agatctgggg aatctataaa ctcaatttat tttcagtcag ttctccattt ttatctgttt
   137161 ctctttttac tagatatgta cgagaaatgg tacgtaaatc tgattttcta atggaaatgt
   137221 ctggcaatcg aaaccttttt catactatac tattgaatgg ctttttagct agtattgagt
   137281 gtgaagaatt taccaatgcc tattatttta aacgtgttat cgaagagcat ttctacaagg
   137341 aaaatgagac ctatttccga attgtttatc tgtgggcaga aggtctcctt gatagcaagc
   137401 aaggtagagt caaggaaggc cagaaaaaga tggaggatgc tgtccgtatt tttgagatgc
   137461 ttggctgtaa taaatctgcc gaatactata gaaatacgac cgaatgttga atatctgcaa
   137521 actaagaaaa aatttgaagc gatagaactg ttgccctttc tcaggtcatt acaaaagttc
   137581 tatcgttttt tgctcatttt atttgttgca tatattcaaa agaattgttt cgcaaattca
   137641 taagtgctat actaaagcta ttcttgatgt agaacttaga acaaggaggg agattatcta
   137701 tgaaactatt gtttagaaat caagcttatc gcctattgac tttgtcacgc ttcttcaatg
   137761 cttttggtgc ttcgattttc aacctggtct ttatcgtcta tgcatcgacc ttgccacaag
   137821 catcttttgc tgttgctatg gcgaatattg tcatgattct tccgaccctc tttacagttt
   137881 ttgcagggat tcgggcagat tacacgaggg acaaggtcaa atggatggtc tatagcggtt
   137941 tgtttcaggc ggttctattt tttctagcag ccctagttgt tcagcaagct agtctctttg
   138001 ccttttctag cctgtgtttg atcaatgtca ttagtgatgt catcagtgat tttgcaggtg
   138061 gcctgcgtat gcctcttatt aaggaaaaag tagctgaaga tgatttgatg gaggcttatt
   138121 ctttttcaca gttcatcacc tatatttcag ctattggtgg tcaagctttc ggagtctggc
   138181 tcttagctct atcggtcaat aatttttctc tcgttgcggg aatcaatgcc tgctttttcc
   138241 tagtatcagc cactatcctc tttttaggaa aaagcaaatt gagcctgtca atgtcatctg
   138301 ctgatggtga aaacttaaaa aatgagaagc tttctatcaa agaccggttc ctaacaattt
   138361 accgaaattt acgtctcgtt tttcttaaaa gtggacagaa aaactttggt tttatgctct
   138421 ttgctgtctt gcttattaat tccttgggtg gcgctttggg tggaatttat aatatcttct
   138481 ttttgagcca ttctctcttg aatttttctt atacagaggc actatttatc aatcaattct
   138541 gtgttttagt agcaatcatc atcagtagcc ttacgggcaa tgattatttt gggaagcagt
   138601 ccttgcctag attgatgatg tgggagaccg taggacttag tctagttggt ttggctaatt
   138661 tattcaatca agtcgtgctt ggtttgctat ttctcttctt tactctgtat gtgtctggta
   138721 aagttcaacc aaagattagt gccatgctca tgaaaaatct agctccagag gttctagctc
   138781 gtactagtaa ttttttcggt ctattgttta ccttatccat acctgtggga acagcttgtt
   138841 tttcactagt agccgtatgg aacatgcagt tgacttggat gctatttgtt ggtttttcct
   138901 tgctagctat ttttttaaca attcttaatc tcaaaaatga tatctaaatc ctaatttttt
   138961 tcttactgtt ttaatccctc tatttatggt aaaataagac tattaagttt aaagaggatt
   139021 ccctatgaaa ttacaaaaac caaaaggaac gcaggatatt ttacctgctg agtctgctaa
   139081 gtggcagtac gttgagggct ttgcccgtga aattttcaag cgctacaact acgcagaagt
   139141 gcgtacgcct attttcgagc attacgaggt tatcagccgc tctgtcggag atacaacgga
   139201 tatcgtaacc aaggaaatgt acgatttcta tgacaagggt gaccgccata ttaccctccg
   139261 tccagaagga actgcgcccg ttgtccgttc ctatgtggaa aataaactct tcgccccaga
   139321 agtgcaaaag ccaagcaagt tctactacat gggacctatg ttccgttatg agcgtccaca
   139381 ggcagggcgc ttgcgccaat tccaccagat tggtgttgag tgttttggct ctagcaatcc
   139441 agctaccgat gtggaaacaa tcgttatggc agcccatttt ttgaaggaaa tcggtattca
   139501 aggtgtcaaa ttgcacctca acactcttgg aaatcctgag agccgtgcag cctaccgcca
   139561 agccttgatt gactatttga caccgctcaa ggagaccttg tctaaggata gccaacgtcg
   139621 cttggaggaa aatcctcttc gtgtcttgga ctctaaggaa aaagaagaca aggtggcagt
   139681 agagaatgcg ccgtctatct tggactttct tgatgaagaa agccaaactc attttgatgc
   139741 tgtgcgtcag atgttggaaa atcttggagt agattacatc atcgatacca atatggtgcg
   139801 tggtctggac tactacaacc acaccatttt cgagtttatc acagagattg agggcaatga
   139861 cttgacagtc tgtgcgggtg gtcgctacga tggtttggtt gcttactttg gaggccctga
   139921 aactgctgga tttggttttg gacttggtgt agagcgcctg cttctcatcc ttgaaaaaca
   139981 aggcgtgacc ctccctatcg aaaacgccct agatgtctat atcgcagtct tgggcgaagg
   140041 ggcaaatatc aaggccttgg aattggtaca ggctcttcgc caacaaggtt tcaaagcaga
   140101 gcgtgattac ctcaaccgta aactaaaagc tcagttcaag tcagccgatg tctttgtggc
   140161 taagaccctc atcaccctag gagagagcga agtcgaaagc ggacaagtga cggtcaagaa
   140221 caaccaaacc cgagaagaag tgcaagtgtc acttgagaca atcagccaaa acttctcaga
   140281 aatctttgaa aaactaggat tttatactca ataaaaatca aagagcaaac taggaagcta
   140341 gccgcaggtt gctcaaaaca ctgttttgag gttgtagatg aaactgacga agtcagtaac
   140401 catacctacg gcaaggtgaa actgacgtgg tttgaagaga ttttagaaga gtattaatga
   140461 tagataaagt ggtcaggaac ctactcctga cctttttctt ttgcaaaatg acaaaaatca
   140521 taaacttttt gacaactata attgtcaaaa agaaaaagat atgttacaat gaattcaagt
   140581 taagaaatag gaagcagaaa ggagttataa tgtgggtact aggatttata ctatttatga
   140641 ttttctttta ttctaataat tctaaaaaaa tcaagaaact agagaagaaa atcaaaagac
   140701 ttgagcgaaa agagaaagga aatgcagaaa tgtcgagatt attacaagaa atgattggaa
   140761 aggaaccaat tataacggga gtgtatattg ggccagataa ctgggaagtt gtggatgttg
   140821 atgaggaatg ggtaaagcta cgacgtgtag ataatacggg aaaagaaaaa ttcaagttgc
   140881 aacgtattga ggatatccaa accgttgaat ttgacggaga gtaggtgtgt aacatgcaac
   140941 taaaaaatcg tctaaaagag cttcgagctc gcgatggtct caatcaaacc gacctagcca
   141001 aactggcagg ggtttccaga cagaccatta gcctactaga acgggatgag tacaccccat
   141061 ccattatcat tgccctgaaa atatctcaaa ttttcaacga aacagtcgaa tcggtatttc
   141121 gtttggagga ggacgagtga tgaacaagta taaagtgatt tattatgtag tggtcatagc
   141181 tttattagtc agcgtatttc tactgattgg gatggaccta agctggttta atccctatca
   141241 aagcgaccaa tttgtttggg tctactttgc tctcatccca gtaattgaat ggattgaaaa
   141301 gaaatccaaa aatctagcaa gtgaaaaagg agaatgaata tgaaaaagaa acgtagattg
   141361 ttatttttga tgtctattgt cttggggggg ttcttgggca tgtttgtagg gatgtttaag
   141421 gcacgtgtcg aatcccacga aattatttta gatgtaaaag ccttgatgcc atggatatca
   141481 gctatttgtt tactgatagg tttcattagt atgtttttga ctttcaattt cttaaagaaa
   141541 agcagaaaat ttcattcctt gtatcaagag gaaatggatg acgatctgaa tgaaacctat
   141601 tatgtgcaaa tgtatcggaa tcttgagttt ggaaccattg cttttaatat tacaggtgta
   141661 gcgattccat tggctatttt tatttcatta agtgaggtga ttatattgca tacaaaccct
   141721 caaacatttt tcctttcttt cttactcttt gtggtattct tagtcgctca aaaatctctt
   141781 tttaaaacca ttgcgattgt tcgtcagttt gatttggaat ttttcgctac accaaaggat
   141841 gtcttgaact atataaattc ttatgatgaa ggggagcgtc aggctaattt ggaacagagt
   141901 tttcgaattt tattccaatt acaccaatat gtcttaccag ccttatatat ttttcttatt
   141961 atcatttctt tcttgacagg agagattcag ttactagctt tcttgcttgt aggagccatc
   142021 catgtttata tcaatgtgat gcagttacct atggtaaaac gttatttcaa ataaaggagt
   142081 tatctatgaa actacttaaa aaccttggct ggtttcttct agcccttcta tcctttttct
   142141 ttatctatgg ctttattcag gggctcgcga ctgcgtcgct tgctttaggc gcttcaccct
   142201 atgctgttac tctactctat gtggtcttgg ctggagtata tgtgtacggc atttacaaat
   142261 ggtatcagaa agctcctgtt tatattgaga agagcggctt taaccgattt atttggcttc
   142321 ctgccttggt ttggttctta tctctggtcg ttcaattctt cttgccagat gatccttcag
   142381 taaatcaaca aatagcgaca gacttgacct tgtctcaacc acttttctca ttctttgctg
   142441 tggttatttt tgctcctttg acggaagaga ttgtttttag agggatgtta gcacgctatc
   142501 tctttcctaa gcaggacaat agtaaacgaa ccctgatttt tcttctggta tctagtcttc
   142561 tatttgcctt gattcatttt ccaggtgatg tgcaacaatt ttttgtctat tttagccttg
   142621 gttttagttt gggtttggct tacattagca gaaaaggtct ggtctacagt atttctcttc
   142681 acgctttgaa taatttagtc ggctttttga tgattctcat gctataatag agtcaggagg
   142741 tcacatgaaa cgagtaattt tattagcagt gattcaggca gtcgttctat ttttcatcat
   142801 tggagcgcta gcttatgcct tcaaaggcga tttcttctat aactatctag cagttgtctt
   142861 tgctcctatt gcaggtgtac tgcgttttgg gacggcttac ataacggaaa ttgtcttgcc
   142921 tcgaaaggca gccgaaatcg ctgaaaagcg taaagcaggc aaaaattcaa aataaaagag
   142981 tccggtgaag ttcatcggat ttttgtatta tactcaatga aaatcaaaga gcaaactagg
   143041 aagctagccg caggttgctc aaaacactgt tttgaggttg t
//
LOCUS       DAVHSH010000002       104545 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000002 DAVHSH010000000
VERSION     DAVHSH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 104545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.002"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            212..868
                     /locus_tag="VVR08_000134"
     CDS             212..868
                     /locus_tag="VVR08_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU6074114.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            858..1181
                     /locus_tag="VVR08_000135"
     CDS             858..1181
                     /locus_tag="VVR08_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU6074115.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1285..2115
                     /locus_tag="VVR08_000136"
     CDS             1285..2115
                     /locus_tag="VVR08_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6074116.1"
                     /translation="MKKIVKYSSLAALGLVAAGLLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2269..3123
                     /locus_tag="VVR08_000137"
     CDS             2269..3123
                     /locus_tag="VVR08_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6074117.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3223..4596
                     /locus_tag="VVR08_000138"
     CDS             3223..4596
                     /locus_tag="VVR08_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU6074118.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4589..5650
                     /locus_tag="VVR08_000139"
     CDS             4589..5650
                     /locus_tag="VVR08_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU6074119.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVTANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5652..6344
                     /locus_tag="VVR08_000140"
     CDS             5652..6344
                     /locus_tag="VVR08_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074120.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6374..6943)
                     /locus_tag="VVR08_000141"
     CDS             complement(6374..6943)
                     /locus_tag="VVR08_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6074121.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7078..7692
                     /locus_tag="VVR08_000142"
     CDS             7078..7692
                     /locus_tag="VVR08_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6074122.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFISSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7694..9340
                     /locus_tag="VVR08_000143"
     CDS             7694..9340
                     /locus_tag="VVR08_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6074123.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9352..10638
                     /locus_tag="VVR08_000144"
     CDS             9352..10638
                     /locus_tag="VVR08_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074124.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATAGHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVASVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10690..11223
                     /locus_tag="VVR08_000145"
     CDS             10690..11223
                     /locus_tag="VVR08_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074125.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11301..11771
                     /gene="nrdI"
                     /locus_tag="VVR08_000146"
     CDS             11301..11771
                     /gene="nrdI"
                     /locus_tag="VVR08_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU6074126.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12064..13326)
                     /locus_tag="VVR08_000147"
     CDS             complement(12064..13326)
                     /locus_tag="VVR08_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU6074127.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13636..14094)
                     /locus_tag="VVR08_000148"
     CDS             complement(13636..14094)
                     /locus_tag="VVR08_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU6074128.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14091..14531)
                     /locus_tag="VVR08_000149"
     CDS             complement(14091..14531)
                     /locus_tag="VVR08_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074129.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14887..16836
                     /gene="mutL"
                     /locus_tag="VVR08_000150"
     CDS             14887..16836
                     /gene="mutL"
                     /locus_tag="VVR08_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU6074130.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMALVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTFYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17161..17628)
                     /locus_tag="VVR08_000151"
     CDS             complement(17161..17628)
                     /locus_tag="VVR08_000151"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU6074131.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17629..18834)
                     /locus_tag="VVR08_000152"
     CDS             complement(17629..18834)
                     /locus_tag="VVR08_000152"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU6074132.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18854..19489)
                     /gene="ribE"
                     /locus_tag="VVR08_000153"
     CDS             complement(18854..19489)
                     /gene="ribE"
                     /locus_tag="VVR08_000153"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU6074133.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19474..20574)
                     /gene="ribD"
                     /locus_tag="VVR08_000154"
     CDS             complement(19474..20574)
                     /gene="ribD"
                     /locus_tag="VVR08_000154"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU6074134.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20708..20822)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20979..21572
                     /gene="ruvA"
                     /locus_tag="VVR08_000155"
     CDS             20979..21572
                     /gene="ruvA"
                     /locus_tag="VVR08_000155"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU6074135.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21582..22145
                     /locus_tag="VVR08_000156"
     CDS             21582..22145
                     /locus_tag="VVR08_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU6074136.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWRGLK"
     gene            22142..22819
                     /locus_tag="VVR08_000157"
     CDS             22142..22819
                     /locus_tag="VVR08_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6074137.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKGIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22956..23987)
                     /locus_tag="VVR08_000158"
     CDS             complement(22956..23987)
                     /locus_tag="VVR08_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU6074138.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLRLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24242..24925)
                     /locus_tag="VVR08_000159"
     CDS             complement(24242..24925)
                     /locus_tag="VVR08_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU6074139.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPNMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24937..25881)
                     /locus_tag="VVR08_000160"
     CDS             complement(24937..25881)
                     /locus_tag="VVR08_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6074140.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26013..28844
                     /gene="uvrA"
                     /locus_tag="VVR08_000161"
     CDS             26013..28844
                     /gene="uvrA"
                     /locus_tag="VVR08_000161"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU6074141.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28837..29898
                     /locus_tag="VVR08_000162"
     CDS             28837..29898
                     /locus_tag="VVR08_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6074142.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30030..30428
                     /gene="spx"
                     /locus_tag="VVR08_000163"
     CDS             30030..30428
                     /gene="spx"
                     /locus_tag="VVR08_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU6074143.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30494..31063
                     /locus_tag="VVR08_000164"
     CDS             30494..31063
                     /locus_tag="VVR08_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6074144.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31150..31416
                     /locus_tag="VVR08_000165"
     CDS             31150..31416
                     /locus_tag="VVR08_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU6074145.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31420..31839
                     /gene="ruvX"
                     /locus_tag="VVR08_000166"
     CDS             31420..31839
                     /gene="ruvX"
                     /locus_tag="VVR08_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU6074146.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31855..32160
                     /locus_tag="VVR08_000167"
     CDS             31855..32160
                     /locus_tag="VVR08_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU6074147.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32419..33669
                     /locus_tag="VVR08_000168"
     CDS             32419..33669
                     /locus_tag="VVR08_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6074148.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33666..34211
                     /locus_tag="VVR08_000169"
     CDS             33666..34211
                     /locus_tag="VVR08_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU6074149.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            34357..35889
                     /gene="cls"
                     /locus_tag="VVR08_000170"
     CDS             34357..35889
                     /gene="cls"
                     /locus_tag="VVR08_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU6074150.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36147..37685
                     /locus_tag="VVR08_000171"
     CDS             36147..37685
                     /locus_tag="VVR08_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6074151.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFVIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37805..40012
                     /gene="nrdD"
                     /locus_tag="VVR08_000172"
     CDS             37805..40012
                     /gene="nrdD"
                     /locus_tag="VVR08_000172"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU6074152.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALYKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40024..40164
                     /locus_tag="VVR08_000173"
     CDS             40024..40164
                     /locus_tag="VVR08_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074153.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40208..40714
                     /locus_tag="VVR08_000174"
     CDS             40208..40714
                     /locus_tag="VVR08_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074154.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            40707..41297
                     /gene="nrdG"
                     /locus_tag="VVR08_000175"
     CDS             40707..41297
                     /gene="nrdG"
                     /locus_tag="VVR08_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU6074155.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41294..41911
                     /locus_tag="VVR08_000176"
     CDS             41294..41911
                     /locus_tag="VVR08_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU6074156.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42177..42485
                     /gene="rpsJ"
                     /locus_tag="VVR08_000177"
     CDS             42177..42485
                     /gene="rpsJ"
                     /locus_tag="VVR08_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU6074157.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42701..43327
                     /gene="rplC"
                     /locus_tag="VVR08_000178"
     CDS             42701..43327
                     /gene="rplC"
                     /locus_tag="VVR08_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU6074158.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43352..43975
                     /gene="rplD"
                     /locus_tag="VVR08_000179"
     CDS             43352..43975
                     /gene="rplD"
                     /locus_tag="VVR08_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU6074159.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            43975..44271
                     /locus_tag="VVR08_000180"
     CDS             43975..44271
                     /locus_tag="VVR08_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU6074160.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44289..45122
                     /gene="rplB"
                     /locus_tag="VVR08_000181"
     CDS             44289..45122
                     /gene="rplB"
                     /locus_tag="VVR08_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU6074161.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45226..45507
                     /gene="rpsS"
                     /locus_tag="VVR08_000182"
     CDS             45226..45507
                     /gene="rpsS"
                     /locus_tag="VVR08_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU6074162.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45519..45863
                     /gene="rplV"
                     /locus_tag="VVR08_000183"
     CDS             45519..45863
                     /gene="rplV"
                     /locus_tag="VVR08_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU6074163.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45876..46529
                     /gene="rpsC"
                     /locus_tag="VVR08_000184"
     CDS             45876..46529
                     /gene="rpsC"
                     /locus_tag="VVR08_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU6074164.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46533..46946
                     /gene="rplP"
                     /locus_tag="VVR08_000185"
     CDS             46533..46946
                     /gene="rplP"
                     /locus_tag="VVR08_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU6074165.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46956..47162
                     /locus_tag="VVR08_000186"
     CDS             46956..47162
                     /locus_tag="VVR08_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU6074166.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47187..47447
                     /gene="rpsQ"
                     /locus_tag="VVR08_000187"
     CDS             47187..47447
                     /gene="rpsQ"
                     /locus_tag="VVR08_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU6074167.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47473..47841
                     /gene="rplN"
                     /locus_tag="VVR08_000188"
     CDS             47473..47841
                     /gene="rplN"
                     /locus_tag="VVR08_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU6074168.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47919..48224
                     /gene="rplX"
                     /locus_tag="VVR08_000189"
     CDS             47919..48224
                     /gene="rplX"
                     /locus_tag="VVR08_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU6074169.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48248..48790
                     /gene="rplE"
                     /locus_tag="VVR08_000190"
     CDS             48248..48790
                     /gene="rplE"
                     /locus_tag="VVR08_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU6074170.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48808..49077
                     /gene="rpsN"
                     /locus_tag="VVR08_000191"
     CDS             48808..49077
                     /gene="rpsN"
                     /locus_tag="VVR08_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU6074171.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49362..49760
                     /gene="rpsH"
                     /locus_tag="VVR08_000192"
     CDS             49362..49760
                     /gene="rpsH"
                     /locus_tag="VVR08_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU6074172.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGSNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49952..50488
                     /gene="rplF"
                     /locus_tag="VVR08_000193"
     CDS             49952..50488
                     /gene="rplF"
                     /locus_tag="VVR08_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU6074173.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50572..50928
                     /gene="rplR"
                     /locus_tag="VVR08_000194"
     CDS             50572..50928
                     /gene="rplR"
                     /locus_tag="VVR08_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU6074174.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50946..51440
                     /gene="rpsE"
                     /locus_tag="VVR08_000195"
     CDS             50946..51440
                     /gene="rpsE"
                     /locus_tag="VVR08_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU6074175.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51412..51636
                     /gene="rpmD"
                     /locus_tag="VVR08_000196"
     CDS             51412..51636
                     /gene="rpmD"
                     /locus_tag="VVR08_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU6074176.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            51781..52221
                     /gene="rplO"
                     /locus_tag="VVR08_000197"
     CDS             51781..52221
                     /gene="rplO"
                     /locus_tag="VVR08_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU6074177.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52234..53544
                     /gene="secY"
                     /locus_tag="VVR08_000198"
     CDS             52234..53544
                     /gene="secY"
                     /locus_tag="VVR08_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU6074178.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKINPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53695..54333
                     /locus_tag="VVR08_000199"
     CDS             53695..54333
                     /locus_tag="VVR08_000199"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU6074179.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNSDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54450..54668
                     /gene="infA"
                     /locus_tag="VVR08_000200"
     CDS             54450..54668
                     /gene="infA"
                     /locus_tag="VVR08_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU6074180.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54693..54809
                     /gene="rpmJ"
                     /locus_tag="VVR08_000201"
     CDS             54693..54809
                     /gene="rpmJ"
                     /locus_tag="VVR08_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU6074181.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54827..55192
                     /gene="rpsM"
                     /locus_tag="VVR08_000202"
     CDS             54827..55192
                     /gene="rpsM"
                     /locus_tag="VVR08_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU6074182.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55210..55593
                     /gene="rpsK"
                     /locus_tag="VVR08_000203"
     CDS             55210..55593
                     /gene="rpsK"
                     /locus_tag="VVR08_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU6074183.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55636..56571
                     /locus_tag="VVR08_000204"
     CDS             55636..56571
                     /locus_tag="VVR08_000204"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU6074184.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56583..56969
                     /gene="rplQ"
                     /locus_tag="VVR08_000205"
     CDS             56583..56969
                     /gene="rplQ"
                     /locus_tag="VVR08_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU6074185.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57234..57500
                     /locus_tag="VVR08_000206"
     CDS             57234..57500
                     /locus_tag="VVR08_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU6074186.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57510..58847
                     /locus_tag="VVR08_000207"
     CDS             57510..58847
                     /locus_tag="VVR08_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU6074187.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59091..59783
                     /locus_tag="VVR08_000208"
     CDS             59091..59783
                     /locus_tag="VVR08_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6074188.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59886..61531)
                     /locus_tag="VVR08_000209"
                     /pseudo
     CDS             complement(59886..61531)
                     /locus_tag="VVR08_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(61521..62612)
                     /locus_tag="VVR08_000210"
     CDS             complement(61521..62612)
                     /locus_tag="VVR08_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074189.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLGLMQIAQYADRKPDKLSGGQQQRVTLACVLAVNPSVLLMDEP
                     LSNLEAKLRLDTRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KKLYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMPALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTDYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(62625..63746)
                     /locus_tag="VVR08_000211"
                     /pseudo
     CDS             complement(62625..63746)
                     /locus_tag="VVR08_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(63963..64160)
                     /locus_tag="VVR08_000212"
     CDS             complement(63963..64160)
                     /locus_tag="VVR08_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6074190.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKHLHISPKELKLLGRIVK"
     gene            complement(64235..65011)
                     /locus_tag="VVR08_000213"
     CDS             complement(64235..65011)
                     /locus_tag="VVR08_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU6074191.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            65133..65879
                     /locus_tag="VVR08_000214"
     CDS             65133..65879
                     /locus_tag="VVR08_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6074192.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65892..66872
                     /locus_tag="VVR08_000215"
     CDS             65892..66872
                     /locus_tag="VVR08_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU6074193.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYSLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67067..67387
                     /locus_tag="VVR08_000216"
     CDS             67067..67387
                     /locus_tag="VVR08_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6074194.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67433..67741
                     /locus_tag="VVR08_000217"
     CDS             67433..67741
                     /locus_tag="VVR08_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6074195.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67758..69056
                     /locus_tag="VVR08_000218"
     CDS             67758..69056
                     /locus_tag="VVR08_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6074196.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSMTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFVAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLAYQNEIKQS"
     gene            69207..71645
                     /locus_tag="VVR08_000219"
     CDS             69207..71645
                     /locus_tag="VVR08_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU6074197.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71664..72332
                     /locus_tag="VVR08_000220"
     CDS             71664..72332
                     /locus_tag="VVR08_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU6074198.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            72350..73438
                     /locus_tag="VVR08_000221"
     CDS             72350..73438
                     /locus_tag="VVR08_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU6074199.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73893..76394
                     /locus_tag="VVR08_000222"
     CDS             73893..76394
                     /locus_tag="VVR08_000222"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU6074200.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVANYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEEA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTRADGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            76588..77283
                     /locus_tag="VVR08_000223"
     CDS             76588..77283
                     /locus_tag="VVR08_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074201.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            77295..77711
                     /locus_tag="VVR08_000224"
     CDS             77295..77711
                     /locus_tag="VVR08_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074202.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQTEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLSSYQRQGIGSSLMKQALGNFKEAYQVQ
                     LATEQTEKNVGFNRSMGFEILSTYNWIGMTWMNRKK"
     gene            complement(78526..78618)
                     /locus_tag="VVR08_000225"
     CDS             complement(78526..78618)
                     /locus_tag="VVR08_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU6074203.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            78779..79750
                     /gene="ruvB"
                     /locus_tag="VVR08_000226"
     CDS             78779..79750
                     /gene="ruvB"
                     /locus_tag="VVR08_000226"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU6074204.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            79839..80303
                     /locus_tag="VVR08_000227"
     CDS             79839..80303
                     /locus_tag="VVR08_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU6074205.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            80534..81292
                     /locus_tag="VVR08_000228"
     CDS             80534..81292
                     /locus_tag="VVR08_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU6074206.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            81301..82104
                     /locus_tag="VVR08_000229"
     CDS             81301..82104
                     /locus_tag="VVR08_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU6074207.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            82126..83385
                     /gene="rseP"
                     /locus_tag="VVR08_000230"
     CDS             82126..83385
                     /gene="rseP"
                     /locus_tag="VVR08_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU6074208.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            83398..85251
                     /locus_tag="VVR08_000231"
     CDS             83398..85251
                     /locus_tag="VVR08_000231"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU6074209.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     SDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            85350..86729
                     /gene="bglA"
                     /locus_tag="VVR08_000232"
     CDS             85350..86729
                     /gene="bglA"
                     /locus_tag="VVR08_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6074210.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            86921..88729
                     /gene="glmS"
                     /locus_tag="VVR08_000233"
     CDS             86921..88729
                     /gene="glmS"
                     /locus_tag="VVR08_000233"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU6074211.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDLEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVYPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            88848..89897
                     /locus_tag="VVR08_000234"
     CDS             88848..89897
                     /locus_tag="VVR08_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU6074212.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(89997..93839)
                     /gene="spuA"
                     /locus_tag="VVR08_000235"
     CDS             complement(89997..93839)
                     /gene="spuA"
                     /locus_tag="VVR08_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU6074213.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGTSLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDATSIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            94256..94669
                     /gene="rpsL"
                     /locus_tag="VVR08_000236"
     CDS             94256..94669
                     /gene="rpsL"
                     /locus_tag="VVR08_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU6074214.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            94689..95159
                     /gene="rpsG"
                     /locus_tag="VVR08_000237"
     CDS             94689..95159
                     /gene="rpsG"
                     /locus_tag="VVR08_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU6074215.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            95584..97665
                     /gene="fusA"
                     /locus_tag="VVR08_000238"
     CDS             95584..97665
                     /gene="fusA"
                     /locus_tag="VVR08_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU6074216.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            97769..102160
                     /locus_tag="VVR08_000239"
     CDS             97769..102160
                     /locus_tag="VVR08_000239"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU6074217.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            102262..102525
                     /locus_tag="VVR08_000240"
     CDS             102262..102525
                     /locus_tag="VVR08_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU6074218.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            102518..102796
                     /locus_tag="VVR08_000241"
     CDS             102518..102796
                     /locus_tag="VVR08_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU6074219.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            102817..102969
                     /locus_tag="VVR08_000242"
     CDS             102817..102969
                     /locus_tag="VVR08_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074220.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            102991..104232
                     /locus_tag="VVR08_000243"
     CDS             102991..104232
                     /locus_tag="VVR08_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU6074221.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            104242..104472
                     /locus_tag="VVR08_000244"
     CDS             104242..104472
                     /locus_tag="VVR08_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6074222.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT        31123 a        19279 c        23336 g        30807 t
ORIGIN      
        1 gatggtcaaa atcaacagac ttttttctct tttctgaatg tgttatagta gactgaatct
       61 aaaatagtac gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga
      121 tttgttcata tcttatttca atccattata ttaagacaat atgaggagaa agatgaaaga
      181 aaaaggattt taggaggggg tgcaggcagt catgccaacg gctcttggtt atgtcagtat
      241 cggcctggcc tgtggaatta tcggtgcgcc ctatgtgaca cctgttgaga tgggcttgat
      301 gagtctcttt gtttatgctg ggagtgccca gtttgccatg ttggcactga ttgtggttca
      361 agctcctgtg gcagctattg ctatgacggt ttttctaatc aacttgcgtc tctttttgtt
      421 gagtttacac gcatcgactt atttccgtca taccagtctt tggtacaata tcggtatgtc
      481 tagtatcttg acagatgaga cctatggcgt tttgatgggt gaattggccc atacagacaa
      541 ggtaaatcct atgtggatgc acggaaacaa tcttaacagc tatgtggctt ggtttgtggg
      601 gacagtagtc ggaacggctc tgggtggcct gctaccaaat ccagaaatct ttggcttgga
      661 ttttgccctg gttgggatgt ttattggtat ttttgcttcg caatttcaga ttatgcaaag
      721 acggattcct gtccgcaatc tgctcattat cctagcagtt gttgcggtgt ccttcttttt
      781 gctcttgaca gtggtgtctc agtcactagc tgttctgttt gcgacgctac ttggttgtag
      841 catgggggtg gttttagatg gtcagtaagt atcttttatt agcagttatt ttctctggct
      901 tggtgacttg gattctccgt atgattccct tcatcttagt caagtataag ggcttgcctg
      961 caatcgttga gcgttttttg aagttcttgc ccgtttccat tatctttgcc ttgattcttt
     1021 caagcgtagt gacaggtaag gttgggagcc ttcctcaaat taaatggcta gacttcttag
     1081 ccgtctttcc aacagcttgg gtagcctttc gctaccgcaa tctagtcggt acggttctct
     1141 ttggagtggt cttgattgcc atcttgcgtt tggtctttta aattacccat aaaaaaaact
     1201 tatcacagag atagatatca tataatggcg taaatgctct ttttctgtta agattataag
     1261 gtattctatt ttggaggaaa tgacatgaaa aaaatcgtta aatactcatc tcttgctgcc
     1321 ctaggacttg ttgctgcagg tttgcttgcg gcttgctcag ggggtgctaa gaaagaagga
     1381 gaagcagcta gcaagaaaga aatcatcgtt gcaaccaatg gatcaccaag gccatttata
     1441 tatgaagaaa atggcgaatt gactggttac gagattgaag tcgttcgcgc tatctttaaa
     1501 gattctgaca aatatgatgt caagtttgaa aagacagaat ggtcaggtgt ctttgctggt
     1561 cttgacgctg accgttacaa tatggctgtc aacaatctta gctacactaa agaacgtgcg
     1621 gagaaatacc tctatgccgc accaattgcc caaaatccta atgtccttgt cgtgaagaaa
     1681 gatgactcta gtatcaagtc tctcgatgat atcggtggaa aatcgacgga agtcgttcaa
     1741 gccactacat cagctaagca gttagaagca tacaatgctg aacacacgga caacccaact
     1801 atccttaact atactaaggc agacttccaa caaatcatgg tacgtttgag cgatggacaa
     1861 tttgactaca agatttttga taaaatcggt gttgaaacag tgatcaagaa ccaaggtttg
     1921 gacaacttga aagttatcga acttccaagc gaccaacaac cgtacgttta cccacttctt
     1981 gctcaaggtc aagatgagtt gaaatcattt gtagacaaac gcattaaaga actctacaaa
     2041 gacggaacgc ttgaaaaatt gtctaaacaa ttcttcggag acacttacct accggcagaa
     2101 gctgatatta aataatttct tgaaatcatc cattctgagt aagatgggtg gtttctcagt
     2161 ttttagggat atagttttaa actatatatc tgactatcta ataacaattt gtgaaatcaa
     2221 acaaattgtg agatactagt acggtattat ttttaaggag aaagaatcat gaaaatcaaa
     2281 aaatggcttg gcctagcagc ccttgctaca gtcgcaggtt tggctcttgc agcttgcgga
     2341 aactcagaaa agaaagcaga caatgcaaca actatcaaaa tcgcaactgt taaccgtagc
     2401 ggttctgaag aaaaacgttg ggacaaaatc caagaattgg ttaaaaaaga cggaattacc
     2461 ttggaattta cagagttcac agactactca caaccaaaca aagcaactgc tgatggcgaa
     2521 gtagatttga acgctttcca acactataac ttcttgaaca actggaacaa agaaaacgga
     2581 aaagaccttg tagcgattgg agatacttac atctctccaa tccgccttta ctcaggtttg
     2641 aatggaagtg ccaacaagta cactaaagta gaagacatcc cagcaaacgg agaaatcgct
     2701 gtaccgaatg acgctacaaa cgaaagccgt gcgctttact tgcttcaatc agctggcttg
     2761 attaaattgg atgtttctgg aactgctctt gcaacagttg ccaacatcaa agaaaatcca
     2821 aagaacttga aaatcactga attggacgct agccaaacag ctcgttcatt gtcatcagtt
     2881 gacgctgccg ttgtaaacaa taccttcgtt acagaagcaa aattggacta caagaaagca
     2941 cttttcaaag aacaagctga tgaaaactca aaacaatggt acaacatcat tgttgcgaaa
     3001 aaagattggg aaacatcacc taaggctgat gctatcaaga aagtaatcgc agcttaccac
     3061 acagatgacg tgaaaaaagt tatcgaagaa acatcagacg gtttggatca accagtttgg
     3121 taataagaaa cagggaggtg ggagagagaa ttccacctct tgcttttgta tagagcacgg
     3181 agtgtaaaga agattattcg ttcatagaaa ggtagagaga atatggtttt tcctagcgaa
     3241 caagaacaga ttgaaaaatt tgaaaaggat catgtagccc agcattattt tgaggttttg
     3301 cgtaccttga tttctaagaa atcagtcttt gcccagcagg ttggactcaa ggaagtcgca
     3361 aactatctgg gtgagatttt caagcgtgtt ggagctgaag tggagattga tgagagctat
     3421 acagcgccct ttgtcatggc acatttcaag agttcgcgtc cagatgccaa gaccttgatt
     3481 ttctataacc actatgacac tgtgccagcg gatggggatc aggtctggac agaggatcct
     3541 tttacgcttt cggtccgcaa tggcttcatg tatgggcgtg gggttgatga cgacaagggt
     3601 catatcacag ctcgcttgag tgctttgaga aaatatatgc agcaccatga tgatttacct
     3661 gtcaatatca gctttatcat ggagggagcg gaggaatcgg cttcaacaga cctagataag
     3721 tatttggaaa agcatgcaga caaactccgt ggggcggatt tgttggtctg ggaacaaggg
     3781 accaaaaatg ccttggaaca gctggaaatt tctggtggca ataaggggat tgtgaccttt
     3841 gatgccaagg taaaaagcgc tgatgtggat atccactcga gttatggtgg tgttgtggaa
     3901 tcagctcctt ggtatctcct ccaagcctta cagtctcttc gtgctgcgga tggccgtatc
     3961 ttggttgaag gcttgtacga agaagtacaa gagcccaatg aacgagaaat ggccttgcta
     4021 gaaacttatg gtcaacgaaa cccagaggaa gttagtcgga tttatggatt ggagttgcct
     4081 ctcttacagg aggagcggat ggcctttcta aaacgtttct ttttcgatcc agcgcttaat
     4141 atcgaaggaa tccagtctgg ttatcaaggt cagggtgtta agactatttt acctgcagaa
     4201 gccagtgcca agctagaggt tcgtctggtt ccgggcctag aaccgcatga tgttctggaa
     4261 aaaattcgga aacagctaga caaaaatggc tttgataagg tagaattata ctataccttg
     4321 ggagagatga gctatcgaag cgatatgagc gcaccagcca ttctcaatgt gatcgagttg
     4381 gccaagaaat tctatccaca gggcgtttca gtcttgccga cgacagcggg gacaggacct
     4441 atgcatacgg tctttgatgc cctagaggta ccaatggttg cattcggtct aggaaatgcc
     4501 aatagccgag accacggtgg agatgaaaat gtgcgaatcg ctgattatta cacccatatc
     4561 gaattagtag aggagctgat tagaagctat gagtagagat attatcaagt tagatcagat
     4621 cgatgtgact tttcaccaaa agaagagaac catcacagcg gttaaggatg tgaccattca
     4681 catccaagaa ggggatatct acggaatcgt tggatattct ggagcaggaa aatcaaccct
     4741 tgtacgggtg attaatctct tgcaaaaacc atctgcaggg aaaattacca ttgacgacga
     4801 tgtgattttt gacggcaagg tgaccttgac ggcagagcag ttgcgtcgta aacgtcaaga
     4861 tatcggaatg attttccagc attttaacct gatgagccaa aagacagcag aggagaatgt
     4921 agcctttgcc cttaaacact ctgaactcag caaggaagaa aagaaggcta aagtagctaa
     4981 gttgttggac ttggttggtt tggcagatcg tgctgaaaac tacccttcac aactatctgg
     5041 agggcaaaaa cagcgtgtgg caattgcgcg tgccttggcc aatgatccaa aaatcttgat
     5101 ttcagacgag tcaacttctg cccttgatcc gaagacaacc aagcagattt tggccttgtt
     5161 gcaagatttg aaccaaaaat taggcttgac tgttgtcttg attacgcatg aaatgcagat
     5221 tgtcaaagac attgccaacc gtgtggcggt tatgcaggat gggcatttga ttgaagaggg
     5281 tagtgtgctt gaaatcttct cagaccctaa acaacctttg actcaagact ttatctcaac
     5341 agctacaggt attgacgaag ccatggtcaa aatcgagaag caagaaatcg tggaacactt
     5401 gtctgaaaac agtctcttgg tgcaactcaa gtacgctgga tcttcaacag acgagccact
     5461 tttgaatgaa ttgtacaagc attatcaagt aacggctaat attctctatg ggaatatcga
     5521 aatcctcgat ggtactcctg ttggagaatt ggtggtggtc ttgtcaggtg aaaaagcagc
     5581 gttggcaggt gcccaagaag ccattcgtca agcaggtgta caactaaagg tattgaaggg
     5641 aggacagtaa gatggaatca ttgattcaaa cctatttacc aaatgtctat aaaatgggtt
     5701 gggctggtca ggcaggctgg ggaacggcta tctacttaac tctttatatg acagttcttt
     5761 ccttcattat cggaggcttc ttggggctag tggcaggtct ctttctcgtc ttgacagcgc
     5821 caggtggtgt cttggagaat aaagtcgtat tctggatttt agacaaaatt acctcaattt
     5881 ttcgtgcggt tccctttatc atcctcttgg caatcttgtc accactttct cacttgattg
     5941 ttaaaacaag tatcgggcca aatgcagccc ttgtcccact ttcttttgca gtctttgcct
     6001 tctttgcccg tcaggtgcag gttgtcttgg ctgaattgga tggcggtgtc attgaggcgg
     6061 ctcaagcgag cggagcgact ttctgggaca tcgtgggtgt ttacctatca gaaggtcttc
     6121 cagatttgat ccgtgtgacg actgtgacct tgatttccct tgttggggaa acagctatgg
     6181 ccggtgcggt tggagctggt ggtatcggta acgtagccat cgcttatgga tttaaccgct
     6241 acaatcacga tgtgaccatc ttggcaacca ttattatcat tttgattatc tttgcaatcc
     6301 aattcttggg agatttcttg actaagaaat tgagccataa ataaaaaaga gccgcgtggc
     6361 tctttttaac tgatcagatt ttctgtgcaa attttttact caaggcttgt ccaatcaagg
     6421 cacccactag ggctccgatg acaatacttg cgataaatag aaggacagtt ccagggtttg
     6481 gagcgaccat gatacggtcg atatattctt gggattttcc tcttgccaga agagtagcca
     6541 tataggcttt gggcgcaatc cacataagca agattggtcc tgttgtacta aaggcgaaaa
     6601 taatgaaaga aaggaagttc tttgttttgt ccttgtattt tcctaaatga gctactccat
     6661 ctgctaggag gccacagata attccaggaa ggaaggaacc agcaccgtgt ttagttccca
     6721 agaaaaagag ggcaatgaca aggccgatag tggtaatggc tccaaagcgc ggaacttttg
     6781 cgactaggat catatagacg ctaccgccga caagggcagt aaaggcaggc gcataaaaca
     6841 tgtttcccgt ttggtcaaag agattgccca aaaggacacc aatccccatg cagaggaagt
     6901 aaagaactgc aaaaagcagt gtagttaaga tagatttctt catgaattgt ctcctgataa
     6961 ttttttcaca attctcattt taccatggtt tggtgggatt gtaaatggat actagaagtt
     7021 tttgaaaacg cttgaaatat gatataatgg tttcatagtt atttttaggg gaatatcatg
     7081 ggtagatttt tagactttgt ctttaatcgt ttctttttag ggatgattgc gacagccttc
     7141 ttttggctat taactttagc aggagggatt atccttggtc tagcgccggc tagtgccacc
     7201 ttgatgagct tatatgcaga acatggttat agctttcggg aatacagttt gaaggaggct
     7261 tggtctcttt acaagcaaaa ttttatctca agcaacctga ttttctatag ctttttaggt
     7321 gtgggtctag ttttgaccta tggtttgtat ctcttggtgc aattgcctca tcagaccatt
     7381 gttcatttga ttgcgaccct tttgaatgtc ctagtagttg ccctgatctt tttggcttat
     7441 acagtatctt taaaattaca agtttatttt gccttgtcct atcgaaatag tctcaaatta
     7501 tccttgattg gcatctttat gagtctagca gctgtggcca aggttctcct tgggactgtg
     7561 ctacttgtag caattggtta ctatatgcct gccctgctat tttttgtagg aattgggatg
     7621 tggcatttct ttatcagtga tatgttggaa cctgtctatg aaatcatcca tgaaaaattg
     7681 gcgacaaaat agaatgaagc acttttggct acatacgctt ctaagaacct atagttcagt
     7741 gatgatcatt atcattgcga gttttgcaat cttactctct tacgctgact gggattcacg
     7801 tgaaaaggaa gcccagagag tagcccagcg tgtaactgct agaacagtga gtgaaattga
     7861 atattaccat agagagtcaa cccagatagc tcaggcttta gttgaaaatc aagctcgtat
     7921 tgagggaatc tataaatact ttagccttag catgccagac tatttttact ggcaattaga
     7981 gcggaaagct tcgccttata tatcagtctc tctgtatgaa aatgttgatg acctctatgt
     8041 tcgaaatgat tttgtaactg gagtggccat tgcttttcaa gattacaagg aagtctatgt
     8101 ttctactaaa gacaaacgta gtggagaaaa aatcagggct gaggatttca aaccagcagg
     8161 aaatagtttt gccattccgg tgtcagatcc agtgtcagat caagatttag gagtgattta
     8221 catctccttg gatcctgctg ttttatacca tgccattgat aatactagag gtcatactcc
     8281 gatggcagta acagtgacct caccttttga tacggagatt tttcatattg gtgagacagt
     8341 tgataaggag agtgaaaatt ggctagttgg cttaacttct catggatatc aggttcaggt
     8401 ggcagttcct aaaaactttg ttttacaagg aacagtgact agctctgctt tgattgtggg
     8461 tttgagcctt ctctttattg tcattcttta tctgactttg aggcagactt ttgctaatta
     8521 ccaaaagcag gtagtggatt tagtagaatc cattcaagtc attgctcaag gcgaagaggg
     8581 gcgtcggatt gacatttccg agaaagatca ggaattactc ctaatcgcgg agacgaccaa
     8641 tgatatgttg gatcgattgg aaaagaatat ccatgatatt taccagttag agcttagtca
     8701 aaaagatgcc aatatgcgag ccttgcaggc gcaaatcaat cctcatttta tgtataatac
     8761 gctggagttc ttgcgcatgt atgcagttat gcagagtcaa gatgagttgg cagatatcat
     8821 ttatgaattc agtagtctct tgcgtaacaa tatttccgac gaaagagaga ccctcctcaa
     8881 acaggaatta gaattttgcc gtaaatacag ctatctctgc atggttcgct atcccaagtc
     8941 cattgcctat ggtttcaaga tagatccaga gttagagaat atgaagattc ccaagtttac
     9001 cttgcaaccg ctggtagaaa actatttcgc gcatggtgtt gaccacaggc ggacagataa
     9061 tgtgattagc atcaaggctc ttaaacagga tggttttgtg gaaattttgg tggtcgataa
     9121 tggtagagga atgtcggctg aaaagttggc aaatatccga gaaaaattaa gtcagagata
     9181 ttttgaacac caagccagct acagtgatca aaggcagtct atcgggattg tcaatgtaca
     9241 cgagcgtttt gtgctctatt ttggagaccg ctatgccatt acgatagagt ctgcagagca
     9301 agccggtgtt cagtatcgta ttacaattca agatgagtag aaagggagaa aatgtataaa
     9361 gtattattag tagatgatga gtacatggtg acagaaggtc tgaagcgttt gattcccttt
     9421 gataagtggg atatggaggt cgtcgcaaca gccggtcatg ccgatgaagc tctagaatat
     9481 gttcaggaaa atcctgtcga tgtcatcatt tccgatgtca atatgccaga caaaacaggg
     9541 cttgatatga ttcgggagat gaaagagatc ttaccagatg ctgcctatat cctgctctca
     9601 ggttatcagg agtttgatta tgtaaaaaga gcaatgaacc ttagtgtggt ggactatttg
     9661 gtcaagcctg ttgataaggt agagctggga aatctgctgg agaagattgc aggtcagctc
     9721 ggcgagagag ggaagaaaag tcagactctt agtcaagaat tagacgaggc tggatttgtt
     9781 agttatttag gggataagga gaattggtgg ataggtctat ccaaggaaaa acaaggttcc
     9841 ttcaccattc cctactatgt cttgggtcaa gactggcaga ttttcatttc tggccaaccc
     9901 ctagatggtt tagtcgttac accttttgaa gctccttatc aagaacactt tgaacgctgg
     9961 aagctgaatg ctgagaaaac cctcttttac ggttctgtaa atttgcagca gtctgagagt
    10021 ctctttgcct attacgaacc gatttatagg gttatcattc agggaaatct caatcaaatc
    10081 gtagaagagt taaatctctt ggagaaggta gttcttgaaa atacgccgcg tgttccgatt
    10141 actaaacagc tttttattca gtttgtcatg gatgttttcc atttatttga acatctcaaa
    10201 gctgatgacc tgacagacat cgtcaaaacc attcatgcta ttcaatcctt cgatgaattg
    10261 gttccttata tcaaggaaac tctgaccagc tttttcggtc aataccgtat gaatgaaaat
    10321 gtggccagtg tgctggaagt cattggtcgt gattaccaaa aagagctttc cctcaaggat
    10381 atcagtaagg ccctctttat caatcctgtc tatctagggc agttgattaa gcgtgaaacc
    10441 gattcgacct ttgcagagtt actaaacaaa caacgtatta aggctgccca acaacttttg
    10501 ctttcaacta gtgacagcat cgaagatatt tgttatgctg ttggttacag taaccttgga
    10561 tatttctata aagttttccg aaaattgtgc ggaaaatcgc caaaagccta ccgaaaacag
    10621 gtagaaacta tactataaga tttgtattcc tttacaaaag gtgctataat attatcagga
    10681 ggtcctatca tgaaaaagaa accaatttat ctatgggtct tgctaatctt gtctgccctt
    10741 atttcagttc cgtctctgtt tggaattgtg agtcccttgc ctagtaaaga agcccttcgt
    10801 gctgctcaga aacaagttgc aggggtcaat gctcagcaat tagaagacca gcttaattat
    10861 acctatagag tagcagaagc atctcattct atttttaatg ttgctttgat tgtgctatct
    10921 actattttag tggtcgtagc gattgtcttc cttgttcgta aaaatttgca atatgcaaac
    10981 tatacttacg ttggctatgt tttgttagct attattggtt cgatttatgg ctatgttggt
    11041 ttacaagacg ctgtgcagtt ggttcaagat gagagcatgc gtttgacagt gagtattggc
    11101 tcaaaagctg ttagcatttt ctatatcgtc atcaatgttc tcttcctagc ccttgtcttc
    11161 tataagatgt ggcgacaaca gaaagccttg gcagaagaag aggaaacaga agagcttgcc
    11221 taagtattga caaaaaagaa ctatcaagat acaatcttgg tagttgtttt ttgattatag
    11281 ataaaatcat ggaggtacat atgaagacaa tttctttagt ttatattagt ttgagtggca
    11341 acactgaaag ttttgtgacg cgcttgaaag actatctctt gtcccagtac aaagggattg
    11401 aggttcaaaa gattcatatc aaggatttgg tcaaggaagg caaaaatttc tatgaaatgg
    11461 accatcccta tgtcgctttt ttgccgacct atctcgaagg tgggaatggc gtggataacg
    11521 gagatgttga gattttgacg acaccggtgg gagattttat tgcctatggt aacaatgcta
    11581 gtaagtgttt tggtgtggtt gggtcaggaa atcgtaactt taataaccaa tactgcctaa
    11641 cagccaagca atacagtcaa cgctttggct tccctgtatt ggctgacttt gaaatgcgag
    11701 gcatgctgga agatatcaaa catgtcgcag ctattatcgc agatttgtat gagttggaaa
    11761 aggagaatta atactcaatg aaaatcaaag agcaaactag gaagctagtc gcaggttgct
    11821 caaagcacag ctttgaggtt gcagatagag ctgacgtggt ttgaagagat tctcgaatag
    11881 tataaagttc ttataagagg tggttgaagt tgttcaactg ttttttgagt ataaacagtc
    11941 tttaagaacg taaaaaagca taagttcagg tcttcaaaac cttgttctta tgctttttat
    12001 catagaaata tttgctgaat tttctcttga aatgaaacct tatcttcatc tcgcgcttgt
    12061 cccttaccct gcttttccga ttgcgagtgc gtagataaag aagatggcga agccaaagag
    12121 gaaaatcaat cccgcaatgg caaggtgttt gagccaagaa ggaagatttt tgttttcacg
    12181 cgttaccaag gcgtaattca aaagagcaaa gaaaggtgtt gtcaggaaag atccaatcat
    12241 ggcaaagcgg agcatggttg aaacctgacc agcgaagaac ttgataatga cgataccgat
    12301 gatagcagtg atggtcatcc agatgttcaa agatttacga ttgtcctctt tttgactgat
    12361 tagcagtcgg agagattcct gattaacgcg agaatagcca tcgataacag ttataactgt
    12421 tccaaagata cagaggaagg caataaaggt aatcaagtaa cgggaccatt cgccaagaac
    12481 agaggcatac atgcccacga attgagagat gtatttggct gaagcagctt caaccgcctg
    12541 ccctgtagga tattgaatca gtgctcccag tgccacaaag aagacggcta ggatagctgt
    12601 tccaatataa ccagtgttaa agtcaaacag agcgtcttct gtgttaaagt tgacggtctt
    12661 tctcttttca gctgaccaaa gtgaattgat ggctgaaatt tcaataggag ccggcatcca
    12721 tcctaggagg gagacgatga agggcagagc tgccatttgc caaggtgtct tctcgacaaa
    12781 atcagaactg tattctggat gcttgaccgc cgcaatgata actgccagaa cagtcgcaat
    12841 ggttaaggca gacataatcc atttgaccat gccgtctaaa agtttgtagc ctccaaagag
    12901 tagcatagcc caaatgattg caacgagaat gagggaccac tgagtaatgc taagtccaat
    12961 cattgggaag gcactggcga tgatagctga gcacagaatg gcaacaccag ccgtgttgac
    13021 catagccgaa aagacattga ggataaagaa aatccagaga tagagttttc ctttttcggc
    13081 ataaccttca accaaagtct ttccagtatc agctgtgtat tcagcaccaa aacggaaaaa
    13141 tggatattta aagacattgg ctaagatgac caagagaagt agagaccaac cgtaagaacc
    13201 gccagcttga gttgaggata caatgtggga acctccaaca gcggcagttg ccattaggat
    13261 tccaggtccc attgctttta gcttgcttgc ccaggttgat tgatttaagg aaatagcttg
    13321 cgacatgata aatactcctt tttgaatttt cagaataatc tgtatatgta atctatattc
    13381 tacaaaaaat tttggaaaaa tgcaagagta ttttgaaaaa agatagaaaa tttacaaaga
    13441 agatctgaaa taactgttat gatatagcgg attgaaacta gaatagtaca cctttgcttc
    13501 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
    13561 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
    13621 cttattatga ggtgcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
    13681 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
    13741 gagctggagg tagaaaatcc agtggaaggg gaaccaacca gcaagagttg ctagtgggac
    13801 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
    13861 gctgaataag cggttgccaa agttgaagag cataccgatg gctgcccaga taagtgtgca
    13921 gtagagcaag accagggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
    13981 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatggagag
    14041 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
    14101 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
    14161 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
    14221 atgatttctg attgggaaat ttggataaaa ttgcttggca agagtttaag aacctgatag
    14281 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
    14341 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gatttttcct
    14401 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg gactttttcg
    14461 gtttcttgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtagt
    14521 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
    14581 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
    14641 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
    14701 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
    14761 gcaagggact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
    14821 ttctgaaata tggtataata gcactaatta atttctagga aaatagatac agaaaggggc
    14881 tgaaagatgt ctcatattat tgaattgcca gagatgctgg caaaccaaat cgcagctgga
    14941 gaggtcattg aacgtcctgc cagtgtggtc aaagagttgg tagaaaatgc cattgacgcg
    15001 ggctctagtc agattatcat tgagattgag gaagctggtc tcaagaaaat ccaaatcaca
    15061 gataacggtc atggaattgc ccacgatgag gtggagttgg ccctgcgtcg ccatgcgacc
    15121 agtaagataa aaaatcaagc agatctcttt cggattcgga cgcttggttt tcgtggtgaa
    15181 gccctgcctt ctattgcgtc tgttagtgtc ttgactctgt taacggcggt ggatggtgct
    15241 agtcatggaa ccaagttagt cgcgcgtggg ggtgaagttg aggaagtcat cccagcgact
    15301 agtcctgtgg gaaccaaggt ttgtgtggag gatctctttt tcaacacgcc tgcccgtctc
    15361 aagtatatga agagccagca agcggagttg tctcatatca ttgatattgt caaccgtctg
    15421 ggcttggccc atcctgagat ttcttttagc ttgattagtg atggcaagga aatgacgcgg
    15481 acagcaggga ctggtcaact gcgccaagca atcgcaggga tttacggttt ggtcagtgcc
    15541 aagaagatga ttgaaattga gaactctgac ctagatttcg aaatttcagg ttttgtgtcc
    15601 ttgcctgagt tgactcgggc taaccgcaat tatatcagtc tcttcatcaa tggccgttat
    15661 atcaagaact tcctgctcaa tcgtgctatt ttggatggtt ttggaagcaa gcttatggtt
    15721 ggacgttttc cactggctgt cattcacatc catatcgacc cttatctagc ggatgtcaat
    15781 gtacatccaa ccaagcaaga ggtgcggatt tccaaggaaa aagaactgat ggcgctggtc
    15841 tcagaagcta ttgcaaatag tctcaaggaa caaaccttga ttccagatgc cttggaaaat
    15901 cttgccaaat cgaccgtgcg caatcgtgag aaggtggagc aaactattct cccactcaaa
    15961 gaaaatacgt tctactatga gaaaactgag ccgtcaagac ctagtcaaac tgaagtagct
    16021 gattatcagg tagaattgac tgatgaaggg caggatttga ccctgtttgc caaggaaacc
    16081 ttggatcgat tgaccaagcc agcaaaactg cattttgcag agagaaagcc tgctaactac
    16141 gaccagctag accatccaga gttagatctt gctagcatcg ataaggctta tgacaaactg
    16201 gagcgagaag aagcatccag cttcccagag ttggagtttt tcggacaaat gcacgggact
    16261 tatctctttg cccaagggcg agatggactt tacatcatag atcagcacgc tgctcaggaa
    16321 cgggtcaagt acgaggagta ccgtgaaagc attggcaatg ttgaccagag ccagcagcaa
    16381 ctcctagtgc cctatatctt tgaatttcct gcggatgatg ccctgcgtct caaggaaaga
    16441 atgcctctct tagaggaagt gggcgtcttt ctagcagagt acggagaaaa tcaatttatt
    16501 ctacgtgaac atcctatttg gatggcagaa gaagagattg aatcaggcat ctatgagatg
    16561 tgcgacatgc tccttttgac caaggaagtt tctatcaaga aataccgagc agagctggct
    16621 atcatgatgt cttgcaagcg atctatcaag gccaatcatc gtattgatga tcattcagct
    16681 agacaactcc tctatcagct ttctcaatgt gacaatccct ataactgtcc tcacggacgt
    16741 cctgttttgg tgcattttac caagtcggat atggaaaaga tgttccgacg tattcaggaa
    16801 aatcacacca gtctccgtga gttggggaaa tattaaaagt ataaaaaagt ctgggaaaaa
    16861 ttttcaaaat cagaaaaacg cataaaatca ggtgttcaaa aaccttgatt ttatgcgttt
    16921 tatcatagaa atatttactt catgttttcc taattctttt cgaaactctt tttaaaccac
    16981 gtcagtttta tcagtaatct caaaacagtg ttttgagcta attttgccag ttttgtctgt
    17041 aacatcgaag ttgtgtttta ccactctgcg actggtttcc tagtttgctc tatgattttc
    17101 acagagtatt aaattgcgat tttgccaagt ttctttattc gtctaaaagt agagtctgtt
    17161 ctatgcgtct aatgtacgaa ttaggttgac catttcaata gctccttgtg cacactcaga
    17221 acccttattt cctgctttgg taccagctcg ttctatggct tgttcaattg tatctgtcgt
    17281 tagcacacca aacataacag gaatttcgct atttaaactg atttgggcga ttcccttaga
    17341 tacctcgcta catacataat cataatgact tgtattccct ctaatgacag ctcccaagca
    17401 gataattgca tcatattttt tactttttgc catttttgat gcaatcagtg gtatttcaaa
    17461 agctcctgga acccaggcta cctctatatc tttctcgttt acattctctc ttttgagatt
    17521 atctagtgct ccagataata attttgaagt tataaattca ttaaatctcg ctacaacaat
    17581 acctatttta atattgtttg ctactaaatt accttcataa gtgttcattt atttttcctc
    17641 catatttaaa atgtgaccca ttcgattttt ctttgtttct aaataaaaac tatcgtaagg
    17701 attggcttct atttcgattg atattctact ggaaatggta attccatatt tttctaactg
    17761 ttcaaccttg tcaggattat ttgtcagtaa atgaagtgac tgaagtccca gatctttaag
    17821 catttgtgct ccaatatgat attctcttaa atcaccttca aagcctaatg caagattggc
    17881 atcaagcgta tccatgcctt gatcttgtaa atgataggct tttaatttat tgataagtcc
    17941 aattcctcgt ccctcctgtc gcaagtaaag taagacaccc gaaccattct caacaatcat
    18001 tttcatagct ttatcgaatt gctgtccaca atcgcaacgt aaagagccta aaacatctcc
    18061 tgttaaacat tcggagtgga cccgacataa tacattggct tcatcctcta tgtttcccat
    18121 aataagagca agatgatgtt ccccatttag tttatctata tagctaattg ctttgaaatt
    18181 accgtatcta gtaggcatat tgacagttga aactcgttct accagctgat catatacttt
    18241 tctatattct tgtaattctt tgatggtaat tagtggaatg ttgtgtttct tcgagaactg
    18301 aattaaatca tctgttctca tcattttgcc atcatgattc attatttcac aacataggcc
    18361 acactctttt agtccagcta attttaataa atcaacagtt gcttctgtgt gtccatttct
    18421 ttctagaaca ccaccttttt ttgcaattaa aggaaacatg tgtcctggcc tgcgaaaatc
    18481 agagggtgtt atatcttcag ctacacacat acgtgcggtc agtcctcttt cctcggcaga
    18541 aatacctgtg gtcgtttctt tataatcaat tgaaactgta aaagcagtct tatgattatc
    18601 tgtattgttt tcaaccatag gtgaaagcat taattgatta gctaaacttt cgctcatagg
    18661 catacaaatt aatcctttgg cataagtagc cataaaatta acattttctg ttgtagctgc
    18721 ttgtgcagaa caaattaagt ctccttcatt ttctctatcc ttgtcgtcta taacaagaac
    18781 aagtcgtccc ttctgcaatg cttctaatgc ttcttgtatt tttcgatatt ccattgactg
    18841 attatccttt ctgctaaaat ccattttgat ataatagttc cttagatatt tctgattttg
    18901 gagagttatc catcagtttt tgcacatatt tacctaagat atcattttca agatttactg
    18961 tactcccgac ttgtttactc ttaagaatgg tttgttccaa ggtatgaggg ataacagata
    19021 ctgaaaagtt tactttggag actttagcga cagtcagact aatgccgtca attgtaatag
    19081 atcctttttc aactattaaa tctaaaattt ctttttgtgt gttgatttga taccatacag
    19141 cattatcatc tttttttatt gacgagattt ttcctgtacc atcaatgtgt cctgtaacga
    19201 cgtgaccccc aagtcgaccg ttgacagata aggctctttc tagattcacc tcacttccat
    19261 gttttaatag agtaagagct gttcgactcc atgtttcatt cattacatca actgtaaagg
    19321 attgatgatt gaaatgagta actgtaagac agataccatt tactgctata ctatcgccta
    19381 aatggatatc cgttaatatt tttgaggctt taattgatag tttacaatta cgagagtctt
    19441 tctgtattct ttcaactttt ccgatttctt caattattcc tgtgaacatg gataaatcac
    19501 ttcactttct atgagatagt catttcctat ttgagaaaaa gcataaggtt tcaatctaat
    19561 agcgtcattt ggcaaagaaa tgccttcacc tccgacagga aacttggcac tgcctccaaa
    19621 aatttttggt gcaatatata ttttcagctc atcaacaatt tgttgttcca aagcactcca
    19681 attcattaga ctgccccctt ctagaactag gctatcaatc tgcatgtttc ctagatgttg
    19741 cattaaactc gataagtcta tatgattgcc ttttttcttt atggaaagta tttcacagcc
    19801 atgattttga tatagcttca ttttattttt gtcttcagag gaagtggcaa tgtaagtttt
    19861 aatatcattt gctgttttta cgattttaga ggtaagagga gttcgtaaat gtgtatcgca
    19921 tatgatacga ataggatttt tcccttcctc caatctacat gtcagcaaag gatcgtcttg
    19981 aataacagta ttgactccca ccataattgc actaacatgg tgtcgtaact gatgcacatg
    20041 ctttcttgct tcttcttcag taatccattt ggattgattt gttttagtgg ctatttttcc
    20101 atccattgac attgcatatt tcataaaaac atagggtaca tgctgggtaa tatactttct
    20161 aaaacttttt attaagttaa gacactcatt ttctaaaatt ccaacagtaa cttgaagatt
    20221 attttcctca agtatcttta ctccttttcc agatacaata ggattacagt ctaggcttcc
    20281 aatgactact cttgtaatac cactatcgat tatagcatct atacaaggag gtgttttccc
    20341 gaagtgacaa cagggttcaa gtgttacata aagcgtcgct ccgacagggg attctctaca
    20401 gtttttaaga gcatttctct cagcatgtga gccaccaaaa aactcatgat aaccttgtcc
    20461 gatgatgtga ttatctttta caataactgc gccgaccata ggattgggat tgacgtaacc
    20521 agcccctttt tgtgccagtt ttattgctaa tttcatatat tttgaatcgc tcatctcact
    20581 acctccaaaa aaatatacct tgaataggag actactcaag gcatacaaaa gaaaacttat
    20641 gcgattaaca aaaatgctct gaaatgacaa gtaatcattt cagagcacgc aaaaagcaca
    20701 aatatacttt tatcttcttt catccagact atactgtcgg ctttggaatt tcaccaaatc
    20761 atgcctttcg gctcgtgggc tataccaccg gtagggaatt gcaccctgcc ctgaagatag
    20821 ttattcaatt acagatgatt atagtactta attttgaata tgtcaacaga taaataccga
    20881 ttgtttttga tatactgtat ttgtgataat cgattctcgc tcctcggata aagaaaatat
    20941 gatatactag ataaacgaaa taagagagaa ggaacactat gtacgcatat ttaaaaggaa
    21001 tcattaccaa aattactgcc aaatacattg ttcttgaaac caatggtatt ggttatatcc
    21061 tgcatgtggc caatccttat gcctattcag gtcaggttaa tcaggaggat cagatttatg
    21121 tgcatcaggt tgtgcgtgag gacgcccatt tgctttatgg atttcgctca gaggatgaga
    21181 aaaagctctt tcttagtctg atttcggtct ctgggattgg tcctgtatca gctcttgcta
    21241 ttatcgctgc tgatgacaat gctggcttgg ttcaagccat tgaaaccaag aacatcacct
    21301 acttgaccaa gttccctaaa attggcaaga aaacagccca gcagatggtg ctggacttgg
    21361 aaggcaaggt agtagttgca ggagatgacc ttcctgccaa ggtcgcagtg caagcaagtg
    21421 ctgaaaacca agaattggaa gaagctatgg aagccatgtt ggctctgggc tacaaggcaa
    21481 cagagctcaa gaaaatcaag aaattctttg aaggaacgac agatacagct gagaactata
    21541 tcaagtcggc ccttaaaatg ttggtcaaat aggagcagag aatgacaaaa cgttgttcgt
    21601 gggtcaagat gaccaacccg ctctacatcg cctatcatga tgaggagtgg ggtcagcccc
    21661 tccatgatga ccaagcattg tttgagttgt tgtgtatgga aacctatcag gcaggcctgt
    21721 cttgggaaac ggtactcaac aaacgccaag ctttccgaga agcctttcat agctatcaaa
    21781 ttcactcagt cgcagagatg actgacactg aattggaagc catgctggag aatccagcta
    21841 tcattcgaaa tagagccaag atttttgcta cacgcgctaa cgcccaagcc tttctacagt
    21901 tacaggcaga gtacggctct tttgatgcct atctttggtc ttttgttgag gggaaaactg
    21961 tcgttaacga tgttcctgat tatcgccaag ccccagctaa aacaccctta tctgagaaat
    22021 tagccaaaga tctcaaaaaa cgaggcttca agttcacagg cccagtcgcc gtattgtctt
    22081 ttctacaggc tgcagggcta gttgatgacc acgagaatga ttgtgagtgg agaggtctta
    22141 aatgatgtct aacaaaaata agggaattct gatttttgcg attctctata cagtcctctt
    22201 tgtgtttgat ggcgttaaat tgctggcttc tttaatgcca tctgccattg caaattatct
    22261 tgtttatgta gttttagctc tatatggctc cttcttattc aaggatagat tgatccaaca
    22321 atggaagggg attagaaaga ctaaaagaaa attcttcttt ggcgtcttaa caggatggct
    22381 ctttctcatt ctgatgactg ttgtctttga atttgtatca gagatgttga agcagtttgt
    22441 gggactagat ggacaaggtc taaatcagtc taatattcaa agtacctttc aagaacaacc
    22501 actactgata gctgtttttg cttgtgtcat tggacctctg gtagaagaat tatttttccg
    22561 tcaggtctta ttgcattact tgcaggaacg gttgtcaggt ttactaagca ttattctggt
    22621 aggacttgtt tttgctctga ctcatatgca cagtttggct ctatcagagt ggattggtgc
    22681 agttggttac ttaggtggag gccttgcctt ttctattatt tatgtgaaag aaaaagagaa
    22741 tatctactat cccctacttg ttcacatgtt aagcaacagc ctctccttaa tcattttagc
    22801 tatcagtata gtaaaatgaa atgagaacag gacaaatcga tttctaacaa tgttttagaa
    22861 gtagaggtgt actattctag tttcaatata ctgtaatatg tgatgaaaat gccagtaatg
    22921 ataccgagaa aaaagctgag aaacttttcc cagctttatt tgttatagtc aaagagaatg
    22981 acttgttcct gtgcatctac atgagcatgg accccaaagg gtacaattgc tcttggagtt
    23041 gcgtggccga cattcagatt atagacaatc gggatattgc tgtcaatgat atccaatagt
    23101 gcctctttat agtcgtcatg gaaagtttca tccataggtt ttccgaccaa gagtccattg
    23161 atgaccgcga atatgccagt gtcctttaaa gttagcaaca tctttttgaa gtcttctggc
    23221 ttaggctttt cttcgcttgt ttcgagcaag aggattttcc cttcccagtc tgacaagtca
    23281 gggaaaagtt tgtatttttg gcagagctcc gtgctatctg cgtatcgaga gttgtcaaag
    23341 atatcgtaga gggattcgag gcaaccaccg aggattttcc cctcgaactg ggcacttcct
    23401 tgcaacaagt caaaacctgt atttgtatga ctgacacgag gtgttcccag ggccgtggga
    23461 ctaaaatcag ttcgttcctc ataccaaacg tcactagggc ggatttctga aattcttccc
    23521 gtctcaatca attctttaaa gtagtgaagg ctataggcta gcatttcttt gtctaattca
    23581 caaatgtctg ctaaaaagga ttgaccataa aaagtcttga ttcctaattt atgcaacatg
    23641 aggtggttca tggttgtatc cgagaagcca agaaaaattt tttgtttgat aaccttttgg
    23701 agttggtcat tttcaaaaag ataaggtagc aagcgatagg tatcgtctcc accgatggca
    23761 cataggatca tgtcgatgct atcatcagaa aaggcatgaa tcaaatcctc tgcacgagct
    23821 tcaggatggt ccttgataaa gtctaatcct tttaacgaat ggggcaaaaa gatgggattg
    23881 agtctcagat ccttgagacg ttggataccc aagtccactt cgtgtttgac aaaatcctct
    23941 ccgataatgc cactagataa actaacaata ccaatagtag aaaccatatc tcatcctcct
    24001 agaaatagat tgagcctatt ttatcacaaa atataagaga aagctatgtg ggatttcaga
    24061 agaatacttt taatactctt cgaaaatctc ttcaaaccac gtcagtttta tttgcaacct
    24121 caaagctgtg ctttgagcaa cctgcagcta gcttcctagt ttgctctttg attttcattg
    24181 agtataactc aaaaaagtaa gtgaaaaagc aaccgcacct gcagttgctt ttatcgtttt
    24241 cttattcttg atagcgtgtt ggtcctgcac ttgcactacg gatattcaag cgtttcttga
    24301 gatagaagcg aagggctagg agggctgctc caataatagc tagtggcaat ggatccagta
    24361 ctgggttaag gctagctggt aggaagcttg ttgcaaagaa gacaagcaac caaaggaaca
    24421 tagaagctag gataactagt acagatttcc agaaaggtgg acgttgactg cgatccatat
    24481 ttggtccata gtattggtaa acaaagtagt acatcaagta gaaggcaaat ccaccaacca
    24541 gtccaactaa tagaagagta atcaatccat agccgaaagc ttgatctgcc gcaaagaagg
    24601 ttgtgagggc gctgacaagg gcaaagaggc tagtgatgaa aagagctgag tccataatca
    24661 tcagttttgg atcatcattt tcttttggat gctctttttc gtactgctct ttgacagtga
    24721 agctatgagc ccaatgagtt ggtgcgccgt atagggaacg ggcagttgta cctttagatt
    24781 gctcctcaag gatttgggga atgacttcct caaaaatagt ctggatttca gcgtctgttt
    24841 tcccatcttt gatgaattgt tgggtagcaa tgtggacaaa ctcttggttt ttcttagtta
    24901 atttttgtag atcaatttga gacataggaa ctcctcttag aaccattttt tatggatgag
    24961 atagagagtg agcgagacac tcatagcaaa ggcgataaag acgattaacc agaaggcatt
    25021 tggctctccg tttaggggga tttcattatc cttaaagttc atcccgtagg cagaaaagac
    25081 catggttggg atggacatga cgatggtcac aagggccaag gttttcatga tgttgttctg
    25141 gttgttagaa atgatagagg caaaggtctc tgtcatagaa tgcaagacgt ttccataaat
    25201 atctgccatc tcgatggcct gttgggtttc aatcagggtg tcttcaagca ggtcttcgtc
    25261 ctcaaggtat ttcttgatat tgctggttga actggtcaat ttcttaatca cgcgctcatt
    25321 tgttttgagg gaggccttga aatagacgat agttttttcc aattccatga gctcaatcaa
    25381 ttcttcatta cgagttgatt gatgcagttg actttcgatt tgttcactct tgcggtcgat
    25441 tgaacgaagg gctgttaggt aaagctctgc attgcgataa agaatttgaa agataaaacg
    25501 tgaacgcatg aaggtataga aattacgcaa tcgacggttg ataaagacat caaggacagg
    25561 tagtggttcc aaacacgtag tgataatggt ttcctcagtg atgataatac caagcgggat
    25621 ggttacgtag taggtgcggt tatttctttc ctccgtgacc ggcacgtcta cgataatcag
    25681 ggtatactcg tcttcaatgg taatacgaga catttcttcc gcatcgagcg gtgctcgaag
    25741 gtcggcaata tcaatatcga aggtgttggc gatttcgagt gattcatttt gagtcggatt
    25801 gacgagattg atccaagtac ccggttcaag cgtatcgatc tctttaaatt cagttgttgt
    25861 agagagaaaa acttgtttca tatcccttat cctttctcat ttttcagatt ttttcacact
    25921 gtactattat actacaaaat cggccttttg ggtaatagaa tctcactttt tttggtataa
    25981 tggtaagcaa taatggacta gaaagaacaa agatgcaaga taaaattgtc attcatgggg
    26041 cgcgtgccca taatttaaaa aatattgatg tggagattcc gcgagacaag ttggttgtcg
    26101 tgactggctt gtcaggttca gggaagtcca gtctggcttt tgatactctc tatgcggagg
    26161 gacaacgtcg ctatgtagag agtttgtctg cctacgctcg tcagttcttg ggaaatatgg
    26221 aaaaaccaga tgtagatgcc attgatggtc tcagcccagc tatttccatc gaccagaaaa
    26281 cgactagtaa aaatcctcgc tcgacggtgg gaacgacgac tgaaatcaat gactatctgc
    26341 gtctcctcta cgcacgtgtg gggacgcctt actgtatcaa cggacatgga gctatcaatg
    26401 cttcttctgt ggagcaaatc gttgataagg ttttggagtt acctgaacgc cagcgcttgc
    26461 agatcttggc tcctgtcatc cgcaagaaaa aaggccaaca taagagtgtt atcgagaagg
    26521 ttcagaaaga cgggtatgtt cgtgttcgtg tggatgggga agtctatgat gtgaccgaag
    26581 tgccagagtt gtctaagagc aagcaacaca atatcgatgt cgtggttgac cgtattgtta
    26641 tcaaggaggg cattcgtagc cgtctctttg attccattga agctgccctt cgtatcgcag
    26701 aaggttatgt gattatcgac accatggacg actctgagtt gttgttctct gagcattatg
    26761 cctgtccagt ttgtggattt actgtcccag agttagaacc tcgtctcttc tctttcaatg
    26821 ctccctttgg ctcttgtagt gagtgtgacg gcttggggat taagctggag gtggatactg
    26881 atttggtagt gccagatgcc agcaaaacct tacatgaggg agcgctggca ccttggaatc
    26941 ctatctcatc caactactat ccaaacatgt tagagcaggc catgaaagtc tttggagtgg
    27001 ctatggataa gccttttgag gacctgtcag aagaagataa gaacttgatt ctctacggct
    27061 cagatggtaa ggaattccat ttccattatg aaaatgaatt tggtggtgtg cgcgatatcg
    27121 acattccgtt tgagggagtt atcaataata tcaaacgtcg ttaccatgaa accaatagcg
    27181 attacactcg cactcagatg cgtctctata tgaatgagct gacctgcgga acctgtcaag
    27241 gctatcgtct caatgaccag gccttgtctg tccgtgtggg cggccagcaa gggccacata
    27301 ttggagaaat ctcagacctg tctatcgctg accacttgga cttggtgagc cagttaactt
    27361 tgtctgaaaa tgaagccatc attgctcgtc ccattctcaa ggaaatcaag gatcgtttga
    27421 ccttccttaa taatgtgggt cttaactatc taaccctgtc acgttcagca ggaacccttt
    27481 caggtgggga aagtcagcgc attcgtttgg caacccagat tggttccaac ctatcaggtg
    27541 tcctctatat cctagacgag ccgtcaatcg gtcttcacca gagggacaat gaccgcctga
    27601 ttgccagtct gaaaaagatg cgtgacttgg gcaatactct tatcgtggtg gaacacgacg
    27661 aagataccat gcgtgaagct gattatctga ttgacgttgg tcctggtgcc ggtgtttttg
    27721 gtggtgagat tgttgcagca ggtacaccta agcaagtggc tcgcaacagc aagtctatca
    27781 caggtcagta cttgtcaggc aaacgtgtca tcccagtacc agaagagcgc cgtgtcggaa
    27841 atggtcgttt tattgaagtg acaggagcgc gtgagaacaa cttgcaaaat gtcacggctc
    27901 gctttccact aggaaaattt atcgcagtga caggtgtgtc gggttcaggg aaatcgactc
    27961 taatcaacag cattctcaaa aaagccattg cccagaagct caaccgtaat tcagacaaac
    28021 ctggtaagtt taagactatt acagggattg agcatgtcga ccgtttgatt gatattgacc
    28081 agagccctat cggacggacg ccgaggtcta acccagctac ctatacagga gtttttgacg
    28141 atatacgtga cctttttgct cagacaaatg aagccaagat tcgaggctac aagaaggggc
    28201 gcttcagttt caacgtcaag ggaggtcgct gtgaagcttg ctcaggtgac gggattatca
    28261 agattgagat gcacttcttg ccagatgttt atgtggcttg tgaagtttgc cacggaaccc
    28321 gctataacag tgaaacccta gaagttcact acaaggaaaa gaatatttcg caggtcttgg
    28381 atatgacggt caacgatgcg gtagaatttt tccaacacat tccgaaaatt caacgcaaac
    28441 tccagaccat caaggatgta ggtctaggct atgtgacctt gggacagcca gctaccaccc
    28501 tttctggggg agaagcccaa cgtatgaagt tagctagcga actccacaaa cgctcgacag
    28561 gaaaatcttt ctacattctg gatgagccga cgacagggct tcatacagag gacattgctc
    28621 gcctgctcaa ggttttagct cgctttgtag acgacggcaa tacagtcctc gtcatcgagc
    28681 acaatctgga tgttatcaag acggcagacc atatcattga cttgggacct gagggcggtg
    28741 tcggtggtgg aaccatcatc gtaacaggaa ctccagaaga agtagctgcc aacgaagcca
    28801 gctatacagg acactatttg aaaggaaagt tacatcatga ataaacgcgt acaagcattt
    28861 ctagctaaaa tgcaagaaaa agaactagat ggtatcatca tcaacaatct taaaaacgtc
    28921 tattatttga ctggtttttg gggctcaaac ggaacagtct ttatcagccg tgaccgtcag
    28981 gtcttagtga cagactctcg ctatatcatc gcagctaagc aagaaaccag tggttttgag
    29041 attgtggctg atcgtgatga attggctgtc attgcaggaa ttgttaagga catgaacttg
    29101 actcgtatcg gttttgaaga tgagatttca gtgtcttatt accaccgtat gcaggcagct
    29161 tttgcaggtt tgaacttgct tccacaaact cagtttgtgg aaggtcttcg tatgattaag
    29221 gatgaggcag agattgcagc gattcgcaag gcttgttcta tctcagacca agctttccgc
    29281 gatgcgcttg actttatcaa accaggaaaa actgaaattg agattgccaa cttccttgat
    29341 ttccgcatgc gtgagttggg agcatctggc ttatcttttg atacgatcct agctagcggt
    29401 atcaattctt ctaaacccca tgcccatcca atgcacaaac cagtggagtt gggagaagcc
    29461 attaccatgg acttcggctg tctctatgac cactatgtca gtgatatgac ccggactatc
    29521 tatctagggc atgttagcga tgagcaggca gagatttaca atacggttct aaaagctaac
    29581 caagccttga ttgaccaagc taaggcaggc ttaggtttcc gtgactttga caaaatccct
    29641 cgtgatatta tcattgaggc aggttatggt gactacttta ctcacggcat tggccacggt
    29701 attggtctgg atatccatga ggaaccctac tttagtcaga cttctacaga aactattaag
    29761 acaggtatgg ccttgaccga tgaaccaggt atctatatcg aaggcaaata tggcgttcgt
    29821 atcgaggatg atatcctgat tacagagaca ggttgtgaat tattgaccct agctccaaaa
    29881 gagttgatag tcatttagtt gtttgtcaag aaaaaagtac gaaaatgacg aaaaaagtca
    29941 aaaaaaatta aaaataggtc gcaagtcgga tgttttttat ggtataatag actaaactga
    30001 tagtaacatg tagcgaaagg ggtaggtaca tgattaaaat ttatacagtc tcaagttgta
    30061 ctagctgtaa aaaagcaaaa acctggctca atgcccacca gttaagttat aaagaacaaa
    30121 accttggtaa agaaggaatt acgagagaag aattactgga tattctaacc aaaacagata
    30181 acggaatagc cagcatcgtt tcgtctaaaa atcgctatgc caaagccctt ggagtggata
    30241 ttgaagattt gagtgtcaat gaagttctca atctgattat ggaaacaccg agaattttaa
    30301 agagcccaat ccttgtagat gaaaaacgcc tgcaagttgg ctacaaggaa gacgatattc
    30361 gtgccttcct accacgctct gtccgtaatg tagaaaatgc agaagcacgt ttgcgtgcag
    30421 ctctataaac atcaaggctg ggagcacttc ccagtcttat tctattttaa tttcaaaaag
    30481 aaagaagaaa gaaatgaaaa aaatagttct tgttagtcta gctttccttt ttgtcctggt
    30541 tggttgcgga cagaaaaaag aaactggacc agctacaaaa acagaaaaag atacgcttca
    30601 gtcggcattg ccagttattg aaaatgctga gaagaataca gttgtaacta agactttggt
    30661 cttgcccaag tcagatgatg gtagccagca gacacaaaca attacttaca aagacaagac
    30721 ttttttgagt ctagctatcc aacaaaaacg tccagtctct gatgagttga agacttatat
    30781 tgaccaacat ggagtggagg aaactcaaaa agctcttctt gaagcggagg agaaggataa
    30841 gtctatcatt gaagctcgta aattggcagg tttcaaactt gaaacaaaac tattgagcgc
    30901 aacggaactt caaacaacga ctagttttga ttttcaagtt ctggatgtca agaaggcttc
    30961 ccagttggaa catctgaaga atattggttt ggaaaatctt ttgaaaaatg aaccaagcaa
    31021 atatatttca gatagattgg caaatggcgc gacagaacaa tagaaaatcc aaataaatag
    31081 actgcctgaa ttgtagaagg taaggaatta tgctataatg gtactattct aaggaaagag
    31141 ggtgttagaa tgggatttac tgaagaaaca gtacgtttta aattggacga ttccaataaa
    31201 aaagaaatta gcgaaacttt gacagatgtt tatgcttcgt tgaacgataa gggttacaac
    31261 ccaatcaacc aaatcgtagg ttacgtattg agtggagacc ctgcctacgt tcctcgttat
    31321 aataatgcac gaaatcaaat ccgtaagtat gagcgtgatg aaatcgttga ggaattggtt
    31381 cgctactacc tcaaaggaca aggagtcgat ctataaccta tgagaattat gggattggac
    31441 gtcggttcaa aaacggtagg ggtggcgatt agcgatccgc ttggttttac agctcaaggg
    31501 cttgaaatca tccagataaa tgaagaacaa ggccaatttg gttttgaccg cgttaaggaa
    31561 ttggttgata cttacaaggt ggaacgattt gtagtgggct tgcctaaaaa catgaacaat
    31621 acaagtggac cgcgcgtaga agctagtcaa gcctacggag caaagctaga agagtttttt
    31681 ggtttaccag tagactatca ggatgaacgc ttgacaacag tggctgctga gcgcatgttg
    31741 attgaacaag cagatatcag tcgcaataag cgcaagaaag tcattgataa gttagcagct
    31801 cagctgattt tacaaaatta tttagataga aaattttaat ataaaggaga ggctatgtca
    31861 cacgatcata accacgacca cgaagaacgt gaactaatca cactagtaga tgagcaagga
    31921 aatgaaacct tgtttgaaat ccttttgaca attgatggaa aagaagaatt tggtaaaaac
    31981 tatgttcttc tagtaccagt taacgcagaa gaagacgaag acggacaagt tgaaatccaa
    32041 gcttactcat tcatcgaaaa cgaagatgga acagaaggcg aattgcaacc aatcccagaa
    32101 gactcagaag acgaatggaa catgattgaa gaagtcttca acagctttat ggaggagtga
    32161 tacagtctgg gagactgtat cagcccaact cccagaaatg gggaagagtt ggaacgtcca
    32221 gtgaacattt ttaccccaac tcttagaaat tgagaagagt tggaacatct agtggatgtt
    32281 tttagcccat attcacattc atagtagcta gttattagct aaccaggtaa gaggtcggga
    32341 cgaaaatcct ggccttgttt ttattagtaa ccatacttta atgcgataat tgattggact
    32401 tttgtcaagg agatgtgtat gtttgaagta gaagaatggc tccatagtcg gattggtttg
    32461 aattttcgat caggtttggg ccgaatgcag caagcggtgg atttgttagg aaatcctgag
    32521 cagtcttacc ctattatcca cgtaacaggg actaatggga aaggatctac cattgctttt
    32581 atgagggaat tatttatggg gcatggcaaa aaagttgcga cctttacctc ccctcatatc
    32641 gtctctatca atgaccgaat ctgcattaat gggcaaccta tagcagacgc agactttatc
    32701 cgtttgactg atcaggtcaa ggagatggag aaaacgcttc tgcaaactcc tgcccagttg
    32761 tccttttttg aattgctgac cttagttgct tttctttatt ttagggagca agaggtggat
    32821 ttggttttat tagaagtggg aattggtggc ttacttgaca cgaccaatgt ggtaactgga
    32881 gagcttgctg tcatcacctc cattgggctt gaccatcaag aaaccttggg tgatagtcta
    32941 gaagcaattg cagagcagaa agctggtatt ttcaaggctg gtaaaaaggc agtgattgcg
    33001 aaattgcctc cagaagctag acttgtctgt cagaaaaaag ctgaatcttt agctgttgac
    33061 ctttatcagg caggtcaaga tttttcagtg ctgaatggtg atttttcaag ctctttacta
    33121 aatctttcac agctgaacat aggcttagaa ggagcctatc agcaggagaa tgcggccttg
    33181 gcgttgcaaa cttttcttct ttttatggga gaaagaaagg aagctattga tgaacaggct
    33241 gtaagaaagg ccttggaaca gacccattgg gctggtcgct tggagcgtat tcgcccacag
    33301 atttacttgg atggtgctca taacctccct gccttgactc gcttggttga gtttatcaaa
    33361 gaaaaagagc aggaaggcta tcgacctcaa atcctctttg gatccttgaa acgtaaggat
    33421 tatcaaggga tgttgggtta tctgactgaa aatttacctc aagtggaact caaaatgacc
    33481 ggctttgact atcaagggtc tttggacgag acagatgtaa caggttacca tgtaattccc
    33541 tcttaccgag aatttatcag cagtttcgaa gaaagggcag acgctcaaga cttgctgttc
    33601 gttacagggt ctctctattt tatctcagaa gtacggggct acctgctgga ccgtgagcag
    33661 ataaattgac ccccttgttt gaacttgtta tactagggga attgctggtt agagaaaatt
    33721 tctctaaatt ggtagcagaa aggaaattca tcatgaaatt aaaaagattc acactttctc
    33781 ttgcttctct agcaagtttt agtctcttag tagcttgttc acaaagagct caacaggttc
    33841 aacagcctgt tgctcagcag caggtccaac agcctgctca acagaatacc aatactgcaa
    33901 atgcaggagg taaccaaaat caagcggctc cagtacaaaa ccaacctgtt gctcaaccga
    33961 ccgatattga tgggacttat actggtcagg atgacggaga ccgtatcact ttagtggtaa
    34021 ctggaacgac tggtacatgg actgagctcg aatctgacgg ggatcagaaa gtcaaacagg
    34081 ttacatttga ttcagcaaat caacgcatga ttattggcga tgatgtcaaa atttacactg
    34141 taaacggtaa tcaaatcgtc gtagatgata tggatagaga cccatcggac caaatcgttt
    34201 taactaaata agactatgca agtagaaagg gctggatttt tcagcctttt tacttttacc
    34261 tagaaaataa tcataaatac ttgccttcta ccgaatacct gcgttatact agtatcaatt
    34321 acttgttttt agcattcaaa ctatcaagga ggggatatga aatataggaa atttcaatta
    34381 ttgatgtcca agtatggctt tagtctttcg attatgctac ttgaactttg tcttgttttt
    34441 ggtctctttc tttatttagg acgcatggct cccattttat ggattactgt cctcattcta
    34501 ctgagtatca tcacaatcat ttcgatagtc aaccgtaata cgactcctga gaataaggta
    34561 acctggttgt tagtagcctt tgtgccagta tttggtccct tgctctatct gatgtttggt
    34621 gaaaggcgat tgtccaaaaa agaaatcaaa caactgaaga agctaggctc tatgcatttc
    34681 caagaagcaa atagccagct actaaaagag aaattaaaag aaagtgacaa ggcagcttat
    34741 ggagtcatca agtccttatt gagtatggat accaatgctg acatctatga tcaaactgcc
    34801 tctacatttt ttcctaacgg agaagctatg tggaaaaaga tggtagaaga tcttaaaaag
    34861 gctgagaaat ttattttctt ggaatattac attatagaag aaggtttgat gtggaatcgc
    34921 atactagata tactagagca aaaggtagct cagggtgtag aggttaagat gctctatgat
    34981 gatatcggct gtatggctac tttaacagga gattatgcac atcgacttcg tcagctgggc
    35041 atcgaggccc ataaattcaa taaagttatt cctcgtttga cagtggctta taataacaga
    35101 gatcatagaa aaatattgat tgttgatggt cagatagcct atactggtgg ggtcaatctg
    35161 gcagatgagt acattaacca cgtcgagaga tttggttatt ggaaggatag tggaattcgc
    35221 ttagacggac tagcagtaaa agctctgaca cgcttatttt tgaccacttg gtacattaat
    35281 cgaggagaaa ttagtgattt tgatcaatat catttagaaa atcattctat cccgagtgac
    35341 ggtttaacca ttccatacgg aagtggaccc aagccaattt ttcgagcgca ggtagggaaa
    35401 aaagtttatc agagtttaat caatcaagca acagaatcgg tctatattac gacaccttat
    35461 ttgattatag attatgattt aacagagaca atcaaaaatg cagctatgag aggggtcgat
    35521 gttcgaatta tcacccctta cataccagat aagaagttca ttcagttagt cacgagagga
    35581 gcttatcccg accttctttc tgctggtgtt cggatttatg agtatagtcc aggttttatt
    35641 catagtaagc agatgttggt agacgaagat tttgcggtgg tggggacaat caatctcgac
    35701 taccggagct tggtacacca ttatgaaaat gcagtcttac tctataaaac tccttctata
    35761 agggaaatcg cccgagattt tcgaaatata tttgcagatt ctcaggaagt ctatcctcat
    35821 tctatcaaaa cgagctggta tcaaaagctt gtaaaagaaa tcgcccagct attcgcccct
    35881 atcttataag aaatctagaa cttaggatac aaaccagacc tatttttctt gtcttttacg
    35941 aatagaaaga aagaggaggg gaattcatgc taactaagga agaagtgaat gatatgattg
    36001 agttcaaaca gacacattta caccgctttc gggaaattga aacctttgtg aaactatgca
    36061 aaaaatcact caaacagcca tcgcaagctg acaatcctag gactttttga tatactaaga
    36121 cagataaatt gaacaggaga aacgatatga gtgtgtatgg tagagtagaa gaagttcata
    36181 aggagaatcg tgaacctcta gaataccaaa tcgaacaaga atcgcatcat cgtgaatcaa
    36241 gtcgtcttcc tttggtgaaa attttactat ggagtacgct tgtaacgggg ataactctag
    36301 gagtaccgct attactcgac ttaatgagtg cacaagaagt gcaggatttt tatgcaggtt
    36361 gggcgcttca tcagacaggg aagatttaca gcgactatta tggaagtcaa ggtttgcttt
    36421 attatttgct gacttacgtg agtcagggcg gatttttctt tgtcatcttt gagtggttag
    36481 ccttggtagc aggaggattt ttccttttta gatcagcgga caccttgaca gagcaaggag
    36541 accaagctgg acatctggtg actatttttt acatgctagt tacaggtctt gcttttggtg
    36601 gaggctatgc gactctttta gcgcttcctt tcttattcgc agcctttagt ttagttgcgg
    36661 cttacctaag caatccaagc catgataagg gatttgtacg gattgggcta gctttggcag
    36721 gcggattttt ctttgctccc ttatcatcgc tcctgtttat tgctgtagtg agtttaggct
    36781 tgttggtctt taaccttggg catagacgct ttgcgcatgg gttttatcag tttcttgcag
    36841 tggctttagg tttttcactt gtcttttatc caactgccta ctatagtgct gcaacaggaa
    36901 gttttgggga tgcgattagt ggtattcgtt atcctattga cagtattcgc tttgatttta
    36961 cttctaaaat tttagagaat atgttttttt atggcttgtt gtcccttggt ttgggatttg
    37021 tggtttgtat ctttttaggt ctctttcaat ccaaaccctt taaactatac gtcatttcgg
    37081 ttcctgcaag tcttgtggta attttaggtt tgattttact tttcttttca caagagcctc
    37141 tgcacgcttc ttatttgatg gtcgtcttcc ctgttttcct acttttattg gtaaccaata
    37201 ttaagagtca acagaggggg cgtagtgcta gaagaagccg aagagaaacg ccagttagcc
    37261 tatggagtcg tttcttcaaa ggaaatctat atctgctagt ttttgggttt gtctatcttt
    37321 tgtctgttcc ttttttgatg aagtttgtcc tttatccagt accttatcaa gaacgtaatc
    37381 gtcttgctga tttggtaaaa gaggagacaa atacggaaga tgctatctat gcatgggatg
    37441 atactgcgac tctttatcgt aagagtgagc gcttgtcgcc atcggcgatt ttgtccccgt
    37501 tgcactatac agcaactgag gaaaatcgta ataagttact taatgacttg aaagaaaaac
    37561 aacctaaggt gattgtggta aatgacaagg tggaagtctg gtctgaagtg gaaacactct
    37621 taaaagaaaa ttaccaacaa gtaaagactg attactcaga gtttaaagtc tataaaatta
    37681 aataaccaaa tcaatatctt gtgtattttt aaaaatttta agatttttaa cacaagatat
    37741 tgatttttct ttttagagtg gtataatact ttttagaaag aacattttag aaaagagcat
    37801 gcatatgatt gcactagaag aaaaaattac aattttgcca actctcttcg tcgagaaacg
    37861 agatgggaga cgtgttgtat ttgatgtgga caagattgac aaggctctct acaaggcagc
    37921 tgacaaggtt atggatgtga cacccctggt tgaaaaacgc ctcaatgatc tgactgagag
    37981 aattattaca gaaattcata gtcgctttcc acagggaatt aagatttacg aaattcaaaa
    38041 tatcgtagaa catgaactcc ttgaagccaa agaatatgcg ctggctgagg agtatattac
    38101 ttatcggaca cagagggatt ttgagcgctc aaaagcgacg gatatcaact ttagtattca
    38161 taaacttctc aacaaagacc agacagttgt caatgaaaat gctaataaag acagtgatgt
    38221 ctttaacact cagcgtgatt tgacagcagg gattgttggg aaatcaatcg gactgcaaat
    38281 gcttcctaag cacgtagcca atgcccacca aaagggggat atccactatc acgatttgga
    38341 ctacagtccc tataccccta tgaccaactg ctgtttgatt gattttaagg gtatgttgga
    38401 aaatggtttt aagattggaa atgcagaggt agagagtccc aagtctatcc agactgcgac
    38461 agcacagatt tctcaaatca ttgccaacgt tgcttctagc cagtacggtg gctgttcagc
    38521 tgaccgtatc gatgaaattt tggcgcctta tgcagagaag aactatcaaa aacatctcaa
    38581 agatgcagaa gagtgggtat tgcctgaaaa acgggaagat tacgcttgga agaaaacgca
    38641 aaaggacatc tacgatgcca tgcaatctct tgagtatgaa atcaatactc tcttcacttc
    38701 aaatggacaa acacctttta cttcgctagg ttttggtctg ggaaccagtc gttttgaacg
    38761 agaaattcaa aaagctattt taaacattcg catcaagggt cttggttcgg aacaccgtac
    38821 ggctatcttt cctaaactta ttttcactct gaaaagaggc cttaatttag aggaaggaac
    38881 tcccaactac gacatcaagc agttggctct tgagtgtgca accaaacgga tgtatccaga
    38941 tgttttatct tacgataaga ttgttgactt gacaggatcc ttcaaggtgc ctatgggttg
    39001 ccgttctttc ctccaaggat ggaaggatga aaatggtgta gaagtcaatt caggtcgcat
    39061 gaatctgggt gttgtgacgg ttaatctgcc tcgtattgct cttgagtctg aaggtgatat
    39121 gaataagttc tgggaaatct tcaacgagcg aatgaatatc gcagaagatg ctcttgttta
    39181 ccgtgtcgaa cgcactaaag aggcgacacc agcgaatgct cctatccttt atcagtacgg
    39241 tgcttttggc catcgtctag gtaaagaaga aagtgttgac cagctcttta agaatcgtcg
    39301 tgcgaccgtt tcgctgggct atatcggctt gtatgaagta gcgacagttt tctttggtaa
    39361 cagctgggaa agtaatccag atgctaagga attcacgcta gacatcattc acgatatgaa
    39421 acgccgtgta gaagagtggt cagaccaata tggctaccat ttctctatct actcaacacc
    39481 atccgaaagt ctgacagacc gtttctgccg actagatata gacaagtttg gctctattcc
    39541 tgatatcaca gacaaggaat actacaccaa ctctttccac tacgatgttc gtaaaaatcc
    39601 aacaccgttt gaaaaattgg actttgagaa agtctatcca gaagcaggtg cgtcaggtgg
    39661 tttcatccat tattgtgagt atccagtcct tcagcaaaat ccaaaggcct tggaagctgt
    39721 ctgggattat gcttatgacc gtgtaggcta tctaggcacc aatactccga ttgaccgttg
    39781 ctacaagtgt gactttgaag gggattttga accaactgag agagggtttg cttgtccaaa
    39841 ctgtggcaat agcgacccta aaacagtaga tgtggtgaag cgaacttgtg gctacctagg
    39901 taatcctcaa gcaagaccga tggtcaacgg gcgtcacaag gaaatcgctg cgcgtgtcaa
    39961 acatatgaat ggttcaacga ttaaaatagc tgggcatcaa gtaacaaatt agaaagaaat
    40021 gaaatgggaa aatatcaact agacgataag gggcgcgcac aagtgacccg ttatcacgag
    40081 aaacactcta aaggtggagc tggtaagaaa gaacgcttgc ttagcttcag agaacaattt
    40141 ttaaacaaga acaagaaaaa ataaaagtga gagccagctc tcgcttttct catagtggga
    40201 ggtaaggatg gaattacgca gaccaagatt agcggataag aaagctgttt tagatatgat
    40261 gacagagttt gaaaagagcc aatcagccca tgatggagga ttttgggata cagagaattt
    40321 tgtgtatgaa gagtggttgg aaagcaatca ggaacaggaa atggggatta atctgcctga
    40381 aggatgggtt cctgcaattc agttagtggc tttttctgag aaaggtcaag cagttggatt
    40441 tcttaatctc cggttgcgcc tcagtaactt tttactagaa gaaggtgggc acattggcta
    40501 ctccatccgt ccatctgaaa gaggcaaggg ttatgcaaaa gagactctcc gtcagggctt
    40561 gcaagttgct aaggaaaaga acatcaagaa agctctggtg acctgtagcg tgaataatcc
    40621 tgctagcaga gcagtcattc tagcaaatgg tggaatattt gaggatgctc acaatggagt
    40681 cgagcgttat tggatagagg tagcgaatga ataatccaaa accacaagaa tggaaaagcg
    40741 aggaacttag tcaaggtcgt atcattgact acaaggcctt taactttgtt gatggcgaag
    40801 gcgtgcgtaa ctctctctat gtagcaggct gtatgtttca ctgcgaggga tgttataatg
    40861 ttgcgacttg gtcttttaat gctggcattc cctatacagc agaattagaa gagcagatca
    40921 tggcagacct tgcccaaccc tatgttcaag gcttgacttt gctgggaggg gaaccttttc
    40981 tcaatactgg cattctcttg cctctagtta aacgcatccg aaaggaattg tcagacaagg
    41041 acatttggtc ctggacgggc tacacttggg aagaaatgat gttggaaact ccagataaac
    41101 tggaactctt atcattgatt gacattcttg tcgatggacg atacgatcga actaagagaa
    41161 atctcatgct ccagtttcga ggttcgtcca accaacgaat tatcgatgtg caaaaatcgc
    41221 tcaaaagtgg gcaagtagtg atttgggaca agctcaatga cggaaaagaa agctatgaac
    41281 aggtgaagag agaatgaaga aaaaagactt agtagaccaa ctagtctcag agatcgagac
    41341 ggggaaagtc aggacactgg gaatatacgg tcatggagct tcaggtaaat caacctttgc
    41401 acaggaattg taccaagctt tagattctac tacagtaaat ttgctagaaa cagatcccta
    41461 tatcacctca ggacgccatc tggtagtacc caaggacgcg ccgaatcaaa aggtgacagc
    41521 cagtctgcca gtggcgcatg aactggagag tttgcagaga gatatccttg ccttgcaggc
    41581 gggtatggat gtcttgacaa ttgaagaacc ttggaaggct agtgaggtct tgtctggagc
    41641 caaaccaatt ttgattgtcg aagggatgtc tgttggcttt ctacccaagg aactctttga
    41701 aaaaaccatc tgtttctaca cggatgagga gaccgaatta aagcgacgcc ttgctagaga
    41761 tacgactgtg agaaatcgcg atgcatcctt tatattggct agccatcaga tgagacggga
    41821 gcagtatctg cgatactata aagaaactga gtctaaggcg gatatcttag tggaccaatc
    41881 agaagataaa tttgatgtca agaggactta acttatgtat agaagaaata tagaagaaaa
    41941 tccctaattt tagaaagaaa aagtaggaaa acagtttcat ccccaaaaaa cgaaaaaacc
    42001 taacaaatcc cttgcaatcg caggggattt gtgttattct attatggtgc tgtaaattac
    42061 agccttagtt ttgatgcaag aggttgcgac acgctcggtt gcattgccac gcaacaccgc
    42121 gtcggttttc ttgtggagct agcctattat cttaaataga cgaaaaggag aaaaagatgg
    42181 caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca ccgtacgctt gacacagcgg
    42241 ctgcaaaaat cgtagaatca gctactcgta caggtgcaca agttgcgggt ccaatcccac
    42301 ttccaactga acgtagcctc tacacaatca ttcgtgcgac tcacaaatac aaagactctc
    42361 gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga tatcgttaac ccaactcaaa
    42421 aaacagttga tgccttgatg aaattggatc ttccaagtgg tgtaaacgta gaaatcaaac
    42481 tttaatctaa aatataaaag agcagaggct ggtgtttcaa tctaattgaa cacgggctaa
    42541 acttggtgtg aaaaagataa acttcctcgc gtctgctaga cactgtgtca gtttcctatt
    42601 ttcacgttga gtttgacgcc ctttgtatct tagacttgag cataaaaaac gctcgttaaa
    42661 aactttttga ataaaaatat agaaaaggaa ctattttctc atgacaaaag gaatcttagg
    42721 gaaaaaagtg ggaatgactc aaatcttcac tgaagctggc gaattgatcc ctgtaacagt
    42781 tattgaagca actccaaacg ttgttcttca agttaaaact gttgaaacag acggatacaa
    42841 cgctatccaa gttggtttcg atgacaaacg cgaagtattg agcaacaaac ctgctaaagg
    42901 acatgtagcg aaagctaaca cggctcctaa gcgcttcatt cgtgaattca aaaacgttga
    42961 aggcttggaa gttggtgctg aaattacagt tgaaacattc gcagctggag atgttgttga
    43021 tgtaactggt acttctaaag gtaaaggttt ccaaggtgtt atcaagcgcc acggacaatc
    43081 acgtggaccg atggctcacg gttctcgtta ccaccgtcgt ccaggttcta tgggacctgt
    43141 tgcacctaac cgcgtattca aaggtaaaaa ccttgcagga cgtatgggtg gtgaccgcgt
    43201 aacaattcaa aatcttgaag ttgtacaagt tgttccagaa aagaacgtta tccttatcaa
    43261 aggtaacgta ccaggtgcta agaaatctct tatcactatc aaatcagcag ttaaagctgg
    43321 taaataataa agaaagggga aatcagtcac aatggcaaac gtaacattat ttgaccaaac
    43381 tggtaaagaa gctggccaag ttgttcttaa cgatgcagta tttggtatcg aaccaaatga
    43441 atcagttgtg tttgatgtaa tcatcagcca acgcgcaagc cttcgtcaag gaacacacgc
    43501 tgttaaaaac cgctctgcag tatcaggtgg tggacgcaaa ccgtggcgtc aaaaaggaac
    43561 tggacgtgct cgtcaaggtt ctatccgctc accacaatgg cgtggtggtg gtgttgtctt
    43621 cggaccaact ccacgttcat acggctacaa acttccacaa aaagttcgtc gcctagctct
    43681 taaatcagtt tactctgaaa aagttgctga aaacaaattc gtagctgtag acgctctttc
    43741 atttacagct ccaaaaactg ctgaatttgc aaaagttctt gcagcattga gcatcgattc
    43801 taaagttctt gttatccttg aagaaggaaa tgaattcgca gctctttcag ctcgtaacct
    43861 tccaaacgtg aaagttgcaa ctgctacaac tgcaagtgtt cttgacatcg caaatagcga
    43921 caaacttctt gtcacacaag cagctatctc taaaatcgag gaggttcttg cataatgaat
    43981 ttgtatgatg ttatcaaaaa acctgtcatc actgaaagct caatggctca acttgaagca
    44041 ggaaaatatg tatttgaagt tgacactcgt gcacacaaac ttttgatcaa gcaagctgtt
    44101 gaagctgctt tcgaaggtgt taaagttgcc aatgttaaca caatcaacgt aaaaccaaaa
    44161 gctaaacgtg ttggacgtta cactggtttt actaacaaaa ctaaaaaagc tatcatcaca
    44221 cttacagctg attctaaagc aatcgagttg tttgctgctg aagctgaata atctaaggag
    44281 gaaatatcgt gggaattcgt gtttataaac caacaacaaa cggtcgccgt aatatgactt
    44341 ctttggattt cgctgaaatc acaacaagca ctcctgaaaa atcattgctt gttgcattga
    44401 agagcaaggc tggtcgtaac aacaacggtc gtatcacagt tcgtcaccaa ggtggtggac
    44461 acaaacgttt ctaccgtttg gttgacttca aacgtaataa agacaacgtt gaagcagttg
    44521 ttaaaacaat cgagtacgat ccaaaccgtt ctgcaaacat cgctcttgta cactacactg
    44581 acggtgtgaa agcatacatc atcgctccaa aaggtcttga agtaggtcaa cgtatcgttt
    44641 caggtccaga agcagatatc aaagtcggaa acgctcttcc acttgctaac atcccagttg
    44701 gtactttgat tcacaacatc gagttgaaac caggtcgtgg tggtgaattg gtacgtgctg
    44761 ctggtgcatc tgctcaagta ttgggttctg aaggtaaata cgttcttgtt cgtcttcaat
    44821 caggtgaagt tcgtatgatt cttggaactt gccgtgctac agttggtgtt gtcggaaacg
    44881 aacaacatgg acttgtaaac cttggtaaag caggacgtag ccgttggaaa ggtatccgcc
    44941 caacagttcg tggttctgta atgaacccta acgatcaccc acacggtggt ggtgaaggta
    45001 aagcaccagt tggtcgtaaa gcaccatcta ctccatgggg caaacctgct cttggtctta
    45061 aaactcgtaa caagaaagcg aaatctgaca aacttatcgt tcgtcgtcgc aacgagaaat
    45121 aatattaaac tagtcgctta agcaactagt aaatccgcca gctcggtagc gctccatagg
    45181 agtgcaagcc gctgtggtac aacatttaaa ggagaaaata taaaaatggg acgcagtctt
    45241 aaaaaaggac ctttcgtcga tgagcatttg atgaaaaaag ttgaagctca agctaatgac
    45301 gaaaagaaaa aagttattaa aacttggtca cgtcgttcaa cgatcttccc aagtttcatt
    45361 ggttacacta ttgcagttta tgacggacgt aaacacgtac ctgtttacat ccaagaagac
    45421 atggtaggcc acaaacttgg tgaatttgca ccaactcgta cttacaaagg tcacgctgca
    45481 gacgacaaga aaacacgtag aaaataagga gaacataaat ggcagaaatt acttcagcta
    45541 aagcaatggc tcgtacagta cgtgtttcac ctcgtaaatc acgtcttgtt cttgataaca
    45601 tccgtggtaa aagcgtagcc gatgcaatcg caatcttgac attcactcca aacaaagctg
    45661 ctgaaatcat cttgaaagtt ttgaactcag ctgtagctaa cgctgaaaac aactttggtt
    45721 tggataaagc taacttggta gtatctgaag cattcgcaaa cgaaggacca actatgaaac
    45781 gtttccgtcc acgtgcgaaa ggttcagctt caccaatcaa caaacgtaca gctcacatca
    45841 ctgtagctgt tgcagaaaaa taaggaggta aaatcgtggg tcaaaaagta catccaattg
    45901 gtatgcgtgt cggcatcatc cgtgattggg atgccaaatg gtatgctgaa aaagaatacg
    45961 cggattacct tcatgaagat cttgcaatcc gtaaattcgt tcaaaaagaa cttgctgacg
    46021 cagcagtttc aactattgaa atcgaacgcg cagtaaacaa agttaacgtt tcacttcaca
    46081 ctgctaaacc aggtatggtt atcggtaaag gtggtgctaa cgttgatgca ctccgtgcaa
    46141 aacttaacaa attgactgga aaacaagtac acatcaacat catcgaaatc aaacaacctg
    46201 atttggatgc tcaccttgta ggtgaaggaa ttgctcgtca attggagcaa cgtgttgctt
    46261 tccgtcgtgc acaaaaacaa gcaatccaac gtgcaatgcg tgctggagct aaaggaatca
    46321 aaactcaagt atcaggtcgt ttgaacggtg cagatatcgc ccgtgctgaa ggatactctg
    46381 aaggaactgt tccgcttcac acacttcgtg cagatatcga ttacgcttgg gaagaagcag
    46441 atactacata cggtaaactt ggtgttaaag tatggatcta ccgtggtgaa gttcttccag
    46501 ctcgtaaaaa cactaaagga ggtaaataac caatgttagt acctaaacgt gttaaacacc
    46561 gtcgtgagtt ccgtggaaaa atgcgcggtg aagcaaaagg tggaaaagaa gtagcattcg
    46621 gtgaatacgg tcttcaagct acaactagcc actggatcac taaccgccaa atcgaagctg
    46681 ctcgtatcgc catgactcgt tacatgaaac gtggtggtaa agtttggatt aaaatcttcc
    46741 cacacaaatc atacactgct aaagctatcg gtgtgcgtat gggatctggt aaaggggcac
    46801 ctgaaggttg ggtagcacca gttaaacgtg gtaaagtgat gttcgaaatc gctggtgtat
    46861 ctgaagagat tgcacgtgaa gcgcttcgac ttgctagcca caaattgcca gttaaatgta
    46921 aattcgtaaa acgtgaagca gaataaggag aaggcatgaa acttaatgaa gtaaaagaat
    46981 ttgttaaaga acttcgtggt ctttctcaag aagaactcgc gaagcgcgaa aacgaattga
    47041 aaaaagaatt gtttgaactt cgtttccaag ctgctactgg tcaattggaa caaacagctc
    47101 gcttgaaaga agttaaaaaa caaatcgctc gtatcaaaac agttcaatct gaagcgaaat
    47161 aatagactag ggaaggagaa atttcaatgg aacgcaataa tcgtaaagtt cttgttggac
    47221 gtgttgtatc tgacaaaatg gacaagacaa tcacagttgt agttgaaaca aaacgtaacc
    47281 acccagtcta tggtaaacgt attaactact ctaaaaaata caaagctcat gatgaaaaca
    47341 atgttgccaa agaaggcgat atcgtacgta tcatggaaac tcgcccgctt tcagctacaa
    47401 aacgtttccg tcttgtagaa gttgttgaag aagcggtcat catctaatca aacctgaaag
    47461 gagaaaactg aaatgattca aacagaaact cgtttgaaag tcgcagacaa cagcggtgct
    47521 cgcgaaatct tgactatcaa agttcttggt ggttcaggac gtaaatttgc aaacatcggt
    47581 gatgttatcg tggcatctgt aaaacaagct actcctggtg gtgcggttaa aaaaggtgac
    47641 gttgttaaag cagttatcgt tcgtactaaa tcaggtgctc gtcgtgctga tggttcatac
    47701 atcaaatttg acgaaaacgc agcagttatc atccgtgaag acaaaactcc tcgcggaaca
    47761 cgtatctttg gcccagttgc acgtgaattg cgtgaaggtg gcttcatgaa gatcgtgtca
    47821 cttgctccag aagtacttta atttttagga acaaactagt cccctagctt caagctaggg
    47881 tgcccttatg ggcgtaagaa aaatcaagga gaaacctaat gtttgtaaaa aaaggcgaca
    47941 aagttcgcgt aatcgctggt aaagacaagg gaacagaagc tgttgtcctt actgcccttc
    48001 caaaagtaaa caaagttatc gttgaaggtg ttaacattgt taagaaacac caacgtccaa
    48061 ctaacgagct tcctcaaggt ggtatcatcg agaaagaagc agctatccac gtatcaaacg
    48121 ttcaagtttt ggacaaaaat ggtgtagctg gtcgtgttgg atacaaattt gtagacggta
    48181 aaaaagttcg ctacaacaaa aaatcaggcg aagtgcttga ttaatcacga aggaaaggag
    48241 aagtataatg gcaaatcgtt taaaagaaaa atatcttaat gaagtagttc ctgctttgac
    48301 agaacaattc aactactcat cagtgatggc tgtgcctaaa gtagataaga ttgttttgaa
    48361 catgggtgtt ggtgaagctg tatcaaacgc taaaagcctt gaaaaagctg ctgaagaatt
    48421 ggcacttatc tcaggtcaaa aaccacttat cactaaagct aaaaaatcaa tcgccggctt
    48481 ccgtcttcgt gaaggtgttg cgatcggtgc aaaagttacc cttcgtggtg aacgtatgta
    48541 cgaattcttg gataaattgg tatcagtttc acttccacgt gtacgtgact tccacggtgt
    48601 cccaacaaaa tcatttgatg gacgcgggaa ctacacactt ggtgtgaaag aacaattaat
    48661 cttcccagaa atcaacttcg atgacgttga caaaactcgt ggtcttgaca tcgttatcgt
    48721 aacaactgct aacactgacg aagagtcacg tgcattgctt acaggccttg gaatgccttt
    48781 tgcaaaataa tataggaggt aaatctaatg gctaaaaaat caatggtagc tagagaggct
    48841 aaacgccaaa aaattgttga ccgttatgct gaaaaacgtg ctgcattaaa ggcggcaggg
    48901 gactacgaag gtttatctaa attacctcgc aacgcctcac cgactcgttt acataatcgt
    48961 tgtagagtta cggggcgccc acattcagtt taccgcaaat ttggtctgag tcgtatcgct
    49021 tttcgcgaac ttgcgcataa aggtcaaatt cctggtgtaa caaaagcatc ttggtaattt
    49081 aagatatcaa gggtgtcaaa actccaagta aaaataggaa acttgacgaa gaaactaaag
    49141 tttctaggaa agtttatctt tttcacacag agtttagccc gggttcaatt gggcttgcca
    49201 atttgaaccc gagctacagc tttggcaaaa aagaccaatt tgctttggag cattgcttct
    49261 gcattaaatt gtctattttt gctcgtgctg ttacgctctt tgtatcatgt attaactagc
    49321 aagtgcaact tgcaaactac tagtaagagg agaaaaacaa aatggttatg actgacccaa
    49381 tcgcagactt cctaactcgt attcgtaatg ctaaccaagc taaacacgaa gtacttgaag
    49441 tacctgcatc aaacatcaaa aaagggattg ctgaaatcct taaacgcgaa ggttttgtaa
    49501 aaaacgttga aatcattgaa gatgacaaac aaggcgtcat ccgtgtattt cttaaatacg
    49561 gatcaaatgg tgagaaagtt atcactaact tgaaacgtgt ttctaaacca ggacttcgtg
    49621 tctacaaaaa acgtgaagac cttccaaaag ttcttaacgg acttggaatt gccatccttt
    49681 caacttctga aggtttgctt actgataaag aagcacgcca aaagaatgtt ggtggtgagg
    49741 ttatcgctta cgtttggtaa aatcaagata caaagctcgt aaagaacaaa gcaaaattag
    49801 gaagttggag aagtttgttt acaaacaagc caacttatct attttgcaca gttcttagag
    49861 cgtgttcagt tcagctcttg aactaaataa gtatctgaac cccgtgaaaa ctggccgttc
    49921 tggcctgaca atttaacagg agaaaataaa catgtcacgt attggtaata aagttatcgt
    49981 gttgcctgct ggtgttgaac tcgctaacaa tgacaacgtt gtaactgtaa aaggacctaa
    50041 aggagaactt actcgtgagt tctcaaaaga tattgaaatc cgtgtggaag gtactgaaat
    50101 aactcttcac cgtccaaacg attcaaaaga aatgaaaact atccacggaa ctactcgtgc
    50161 ccttttgaac aacatggttg ttggtgtatc agaaggattc aagaaagaac ttgaaatgcg
    50221 tggggttggt taccgtgcac agcttcaagg atctaaactt gttttggctg ttggtaaatc
    50281 tcatccagac gaagttgaag ctccagaagg aattactttt gaacttccaa acccaacaac
    50341 aatcgttgtt agcggaattt caaaagaagt agttggtcaa acagctgctt acgtacgtag
    50401 ccttcgttca ccagaaccat ataaaggtaa aggtatccgt tacgttggtg aattcgttcg
    50461 ccgtaaagaa ggtaaaacag gtaaataatg ttgagtggtt gatcatcaac caccaaccta
    50521 ttttccaact ttgtgcatag cacacgattt aaaactaaag aggtgaaaac tgtgatttca
    50581 aaaccagata aaaacaaact ccgccaaaaa cgccaccgtc gcgttcgcgg aaaactctct
    50641 ggaactgctg atcgcccacg tttgaacgta ttccgttcta atacaggcat ctacgctcaa
    50701 gtgattgatg acgtagcggg tgtaacgctc gcaagtgctt caactcttga taaagaagtt
    50761 tcaaaaggaa ctaaaactga acaagccgtt gctgtcggta aactcgttgc agaacgtgca
    50821 aacgctaaag gtatttcaga agtggtgttc gaccgcggtg gatatctata tcacggacgt
    50881 gtgaaagctt tggctgatgc agctcgtgaa aacggattga aattctaata ggaggacact
    50941 agaaaatggc atttaaagac aatgcagttg aattagaaga acgcgtagtt gctgtcaacc
    51001 gtgttacaaa agttgttaaa ggtggacgtc gtcttcgttt cgcagctctt gttgttgttg
    51061 gtgaccacaa tggtcgcgta ggatttggta ctggtaaagc tcaagaagtt ccagaagcaa
    51121 ttcgtaaagc agtagatgat gctaagaaaa acttgatcga agttcctatg gttggaacaa
    51181 caatcccaca cgaagttctt tcagaattcg gtggagctaa agtattgttg aaacctgctg
    51241 tagaaggttc tggagttgcc gctggtggtg cagttcgtgc cgttgtggaa ttggcaggtg
    51301 tggcagatat tacatctaaa tcacttggtt ctaacactcc aatcaacatt gttcgtgcaa
    51361 ctgttgaagg tttgaaacaa ttgaaacgcg ctgaagaaat tgctgccctt cgtggtattt
    51421 cagtttctga tttggcataa gaaaggggat aaaatggctc aaattaaaat tactttgact
    51481 aagtctccaa tcggacgcat tccatcacaa cgtaaaactg ttgtagcact tggacttggc
    51541 aaattgaaca gctctgttat taaagaagat aacgctgcta tccgtggtat gattacagca
    51601 gtatctcact tagtaacagt tgaagaagta aactaatgaa gttttagggg atgtgcactg
    51661 taccatcccc taaaactaga tatagtcatc tatgatgaca tcgtataggc gagttgatgg
    51721 gggagacaac cttttctccc ttatcggcgc tagcatttta caaaagagga gaaaataaaa
    51781 atgaaacttc atgaattgaa acctgcagaa ggttctcgta aagtacgtaa ccgcgttggt
    51841 cgtggtactt catcaggtaa cggtaaaaca tctggtcgtg gtcaaaaagg tcaaaaagct
    51901 cgtagcggtg gcggagttcg ccttggtttt gaaggtggac aaactccatt gttccgtcgt
    51961 cttccaaaac gtggattcac taacatcaac gctaaagaat acgcaattgt gaaccttgac
    52021 caattgaacg tctttgaaga tggtgctgaa gtaactccag ttgttcttat cgaagcagga
    52081 attgttaaag ctgaaaagtc aggtattaaa attcttggta acggtgagtt gactaagaaa
    52141 ttgactgtga aagcagctaa attctctaaa tcagctgaag aagctatcac tgctaaaggt
    52201 ggttcagtag aagtcatcta agagaggtga cctatgtttt ttaaattatt aagagaagct
    52261 cttaaagtca agcaggttcg atcaaaaatt ttatttacaa tttttatcgt tttggtcttt
    52321 cgtatcggaa ctagcattac agttcctggt gtgaatgcca atagcttgaa tgctttaagt
    52381 ggattatcct tcttaaacat gttgagcttg gtgtcgggga atgccctaaa aaacttttcg
    52441 atttttgccc taggagttag tccctatatc accgcttcta ttgttgtcca actcttgcaa
    52501 atggatattt tacccaagtt tgtagagtgg ggtaaacaag gggaagtagg tcgaagaaaa
    52561 ttgaatcaag ctactcgtta tattgctcta gttctcgctt ttgtgcaatc tatcgggatt
    52621 acagctggtt ttaatacctt ggctggagct caattgatta aaactgcttt aactccacaa
    52681 gtttttctga cgattggtat catcttaaca gctggtagta tgattgtcac ttggttgggt
    52741 gagcaaatta cagataaggg atacggaaac ggtgtttcca tgattatctt tgccgggatt
    52801 gtttcctcaa ttccagagat gattcagggc atctatgtgg actactttgt gaacgtccca
    52861 agtagccgta tcacttcatc tatcattttc gtaatcattt tgattattac tgtattgttg
    52921 attatttact ttacaactta tgttcaacaa gcagaataca aaattccaat ccaatatact
    52981 aaggttgcac aaggtgctcc atctagctct taccttccgt taaagataaa tcctgctgga
    53041 gttatccctg ttatctttgc cagttcgatt actgcagcgc ctgcggctat tcttcagttt
    53101 ttgagtgcca caggtcatga ttgggcttgg gtaagggtag cacaagagat gttggcaact
    53161 acttctccaa ctggtattgc catgtatgct ttattgatta ttctctttac attcttctat
    53221 acgtttgtac agattaatcc tgaaaaagca gcagagagcc tacaaaagag tggtgcctat
    53281 atccatggag ttcgtcctgg taaaggtaca gaagaatata tgtctaaact tcttcgtcgt
    53341 cttgcaactg ttggttccct cttccttggt gtgatttcca ttttaccgat tgcagctaaa
    53401 gatgtatttg gtctttctga tgttgttgcc tttggtggaa caagtctctt gatcattatc
    53461 tctacaggta tcgaaggaat caagcaattg gaaggttacc tattgaaacg taagtatgtt
    53521 ggtttcatgg acagaacaga ataaaagtat ttactgaatc agtaaatgct gagggagtgg
    53581 aggtttaaac tctgacattt gtaagagttg gatctcccct cttctatttt gtttttaaat
    53641 aggggtgaaa agactttttg cttctattta aaaataaaat aaggagatca aatcatgaat
    53701 cttttgatta tgggcttacc tggtgcaggt aagggaactc aagcagcaaa aatcgtagaa
    53761 caattccatg ttgcacatat ctcaacaggt gatatgttcc gcgctgcaat ggcaaatcaa
    53821 actgaaatgg gtgttcttgc taagtcatat attgacaagg gtgaattggt tcctgacgaa
    53881 gttacaaatg gaatcgtaaa agaacgcctt tcacaagatg atattaaaga aacaggattc
    53941 ttattggatg gttacccacg tacaattgaa caagctcatg ccttggacaa aacattggct
    54001 gaacttggca ttgaactaga aggtgttatc aatattgaag tgaactctga cagcctcttg
    54061 gaacgtttga gtggccgtat catccaccgc gtaactggag aaactttcca caaggtcttt
    54121 aacccaccag ttgactataa agaagaagat tactaccaac gtgaagatga taagcctgag
    54181 acagtaaaac gtcgtttgga tgttaatatt gctcaaggag aaccaatcat tgctcactac
    54241 cgtgccaaag gtttggttca tgacatcgaa ggtaatcaag atatcaatga tgtcttctca
    54301 gatattgaaa aagtattgac aaatttgaaa taaagcgttt ttcatacttg caaaaattcg
    54361 ctataaatgt tatactgaga tagtctgact tataattgtt gtctctgtgt ctagaggcat
    54421 cgaatcgaaa tttatggagg tgcttttgcg tggcaaaaga cgatgtgatt gaagttgaag
    54481 gcaaagtagt tgatacaatg ccgaatgcaa tgtttacggt tgaacttgaa aatggacatc
    54541 agattttagc aacagtttct ggtaaaattc gtaaaaacta tattcgtatt ttagcgggag
    54601 atcgtgttac tgtcgaaatg agtccatatg acttgacacg tggacgtatc acttaccgct
    54661 ttaaataatc gaaaaacttg gagggataag aaatgaaagt aagaccatcg gtcaaaccaa
    54721 tttgcgaata ctgtaaagtt attcgtcgta atggtcgtgt tatggtaatt tgcccagcaa
    54781 atccaaaaca caaacaacgt caaggataag atagaaagga gaaaacatgg ctcgtattgc
    54841 tggagttgat attccaaatg acaaacgcgt agtaatctca ttgacttatg tttatggtat
    54901 cggacttgca acatctaaga aaattttggc tgctgctgga atctcagaag atgttcgtgt
    54961 acgtgatctt acatcagatc aagaagatgc tatccgtcgt gaagtggatg caatcaaagt
    55021 tgaaggtgac cttcgtcgtg aagtaaactt gaacatcaaa cgtttgatgg aaatcggttc
    55081 ataccgtggt atccgtcacc gtcgtggact tcctgtccgt ggacaaaaca ctaaaaacaa
    55141 cgctcgcact cgtaaaggta aagctgttgc gattgctggt aagaaaaaat aatataggag
    55201 gtaaaagtct tggctaaacc aacacgtaaa cgtcgtgtga aaaagaatat cgaatctggt
    55261 attgctcata ttcacgctac atttaataac actattgtta tgattactga tgtgcatggt
    55321 aatgcaattg cttggtcatc agctggtgct cttggtttca aaggttctcg taaatctaca
    55381 ccattcgctg ctcaaatggc ttctgaagct gctgctaaat ctgcacaaga acacggtctt
    55441 aaatcagttg aagttactgt aaaaggtcca ggttctggtc gtgagtcagc tattcgtgcg
    55501 cttgctgccg ctggtcttga agtaacagca attcgtgatg tgactccagt gccacacaat
    55561 ggtgctcgtc ctccaaaacg tcgccgtgta taatcatcgc attacactgc ttttcgttta
    55621 agagggagta actaaatgat cgagtttgaa aaaccaaata taacaaaaat tgatgaaaat
    55681 aaagattatg gcaagtttgt aatcgaacca cttgaacgtg gctacggtac aactcttggt
    55741 aactctcttc gtcgtgtact tctagcttct ctaccaggag cagctgtgac atctatcaac
    55801 attgatggtg tgttacatga gtttgacaca gttccaggtg ttcgtgaaga cgtgatgcaa
    55861 atcattctga acattaaagg aattgcagtg aaatcgtacg ttgaagacga aaaaatcatc
    55921 gaactggatg ttgaaggtcc tgctgaagta acagctggtg acattttgac agatagcgat
    55981 attgaaattg taaatccaga tcattatctc tttacaatcg gtgaaggttc ttctctaaaa
    56041 gcgactatga ctgttaacag tggtcgtgga tatgtacctg ctgatgaaaa taaaaaggat
    56101 aatgcaccag ttggaacact tgctgtagat tctatttata caccagttac aaaagtcaac
    56161 tatcaagtgg aacctgctcg tgtaggtagc aatgatggtt ttgacaaatt aacccttgaa
    56221 atcttgacaa atggaacaat tattccagaa gatgctttag ggctttcagc acgtattttg
    56281 acagaacatc ttgatttgtt tacaaatctt actgagattg ctaagtcaac tgaagtgatg
    56341 aaagaagctg atactgaatc tgacgaccgt attttagatc gtacgattga ggaactggac
    56401 ttgtctgtgc gttcatacaa ctgtttaaaa cgtgccggta tcaatactgt gcatgatttg
    56461 acagaaaaat ctgaagcaga gatgatgaaa gtacgaaatc ttggacgcaa gagtttggaa
    56521 gaagtgaaac tcaaactcat tgatttgggt cttggattaa aagataaata aaggaggaat
    56581 acatggctta ccgtaaacta ggacgcacta gctcacaacg taaagcaatg cttcgcgatt
    56641 tgacaactga ccttttgatc aacgaatcaa tcgtgacaac tgaagctcgt gctaaagaaa
    56701 tccgtaaaac tgttgaaaaa atgattactc taggtaaacg tggtgatttg catgcacgtc
    56761 gtcaagcagc tgctttcgta cgtaatgaaa tcgcatctga aaactatgat gaagcaactg
    56821 ataagtacac ttctactaca gcacttcaaa aattgttctc agaaatcgca cctcgttatg
    56881 ctgaacgtaa cggtggatac actcgtatcc ttaaaactga accacgtcgt ggtgatgcag
    56941 cgccaatggc gatcatcgaa ttagtataaa atcatcaatt ttgttgagtg ttatgatgat
    57001 ggagtcttgt gctcttagtc tagctctggt ctaccgctag gatttcggtc ctagcgggaa
    57061 cactcatcat aagttgggat agtagacgct tgtttacgaa attgtttttt tcttaagaac
    57121 aacttcgtaa gcaggcgttt ttgagtattt tcgttagaat tatgctatac tatttgaaaa
    57181 gaatcctgtt taatgttaag gtttcttatt ttaagaagaa ttggagttta cttatgaaag
    57241 ccattataac tgttgttggt aaagataaat ctggaattgt tgcaggtgtt tctggtaaaa
    57301 ttgcagaatt aggattgaat attgacgata tctctcaaac tgtcttggat gaatatttta
    57361 cgatgatggc tgttgtatct agtgatgaaa agcaagattt tacctatctt cgtaatgaat
    57421 ttgaagcttt tgggcaaact ttgaatgtaa aaatcaatat tcagagtgca gcgattttcg
    57481 aagctatgta taatatctag gaggtcatca tggatattag acaagttact gaaaccatcg
    57541 ccatgattga ggagcaaaac ttcgatatta gaaccattac catggggatt tctcttttgg
    57601 actgtatcga tccaaatatc aatcgtgctg cggagaaaat ctatcaaaaa attacgacaa
    57661 aggcggctaa tttagtagct gttggtgatg aaattgcggc tgagttggga attcctatcg
    57721 ttaataagcg tgtatcggtg acacctattt ctctgattgg ggcagcgaca gatgcgacgg
    57781 actacgtggt tctggcaaaa gcgcttgata aggctgcgaa agagattggt gtggacttta
    57841 ttggtggttt ttctgcctta gtacaaaaag gttatcaaaa gggagatgag attctcatca
    57901 attccattcc tcgcgctttg gctgagacgg ataaggtctg ctcgtcagtc aatatcggct
    57961 caaccaagtc tggtattaat atgacggctg tggcagatat gggacgaatt atcaaggaaa
    58021 cagcaaatct ttcagatatg ggagtggcca agttggttgt attcgctaat gctgttgagg
    58081 acaatccatt tatggcgggt gcctttcatg gtgttgggga agcagatgtt atcatcaatg
    58141 tcggagtttc tggtcctggt gttgtgaaac gtgctttgga aaaagttcgt ggacagagct
    58201 ttgatgtagt agccgaaaca gttaagaaaa ctgcctttaa aatcactcgt atcggtcaat
    58261 tggttggtca aatggccagt gagagactgg gtgtggagtt tggtattgtg gacttgagtt
    58321 tggcaccaac ccctgcggtt ggagactctg tggcacgtgt ccttgaggaa atggggctag
    58381 aaacagttgg cacgcatgga acgacggctg ccttggccct cttgaacgac caagttaaaa
    58441 agggtggagt gatggcctgc aaccaagtcg gtggtttatc tggtgccttt atccctgttt
    58501 ctgaggatga aggaatgatt gctgcagtgc aaaatggctc tcttaattta gaaaaactag
    58561 aagctatgac ggctatctgt tctgttggat tggatatgat tgccatccca gaagatacgc
    58621 ctgctgaaac tattgcggct atgattgcgg atgaagcagc aatcggtgtt atcaacatga
    58681 aaacaacagc tgttcgtatc attcccaaag gaagagaagg cgatatgatt gagtttggtg
    58741 gtctattagg aactgcaccc gttatgaagg ttaatggggc ttcgtctgtc gacttcatct
    58801 ctcgcggtgg acaaatccca gcaccaattc atagttttaa aaattaagaa aataggagaa
    58861 attttaagtt ctatttaaga ttagatgtgt atactataat cattaaataa agacctccta
    58921 atattatttg aaacagataa cactgaatta gtttgaattt gattttcatc taatatcttt
    58981 atttaatgaa ctcctaaact ttttcataat aatctccttc aaaagtcgcc tgtatgggtg
    59041 gcttttattt tatcattcat gatataatag aagcaaacgg aggacggaaa atggtaaaag
    59101 tacgattgta tttggtacgt catggcaaga ccatgtttaa cacgattggt cgcgcgcaag
    59161 gttggagcga tactccctta actgctgaag gtgaacgagg gattcaagag ttaggaatcg
    59221 gtttgcgaga atctgattta cagtttgagc gcgcttattc gagtgattct ggtcgtacca
    59281 ttcagaccat gggaattata cttgaagaac ttggcttgca ggggaaaatc ccttatcgca
    59341 tggacaagcg tatcagagaa tggtgtttcg gtagttttga tggagcctat gatggcgatc
    59401 ttttcatggg cattattcct cgtatcttta atgtggacca cgttcaccaa ttgtcttatg
    59461 ctgaactggc tgagggcttg gtagaggtcg atacagctgg ttgggctgaa ggttgggaaa
    59521 aactcagtgg ccgaatcaag gaaggctttg aaataattgc aaaagaaatg gaagatcaag
    59581 gtggaggtaa cgcccttgtt gtcagccatg gaatgactat tggaaccatt gtttatctga
    59641 ttaatggcat gcatccgcat ggtctagata atggtagcgt gacgattctt gaatatgagg
    59701 acggtcagtt tagggttgaa gttgtcggtg accgtagtta ccgagagcta ggacgtgaga
    59761 agatggaaga aggttctatt taatcagtct agacttgctt gccatgagct agggatttga
    59821 taagaatatc aagataagaa aaaacagccg agggtactcc tttcggctgt ttttgatgtg
    59881 gaaaactaaa gtgtaatgct attgctttta gagattttca taaacaagag caaggaacct
    59941 actgttagaa cagtcaggat agttgacaag gctgcggcta caccgtaatt tcctctgaga
    60001 acctctgtat aaatagctac agtcattgtt cttgttttga cattgtagag gaggatagaa
    60061 gtagagagtt ttgaaatcat tgtgacccaa gataagatgg ctccagaaat gataccagat
    60121 agcatcattg gagttgtaat cttagcaaag atattgagac gactacttcc taagctttca
    60181 gcagcttctt caatacttgg tgctatttgt tgtaagctag caacagatga gcgaatagta
    60241 taaggtaatc ttctgacaga tagagacata atcaagatga aagcagtccc tgtaatcata
    60301 agaaatccac ttccaaatag accagtattg aaggaagaaa tgaaggcaat ccctagaacg
    60361 gttcctggta caatataagg taccatactg aggctgtcaa ttaagtttgt aaacaaattc
    60421 cgttttctaa cggctaggta ggagataaat gtcgcaaata gaacaactag aactaaggca
    60481 atcaaaggga tacgaatggt attgaaaata gcagatccca tacgattgaa agctaccttg
    60541 taactgtttg gagaataacc tttaacaaat accatacctg atgtttttag gaaagaggta
    60601 taaattaagt agatttgagg taaaacagag ataaagataa ttccgtagac tgttgcataa
    60661 atggcagcca tttttccttt tgtagttttt ttaggctcaa ttggatggat cagattcatg
    60721 ctgaaactgt agcggtttgc aatgtgtttt tggataagga aaattgccaa ggcaatgata
    60781 atcgccataa ttgcaaaagc agaatttcct ccaacctcgc taataaattg ggtataaatc
    60841 aggacaggga aagtccgata tccttcgcca atcaacatag gcgttccaaa gtctgagaat
    60901 gctctcataa atacaagcaa ggagctgcta gtaaggttgg aactagaaga ggtaaaacaa
    60961 ccgttacgat aggtttaaat ccgaaggacc ccatgctttc agctgcttca agtagagaat
    61021 tgtcaatact gttcattgtt ccagcaacat atagaaatac cagtgggaat agttgcagtg
    61081 taaagacaag tataattcct ttgaatccat aaatatcgat agctggaaga tgaagggcat
    61141 ttgtcaaaaa tttagtgatg acctcatttc gtctcagcaa gagaatccag gagtaggctc
    61201 ctacgaaagg agctgacatg gaagcaatga taatcaatat ttgtagaaat ttcttcccct
    61261 tgaagtcata catagagaag agataagcta atagggttcc tacaactaag gaagtgacag
    61321 tagcggtaat ggaaaccctg aaactgttga ctagtgtctc agagtagtag gttttactaa
    61381 agaaagtgac aaaattagct agtgagaatt atccttcatg tataagtgct tacttgagca
    61441 cggtaacgat aggataaacg agaaagacaa gataggtaag aaagaggaag aaagaggaag
    61501 ctgtccaaat atttagtttt ttacgttcca tggttgactc cttttatcag gttttgggaa
    61561 ccatctgcag aaaagatgtt taatttttgc gtattgattc gtagacgaat acgattgcct
    61621 ttttgtagat cttcttcaaa agttgattct tcactaactt gaatttttga ggcaaaacct
    61681 gtctcaatga aataatccgt atttagtcca agatagacgc tatcgctaat agttccttca
    61741 atatctccag attcatcttt gataaactct tcgggacgaa tgcttacatg aatagcttgc
    61801 tcttcaacct gatcaagagc tggcattcga agggcatagc catctgaaaa gacgatataa
    61861 gcgccgtcgc tccgtttttc aagattggca gggataatat ttgtgcgtcc gataaaggtt
    61921 gccacaaact cattagctgg tttatgatag agtttttttg gtcggccgat ttgttggatc
    61981 accccatctt tcataacagc aatttggtct gaaatagcca tggcttcttc ttggtcgtgg
    62041 gttacataaa cagttgtaat tcccacttcg tgttggattt ctcggatggc ttgacgcgta
    62101 tccaagcgaa gtttggcctc cagattacta agtggctcgt ccatgaggag aacacttgga
    62161 ttaaccgcta agacgcatgc caaggtgaca cgttgttgtt gtccaccact gagtttatcg
    62221 ggctttcgat ccgcatattg agcaatttgc atgagtccaa gatacttgtt ggtctgttga
    62281 atcaattctt cttttggaac cttcttttgc ataagaccaa aagcaacgtt gtctcggaca
    62341 gtcaaatgtg ggaaaatagc gtagttttgg aaaaccagcc cgatattgcg tttgctgggt
    62401 tccatattat tgatttttgt atcatcgaag taaaattctc catctttgat actgttgaaa
    62461 cctgcaatca tacgaagaag ggtcgttttc ccacatcctg aagctccaag aagggtaaag
    62521 agacttcctt ttggaattgt aatgttcaaa ttctcaataa cagggacatc gtggtagatt
    62581 tttttggcgt taataatttc gatctcactc atagtgaacc tcttttactg tttagattgg
    62641 atatctgtaa agacttcgtt gtatttctta acgatatctg atttattctt gatgacataa
    62701 tcataatctt cagtgagtgt tttgattttg tcaattggtt tcatgttttc gcttgtttta
    62761 gcatttttac gaacaggacg gttagtagtg gttgtaccaa gtgtatcttg tacttcttga
    62821 gagataataa aatcgataaa tttcttggca ttttccatat ttttagattt tttaacgata
    62881 gcagcactag caggtaggaa gacggttcct tcttttggat agactacttt aatgttagct
    62941 ccgtcattta agagtttaac tgctggatct tcataagaga gaccaacagt catttctcca
    63001 tcagcgactg ctttatagac accagatgaa cttaaaccga ttttatagta tattgaaact
    63061 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgattaa
    63121 tttgtcctgt tcttatttca ttttactata ccatcaataa gtgtgaaaag atcttttaca
    63181 taagaccaag ccttatcatc tttgtaacca ccttgagctt gtagcatatt tgttaattga
    63241 gcaaaggcgc tagaagagtt tgctgggtca gcagttgcga tttttccttt tagttcaggt
    63301 ttgagaaggt cgctatatcc ttcgatgttc atgcctttag ttaaatcagg gtggacgatt
    63361 aaaacactac catctagtgt ataaggagta gagaagccag ttgtgttttg atattctttg
    63421 ataacattat cattttcttt tgaaatatag ttttcaaaga gttctccgtg ggtagcatat
    63481 tgtgtataag aaccaccaaa gataacatca gctacaggaa cttctttttc tgactctagt
    63541 tttttgaaaa gttctccagt accagcttga atcagttcta ttttgatacc atatttttct
    63601 tcaaaggcag gaatagttgc tccaattaag ccttctgagt ttggtcaata aacgactagc
    63661 gaaccaccgt ctcctttatc agatgaactg tcatcggcag attcattaga agaacaagca
    63721 gcataataca tccatttctt tttcatgatg gatacctccg ttgtgttatt taagtttatt
    63781 ttaaaacaat gtaagcgttt ttaaaaccta caattctatt ctatagtgta ttgaatctat
    63841 aacagtacac tttgactgct aaaatatttc tataaattaa tttgactttc ctgatagaga
    63901 tgttcacatc ttatttcaat tcactatatt agagtaaaat tctctacaaa aagaagaata
    63961 gcctatttta ctattcttcc gagtaatttc aattcctttg gggaaatatg gagatgcttt
    64021 ttaaatactt tggcaaaata tttatagtct gaaaatccaa cttggtcaga gatagcgctt
    64081 aaaggggagt tgggagattc agccatctta tctatagctt gtttcaggcg atattgtaag
    64141 atatattcat ttagagtcat ggggaagtct tctttgataa ccttatatag atgcttgtta
    64201 tctgcaaata gctagagcgt ttcaaggaaa tgaactagaa ataacaatta atatggtggt
    64261 tcagaaatac cttttgataa tcaataagat cttcaggatg aagtgcgttg actccatcca
    64321 tttcatattt ccgatttaat aaacgatatt tgttttcacc aaattgatga aaagggagta
    64381 gttgaacttg gtcgatattt aatgagttaa atagagtagc gaatttttct gcatcctcta
    64441 aactattgtt aaaattagga ataactggga ttcttaaaac gatagtttta ttttgagaaa
    64501 aagcataatg aatgttttta ataatcattt gattaaaaac cccagtcact tttttatgtt
    64561 ttatagaatt ataatgtttt aggtctgtgt agataaaatc cacatattga attaaatcaa
    64621 taaatttttc atgatcaaca aaggcagtag tttcaatggc agtgtgtatg tgatgttctt
    64681 tagctgattt taagatggct ttagcaaatt caaactgagc aaatatttca cctcctgata
    64741 aagttaaacc tccaccggat tcttcgtaaa attctttgtc ttttaatacc tctgtaataa
    64801 tttcttctac agtcttttct tcaccgacta aggtgaattt ctctcgttga gcatctttca
    64861 ttttttcagg tttcattctt tgagattcag gattagaaca ccatggacag cgcagaggac
    64921 atccttttaa aaaaacagtt gtacgaatac ccggaccgtc atgaattgaa aagtgttgaa
    64981 tattaaaaat aattccttta gatatttcca taagagttcc tcctcttcat aagtctatcc
    65041 tatcacaaaa acgaaagaaa aacaattacg aacgaaaggt taatttgttg ttttttgctt
    65101 tttattttgg tagaataaaa cggaggtgta aaatgaaaag attggaacaa attattaaat
    65161 tagtatcaga atatgaaaag atcgacgtta atacattatc ggaaaaatta aatgtatcga
    65221 aagtaacgat tagaaaagat ttagataaat tagagtcaaa aggtttatta cacagagagc
    65281 atggatatgc tgtattaaat agtggagatg acttaaatgt acgtttgtca attaactatg
    65341 aaattaagag aaaaattgtt caggaagcag taaaattggt gtcagataat gaaacaataa
    65401 tgatagaatc tggatcgacc tgtgctttac ttgctgagga aatttgcaag caaaaaagaa
    65461 atgttacgat tgtaacaaat tcatttttta tagcaaattt tgtgagagct tatgattcat
    65521 gtcgtattat tgttcttggt ggagagtttc agaaggattc acaggttact gtgggacctt
    65581 tattaaaaga aatgatacag acttttcatg tgcatcaagc ttttgttggg acagatggtt
    65641 acgataaaga gatgggcttt acaggaaaag atttaatgcg cagtgaggta gttcaatata
    65701 tttcagcagc gtcggataaa gtcattgtac taactgactc aagtaaattt gataaaaggg
    65761 gtacagtaag aagatttgct ttaagtcaag tctatgaagt aataacagac gaaaaacttt
    65821 ctaaacaaaa tatagctaca ttagaaaatg ctgggataat ggttaaggta gtttcgtaag
    65881 aggttaagtg tatgaatcaa gataggaata aactgctttc taaaattgct tatctgtatt
    65941 atattgaaaa cttaaatcag tcacaaatag cagcaaaatt aggaatttat agaacctcta
    66001 ttagtagaat gctaacagaa gcaaggaatg taggaattgt taaaattgaa atagagaatt
    66061 ttgataccaa tatgtttaag ttggaaaatt atgtaaaaga aaaatacagt ttggaaagtt
    66121 tagaaattat tccaaatgaa tttgatgata ctccaacaat tttatctgaa agaatttctc
    66181 aagttgcagc aggcgtcctt aggaatctaa ttgatgataa tatgaaaatt ggcttttctt
    66241 gggggaaaag tttaagtaat ttagtagatt taattcacag taaaagtgtc cgaaatgttc
    66301 acttctatcc tctagcaggt ggtcctagtc acatacacgc taaataccat gtgaatacac
    66361 tgatttatga aatgtctaga aaatttcatg gagagtgtac atttatgaat gcaacgattg
    66421 tgcaagaaaa taaattgtta gcagatggta ttttgcaatc aagatatttt gaaaatttga
    66481 aaaatagttg gaaagattta gatatagctg tagtcggaat tggtgatttt agcaataaag
    66541 ggaaacatca atggttagac atgcttacag aggatgactt taaagaattg accaaagtta
    66601 aaactgtagg agaaatttgt tgtcgatttt ttgattcaaa aggtaaagaa gtctatgaaa
    66661 acttacagga aagaacgata gccatctctt tggaagattt aaaaaatatt cctcaaagtt
    66721 tagctgttgc ttacggtgat acgaaagtat cttcgattct ttctgtcttg cgtgctaatt
    66781 tagtaaatca tttgattaca gataaaaata caattttaaa agttttggaa gaagatggtg
    66841 atttgacttt tagagagatt ctaggtgagt gaaaatgata gactgatcag tttatcgttt
    66901 tttcttttta gtcgattgca catttgtgct tatataaaca aaaatagttt atctgttgtt
    66961 tttggattga caactttatt atgtagttgt attctatagt tacaaaagaa aattttaaaa
    67021 tttcaaatga aaaaagcttt ttacatagtg aaatgaggag gaatttatgg aaattattgt
    67081 tccagatcaa attatcatgg gtttaatttt atatgctggc gatgcgaaac aacatattta
    67141 taaagcatta gattacataa agaacggtac atgtgaacga tgtgaagaag aaatccagtt
    67201 agctgatgcc gccttattag aagctcataa tctacaaaca aaattcttgg cacaggaagc
    67261 gtctggtaca aagacagaaa ttacagctct ctttgttcat tcacaagatc atctcatgac
    67321 tagtatgacg gagattaatt taatcaaaga aattattagt ttgagaaaag aacttcataa
    67381 aaaataatac tagagtatta tcattgttat taacatagag gaggaaaaca taatggtgaa
    67441 gattggtttg ttttgtgcag caggtttttc tactggtatg cttgtaaata atatgaaaat
    67501 tgcagcgcaa gctagtggag ttgaggcaga aatagaggcg ttttctcagt ctaaattagc
    67561 ggattatgcg ccaaatatag atgttgcact attgggtcca caagttgctt atacattaga
    67621 taaatcaaaa gaaatttgtg ataagtgtga tgttccgata gctgttattc cgatgatgga
    67681 ctatggtatg ttagatggga aaaaagtatt agatttggcc ctatctttga ttagtgggta
    67741 agaaaaggag atttattatg tcaaagatgg atgttcagaa aatcattgca ccgatgatga
    67801 agtttgtgaa tatgcgtggc attatagctc taaaagatgg gatgttagca attttgccat
    67861 tgacagtagt tggcagtttg ttcttgatta tgggacaatt gccgttcgaa ggattaaata
    67921 agagcattgc tagtgttttt ggagctaatt ggacagagcc gtttatgcaa gtatattcag
    67981 gaacttttgc tattatgggt ctaatttctt gtttttcaat tgcctattct tatgctaaga
    68041 atagcggagt agaggcttta ccagctggag ttctatctgt atctgcattc tttattttgc
    68101 taagatcatc ttatatccct aaacaaggtg aggcgattgg ggacgctatt agtaaagttt
    68161 ggtttggagg ccaaggaatt atcggtgcta tcattatagg tttggtagta ggaagtattt
    68221 ataccttctt tataaagaga aaaattgtta ttaagatgcc agaacaagtt ccacaagcta
    68281 ttgccaaaca gtttgaagca atgattccag catttgtaat tttcttatct tctatgattg
    68341 tatatatttt agcgaagtca atgactaatg gcggaacatt catagaaatg atttattctg
    68401 ctattcaagt tccgttgcaa ggtttaactg gatctttgta tggtgctatt ggaattgcat
    68461 tctttatatc atttttgtgg tggtttggtg ttcatgggca atcggtagta aatggagtag
    68521 tgacagctct gcttttatct aatcttgatg ctaataaagc tatgttagcc tctggtaatc
    68581 tatcattaga aaatggagca catattgtta ctcaacagtt tttagattca tttttaattc
    68641 tatcaggttc agggattacg tttggtcttg tagttgccat gctttttgta gcaaaatcaa
    68701 aacaatacca agccttagga aaagttgcag cttttccagc aatatttaac gtaaatgagc
    68761 cagttgtatt tggatttccg attgtcatga atccagttat gtttgtacct ttcattcttg
    68821 ttcctgtact tgcagctgtg atagtatatg gagctattgc aacaggtttc atgcagccat
    68881 tctcaggggt aacattgcct tggagtacac cagctattct atcaggattt ttggtgggtg
    68941 gatggcaagg tgttgtgact cagttattag tattggcgat gtctacaatg gtttactttc
    69001 cattctttaa gatacaggat cgtttagctt accaaaatga aatcaaacaa tcttagaggt
    69061 atttgtgtgt tactgttaaa ctcacacatt tgtgctaaaa attagagagt taaaattttt
    69121 ctagttaaaa gcttgaaaat ttctataaaa atcggtatta tattttcgaa agaaataaaa
    69181 atattttcga aagaaaggtg cttacgatgg taaatacaga agtagcaaga acaacaatca
    69241 agacagaata ttttggcagc cttactgaaa ggatgaacaa atatcgagaa gatgttttaa
    69301 ataaaaaacc ttatattgat gctgagagag cagttctagc aacacgcgcc tatgaacgat
    69361 acaaggaaca acctaatgtc ctaaaacgtg catatatgct gaaagaaatt ttggaaaata
    69421 tgactatcta tattgaagaa gaatctatga ttgcgggaaa tcaagcttct tccaataaag
    69481 atgctcctat ttttccggaa tatacgctag aatttgttct caatgagttg gatctttttg
    69541 aaaagcgtga tggagatgtt ttctatatta cagaagaaac aaaagaacaa cttagaagta
    69601 ttgctccgtt ttgggaaaat aataatttac gtgctagagc tggtgcctta ttacctgaag
    69661 aagtgtctgt ttatatggaa acaggattct tcggtatgga aggtaagatg aattctggag
    69721 atgctcactt agcagttaac tatcagaaac tgttgcaatt tggtttaaga ggttttgaag
    69781 agcgggctcg taaagcaaaa gtagctctag atttaacaga tccagcaagt attgataaat
    69841 atcattttta cgactctata tttatcgtaa tcgatgctat taaagtatat gcaaagcgct
    69901 ttgttgctct tgctaaaagt ttagccgaaa atgcaaatcc taaacgtaag aaagaattac
    69961 ttgagattgc agatatttgc tctagagtcc catatgaacc ggcaactact tttgcagaag
    70021 ctattcaatc agtttggttt attcaatgta ttttacaaat tgaatctaat ggccactctc
    70081 tttcatatgg ccgttttgat caatatatgt atccatatat gaaggctgat ttagaaagtg
    70141 gtaaagaaac agaagatagc attgttgaac gtctgacaaa tctttggatt aagacaatta
    70201 caattaataa ggttcgcagt caatcacata cattttcttc agcaggaagt cctttatatc
    70261 aaaatgttac aattggtgga cagactcgag ataagaagga tgctgttaac ccattatctt
    70321 atttggtatt aaaatcagtt gcacaaaccc atctaccgca acctaatcta actgtacgtt
    70381 accatgcagg tttagatgct cgtttcatga atgagtgtat tgaagtgatg aaacttggtt
    70441 ttggtatgcc tgcatttaat aatgatgaga ttattattcc ttcttttatt gcaaaaggag
    70501 tattggaaga tgatgcttat gattacagtg ccattggatg tgttgaaacg gcagttccag
    70561 ggaaatgggg ctatcgttgc acaggtatga gttatatgaa cttccctaag gttctactta
    70621 tcacgatgaa tgatggaatt gatccggctt cgggtaaacg gtttgcacca agctttggtc
    70681 attttaagga tatgaagaac ttttctgaat tagaaaatgc ttgggataaa acactaagat
    70741 atttgacacg aatgagtgtt attgttgaaa attctattga tttatcattg gaacgagaag
    70801 ttcctgatat tctatgttca gcattgactg atgattgtat tggtcgtgga aaacacctta
    70861 aagaaggtgg agcagtatat gattatatat caggattgca agttggaatt gcaaatttgt
    70921 cggattcatt agctgcaatt aaaaaattgg tgtttgagga agaacgtata agcccaagtc
    70981 agctttggca tgcattggaa acagattatg ccggagaaga aggtaaggtc attcaagaaa
    71041 tgttgattca tgatgcacct aagtatggta atgatgatga ttatgctgac aaattggtta
    71101 ctgctgctta tgacatttat gttgatgaaa ttgctaaata tcctaataca cgttatggaa
    71161 gagggcctat tggaggaatt cgttattcag gaacatcttc tatatcagcc aacgtagggc
    71221 agggacgtgg aacattagca actccagatg gacgcaacgc gggtacaccg ttagcagagg
    71281 gttgttcacc atcacataat atggatcaac acggccctac atctgtttta aaatctgttt
    71341 caaaattacc aacagatgaa atcgtaggtg gggttctctt aaatcagaaa gtaaatcctc
    71401 aaacgttagc caaagaagaa gataaattaa aactaattgc tttgttacga acattcttta
    71461 atcgtttaca tgggtaccat attcaataca atgttgtttc cagagagacg ttgattgacg
    71521 ctcagaaaca tcctgaaaaa cacagagact taattgttcg tgttgcagga tactctgcat
    71581 tcttcaatgt tctttctaag gcaacccaag atgacattat aggacgtact gagcatactt
    71641 tgtaaaataa agaggttctt tttatggaat ttatgcttga cacattaaat ttagatgaga
    71701 ttaaaaagtg gtctgaaatt ttgccgctag ctggggtaac ttcaaatccc actattgcaa
    71761 aaagagaggg ttctattaat ttttttgaac gaatcaaaga tgtaagagaa ttgattggct
    71821 ctacaccctc tattcatgtt caggtgattt ctcaagattt tgaaggcatc ttaaaggatg
    71881 ctcatgaaat tcgaagacaa gcaggagatg atatatttat caaagtacct gttactccag
    71941 ctggattacg tgcaataaag gtgctaaaaa aagagggcta ccatatcact gcaacagcta
    72001 tttatacagt tattcaggga ttattagcta tcgaagtagg agcggattac ctagctccat
    72061 attataatag aatggaaaat ctgaacattg attcaaattc tgtcattcgt caattagctc
    72121 ttgctattga tagacagaac tctcctagta agattttagc tgcatccttt aaaaatgtag
    72181 cacaagtaaa taatgcttta gctgcaggtg cgcatgctgt tacagcagga gcagatgttt
    72241 ttgaatcagc tttcgccatg ccatctatcc aaaaggcggt tgatgatttt tctgacgatt
    72301 ggtttgttac tcaaaatagt cgttccattt agatagagag gaaatacata tgagaatttt
    72361 tgctagtcct tctagatata ttcaggggga aaatgccttg tttgaaaatg ccaaatcaat
    72421 tttggatttg ggaaattacc cgattctatt atgcgatcag ttggtttatg atattgttgg
    72481 aaaacgattt gaagattatc tacataggta tggtttccat attgttctgg cgctatttaa
    72541 tggtgaagct tctgacaatg aaatcaatcg agttgttgcc ttggctgaga aagaaaattg
    72601 tgatagtatt atcggtcttg gtgggggaaa gacgattgat agcgcaaaag ctattgcaga
    72661 tttgattgaa aagcctgtta ttattgctcc aacaattgca tcgaccgacg cacctgtatc
    72721 tgctttatct gttatttata cagatgaagg tgcatttgat cattatctat tttattctaa
    72781 aaatccagat ttagttttgg ttgatacaaa agttatttca caagccccta agcgtttatt
    72841 agcgtctggt attgcagatg gtttagcaac ttgggttgag gcgcgtgcgg ttatgcaggc
    72901 aaatggaaaa actatgttgg gacaacagca aacattggct ggagttgcaa ttgcgaagaa
    72961 atgtgaagaa acgctgtttg cagatggttt acaggctatg gcagcttgtg aagctaaagt
    73021 ggtgacacca gcattagaaa atattgttga agctaatact ttattgagtg gtctaggttt
    73081 tgaaagtgga ggattagctg cggcgcatgc aattcataat ggttttactg cattgacagg
    73141 tgacattcat catttaacac atggtgaaaa agtagcttat ggaactttag tacaactatt
    73201 attggaaaat agacctaaag aagaacttga taagtatatt gagttttaca aaaaaattgg
    73261 tatgccaaca actctaaaag aaatgcattt ggatcaagtt ggatatgatg atttaataaa
    73321 agttggtaaa caagcaacta tggagggtga gacaattcat cagatgccgt ttaagatttc
    73381 gccttcagat gttgctcaag ctattatcgc tgtagatgcc tatgtaaatt caaaataaac
    73441 aataaggact actgttttcc aaatggtagt cttttattga tccctgtatt gaattctata
    73501 gaagattgaa ataggatgag aacaaatcga ttgggaaagt aaaattaatt tctataaatg
    73561 ttttagcaat tgtttcgtac tatttcagat tcagtctact atacgttctt cataaatcaa
    73621 aaagcgacat aggtagtcgg ctatttattg tgaatacatt aattagcatt ccagttttat
    73681 cttcggtcta aaataagtat tttgtgctat acgagataag cttcttgact tactccttga
    73741 tttactgcat aacaatggga taaaaagtgg gagatagagc aattcatagt catcaaaatt
    73801 aatgagatac agtatacagt ttttccttta aacacatttc aaattccctc aaaaatggta
    73861 taatagtaac atcacaaaat tggagagaga ccatgagttt ttacaatcat aaagaaattg
    73921 agcctaagtg gcagggctac tgggcagaac atcatacatt taagacagga acagatgcat
    73981 caaaacctaa gttttatgcg cttgatatgt tcccttatcc gtctggagct ggtctgcacg
    74041 taggacaccc agaaggttat actgcaaccg atatcctcag tcgttacaaa cgtgcgcaag
    74101 gctacaatgt ccttcaccca atgggttggg atgcttttgg tttgcctgca gagcaatacg
    74161 ctatggatac tggtaatgac ccagcagaat ttacagcgga aaacattgcc aacttcaaac
    74221 gtcagatcaa tgcgcttgga ttttcttatg actgggatcg tgaagtcaac acaacagatc
    74281 caaactacta caagtggact caatggattt tcaccaagct ttacgaaaaa ggcttggcct
    74341 atgaagctga agtgccagta aactgggttg aggaattggg aactgccatt gccaatgaag
    74401 aagtgcttcc tgacggaact tctgagcgtg gaggctatcc agttgtccgc aaaccaatgc
    74461 gccaatggat gctcaaaatc acggcttacg cagagcgctt actcaatgac ttagatgaac
    74521 ttgattggcc agagtctatc aaggacatgc aacgcaactg gattggtaaa tcaactggtg
    74581 ctaatgtaac ctttaaagtt aagggaacgg acaaggaatt cacagtcttt accactcgtc
    74641 ctgatactct tttcggtgcg actttcactg tcttggctcc tgaacatgaa ttagtagacg
    74701 ctatcacaag ttcagagcaa gcagaggctg tagcaaacta taaacatcaa gctagcctca
    74761 aatctgactt ggctcgtaca gaccttgcca aagaaaaaac tggtgtttgg actggtgctt
    74821 atgccatcaa ccctgtcaat ggtaaggaaa ttccaatctg gattgccgac tatgttcttg
    74881 ctagttacgg aacaggtgcc gttatggccg ttccagctca cgaccaacgt gactgggaat
    74941 ttgccaaaca atttgacctt ccaatcgtcg aagtgcttga aggtggaaat gtagcagaag
    75001 ctgcctatac agaggatggt cttcatgtca attcagactt cctagatgga ctcaacaaag
    75061 aagaagctat tgccaagatt gtggcttggt tggaagaaaa aggctgtgga caagagaagg
    75121 ttacctaccg tctccgcgac tggctcttta gccgtcaacg ttactggggt gaaccaattc
    75181 ctatcattca ttgggaagat gggacttcaa cagctgttcc tgaaagtgaa ttgccacttg
    75241 tcttgcctgt aaccaaggat atccgccctt caggtacagg ggaaagtcca ttggctaact
    75301 tgacagattg gcttgaagtg actcgtgcag atggtgtcaa aggtcgtcgt gaaaccaaca
    75361 ctatgccaca atgggcaggt tcaagctggt actacctccg ctatattgac ccgcacaata
    75421 ctgagaaatt ggctgatgag gacctcctca aacaatggtt gccagtagat atctacgtgg
    75481 gtggtgcgga acatgctgta cttcacttgc tttatgctcg tttctggcat aaattcctct
    75541 atgacctcgg tgttgttccg actaaggaac cattccaaaa actctttaac caagggatga
    75601 ttttgggaac aagctaccgt gaccaccgtg gtgctcttgt gacaaccgac aaggttgaaa
    75661 aacgtgatgg ttccttcttc catgtagaaa caggggaaga gttggagcaa gcgccagcca
    75721 agatgtctaa atcgctcaag aacgttgtta acccagacga tgtggtggaa caatacggtg
    75781 ccgataccct tcgtgtttat gaaatgttta tgggaccact cgatgcttcg attgcttggt
    75841 cagaagaagg tttggaagga agccgtaagt tccttgaccg agtttaccgt ttgattacaa
    75901 gtaaagaaat ccttgcggaa aacaatggtg ctcttgacaa ggcttacaac gaaacagtca
    75961 aagctgttac tgagcaaatt gagtctctca aattcaacac agctattgcc caacttatgg
    76021 tctttgtcaa tgctgctaac aaggaagata agctttatgt tgactatgcc aaaggcttta
    76081 ttcaattgat tgcaccattt gcacctcact tggcagaaga actctggcaa acagtcgcag
    76141 aaacaggtga gtcaatctct tatgtagctt ggccaacttg ggacgaaagt aaactggttg
    76201 aagacgaaat cgaaatcgtt gtccaaatca aaggtaaagt ccgtgccaaa ctcatggtcg
    76261 ctaaagacct atcacgtgaa gaattgcaag aaattgctct agcggatgaa aaagtcaaag
    76321 cagaaattga cggtaaggaa atcgtgaaag tgattagtgt accaaataaa ttggttaata
    76381 ttgttgtaaa ataaccaatt tatttgctga tttccaacct caaacagttt cccaaactgt
    76441 ttgagccaac taaactcgtt aatatcgttg tgaaataagg taggaatcct tcagagtaga
    76501 atctggagga ttttttgaat cttcttatga aagtatggta tactatgggc aactataaag
    76561 tttgaaaagt gaaaaaagga gaaagctatg ccagtaaatg aatatggtca aatgattggg
    76621 gagtcaatgg aaggttatac accaggtgaa ctgccttcta ttgatttctt agaagggcgt
    76681 tatgctagga tagaggctct ttcagtggaa aagcatgcgg aggatttgct agctgtttat
    76741 gggcctgata cgcctcagga gatgtggacc tacctttttc aggagccagt agcagatatg
    76801 ggggagctgg ttagcctttt acatcagatg ttggctcgta aggaccgttt ttactatgca
    76861 atcatagaca aggcgactgg taaggctttg ggatcttttt ctctcatgcg cattgaccag
    76921 aataaccgag taatagaagt cggagcagtc actttttctc cagagctaag gggtacacgg
    76981 ataggaactg aagctcagta tctcctagct cgctatgttt ttgaggagct aaactatcgt
    77041 cgctacgagt ggaaatgcga tgccttaaat ctgccatcca gacgagctgc ggagcgtttg
    77101 agctttattt atgaaggaac cttccgtcag gcagtggttt ataagggacg tacgagagat
    77161 acggattggt tgtctatgat tgataaggac tggcctcaag tcaaagatcg tttggaaaca
    77221 tggttgcgtc ctgaaaattt tgataaaaat ggacagcagt acaagagctt gagagaactt
    77281 taagaggtgt tgagatgatt actattaaaa agcaagaaat tgtcaagcta gaggatgttt
    77341 tgcatctcta tcaggctgtc ggttggacaa actataccca tcaaacagag atgctggagc
    77401 aggccttatc tcattcatta gtaatttatc tggcacttga tggtgatgct gtggtgggct
    77461 tgattcgttt ggttggagat ggtttttcat cagtttttgt acaggatttg attgttttgt
    77521 ctagctatca gcgccaaggg attggtagct ccttgatgaa acaggcttta ggaaatttta
    77581 aagaggccta tcaagtccag ctggcgacag aacagacaga aaaaaacgtg ggatttaatc
    77641 gttctatggg ctttgaaatt ttatccacct ataattggat agggatgact tggatgaatc
    77701 gtaaaaaata acaaaacttg ttttttctta agcaaaattt aaggatggtc tagtattata
    77761 taatcattaa ataaagacct cctaacttta tttaataaaa tcctaaactt ttttcatcac
    77821 aatctcctaa tgaagccacc caatcaggtg gcttttttgc gtggtgaggt gctggtgata
    77881 gaaatttttt gcaaaatggt aaaattttag aaaagttaag ctagttttaa gtttcgtctt
    77941 gtatcatgta gttattaaat aaagacctcc taactttatt taataaaatc ctaaactttt
    78001 ctttttcata ataatctccc ttaactccac ccaatcaggt ggagtttttt agctctattt
    78061 caggcttttg gggactattc taaaaataat ttttcgatat ttttcggtat ttttcggatt
    78121 ttggtcgggg aattggcggg gactttttta gcgaatatga ctaagaaata ggtctgtggt
    78181 cgcttcagct agttcaaact caatttgatt gtaagtgact gttaattgaa ggactggaac
    78241 tactgtaata atgattttgc ttgtctagta gtggcgtatt aaatgagaag tgacatgtaa
    78301 gattgtctct tcgtttacga aatcaaaatt tctatgaaat tgatagaatc cctaacgttc
    78361 tcttaatctt aaccgtcttg tcgtacagcg gttgaagaaa atgtaaacct ttgacaaaat
    78421 tcgtgaacta tgggataata aaaaggaatt gagtactagt tctatatcat aggctagaaa
    78481 agaccccaag ctcacgacca aataagcttg aggtcttttt tgacactatt tgtccttgtt
    78541 tagccattta tcgactatac gaagaacgac accgaccaca attggtccga tgatagtttt
    78601 gagtactaat tccatcatgg gctatctcac ctcctttcgt aggcggtgta gaagtgccgt
    78661 ataatattat accacataag tgctaaactt aggagtcacc caatcaggtg gcttttttgt
    78721 ttgtggcttg tttttttgat ataatagagc catgagtaga attttagata atgagatgat
    78781 gggtgatgag gagttagtag aacgcacgct ccgtcctcag tatttacgtg aatatattgg
    78841 tcaggataag gttaaggatc agcttcagat ctttatcgaa gccgctaaaa tgcgggatga
    78901 agcgctggat catgtgctct tatttggccc tccaggtttg gggaaaacaa ccatggcttt
    78961 tgtcattgcc aatgaactgg gagtcaatct caagcaaacg tctggtcctg ttatcgaaaa
    79021 agcgggtgat ttggtagcga ttttgaatga gttagagcct ggagatgtcc tctttattga
    79081 cgagattcat cgcttaccca tgtcagtgga agaagtgctt tatagtgcca tggaggactt
    79141 ctacatcgat attatgattg gggctggtga aggcagtcgc agtgttcatt tggagttgcc
    79201 tccttttacc ttgattggtg cgacgactcg ggctggtatg ctctcaaatc cactacgggc
    79261 acgttttggg attacaggtc atatggagta ttatgcccat gctgacttga cagaaattgt
    79321 cgagcggacg gcagatattt ttgagatgga aatcactcat gaggcagcat ctgagttggc
    79381 cctacgtagt cgtggaaccc ctcgtattgc caatcgtctc ctcaagcgcg tgcgcgattt
    79441 tgcccagata atggggaatg gggtaatcga tgatattatt accgataagg ctttgactat
    79501 gctggatgtt gaccatgaag gtttggacta tgtggatcaa aaaatccttc gtaccatgat
    79561 tgagatgtac agtggaggac ctgttggtct aggaactctt tctgtcaata tcgccgaaga
    79621 gcgtgagaca gttgaagaca tgtatgagcc ttacttgatt caaaaaggtt ttatcatgcg
    79681 gacacggtct ggacgggtgg cgactgctaa ggcatatgag cacttaggtt atgaatacag
    79741 tgaaaaataa gcaagaaatc ttagaggctt ttagagaaaa tccagatatg atggccattc
    79801 tgacgatcat ccgagacctt ggtttgaaag actcgtagtt ggcagcaggt tctgtcagaa
    79861 atttcatctg gaatcttttg tcagacaaat ccccttttga tcatgaaaca gatatagatg
    79921 tgattttctt tgatccagat ttttcttatg aggaaacctt attactggag aaaaagctga
    79981 gagaggattt tcctcagtac cagtgggaat tgaaaaatca ggtctatatg catcagcaca
    80041 gtcctcacac tgcttcctat accagttctc gtgatgctat gagtaagtat ccagaacggt
    80101 gtacggcagt tggactgcgc ttgaatgaag aatcagattt tgaactctat gcaccttatg
    80161 gtttggagga tattttgaat tttcaagttc gtccaactcc tcatttctta gaaaatgaag
    80221 accgaatgga actctatcaa acacgtttat ccaagaaaaa ttggcaggag aaatggaaaa
    80281 atttgatttt taaaaatact taaggaaact ttaagctagg gagtgtacac taagttcata
    80341 agttaagaag accttaactt aaactcctaa aactttttca taataatctc cctataaaaa
    80401 taaagtcgcc caatcaggcg gcttattttt ttgaaaaatg ggcatggtgc ctgagaataa
    80461 atagcttagt gatagaagaa aatggggaaa tatggtataa tgaaacgata gatttttgaa
    80521 taggaataag atcatgtttg gattttttaa gaaagataag gctgtggaag tagaggttcc
    80581 gacacaggtt cctgctcata tcggcatcat catggatggc aatggccgtt gggctaaaaa
    80641 acgtatgcaa ccgcgagttt ttggacataa ggcgggcatg gaagcattgc aaaccgtgac
    80701 caaggcagcc aacaaactgg gcgtcaaggt tattacggtc tatgcttttt ctacggaaaa
    80761 ctggacccgt ccagatcagg aagtcaagtt tatcatgaac ttgccagtag agttttatga
    80821 taattatgtc ccggaactac atgcgaataa tgttaagatt caaatgattg gggagacaga
    80881 ccgcctgcct aagcaaacct ttgaagcttt aaccaaggct gaggaattga ctaagaacaa
    80941 cacaggattg attcttaatt ttgctcttaa ctatggtgga cgtgctgaga ttacacaggc
    81001 gcttaagttg atttcccagg atgttttaga tgccaaaatc aacccaggtg acatcacaga
    81061 ggaattgatt ggtaactatc tctttactca gcatttgcct aaggacttac gagacccaga
    81121 cttgattatc cgtactagtg gagaattacg tttgagcaat ttccttccat ggcagggagc
    81181 ctatagtgag ctttatttta cggacacctt atggcctgat tttgacgaag cggccttgca
    81241 ggaagctatt cttgcctata atcgtcgtca tcgccgattt ggaggagttt aggaggaaat
    81301 atgacccagg atttacagaa aagaaccttg tttgcaggga ttgccctggc tattttccta
    81361 ccaattttaa tgattggggg cctcttgctt cagatagcaa tcggaatcat agccatgcta
    81421 gccatgcatg aacttttgaa gatgagaggt ctagagacca tgacgatgga gggcctcttg
    81481 accctctttg caacctttgc attgaccatt cccttggaga attacctgac ttttttgcca
    81541 gttgatggga atgtggttgc ctatagtgtt ttgatttcaa tcatgttagg aacgaccgtt
    81601 tttagcaagt cttatacgat tgaggatgcg gttttccctc ttgctatgag cttctacgtg
    81661 ggctttggat ttaatgcttt actagatgct cgtgttgcag gtttggacaa ggctctctta
    81721 gccttgtgta tcgtctgggc gacagacagt ggtgcctatc ttgttgggat gaactatggg
    81781 aaacgaaagt tagcaccaag ggtatcgcct aataaaaccc ttgagggtgc cttgggtggt
    81841 attttaggag caattttagt aaccattatc tttatgatag ttgacagtac agttgctctt
    81901 ccatatggaa tttacaagat gtcagtcttt gctattttct ttagcattgc tggacaattt
    81961 ggtgatttac tagaaagttc gatcaaacgt cattttggtg ttaaggattc tgggaaattt
    82021 atccctggac atggtggtgt tttggatcgt ttcgatagta tgttgcttgt atttccaatc
    82081 atgcacttat ttggactctt ttaatcaaaa gacggaggaa acgctatgct cggaatttta
    82141 acctttattc tggttttcgg gattattgta gtggtgcacg agttcgggca cttctacttt
    82201 gccaagaaat cagggatttt agtacgtgaa tttgccatcg gtatgggacc taaaattttt
    82261 gctcacattg gcaaggatgg aacggcctat accattcgaa ttttgcctct gggtggctat
    82321 gtccgcatgg ccggttgggg tgatgataca actgaaatca agacaggaac gcctgttagt
    82381 ttgacacttg ctgatgatgg taaggttaaa cgcatcaatc tctcaggtaa aaaattggat
    82441 caaacagccc tccctatgca ggtgacccag tttgattttg aagacaagct ctttatcaaa
    82501 ggattggttc tggaagaaga aaaaacattt gcagtggatc acgatgcaac ggttgtggaa
    82561 gcagatggta ctgaggttcg gattgcacct ttagatgttc aatatcaaaa tgcgactatc
    82621 tggggcaaac tgattaccaa ttttgcaggt cctatgaaca attttatctt aggtgtcgtt
    82681 gttttttggg ttttaatctt tatgcagggt ggtgtcagag atgttgatac caatcagttc
    82741 catatcatgc cccaaggtgc cttggccaag gtaggagtac cagaaacggc acaaattacc
    82801 aagattggct cacatgaggt tagcaactgg gaaagcttga tccaagctgt ggaaacagaa
    82861 accaaagata agacggcacc gactttggat gtgactattt ctgaaaaggg gagtgacaaa
    82921 caagtcactg ttacacccga agatagtcaa ggtcgttacc ttctaggtgt tcaaccgggg
    82981 gttaagtcag attttctatc catgtttgta ggtggtttta caactgctgc tgactcagct
    83041 ctccgaattc tctcagctct gaaaaatctg attttccaac cggatttgaa caagttgggt
    83101 ggacctgttg ctatctttaa ggcaagtagt gatgctgcta aaaatggaat tgaaaatatc
    83161 ttgtacttct tggcaatgat ttccatcaat attgggattt ttaatcttat tccgattcca
    83221 gccttggatg gtggtaagat tgtgctcaat atcctagaag ccatccgccg caaaccattg
    83281 aaacaagaaa ttgaaaccta tgtcaccttg gccggagtgg tcatcatggt tgtcttgatg
    83341 attgctgtga cttggaatga cattatgcga ctctttttta gataatcgag gaatattatg
    83401 aaacaaagta aaatgcctat cccaacgctt cgcgaaatgc caagcgatgc tcaagttatc
    83461 agccatgctc ttatgttgcg tgctggttat gttcgccaag tttcagcagg tgtttattct
    83521 tatctaccac ttgccaaccg tgtgattgaa aaagctaaaa acatcatgcg ccaagaattc
    83581 gaaaagattg gtgctgttga gatgttggct ccagcccttc ttagtgcaga attgtggcgt
    83641 gaatcaggtc gttacgaaac ctatggtgaa gacctttaca aactgaaaaa ccgtgaaaaa
    83701 tcagacttta tcttaggtcc aactcacgaa gaaaccttta cagctattgt ccgtgattct
    83761 gttaaatctt acaagcaatt gccactcaac ctttatcaaa ttcagcccaa gtatcgtgat
    83821 gaaaaacgcc cacgtaatgg acttcttcgt acacgtgagt ttatcatgaa ggatgcttat
    83881 agtttccacg ctaactatga tagtttggat agtgtttatg atgagtacaa agcagcctat
    83941 gagcgtattt tcactcgtag tggtttagac ttcaaggcta ttattggtga cggtggagcc
    84001 atgggtggta aggatagcca agaatttatg gccattacat ctgctcgtac agaccttgac
    84061 cgctgggttg tcttggacaa gtcagttgcc tcatttgacg aaattcctgc agaagtgcaa
    84121 gaagaaatca aggcagaatt gctcaaatgg atagtctctg gtgaagatac cattgcttac
    84181 tcaagtgagt ctagctatgc agctaactta gaaatggcaa caaacgagta caaaccaagc
    84241 aaccgtgttg tcgctgaaga agaagttact cgtgttgcaa cgccagatgt taaatcaatt
    84301 gatgaagttg cagccttcct caatgttcca gaagaacaaa cgattaaaac cctcttctac
    84361 attgcagatg gcgagcttgt tgcagccctt ctagttggaa gtgaccaact caacgaagtc
    84421 aagttgaaaa atcacttggg agcagatttc tttgacgttg ctagcgaaga agaagtggcg
    84481 aatgttgttc aagcaggatt tggttcactt ggaccagttg gtttgccaga gaatattaaa
    84541 attattgcag atcgtaaggt gcaagatgtt cgcaatgcag ttgtcggtgc taacgaagat
    84601 ggctaccact tgactggtgt gaacccaggc cgtgatttta ctgcagaata tgtggatatc
    84661 cgtgaagttc gtgagggtga aatttcccca gatggacaag gtgtccttaa ctttgcgcgt
    84721 ggtattgaga tcggtcatat tttcaaactc ggaactcgct attcagcaag catgggagca
    84781 gatgtcttgg atgaaaatgg tcgtgctgtg ccaatcatca tgggatgtta cggtatcggt
    84841 gtcagccgtc ttctttcagc agtgatggag caacacgctc gcctctttgt taacaaaacg
    84901 ccaaaaggtg aataccgtta cgcttgggga atcaatttcc ctaaagaatt ggcaccattt
    84961 gatgtgcatt tgattactgt taatgtcaag gatgaagaag cgcaagcctt gacagaaaaa
    85021 cttgaagcaa gcttgatggg agctggttat gaagtcttga cagatgaccg taacgaacgt
    85081 gtcggtgtta aatttagcga tagtgacttg attggtcttc caatccgtat cactgttggt
    85141 aaaaaagcgg ccgatggcat tgtagaagtt aagatcaagg caactggtga caccattgag
    85201 gttcatgcag ataacgtgct tgaaacgctt gaaatcctaa gcaagaaata aaaactataa
    85261 tcagaagaaa aacaaggaaa aaatgtaact agtttttacc ttgttttttc tgtataatgg
    85321 gagaaatgag tagataaaga ggtaaatgta tgctaagatt tccaaaggat tttgtctggg
    85381 gatcctctac ttctggaccg cagacagaag gacgtgtagc tggtgacggt aagggagaca
    85441 atctctggga ttactggttc caagtggagc caaatcgtta ctataatggg attggttcag
    85501 ataagacatc gactttttat gaaaattggg agcgggatat tgagcttttg ttagagactg
    85561 gtcacacagc ctttcggact tctattcagt ggtcacggat ttttccacaa ggctgtggaa
    85621 aagtcaaccc tcaaggtgtg gatttttatc gtaaggtctt tgaggctatt aaggctaaag
    85681 gaattcgtct gttagtcaat ctctatcatt ttgatttacc ttttgccctt caagaggatg
    85741 gtgatggttg ggaaaataag gcgacagtct cagcctatga agactatgct cgtttttgtt
    85801 ttgagactta tggagattta gtggatcaat ggattacctt taacgagccc atcgttcctg
    85861 tagaatttgg ttatttttat gatgcccatt atccacataa ggtggatgca gaggcagctg
    85921 ttaaggtagc ctatcataca caattggcca gcagccgggc tgttaaggct tgccatgaac
    85981 ttttgcctga ttccaagatt gggattgtcc tcaacttgac accggcttat ccacgtagcc
    86041 agcatcctgc tgatgtcaag gcagctcgta ttgcggccct ttttcaggcc caatctttct
    86101 tagatccatc tgtcttgggg acttatccac aggagttggt agaaatcttg catgaacacg
    86161 gtcttttacc tgatgctaca gaggaagagt tggaactcat tcgtgataat acggtggact
    86221 tccttggtgt gaactactat caacctttgc gtgttatggc tcctcgattt gctaagcatc
    86281 cagagagtcc actcttacca gaacattttt acgagcctta tgtgatgcct ggacgtaaaa
    86341 tcaattctca tcgtggttgg gagatttatg agcaagggat ttatgacatc gcccaaaata
    86401 tcaaggaaaa ttatggcaat attgaatgga tgttgactga gaatggtatg ggtgttgaag
    86461 gggaagaaaa attccgtcaa gatggaatga ttcaagatga ttaccgtatt gactttgtaa
    86521 aaggtcatct tcgtgaactt caccgtgcca ttgaagatgg tgccaactgt aagggctact
    86581 tgatttggac ctttattgac tgctggtcat ggctcaacag ctataaaaat cgctatggtt
    86641 tggtcgaatt agacttggaa acgcaagaac gtcgtctgaa gaaatcaggc cactggttca
    86701 aaaaattaag cgataataat ggattttaaa aaggactctg actgattatc ccaatcggtc
    86761 agagtttttt gcttacagga gcttaatttg aactatacca atttttactc ttgacaagtg
    86821 aaagaaacaa gtatatactg tttttgctga ttctataaaa gatgaattag actataccaa
    86881 ttttaaggag aaagcacagc ttacctgtgt cgtatatact atgtgtggaa ttgttggtgt
    86941 tgttggaaac acaaatgcaa ctgatatttt gattcaaggg cttgaaaagc ttgaataccg
    87001 tggctatgat tctgcgggaa tttttgtcct agatggtgct gataaccatt tggtgaaggc
    87061 tgttggtcgt attgcagaat tgtctgccaa gacagctggt gttgagggaa caactggtat
    87121 cggacatact cgttgggcta ctcacggaaa accaactgag gacaatgctc acccacaccg
    87181 ctctgagaca gaacgttttg tcttggtgca taatggggtg attgagaact accttgaaat
    87241 caaggaagaa taccttgcag gtcaccactt caaggggcag acagatactg aaatagccgt
    87301 tcatttgatt ggaaaatttg cggaagaaga agggctctca gttcttgaag ccttcaaaaa
    87361 agcccttcac atcatccgtg gttcttatgc ctttgccttg gttgactcac aagatcttga
    87421 agtcatctat gtagctaaaa ataaatcacc acttttgatt ggtcttggag aaggctataa
    87481 catggtctgc tcagacgcca tggctatgat tcgtgaaact aaccaataca tggaaatcca
    87541 tgaccaagag ttggtaatcg tcaaggctga tagtgtggaa gttcaagact atgatggaaa
    87601 tcgtcgtgag cgtgctagct acactgctga acttgacttg tcagatatcg gtaagggaac
    87661 ttacccttac tacatgctta aggaaattga cgagcaacca actgttatgc ggaaactcat
    87721 ccaagcctac acagatgagg ctggtcaagt tgtcgtagac ccagatatca ttaaggctgt
    87781 tcaagacgca gaccgcatct acatccttgc agctggaaca tcttaccatg caggatttgc
    87841 ttctaagaaa atgttggaag aattgacaga tacaccagtt gaacttggaa tctcatctga
    87901 gtggggctac ggtatgccac ttctcagcaa gaaaccactc ttcatcttta tcagccaatc
    87961 tggtgaaaca gcggatagtc gtcaagtttt ggtcaaggct aatgaaatgg gaattccaag
    88021 cttaacagtg acaaacgttc caggttcaac cctctcacgt gaagccaact ataccatgct
    88081 ccttcacgca ggtcctgaaa ttgccgtggc atcaactaaa gcctatacag cgcaaatcgc
    88141 agcccttgcc ttccttgcaa aagcagtcgg agaagcaaat ggtaatgcta aagcgcaagc
    88201 ctttgacctg gttcatgaat tgtcaatcgt agctcagtct atcgaatcaa ctctttcaga
    88261 gaaagaaacc attgaagcca aggttcgtga acttcttgaa acaactcgta acgcctttta
    88321 catcggacgt ggtcaagatt actacgtagc catggaagca agtctcaaac tcaaagagat
    88381 ttcttatatc cagtgtgaag gttttgcggc aggagaactc aagcacggaa ccattgcctt
    88441 gattgaagaa ggaacgcctg ttttggctct cttgtcagat ccagttcttg ccaaccatac
    88501 tcgtggaaat atccaagagg tcgcagcccg tggtgccaaa gtcctcacta tcgcagaaga
    88561 gaatgtagcc aaagataccg acgatatcgt ccttacgacc gtatatccat acctctcacc
    88621 aatttcaatg gtcgtaccaa cgcaattagt cgcttacttt gcaaccctcc accgtggcct
    88681 cgatgtggat aaaccacgta accttgctaa gtcagtaacg gtagaataag ctaaaaaagt
    88741 ctagttattt aggctttttc taatgagcaa attggttgct tgtacttaag attcgtgtta
    88801 gaataatttt tcaaattgaa ggacagagat agacaaggag aatcacaatg gtagaattgg
    88861 gaatttcaac atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg
    88921 ctgaacgcat tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggacg
    88981 tatatgggat tggcgagcac catcgggcgg attttgcagt atcagcccca gagattgtcc
    89041 tggccgctgg ggcagtcaat accaagaaaa tccgtttgac cagcgcagtc agcattctgt
    89101 caagcatgga cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg
    89161 gacgatcgga gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt
    89221 atgacttgaa agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca
    89281 atgaaaagac caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag
    89341 tttatcctcg tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg
    89401 aatcaacagt gaagattgct caggctggtc taccgattgt atatgctatt attggtggta
    89461 atccacgtta ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggcc
    89521 atgctgacaa agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg
    89581 agcaggcggt gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag
    89641 accgtccgca ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg
    89701 gcgccatgtt tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg
    89761 atttaggatt ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg
    89821 ttctgagagc tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg
    89881 ctatgaaaga ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac
    89941 gaaaattaat cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag
    90001 ttctcttttt tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct
    90061 gcaaatagga gtttgttttc gtttttaatt cctgtatttg gaagttcagc ttgtctatct
    90121 ggggttgcag gtatattttt cttgctagag ttttctaccg attcgtttcg aaccgcttct
    90181 tttacagatg atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct
    90241 tggctaggtt tattttccgc atcagctact ttggtatctg gtttagtaga atcaggtcta
    90301 gcttctggag ctggatcttg atgttcaggg tgagaagctt cattttgatg ttcaggcttg
    90361 gaaggggttg agtctggttt ctcttctgca gttgactcat ggctagttcc attttgagag
    90421 actcgaagaa cagtagctgt aagggcattc aatttcaagc ctttttcagt ccattcaagt
    90481 cctttcgggt tggcaattcc gactgatcct gcttggtttt catctgccaa aacttccgca
    90541 tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc gagctttttc atccgcattg
    90601 acaaagactg cgtagatatc gccgtttgga gcagtgattt gatagccaat cactacatcc
    90661 tctttttcca caccattttg gcctgggaca gtgatgaggt ggacacggtc tttgatatct
    90721 tgaagactct taagtcggaa ggcatctgta gattgacgaa gggcaatcaa acctttcata
    90781 tagtcacggc tcttgacatt ttcaggataa gctttaccat ctgtagcctt agtccagtca
    90841 aacttgttga ctgcatcact agaatcgtaa gagtcatgga tgaagtaagg atagtcaaat
    90901 gggttgccgt ccttatcacg caacaagtga gatttgtttg gaaccttatc ctctgctact
    90961 ggagtcttgt aggctgggtc acggaattgt ttagtacgtc catattcctg accggagtgg
    91021 ataaatggag ttccttgagc tgtcaagacc atgagatttc caagtcgtaa acgacggtgg
    91081 atttcagcat agttctcagc cttgcttggg tcttttttga tagactgggc aatgatgtca
    91141 aagagggtca agttatcatg ggctgcgatg tattggatga catctccagg gctgtcagct
    91201 tcaaagttag ttggttgagc aatgagattt ttaaagatgg tgttgacatc acgcttgcca
    91261 cctgtgataa aggcaggttg accttcgttt ggataaccag atttgaggtt gttacggatg
    91321 tcatctgaaa agacagcgac agtatcggta tgtttcatcc aatcttggtc agcagcttta
    91381 gtaggcatgt tttcatcacc ggcataggtt ctccaacctt caccaagcat gatgaggttt
    91441 ggattgaggg cgcgtgcagc cttgtaagct tcttcgatag aagtggcgtc atggtctccc
    91501 atcatatcga aacggaagcc atccactttg taggtatcaa ctaggtattt gatagagtca
    91561 attaggagcc gtttggtcat atggtgggtt gtccccaagc gtccaccacc aaagctagtt
    91621 cgaggtgtgc catcggcatc cataaagtgg tagtagtttg gttccaaatc ttcaaagaga
    91681 tcgactttgg ctgtgtggtt ataaacgaca tctaggatag ctcccatacc acgtttgtgg
    91741 atttcgttga tgaggttttt aaattctgcg attcgttttt ctggattctt aggatcgctt
    91801 gagtacatac cagtcaagga gaagtagttt tgagggtcat atccccagtt gtagttgctg
    91861 ttgcttgaag cgtagtcaga caagcgttca tggtttttca attcattgac aaagtagtaa
    91921 gacaagactg gaaggagctg gatatgggtt acacccaagt ctttgagata gtctagtttt
    91981 tcaatgaagg cttcaaaagt cccaaatggt ttggtcaagt cttttgcaat ggcaggatct
    92041 gaagtgaaat cacgcacatg agcttcgtag ataacggcgt cttcacgagt cttgaaattg
    92101 tgaatcttac cataagtcaa gtcttgaggt ccgagtttag ctggatctac aaaggcggct
    92161 ttagccactt tatgggcatc gtcaatcttg gaatcgtcgc tattccaagc agcaagagat
    92221 ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac gctcgatttg gtattgataa
    92281 tagtagccag tgaaatctgt gattccgagt ttgtttgtgc tgtctagagt ttgtttccaa
    92341 gttcctcttt cccctttttc aagagcgaca gttccaacta ctttgtcagg gtcattcttg
    92401 tcgtagacaa caacagaaac cttatcagca cttggtgacc aaagggtcaa atcaacttgt
    92461 tttccttctt cttttaggtc agctcccagt ttgccatcat agctgtatgt ctcatctttc
    92521 aggcgccagc ttgttttggt agtgaattgg tcggaattgt agctaacagt ataaggatgt
    92581 tttgtgtcag agaaatctcc gctgtaggtc actttcttac cagcttcatc gattgcaaca
    92641 tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt tggagtgttt gaggatatct
    92701 tcttttttag caccgacaag tgttgaaaag ctactttcaa tgctagaagt gcctacgtgt
    92761 tgggctcctg tcatacggat atcatggaca tagtatggat ttgtgtaaat cgattcatca
    92821 tcgtctttta ggaaaatttg gctatgattt ttcaaatctg tgaacttata attttcttta
    92881 cggattttca cgtcgtctcc ttgtttgctc tcatctagta ataaaaatcc aaattctctt
    92941 gcggcttcat taagaggaat gtcgatatag cggccatatt tgcctgtagc cgtaaagtct
    93001 gttccgtcag gccattgagc gctacttgga tttttcacat ctccccagta ccagagagat
    93061 ttcttgtcat agttgccatc tgtgcggtag tagttgacgc gaacagttcc tgcaggctgt
    93121 ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag cttcgttcat ttttggaact
    93181 agtttttcta cagatttatc gccggttaga ttttttccag ctgtattgtt gatgaggaag
    93241 ctaattttct tggcttgttc tccctttaat ttgacatcta ggtaatagcc gtagtcatct
    93301 ttcttggcat ccttgaagga caaagctccg tttggccagt tttcagatgg tttttcaaca
    93361 tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt caggaagttt tttgacatgg
    93421 atacggaagt agttatcttc gatgggctct tctgccttag tttcagttgt tactggacta
    93481 gtagaagtag ttggctcact tgaacgatct tgtccagttt gtggtgctgg atcggctggg
    93541 cttgcagcag gtttttcttc tgttttctct agggaagcgt ttgcatttcc aggtgaagaa
    93601 atatcacttt cgttcttacc agagccagct gctgtatcag taagaggttg ggcaagggtg
    93661 gttgtatttc tgttgttggg ttcgttagtg gttggtgtac tttcgtcgga tgagatagtt
    93721 ggtgtagcca tggcaagcaa gacaaggctt gtgccgataa ggacagaacc agttccattt
    93781 ttgagggaac ggatgctgta gaccattttt ttctcagtgt gagatggtgt ttttctcata
    93841 atgattctcc aatcaataaa tttctatatc agtatagcat gtagtaaaac aatatgcaag
    93901 cgttttcttt gatttgtgaa agaaattctt acttttgaga agttttccgt actattttat
    93961 atatcagtat aaatgacgga gataaaaatg tcacgtaagc caagccgtgt tattaggaag
    94021 atgatgtgtt ctcagctatt tttattcaga aattgatctc taacattacc aataaaaaag
    94081 aaaaatatct tgacaagcaa gggaaaattt tgttacaata atagacggta ctttttactt
    94141 ttggtctctc aagagtgtac agggacgtgc tgacaaatgt tgcaaaagta cacacagatg
    94201 atatctgtca ccaagtgtat catcaccaaa aataaaaaaa cacaggagaa tgtagatgcc
    94261 tacaattaac caattggttc gcaaaccgcg taaatcaaaa gtagaaaaat ctaaatcacc
    94321 agctttgaac gttggttaca atagtcataa aaaagttcaa acaaacgttt cttcaccaca
    94381 aaaacgtggt gttgcaactc gtgttggaac aatgacacct aaaaaaccta actcagccct
    94441 tcgtaaattc gctcgtgtac gtttgagcaa ccttatcgaa gttactgcct acatcccagg
    94501 tatcggacac aacttgcaag agcacagcgt ggtgcttctt cgcggtggac gtgtaaaaga
    94561 ccttccaggg gtacgttacc atatcgtccg tggtgcactt gatactgcag gtgttaacga
    94621 tcgtaaacaa ggccgttcta aatacggtac taaacgtcca aaagcataag gaaaggggat
    94681 aaagagaaat gagtcgtaaa aatagagctc caaaacgtga cgtattgcca gatccgctat
    94741 acaattcaca actagttact cgtcttatca accgcgttat gcttgatggt aaacgtggta
    94801 ctgctgcttc aatcgtttac ggtgcttttg agcaaatcaa agaagctact ggcaacgatg
    94861 cacttgaagt atttgaaaca gctatggaaa acatcatgcc tgtacttgaa gtacgtgcac
    94921 gtcgtgttgg tggttctaac taccaagtcc cagttgaagt tcgtccagaa cgtcgtacaa
    94981 cacttggact tcgttggttg gtaacaatcg ctcgtcttcg tggtgaacac acaatgcaag
    95041 accgtcttgc aaaagaaatc ttggatgctg ctaacaacac tggtgcagca gttaagaaac
    95101 gtgaagatac tcaccgtatg gctgaagcta accgtgcatt cgcacacttc cgttggtaag
    95161 ataggatgcg aaagcgttaa gaaagtccca gagaaaatag ggaatcgaag caggttgcgg
    95221 ttgcaaccaa tgagattcat ctttttctcc agacttttag cttgagctca actaaatcat
    95281 gatgctagga acggtaagga tgcaaggtaa aaataggaaa ctgacgcagt attcgacgaa
    95341 tacaaggagt tttatctttt tcacgcagca tcccgttcca gctcacatcg gctaactaac
    95401 tttagcccgg gttcaaatta gctaaatcga ttagtattag ctataactca gcttaccatc
    95461 tcgtaagttg aaaccaacaa tagcatgaaa acattgagaa cgggtaggtc ctgcctatcc
    95521 gtttttatta aaatcgtgtt ataatagaat agaaatcaaa aataaatagg agaaacaaac
    95581 ctcatggcac gcgaattttc acttgaaaaa actcgtaata tcggtatcat ggctcacgtc
    95641 gatgccggta aaacaacaac tactgagcgt attctttact acactggtaa aatccacaaa
    95701 atcggtgaaa ctcacgaagg tgcgtcacaa atggactgga tggagcaaga gcaagaacgt
    95761 ggtatcacga tcacatctgc tgcgacgaca gctcaatgga acaaccaccg cgtaaacatc
    95821 atcgacacac caggacacgt ggacttcaca atcgaagtac aacgttctct tcgtgtattg
    95881 gatggtgcgg ttaccgttct tgactcacaa tcaggtgttg agcctcaaac tgaaacagtt
    95941 tggcgtcaag caactgagta cggagttcca cgtatcgtat ttgccaacaa aatggacaaa
    96001 atcggtgctg acttccttta ctctgtaagc acacttcacg atcgtcttca agcaaatgca
    96061 cacccaatcc aattgccaat cggttctgaa gatgacttcc gtggtatcat tgacttgatc
    96121 aagatgaaag ctgaaatcta tactaacgac cttggtacgg atatccttga agaagacatc
    96181 ccagctgaat accttgacca agctcaagaa taccgtgaaa aattgattga agcagttgct
    96241 gaaactgacg aagaattgat gatgaaatac ctcgaaggtg aagaaatcac taacgaagaa
    96301 ttgaaagctg gtatccgtaa agcgactatc aacgttgaat tcttcccagt attgtgtggt
    96361 tcagccttca aaaacaaagg tgttcaattg atgcttgatg cggttatcga ctaccttcca
    96421 agcccacttg acatcccagc aatcaaaggt attaacccag atacagacgc tgaagaaatt
    96481 cgtccagcat ctgacgaaga gccatttgca gctcttgcct tcaagatcat gactgaccca
    96541 ttcgtaggtc gtttgacatt cttccgtgtt tactcaggtg ttcttcaatc aggttcatac
    96601 gtattgaata cttctaaagg taaacgtgaa cgtatcggac gtatccttca aatgcacgct
    96661 aacagccgtc aagaaatcga cactgtttac tcaggtgata tcgctgctgc cgttggtttg
    96721 aaagatacta caactggtga ctcattgaca gatgaaaaag ctaaaatcat ccttgagtca
    96781 atcaacgttc cagaaccagt tatccaattg atggttgagc caaaatctaa agctgaccaa
    96841 gacaagatgg gtatcgccct tcaaaaattg gctgaagaag atccaacatt ccgcgttgaa
    96901 acaaacgttg aaactggtga aacagttatc tcaggtatgg gtgaacttca ccttgacgtc
    96961 cttgttgatc gtatgcgtcg tgagttcaaa gttgaagcga acgtaggtgc tcctcaagta
    97021 tcttaccgtg aaacattccg cgcttctact caagcacgtg gattcttcaa acgtcagtct
    97081 ggtggtaaag gtcaattcgg tgatgtatgg attgaattta ctccaaacga agaaggtaaa
    97141 ggattcgaat tcgaaaacgc aatcgtcggt ggtgtggttc ctcgtgaatt tatcccagcg
    97201 gttgaaaaag gtttggtaga atctatggct aacggtgttc ttgcaggtta cccaatggtt
    97261 gacgttaaag ctaagcttta tgatggttca tatcacgatg tcgactcatc tgaaactgcc
    97321 ttcaagattg cggcttcact ttcccttaaa gaagctgcta aatcagcaca accagctatc
    97381 cttgaaccaa tgatgcttgt aacaatcact gttccagaag aaaaccttgg tgatgttatg
    97441 ggtcacgtaa ctgctcgtcg tggacgtgta gatggtatgg aagcacacgg taacagccaa
    97501 atcgttcgtg cttacgttcc acttgctgaa atgttcggtt acgcaacagt tcttcgttct
    97561 gcatctcaag gacgtggtac attcatgatg gtatttgacc actacgaaga tgtacctaag
    97621 tcagtacaag aagaaattat taagaaaaat aaaggtgaag actaatccgt cctcactcta
    97681 gaaggaagtc acttagtggc ttccttttgt ctttagaaaa tacctctaaa tatggtaaaa
    97741 tagtagaaga ataatgtgag gaaaatgaat gtcaaatagt tttgaaattt tgatgaatca
    97801 attggggatg cctgctgaaa tgagacaggc tcctgcttta gcacaggcca atattgagcg
    97861 agttgtggtt cataaaatta gtaaggtatg ggagtttcat ttcgtatttt ctaatatttt
    97921 accgattgaa atctttttag aattaaagaa aggtttgagc gaagaatttt ctaagacagg
    97981 caataaagct gtttttgaaa ttaaggctcg gtctcaagaa ttttcaaatc agctcttgca
    98041 gtcctactat agggaggctt tctctgaagg tccatgtgct agtcaaggtt ttaagtccct
    98101 ttatcaaaat ttgcaagttc gtgctgaggg taatcagcta tttattgaag gatctgaagc
    98161 gattgataag gaacatttta agaagaatca tcttcctaat ttagccaaac aacttgaaaa
    98221 gtttggtttt ccaactttta actgtcaagt cgagaagaat gatgtcctga cccaagagca
    98281 ggaagaggcc tttcatgctg aaaatgagca gattgttcaa gctgccaatg aggaagcgct
    98341 ccgtgctatg gaacaactgg agcagatggc acctcctcca gcggaagaga aaccagtctt
    98401 tgattttcaa gcgaaaaaag ctgcagctaa acccaagctg gataaggcgg agattactcc
    98461 tatgatcgaa gtgacgacag aggaaaatcg tctggtattt gaaggggttg tttttgatgt
    98521 ggagcaaaaa gtgactagaa caggtcgtgt tttaatcaac tttaaaatga cggactatac
    98581 ttcaagtttt tctatgcaaa agtgggttaa aaacgaggaa gaggcccaga agtttgacct
    98641 catcaagaag aattcttggc tccgagttcg agggaatgtg gagatgaata acttcacacg
    98701 cgatttgact atgaacgtac aggatctgca ggaagttgtt cactatgagc ggaaggattt
    98761 gatgccagaa ggtgagcgtc gggttgagtt tcatgctcat actaacatgt cgactatgga
    98821 tgctttgcca gaggtcgaag agattgttgc aacagctgct aagtggggac acaaggcggt
    98881 tgctatcacg gaccatggga atgtccagtc ctttccacat ggctataagg cggctaagaa
    98941 agcgggaatc cagctgatct atgggatgga agccaatatc gtggaggacc gtgtccctat
    99001 cgtctataac gaagtggaga tggacttgtc agaagcaacc tacgtggtct ttgacgtgga
    99061 aacgacggga ctttcagcta tctataatga cttgattcag gttgcggctt ctaagatgta
    99121 caaggggaat gttattgctg aatttgatga atttatcaat cctgggcatc ccttgtcagc
    99181 ctttactaca gagttaactg gaattacaga tgatcatgtc aaaaatgcca aaccactaga
    99241 acaagttttg caagaattcc aagaattttg caaggatacg gtcctagttg cccacaatgc
    99301 tacctttgac gttggcttta tgaatgctaa ttatgagcgg catgatcttc caaagattag
    99361 tcagccagtt attgatacgc tggagtttgc tagaaacctc tatcctgagt ataaacgcca
    99421 tggtttgggg cctttgacca agcgttttgg tgtggccttg gaacatcacc acatggccaa
    99481 ctacgatgcg gaagcgactg gtcgtctgct tttcatcttt atcaaagagg tagcagaaaa
    99541 acatggtgtg accgatttag ctagactcaa cattgatcta atcagtccag attcttacaa
    99601 aaaagctcgg atcaagcatg cgaccatcta tgtcaagaat caggtaggtc taaaaaatat
    99661 ctttaagctg gtttccttgt ctaataccaa gtattttgaa ggagtgccac ggattccgag
    99721 aacggttcta gatgcccatc gagagggctt gattttaggt tcagcctgtt cagagggtga
    99781 agtttttgac gtggtcgttt ctcaaggtgt ggatgcggcg gttgaggtgg ccaagtatta
    99841 tgattttatc gaggtcatgc caccggctat ctatgcaccc ttgattgcca aagagcaggt
    99901 caaggatatg gaggaactcc agaccattat caagagtttg atagaggttg gagaccgcct
    99961 tggcaagcct gttctggcta cgggaaatgt tcactatatc gaaccggaag aagagattta
   100021 tcgtgaaatt atcgtccgta gtttgggaca gggtgcgatg attaatcgaa ctatcggtca
   100081 tggtgaacat gcccaaccag caccacttcc aaaggctcat tttcgaacga ctaatgagat
   100141 gttggatgaa tttgcctttt tgggagagga actggctcgt aaactggtta ttgaaaacac
   100201 caatgccttg gcagaaatat ttgaatccgt tgaagtcgtt aagggtgact tgtatacgcc
   100261 tttcatcgac aaggctgaag aaacagttgc tgagttgacc tataagaaag cttttgagat
   100321 ttatggaaat ccgctgccag atattgttga tttgcggatt gaaaaagaat taacatccat
   100381 actggggaat ggatttgctg tgatttatct ggcatcgcag atgctggtgc aacgttctaa
   100441 tgaacggggt tatttggttg gttctcgtgg gtctgtcgga tctagtttcg ttgcgaccat
   100501 gattgggatt acggaggtca atcctctctc tcctcactat gtctgtggtc agtgtcagta
   100561 cagtgagttt atcacagatg gttcgtacgg ttcaggattt gatatgcccc ataaggactg
   100621 tccaaactgt ggtcacaaac tcagtaaaaa cggacaggat attccgtttg agaccttcct
   100681 tggttttgat ggggataagg ttcctgatat tgacttgaac ttctcgggag aagatcagcc
   100741 tagcgcccac ttggatgtgc gtgatatctt tggtgaagaa tatgccttcc gtgcgggaac
   100801 ggttggtacg gtagctgcca agactgccta tggatttgtc aagggttacg agcgagatta
   100861 tggcaagttt tatcgtgatg cagaagtaga acgcctcgct caaggagcgg cgggtgtcaa
   100921 gcggacaaca ggccaacacc cggggggaat cgttgttatt ccgaactaca tggatgtcta
   100981 cgattttacg cctgtccagt atccagcaga tgatgtcacg gctgaatggc agaccactca
   101041 ctttaacttc cacgatatcg atgagaacgt cctcaaactc gatgtactgg gacatgatga
   101101 tccgaccatg attcgaaaac ttcaggattt gtctggtatt gaccctaata aaattcctat
   101161 ggatgacgaa ggcgtgatgg cactcttttc tgggactgat gtactagggg taacacctga
   101221 acaaattgga acgcctacgg gtatgttggg gattccagag tttggaacaa atttcgtacg
   101281 tggaatggta gacgaaaccc atccgacaac ctttgcggaa ttgcttcagc tgtctggtct
   101341 gtcccacggt actgacgttt ggttggggaa tgctcaggat ctgattaagc aaggaatagc
   101401 ggacctatcg actgttatcg gttgtcggga cgacatcatg gtttacctca tgcatgcggg
   101461 tctggaacct aagatggcct ttaccattat ggaacgggta cgtaagggtt tgtggctaaa
   101521 gatttcagaa gaggagagaa atggctatat cgaagccatg aaggctaata aggtgccaga
   101581 gtggtatatc gaatcctgtg ggaaaattaa gtacatgttc cctaaggccc atgcggcagc
   101641 ctacgttatg atggccttgc gtgtagctta cttcaaggtt caccatccta tttattacta
   101701 ctgtgcttac ttctccattc gtgctaaggc ttttgatatc aagaccatgg gtgcgggctt
   101761 ggaggtcatc aagcgcagaa tggaagaaat ctctgaaaaa cggaagaaca atgaagcctc
   101821 taatgtggaa atcgatctct atacaactct tgagattgtc aatgagatgt gggaacgagg
   101881 tttcaagttt ggtaaattag atctctaccg tagtcaggcg acagagttcc tcatcgacgg
   101941 ggataccctt atcccaccat ttgtagcaat ggatggtctg ggagagaacg ttgccaagca
   102001 actggtgcgg gcgcgtgaag agggagaatt cctctctaaa acagaactac gcaagcgtgg
   102061 tggactctca tcaaccttgg ttgaaaagat ggatgagatg ggtattcttg gaaatatgcc
   102121 agaggataac cagttgagtt tgtttgatga gttgttttaa aaaattgctt aataatctat
   102181 taaaagaggc taacgtatat ccaatagatt tacattagct ttcttttttg ttaaaatagt
   102241 ctatggaaag agggtgagag tatgtcaaag atgagtataa gcatccgtct ggatagtgag
   102301 gttaaggagc aggcccaaca ggtgtttagt aatctgggaa tggatatgac aacagctatt
   102361 aatattttcc ttcgtcaggc aattcaatat cagggattac cttttgatgt tagactagac
   102421 gaaaatcgga agttgctcca agcgttaacg gatttagacc aaaatcgtaa tatgagccag
   102481 tcttttgaat cagtctcaga tttgatggag gacttacgtg cttaagattc gttatcataa
   102541 acagtttaaa aaagatttta agttggctat gaagcgtggt ttgaaggcag aattattaga
   102601 agaagttttg aattttctgg ttcaagaaaa agaacatcct gccagatatc gtgatcattc
   102661 attgacggca tccaagcatt ttcaaggagt tcgtgaatgc catacccagc cagattggct
   102721 tttggtttat aaagtagaca agtcggaatt gattttaaat ttgctgagga caggcagtca
   102781 cagtgattta ttttaatcta ttttaagggg gttctcatga aactaagaat atttgcggaa
   102841 gataagccgg ctaagaaggt atttgaatat caattagaac ttgctgatcg tacaattctt
   102901 ctatcgacag cactcttgtc aggtgctatt gctttagcag gaatcttttc tgctttgaaa
   102961 gaaaaataaa aatagaaaag agaaaacaga atggttttac caaattttaa agaaaatcta
   103021 ggaaaatatg cgaaattgtt ggttgcgaac ggaattaacg tgcaacctgg tcacactttg
   103081 gctctctcta ttgatgtgga gcaacgtgaa ttggcacatc taatcgtgaa agaagcttat
   103141 gccttgggtg cgcatgaggt catcgttcag tggacagatg atgtgattaa ccgtgagaaa
   103201 ttcctccatg ccccgatgga gcgtttggac aatgtgccag aatacaagat tgctgagatg
   103261 aactatcttt tggagaacaa ggctagccgt cttggggttc gttcatctga tccaggtgcc
   103321 ttgaacggag tggacgctga caagctttca gcttctgcta aagctatggg acttgccatg
   103381 aagcctatgc gtatcgcaac tcaatctaac aaggttagct ggactgtagc agccgctgct
   103441 ggacttgagt gggctaagaa agtcttccca aatgctgcga gcgacgaaga agcagttgat
   103501 ttcctttggg atcaaatctt caaaacttgt cgtgtctacg aagcagatcc tgttaaggct
   103561 tgggaggaac atgcagccat tctcaagagc aaggccgata tgcttaataa ggagcaattt
   103621 tcagcccttc actacacagc gccaggaaca gatttaacac ttggtttgcc aaagaaccac
   103681 gtttgggaat cagctggtgc tgtcaatgca cagggcgaag aattcttgcc aaatatgccg
   103741 acagaagagg tcttcacagc gcctgacttc cgtcgtgcag atggttatgt cacttctaca
   103801 aaaccgctta gctacaacgg aaatatcatt gaaggcatta aggtgacctt taaggatgga
   103861 caaatcgtag atatcactgc tgagaagggt gatcaggtta tgaaagacct tgtctttgaa
   103921 aatgcgggtg cgcgtgcctt gggtgaatgt gccttggtac cagatccaag tccaatttct
   103981 cagtcaggca ttaccttttt taacaccctt ttcgatgaaa atgcgtcaaa ccacttggct
   104041 atcggtgcag cctatgcgac tagcgttgtt gatggagcgg agatgagcga agaggagctt
   104101 gaagctgcag ggcttaaccg ttcagatgtt cacgtagact ttatgattgg ttctaaccaa
   104161 atggatatcg atggtattcg tgaggatgga acgcgggtac ctcttttccg taatgggaat
   104221 tgggcaaatt aaggagataa tatgttagga agtatgttcg ttggtctcct agtgggattt
   104281 ttagcaggtg ctatgaccaa tcgtggagag cgaatgggat gttttggaaa aatgtttctc
   104341 ggttggatcg gagcctttct aggtcacttg ctctttggaa cttgggggcc agttttatca
   104401 ggaacagcta ttatcccagc gattttagga gccatgattg ttttagctat tttttggaga
   104461 cgaggaagtt aatttcctaa atctgatact caatgaaaat caaagagcaa actaggaaac
   104521 tagccgcagg ttgctcaaag cactg
//
LOCUS       DAVHSH010000003        96134 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000003 DAVHSH010000000
VERSION     DAVHSH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 96134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.003"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(1..233)
                     /locus_tag="VVR08_000245"
                     /pseudo
     CDS             complement(1..233)
                     /locus_tag="VVR08_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(617..1813)
                     /gene="tuf"
                     /locus_tag="VVR08_000246"
     CDS             complement(617..1813)
                     /gene="tuf"
                     /locus_tag="VVR08_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6074223.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2724..3593)
                     /locus_tag="VVR08_000247"
     CDS             complement(2724..3593)
                     /locus_tag="VVR08_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6074224.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3806..4336)
                     /locus_tag="VVR08_000248"
     CDS             complement(3806..4336)
                     /locus_tag="VVR08_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6074225.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKKMKNNRF"
     gene            complement(4294..5400)
                     /locus_tag="VVR08_000249"
     CDS             complement(4294..5400)
                     /locus_tag="VVR08_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU6074226.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5511..5765)
                     /locus_tag="VVR08_000250"
     CDS             complement(5511..5765)
                     /locus_tag="VVR08_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074227.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6123..6656)
                     /locus_tag="VVR08_000251"
     CDS             complement(6123..6656)
                     /locus_tag="VVR08_000251"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6074228.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6643..6969)
                     /locus_tag="VVR08_000252"
     CDS             complement(6643..6969)
                     /locus_tag="VVR08_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6074229.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7203..8921
                     /locus_tag="VVR08_000253"
     CDS             7203..8921
                     /locus_tag="VVR08_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU6074230.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9032..9379
                     /locus_tag="VVR08_000254"
     CDS             9032..9379
                     /locus_tag="VVR08_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6074231.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9657..10493)
                     /locus_tag="VVR08_000255"
     CDS             complement(9657..10493)
                     /locus_tag="VVR08_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6074232.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10506..11135)
                     /locus_tag="VVR08_000256"
     CDS             complement(10506..11135)
                     /locus_tag="VVR08_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6074233.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11145..11786)
                     /locus_tag="VVR08_000257"
     CDS             complement(11145..11786)
                     /locus_tag="VVR08_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6074234.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11932..13161)
                     /locus_tag="VVR08_000258"
     CDS             complement(11932..13161)
                     /locus_tag="VVR08_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU6074235.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13151..14317)
                     /locus_tag="VVR08_000259"
     CDS             complement(13151..14317)
                     /locus_tag="VVR08_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6074236.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14461..15474
                     /locus_tag="VVR08_000260"
     CDS             14461..15474
                     /locus_tag="VVR08_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU6074237.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
     gene            complement(15519..15938)
                     /locus_tag="VVR08_000261"
     CDS             complement(15519..15938)
                     /locus_tag="VVR08_000261"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU6074238.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15949..17355)
                     /gene="atpD"
                     /locus_tag="VVR08_000262"
     CDS             complement(15949..17355)
                     /gene="atpD"
                     /locus_tag="VVR08_000262"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU6074239.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17441..18319)
                     /locus_tag="VVR08_000263"
     CDS             complement(17441..18319)
                     /locus_tag="VVR08_000263"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU6074240.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18335..19840)
                     /locus_tag="VVR08_000264"
     CDS             complement(18335..19840)
                     /locus_tag="VVR08_000264"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU6074241.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19855..20391)
                     /locus_tag="VVR08_000265"
     CDS             complement(19855..20391)
                     /locus_tag="VVR08_000265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU6074242.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20391..20885)
                     /gene="atpF"
                     /locus_tag="VVR08_000266"
     CDS             complement(20391..20885)
                     /gene="atpF"
                     /locus_tag="VVR08_000266"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU6074243.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20899..21615)
                     /gene="atpB"
                     /locus_tag="VVR08_000267"
     CDS             complement(20899..21615)
                     /gene="atpB"
                     /locus_tag="VVR08_000267"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU6074244.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21650..21850)
                     /locus_tag="VVR08_000268"
     CDS             complement(21650..21850)
                     /locus_tag="VVR08_000268"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU6074245.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21925..22875)
                     /locus_tag="VVR08_000269"
                     /pseudo
     CDS             complement(21925..22875)
                     /locus_tag="VVR08_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155340.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23309..23707)
                     /locus_tag="VVR08_000270"
     CDS             complement(23309..23707)
                     /locus_tag="VVR08_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074246.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(24080..24562)
                     /gene="greA"
                     /locus_tag="VVR08_000271"
     CDS             complement(24080..24562)
                     /gene="greA"
                     /locus_tag="VVR08_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU6074247.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(24633..26288)
                     /gene="mltG"
                     /locus_tag="VVR08_000272"
     CDS             complement(24633..26288)
                     /gene="mltG"
                     /locus_tag="VVR08_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU6074248.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(26369..26863)
                     /locus_tag="VVR08_000273"
     CDS             complement(26369..26863)
                     /locus_tag="VVR08_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074249.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(26860..27324)
                     /locus_tag="VVR08_000274"
     CDS             complement(26860..27324)
                     /locus_tag="VVR08_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074250.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(27334..28668)
                     /locus_tag="VVR08_000275"
     CDS             complement(27334..28668)
                     /locus_tag="VVR08_000275"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU6074251.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(28679..29296)
                     /locus_tag="VVR08_000276"
     CDS             complement(28679..29296)
                     /locus_tag="VVR08_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6074252.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(29344..32442)
                     /locus_tag="VVR08_000277"
     CDS             complement(29344..32442)
                     /locus_tag="VVR08_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6074253.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(32535..33701)
                     /locus_tag="VVR08_000278"
     CDS             complement(32535..33701)
                     /locus_tag="VVR08_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6074254.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(33709..34803)
                     /locus_tag="VVR08_000279"
     CDS             complement(33709..34803)
                     /locus_tag="VVR08_000279"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6074255.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(34961..35682)
                     /locus_tag="VVR08_000280"
                     /pseudo
     CDS             complement(34961..35682)
                     /locus_tag="VVR08_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(35707..36402)
                     /locus_tag="VVR08_000281"
     CDS             complement(35707..36402)
                     /locus_tag="VVR08_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074256.1"
                     /translation="MRKKVIEGLIYAEKSFFDKNQSGELTSAIVNDTSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVYSRSKGSSVA
                     LENLLAVPKEKFE"
     gene            complement(36408..36641)
                     /locus_tag="VVR08_000282"
     CDS             complement(36408..36641)
                     /locus_tag="VVR08_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEU6074257.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            complement(36813..38771)
                     /locus_tag="VVR08_000283"
     CDS             complement(36813..38771)
                     /locus_tag="VVR08_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6074258.1"
                     /translation="MKRSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDILSVKSGGMLQNFGLEPGEVNEKAKAVGLDTYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAGAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(38975..40597)
                     /locus_tag="VVR08_000284"
     CDS             complement(38975..40597)
                     /locus_tag="VVR08_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6074259.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            40703..42148
                     /locus_tag="VVR08_000285"
     CDS             40703..42148
                     /locus_tag="VVR08_000285"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU6074260.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMGIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(42194..42376)
                     /locus_tag="VVR08_000286"
     CDS             complement(42194..42376)
                     /locus_tag="VVR08_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6074261.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGLKNVFTK"
     gene            complement(42477..42995)
                     /locus_tag="VVR08_000287"
     CDS             complement(42477..42995)
                     /locus_tag="VVR08_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU6074262.1"
                     /translation="MIRYLDQYEDVILCENKRYYLNFPTLESLDSLELDQEIFVREAS
                     PVYQALLEQSFETELRNQINAAILVEKTDFARIKMTLSNYFYKVKQQYPLTEKQQELY
                     DILGDVNPEYALKYMTAFLLKFLKKDQLMQKCRDIFVDSLVVLGYIVQNEDGKYELAI
                     DFDKERLTFYLA"
     gene            complement(43032..43544)
                     /locus_tag="VVR08_000288"
     CDS             complement(43032..43544)
                     /locus_tag="VVR08_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU6074263.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLRDSDF"
     gene            complement(43630..44565)
                     /locus_tag="VVR08_000289"
     CDS             complement(43630..44565)
                     /locus_tag="VVR08_000289"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU6074264.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(44636..44935)
                     /locus_tag="VVR08_000290"
     CDS             complement(44636..44935)
                     /locus_tag="VVR08_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU6074265.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(44925..45674)
                     /locus_tag="VVR08_000291"
     CDS             complement(44925..45674)
                     /locus_tag="VVR08_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU6074266.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(45728..46087)
                     /locus_tag="VVR08_000292"
     CDS             complement(45728..46087)
                     /locus_tag="VVR08_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU6074267.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(46089..47489)
                     /locus_tag="VVR08_000293"
     CDS             complement(46089..47489)
                     /locus_tag="VVR08_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU6074268.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(47784..48023)
                     /locus_tag="VVR08_000294"
     CDS             complement(47784..48023)
                     /locus_tag="VVR08_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU6074269.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(48055..48525)
                     /gene="ssbA"
                     /locus_tag="VVR08_000295"
     CDS             complement(48055..48525)
                     /gene="ssbA"
                     /locus_tag="VVR08_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU6074270.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(48537..48827)
                     /locus_tag="VVR08_000296"
     CDS             complement(48537..48827)
                     /locus_tag="VVR08_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU6074271.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(48980..50326)
                     /gene="asnS"
                     /locus_tag="VVR08_000297"
     CDS             complement(48980..50326)
                     /gene="asnS"
                     /locus_tag="VVR08_000297"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU6074272.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(50342..50708)
                     /locus_tag="VVR08_000298"
                     /pseudo
     CDS             complement(50342..50708)
                     /locus_tag="VVR08_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(50701..51888)
                     /locus_tag="VVR08_000299"
     CDS             complement(50701..51888)
                     /locus_tag="VVR08_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6074273.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(51885..52373)
                     /locus_tag="VVR08_000300"
     CDS             complement(51885..52373)
                     /locus_tag="VVR08_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU6074274.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            52694..53242
                     /locus_tag="VVR08_000301"
     CDS             52694..53242
                     /locus_tag="VVR08_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6074275.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTYPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(53520..54248)
                     /gene="yaaA"
                     /locus_tag="VVR08_000302"
     CDS             complement(53520..54248)
                     /gene="yaaA"
                     /locus_tag="VVR08_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU6074276.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(54327..54491)
                     /locus_tag="VVR08_000303"
     CDS             complement(54327..54491)
                     /locus_tag="VVR08_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU6074277.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(54658..56253)
                     /locus_tag="VVR08_000304"
     CDS             complement(54658..56253)
                     /locus_tag="VVR08_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074278.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(56265..56675)
                     /locus_tag="VVR08_000305"
     CDS             complement(56265..56675)
                     /locus_tag="VVR08_000305"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6074279.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(56791..57582)
                     /gene="yghU"
                     /locus_tag="VVR08_000306"
     CDS             complement(56791..57582)
                     /gene="yghU"
                     /locus_tag="VVR08_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU6074280.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(57595..60291)
                     /locus_tag="VVR08_000307"
     CDS             complement(57595..60291)
                     /locus_tag="VVR08_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU6074281.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            60595..61779
                     /gene="mntE"
                     /locus_tag="VVR08_000308"
     CDS             60595..61779
                     /gene="mntE"
                     /locus_tag="VVR08_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU6074282.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKTAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(61922..63793)
                     /locus_tag="VVR08_000309"
     CDS             complement(61922..63793)
                     /locus_tag="VVR08_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6074283.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(63790..64974)
                     /locus_tag="VVR08_000310"
     CDS             complement(63790..64974)
                     /locus_tag="VVR08_000310"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU6074284.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKDIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(64986..65753)
                     /locus_tag="VVR08_000311"
     CDS             complement(64986..65753)
                     /locus_tag="VVR08_000311"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU6074285.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESEPEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(66019..66867)
                     /locus_tag="VVR08_000312"
     CDS             complement(66019..66867)
                     /locus_tag="VVR08_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6074286.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(66869..67243)
                     /locus_tag="VVR08_000313"
     CDS             complement(66869..67243)
                     /locus_tag="VVR08_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU6074287.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(67317..68669)
                     /locus_tag="VVR08_000314"
     CDS             complement(67317..68669)
                     /locus_tag="VVR08_000314"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU6074288.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
                     "
     gene            complement(68693..69472)
                     /locus_tag="VVR08_000315"
     CDS             complement(68693..69472)
                     /locus_tag="VVR08_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU6074289.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(69459..70316)
                     /locus_tag="VVR08_000316"
     CDS             complement(69459..70316)
                     /locus_tag="VVR08_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU6074290.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            70452..71417
                     /locus_tag="VVR08_000317"
     CDS             70452..71417
                     /locus_tag="VVR08_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6074291.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(71451..72362)
                     /gene="whiA"
                     /locus_tag="VVR08_000318"
     CDS             complement(71451..72362)
                     /gene="whiA"
                     /locus_tag="VVR08_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU6074292.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(72359..73336)
                     /locus_tag="VVR08_000319"
     CDS             complement(72359..73336)
                     /locus_tag="VVR08_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU6074293.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(73333..74223)
                     /gene="rapZ"
                     /locus_tag="VVR08_000320"
     CDS             complement(73333..74223)
                     /gene="rapZ"
                     /locus_tag="VVR08_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU6074294.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(74275..74655)
                     /locus_tag="VVR08_000321"
     CDS             complement(74275..74655)
                     /locus_tag="VVR08_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU6074295.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(74666..75253)
                     /locus_tag="VVR08_000322"
     CDS             complement(74666..75253)
                     /locus_tag="VVR08_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU6074296.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(75262..76494)
                     /gene="clpX"
                     /locus_tag="VVR08_000323"
     CDS             complement(75262..76494)
                     /gene="clpX"
                     /locus_tag="VVR08_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU6074297.1"
                     /translation="MPTNRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DANSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(76531..76701)
                     /locus_tag="VVR08_000324"
     CDS             complement(76531..76701)
                     /locus_tag="VVR08_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074298.1"
                     /translation="MERSIFGFFTAMLCLVCLLAGAQAFRKKRYGLSVLLWLNAFTNL
                     VNSVHAFYMTLF"
     gene            complement(76701..77207)
                     /locus_tag="VVR08_000325"
     CDS             complement(76701..77207)
                     /locus_tag="VVR08_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU6074299.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWYLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNSEEKIDGVTTFYDVQSVLGWYQAQDKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEEFDLSIFEIVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(77338..77856)
                     /locus_tag="VVR08_000326"
     CDS             complement(77338..77856)
                     /locus_tag="VVR08_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU6074300.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLSELFQKGLDVTDEEGDDVTNGIFADAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(78352..79856)
                     /gene="lytC"
                     /locus_tag="VVR08_000327"
                     /pseudo
     CDS             complement(78352..79856)
                     /gene="lytC"
                     /locus_tag="VVR08_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            complement(79894..80652)
                     /locus_tag="VVR08_000328"
     CDS             complement(79894..80652)
                     /locus_tag="VVR08_000328"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU6074301.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(80750..81427)
                     /locus_tag="VVR08_000329"
     CDS             complement(80750..81427)
                     /locus_tag="VVR08_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU6074302.1"
                     /translation="MTYLDAFKSGALVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            complement(81436..82380)
                     /locus_tag="VVR08_000330"
     CDS             complement(81436..82380)
                     /locus_tag="VVR08_000330"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU6074303.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFLEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(82562..83074)
                     /locus_tag="VVR08_000331"
     CDS             complement(82562..83074)
                     /locus_tag="VVR08_000331"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU6074304.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(83161..83919)
                     /locus_tag="VVR08_000332"
     CDS             complement(83161..83919)
                     /locus_tag="VVR08_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6074305.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            complement(84420..85550)
                     /gene="ugpC"
                     /locus_tag="VVR08_000333"
     CDS             complement(84420..85550)
                     /gene="ugpC"
                     /locus_tag="VVR08_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU6074306.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(85833..85918)
                     /locus_tag="VVR08_000334"
     tRNA            complement(85833..85918)
                     /locus_tag="VVR08_000334"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(85882..85884),aa:Leu,seq:aag)
     gene            complement(86000..86575)
                     /locus_tag="VVR08_000335"
     CDS             complement(86000..86575)
                     /locus_tag="VVR08_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6074307.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            complement(86575..87363)
                     /gene="codY"
                     /locus_tag="VVR08_000336"
     CDS             complement(86575..87363)
                     /gene="codY"
                     /locus_tag="VVR08_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU6074308.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            complement(87627..89201)
                     /locus_tag="VVR08_000337"
     CDS             complement(87627..89201)
                     /locus_tag="VVR08_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6074309.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            complement(89400..90626)
                     /locus_tag="VVR08_000338"
     CDS             complement(89400..90626)
                     /locus_tag="VVR08_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU6074310.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLLFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            90819..92135
                     /locus_tag="VVR08_000339"
     CDS             90819..92135
                     /locus_tag="VVR08_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU6074311.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGNEKKELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFTGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            92234..93577
                     /locus_tag="VVR08_000340"
     CDS             92234..93577
                     /locus_tag="VVR08_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU6074312.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            93577..94359
                     /locus_tag="VVR08_000341"
     CDS             93577..94359
                     /locus_tag="VVR08_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU6074313.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            94485..95567
                     /locus_tag="VVR08_000342"
     CDS             94485..95567
                     /locus_tag="VVR08_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6074314.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            95560..95763
                     /locus_tag="VVR08_000343"
     CDS             95560..95763
                     /locus_tag="VVR08_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074315.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(95890..>96134)
                     /locus_tag="VVR08_000344"
     CDS             complement(95890..>96134)
                     /locus_tag="VVR08_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6074316.1"
                     /translation="ESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLN
                     QLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT        28055 a        21501 c        17831 g        28747 t
ORIGIN      
        1 gttacggcca ccacgtgttt cttgaaggag agagtcgagt tcgaactcct catatttttt
       61 tacatttcgc caaatcattg tttgattaca gtctaaaagt tctataatct ctttataaga
      121 tttgcccata tcagacgaaa tagaacgatt tgaagacgtt tatgatattt agctgtacga
      181 gagtctttta aaagtgtttt gatggtttgg atttcttctt taattgattt catattacta
      241 ttgtataatg ctttttgatt ttagtctagt attatactct tcgaaaatct cttcaaaccg
      301 cgtcagcttc gccttgtcgt atagatgtta ctgacttcgt cagttctatc tacaacctaa
      361 aaacagtgtt ttgagcagtc tgtagctaac tttctatagt aaaatgaaat aagaacaaga
      421 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtaa atgtgtacta
      481 ttctagtttc aatatattat agtttgctct ttgattttca ttgagtatta gttcaatatc
      541 taaaaaaaga accttgccaa gcaagattct tttagtgtct gacttaaata attgttcttc
      601 tgggaactaa atcgaattaa gcttcgattt ctgtaaccat acctgaacca acagtacgtc
      661 caccctcacg gatagagaat gtagtacctt gttctacggc gattgggtga atcaactcaa
      721 cgtcgattgt cacgttatca ccaggcatta ccatttcagt acctgctgga agttcgattg
      781 aacctgtaac gtcagtagta cggaagtaga attgtggacg gtagttgttg aagaatggag
      841 tgtgacgtcc accttcttct ttagtaagga tgtagacttc acctttgaat ttagtgtgtg
      901 ggttgattga acctggttta gcgataactt gtccacgttc gatttcatca cgttgaacac
      961 cacgaagaag gacacctacg ttatctccag caagaccttc gtcaagttgt ttacggaaca
     1021 tttcaacacc agtaacaact gctttttgag tttcttcttt gataccaacg atttcgattt
     1081 cgtcgttgac tttaacgata ccacggtcga tacgtcctga agcaactgta ccacgtccag
     1141 tgattgagaa tacgtcctcg actggaagaa gcaatggttt gtcagtgtca cgttctggtt
     1201 ctgggatata ctcatcaact gtgttcatca attccataac gatgtcttcg tatttagagt
     1261 caccttcaag agctttaagt gctgaacctt ggataactgg aagatcgtca cctgggaagt
     1321 cgtattctga caataggtca cggatttcca tttcaaccaa ttcaagcaat tcttcgtcgt
     1381 caaccaagtc aactttgttc atgaagacga taaggtgttt aacaccaacc tgacgtgaaa
     1441 gaaggatgtg ctcacgagtt tgtggcattg gtccgtcagt tgaagctact acaaggatag
     1501 ctccgtccat ttgagcagca ccagtgatca tgtttttaac gtagtccgcg tgtcctggag
     1561 cgtcgatgtg agcgtagtga cgtttttcag tttcgtactc aacgtgcgca gtgttgatag
     1621 tgataccgcg ttcgcgttct tctggagcag catcgataga cgcatagtct ttaggttggt
     1681 taactgatga aggcaagcga cgtgccaaaa cagttgtgat agctgcagtt agggtagttt
     1741 taccgtggtc aacgtgtccg atagtaccaa tgttaacgtg tggtttacta cgatcgtatt
     1801 tttcttttgc catttgagta aaagcctcca ataaaatata ttttatagat agacagtagg
     1861 caatacagtc taactttcct tactatttta tcaaatttca gctaaattgc aagtgtttta
     1921 caacgttttt gtgaattatt cttgataaaa atttaactaa ctaatagaaa gtactaaata
     1981 gacttatcct tcaaggagtt ttcagcatta tccatccact cacttgctga aaatgtaaac
     2041 agtctctggt ttatatagta aaatgaaaca agaatagggc aaatcgatca ggacagtcaa
     2101 atcgatttct aacaatgttt tagaagttga ggtgtactat tctagtttca atctactata
     2161 caacctcaaa actgtgtttt gaacaacctg cggctagctt cttagtttgc cctttgattt
     2221 tcattgagta taaaattgca gataaaacga taacaatcat aggactcagc agagtcaatg
     2281 taggtcgaag aatagccctc ctaatcgctt attttatagc aaaatgaaat aaaaactgaa
     2341 cattttgttg aggaaggtaa atcaattcct cacaatgttt gagaaagaag ggaggactat
     2401 tccaacttca acccactata aagcagactt acaagatagg gaacccatct ccgataatat
     2461 atagtagaat gaaaactgca caatttgatt ggagaattca aaccaatttc taacaatgtt
     2521 ttagaaacaa gggtctatta tttcaactgc aacctactat agcccattga agctggaata
     2581 gcccactgag acttctaaac cactgctgga gaggagtttg tttagagttt ctttcatttc
     2641 cctaaaaaat caaaaagaga gaaccagtct gatcctctct tacttataga tggtgctcac
     2701 tcaaatgtta aaggagctat ttcttagaga taaaggaatt tgaatacagc tactgccgca
     2761 attgctgctg cgataggtgc tactactggt acccaagaat accaccattt tgaatcgcct
     2821 ttatgctcac caagaactga ttttggaagg aaagcatgaa ggagacgtgg tcccaagtca
     2881 cgggctgggt tcaaggcagg tcctgtaggt cctccaagtg atgttaccaa agccataacg
     2941 aggaatccaa gtgccaagtg agccacagaa agtcctgaag cagtgtgtgg agccacctgt
     3001 gctttaatag ccaagtcaga aaaatcaact gtttgtcctg cttctattgc cttttgtttc
     3061 atgaattgaa gcacttcagc accaaagaag tttttagtca aaccaagagc tgcaaagaac
     3121 aaaacaaatg aaccaacaaa ctcattaatc aaaccattga cagttgctgc atagcgactt
     3181 tcttttgtac catggtcaat acttgaaata gttgagaaag ttcccaagat gttatttggt
     3241 ttttcagttt tcaagtagaa tggacggtat gttgccacaa ctaaggcttg gccaaagata
     3301 gcccccaaga cttgcgcgat aatgtaaggt accacttgtg cccaagggaa aagaccgcta
     3361 actgcaagcc ctagagtgaa agcagggttg atgtgattcc cagatacgtt accaaacatc
     3421 aaggctggga tcataacccc cataccataa ccaacagcga tgacgatcca gccactttgg
     3481 tgacctttcg tacctttaag ttcaacgttg gcaactgcac cattcccaag aatgatcaaa
     3541 atggcagttc ccaaaaattc agtggcatac ttcagtgccc atgtgaaatc catttgctag
     3601 attctcctta aaatttttta gatattcctt attttatcaa tttttaccct atttagcaac
     3661 tgatttctgg aaatattttt aaaaaaatag gattcatagt ttcccagttc aacgtacttg
     3721 taagcgtttt tattcttcac gaaagacctc attctcaaaa ccaggaaaaa gcccacatct
     3781 gtgatctttt ccttgttcct agattctaaa atctattatt tttcatcttc tttttcttga
     3841 agaatcctaa tcctagacca gctaacaagg tcatgatacc agcactagcc aaggtagcat
     3901 tagcttctgt acctgtgttt ggcaattcct ctctcttacc tgtctcataa gtcggaactt
     3961 ctgggtctgg attcactgga gtttcagttt ttggagtacc tgggtctgga gttggtttat
     4021 ctggtgttga taaacggtca taccttaccg ttatttcttt atcactagag tctgacgtaa
     4081 cttcttgtga ttcaactgtt ggaatatctg gatctttgta cttgtcaatc ttaccagata
     4141 caacctcgtc ccagtttcct gttgtccatt caccgtaggt tacaactccc gtgaccttgt
     4201 tctcagtttt tgtacggctt aaggttacag gttgaacaac atcttctttt acattttggt
     4261 tcgtaacttt atcaacgtaa tgaatgatac gcgttatagt cttcgtctca gtagaggttg
     4321 ctgttttggg aaccactgtt tcctcaacat tctcacggta gtaatagtca actgttgcac
     4381 cgtcttctgg tacgcatttg caggagttgc taccaaggtg tatgttgttt tccttgtgat
     4441 aactcggtct tctttgtcct cagttgttgt tttcccttca atagtttttg attctgtggt
     4501 atactcagaa cctatcgcta aatcagcttt tataacagac tctgccaact tctcttggct
     4561 accttcttta tagtaattgg ctgttactgt agcagtggtt ggcgcttcgc tttctctata
     4621 aactaaggtc actgttctac cttcgcttac aatattccca gttaaacttg cagaatttgt
     4681 atctgcttct ttaaaagtat aatattttcc gtcagtagta gtcatgctac tgagtttttt
     4741 atctgtgaca ttgtagctgg taccaatcag ttgtttttta ttggtaatgt aggttccgtc
     4801 actttctttt tctccaattc cagtatcatt tttcaatgat agcaaacgcc cttgttcatc
     4861 aacatagcga actttcacat tttctgagat tagttctgcc aattctgagg tttttttctt
     4921 tttcttgatt tcttcggtta ttttcccttt ctcttcttcg ggaatattta gttttggaat
     4981 gattttttca acaacggttc gtgatggttc cacagtatct tggatgactg aaaagtcagc
     5041 tagaattggg agattatact gaacacggtg actttgagtg tttactccta ctctttcatt
     5101 attctctgaa aatacttgta cggtataaga aacaacatct tttcctaata gaacatcccc
     5161 agtagagaaa tagccgcctt ttcctagttt gctatctcca gagtccactt ctttcctaat
     5221 cttatcagat agttttttac cagtcagtac attcgttcgc acaatccctt tgtctacccc
     5281 tacaaagtgg gagaactttt tgaactcttc agaaccagat ctagcccaac cattattaag
     5341 ggcatttgct tttgtatttg tattctctct caaaggtttg gcgattagaa ttatattcat
     5401 cggcacttag agttgctgct atatctgact cttgaatacc aacttcctta ctaccatttc
     5461 tagcggcagt atatgtgtat ttatctgttt ctacttctag ctgattatcc ttaacatgat
     5521 aggtaatttt ctcctggtat aagagtcttc agtagtttat atgctctgtc atcatcttta
     5581 gctttagaag cagctgagtt tagccaagtt ggggtattag gagtatcttt atcagcctgt
     5641 ttcaagacat tattcaagtc atttgctaac ctattggttg tcctcactgt gaaagttttc
     5701 ttccagtctg aatcactttt attagactta gatatgctca tgaaatcctg gtcaacattc
     5761 aacacaatat cgccttgttt tttagcatct tccgttgctt ctgcttcaaa ttgatcatgg
     5821 agtttttgtt gctccggtgt atagtttttt tatttacacg atttaatgta ctatttttta
     5881 ttttagtatt aagaactcca ttaatacgat ttttaaattc tgcttcaaaa aatcccttaa
     5941 tttgttggtg cgcaagttca acattcaaac ctttcttata caagtcttca ttctgataca
     6001 agtcttcatt ctgaacgatt tcggctacac ggtgaatggt ttgatcgtat accgtcttct
     6061 cttaaccagc agtatcctta gttttaatga ctactcgata ggttccttta gaaccgttat
     6121 agtcatctag ttttaaaaaa gcattccaaa cattcaaaaa tagttggaac ttcccttaat
     6181 aaatccgtca ctttcttttt caagatagcc caagcttgct caataggatt caaatccggt
     6241 gaataaggtg gtagaggtaa gaaaaagtgt ttatcttgga tgcagagttc atccaaaatg
     6301 ttcttgggat gaaaactagc attgcccatg acaataacat gaggtgtctt caaagcaggt
     6361 aggagttgcg ttttgaacca ctccacaaag aaatcgcttg tcatgctttt cttgtaaatc
     6421 atgggagcta taaactctcc gtctacttgt cctgcaacaa ttgaagttcg ctcaaaacga
     6481 cgtccgctaa tcttttcata gactttctcc cctctaggag cccctgcata aggacgatag
     6541 aggtagcggt cgattcctgt ttcatcaata tatacgattg gtaaatcttt taggttatcc
     6601 aaaatatcaa gaaactcagc gactttctct gactcttgtt ccttaaagat cgtcatcttt
     6661 ttttaaagtg accttaatct gctttaaagc tgcccatact gaaggaacag cacaatcaaa
     6721 atgtgccgca atttcccgta aaaaagcatc tggatgagcc tctacaaagg ctttcaattc
     6781 ttctaaaggg atcttacgct ttttgacgac tcgctttttc cgctctaagt tcctttgttc
     6841 acgtctttct tttcccacgt gaagagagtt ctgacgccaa caccaaaaaa ctttggccgc
     6901 ctcgacatgt ctgtgccctc ctttgatgga atctaatgct ccttgtttaa aatcagtatt
     6961 atatgccata gctttattag accatgctta ttttaaacta agcaactata tcaatgtttt
     7021 gttatgagaa gacttacttt ttttactgaa attgaatttt tcctagcctc aacatcatat
     7081 aaccccaaaa ttcaatctga cctggtttga agagatgttc gaagcagata aggttttact
     7141 aaaactaaaa aaaatgatat aatcaaactg attaaatgtt ttaaaaataa aggagaattt
     7201 gaatgtctta ccaagaaaat taccagaaat gggttgattt tgtggagctt cctgactacc
     7261 ttcgtcaaga tttggaaaat atggacgaaa aaactaagga agatgccttc tatacaaatc
     7321 ttgaatttgg tactgcaggt atgcgtggct tggttggtgc tggtacaaac cgtatcaaca
     7381 tctacgttgt tcgccaagct actgaaggat tggctcgttt gattgagtca aaaggtggaa
     7441 acgagaaaga acgcggtgta gcaattgcct acgatagccg tcacttctca cctgagtttg
     7501 cctttgaatc tgcggcagtt cttgctaaac acggcatcaa atcttacgta tttgaaagcc
     7561 ttcgtccgac tccagaacta tcatttgcag ttcgtcatct caactgtttc gcaggtatca
     7621 tggtcacagc cagccacaac cctgctccat ttaacggtta caaggtttac ggtgaagacg
     7681 gtggacaaat gcctccacac gatgcggacg ctttgactac ttatatccgt gcaatcgaaa
     7741 acccatttgc agttgaagtt gctgatgtgg aaactgaaaa agcttctggc ttgattgaag
     7801 ttatcggcga agctgttgac gtagaatacc ttaaagaggt taaggacgta aacatcaacc
     7861 cagccttgat tgaagaattt ggtaaagaca tgaagattgt ctacacacca cttcatggta
     7921 ctggtgaaat gttggctcgt cgtgctcttg cccaagcagg atttgactct gttcaagttg
     7981 ttgaagcgca agcaactgct gacccagact tctcaactgt aacatctcca aacccagaaa
     8041 gccaagcagc ctttgccctt gctgaagaac ttggtcgtca agttggtgca gatgttcttg
     8101 tcgcaactga cccagacgct gaccgtgttg gtgttgaagt tcttcaaaaa gatggtagct
     8161 acctcaacct ttcaggtaac caaatcggtg ctatcatggc taaatacatc ttggaagctc
     8221 acaaaaacgc tggaactctt cctgaaaatg ccgctctctg caaatctatc gtttcaactg
     8281 acttggtaac gaagattgct gaaagctacg gcgcaactat gttcaacgtc ttgacaggtt
     8341 tcaaatttat cgctgaaaaa atccaagaat tcgaagaaaa acacaaccac acttacatga
     8401 tgggatttga agaaagcttc ggttacttga ttaaaccatt tgtacgtgat aaagatgcca
     8461 tccaagccgt tcttgtcgtt gctgaacttg ctgcctacta ccgttctcgt ggtttgacac
     8521 ttgctgacgg tatcgaagaa atctataaag aatatggcta ctacgcagaa aaaacaatct
     8581 ctgttactct ttcaggtgtc gatggtgctg aacaaatcaa agcgattatg gctaaattcc
     8641 gcaacaatgc tccaacagaa tggaacgcaa cagctatcac tgtcgtagaa gacttcaagg
     8701 cacaaactgc tactgttgct gacggtactg ttacaaactt gacaactcct ccaagtgatg
     8761 tgttgaaata cacacttgct gacggttcat ggattgccgt tcgcccttca ggtacagaac
     8821 caaaaatcaa gttctacatt gcagttgtag gggaaaccaa cgaagaatca caagctaaga
     8881 ttgctaacat cgaagcagaa atcaatgcat ttgtaaaata aagacctata aaagatgaga
     8941 ccaaccaacc tcatcttttt tcgtatcaaa tctaagcaat tttagaaact ttatggcata
     9001 ctagacttat caatgaaagc gaggtaatct catggaacaa tttttagata acatcaaaga
     9061 ccttgaagtc actacagttg tgcgtgcgca agaagctctt gataaaaaag aaactgcaac
     9121 cttctttatc ggtcgcaaaa cttgccctta ctgccgtaaa tttgcaggta cattgtcagg
     9181 tgtcgtagct gaaaccaaag ctcacattta cttcatcaat agtgaagaac caagccaact
     9241 caatgatttg caagcattcc gctcacgcta tggaatccca actgtaccag gttttgttca
     9301 tattacagat ggacaaatca acgtccgttg cgactcttca atgtcagcac aagaaatcaa
     9361 agatttcgca ggattgtaaa aaatcagcta acaagtctta aaatcacaaa aacgcataat
     9421 gtaaggtgca aaaaccttga tattatgcgt tttattgttc ctaaaacagt tacatcagca
     9481 tttcattaca gaacatttta attttggaag tcaaatcaat ttttaacaat gttttagaaa
     9541 tcacagtggg ctattccata ttcaattatc cagattcaat cgctattatc gttttcctag
     9601 attacaaaaa aactgcgttt tgctaatcaa aacgcagtct cagccactat tttatcttac
     9661 tgtccttctt ttacttcttt ggttgctaca tcttctccaa accatttttg gctgatttct
     9721 tggaacttgc cgtccttgta aagactagaa aaagcttcat ttatcttctt aaccaaggtt
     9781 gtatcttcct tacgggctcc aaccgcaaaa gcttctgttt ctagtccaac tgtaaagaca
     9841 ttataatcgt ttaaaacacc ttctgcttct aaataatagt ttgcatagac acggtcaatc
     9901 aatagaccat caattcgatc gtttttcaaa tcaatcaagg cttcattaaa ggtttggtat
     9961 tgattcgctt ccttattagc gacaatattc ttcaaaattt ctggatttgc ttcaaagtcc
    10021 gcataaccag atgaaccagc ttgagctcct aatgtctttc cagtcatatc ctttgcagtc
    10081 gtgataccag atgatttctt cgtaaccaat acctgctcat tcttcatata tgagttactg
    10141 aaagccacct tttcacggcg ttcgtctgta gcggaatagc cattccaaat cagatcaatc
    10201 gttccttttg tcaattcagc ttctttcaaa tcccaatcaa tcggttgcca atttaccgtg
    10261 attccgtatt tttcaaaaac agctgtagct aaatcaatat caaatcctgc ataagaacca
    10321 tctttctgag caaatcccat tggaacaaaa gtactatcaa atccaatagt aatagacttg
    10381 ttagactggt actttgacca attatctcca ctagtttcgc tagaattttt cccacaagct
    10441 actaagaaca aagcagtcat cagactgact aatacaagca tccatttttt catccatttt
    10501 tcctcctatt taggttctac tttcaataat acatctgcga tattttcagc aaactgcaaa
    10561 tcatgggtaa ccacaatctg ggtcatccca agttccctat tttgcaagat tagcttctcc
    10621 acttccaaac gtaattctgg atccagggca gaagttggtt catcgtagcc aatgatttct
    10681 gggtcaatca tcatagcacg cgccaaagcc acccgctgct tttgcccacc agatagtgag
    10741 aaaggatagg cctctgcgtg tcctcctagt cctaactgtt ccaagagtcc actcgccttc
    10801 ttctcagcct cttcctgctt cattcccatg gtcttcacag gcgataaggt caaattgtcc
    10861 agaactgata aatgagggaa cagttgaaaa tcttggaata caaatcccag tagattgcgc
    10921 ttctgcaatt catccagctc taaaggttgt ccattataaa agatttgccc tgaatcaatg
    10981 gtttcaagac ctgcaagcat acgtaaaaga gttgtcttac ctccaccaga aggtccaacg
    11041 atagccagga tttgcttttc aggaatactt agactgaaat tagacaggat ttgtttgtct
    11101 ccaaagactt tattgatatt tcgtaattct aacatggcag cctcctatct ataataacta
    11161 tacttcttct caactttttt ggaaataatt gtcacaatcc caatcaaaat caaataaatg
    11221 gctcctgcca agaacatagg aactagacta gcatcgcggt tagcagctgt tcgactagcc
    11281 aagataaggt ctgaaattcc gagagcatag accaaagaag tatccttgac caaactcata
    11341 acttcattaa agacactagg aagaacgatc ttggtcactt ggggcaagat aatatagcgc
    11401 actctgtcaa aagggctaaa cttcaagacc ttggcggcct catactgtcc tcttggaata
    11461 gtgtcaattc ccccacggaa aatttctgca aagtaagctg catagttgag aacaaaggca
    11521 ataatagctg caggaaggcg gtctaaacga atcccaatac ttgggagcac ataatagata
    11581 aaaatcagtt gcaagagtaa gggggttcct cgcataaccc agatgtaaat gttaatcaga
    11641 taatggaggg gcttccaatg gacttgcaag gcaaaggcaa tcaaaacgcc caagggaatc
    11701 gaaaatagca agaccagtgc aaagacctgt acagtcgtgc tcgcaccatt cagtaaactc
    11761 ggtaatatct caaataaata agacatactg cacctcctaa aagtaattgt tcctattata
    11821 gcatgaataa acaagattac caagtatttt tgtaaaaaga ttctaccata tacaaataaa
    11881 aaccgtagct atcaaaagag ataaactaca gttctatatg tttaaacatt cttacaatct
    11941 ctcaaacagt tcttgcattt gcacatcatc tggaaccagt tttaagtaag tgtgagcatg
    12001 gacttttgct tcttcaaaat gtcccaattc acgcaagaga tagatatagt gttccagaaa
    12061 ttctggattg tccttcaaat ctcctgtcaa ctcttgataa tgctcataag cagtatccaa
    12121 atcgtccatt tcttgataag aacgagcaat catccacttg gtcaaaagat tttctggctc
    12181 ctcactctgc aagtctagaa tatcctcata acgctcctgc tccagataaa tagtggctaa
    12241 acgaagcaag atttcttctg tatcctcagc gtcttctttt gcagtaagga gataattttc
    12301 tgcaccacta gcatcatgta attcataaga aaattgtgaa gcagctagca agaggcgagt
    12361 ttcaaaggga tttttctcta atccttgctt agcgatacgc agggcttctt gaacttgatg
    12421 ttccttatgt aaagcctgac tgtacccata ctcatagcct tcaaagtcag gagaaatggt
    12481 atcaagctgc ttaaagtaga gggtggcttt ttgatattct tcttgatcaa aataaagact
    12541 ggccaactca aaagctgtta agtcatcgta ttctaactcc agggcttttt ctaaaaactc
    12601 agtagccgtt tcaaatttcc ctaactgagc ataggcaaag ccaattcgtt gataggtgga
    12661 aatgcccgtt tgctcataaa tcgagcgatt atctaactgg gcataggctt gaatagccgc
    12721 ttggtaattt tccaactcac tatccaactc tgccaaaccc aatatcaaga gagaatcctc
    12781 tgagtaggtc aaggcctcca ataatttctc acgtgccaca tctgtcaaac cttccagctg
    12841 gtaaaggtct gccttcagag ccaaagacga gacataccag tcactgtcag cttggatttc
    12901 ctcaagatag gtaaaggctt cttctatttg accatcctcg ctagcaattg cagctagatt
    12961 aagatgaacc tctggaaaat cctctacaat tttcaggtaa atttccttgg cctgaggata
    13021 gaaaccaatc ccttcaagat aagttgccaa ctcatacaga agatcacttg aatcattttc
    13081 taaagctttg gcgaaataat gctcagcctt agttaaatct tgctcctcca aagcctgtaa
    13141 catctgttga ctattgttca ctcttgactt cctcaccctc taattcatat agaccactga
    13201 ctaccttata ccattcgaaa atggctgaaa tgacaacctt agcagaggca taaaccggaa
    13261 taccaagtaa aactccccag ataccaaaca tagatcctga agttaacaaa acaaagagaa
    13321 cattaatagg gtggatgttt aattgacttc ccaaaatcaa tggagagaca aaacggcctt
    13381 caatagtttg ttctacgata aagacaatca ctactttcaa aagcatgact ggaccagcaa
    13441 tcaaacccaa tactagagca ggaagcatgg ctagaaagct accaagataa gggaccagat
    13501 ttaaaatacc agcagtaacc cccagcgtaa ccgcatagcg tagaccaata atcttgaaga
    13561 agatgataaa cattactgct acaataatag ccactgtcac ttgccctcga acatagttgg
    13621 acaactgttg attcacatct gataaaactt gtccaacagg ttccttcaat tttcttggaa
    13681 tgaattgggt caaatagtta cgcaagcctt tcccatcacg caagagataa aagagcatga
    13741 aaggaacgat aatcaaggca acaatcactt gagaagctcc gctaataaag gcactcaccc
    13801 agttgactgc ctgagatgaa accttacttg ccaaaactgt agcctggcta gaaaaattgg
    13861 tcaaaacttg ctctaattga ggtctgaaat catctggcag gtgctgggct accaatccat
    13921 taacaatcct atctatatct tctaagtaaa caggaacgtt tcttgcaaag gtcaaaacct
    13981 gacgttgcag atttggaatg gcgactgcca agccccaaat gataaagaga gcgatgataa
    14041 caaagacaat agtgatagct ataacacgat taaccttatg cttctccatc caatcaacaa
    14101 taggattcaa caaataatat aacaaaccag ataaaatgac tggcaacatc acaactgcta
    14161 aaaagtctaa aacaggtgaa aatagaaaac taatcttact taaaataaaa agattcagtc
    14221 ccaataataa ggttactaaa aataccgtaa ttgccttgtt atctaaaaac cacttgaaaa
    14281 accaagatag gctaaaatgt ttctcttttt gctccataaa tacttccttt ctattgttct
    14341 ctcattatac catttttgaa acaaaataac tcttttttaa agtgcttaca tctaattgga
    14401 tgtctttaat ttgcttgttt ttgtgatata atagtcttat ctttacacag aggtatagta
    14461 atgaaagaaa ctgtttattt tggaacttat acacgtcgta cttctcaagg gatttacaag
    14521 gcagactttg atacagaaac tggtcagctt tcaaatctag aactttttgc agctgagcca
    14581 agtccaacct accttgcctt tgaccagcac caacatttat acactgttgg tagccaagac
    14641 gataaggggg gaattgcagc ctatcaaact gacgggactg tgttaaatca tgttgttgaa
    14701 gaaggagctc cccactgtta tgttgctgtc gatgaaaagc gtgatttggt ttacgcagcc
    14761 aactatcaca agggacaagt ccttgtttat aaacgccagg aagatggtag tcttctactt
    14821 agtgatatgg atcaacacag tggccaaggt ccacatgaaa atcaagcttc cccccatgtt
    14881 cactatacag atttaacacc tgaccactat ctagtgacct gcgacttggg aactgaccaa
    14941 gtcatcacct atgacctcga tcaagaagga aaattatcta agctctatac ctatcacagc
    15001 aagccaggag caggctcacg ccatatcatt ttccataacc actataaaat cgcttatctc
    15061 atttgtgaac tcaatagtac tatcgaagtt ttaatctacg atggcgttgg cgaatttgta
    15121 cgtatgcagg ttatttcaac tttaccagaa gcttacgaag gctttaatgg aaccgctgct
    15181 attcatctct ctaaagacgg taaatacctc tacgcttcta accgtggcca tgattctatc
    15241 gcagtatata ccatccttgc ggacggtagc ttagagttat tagaaatcgt tccaacgcat
    15301 ggtcagactc cacgtgattt tgatttgaca cccgaccaaa aatttctcat tgttgtccat
    15361 caagactctg acaatgcaac tgtctttaaa cgtaattgtg acaatggtcg tctagcagaa
    15421 ctctccaacg aattccatgt tcccgaagca gtctgcatcc gttttgctcc ttaaaacacc
    15481 ataaaaaatg aacttggtat tttcaagttc attttttctt atagtctatt tccgacatta
    15541 atacggttaa tggcacgttg caaagcaatc ttagcacgac gttcttggtc aatcaaatgt
    15601 ttgtcttgtg cttcttcaat tgcacgttct gcacgaagtt tggcacgttc tgcacggcta
    15661 atatcgatat cacgagcacg ttctgcagag tcagcgacga ttgtgatcat atcattggca
    15721 atttcaataa cgccaccgtt tactgcaatc cagttcacgt gatctttatc atcgatacgt
    15781 tttaccttta cttcatcaac tgctaaaacc gcaatcatat tttcatgtcg tggcaagatc
    15841 cccatctcac catccagagt tcgaaccgat acatagctgg catggtgatc atagacgaga
    15901 ccatctggtg tcacgatctg gacagttaac tgagccatag gtcacctctt aaaatcccat
    15961 tttttcagct tttgcaatca catcttcgat agaacctaca ccacggaagg catcttctgg
    16021 caagtggtcg tatttaccat caaggatttc cttaaagcca cgtacagttt cagcaactgg
    16081 aacataagaa cctggctgac cagtaaattg ttccgcaacg ttgaagtttt gtgacaagaa
    16141 gaactggata cgacgggcgc gagcaaccaa ggtcttttct tcatcagaaa gctcatccat
    16201 accaaggata gcaatgatat cttgcaattc atggtaacgt tgaaggacac gttttacttc
    16261 agcagcaact gcatagtgct cttctccaac gatttcaggt gccaaggcac gtgagcttga
    16321 agcaagtggg tcaacggctg ggtagatacc caattgtacc aacttacgtt ccaagtttgt
    16381 tgttgaatcc aagtgagcga aggctgttgc tggcgctggg tcagtatagt catccgctgg
    16441 cacatagata gcctggatag aggttacaga acccttcttg gttgatgtga tacgttcttg
    16501 caattgaccc atttccgtag caagtgttgg ttggtaacca acggctgatg gcatacgacc
    16561 caaaagggca gatacttctg aaccagcctg agtgaaacgg aagatattat cgataaagag
    16621 aagcacgtct tggccttcca catcacggaa gtattcagcg attgtcaaac cagtaagggc
    16681 aacacgcata cgtgctcctg gtggctcatt catctgacca aagaccatgg ctgttttctc
    16741 gataacgcct gattctttca tttcccagta aaggtcattc ccctcacgag tacgttcccc
    16801 aacaccagta aatactgaaa taccaccgtg ctcttgggca atgttgtgaa tcaattcttg
    16861 gattaagacg gttttaccaa ctccggcacc accgaaaagt ccaactttac cacctttaag
    16921 gtaaggggca agaaggtcaa taaccttgat ccctgtttca aggatttcag aagaggtaga
    16981 caactcatca aaagttggag cttttttatg aattggctga cgctctgcgt cttctgtaaa
    17041 aggagcttcc aaatcaatgg tatctcccaa aacgttgaag acacgtccca aagtttcttt
    17101 acctactggt acagagattg gacgacctgt gtccaatact tccattccac gagtcaaccc
    17161 atctgttgat tccatggcga tagtacgaac cataccatct cctaactcca aggctacttc
    17221 aaggacgatt tttgtttttc tttcgtcatt tttgtagacg acaagtgcat tgttaatctc
    17281 aggaagtttt tcccctgctg caaacaaaac gtctacaacg ggaccgataa cctgagcaat
    17341 tttacctgaa ctcatctcct tctcctattc tatataagat actgtcggtt cctagctcaa
    17401 ctaggtccta agttcatttt catacgagct ggactagagc ctattctaag gcactagcac
    17461 ctgctacgat ttctgtaatt tcttgtgtaa tcgccgcctg tctggcacgg ttatactgaa
    17521 ttgtcaaatc attgatgact ttcttagcat tatctgtcgc tgtttgcatg gctgtcatac
    17581 ccgcagcatt ctcagctgtc ttggcatcga taatggcacc gtaaatcata ctttctgcaa
    17641 actgaggcaa caactgctcc agaatttctt ctcggctggt ttccaattca aaagtcaagc
    17701 tgtactcttc atccgcttca tttggatcca agtcaacaat cggaagcatt tgttccacac
    17761 gcatttgact ggttagcgta ttgacatggt ggttgtagca aacataaagc tcatcaaaga
    17821 gttcattttg gtacatttca acagtttttg aaataatctt acgaacttga tcaaagctag
    17881 gttggtctgc caagccacgt aattcataaa gtggttgaat accgcgagcc ttaaagaaat
    17941 cagctcccat cccaccgata cagatcattt caaaaccttt accgtctggg tggtattctt
    18001 ctttcaactc cataacagct ttcaaaatag aggaattata acctccaacc aaaccgcggt
    18061 ctgaagtgat aacgatatag cctgtcttct tcacagaacg gctaatcaac atcggattag
    18121 ttgaagcacc agctccatta ccatgaagga tatctgtcaa aagtttacgc actttctgag
    18181 cgtaaacttg gaagttgcga gcagcttctt cagaacgacc tagcttagca gccgatacca
    18241 tttgcatggc attagtgatt tgactcgtat tttttgttga ggcgattttt gttttaatat
    18301 catttagaga tactgccatc tgacacctct attcttattg gaagctagat tgattgagaa
    18361 actctgtaat cgcagcatcc aagactgctt cttctggcaa gtcttttgta tcacgaatgg
    18421 tttccaaaat ctctggatgt tgagcatcaa agaaggtatg gaactcttcc tcgaaacgaa
    18481 caatatcatc tactggaaca gtatccaaga aaccatgtgt caaagcataa agaatggtta
    18541 cttgtttctc aacaggtaat ggtttgtgaa caggttgttt caagacctca acggtacgac
    18601 gtccacggtt caacttagcc tgtgttgctg cgtccaagtc agaaccaaac ttagtaaagg
    18661 cttccaactc acggtatgaa gcaaggtcga tacgaagtgt accagcaacc ttcttcatgg
    18721 ctttgatttg tgcagaacca cctacacgag atacagatga acccgcatcg atggctggac
    18781 gaatacctgc attgaagagg ccatcgccaa ggaagatttg tccatcagtg atagaaatca
    18841 cgttggttgc gatataggct gagatatctc ctgcttgtgt ctcgataaat ggtagggctg
    18901 taattgatcc accaccaagt tcatcagaaa ctttagctga gcgctcaagc aaacggctgt
    18961 ggagatagaa aacatcccct gggaaggctt cacgacctgg aggacgacga agcaagagcg
    19021 atagttcacg ataagctacc gcttgttttg atagatcatc gtatacaatc aaaacatgct
    19081 taccttgata cataaattct tccgccatag caaccccagt ataaggagct aggaagagca
    19141 atggagatgg ttgtgaagca gaggctgtca caacgattgt gtagtccaag gcaccgtact
    19201 gacgaagtgt ttctacttgc gtacgaactg ttgattcttt ttgtccaatc gcgacgtaga
    19261 tacagatcat atcttgatct ttttggttca agattgtatc aatcgcaatg gttgttttcc
    19321 ctgtctgacg gtcaccgata atcaactcac gttgaccacg accaatcggt acaagggcgt
    19381 caatagcttt caaaccagtt tgcaatggtt ctgaaacaga cttacgttgc ataacaccag
    19441 gagctggtgc ttctactgga cgagttttat cagtgtggat ttctccaaga ccgtcaactg
    19501 gacgaccaag cggatccaca acacgaccaa tcagactttc acctacaggg acttccatga
    19561 ttttccctgt acggcggatt gtatcgcctt cacggatatc tgtaaagtca cctaggatga
    19621 taataccaac gtctgttgac tccaagtttt gagccatacc ataagagccg ttttcaaaat
    19681 tcaacaactc tccactcatg acattttcaa ggccatgagc acgcgcgata ccgtccccga
    19741 tataggttac aacacctgtt tcagtcacat caaaattggg tttgaaattt tcaatttgtt
    19801 gcttaattaa agcgctgatt tcttgtgcgt taattgccaa aagaacacca ctttctattt
    19861 caaattttct ttaacaactt taagttgttg tttaatactc acatcaattg tcttgtgatt
    19921 ggcaaaaatg acaaaaccac caatgagact ttcatcgatt tgttctttta cactccttac
    19981 tttcagagac atttttttct caatcaaagg gagcaaacga gtcttctgtt catcagttag
    20041 aggatgagca gacgtaatcg tcacttcaaa tcgatttgtt tctttttcaa gtcggttcaa
    20101 gcaatctaca agcacatcat aaaaaagatt tgctctgtga ttgtaggcca gaacctggat
    20161 aaagttttgt aataaaggcg acacagaatc ttggaaaaaa gcaattgttt tttccttatc
    20221 cgactcgtct actgccactt gttttaaaaa agaaggcaga cctgtttttt caacaacttg
    20281 cttgatttga gtcaagtctg aaaagatacg gtcttcttct cctttttcaa gtaccaattg
    20341 gacaaaaggc atgctgtatt tttcaattac ctttactgtt ttcttgtcca ttaagcttct
    20401 cctagctgat cgatatactg atcaatgagt gctttatggg catgactgtc aaggttttgt
    20461 gagatgattt taccagctaa gctgatggtc aaatctgcga cctcaccctt aacactctgt
    20521 aaagcttcta ctttattttg agcaatttct tgattggctt tttcttttaa gtgtcctgct
    20581 tctagtttag catctgctaa gatattagcc ttactttgct cagctgtttc ctttgcattt
    20641 tcaatgattg tcttagcttc tttacggcta ccagccaatt catcttcgcg tttttgagcc
    20701 aatacttctg ctttttgacg ggcttcttca gctctatcaa tatctgaagc aattttttca
    20761 gctctttctt cgaaaatgcc tgtaatatta gaccatgcaa attttttaat caagactagc
    20821 aaaagaataa aagagccagt gattaaaata aaattaccaa ttaattcacc tactgttacg
    20881 tgcatcagtt actcctttct attcctcttc aatattaatc ttattcccta aatacacaga
    20941 tgtcaaaaga gtaaaaacat aagcttggat gcaggaaata aagacagaaa atgcagtcca
    21001 agccaaatta gctccaaagg ctactggata ccaataaata gcttggtggg aaagaagaag
    21061 taacaaactc gtcatgacct ctcctgcaaa gatattccca aaaatccgca aagccaaaga
    21121 taagaagttt gtaaattctt ccaagatatt catcggtatg acaaaaacag gactcataaa
    21181 agattttata ctttttttaa atccacgacg acgaacgctt tctatatgtg tcaacaaaat
    21241 gacaagaaaa gataaggtta agtcatactg taaattagcg gttggcgaac tccaccagtt
    21301 agtcccatcg atcgtttgaa gctttgtcat taagccaagg ttattggcaa tcaccatgaa
    21361 aaggaataaa caaaggaaaa agagtgagta atctttcatg tagcgcgaac caatgttagg
    21421 ttctgtaaat ccaataacaa agtcatagac atactcaagt atattttgct ttcctttggg
    21481 tttcaaggtc atattgcggc ttgcccaata aataaagaca aaaataactc ccacaatcaa
    21541 caaagtcatg gctaacatag tcagattgaa gataacagga ccaatagaga tgattggatt
    21601 aatactttct tccatctaaa atcctccctt ttcttctcgt tccatgtatt tatttgataa
    21661 taaatgagaa gacaagagtt acaaagaaag ttccttcaat aaaggcaaca cctaaaaaca
    21721 tcaaactacg aaactcagaa agcatatctg gttggcgtgc tactgattta aacagtccat
    21781 tcatcaataa accttcaccg acagatacgc ccatacaggc aatacataag cctaaaaatg
    21841 ttaaattcat aacaaattct cctttaaaat aaaatttact tacttagtgt agtcctaaaa
    21901 tttaaatttg tcaactttta accgctattg gaagcgttta ataaaaatta tttccatttt
    21961 gctaaatttc aagttcaagt tagccatcca gaagtcttct ctgggtgact tgtagtccaa
    22021 gcatttttta ggatagttgt taatccactt ttcgatgaat gcgacttctt tgggagtcat
    22081 tttcttggtt cccttaggta actatctacg aatgagcctg ttgtgattct cattagttcc
    22141 cctttcccaa gaggcatagg ggtgcgcata atagatgtgc tcctcagaaa atatatcaaa
    22201 caagcgattg aattccgttc cattatctgc cgtgatggaa agaatcttgt gttgttttaa
    22261 gatgagtttt agagcctgat tgaccacctc agcactttta tttggaatca atcggatgat
    22321 ctgatgtcta ctctttcgat ccgtcaagac aagcaagcag tagtttttcg ctctcgtaag
    22381 tagaaccgta tcaatctcat aatgcccatt ctccaagcga agattgatag cttcaggccg
    22441 ctgtgcgatg gattgaccag caggtttaaa gttgatgcta gcctgtttct taagcgcttt
    22501 tccttttcta gggtaaagca gatcctgttt gcttaacccc aattttccat gatgaatcca
    22561 atagtaaatg gttgaaattc ccacgttaac ccctttagcc atcaccatca tttcaggcga
    22621 aaatttttgg ttatgatagt ggagaatctt ttcctttagt tccttggtca cgcttaattt
    22681 cctgaccgag cgcttgcgat tgttttcata agactgttga gcatagtcgg cagaataaac
    22741 ctctttgaag cgcccttttc caagacattg tcggactgtc ccacgcttga tttcagtgtg
    22801 gatagtttga ggaacttttc caagcagaga ggcaatttct ctatttgatt tccctttgtt
    22861 cgccttttgt agtataatgg ttttgcatct ctgtgccttt cttgtgtttg tggttgaaca
    22921 acaagtataa cacaaaggtg ttttcttatg cctacaagag ctttcattat ttccattttc
    22981 ttttggattt cactctattc tgaaaaactt gtgtatattt actgaagcta gcaagtctta
    23041 cctgtaaatt taatgaaagc aacacaaaat ccgagagggg aatctcggat taatgtcaat
    23101 ttaaaaagat agagagtttt tagtttaaat aaattgtttt aaaatatcaa caacatcact
    23161 tcttttctta acctgataag ccttgattcc taattttggg gctacgatta tattgtcctc
    23221 aatatcgtct agaaagacac aatttctagg ttataactgg tatttatcga tagttactca
    23281 tatatatcag tccacctcca tactcacctt acagattctt ttgataataa tatctttgcc
    23341 taatgtagag atagtcttgc aaagaaaaaa cttccttgta gccatgtttc tgataaaagt
    23401 ccggtgcctg gaactggtaa gtattgacaa aggcaaaaca acaatttcga ttcttagctt
    23461 cactttctgc ctgttgcaat agttttgaac cgattccttg ccctcgcagt tcctctttta
    23521 caaacaaata ctcgatttct agccaatttc caaaagtctc tgctatcaaa cccgcaagga
    23581 gattgccctt ttcatcttcg acataaagat taagtggctc actttcagcc tcttctcttt
    23641 ttgaacggtt ataaacacga atcagattcc ctatttcttg cgatttatgt gattccttat
    23701 tttccaatct aaagtataat gaaatgaaat aaaacatgcg caaatcgatt aaggaattta
    23761 atctaatttc taacaatgtc ttagaaatca aagtgtacta ttttaacttc aatgcactat
    23821 acatctaata ctcaataaaa atcaaagagc aaactaggaa actaggcgca ggctgctcaa
    23881 aacaccgttt tgaggttgta gatgaaactg acgaagtcag ctcaaaacat ggttttgagg
    23941 ttgtagatga aactgacaaa gtcagtaacc atatatacgg caaggcgacg ctgacgtggt
    24001 ttgaagagat tttcgaagaa tagcaaaatg gaaaaaggag tgagtgaagc acatcgcctc
    24061 cccactcctt tttctgtttt taggctgttt tttcaacctt caagattttt acatcatagc
    24121 taccaacagg cgtttcaatg gttgctgtgt cacctgtttt cttgccaatc aaggcctgcc
    24181 caattgggct ttcatttgaa accttacctg caaaggcatc cgcaccagct gaacctacga
    24241 taatataaac ttcttcttcg tcctcaccaa tttcttggat ggtgactgtt ttaccaatcg
    24301 ctacttcgtc ctgggcaact gcgtcgctat tgacgatttc agcatagcgg atttttgttt
    24361 ctaagctaga gatttgtcct tcgacaaagg cttgttcatc cttagctgct tcgtactcac
    24421 tgttttctga aagatcaccg tatgaacggg caatcttaat gcgttctacc acttctggtc
    24481 gacgaaccaa tttcaattct tctaattctt tttcaagttt ctccttttcc tcaagggtca
    24541 taggatatgt tttttctgcc atttttctca actttcttct gataatattt tctaaagaaa
    24601 attatgtgaa gtatcacata attttagttt gtttagttta atttgctgtt gacatgttca
    24661 gcgacattgc ggtcgtggtc ttcttgattg ttagcatagt agaccttgcc ttctgtgaca
    24721 tctgctacaa agtagaggtt atcgctctta gtttgattga tgcttgactc aatcgcatcc
    24781 agacttggac tatcgactgg accaggcatg agacctacat ttttataaac attataaggt
    24841 gaatcaatgt cggtatcaat cgcaacatcc tcagctagac tgatattttg ccccagtttt
    24901 ccttgggcat acaagattgc aatattactt tgaagtggca tatcacgatt taaacgattg
    24961 tagaatacac ctgcaatgag cttacgatct tctgtcttgg caccttcttt ttcgaccaag
    25021 gaagcaatgg tcaacaactc attgatagtc aagtttttag atttgatagt actatagtaa
    25081 ggagataggt tcttatccat agcagctaac atctcatcaa tcaagctctc aatagttgtg
    25141 ctttccttga tagagtatgt agctgggaaa aggtatcctt ccaaacgata acgcgcaccg
    25201 ctgtctttta caggcaaact ttccagtaaa gtaggatatt tcgctactgc ttgactgata
    25261 aacgtctcat cttgaacttt agccaagaaa gcctccgctg tcaaagactc tttgaagtca
    25321 ccttgcaatt gacccacagt ttgagcaatc tgatccaagg tataaccttc tggaattgtc
    25381 aaagtcgcaa gtacaggttc ttgcggttca tctgttccac ctttttgcaa ctctttgagt
    25441 aagtcttctg tactcatact cttttgcaaa ttgtagtaac ctgctttcaa gtcggtataa
    25501 tttttatact tggcataaaa actaaaaatc agaccatgct ttaccaaacc agctttttca
    25561 agcgtcgtac cgatttcttg aacgtttgaa ccttctggaa ttccaaccgt cacatatttc
    25621 ttagaattag catcgatagg taacaaagaa tctagcacgt actggtaacc aaagtaacca
    25681 cctgctgaga gcaaggcaag gaatacaagg aatgaaatca caaaagcttt cacatgtgac
    25741 ttcttctctt tcttaggttt aacgggtttt gctccttctc tacggctacg acgtgatgta
    25801 tcgctgatga tatccactgt ttctgtagca ggcgtaggtg tttctggacc tgcttgttct
    25861 gcttttttct ctgccgtcgt ataggaaaca gctacccttg ttggggtttc attgtattct
    25921 ctttcaagtt tcttaggtct aacaggacct ggacctggtc ttgatccact ttcttccgct
    25981 ggagaagaag gtacatcttg acttggatga cttggaacac caggagtttc tctttgaatc
    26041 tcatctgctg gagaagctgg tacaccttga cttgggtgag taggcacggt aggagctttt
    26101 ctcataatct cctctaccgt tgacaaggaa tcagccatga gttcttcagc tgaaggttca
    26161 tttgcaggag tgcgaactac tgcctcatct tctttcagaa cttcatcata gccttttact
    26221 ttttctaaat ctctcagaat ctgctcttta aagcttaatt tctcttcttc tcttgacttt
    26281 tcactcaaaa gtttttcctc cttgttgata atccataata ttatatctta aaagtccaaa
    26341 aaaagcaatc tatgatactt ttcctaactt attttttcat ttcccagacc atatcatacc
    26401 atgtttcccc tgcaaaggtt gactgggact ggccttcgtt gacaaatcca tgtttttcat
    26461 agtaggcgat gagatagtca tgacaggtta gattaatgcc atctctctca tcttcaagag
    26521 caacttcttt caaggctgtc agcaatttct gacccagtcc gagtccctgt gcctccttgg
    26581 caatagacag acaggtcaca gagatataac caccaggctc atgactatag tcttttattt
    26641 cttctgtaaa agactggtct tgcagatggc ggtgcaggcc aactggtcct tcgatataac
    26701 ccatgattct tccttctttt tcagcaacca gaaaagaggt ctgaatttct ctcaaatgtg
    26761 cttcaaagac agaaggagga atggcttctt cgaccgaaaa attttcaaat tcaagttcaa
    26821 caatccgatc caaatcttct aatcttgctt gtctgatttt cattgttcct ccagataaaa
    26881 gggattaaac caaatcatac tatagccctg gctagttgca tagagcaaag tttcttcttc
    26941 atcaacaaaa ccgttcattt caaaatagga aagcagctca tcaggactct ccaaacgaat
    27001 ccctttgcaa tccagctcaa ctgccacctc tttcaaggct gcaagaagaa gtgttcccag
    27061 gccctgtctc tgatggtcag actcgatgac taaagaatgt acttttagac attgcggatt
    27121 gtctgactgg ggacttgata aaatatagcc taaaagttga ttttcatccc tagctagaag
    27181 aaaggtatcc gcacacttac ggatactttc ttctaaaata tgggaaagtt gctgcttttc
    27241 agctggaaaa gacgaggtct gaagtgcccc tatctcaggc aaatcagact tgcttgcctg
    27301 aatgatctta attggaattt ccatgggaac atcctattga acattgcttg tcaagttaga
    27361 taagagacgc tcaaatgagt attcataggt ttggatgtct cctgctccca taaagacgta
    27421 aacagcattg tcatggtcta ggagtggaga aacattttca acagtaatca cttggtgttt
    27481 tttgttgatt ttatttgcta ggtcttctac cttaacgtca ccatgatcta cttcacgagc
    27541 cgagccataa atttgcgcta gataaacagc atctgcttgg tttaaagcat gggcaaagtc
    27601 gtccaacagg gcaatggttc ttgtaaaggt atgcggttga aagactgcta caatttcctt
    27661 gcttgggtat ttctgacgag ccgcatccaa ggtcgcaata atttctgttg gatgatgggc
    27721 aaagtcatca ataatcactg tatcattgac aattttctca gtgaaacgac gtttaacacc
    27781 ggcaaatgtt ttcaagtgct cacgcaccaa gttcaaatca aatcctgctg tgtaaagaag
    27841 accaataacg gctgtcgcat tcatgatatt gtgacgacca aaggttggaa tgtggaattg
    27901 ccccaagttt tgtccacgga aatgaacggt gaaggttgaa ccagttgttg aacgaagaag
    27961 atcactagct acaaagtcat tgccttcagc ttcaaaacca taataataaa ttggtgcatc
    28021 agacgtaatc ttacgcaatt cagcatcttc accatagaca aaaagaccct tggtaatttg
    28081 tttggcatag tcgttaaagg cattgaaaac atcctcgaga cttgtgaaat aatctggatg
    28141 gtcaaagtca atgttggtga taatagagta ttctgggtgg taaggcatga agtgacgctc
    28201 atattcgtca gattcaaaga caaaatattt ggcattagcc gaaccacgac ctgtcccatc
    28261 tccaatcaag aagctggtat ctgtaatgtg agacaagaca tgagacaaca tacctgtcgt
    28321 tgaagttttt ccatgtgctc ctgctactcc catgctaaca aagtcacgca taaagctacc
    28381 tagaaactca tggtaacgtt tgtagctgat accattttgg tccgcatagg caatttcgac
    28441 gttgttatct ggacgaaagg catttccagc gataatttcc atatcaccgt ctagattctt
    28501 ttcatcaaaa ggaagaatgg taattcctgc ctgctcaaga ccgcgttggg taaagtagta
    28561 cttttcaaca tctgatccct gaaccttgtg ccccatctgg tgcaacatca aggccaaggc
    28621 actcatccct gatcccttaa ttccgataaa atgatatgtc tttgacatgt tttctcccct
    28681 attctgtcat tctggtcaga ttcaactctt gggcaacccg acgttcttgt tctgtttgtt
    28741 tacttttttt attgtagatt tggctcttct ttagaaaatc ataattgttt ttctttggag
    28801 caggtgctga cacttcttca ttcttggtag ggatagaatg aacttcttcc gccaagatat
    28861 aatgagactg ggtcaatttt tggctatatt tgacaaattc accaggattt tccttttgga
    28921 aaggagttgt cggttgattg ccctgtctaa ctagactggg ctgagaatga cgtctcgcaa
    28981 ggctgaaatc ctgagttagg tagttagcag agcgtttctt tttcaagtcc gcacgcgctt
    29041 cttcacgcgc cacctccgca tagctctttc cttctttttt aacccctaaa ggagcctttt
    29101 taggtttttc gacttgcttt tcaatcggtt ttactggttt ttcttcagta ataggagccc
    29161 attctaaata atttttatct cgatactcac ccttgatatt actgatcaga tcagactcat
    29221 catagagatt catgactggc atttcagtca acatgacctc gtcatctgac accaatggaa
    29281 atcgttcttg tttcattttc tatttccttt caacacttca ttatagcgta ttgtcttgat
    29341 ttttcaagtg ctggcttcag aaattcccaa aatttctcta atttctgcta gggtcagact
    29401 accacgtgac tctgtgccat ccaatacttg tgacaccaga tgtttctttt gttcttggag
    29461 ttcctgaatt ttttcttcaa tggttccctt ggtcaccaag cgatagacct caaccgtttc
    29521 ttcctgaccc atccgatggg cacggccaat ggcttgcgct tccaccgcag gattccacca
    29581 aaggtcaacc aagatcactg tatctgcacc tgtcaggttc agaccgaccc caccagcctt
    29641 gagggaaatc agaaaggcat ctctttctcc ttggttaaag gccttggtca tgtcttgtct
    29701 ttccttggct ggggttgaac ccgtaatttt aaaggatgtc aggcccaagt ctggcagttc
    29761 ttgttcaatt ttttccaaca ttcccttgaa ctgagagaaa atcaagacac ggtgtccgcc
    29821 gtctgccacc tgtaccagta ggtctcggag actatctagt ttgccgctgg ctccctgata
    29881 atcttccata aacagggcag gagtgtcaca tatttgacgc aagcgcatca aaccagataa
    29941 aatttccaca cgacttcgct gaaattcctg ttctgacact tgagccagat ggtctcgcat
    30001 ctgttgtaac tgggcaaggt aaatagcctt ttgctggtct tccagttcat ttttataaac
    30061 cacctcaatc aagtctggca attcagtcag aacttcttct ttcttgcgtc gcatcacgaa
    30121 aggcttgata aactgagcca ctcgctctgc tggcaatttc ataaattctt tcttgcttgg
    30181 caaaagtccg ggcatgacga tttggaaaat agaccacaac tcacccagat ggttttcaat
    30241 cggagttcct gacaaggcaa agaccgacgg caccacaaat tgtctcaagg tctgggcaat
    30301 cttggtctgg gcatttttca tgacctgagc ctcatctaag aaaaggaagt caaaggccat
    30361 cccctgataa aactcactgt cctgacggaa ggtggcatag ctagtcacat agatttgatg
    30421 gctctcggca agaatctcct cacgacttgc tttcaaacca tgaacaacag ccacatccaa
    30481 ctgtggggca aatttctgaa actcatctgc ccagttgtaa atcaaacctg acggagcgag
    30541 aatcaaaacc cgactttctt ttgtcacttg actagtcaaa aaagcaatgg tctgaagggt
    30601 tttcccaagt cccatatcat cagccaaaat cccaccaaaa ccataatgat ggagcatctg
    30661 caaccagcca attccctttt cctgataatc tcgcaagtca gcctgaacct gagttgcctg
    30721 tcgaggaaag tcctctggat gtgtcaaatc ctgggccaga ttctggaatt cttgtgaaaa
    30781 agaaacacgg tctcgccctt caaagagatg agctaaactg taggccaagg atttccgagc
    30841 ctgcaaggtc ccatctttta attcaaattg ccccagttcc tgtagatttt ggcgaatttt
    30901 cttggtttct tcatcgaaaa agtaaacttg attagacgaa tcaatataaa aatcctgatt
    30961 ggcaaccaag gcctgcatgg cttggtcgat ttcctcctgg gcaatatctt gaaaatcaaa
    31021 ctggatttcc aagagacctc ccttggaggc aatctgcacc tgaggactcg ctaggctata
    31081 aagctcttct agtttatctg ataggtcaac atgcccgagt ttttcaaaga ctggaatgat
    31141 atcatgaaaa aaatgataga cagactccgc ttttaaggcc tgacgccaag attgaaaatc
    31201 ggcttcaaag cccgcagcca aacagacttg gaaaattctt tcttctaagt ccgcgtcact
    31261 tgaaaatggt aattcttcta gctcttgtcg gctagatacc tgtctatttc cataatcaaa
    31321 ctgaatttct aaacgaatcc gattatcttc ttccctgtca aagtaaaaag agggcgcaaa
    31381 agttttgatt tgtagacgtt ctggagctga aacggtgccc atctggataa aaagagtcag
    31441 acaggaggcc aatttgtctc gatcactgct atcaaattgc aggtatttct ttccttgttg
    31501 acccacaggt aacgctttaa tttccttgag aagacgcatc tgctggtctg ttaaaaaata
    31561 aacctgacct ttatggaaaa gtactgctcc ctgataaaag acattgaccc taggactctc
    31621 actgatttcc atttcaaaat agtccgagta ttctgttact gtaaaggcaa atagattggc
    31681 atcagcatgc atatcctgaa aaagcagggt ttggtagcta tccacttgat ggtcaaattg
    31741 aaaatggggc aaggccatca gtaaattcac accctgctca aaaaaggtca gagggaaaaa
    31801 gaggtgccga ccttggtttt ggaaaaagag gtctgaaacc agcccttcct ccgttagtcc
    31861 gtgcaagaaa gtcaaaagtt cttggctggc atcatcaaag gcttcccaag aaagagactc
    31921 ctcataaatc ttgccaatca tatacgactt tctctgctcg acaatcctta aaaaaagtgg
    31981 aatatcccga atgacatagt atttttggct attgatttgg ccgattctca gagtccacaa
    32041 gatatgattg gttcctgctt ccacctgacc cacagctgat aactcatagg cgcattctga
    32101 ttttggagat aaaattcgat ccaaaaactt gccacccaag gttaccttgg tttcaacagc
    32161 ctctttttct tcatgacctt cttccagact ccacaagatt tcctgaccac gctcatcatt
    32221 tttcagaaaa tgctctagcg ctgccaaatg cacacagtaa cccctctttt gaaaaaaatc
    32281 acaggcacaa aaaaccaaat catcctctaa actatagcgc agttcttctt ctgcaacgcg
    32341 agcgtagagc cgattgttct tttccttgat gatatcaacc ttaccagttt cataaagggc
    32401 aacaccttcg atacgaattt tccccggaat caatttagcc atattttcac ctttacctta
    32461 tctttttatt ataccatatt ttcgcctatg aaaatagcct tctaggaaga cttttctcct
    32521 agaaggctgg atttttaacg tttggcaaaa gtagccacaa tccgctgaca gacttcttgc
    32581 aacagagatt tgggcatagc tatattgatg cgggcatgga gacttccttc ctctccaaaa
    32641 tccaaaccac ggttgaggat aaccttggct tcatttctca acaactcttg caatgtttca
    32701 tcagtcaggt cataagctga aaagtcaagc caaatcaagt aggtaccttg cggtttcatg
    32761 accttgattt tagtctcttt tccaaataga tccaccacat aattgatgtg gtcttcaaag
    32821 acttgcttga gttcctctag ccaatcttta ccgtatcgat aggcagcttc tgtcgccaaa
    32881 taacccaagc ctgaaatttc atgctgatta ttggccaaca ggcgtttctg gaaagctagt
    32941 ctcaacttag gattttcaat gactgcatag gaattttttg ttccagcaat attaaatgtt
    33001 ttagtggcac tactcaagac gatagcaaaa tttttgaagg caggattgat ggtattgaaa
    33061 gactggtgtt tgtgaccaaa gagggtcaaa tcttggtgaa tctcatccga aactaacaaa
    33121 acaccgtgtt tttggcagag ttggccaatc ttctccaaca cttctttttc ccaaacacgt
    33181 ccaccaggat tgtgagggtt gcaaagaata tagagtttaa cctcctcttc caccaaatcc
    33241 ttttcaagtt ggtcaaagtc aatctcaaac agaccatcct tttccactaa ggaattagta
    33301 atcaatctac gattattcaa cttgacactg cgagcaaagg gtgggtagac aggcgtgtta
    33361 attaaaaccg cctcgccttc ttttgtaaag gtttgaatag ctgttgagat ggctggtacc
    33421 acaccctcga taaagacaag agcctctttg tcaaagttgt aaccgtattg tgtagcttcc
    33481 cacttttgaa cttccttaat taagtcttca ctggcatagg tataaccata aaccagttgg
    33541 tctgcgtaag tttgcacggc ttggcggatt tcaggcaaga ccacaaagtc catatccgct
    33601 atccaagctg gtagaacttc actatccgtt tctgtttctt tccatttata ggtatggtgc
    33661 cctaaacggt tgggcaggct tgtaaaatca tattttccca tctttgtctt atccttctaa
    33721 ggcttggcgc aaatctgcaa tcaaatctct agcatcctca atcccaatag acaaacgcaa
    33781 gaggtcatct gtcaaaccat aagaatggcg tacttctgct ggaatatcag catgagtttg
    33841 agtcgttgga taagtaataa gactttccac tccgcccaaa ctttccgcaa aagagaagac
    33901 cttgagactg ttcaaaatat gaggaatgcg tgtttcatcg gctactttaa aggaaatcat
    33961 gcctccacga ccagtgtaga gaacttcctt aactgctgga gaatccttca aaaaggcaac
    34021 cacttcttgg gcgttagctg ttgagcgctc catacgaaga gacaaggtct tgagaccacg
    34081 aagcaactgg tagctgtcaa atggagacaa gactgcccct gttgtattga gattgtaaaa
    34141 aagcttctcg tatagttcta aactattggt cacaaccact ccagccaaga catcattgtg
    34201 gcctgctaga tacttggttg ctgaatggag aacgatatct gctccatctt caatcggacg
    34261 ttggtagata gggctataga aggtattgtc caccaccact ttggcaccct tagcatgagc
    34321 caattttgct agtttttcga tatcaaattc caacatcaag ggattggttg gggtttcgat
    34381 atagagaaca tccacatcct tttctaactc ggcaatcaac tcttcttctg tattggcata
    34441 ggtaaaatgg aaacgacctt cctgctccac ttggttaaac cagcgaaaag aaccgccgta
    34501 aagatcacgc actgccaaga ccttacttcc tactggaaag ccgctaaagg ccagtacaat
    34561 agctgacatc cctgagctag tcgctaaggc atagtctgct gactcaatag tcgccaagac
    34621 ttcctcagcc ttactacgag ttggattttt agtgcgcgta tagtcaaacc cagtagatcg
    34681 accaaactct ggatgctgat aggtcgttga aaaatgaagc ggtgtcacca atgcacctgt
    34741 cgcttcatct gacttaatac ccgcctgggc caaaattgtg ttaatgtgta attccttgct
    34801 catacaatac ctccaaatct atagtaacta ttgtaccact tattttcatc aactcatttt
    34861 cttcttttca agagctagtt atagtttcaa actatataaa aagggagttt ttcctgctcc
    34921 ctttaataga ctataaaatg gtgaatctca aaagacacct tcactctatc atttgctcct
    34981 gcacaaaacg agcataacgc tcatgatttt ccagtagttc cttatgagtt cctgagccag
    35041 ttattttccc ctcctctaag aagaaaatac aatccacatc ttttaccgtt gacaaactat
    35101 gcgctataat cacaaccgtc ttctccttta atacagaata gaggctactg ataatcgcat
    35161 actcagaatc cgcatcaaga ttagcagtgg cttcatcaaa tataagaatt tcagcatctt
    35221 ttaagtaggt tctagctatt tgaagtcttt ggctttgccc cctgacaaga atcgtccgcg
    35281 ttcaccaact tcagtatcta gtccctcttt catggagcga atctcatcac ctagtgatac
    35341 taagtctagc actttcatca attcatcatc agttactaag cgattcaaac cgagacaaag
    35401 attgtcacga atactgccag ataagactgc attattttgt gaaacccaag cgattttact
    35461 tctccattct tttaagttaa aatcatatat acttgattgc tccattagaa tatctcctga
    35521 aagcggttta taaaaccgct ctaacaaacg cacaatcgtt gattttcctg atccagatgg
    35581 tccaacaaaa gcaatttttt gccccttgaa aattgaacaa gtaatatcct ttaagacagg
    35641 tcgattttca tcataaccaa aatagacatg gttaaaattc aacccttgtc ctgataccga
    35701 ttttcctcac tcaaattttt ctttaggaac tgcaagcaag ttctccagtg caactgaaga
    35761 tcccttgctc ctagaataaa cagttacaaa attagctata ttactaatag gattaagtaa
    35821 ttgaaagagg taaatcaaaa acgaaaccaa ggttcccaca gatatatatc ctgcgctgac
    35881 ccgataaccc ccataggtta gcatcacagc tatagtcgca aagataaata agagagcaaa
    35941 cggggtctca aaagaagtaa ccctatctga tttcagtgaa ttgttttgta ccctttcaat
    36001 acaattatcc aaaacatcct gtacactttt ctctgcttgg ttagtcttaa ttaattcatg
    36061 ttcttgaatc ttttcagtca attgccctgt taaaaatccg atttcctcct gtaaacgacg
    36121 actatacttt tcactgatat tggaaagggg caagataata aacatcatac aaggaagagt
    36181 gatgaataaa agtagagaaa gattccaatc aagactaaat aagactacaa tggaaccaag
    36241 taccataact aaactcagaa taatatttgg gaaagtcgta attaaaaact cacgaatgac
    36301 actcgtgtca ttgacaatag cagaagtcaa ctccccactt tggttcttat caaagaagga
    36361 tttctctgca taaatcaacc cctctatcac ttttttcctg atttttgcta tcttttttca
    36421 cccgattgac taaaaagata gtaaccaata gaagaaaaca aggcttgacc aataaaaatc
    36481 aaaaacgatt gaaatacttt ggaacctata ttttcaatag aactcccatc tattaaaccc
    36541 tttaagataa ggggaagcaa caaagcaagt agactagaca gaacaaggaa gaaactcccc
    36601 ataatcacct tagtatctac tcttaataat tttaatttca taaatactcc ttataatatt
    36661 tcaacggata aagtcaggaa taactcaatt tgaggataaa atctaataaa tcttcctata
    36721 acaaaacgca taacatctag gattttatat acctgatatt atgcgttttt aagcacaaag
    36781 acttcttaca caaacttatc tacaattaga ttttatttga catgttttgc caattcttct
    36841 tgggcttttt tattggattc ttctttttct ttcaaccatt tttctctggc ttttgcatat
    36901 tcgtctgttg tgacaatctt atcttgtact ttgaggtatt tatatgattc aacccctttt
    36961 gtaccggtta aaccataggc accagcaaat ggtacggttc ttctcaatga tggggttccc
    37021 ccacgcgaaa cacttggaag aactaaagaa ctatcaatca accaagcttg aatatcagca
    37081 tatttctcat aacgtttggc tggatcttgc tctttattag cttcttccaa catttgagta
    37141 taggtatcaa gcccaaccgc cttagctttt tcattaactt cacctggttc taaaccgaag
    37201 ttttgcagca ttccgccact cttcacactc aagatgtcca gataagttga tggatcttgg
    37261 taatcaggtc cccaaccgcc atgatataaa tcatagtctt tctgagcagc tgtttgagca
    37321 aagtagcctg aactgtcaaa ctcatctgat gttaattgct gaatgtcaat cactacatta
    37381 tcagaaccta aaacagattc aattgattgt ttgatagaac taactccttg tatgcctact
    37441 ttatctgtta cttccacagt cttatccaag tggattggga attgaacacc ctttgcttcg
    37501 agttctttct tagcttccgc aaacttagcc ttggctttct caggattgta gtaagggtct
    37561 tgaccatccg caaagttgat accttgccat tccttaccat agttgaccat cttagaggct
    37621 acaacttcac caaagtcttt tcccttgata ctgacaaagt ttggaggaac cactaggtta
    37681 cgcaaaatct ttgttgcacc ttctttccct tcagactgag ccccataaga tgttctgtca
    37741 aaagcaaaat tgatagcctg acggaagttt ttattgagaa ctgcttcctg agtcgatttc
    37801 ttttcaatgt cacttgtttt agaagtataa ttgtaagact tcctatctag gttaaaatta
    37861 aagaaatatg aagttgaatt ttgcatacta tagatgatat tgtttttgta tttttcttta
    37921 atcccttcat agctggagct gttaggaaaa agacgagccg tagtataagc accagctgta
    37981 aaattacgtt ccagtgattc ttggtcgcta ccatcatagt aggtcaattt cacatcgtct
    38041 acaaagacat tcttagcatc ccagtaatta gggtttttct tatattcaat agcagatttt
    38101 gagacaagtg ctttcatcaa gaaaggtcca ttgtacaaaa tactagatgg atccgccttc
    38161 ccaaaatcat ccccttttga tttcaggaaa tctgcattaa caggaaaaag tatcgttgca
    38221 agtgtttttg aattccagta aagttctggt ttaaccaaag tatattgaac cgtttggtca
    38281 tcaagtgcct tgacaccgac agttgaaaag tcgcttgttt taccagtgat atagtcatcc
    38341 aaaccagcaa cagagtcctg cactagatac aaggcttctg attttttatc agctgcatat
    38401 tgcaaacctg tcacaaaatc ctgggcagtt acaggcgcat attcttctcc ctcagaagta
    38461 aaccacttgg catccttacg aagtttgtag gtataggtca aaccgtcctg agaaacagtc
    38521 caatcctctg ctaatgatgg aataatattc ccatattggt cattttctaa taacccgtct
    38581 accaaatttg caacaatatc ggatgttgct gcgcggtttt ctgctagata gttcaagcta
    38641 gatggatcac ttgaataaac atagttgtat gtttttgacg ccgtgctaga atttccacac
    38701 gcgctcaata aaactcctgt acccaggaca agacctgcca aggttagata tttgctctta
    38761 gaccttttca tttccggaac ctcctgcttt aaatatttgt tttattatac aacgtttagt
    38821 ttgtttaatc aatgattttt tccaaaaaat cgaaaaaagc ctcattttct atttttgaaa
    38881 tataatttta gctattttta cgctaaaaaa ggaataagct tcaagttctc ctaaaagatt
    38941 gttcaactta ttccttttat ttataaatgc taccttacga aagcttaaat tttgctcgca
    39001 ggcgatctgc ttgggctttt cctattacct tatctaataa ataggtacgc agactcataa
    39061 ccatataaag tccacccccc atggcaccga caagagctac ataaaagaag ctccacaaac
    39121 gtccacttgg ttggaagaaa aatcctaaca gccactggat ggttcctatt aacagaaaca
    39181 tgactagggt cagcaaactg attaaaatgg ttcgcttcaa aatcaccttg cgcttgacac
    39241 cagttacttt acaaatatcc cgatacatca agacgttagg aatgatgaga gcaatggttg
    39301 ttgaaatcaa aggaccataa ctgtggaaga gggcgatggt aggtagttgc aagactagct
    39361 tggcaataga accatagata aaatagagaa cggccttgcg gttgcggaac atggcctgaa
    39421 gcattggaga caagaccatg tacaagccta aaataataga ctgcaaaact gcaaagacaa
    39481 ataagcccag agccaaacta tctggcttac catagaagac cgtataaaga ggttctccta
    39541 ccataaccac tccaaccgtt gctggtagca agaacataaa gagtagggtg agactgtcct
    39601 gaacgagacg agaagctgct ttcaagtccc ccttgacata gttttccgtc aaaagtggca
    39661 aaccaacact cccaatcgaa acccctacag aaatcaaaat catcgtgatt ttattaggat
    39721 tggctgagaa ataagaaaac atgacaacca agtcctcatt gctgtagttg gtaaaccagc
    39781 tcatactatt gataaaggtc agctgatcca aaatctggaa gagctggatg gcagaccctg
    39841 tcaggataaa aggaatggct tccttaatgg tatcaaccaa gagacgctta ctgttaatct
    39901 tatctcctgt ttcaaagact cttttgagtg aaccttcttg ggcaaggaaa taaatcaaga
    39961 ctgcaaaact ggctaccata ccgacaaagg cagcaaaggt tgattgggta acggctgcta
    40021 gataatctcc tgaaccgagc ttcataatga taaaggttgc taggagcatc cagataacac
    40081 gaatgacctg ctcagcaatt tggctcatgg catagggttt gaggttattc atcccttgga
    40141 aaaatcctcg gataacactc atagacggga aaatcaagac tccccaagcc aagctttgca
    40201 tgattgggat caagtctttg cccacgccag acaagtctgc tagccaagga gcaaagacat
    40261 acaagactaa agcaaaaacc aggcctagtc ctgtcataaa gcctaagaag ctccgaatca
    40321 gggcaaagct atgctcttct tctcgcatgg tattatactt ggcaacttgc ttggccaccg
    40381 caactggaat ccccgctgtt gaaaccaaca agaaccaagc atagatattg taacccatgg
    40441 taaagagacc atttgcctta gctgcataag cccccatcca gatgtaccaa gggataatgt
    40501 aaacagcccc gagtaggcga ctgataaagt tactagccgt tagccaagca gtcccccgta
    40561 acatctgggc ctgctggtga ttgttttcgt gcgacataga ttcctcattc aattttgata
    40621 actaggaaaa actccttatc ttccattata aacttttcct tgttacttgt aaatttgcga
    40681 ctttcggttt acaatagaaa gtatgataaa aattgaaact gtattagata ttttaaagaa
    40741 agatggcctt tttcgcgaaa ttattgacca aggtcattac cactacaact acagcaaagt
    40801 tgtttttgat agcatcagct acgacagccg aaaagtaaca gaagacactc ttttttttgc
    40861 aaaaggcgct gcctttaaaa aagaatacct tctttctgct ataacacaag gcttagcttg
    40921 gtatatagct gaaaaggact acgaagtcgg tatccctgtc atcattgtga acgatataaa
    40981 gaaagccatg agtttgattg ccatggagtt ctatggtaat ccacaggaaa aactcaaact
    41041 ccttgccttt actggtacta agggtaagac aacagcagcc tatttcgcct ataacatctt
    41101 atctcaaggg catcgacctg ctatgttgtc gaccatgaac acaactcttg atggagagac
    41161 tttctttaag tcagcgttga caacccctga gagtattgac ctctttgaca tgatgaatca
    41221 ggctgtgcaa aatgaccgta cccacctcat catggaagtc tccagtcaag cctatctggt
    41281 caaacgtgtc tatggtctaa cctttgatgt gggagttttc ctaaatatca gcctagacca
    41341 tatcggcccg attgaacacc ctagctttga agactatttc taccacaagc gtctcttgat
    41401 ggaaaatagc cgagcagtca tcattaacag tgacatggac cacttctcag tcttgaaaga
    41461 acaggttgaa gatcaagacc atgatttcta tggtagccaa tttgataacc aaatcgagaa
    41521 ttccaaagcc tttagatttt cagctacggg taaactcgct ggagattatg atatccaact
    41581 cattggcaac ttcaaccaag aaaatgcagt tgctgctgga cttgcttgtc tccgtctcgg
    41641 agcaagtctt gaggacatca aaaaaggcat cgctgcaacc cgcgttcctg gtcgtatgga
    41701 agtcctcact cagaaaaatg gagccaaggt cttcatcgac tatgcccaca atggggatag
    41761 tctgaaaaaa ctcatcaatg tggttgaaac tcatcaaacc ggaaagattg ctctggttct
    41821 gggatcaaca ggaaacaagg gagaaagtcg tcgtaaggac tttggcctcc tcctcaatca
    41881 acaccctgag attcaagtct ttctgactgc tgatgaccct aactatgaag acccaatggg
    41941 cattgcagat gaaattagta gctacatcaa tcatcctgtt gagaagattg cggatcgcca
    42001 agaagccatc aaggcggcaa tggctatcac aaatcacgaa ttagatgcag ttattattgc
    42061 gggtaaggga gccgattgtt accaaatcat ccagggcaag aaagaatcct acccaggaga
    42121 tacagccgtc gcagaaaatt atttataaga atagaaaaaa tcaagggaaa atgaaaccct
    42181 tgattttttc ctattattta gtaaaaacgt ttttcaaacc ttctacagca ccttttgcgt
    42241 cttctacaac gtcttttgcc ttagcaactg ttttttcaac agctccttca agttctgtct
    42301 tgctgtctcc agtaacttta ccaaaacctt ctttgacagc gcctgttgct tgttccaatt
    42361 tgttttcaag tgacatatga ttgtctcctt tagtttattc cgatatgtgt taccggttac
    42421 atatagttta taccgaatac taaggaaagt caaacaatgt actcagaaac aagaaatcac
    42481 gctaagtaga aagttaatct ctccttatca aaatcgatag ccaactcata ctttccatct
    42541 tcattttgca caatatagcc taagacaacc aaactgtcca caaagatatc acggcatttc
    42601 tgcataagct ggtctttttt gagaaatttc aacaaaaaag ccgtcatata cttgagggca
    42661 tactcaggat taacatctcc taaaatgtca tagagctcct gctgtttttc tgtcaaagga
    42721 tactgctgtt tgaccttgta aaaataattg gacagggtca ttttaatgcg cgcaaagtcc
    42781 gtcttttcaa ctaaaatagc tgcattgatt tgattgcgca attccgtctc aaaactctgc
    42841 tccaacaagg cttgatagac cggactagct tctctgacaa aaatctcttg atccagttca
    42901 agactatcaa gtgattcaag cgtaggaaaa ttaaggtaat agcgcttatt ttcacataga
    42961 atcacatcct catactggtc cagatagcgg atcaattctc caaaaatggc tgtctcgtca
    43021 aacgagatgg attaaaaatc tgaatcacga agattccttt ctttacattg taacagaggc
    43081 gatgctgcca actgactagg attggtccca gcttggttca gaggaacagg cagacctagt
    43141 tctatgtaat actccctcca aaaatcacta atctcctgtt ccccatctcc aaatttcata
    43201 ggaatagttt caaaaatagg taggatttct gctatatact gggagcagta gaaaccagct
    43261 gcatctggat agaaagaagc attgtagggt gctccaagat gtttgcaagc tctttccttc
    43321 accgactgga tatccatttc tgggtaaaca tagaggtcgt ataaatgatt ggactcaaag
    43381 aagtctgccg gttcttgaca gacaacacca gcctgtccac tagcatgata aatcatccca
    43441 tccaaataaa tggcaacatg gctatagtta cctgtggaag tctggatggc ctgtcccatg
    43501 tctgacccat ctctcacaaa aatcaaatcg ccattttcta acatacttca ctcctagaaa
    43561 aaaggagccg aaactccttt cgatataagg caaactagac tttccgattt tgagctgaca
    43621 cccaaaatct tacgcattaa agctttcagt caattgaggt accacttgtt tcttacgtga
    43681 aacggcacca gcaaggaagg catgattgtt ttcaagtttg aagttgaaag ccgcttcgac
    43741 cttgtccata ttggcaccaa gagccaagat ttctgagttt gagttgacga tatctgtaat
    43801 catcaagaca aagtcagagt agccgtttga ttcgttggca gcttgcattg cagcttcaat
    43861 ttctgcttgg cgttccaaaa cttcagcgat gtcaactgtg ttcacttggg caacacggac
    43921 attatttccg ttgagttcaa aagtcttagc atcgatgtca atcaattctt cagcagattt
    43981 gctagccaag ttggtaccag ctttcaacat tgccaaacca tattcttcca agttcacacc
    44041 agccaattca gccaattcag gagcaatgat tttatctgtt gggtgtgttg ttggtgattt
    44101 caaaagaagg gtatctgaaa tcaaacctga aagcatcaaa cctgcaatct ctttaggcac
    44161 agctacacca tgttctttga acatacggta aacgattgaa gacgctgatc caactggctc
    44221 caaacgcatg taaagtgggc ttgcagtttc aaagttagcc acacggtggt ggtctacaac
    44281 accgtaaact tctacttcag cgatatctga tacagattgt tggaattcat tgtggtcagt
    44341 caagataact tgctctgccc cctctgcttt ggcagaagtg ataacacgtg gtgcttccac
    44401 accaaaatag ttcaagacaa aggctgtttc ttcatttgga gttccaaggg caacagcttc
    44461 cgtatccaaa ccgtaagctt cttttgcaag gtaggcaaaa gctacagatg acccgatggc
    44521 atctgagtct ggattttggt gaccaaatac tagaatcttg gacatgataa tacctcattt
    44581 tgtttatttt ctttattgta gcattttttt cgctttttga caaaggtaag aggagtcaaa
    44641 ggactcccca cgattcttca aaataactga gtaaatttct atcttgattt tcagataaaa
    44701 attcttcctt ctgtggcctc ttcttacgct tgagaagagc ttcagccgac atggcttctt
    44761 ccttactggc aaaaccttga gcatagataa gtttgactgg caagcgtgct cgtgtatatt
    44821 tggctcccct cccactattg tggatagcga ggcgtcttct cacatcagtc gtatagccta
    44881 tatagtagga tccatcacga cactccagaa cgtacatata agccttatga tccataataa
    44941 atctcttcga tttcgggcgt ataagagcca tcatcattgt ggacaatcaa aggaggtaag
    45001 accttaaagc cacttgttga gccatccttg attgcctcaa tcaaaagcat attggcttcc
    45061 ttttctcttt ttggataaac aaactgcagg cgcttagggg ctagattatg tcgttttaac
    45121 gtatccaaaa tatccagaag tcgatcagga cgatgaacca tggccaaacg cccattagac
    45181 ttgagaatac tctgagcact acgacagatt tcttccaaat tagtcgtgat ttcgtgtcga
    45241 gccaagagat aatgttcact ctcgttcaga ttagaataag gatccacctt gaaatagggt
    45301 ggattacaca aaatcatatc caccttactc ccctgaatgt gagctggcat atttttcaaa
    45361 tcatcgcaga tgacctgcat ttgctcctct aatccattca aacggacaga gcgttcagcc
    45421 atatccgcca aacgctcctg aatctcaaca gacaatatct gtgcttgagt acgagtgcta
    45481 gcaaaaagcc ccactgctcc attcccagca cagaaatcca caatcaaccc cttcttagga
    45541 aaacgtggaa atcgtgataa gagaacacta tccaccgaat agctaaaaac ctctctattt
    45601 tgaatgattt tgatatctgt cgaaaagagc tggttaatgc gctctcctga ttttaataat
    45661 tgttcttctt ccatggtcct attatagcaa atttatatta acattacaaa aaatataaaa
    45721 ctctaaacta cttcttcttt tttaaatggt gcagggcttc tccagtccag attggtaaca
    45781 ttcgtcgaaa gggagcaaaa ccgtagttaa agcggtcgct tgaaaagcgt ctccgtctag
    45841 gaaactggta cttttcttcc tccaaagtgc ggatagaaag actggctttc cccgtaaatt
    45901 catctaaatc cactacctga acttgaacct cttcatcgac tttcaaggtt tcatgaatat
    45961 tttcaataaa tcctgtccga atttctgaaa tgtgaatcag ccccgtatca cccgtctcta
    46021 actcaacaaa ggcaccgtag ggctgaatcc ctgtaatacg cccctttagc ttatcaccga
    46081 ttttcatctt agtcctcgat ttcaatagtt tcaattacaa catcttcaac tggcttgtcc
    46141 atagctcctg tctcaacagc agcaatggca tccaagacag cgtaagatgc ttcatcagct
    46201 aactgaccaa aaaccgtgtg acggcggtct aggtgaggtg tcccaccttg attggcatag
    46261 atttctgcaa tcggttctgg ccaaccacca cgagtaattt ctttcttaga ataaggtagg
    46321 tgttggtttt gcacgataaa gaactggctg ccgttggtat ttggaccagc atttgccatg
    46381 gaaagagcac cacggatatt gtaaagctct tctgagaatt catcctcaaa agattcgccg
    46441 tagattgact cgccacccat accagttcca gttgggtctc caccttggat cataaagtcc
    46501 ttgataatac ggtggaaaat gacaccatca tagtagccat cttttgaaag agatacaaag
    46561 ttagccactg ttttaggagc atgttcaggg aaaagcttga tacgtaagtc tccgtgattg
    46621 gtcttaatag tcgcaagagg accttctact gtttcaatgt ctacttgtgg aaaatgcaat
    46681 tctttttcta ccataccaaa tacttctaag gcagcaaaaa tgccatcttc ttctaatgtt
    46741 tttgtaatat aatctgcttt ttctttgatt ttatcatgag aaattcccat ggcaacgctg
    46801 attccagcat aatcaaagag ttccaagtcg ttgagaccat ctccaaaaac catgaccttc
    46861 tctggtttca agccaaggtg ttccacaacc ttttccaccc ccgtcgcttt ggagcctgaa
    46921 atcggcacaa tatcagacga atgttgatgc caacgaacca tgcgaagttt gtctgagaga
    46981 ctgtcaggca agtgcaagtc atctccctta tcttcaaaag tccacatctg atagatatct
    47041 tctttttcat ggaaatcggg atctacatct aagtcgggat aaattggatt gatagcttca
    47101 ctcatcatat cggtgcgagt cgacaacttg gcatcatgac tcccaaccaa gccatactca
    47161 attccttctt gcttagccca agagatatac tcctcaacat ctgacttttc aatctgatgc
    47221 tgataaatga cctgaccttt tttatcttcg atataagccc cattcaaagt tacaaaaaag
    47281 tcaggcttga gatcacgaat ctctggaaca acaccaaaaa tgccacgtcc agaggcgatt
    47341 cctgttaaaa ttcctttttc acgcaactgt ttaaaaacag tgggaattgt agttggaata
    47401 aaccctgtct ttgaattccg caatgtatca tcaatatcaa aaaagacaat cttgatcttc
    47461 tttgccttgt atcttaattt cgcgtccatc tcactacctc tttcaatcta actctttcca
    47521 ttatatcata aagtaggcaa atcccctatt ttcaaaaagt ttatcatttt tattttaatt
    47581 tcttggatga gaaaagagac atatttatga aaaagctcca tcgtgctttt aatgtgttct
    47641 cttgttttca aactcgtaaa aagggagcca ctgagcctaa ctcgctctct catttcaaag
    47701 cttgtgaaaa aagacccgtt ggggtcttaa ttcgctttct tgttttcaag ctcatgaaaa
    47761 agagacccaa ctgggtcttt tctttaatct tcgtttacga aaggcatcaa agccattacg
    47821 cgagcgcgtt tgatagctgt tgttacttta cgttggtttt tagctgaagt tcctgttaca
    47881 cgacgaggaa ggattttccc acgttctgaa acgaaacggc taagaagctc agtatctttg
    47941 taatcaacat attcaatttt gtttgctgcg atgtaatcaa cttttttacg gcgtttgaat
    48001 ccgccacgac gttgttgagc catgtttttt ctcctttata agtttagttg tccattagaa
    48061 tggtaaatca tcatctgaaa tatccaatgg gtttgttgct ccaaatggat tttcattacg
    48121 tgaaaagtct ggtactgaat ttgtaggtgc tgaatagttt gcagttggtg cagagtaagc
    48181 tccacctgtg tgaccctcac gcacactacg gctttccaac atttggaaat tctcagccac
    48241 gacctctgtc acgtagacac gttgtccttg ctggttatcg taactacgag tctggatacg
    48301 acctgtcacc ccgataagtg agcctttttt agcccagtta gcaagatttt cagcctgttg
    48361 gcgccacata acgacattga taaaatcagc ctcacgttca ccattttgac tcttaaatgt
    48421 acggtttact gcaagagtaa aagtcgcaac tgctacattt gatggggtat aacgcaactc
    48481 agcgtcacgt gtcatacgcc ctacaagtac aacattgtta atcatagttt accttcttac
    48541 gcgtcaattt tgacgatcat gtgacgaaga atgtcagcgt tgatttttga aagacggtca
    48601 aactctttaa gagctgcatc gtcatttgct tcaacgttaa cgatgtggta aagtccttca
    48661 cggaaatctt ggatttcgta tgcaagacga cgtttttccc aagtttttga ttcaacaaca
    48721 gttgcaccgt tgtcagtcaa aatagagtca aaacgtgcta ccaaagcgtt tttagcttct
    48781 tcttcaatgt ttggacgaat gatataaaga atttcgtatt tagccattga tatgttcctc
    48841 cttttggtct aatgacccca agactttgca aggggtaagt gaggttcgct cacaataaac
    48901 tattatacta gaaaaaattt ttttacgcaa gtaaaaacac tagaattcga aaaaacgcca
    48961 catgggcgtt ttcctgttct tatggtttga tacggtgcaa catacgtggg aatggaatag
    49021 cttcacggat atgttttgtt cctgctgcga aggttaccat acgttcgata ccgataccaa
    49081 atcctccgtg tggaactgta ccgtatttac gaaggtcaag gtagaattca tattctgtac
    49141 gatccatgcc aagttcatcc atcttagcga caagggcatc gtaatcttcc tcacgcatag
    49201 acccaccgat aatttctcca tagccttctg gagcaagcaa gtctgcacaa agcacgcgct
    49261 ctggatttcc aggaactggt ttcatgtaga aggccttgat ggctgctgga tagttcatga
    49321 caaatgttgg cacaccaaag tggtttgaaa tccaagtttc gtgtggtgac ccaaagtcat
    49381 caccatgctc aagatgctcg tagtcagcat cttcatcatt ttcatgctct tgcaagaggt
    49441 caatggcttg atcgtaagtg atacgtttga atggctctgc aatgtagcgt ttcaagagtt
    49501 ctgtatcacg ttccaaggtt tccaaggctt gaggcgcgcg gtcaagaaca ccttgtagaa
    49561 gagctttcac ataagcttct tgcaagtcaa gcgactcatc atgtgtcaag tatgagtact
    49621 cagcatccat catccagaac tcagtcaagt gacggcgtgt ttttgatttt tcagcacgga
    49681 aaactggacc aaagtcaaag acacgaccaa gagccatagc ccctgcttct aggtaaagct
    49741 gacctgattg gctcaagtag gctggcgttc cgaagtagtc agtttcaaag agttctgtag
    49801 aatcttctgc cgcatttcct gaaagaattg ggctgtcaaa cttcataaaa ccgttcttgt
    49861 caaagaactc ataagttgca tagataatag cgttacggat ttgcaacaca gctacttgct
    49921 tacgagagcg tagccacaag tgacggttat ccatcaaaaa gtctgttccg tgttcttttg
    49981 gtgtgattgg gtagtcttga gattcaccga tcacttcgat gtctgtgatg tccaactcat
    50041 agccaaattt agaacgttcg tcctctttga caatacctgt cacataaaca gacgtttctt
    50101 ggctcaagcg tttgataaca tcaaacttct caagtcccac ttcttcacca aatttttcga
    50161 caaagtttgg tttaaaagcc acaccttgaa agaaggctgt tccatcacgc aattgtaaga
    50221 aagcgatttt tccttttcct gatttgttgg caacccaagc gccaatcgtc acttcctgac
    50281 caacatagtc ttttacgtca ataatcgtta cacgttttgt cattattttt ccttttcttt
    50341 tttattcttt atggcaaacc acctctatat tgttcccatc caggtcaatc ataaaagcag
    50401 catagtaaat cggatgctca cttcgataac caggagcccc attgtctcgc ccacctgcct
    50461 ctaagccagc ctcataacaa gcctgaactt cttccttatt ttctgctaaa aaaagcaaaa
    50521 tgaacaggat cttgtgttcc ctgagtcagc caaaaatcac caccaggatg agggctgttc
    50581 ggggatagaa aactaattag agaactagtc ttaaaagcca atttatagtc caaaggagcg
    50641 agaaaactcc tataaaatcc ttctgaaatt tgtaaatcct ttaccttaat ctcaaaatga
    50701 tcaatcattc tcactaccca taaatgcttt caagcgttcg actgcttctt taagcgtgtc
    50761 taggtctgtc gcatagctga ggcggacatt ttctggtgct ccaaatccag ctcctgttac
    50821 caaggccact tcggcttctt ctaagataac agttgtaaag tctgtcacat ccgtgtagcc
    50881 tttcatctcc atggcctttt tgacatttgg gaagagatag aaggcccctt gcggtttgac
    50941 cacttcaaat cctggcactt ctgcaaggag gggatagatg gtattaagac gttcctcaaa
    51001 ggcctgacgc atgctttcta cagtatcttg ctcacctgat agagcctcaa ctgctgcata
    51061 ttgggctact gctgacggat tcgaagttgt ttgacctgca atcttggaca tggcagcgat
    51121 aatgtctgct tctccaacgg cataaccaat ccgccaacca gtcatggcat aggttttaga
    51181 cacaccattg atgaccactg tttgcttgcg aatcgcttcc gataggctag aaatcggtgt
    51241 gaactcatga ccattataaa ccaagcggcc atagatatca tctgctagga tgagaatatc
    51301 attttctaca gcccagtttc caattgccaa gagttcctca cgggtgtaaa tcatacctgt
    51361 gggattagat ggcgaattca gcaccaaaac cttggtcttg tcagtgcgag ctgcttctaa
    51421 ctgatctacg gtcaccttaa agtgattgtc ttccttagta gaaacaaaga cgggaacgcc
    51481 ttctgccatc ttgacctgat ctccatagct aacccagtat ggggttggga tgatgacttc
    51541 atcacctgga ttgaccacag ccataaagaa ggtatagaga gaatatttgg ctcccgcagc
    51601 gactgtcact tgatttgacg ctacagaata gccgtaaaag cgctcaaagt agctattgac
    51661 cgccgcctta agctctggca gacctgaggt tactgtataa aaagaagcac gcccatctcg
    51721 aatcgatgca atggcggcat cttggatatt tttgggagta gtgaaatctg gctcacccaa
    51781 ggttagagac aaaatatctc taccctcagc cttcagtgct ttggcacggg ctccagcagc
    51841 caaagtcaca ctttcttcca tttctaaaac acggttggat agtttcatag gccctccttg
    51901 ttgaccaatg ctcctgtttc aaaatctact agataaaaat cagatcctga cttaacttcc
    51961 cagattggct tatcttgata acggccaaag gttatcttgt caatctcgcc agctcccttt
    52021 tccttagaaa ccgtttctgc tttttcttgt gaaacaccct gatttagctg ataaacgtaa
    52081 atcttatggt catctttacc aatcaggaca gcaagcgctt cttgctgttt gttacgacca
    52141 agaacgctgt aataagattc caagccattg tataaatcaa cctgatcagc ctgctctaat
    52201 cctgcatact gctgagctaa tttttctcct tcacttttag ctgtttgata gggtttcatg
    52261 ctaagagaaa ccatatacag aaaggaacca ctgataacca caaacaaaat cgtcatccct
    52321 agaccatact gccacagtag attatttttt gctttgtttt gtcttttttt cactcgtcta
    52381 ttttaccatc tattaagctt tattacaagt gaatataaga atactcttcg aaaatctctt
    52441 caaaccacgt cagctttatc tgcaacctca aagctgtgct ttgagcaacc aattctattt
    52501 ctcccttcaa acaaaaccga ttttgaaagt gaaacagttc ttactttttc agtcacaaat
    52561 gattagagtt tccgaaattt tacaattttc aaataaactc tgagcaaatt tcttgcaagt
    52621 tcttttgttt tgttgtaata tattttataa caacgagaga gttctcgaaa ttttaagaaa
    52681 aaggagacac atcatgtcta aaaaagtatt atttatcgtc ggatcactac gtcaaggttc
    52741 tttcaaccac caaatggcgc tcgaagctga gaaagctctt gctggtaaag cggaagttag
    52801 ctaccttgat tattcagccc ttcctctctt cagccaagat ttggaagttc caacatatcc
    52861 agctgtagct gctgctcgtg aagcagttct cgttgcggat gctatctgga ttttctctcc
    52921 agtctacaac ttctctatcc ctggtacagt gaaaaacttg cttgactggc tatctcgtgc
    52981 ccttgacttg tctgatacac gtggcgtttc tgcccttcaa gacaagtttg tcacagtatc
    53041 atctgtagcc aatgcagggc acgatcaact tttcgctatc tacaaagacc tcttgccatt
    53101 tatccgtaca caaggcgttg gtgatttcac tgctgcacgt gttaatgact ctgcctgggc
    53161 agacggaaaa ttggttcttg aagaaacagt cctaaactca cttgaaaaac aagctcaaga
    53221 cttggtcgaa gctatcaagt aactaacact caataaaaat caaaaagcaa actaggaagc
    53281 tagccgcaag ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagtg
    53341 acatatatac ggtaaggcga cgctgacgtg gcttgaagag attttcgaag agtataacat
    53401 aataaaagcg aacaagacta cttttctgac actcagaaga ctagcttgtt cgcttttttt
    53461 ctcatttata aactaaaaca gctgatgata catattgcca aatacaaaat atctgatttc
    53521 tatacttcct ttacaaaaac caatccctgt ggttgtgaca aatcttctcg gtaaacaaat
    53581 ccagcaaagt tcaagcgacg tgcttccccc acagtttgta cttgattttc tattaaagct
    53641 gttagaaagg ccccgcgcgc tttcttggag atagttgagt gaatcttcag ctgaccgcct
    53701 ctatcctcca tgaatttgaa ggtcaccatc tttgctctga tttccttaga aaatacagtc
    53761 tcaaactctg atgacaagag agagaaaatc acttcttcct tcttcagagc ttcatcatag
    53821 actgccttcc aatggctctt caaagtctta ccagcgactt ttaatttcat caaaaaatcc
    53881 aaacggtgag gagccatggg tgacaaggct ggaacaacac cgtacaaagc cgaggtaatg
    53941 aagacatgat tttcaagata atcttgttcc gcctcggtca gcttatctct cttaatgttg
    54001 cggtacataa gcccatcaaa aagtttcaag gctggatagt gttgagcagt ttgccttttc
    54061 aaagcttgga tattttgaaa ttcttccgcc gctttctcag ccgatacctt gtagaaactc
    54121 tccaattgac tggcagaata gagagccaag gcatcaagca cggtctgact ttctggtttt
    54181 aaaggaattg cctcgatact tggcaagtct gtgttcattt cttttgctgt tgggattaaa
    54241 attttcatat tgatagtgta gcatattttt tagccacaac caagaaattc atttgaaaaa
    54301 cctcggtttg accgaggttt ttctatttat ttgggccatc ctaaccagac agccacgaga
    54361 acaagggctg tgccagctaa acttgttaag atagataaga atttatcttt tttctccttg
    54421 aactgagaaa aacctatctt caaagcgagc agtccgagta gcattgaagc aaccatcaaa
    54481 taaaaaccca tttctttgtc ctccattagg cttaatttac cttattataa catatattta
    54541 ttaaataaac cttttttata ctcaatgaaa atcaaagagc aaactaggaa actagccgca
    54601 ggctgctcaa aacactgttt tgaggttgca gatagagcta gagattttcg aagagtatta
    54661 ttgtacttta aaggtcttga gataattgtc ttttcctact tgaccttcga aggttttacc
    54721 attttcaagg taaggaaggt catcggatac tgaagccttg accttgtata tcttgccatc
    54781 aactttaaag aagtagacag tgtctccctt gataacagct gatttgaggt ctgctactac
    54841 tcccttgatg ctttctgtcg ttgcattgtc aatttcaagg tcgtttttat tggcatactt
    54901 gctgagcatc tcttccactg tagtagcaac gataacattt tggtactcga ctgcgtctac
    54961 cagggcgtac tctttgacca agccagcatt gtcctttaag cccatgatgt agagaggctt
    55021 gtcattgagg ttgatgagga ttgggaaggt tgctttgtag gatttctcct gaacagcacc
    55081 ttctgctgat tcacgggctg attcttctgt cgcagaagcc aagctatact tagtgatttc
    55141 tcctgttcgc atattttcaa ggatgaaacc aagattactc tcatccgcat tagccgacgt
    55201 cacacctgtg tagagataga tgtcattacc gatagacaag taattatagc ccttggtagt
    55261 ctgggtcaca tttttcttgg aaatcatggc attcaagaaa ccgtccttgt acttgccgtt
    55321 gtagttgatt tgctcaatgg tttcctctgc tggatagacc ctgtccaccc attctggaac
    55381 atctgataag ctgtattcct tggtttctcc atttgtagca tccaagataa tgactgaagc
    55441 aggacgagga accgcaagtc caaattgctt ttggtaaacc gttgctacat agaaaggatt
    55501 gccctcatcg tccacctcaa aagatggagt tttaaagatt ttagtcgggt acttcaagcg
    55561 caggtgacgt ttgacatcac ggttaaaata ctccgagtct gaatacttga ttggtgtctt
    55621 caagtccacc aaatccgcat ttccagttac catgtccacc ttgatatact caccgattcc
    55681 cttggcttga ttgttaaacc atttgatagg gtctgcatat tctagtggtg tgacccgata
    55741 aggtttccca tcaattgtca attgggtata ggtatctgcc gctacgtatt gcgacacctt
    55801 atcggttagg gaacccaagt agcggtctcc aattttttca gcagtacttc tatctaggat
    55861 aggaacctta ctggtgtcac tcctaggaaa ttcagtaaag tctttttccg taaccgtgac
    55921 tacattggca taatttttag cctgaaacat gctggaagtt accaaggaaa ccaaagctgc
    55981 caagagaaga attcctccaa tcgaagctaa cagaattttc cctaaccgat tgattttgaa
    56041 accctcaaga tttaaggcag cttccgcctt accgtggcgc acatgaaccg ttttgacaag
    56101 gtttatcccc ttgccaaagc caaataagat tgccacaact aacaaatgcc cacagaggaa
    56161 gaagagaaat tcccagctgg tcaggttaag gggcggtaaa aagatatacc aggtcgttgc
    56221 gataaaaata agttcaaaga ctattcgttt catttgcttt cctcctaaat gattcgtcct
    56281 tccaagtgat ccagctcatg ctggcaaatc tgagctggga agcctgtcaa ggtaatggtc
    56341 tgttcctgcc acttgctgtc acgataggca agccttatgg tttcataacg cttagttgat
    56401 ctcacaccta ccaaggacaa acagccttct tctgcctcat aagatccttc aaaggacaga
    56461 agcactgggt taaacatgac cacgggaacc aagccaagat taaagataat cacgcgcttc
    56521 tgcaccccaa tcatattggc agctagacca acacaggtat cacgatttgc taagagtgta
    56581 tcctgcaaat ctctggcaag ataaaggtcc tcctgacttg ccggctgaga cacttgagat
    56641 aaaaataaga tatccttcac aattttcttt tccacttcct cacactcctc ttgcttttta
    56701 ctatattata gcaattatag cacaaaagcc gataactgca aaccctttcc ctcaactgta
    56761 gcaaaaagcc atccgaagat gacttttttg ctatttaatt tctgtataag ttacttccaa
    56821 tccacgctta acagctggac gattggcaat tttttctgcc cattttacta gattttgata
    56881 acttgaggca tccaaaaatt ttgcagaacc ttggtaaaga tttccttgaa ctaactgtcc
    56941 ataccaagac cagatagcaa tatctgcaat cgtatagtca ttgcctgcaa tataaggttt
    57001 ctgagccaat tccttatcca ataaatccaa ctggcgtttc acttccatcg taaaacggtt
    57061 aataggatat tccaattttt caggagcata attgaagaaa tgtccaaatc ccccacctag
    57121 aaaaggtgct gcacctgctt gccagaatag ccaattcaaa acttctacct tttccacagg
    57181 attacttggt aaaaaggctc caaatttctc agcaaggtaa agaagaatat gagcagactc
    57241 aaagactctt acgttttcag tacctgactg gtccaataag gctggaatct tggaatttgg
    57301 attgagcttc acaaagtctg agccgaattg atccccatcc atgatagcaa tcttatacaa
    57361 gtcgtaagcc gcttccttaa aaccagcttc tagtaattct tccaataaga tagtaacctt
    57421 cacaccattt ggtgttccca gtgaataaag ctgaaaagct tgttctcctt ttggcaagtt
    57481 ttgttcgaaa cgggcacctg ctgttggtct gtttaacccc gtaaaagctc cttgattact
    57541 agcttcatcc tgccatacgg tcggtaattg atatgctgac atccgaaacc tcccttaaat
    57601 cgcattcttg tcaaaaccga gtttgcgttg aataaactta acgatttcga cgatgataat
    57661 cattgagaag cttccagcca taacaattcc ccattgtgac aagtctagtt tggttacgtg
    57721 gaagattcct tcaagcggtt ctacaacgat tgttgccatg agaaggataa aggataccaa
    57781 gatggaccag ttaaaggtct tagacttgaa tgggccaact gtcaagatgg attggtagac
    57841 agacttgaca ttgtaggcat ggaagagctg aatcaaacca agggttgcaa aggccatcgt
    57901 tagggcatct gcatgaatag catgattgtc acccacatga actgggtaag caatcgcaag
    57961 gccataaaca ctcataacaa gagctgcttg gagtacacct tgataaatga tagaactcaa
    58021 aacaccacct gagaagaagc ttgccttgcg tccacgtggt ttatgattca tgacaccagg
    58081 ttccgcaggt tcaacaccta gtgcaattgc tgggaaggta tccgttacca agttaatcca
    58141 caaaagatga actggctgca agacgtccca accaaacaag gttgatagga agatggttaa
    58201 tacttcagca gtattggcag aaagtaggta ctgaatagtc ttttgaatat ttgagaagac
    58261 cttacgtcct tcttccactg cgacgataat agtcgcaaag ttatcatctg caagaatcat
    58321 atcagaagcc cccttagaaa cctctgtacc agtgattccc ataccgatac cgatgtctgc
    58381 tgttttcaga gctggggcat cattgacacc gtcacctgtc atggcaacga ccttaccttg
    58441 tttttgccaa gccttgacga tacgaacctt gtgttctgga gacacacggg cataaacaga
    58501 gtattgacca acgacttttt caaattcttc atctgacagt tcattgagtt cagcaccagt
    58561 taaaacgtga ccttctgtat cgtttgcgtc aatgattccc aaacgtttgg caatggcttc
    58621 cgctgtgtct tggtggtcac ctgtaatcat aattggacgg attcccgctt ccttagccac
    58681 acgaacagcc tcagcggctt caggacgttc agggtcaatc atcccaatca aaccagtaaa
    58741 aattaaatca ttttcaagct cttcagaagt gagattttct ggaatactat cgataatctt
    58801 ataagcacct gcaaggacac gcaaggcttg atgagccatt tcagaattgt ttgtatgaat
    58861 gagatttgta accttctcat caatcggagc aatatcccca gccttatcac gaagaagaca
    58921 acgttttaag agttggtctg gcgcaccctt gactgctaca aggaaacgac catctggcaa
    58981 tgggtgaact gttgacatga gcttacggtc agagtcaaat ggcaattcag ctacacgagg
    59041 atatttctct aagaaacctt tgacatcata gcccttgtcc aaggcatatt ggataaaggc
    59101 tgtttcggtt gggtcaccaa tcaagttacc ttccacatcg attttcgtat cattggccaa
    59161 gacaactgaa cgaagtagtg gcatttcaag acctagttca atatcatcag ctgagtcatg
    59221 tagaaccgca tcgtagaaga ctttttcgac tgtcatcttg ttcatagtca gcgtaccagt
    59281 cttatcagaa gcgatgattt cagttgaacc aagtgtttca actgctggca acttacgaac
    59341 gatggaatgt cgtttggcca aaacttgagt accaagagaa agaacgatgg taacgatagc
    59401 aggaagtcct tctggaatgg ctgcaacggc aagggcaaca gaagtcaaca actcaccaag
    59461 tggatttttc ccttgaatga agacacccac tacaaaagta acaagggcaa tgaccaagat
    59521 agcataggtc aagaccttag aaaggttgtt caagttttgt ttgagtggtg tatcagtctc
    59581 atccgcatct tgaagcatac cagcaatatg accaacttca gtatacatac ctgtattgac
    59641 aacaacaccc atcccacgac cataggttac gtttgagttt tggaaggcca tgttgacacg
    59701 gtcaccaata ccagcatctg tcgcaagctc gactgacaag tctttttcga ctggtacaga
    59761 ttcacctgtc aaggctgctt cttcaatttt aagagagttg gcttctatca aacgtaggtc
    59821 cgctggtacc acgtcacctg cttcaagggc aacgatatcg cctggtacca attctttaga
    59881 gtcaatctct gccatgtgtc catcacgaag aacgcgggca actggactag acatggattt
    59941 gagggcttca atagcttctt cagcttttcc ttcttggtaa acaccaaagg cagcgttgat
    60001 gataaccaca gctaggatga taatggcatc tgcgatatct tccccaccag aagtcacgac
    60061 tgacaagatt gctgccgcaa ctaggatgat aatcatcaaa tccttaaatt gctcgatgaa
    60121 tttgaccaag attgatcgtt tctcgccttc ttcgagttca ttgtgcccaa attcggcaag
    60181 gcgcttttcc gcctcacttg atgacaaacc ttgctcggtc gcatccacag cctgcaagac
    60241 ctcttcaggg ctctgagtat aaaacgcttg gcgtttttgt tcttttgaca tgtgtctcct
    60301 ccttgacatt gtgtgcaaaa cagactctct ttctgtcata tcttttcacg acaaacaaaa
    60361 agagacctgt taatcataac aagtctcgct gtttaagata gggccggaaa gcatactttt
    60421 cagcataaaa ttcggaatga cgacactatc acaggtttct gccagctact cccttgagta
    60481 gtaccattat accaaatttt ggggagtttt caaagaataa aaactgcctt atttgaattt
    60541 ttccttgaaa accagtataa tggtagaatg ctatgtgact agaaaggaag ttgaatgaag
    60601 caatctatct caaatctcaa gttagccgag cgtggagcca ttatcagtat ttcgacctat
    60661 ttgatcttgt ctgcagccaa attagcaact ggtcatctcc ttcattcatc cagtttggtg
    60721 gccgatggtt ttaataacgt atcggacatc attggaaatg tggccctctt aatcgggatt
    60781 cggatggcgc gccagcctgc agaccgtgac caccgttttg gtcattggaa gattgaagat
    60841 ttggcaagct tgatcacttc tatcatcatg ttctatgtcg gtttcgatgt tctaagagat
    60901 accattcaaa agattctcag tcgggaagaa acggtcattg atcctcttgg tgcaactcta
    60961 ggaatcattt ctgcagcgat tatgtttgtg gtctatctct acaatactcg cctcagtaag
    61021 aaatccaact ccaaggcgct gaagacagct gctaaggaca atctttctga cgctgttacc
    61081 tcacttggaa ccgccattgc catcctagct agtagtttta attatccgat tgtggataaa
    61141 ctggttgcta ttatcatcac tttctttatc ttgaagactg cctatgatat cttcatcgag
    61201 tcttccttta gtctttcaga tggctttgac gaccgcctgc tcgaggacta ccaaaaggct
    61261 atcatggaaa ttcccaaaat cagcaaggtc aaatcgcaaa gaggtcgcac ctacggtagc
    61321 aacatctacc tggatattac actagagatg aatcctgact tgtctgtttt tgaaagccat
    61381 gaaatcgcgg atcaggtcga gtctatgctg gaggagcgtt ttggcgtctt tgataccgat
    61441 gtccatatcg aaccagcacc tatccctgag gatgaaattt tagacaatgt ctataaaaaa
    61501 ttgcttatgc gtgaacaatt gattgaccaa ggaaaccaac tagaagaact cttgactgat
    61561 gattttgtct atattcgcca agatggagag cagatggata aagaggctta taagaccaaa
    61621 aaagagttaa attctgctat caaggacatt caaattactt ccatcagtca aaaaaccaaa
    61681 ctcatctgct atgagttaga tggtatcatc cataccagta tctggcgtcg ccacgaaacc
    61741 tggcaaaata tctttcatca agaaaccaaa aaagaataga gaaatccttt catgagacgg
    61801 gatttttcta ttcttttata ctcaataaaa atcaaagtgc aaattaggaa gccggtcaca
    61861 ggctgtactt gagtcggcaa tgtgaagccg acatagtttg cactttgatt ttcgaatagt
    61921 cttaactatc aaattcactg agatactcat agcgttcgta tttttcaagg agtgcttcat
    61981 ttttctcatc caattctttt tggagagtag ccagcttacc aaagtcagag ccgttagcct
    62041 gcatttcctc ttcaatagca gcgatacgtt tttccaaggt ttcaatatca ccttcaatac
    62101 ttgcccactc ctgcttttct tggtaggtca tgcgtttctt gtcttctcga accttgacca
    62161 ctttttcctt ttcggccttt tgcacttgat tggccatatc tgtttcaaaa gctttttcat
    62221 caagatagtc ggtgtaatga ccaaagaaag gacgaatctt gccatcctca aaagcgagaa
    62281 tcttggtcgc taccttatcc aagaaatagc ggtcgtgact gactgttaaa acgggacctg
    62341 caaaaccttg caagaaattc tctaagactg tcaaagttgc aatatctagg tcattggttg
    62401 gctcgtctaa aagaagaaca tttggttttt ccaaaagcag tttgaggaga taaagacgtt
    62461 ttttctcacc ccctgacaat ttctcaatca aggttccatg cgtcgaacgt gggaaaagga
    62521 actgctccag caactctgca atcgaagtcg tagaaccgcc actggtcttg acctcttctg
    62581 ccacttcctg caagtaattg ataactctct tgctttcatc caaaccctca atttgctgag
    62641 agaaataggc gatgcgaaca gtttccccaa tcacaacttg tcctttagtt ggctcaagac
    62701 ttcctgcaat caagttgagc agggttgatt ttccaacacc attgtcccca acgattccga
    62761 tacggtcttt ggcctgcacc aagagattaa aatcttgcaa aataggcttg ttttcatagg
    62821 caaaggaaac agcctgaaac tcgatgactt tcttcccaat ccgactggtt tcaaagttca
    62881 tggtcaagtc tgtctcagca ctactgcctg aaacttcctt tttcagatca tggaatcgat
    62941 tgatacgggc ctgctgcttg gtcgcacgcg cctgcggttg tctgcgcatc caggccaatt
    63001 cttgtttgta gagttgttct tttttgtgaa gaagagccgc gtcgcgctca tcctgttccg
    63061 cctttaggcg aacatagtcc tggtaattgc cctggtactc ggtcaagcct gcacgatcca
    63121 actcgaaaat ccgtgttgac aaagcgtcta agaaataacg atcgtgagtg ataaaaagga
    63181 cggtcttctt agaatttttc aaaaagaggg tcagccactc aataatcgca atatccagat
    63241 ggttggtcgg ctcatccaaa agcaagaggt cgtggttgcc aagtaagact tgtgccaact
    63301 gtacccgtct tctcagacca cctgacaatt ccccaacagg agtagataag tcttgaatgc
    63361 ccaatttgct aagaacggtc ttgacctgac tttcgatttc ccaagcttgg agagagtcca
    63421 tctctgccat gacacgttcc aaacgcgcct gcttgtcctc actatagtcg agcataatca
    63481 attcatactc acgaatgagc tggatttcct tgagttcact agatagaacc gtatccaaaa
    63541 ctgtctttct atcatcaaaa tcaggatcct gagtcaagta accaatctgg taatcatttt
    63601 tagctgaaaa aggactgaca tccccatcaa atccagaaac accagaaagg acgtccaaaa
    63661 gggtggtctt gccagtccca ttgacaccga ttaaaccaat tctgtctaag tcatggataa
    63721 taaaggaaat atccctaaaa acggtcttgt caccaacgga tttacttagt ttttcaacga
    63781 taaaatcact cattttttct ccctcaggta agcatggatg gcttcacgat tattctccaa
    63841 ttctccatcg acaatggcaa actcaatctc tgttaaaatc tctcccaagt ctgggcctgg
    63901 ctgatagcca tattccttga tcaaaatacc gccattaatc tgaatatctt tcttgtcatg
    63961 gatagtcaag ctttggtatt tttctgtgat ggcttgtggg ttgacttctt ttccttgagc
    64021 ttgacgaaga ttttcagcct gtaaaagcaa atctatgtca aagcgataac aatctcgctt
    64081 gctcaattct ccattttcac gcagagccaa aataatcagc aaatcctgaa cttgcttggc
    64141 aaactggcgt gaggtcttcc aagatttcaa aaatgactgc gcattttcaa tctccaaagc
    64201 ccatagtaaa gccgcccagg cttgttcaga ggattcaaaa gtaaaatcag tctccaaatc
    64261 aaacagtctg ttgagcttgt cctggctaga tgccatatca gggagatagt cataagcttg
    64321 actctcaatc atggaagcca agccccttct ccaaaatgga gccagcaaga gtttatcaaa
    64381 ttcgacgaag gtacgctcta cagaaatttt ctccaaaagc ggcgtcaagg tcttcatagc
    64441 tttaaatgtt tctggctcaa gtgcaaaacc aagactagcc tgaaaacgga aaccacgcat
    64501 aatccgtaaa gcatcttcgt tgaaacgctc actagccact ccaactgctc gcaagacttg
    64561 cttttccaaa tcttctaaac catggaacaa gtcaacgatt tctcctgtct catccaaggc
    64621 aaaggcgttg actgtgaaat cacggcgttt gaggtcttct tctagcgagc gcacaaagga
    64681 aaccgcactg ggtctgcgat agtccacata gacatcctct gtccgaaagg ttgttacctc
    64741 atactcctca tccccatcta agaccaagac ggttccatgc tcgattccga tatcggctgt
    64801 tcgcggaaaa atctgcttgg tctcttctgg ataagaagac gtcgcaatat ccacatcgtg
    64861 gatagggcta tggagaaggg catctcgaac agagccccca acaaaataag cctcaaagcc
    64921 tgcttcttta attttttcta atactggtaa agccttctga aattcagaag gcatttgcgt
    64981 taatctcata ataagtgttc taatccatag acaagctcat gacgcttgac aacttcttta
    65041 attcccaaat tgactcctgt catgaaggag atgcgatcat aggagtcatg acggagggtc
    65101 aacccttctc cctgattgcc aaagatgact tcctgatgag ctaccaagcc tggcaaacga
    65161 actgagtgga tgcgcatacc atcaaagtca gcaccacgag caccagcaat cagctcttcc
    65221 tcatctgctg caccttgctg aattgactct cgaacctctg ccatcaactc agctgtttta
    65281 atggctgttc cactcggagc atcctttttc ttgtcatgat ggagctcaat aatctccaca
    65341 tttgggaaat atttggcagc ctgcgtcgca aattgcatga gtaagacagc acccaaggca
    65401 aagttagggg caatcaggcc acccaagtct tgggcacgag aaaattcttt tagctctgca
    65461 atttcttcac tcgtgaaacc agtcgttcca actactggag caaagccatt ttcaagagca
    65521 aaacgtgtat tttcgtaggc aacagctgga gtagtaaaat ctatccagac atccgcttca
    65581 aaaccagcta aatcagcctt atccttgaaa acaggaatac cctgccattc tggctcagac
    65641 tcaaaaggat ccaaaactgc taccaagtcc aagtctggat cagtcaatac catctgacaa
    65701 gcagcctggc ccatctttcc cttaaaaccg gcaataatta ctcgaatact catctctact
    65761 cctgtccaaa atacaaagcc tgtaagaaca caaagtgaaa ataggaattc tgatcaagaa
    65821 gtgtctactt cttggaagaa ctatcttttt cacacagggt tccaggcgtg ttcaattatc
    65881 aagatacaaa ggaccttagc tgcccctgaa aaatagggaa tggcactgac tttccacgaa
    65941 aggcaagaca ggcatctttt ttcaagaggc aggtagtccg tgttcaattt ctaagattaa
    66001 ctagcctaga agtgccaact aaatcactgg aatataacct agagcaatac ttcctgctcc
    66061 taggtgcgtt ccaatgacac taccaaatgt agcaagtgaa acatccgaac ccaagccaaa
    66121 atcaagcaaa tgctgacgca attcttcagc cttttcagga gcattcccat gaatgacaat
    66181 gacccggtat tgacctgaag ccgttgtttc cttgataatt tcaattaagc gtttggtggc
    66241 cttcttttca gtacgaactt tttcgtaaac ttcaatcaca ccttgatcgt taaaataaag
    66301 gattggctta atgctaagca aattgcccaa aatggcagcc ccatttgaaa ggcgtccacc
    66361 ttttaccaaa tgatccaagt catctaccat gataaaggct gacgtacggc tgatttgaat
    66421 ggctagctta tcctgaatgc tggcaaaatc atcgccctga tcacgccaat taaagacgct
    66481 ttcaaccatg atgcctaggg gagcacttgt aatcaaagtg tctgggaaag caatggttaa
    66541 gccctcatag tcatcgacca tatactggat attttggtaa aaacctgaaa ttccagaaga
    66601 taggaaaagc cccaaggcat gtgtatagcc ttgttctttg agcgaagtta agatttcatc
    66661 taacttggca atacttggtt gactggtctt aggcaattca gaagcctgag ccattttttg
    66721 gtaaaattcc tcagcagaca gattgatgcc ttcgacatat tcctcaccat caatattgac
    66781 aggaatatcc aagacaaaca agtcttctct ttgcaagatc tctgcactga gataagcaga
    66841 ggaatctgtg aaaacagcta atttcatatt agaactccaa attaattcct ggtaagtcta
    66901 atgcaatttc agtcacttcg taagtcaaac gattgagcat gttcaaacat ggacgagcca
    66961 aggtttccac ctcttcttgg ttcaattcac ttggttcatt gacaatacgg ccatcgatat
    67021 ggtttacttg tgagattgtt ccactaatga caaacttatc aaatacaatc ataaagctca
    67081 agatgacaat caaggaagtc acttgatttt cttggtcatg ttggagcaat tggaaattca
    67141 catccacctt ggtttcagga gctccatttt cattttccca ttcaaaatta cgcgcatcaa
    67201 aatgatactg actaacaaat tcttgttcac gtttaagatt catgtctttc tccatcggct
    67261 acaatattat aagctattgt accataattt tttattttca tctagttttc taggatttag
    67321 tcaatcccaa tttcagcacg aactacatct gtgatggtat caacatagta gtttacttct
    67381 tctgttgtag gcgcttctgc cataacacgc aagaggggtt ctgttccact tggacgaaca
    67441 aggatacggc cgttccccgc catttcttct tccatcttct cgatgatggc cttgatagct
    67501 ggcacttcca tggccttttc cttcatgacg ttttccactc ggatattaac taatttttgt
    67561 ggataaatcg ttacttctgc cgccaactct gataagctct taccagtttc cttcatgatt
    67621 ttagtcaatt gaactgctga taattgacca tcacctgtgg tattgtaatc catcaagata
    67681 acgtgaccag actgttcacc accaaggttg tagcctgatt ttctcatttc ttcaacaacg
    67741 tagcggtcac caactgcagt aactgccttg ttaatacctt cgcgattcaa ggccttgtgg
    67801 aaaccaaggt tagacataac agttgtcaca attgtatttt gagccaattg tcctttttca
    67861 gaaaggtatt ttccgatgat gtacataatc ttgtcaccat caacgatgtc accattctca
    67921 tcaacagcaa tcaagcggtc actgtctcca tcaaaggcca aaccaatagc tgacccactt
    67981 tctttgacca cttcttgaag ggcttctgga tgtgttgaac caacattaag gttgatgtta
    68041 agaccgtctg gtgtttcccc gataaccgtc aattgggcac caaggtctgc aaagatttga
    68101 cgggcactgg tagaagctgc tccattagct gtatccaagg caaccttcat tccatcaaga
    68161 ggagttccag ttgaaacaag gtatccttca tacttacgca agccttctgg ataatctacc
    68221 aaaattccta agccttctgc acttggacga ggaagagtgt cttcctcagc atctagcaag
    68281 gcttcaattt ctgcttcttt ttcatcatct agtttgaagc catcaccgcc aaagaacttg
    68341 attccgttat caagggctgg gttgtggcta gcagaaatca tgacaccggc acttgctcct
    68401 tcagtttcaa ccaagtaagc tactgctggt gttgcaagga caccaagttt gtatacgtga
    68461 atccctactg aaaggagacc tgccaccaag gccgattcca acatttcccc tgaaatacgt
    68521 gtgtcacgtc ctacaaagac tttcggcgct tccgtttcat gttgactaag aacatagcct
    68581 ccaaaacgtc ctagtttaaa ggctaattct ggtgttagtt ctaggttagc ttctccacgg
    68641 actccatcag tcccaaaata tttacccatt gttataaaat ccttttctat ttttaattcg
    68701 tttttgaact agttgctttc gttgacgaag atgtctccga tgaactgctt gtacttgaat
    68761 ttgatgtgct tgaacttggt gctactggtt ttgtagtcac cttcattatt gtatcaaacg
    68821 gagtgataac tgccggtaag acaacaccat tgcggtcgat tgcctgcaaa ggtactgaac
    68881 cactgtaatt acctgttata cgttcgctag ttggcaaaac agcgataatc ttatcaattc
    68941 tatccaatgt ctcttggtca ctcgtaatag acacttcttt atctgacacc atgacatttt
    69001 caatttgtac ccgactatca atttgactag ggtcaatctc tggtacaatc tttaccttat
    69061 ccttctgagc cttcttacca atcttgactg taattttttg cggagtcgcc acagcggtca
    69121 gcccattggg taaatcttca atgctcaaag gaacttcaat cgttccaaca ccggcatctg
    69181 ttaggtcagc agtaaccttg aatttacgtg tactttcttg catttcacta gctagcgata
    69241 ggcgatttgc accagtcaag accactgata cttctgaagc aaaaccgcta ataaaatact
    69301 tatcactatt atagcgtatg tcaataggga catttgttac tgtattagta taggtttccg
    69361 tttttacctg cctagcactg gtactgtttt gaaaattcgt cgccgtagca tagacaaata
    69421 agacacaagc aaaaaagagt gaggatatga tatataaact attttttttc atgtttccat
    69481 cctcctagca atcgttcttt aaaactaaga cccacttcct cttttggaag taagatttca
    69541 cgtaattctg tttcaaattc atcaagtgtt aggttgtgct taaaccttcc attataggtt
    69601 atcgaaattc ctcccgtttc ctctgatacg acaaaagtca aggcatctga gacttctgat
    69661 aaaccgatag ccgcccggtg tctggtccca aattccttgg aaatccctgt gttttttgtc
    69721 aagggcagat aggcagacgt cacagcgata cgttcttctt tgataatcac cgcaccatca
    69781 tgtaggggag tgttgggaat aaaaatgtta atgagaagtt ctgcagaaat cttagcatcc
    69841 aagggaattc ctgtcgaaat atactcctgc aaggtacgta cacgctgaat agcaaccaag
    69901 gccccgattt tacgaggact catgtattca acagacttaa caaaggcacg aatcatctgt
    69961 tcctcagcac taataggggc attggaaaag aaatctgtcg ctcttcccaa acgttccaaa
    70021 ccagtccgaa tctctggaga gaagataaca accgccgcaa taaccccata agtaataatt
    70081 tgattgatta accaagaaat cgtagtcaaa ccaatcatat ttgcaaggat ttgagctaaa
    70141 ataaacacca aaactccacg taccaaaatc ataatcttgg ttcctgcaat agcttttgta
    70201 aaatggtata aaatataagc aacaatcaaa atatcaatca gattgatagc tatcgtccat
    70261 ggacttgcaa acaaactggt ccaatattgc agattggata attgttgaaa attcatccct
    70321 gatatcctcc ctatcaaaac actttcgtcc tattatacca ttttctggca tttttttccc
    70381 tatcctagtc cattttacat tgaacaaaaa tatgataaaa taaactgact aaaaaaaaca
    70441 aaggagaaac tatgtctcaa ctctatgata ttaccattgt gggtggtggt cctgtcgggc
    70501 tttttgcagc cttttatgcc cacctacgcc aagccaaggt tcaaatcatc gactctcttc
    70561 cccagctagg tggacaacct gctattctct accctgaaaa ggaaatccta gacgtaccag
    70621 gcttcccaaa cctgactgga gaagagttga ctaaccgctt gattgaacag ctaaatggat
    70681 ttgatacccc tattcatctc aatgaaacgg ttcttgagat tgacaaacaa gaagaatttg
    70741 ccatcacaac ttctaaagga agtcacctga ctaaaacagt tatcatcgct atgggtggcg
    70801 gtgccttcaa accacgtccg ctggaacttg aaggggttga gggctatgaa aatatccact
    70861 accacgtttc taacattcag caatacgctg gtaagaaagt gacgattctt ggtgggggag
    70921 actcggctgt ggattgggct ttggcttttg aaaaaatcgc accaactacc cttgttcacc
    70981 gcagagataa tttccgtgcc ttggaacaca gtgttcaagc cttgcaagaa tcatctgtaa
    71041 ccatcaagac accattcgcc cctagccaac tccttggaaa tggaaaaaca cttgataaac
    71101 ttgaaatcac aaaagtcaaa tctgatgaaa ctgaaaccat tgacctagac cacctctttg
    71161 tcaactatgg tttcaaatct tctgtcggta accttaaaaa ctgggggctc gacctcaacc
    71221 gtcacaagat tatcgtcaac agcaaacagg aatccagcca agcaggtatc tatgctatcg
    71281 gtgactgctg ctactatgac ggaaaaattg atctgattgc gacaggcctc ggagaagctc
    71341 caactgctgt caacaacgct atcaactaca ttgaccctga acaaaaagta caaccaaaac
    71401 actctactag tttataaaaa agaaccacga gtcacatagg attcgtggtt ttataattca
    71461 tccgctatct tattgatttt tctgagtctg tgattgacac cacttttggt cagaggggtg
    71521 ctgaggctat ctgccaactg ttggatagag tagtctgggt gctgaatcct cagttgcgcc
    71581 acttcctgca aatctactgg caaattttct aagcccatga tatcttttat tttactgata
    71641 ttgttaatgg tcttcatgct ggcagaaact gtccgagcga tattagctgt ctcggcatta
    71701 ttagcccgat tgagatcgtt acgggtttct cgcaaaatct taacccgctc aaaatcatca
    71761 cgtgcctgca tggctccgat tactatcaag aagtccataa tgtcttctgc tcgctggaga
    71821 taggtcacag cccccttctt gcgctcaagc accttggcat ccagtaaaaa ctgttggaga
    71881 agggaggcaa ttccttgcgc gtggtccaga taaacagaac tgatttccaa ctggtacttg
    71941 cctgactcag ggtcacgaat gctcccattt gccaagaaag cgccacagag ataggcacga
    72001 cctgcttcct cgtccgataa aatcgcctca tcaatacctg tttccaggcc aaagaaagag
    72061 tctgccaagt gcaaatcact taacaaatcc tgcacctttt catctgtaaa aacggtatag
    72121 acgcgattct tgcgaagatt gctccgttgg tggtgacgaa tttcagattt gatttcatag
    72181 aaatggagaa aggactcata gaggtgacgg gccagtttgg cattttctgt cacaactgac
    72241 aaagtcaagc ccgaagtcga gagaccgatg ctaccagaca ttttgataat ggcagataat
    72301 tcatgccggc tcagatggtg ttggcccagg atttcttctt ttactgctac tgtgaaactc
    72361 attttttcac ctgtataatg cgcatcaact cgtccacaat caaatctcca tcgtggaagg
    72421 caccgccatt ttccagacga aggaagttag atgaaatcac gcgcgaaact tgcttacaaa
    72481 gacctacaaa atcgtgttcc acttgcacca agtattcatc aaaacggttg gaattcatgt
    72541 attcctgagg cactttttca atatttacca agacagtgtc gataaaaggg cgaccaaggt
    72601 gacgatgcaa gacttccacg tggtcgctat ctgtaaagtg ttccgtctcc ccacgttggg
    72661 tcatgatatt gcagacatag gcaatttctg ccttagtttc caaaagagcc cgcccaattt
    72721 ccttaatcac gatattgggc aaaatagagg taaagaggga acctggccct aggacaatca
    72781 tgtcactttc aaggatggtc tgcactactc gacggctggc cagaggcgta tcatcgttta
    72841 gggcattggt cacatagaca ttgtcaatta tgcctcgatg gtctacaata tgactctctc
    72901 cagccacttc tgtcccatcc tgaaagactg catgaagggt caaaggatgg tcactggaag
    72961 gataaatttt ccctgttgta tggaaaaatt tgctcaataa ctgcatggca ttataggttg
    73021 aaccctgcat ttctgacaag ccagcaatga tgagatttcc caatggatgg ccagcaaagg
    73081 ctccggcatc ctcagagaac cgatactgaa agaccttctc ataaaactta ggcatatccg
    73141 acatggccac aaggacatta cgaagatcac ctggcggtgt caactgttgc atattttttc
    73201 ggagttcacc tgaagaacca ccatcatctg ccaccgtcac gatagctgcg atttccacat
    73261 ctttttcccg cagacttttt agaatgacgg gaattccagt ccctccacca atcaccgtta
    73321 tctttggttt tctcatgaac ggtttaccgt ttcctttctg cggtctttgt cgcgatgccc
    73381 ttcattaaca gaccaattct tggataagtc ctgcgccaag cgtttagcaa atgccacact
    73441 acggtgttgt ccacccgtac atcccatagc aatggtcaaa acggacttac cttccttttg
    73501 gtaacttggc agaatcggct caatcaaggc caataaatgt tgataaaagt cttctgactc
    73561 aggatggttc atgacataat cataaacagg ttcatccaca cccgtttggt ttctcagttc
    73621 tggtagataa tagggatttg gcaagaaacg gacatcaaag accaagtccg catcaatcgg
    73681 gattccatac ttaaatccga aagacatgac ttcgatacgg aaagactggg cttgttcttg
    73741 gtctgaaaac tgctctgcaa gggttttacg cagctcacgt ggagtgagtt cagtcgtatc
    73801 caccacattt tggctcatat ttttcaaagg tgccaagagt tcacgttcca acttgattcc
    73861 atctaaaata cgaccgtctg ctgctagtgg gtgactccgt ctggtttcct tgtaacgagc
    73921 gaccaattcc ttatcagccg catccaaaaa gaggattttg aaatctaaac catcttgatt
    73981 ttccaactca tccaaaacag cttgaatctc tgaaaagaaa gaacggctac gcatatccac
    74041 taccaaggcc aacttaggat tgtcttcctt aatttcaacc agctgcaaaa acttaggcaa
    74101 gagagctggc ggcatattat caatggtgaa ataacctaga tcctcgaagg actgaatggc
    74161 tacagttttc cctgcgccac tcatccctgt cacaatcacc aagtgaagtt gtttctttgt
    74221 catctttttc tccttatatc aaaagaagtt tggcaacacc aaacttcaac tagcttatcc
    74281 aatctctgcg atgacttcaa tttcgacttt tacatcacga ggaagacgag ctacctccac
    74341 agctgaacga gctgggaatt cctctttgaa ggccgtttgg taaacctcat taaaaggaac
    74401 aaagtcgttc atatcgctca agaagcaagt tgttttgaca acatggtcaa agtctgttcc
    74461 tgcttctgcc aaaatagcac cgatgttttt caagacttgc tctgtctgtt cttggatatt
    74521 ctctcctaca atttccccag tttcagggga taggggaact tgaccgctag caaacaaaag
    74581 gttgccaacg atttttcctt gaacataggg tccgatagcc tttggggcct tatctgtatg
    74641 aattgttttt gccattttct tttcctcaca atttttctaa gattgcatcc caagcctcat
    74701 ccatccctgc cttgctgaca gatgaaaaga ggatgaaatc gtcacttggg tcaaagttta
    74761 atttcttttt gattgctgat tcatgcttgt tccatttacc acgaggaatc ttgtccgcct
    74821 tggtcgccac aatgatgact ggaatctcat aatacttgag aaattcgtac atctgcacat
    74881 catctgctga cgggtcatga cgaaggtcaa ctagactgac aaccgcacgg agattttccc
    74941 gagtcgttaa gtactcctca atcatgcacc cccacttttc acgttccttt ttagaaacac
    75001 gagcatagcc ataaccaggc acatccacaa agcgcatctt atcatcaatg ttaaaaaagt
    75061 tcaggagctg ggttttacca ggttttcctg atgtacgggc gagattctta cggttcaaca
    75121 tagtgttgat aaagctggat ttaccaacat ttgaacgccc tgctagggca atctctggca
    75181 gttcatcctg cggatagtgg gacttattag ctgcactgag caagatttca gcattgtgtg
    75241 tattaagttc catagtcacc tctaggctgt ttctaggatc ggtttatccg ttccatcgac
    75301 agtttcttta gtgatgcgaa ccaatttcac attttcctga ctcggcacct caaacataac
    75361 atctagcatg gtttcttcga tgatggagcg aagtccacgc gcccctgtct tccgttcaat
    75421 tgctttatta gcaatctctt gaagggcttc gtcgtcaaat tctaactcaa catcatcata
    75481 agaaagcaag gtttggtatt gtttcaccaa ggcatttctt ggctctttca agatgcgaac
    75541 caagtcatca acggtcaatt gctcaagagc cgcaaaaaca ggcaagcgtc caatcaactc
    75601 agggataata ccaaattttt gaatgtcttc agcgatgatt tcttgcatgt atgagctgtt
    75661 tgcgtcaatc gccttattgt tttgaccaaa tccgatgact ttttcaccca gacgttgttt
    75721 gacaatttct tcaataccat caaaagcacc acccacgatg aagaggatat tttttgtatc
    75781 cacttgaatc atctcttgtt gtggatgttt gcgtccacct tgaggcggta cgctagcaac
    75841 agttccctcg ataatcttga gaagggcttg ttgcacccct tcaccagaaa catcacgtgt
    75901 gatagacaca ttctcactct tcttggcaat cttgtcaatt tcatccacat agataatgcc
    75961 acgctctgca cgttcgatgt taaagtcagc aacctgcaag agtttgagga ggatattttc
    76021 cacgtcctca cccacataac cagcctccgt cagagctgtc gcatccgcaa tagcaaaagg
    76081 tacattcaag ctcttagcca aggtctgggc aaggaaagtt ttccctgaac cagttgggcc
    76141 aatcatcaaa atgtttgact tctgcaaatc cacatcttct gactcttcgc gtgtatcgtg
    76201 gaaattgatg cgtttgtagt ggttataaac cgccactgcc aaggcacgct tggcacgatc
    76261 ttgaccaatt acatagtggt tcaagatatg gaggagttca attggttttg gcacctcaga
    76321 taagtctgcc aagacttcct caaccaattc ttctcgaatg atttcctgag ccaactccac
    76381 acattcatta cagataaagg cattgttccc tgcgattatt ttttgtactt cttcttggct
    76441 tttgccacaa aatgagcaat aaaccatcat atcattattc ctatttgtag gcatgatttc
    76501 cttccgttct attctatact gtcattctat ctaaaataag gtcatgtaaa aggcatggac
    76561 actatttacc agattggtaa aggcatttaa ccagagcagg acagaaagtc cataacgctt
    76621 tttacgaaaa gcctgtgctc ctgcaagcaa gcagaccaaa cacagcatgg ctgtgaaaaa
    76681 accaaatata ctacgttcca ttagacttcc tttctcttgc ggtattggat agtaaaatca
    76741 taaggatttt tctcatcttt ggcgtaaaat ttgcttgaaa ctatttcaaa aatagacaag
    76801 tcaaactctt caggaaaata ggtatctccc tctacccgag catgaatgtg agttacaatc
    76861 acttcgtcaa ggtaaggttc aaaagcctga aaaatttgct ttccaccgag aatataaaga
    76921 ttcttatctt gagcctgata ccagcccaag acagactgaa catcataaaa agtagtaacc
    76981 ccatctatct tttcttcaga attacgcgtc aaaatcaagg tctcccgttt tggaagcaag
    77041 cgacgcccca ttccatcaaa ggtcacgcgc cccatcaaga tggcatgatt cagagttgtt
    77101 tctttaaagt gctgcaattc tgctggcaaa taccaaggca gacgattgtc cttaccaatc
    77161 acaccctctt catcctgggc ccaaatagct acgattttct tagtcatgct tccatccttt
    77221 tcactgatag tactatttta tcaaaaaact caaaaaaaga ctggtttgga atagcttaca
    77281 gaatagaaaa aatccgtaag aggcatccta cagattttta tatgattatt ctatttctta
    77341 caaaccaggt gcttgtccaa gttctgccgc aagcatccag attgttttat cagtttcagt
    77401 cttagcgtct gcaaagatac cgtttgtcac atcgtcacct tcttcatcag tgacatccaa
    77461 acctttttgg aaaagttctg acaagtaacg gtagatagca agaacacgtt ccaagctttc
    77521 ttcaacatta cggtattcac cagcttcttc ttcgatttca ctattttgaa ggaactctgt
    77581 caatgtagag aatgggcttc caccgagtgt aatcaagcgt tcactgattt catccaattg
    77641 accgtcaaga gcttccatgt actcatccat ttttggatgc catacaagga aaccacgacc
    77701 atgcatatac cagtgcactt ggtgcaaagc aacgtgagct acatacaaat cagcaacagc
    77761 ttggttcaag acttcctttg tttttgccaa tgctactggc gctgcttttg tcaatgatgt
    77821 tacgtctttt actgcttctt ttttcaattc taccattttc tttacctcat tcattatttt
    77881 ttgtaaccac ttcttaatga ttactacctt agtatactac taaggaaaac caatagcaag
    77941 acaaagaact tatatgagaa aagttgcaat agactgataa tttaagaatt ctttagaaga
    78001 caaaaagagg gttggatgct tatagtcaat ggaaatccat cagcaaacta ggaaactaaa
    78061 cccagcttga ccaaagcaca agttttgagg tcgcaggtag aactgaccaa gctgatgtgg
    78121 tttgaagaaa ttccccaata ctataataga ttgaaataag atgaaaccaa gtcgattagg
    78181 aaaggtaaat gaatttctaa aatgttttac caatcacaag gtatttgtct atattcaatc
    78241 tactatataa gcttcatttc cgagcaagaa cttgaattta ctcgaggatg aactatcata
    78301 aaacaaagaa aaagagggtg ctactatcac atccctcttt caaatcatcg cttaatacca
    78361 aacgctgaca tctacgcgcc cttggattcc tttcatgtat tcagaagagg tatattgcca
    78421 accttttttt cctgaataat gagggttttc ccattctaaa gcattcgtat aggccgctac
    78481 ccagtttaca tgttttaaaa tatctgggtg ttttaaacgc gtctgtaata aactacgata
    78541 gctatagaca tacacatttt gataacccgc ctgcttcatc gtgtccatgt acttgttgat
    78601 gattttaacc caagtgcctg tatcacttgg agctctcttg ctcttattta catattccca
    78661 attctcaaca tcataataga tagggtaaga caggttcata ttgtatttct ttataagttc
    78721 aatggtctgt ttagcgtcac tctcagcatc ggtctcattt tcagcatagg tatagagata
    78781 gacaccataa ggaattccca gacggtttaa ctccttaatg ttatgcgcca attccttgtc
    78841 ttctttaccg ctataaccta gacgaacaat gacaccatcc acttcgttct catcaataac
    78901 ctttttccaa tcattgatac gaccattgtg ctcactaata tcaatgactt tcttagcatg
    78961 ttcggttccc acttgttctt ctctattatt aaagaaatag cgcttaccat ctctgtgaac
    79021 ccagccgaca ttcaaatctt ttttttcttt gagctcacca gaggccgcaa agatatagcg
    79081 agtaccatcc ataatcactt cgtcagtcgc catggcacca cttccagtca aatagtagtt
    79141 gccttgccac tcattccgag ccatatagcc ccacttcttg aaatagtacc atttgccgcc
    79201 cactttttgc cactcttggt tagcataagt tccatcggat tttagataaa aataagcaga
    79261 ataggctgga tcatagagcc attcattttg catcatagct ccttgaccat tcaagaaata
    79321 acttccttgc cattggcttt tagccatgta accccacttc ttgaagtagt accacttatt
    79381 tccaatcaat tgccattctt gatgagcata agccccatct gacttgagat aaaaccaact
    79441 cttgtaatta ctgtcataga tccactcgtt ttgggccata tatccacctg atttcaggta
    79501 gtaatttcca tgccattcat tctgcgagta acgaccatct gaattaatat aaaaccaagc
    79561 cttatagtag ttgtcaaaaa tccattcact ttgagcttta gaaccatcat cctttacata
    79621 ataatcccca tcccagtggg cagcagcatt agtctgtact tctgcgctcg tttgcgtttt
    79681 attagaagac tgattttgct ctgaactact tgaagctgtc gttgtatcct gcgaagtttt
    79741 tgctacttca gtttcatttg cagcgacatg actagttgcc aagcctagta aacagatact
    79801 tgctaatcca atttttgttt tcaatctttc tctcctataa aaaatgtaac agacatctga
    79861 atgctgttcc acctagcttt tgctacttac tgattatttt acaaagtcaa gcaaagccaa
    79921 gaagctttca gcttcaagtg acgcaccacc tacaagggca ccgtcaacgt ctgggcaagc
    79981 catgtatgaa gcaacatttt caggtttaac agaaccaccg tattgaacac gaactttgtc
    80041 tgcgacttct tgaccaaagt cagcagctac aacgtcacga acaactttac acattttttg
    80101 tgcatcgtct tgtgaagctg atttaccagt accgatagcc cagattggct cataagcgat
    80161 aactgaggca gcaacttgtt cagcagtcaa tccagccaat gcagcagata cttgagcacc
    80221 tacgaattca gcagctttac cagcttcgta agtttcaagt gattcaccac aacagatgat
    80281 tggaagcata ccgttcgcaa agattgcttt tgcttttttg ttgatatctt catcagtttc
    80341 atggaagtag tcacggcgtt ctgagtgacc gataacaacg tagtcagtac cgatttcttt
    80401 caaaacttgt gggctagttt caccagtgaa agcacctgca ttttcaaagt agcagttttg
    80461 agcagcaact ttaaggtttg agccttttgc aacagcaaga acagttgtca aatcaagagc
    80521 tggagcagcg atacctgctt caacaagatc tgatgaagga agttttgatg caactgcttc
    80581 aacgaatgct ttagcttctt ctggattttt gttcattttc cagttaccag cgataaatgg
    80641 tttacgtgac atttcacata cctctttttt caatttattt tctatttatt ctatcacaat
    80701 tatacacagc ttgcaaatct tactcggatt tcaagcctac ttgcatggat taatccttcc
    80761 agagatccat ggcatttatg aaatctgcag atacctgtgt caactgagga ttgcttgctt
    80821 ctctttctgc tctcttggcc tcaatttgag ccacactctt gattccttca tggcgccagt
    80881 ttctcaaaat cgcctgaatg tacttccagt ttggttttcc attcaaaaca gcttcacgaa
    80941 gagcctcctt aatcaagtca gcactggttc catcttcctt tagtgtcttg gtcaaatcct
    81001 caatctcaaa aggcgtcaac aatcgtccca actcctgctg gaaggtttcc accaaatcct
    81061 tgagctggtt ttgaggtgtt agctggtctg aacttgaatg aactgctcca aacaggtcat
    81121 ccaaacgttc caaggccaaa ctagcatcaa agagcaattc aatttcgcca tttaattcga
    81181 tagtacgata ctggagcagt cccctttccg tcagattaga aatggactgg ttgacatccg
    81241 aaatttcctt gccaatcctt tcagcaatct ggcttggcga catttcttct aagcctgtcg
    81301 tattttgcaa atagaaaaat tgccaaacca gaaaatcgtc gctagaagga aagagttcct
    81361 taaaatgcaa gagcagggca ctcggtaaaa ccaaggcacc tgatttaaaa gcgtctaaat
    81421 atgtcataat tcctcttata aatacccata tgcagatgca tcatcttcta tctttctcca
    81481 gtcaaaaggc gtctcctgat agaccgcatg gtttacccaa ttactgaaaa agagggctgc
    81541 agatgaagac caacaaagac aaggtacctg attaacatca tcatctttaa agtaattttc
    81601 tggaatatgt gggtcgaaac ctgcatcacg atctcgaaaa tactcttttg ccaaggtatc
    81661 acggtcatac tccaaatgac caaaactata aatttctcgt aaatcacgac tggccaaaat
    81721 agaaacccca acctgaggtc cttctgataa aatctcgaga ttggtcttgt ttaagacctc
    81781 ttccttagaa atctccgtgt gccgtgaatg aggagataca tagctatcat caaagcctct
    81841 aaatagaagg tgaccctctt ttagggtgtc ctgaggataa atacctgata gcttactgtc
    81901 catctggtat ttttctacac catagcgcag ataaagccca gcctgagccc cccaacagat
    81961 atgaagggtc gaatagacat gagtcttaga ccactcaagc atctgtctaa attcctccca
    82021 atagtccact tcctcaaatg gtaaatgctc aactggagca cccgtgatga tcatcccatc
    82081 aaaatactca tccttgactt caagaaaagt tttatagaag gtctccatgt gctctgaacg
    82141 agttgtttta gaacggtggc tctccatata gagaaaatca atatccagtt gtaggggtgt
    82201 attagccaag tggcgcaaca actgggtctc tgtgaccatt ttctgtggca tgagatttaa
    82261 aattaaaatc ttcaaaggac ggatatcttg gtgggcagca cgttgatcat ccatgacaaa
    82321 gatattctct gtccgtaaaa tctcaacagc tggcaatttt ttatcaattc gaatcggcat
    82381 aaccctctcc taactgtact ctttcaggaa taattgcata tgtttgaaga caaatctcaa
    82441 acacttagtc cttttattat actgcaagaa gatatagttt tcaattatag tttttctcta
    82501 actagttata gtctattttt atatcctagt gtagagaaaa cagccctagg gactgttttc
    82561 attaataatg cataagaact ttgtagtcgt agtcaccgat tttttcacgg ccgttcaatt
    82621 catccaattc aacaaggaag gcacaacctg ccataacacc accaagtttt tcaatcatct
    82681 cgatagttgc cttaacagtt ccacctgtcg ccaaaaggtc atctacaata agaacacgtt
    82741 gacctggctt aatggcatcc gcgtgcatag tcaaggtatc gacaccgtac tctttttcat
    82801 agtcagcaga aataacttcg cgtggcaatt tacctggctt acgaacaggc gcaaaaccaa
    82861 ttcccaactc aaaggcaact ggacaaccca cgataaatcc acgagcttca ggtcccacga
    82921 tcatgtcgac tttcttgtca gtagcatact gaacgatttc acgaacagcg tagctataag
    82981 catttccatc agccatcaaa ggactaatat cacggaaggt aatgccttcc tttggataat
    83041 tttcaattgt tgcaatgtaa tcttttaaat tcatcttttt ctttctttca aagtttttta
    83101 ctctctatta tagcatattt tttaagaaag aaaaaaggaa aagttaactt caataattat
    83161 ctaacgtttt gacgatttat aactagccat cgcaataaaa cccaatttct gtttattctt
    83221 agcaaacatt ttatacatag ttaaaaactg ctttctattc tcctttttac aagcatttac
    83281 acaaattttc aaagttccta gcaaaccttc gtcataaatc atacccgata atttcattaa
    83341 tgtcatttca ccagtcaata ctttcacatc acaataacct gattctatca tcacctgttc
    83401 ccaaccatct tgagttaaag gacctacatt tacatgaatt gcttgtgata attcctgtct
    83461 gatagactct ttagcttcct taagaagcac atcatgcgtc aatagaagac ctccaggttt
    83521 taataccctt agatattcca ttacacattt tttcttagct tgatcggctt gcatagtcag
    83581 catagcttca tttataacaa tatcaaaact agcatcttga taaggaagtt tcattgcatt
    83641 tgctctttca aaactgatta aatgagcaac acctgccgtt ccagcagatt ttttagccac
    83701 ttctaaagct tgagcatcca tatcaacagc agttatcttg caaccaaaac gctgtgccaa
    83761 ctcaattgct gtagttcccc tattacacgc aacctctagt attctctttt cttttgaaaa
    83821 tcctccttct gcaattaacc aatctgtggc acgctttcca cctggacgta agcgtttttt
    83881 ccccaatttt gctaaaaact tatgacctgc ttctgacatt tgaacacctc tgttttttct
    83941 tcattataac acaaaatgat attatctgac aattctaatc tattatttga taaactagaa
    84001 tcaaaagcat acaagtcacc ataactatag cataaattta ttattacctc tctagttcga
    84061 attcaattgc tcacgtagtt tacgcatata gcttcacttg tagatggtac ccacaaataa
    84121 tactcaatgg aaatcaaaga gcaaactagg aaactagccg taagctgctc aaagtacagc
    84181 tttgaggttg cagataaaac tgacgaaatc agtaatcata cgtacggcaa ggcgacgttg
    84241 acgtggtttg aagagatttt cgaagagtat taaagagcat cacaatatag atgcataata
    84301 tgacttccct agcaaaaagg agagaagcat tttgtttctc tccctagatt aactgatatc
    84361 tctccactac aattgataaa gagatatctt ttcttgtagt gttttgaatt ttatttattt
    84421 tagtaaattg ttttttcagt ttctacatcg aagaagtgtg ctttgttcaa gtcaaatcca
    84481 agctcaactg ttgcacctgt ttgcaagtag tcacgagcat caacttttgc aacaaactcg
    84541 tctttaccaa cttggcagta aaggtgagat tctgaaccaa gcagttctga tacagagata
    84601 gtcgctttta caacacagtc tgggaatgtt tcaaggaaag caggttctgc attcacgtct
    84661 tctggacgga taccaaagat caattctttt ccttcgtagc ctttttcacg aagaactttc
    84721 aatgctcctt ctggcacttt caaacggaaa ccgtcagaaa caatttcgct accaaccaat
    84781 ttcacgttga tgaaattcat agctgggctt ccgatgaatc ctgcaacaaa tttgttaact
    84841 ggatttttgt aaacttcttg aggagtaccg atttgttcta cacgtccgat agtacctgta
    84901 ccagcagggt tcttagtagc tgacataata acgatacggt ctgcaagtgt catcgcttct
    84961 gtttggtcgt gagttacata gatagttgta gctccgatac gacggtgaat tttagcgatt
    85021 tcagcacgca ttgatacacg aagtttggca tccaagtttg acaaaggttc gtccatcaag
    85081 aatactttcg catcacggac aatcgcacgc cccatggcaa cacgttgacg ttgaccacct
    85141 gaaaggtcag ctggtttacg ttccaagaat tctttcaatc caagtatttc agctgcttct
    85201 tgaacacgtt tgttaatgtc ttctttgctg tatttacgca atttcaaacc gaaagccatg
    85261 ttgtcataaa cagtcatgtg tgggtaaaga gcgtagtttt ggaataccat ggcgatatca
    85321 cggtcttttg gagctacgtc gttgacaacc acgccatcga tagatgcagt accttctgtg
    85381 atgtcttcaa gaccagcaat catacggagt gtagttgatt taccacatcc tgaaggtcct
    85441 acgaaaacga taaattcttt atctttgatg ttcaagttga aatcttcaac tgaatagtgt
    85501 tcgctgtttg gatatttttt gtaaatattt ttaagattca attctaccat gaggtgaact
    85561 ccttttgtct tttgataatt atattataga tgaaaacgct ttatatttct atggcaagat
    85621 gaccaaaaaa ataaaaaagt tctgtgcaac ttgcacaaaa ctttagagaa tatcggagaa
    85681 tttgaagaag ataatcttta ttattcttct atgacaaaag cagaaacaag gatcagtttt
    85741 cccatatttt cgctgattct ccactacatt tgactggatt ctaatttttt agagaaatac
    85801 aaaagagcta gctttagcta actcttttcc tatgcggaga gagggacttg aaccctcacg
    85861 acctaaagcg gtcacaggat ccttagtcct gcgcgtctgc caattccgcc atccccgcat
    85921 cgattacttt actagtatat caacttttgg gatgcttgtc aacacttttt ttcaaatttt
    85981 ttcattttca ccaaccaggt tactcagaaa gttcatttag attttcatct actaacttag
    86041 ctccgagtgt atttttgaaa tgacctaggg caaattgatg attttcaggc cagatggaag
    86101 caacagctgg tttaacaatc tcgatgtcat atcctagatt ataggcatct atagctgtat
    86161 gtaggacaca gatatccgtc aagacacctg ttaagataac ggtagacact ctacgctctc
    86221 tcaaacgaat atctaggtca gtccctgaaa aagctgagta atggcgttta tccatccaaa
    86281 agacacgact gtctgaacca tgctcttgat aaaagatccc caaatctcca tataaattcc
    86341 gtccactcgt cccaatcaga ttatgaggag gaaataactt actttccgga tggaaacaat
    86401 cgttttcttc atgagcatca atagtaaaga agatataatc tcctcgttca aaagctaatc
    86461 gagttacctt gctgatggca tccgaaatcg cctgagctgg agcacctgct gtcagcttcc
    86521 cactatcagc aacaaaatct tctgtataat caatcgaaat taaagccttt gtcattagta
    86581 atctcttttc ttcacttctt caaaaatatc tgaaatcaag accttaagat aggttccctt
    86641 cattccaagt gagcgacttt caataatccc cgcagactca agtttacgaa gagcattgac
    86701 aatcacagag cgagtgattc cgatacgatc tgcaatcact gacgcagtca acttcccttc
    86761 atttccattt aattccccta aaattgctga aacagcacgg agttcggagt aagaaagggt
    86821 attgaccgcc atggtgacag cagtacgacg acgaatattt ttctcatctt cttcacgttg
    86881 gaagttaaga agctgaatcc caacaacggt actggcaatc tcaacaagaa ccaagtcctc
    86941 atcttcgaat tttttatcat tacgccaaat aatcaaagaa ccaaggcgaa tccccgatac
    87001 atgaatcggt gcaatagtcg tcaagccatc tggaaaatca tctctactct caacagggaa
    87061 aatactcata tcatgctcaa caggcaagtt tgcttctgtt tcgtaaatca tattagcccc
    87121 ttgaacgtag tcatctggga aaatcttagt ttggaagaat tgctctacgc gatctgtatt
    87181 tgttttataa cgcataaaat agccaagcag acgtccctta ctattgataa tgcaggcatt
    87241 gcaatgaata atatccgcta actgacgcgt aatagcgttg taagggagct catcctgcaa
    87301 ctgctcctct gagcgtttca aaattgatgt aatttttcta gttttttcta ataaatgtgc
    87361 catttttcac ctcgaattta atcgctatca ttataacata aaaacgtctc tttttcaata
    87421 attatctgaa aattccttat tgacttgcat tgacttacaa tttaattaaa aaccagaata
    87481 tttttaatta aattgttcct tttctattga caagtcgcct atttttgtgt attataatat
    87541 tataaaagat aatatagtaa ttttatttgt cttttcacat tcggtctcct tatataaaaa
    87601 agcgattcat tttgaaccgc tttttcttat ttatcacctt tgttacgaat aacaaagcct
    87661 gtttgctttt cgcttaaagt attgcgtggt tttttattat ccttacggta acgtttttcc
    87721 ttatcaaaac gatcgttgcc acgacttcct tttttgaact catcacggcg accattgcca
    87781 cggcgatcac gctctcgacg gtcgtcccca cgacggcctc cacgacctcc cttagcttta
    87841 ccaccgaaac cattacctga tggtttaaac ggtagtggtt tttcacgtgc aatctccact
    87901 tctggaaggc tatctgggtc ttggactgtc agactcaaga tatacattgc caattcttct
    87961 ggagtaaact cagcagccaa tttgcgagca tccttaccaa atttctcaaa gttggcacga
    88021 atggtttcat ctgcaaaatc acgttcgatt ttcttgagag ccacctgttt ttttgattgg
    88081 aaggattctt ctacacttgc aggtttgaga cctttcatgc gtttcttagt caagttttca
    88141 atgatttgaa ggtaacccat ttcgtttgga gcaacaaaag taatagattg acctgactta
    88201 ccagcacgac ctgtacgacc gatacggtga acataactct caggatcttg tggaatatcg
    88261 tagttgtaga catgggtcac acctgaaata tccaaaccac gcgctgcaac gtctgtcgca
    88321 accaaaacat caagattgcc atttttaaag tcacgaagga cacgaagacg tttgttttgg
    88381 tctaggtcgc catgaattcc ttctgcacgg aagccacgaa ttttcaaacc acgagtcaat
    88441 tcatccacac ggcgtttggt acgaccaaat acaatagcga gttctggttg tgccacatcc
    88501 atgagacgag tcatggtgtc aaatttttct tgttccttaa cacggatata gtactggtca
    88561 accaattctg ttgtcaattc cttagccgca atcttgacat gttcaggggc tttcataaac
    88621 tgaacaccga tacgtttgat ggcatctggc atagttgctg agaaaagcaa agtttgacgg
    88681 ttctcaggta cacgggaaat aatggcttcg atgtcttcaa ggaagcccat gttaagcatt
    88741 tcatccgctt cgtcaaggat aagggtttca atgttttgta atttcaaggc cttgcgttta
    88801 atcaagtcca agaggcgacc tggagttccc accacgatat gggcaccaga tttaagagcc
    88861 ttaatttgtt tttcaatgct tgatccgcca tatactgaac ggactttgac tcccttacta
    88921 cgaccaaagc ggaagagttc ttcttgactt tggacagcta gttcacgagt tggagcgatg
    88981 accaaggctt ggatagtcgc ttcttctgta cggatttttt caagggtagg caagccaaag
    89041 gctgcagttt ttcctgtacc agtctgagct tgaccgataa catccttgcc ttcaagggcc
    89101 aaaggaatag tttgttcttg gataggacta gcttctacaa aaccagcttt ttcaatttct
    89161 gccagcaaat cagcagacaa gtttaattca ttaaatttca cgttattctt ctttctaaag
    89221 gtggtgcgaa gccaccctat agggcttagt ttatactttt ctttttatga cgtattttca
    89281 tataactaga tataaaatcg tgttgcttct tttccacaaa agaaaagtac tgttttcttt
    89341 gcaacctatc tagtataaca caagaccaga gcaaaagata gccccatttc tacagaaaat
    89401 catgtaagcg gtttttgact ttcttttttg attgaacgac ctagataata agacaaagcc
    89461 aaggcgatac tgtataaaat gagaaaaacg aacaaggttt gtgtgtacga atgagccatt
    89521 ttataagtct ctgctaataa aataggtccc gctaaaccag ccattgccca agctgttaaa
    89581 atatatccat gcagagcggc caattccttg gttccaaaaa tatcactgag ataagctggg
    89641 atcaatgaaa aaccagctcc atagcaagtc atcaaaatag acatagcgac tacaaataaa
    89701 acggaatctg taaagagcca aagtgagaga gaaaataaaa gattaacaag cagtaatata
    89761 ctaaaggtta gagggcgacc gatatagtca gataagctcg cccagagcaa gcgaccaaat
    89821 ccattgaaaa tccctaaaac gcccaccatt actgctgcat gacttgtaga caagccagcc
    89881 atctcctgtg ccattggcga tgccgctgaa attaagccta aaccacaagc tatgttgata
    89941 aagaaaataa tccaaagtat ataaaaccga ttgcttttta gagcctgatt tgcagtcatc
    90001 ccttgcgtca gagagtctgt tttttctttc cctgaagcag ataaaattgc aagctcttgc
    90061 tcatttggac gcttaatgaa ttgtgaagct aggagcatga taataaagta acttgcacct
    90121 aaaatataaa aagtttctac aagccctacc cctgcgatga gatgttgcgc tatgggacta
    90181 gtcaataaag aagcaaaacc aaaccccata atcgctaaac ctgttgcgag accacgttta
    90241 tcaggaaacc attttataat cgttgacaca ggggtaatat agcctgctcc caaaccaagc
    90301 ccacctaaaa tgccataagc tagatacaac aaccacagtt cctgacggtc tattgcaaat
    90361 cctgttaaga tatttccacc tgcgtataga aaagcagata gactccccat gactctcgga
    90421 ccaaattttt ctaccaaacg ccccataaat gcagccgata agcccaaaca aaagattgct
    90481 agactaaagg caaaggcaac agaagcctga tcccatcccg ttttttcaat aatagggtta
    90541 cgataaacac tccaagcata agtcgaaccc agcattaagt gtaaaatgac cccagcaaag
    90601 gcaataatat aacgattcga tttcataaaa cctcctattt tcgaacattt attctatctt
    90661 atataaaaat agataggatt ttagtttatc aagcttgtca aaaaattact agttttttgt
    90721 ctggaaagcg tttttatctt tttctgtctt ttccgtagca gaattgtgca aaagtttttt
    90781 tcttgtgcta gaatgaaatt cgaataggag gaagataaat gttaacatac gatttaattg
    90841 ttattggatt tggtaaagct ggtaaaacac tagcaggtaa attggcttca gctggcaaaa
    90901 aagttgccct cgttgaacgc agcaaggcta tgtacggtgg aacttgtatc aacattggtt
    90961 gtatcccaac taaaaccttg ctagttgctg ctgaaaagga cttgtctttt gaagaagtga
    91021 ttgctactaa aaacacgatc actggtcgcc tcaacggtaa aaactatgcg actgttgctg
    91081 gtacaggcgt agatatcttt gatgcggaag ctcacttcct ttcaaataaa gtcatcgaaa
    91141 tccaagctgg taatgaaaag aaagaactga ctgctgaaac tatcgtcatc aacactggtg
    91201 ctgtttcaaa cgtcttgcca atccctggac ttgctacaag caaaaacgtc tttgactcaa
    91261 caggtatcca aagcttggat aaattgcctg aaaaacttgg agtccttggt ggcggaaata
    91321 tcggtcttga atttactggc ctttacaata aactaggaag caaggttaca gtcctagatg
    91381 ccttggatac attcctacct cgtgcagaac cttccatcgc agctcttgct aaacaataca
    91441 tggaagaaga cggtattgaa ttgcttcaaa atatccatac tactgaaatt aaaaacgacg
    91501 gtgaccaagt gcttgtcgta actgaagacg aaacttaccg tttcgacgcc cttctctacg
    91561 caactggacg caaaccaaat gtagaaccac ttcaacttga aaatacagat attgaactaa
    91621 ctgaacgtgg cgctattaaa gtagataaac actgtcaaac aaacgttcct ggtgtctttg
    91681 cagttggaga tgtcaacggt ggtcttcaat ttacttacat ttcacttgat gacttccgtg
    91741 ttgtttacag ctaccttgct ggagatggca gctacacact tgaggaccgt ctcaatgtgc
    91801 caaatactat gttcatcaca cctgcacttt cacaagttgg tttgactgaa agccaagcag
    91861 ctgatttgaa acttccatac gcagtgaaag aaatccctgt tgcagccatg cctcgtggtc
    91921 acgtaaatgg agaccttcgc ggagctttca aagctgttgt taatactgaa acaaaagaaa
    91981 ttcttggtgc aagcatcttc tcagaaggtt ctcaagaaat catcaacatc attactgttg
    92041 ctatggacaa caagattcct tacacttact tcacaaaaca aatcttcact cacccaacct
    92101 tggctgagaa cttgaatgac ttgtttgcga tttaagttga aatctcatct taactgacag
    92161 ccctctttgg gctgttttta cttctacgaa acaccaaatc tgtcttttcc ctcttttgtg
    92221 atataataga aacatgaact taaaaactac tttgggcctt cttgctgggc gttcttccca
    92281 cttcgtttta agccgtcttg gacgtggaag tacgctccca ggtaaagtcg cccttcaatt
    92341 tgataaagat attttacaaa acctagctaa gaactacgag attgtcgttg tcactggaac
    92401 aaatggaaaa accctgacaa ctgccctcac tgtcggcatt ttaaaagagg tttatggtca
    92461 agttctaacc aacccaagcg gtgccaacat gattacaggg attgcaacaa ccttcctaac
    92521 agccaaatct tcaaaaactg ggaaaaatat tgccgtcctc gaaattgacg aagccagtct
    92581 atctcgtatc tgtgactata tccagcctag tctttttgtc attactaata tcttccgtga
    92641 ccagatggac cgtttcggtg aaatctatac tacctataac atgatattgg atgccattcg
    92701 aaaagttcca actgctactg ttctccttaa cggagacagt ccacttttct acaagccaac
    92761 tattccaaac cctatagagt attttggttt tgacttggaa aaaggaccag cccaactggc
    92821 tcactacaat accgaaggga ttctctgtcc tgactgccaa ggcatcctca aatatgagca
    92881 taatacctat gcaaacttgg gtgcctatat ctgtgaaggt tgtggatgta aacgtcctga
    92941 tctcgactat cgtttgacaa aactggttga gttgaccaac aatcgctctc gctttgtcat
    93001 agacggccaa gaatacggta tccaaatcgg cgggctctat aatatctata acgccctagc
    93061 tgctgtggcc atcgcccgtt tcctaggtgc cgattcgcaa ctcatcaaac agggatttga
    93121 caagagccgt gctgtctttg gacgccaaga aacctttcat atcggtgaca agaaatgtac
    93181 ccttgtcttg attaaaaatc cagtcggtgc aacccaagct atcgaaatga tcaaactagc
    93241 accttatcca tttagcctat ctgtcctcct taatgccaac tatgcagatg gaattgacac
    93301 tagctggatc tgggatgcag actttgagca aatcactgac atggacattc ctgaaatcaa
    93361 cgctggcggt gttcgtcatt ctgaaatcgc tcgtcgcctc cgagtgactg gctatccagc
    93421 tgagaaaatc actgaaacga gtaatctgga gcaagttctc aagaccattg agaatcaaga
    93481 ctgcaagcat gcctatattc tggcaactta tactgccatg ctggaatttc gtgaactgct
    93541 ggctagtcgt cagattgtta gaaaggagat gaactaatgg tttatacttc actttcctca
    93601 aaagatggca attaccccta tcagctcaac attgcccacc tctacggaaa tctcatgaat
    93661 acctacgggg acaatggaaa catcctcatg ctcaaatatg tggctgaaaa actgggagcc
    93721 catgtgaccg ttgacatcgt ttctctccat gatgactttg atgaaaatca ctacgacatc
    93781 gcctttttcg gtggtggtca agactttgaa caaagtatca ttgcagacga cctacctgct
    93841 aaaaaagaga gcattgacaa ctacatccaa aacgacggtg tagttctggc tatctgcggt
    93901 ggtttccaac tattgggtca atattatgtt gaagcttcag gaaaacgtat cgaagggcta
    93961 ggggtcatgg gacactacac gctcaaccag accaataacc gttttatcgg tgacatcaag
    94021 attcacaatg aagatttcga tgaaacctac tatggatttg aaaatcacca aggccgtacc
    94081 ttcctctctg atgaccaaaa accgctggga caggttgtct atggaaatgg aaacaacgaa
    94141 gaaaaggtcg gtgaaggggt tcattataag aatgtctttg gttcctactt ccacgggcct
    94201 atcctctctc gtaatgccaa tctggcttat cgcctagtta ctactgccct caagaagaaa
    94261 tatggtcagg atatccaact ccctgcctat gaggatatcc tcagccaaga aatcgctgaa
    94321 gagtacagtg acgtcaaaag caaggctgac ttttcttaaa caaaggaaaa tgatatcaaa
    94381 gaactccgtt atcttgtcgg agttttttgt cttttctttt acccttctcc cttgcatttt
    94441 ctctcatttt ttgccaaaat agaggggtag aaagaaggta gcatatgtct aaattacaac
    94501 aaatcctaac atatcttgaa tcagaaaaac tagacgtcgc tgtcgtatct gaccccgtca
    94561 caatcaatta cctcactggt ttttacagtg atccccatga acgccaaatg ttcctctttg
    94621 tcctagcgga tcaggaacct ctcctctttg tcccagctct tgaagtagaa cgtgcaagta
    94681 gcaccgtttc cttcccagta gtgggctatg tcgattctga aaatccatgg caaaaaatca
    94741 aacatgctct tccacaactt gacttcaaac gtgtcgctgt tgagtttgac aatctcatct
    94801 tgaccaaata ccatggtttg aaaacagttt ttgagactgc tgagtttgac aacctcactc
    94861 ctcgtatcca acgcatgcgc ctcatcaaat cagctgatga agtgcaaaaa atgatggttg
    94921 caggtcttta tgctgacaag gctgttcatg ttggttttga caatatttct cttgataaga
    94981 ctgagacaga tatcatcgca caaatcgact ttgccatgaa acgtgaaggt tatgaaatga
    95041 gctttgatac catggtcttg actggtgata atgctgcgaa tccacacggc attccagcag
    95101 ctaataaggt tgaaaatgat gctcttctcc tctttgacct gggtgttctg gtcaatggct
    95161 atgcgtcaga tatgactcgt acagtcgctg tcggcaaacc agaccaattc aagaaagata
    95221 tttacaactt gactcttgaa gcccaacaag ctgctcttga ctttatcaag ccaggtgtga
    95281 ctgctcatga agtggaccgc gctgcccgtg aggtcatcga aaaagctggt tatggtgagt
    95341 acttcaatca ccgtctcggg catggtatcg gtatggatgt ccatgaattc ccatctatca
    95401 tggaaggaaa cgacatggtc atcgaagaag gcatgtgctt ctctgttgaa ccaggtatct
    95461 atatccctgg taaagtcggt gttcgtattg aagactgcgg tgttgttacc aaggatggct
    95521 tcgacctctt tacaagcacc agcaaagatt tgctttattt tgattaaact atatagcccc
    95581 tatgctttcc tttcaaaata tctaggggct attttattgt catttttctg ctattatgct
    95641 aaagaaattg gctgcaataa tctaacccta agtgtctgga atgataacga gggtgctctc
    95701 cgcttttatc aaagacaagg gatgaaaccc caagaaacaa caatggaaat gataattgat
    95761 taagaagtca tctatcaaaa gatgttagaa aaagttcaat ttcactagaa aatgaggaaa
    95821 atcttcccac aataaaacgc atagtatcaa ggtttttctg tactgccccc caaaagttag
    95881 acaaataatt tatccaaagg atttagttct gtattgcaca gggctaagtc cttttagttt
    95941 taccttaatt cgtttattgt tgtaataatc aatatagtct ataatggctt gttccaattg
    96001 attaagtgat ttaaatgttt tctcatagcc ataaaacatt tcggatttta aaatgccaaa
    96061 gaaggactcc atcataccgt tgtcttggct gtttcccttg cgtgacatag atgcttgaat
    96121 tcccttactc tcta
//
LOCUS       DAVHSH010000004        71878 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000004 DAVHSH010000000
VERSION     DAVHSH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.004"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            142..390
                     /locus_tag="VVR08_000345"
                     /pseudo
     CDS             142..390
                     /locus_tag="VVR08_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            521..1693
                     /locus_tag="VVR08_000346"
     CDS             521..1693
                     /locus_tag="VVR08_000346"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU6074317.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1693..2967
                     /locus_tag="VVR08_000347"
     CDS             1693..2967
                     /locus_tag="VVR08_000347"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU6074318.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNDQEYTVPYVTEEPSVVAAASYASKIIKRTGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3002..3967)
                     /locus_tag="VVR08_000348"
     CDS             complement(3002..3967)
                     /locus_tag="VVR08_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6074319.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3948..5402)
                     /locus_tag="VVR08_000349"
     CDS             complement(3948..5402)
                     /locus_tag="VVR08_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6074320.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGRKTN"
     gene            5779..7662
                     /locus_tag="VVR08_000350"
     CDS             5779..7662
                     /locus_tag="VVR08_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6074321.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            7811..8698
                     /locus_tag="VVR08_000351"
     CDS             7811..8698
                     /locus_tag="VVR08_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6074322.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8741..9358)
                     /locus_tag="VVR08_000352"
     CDS             complement(8741..9358)
                     /locus_tag="VVR08_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU6074323.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9773..9961)
                     /locus_tag="VVR08_000353"
                     /pseudo
     CDS             complement(9773..9961)
                     /locus_tag="VVR08_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10354..10545)
                     /locus_tag="VVR08_000354"
     CDS             complement(10354..10545)
                     /locus_tag="VVR08_000354"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074324.1"
                     /translation="MKIKEQTRKPAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYTYGKAKLTWFEEIFEEY"
     gene            10668..11561
                     /locus_tag="VVR08_000355"
     CDS             10668..11561
                     /locus_tag="VVR08_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074325.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11558..12757
                     /locus_tag="VVR08_000356"
     CDS             11558..12757
                     /locus_tag="VVR08_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074326.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTENIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13110..13877)
                     /locus_tag="VVR08_000357"
     CDS             complement(13110..13877)
                     /locus_tag="VVR08_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074327.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNISSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(13894..14589)
                     /locus_tag="VVR08_000358"
     CDS             complement(13894..14589)
                     /locus_tag="VVR08_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074328.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14594..14959)
                     /locus_tag="VVR08_000359"
     CDS             complement(14594..14959)
                     /locus_tag="VVR08_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6074329.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            15099..15572
                     /gene="nrdR"
                     /locus_tag="VVR08_000360"
     CDS             15099..15572
                     /gene="nrdR"
                     /locus_tag="VVR08_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU6074330.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15573..16742
                     /locus_tag="VVR08_000361"
     CDS             15573..16742
                     /locus_tag="VVR08_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU6074331.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            16743..17639
                     /gene="dnaI"
                     /locus_tag="VVR08_000362"
     CDS             16743..17639
                     /gene="dnaI"
                     /locus_tag="VVR08_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU6074332.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17636..18349
                     /locus_tag="VVR08_000363"
     CDS             17636..18349
                     /locus_tag="VVR08_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU6074333.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18363..19673
                     /gene="der"
                     /locus_tag="VVR08_000364"
     CDS             18363..19673
                     /gene="der"
                     /locus_tag="VVR08_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU6074334.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            19761..20096
                     /locus_tag="VVR08_000365"
     CDS             19761..20096
                     /locus_tag="VVR08_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074335.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20236..20571
                     /locus_tag="VVR08_000366"
     CDS             20236..20571
                     /locus_tag="VVR08_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074336.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASGWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            20756..21547
                     /locus_tag="VVR08_000367"
     CDS             20756..21547
                     /locus_tag="VVR08_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074337.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            21540..22181
                     /locus_tag="VVR08_000368"
     CDS             21540..22181
                     /locus_tag="VVR08_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074338.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            22185..22835
                     /locus_tag="VVR08_000369"
     CDS             22185..22835
                     /locus_tag="VVR08_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6074339.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            22846..23133
                     /locus_tag="VVR08_000370"
     CDS             22846..23133
                     /locus_tag="VVR08_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074340.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICWLSLWINLFITFAILPIFGN"
     gene            23279..25792
                     /gene="secA"
                     /locus_tag="VVR08_000371"
     CDS             23279..25792
                     /gene="secA"
                     /locus_tag="VVR08_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU6074341.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            25873..26904
                     /locus_tag="VVR08_000372"
     CDS             25873..26904
                     /locus_tag="VVR08_000372"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6074342.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            26906..27937
                     /locus_tag="VVR08_000373"
     CDS             26906..27937
                     /locus_tag="VVR08_000373"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6074343.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            27976..28344
                     /locus_tag="VVR08_000374"
     CDS             27976..28344
                     /locus_tag="VVR08_000374"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU6074344.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28334..29437
                     /locus_tag="VVR08_000375"
     CDS             28334..29437
                     /locus_tag="VVR08_000375"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU6074345.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29456..31471
                     /gene="recG"
                     /locus_tag="VVR08_000376"
     CDS             29456..31471
                     /gene="recG"
                     /locus_tag="VVR08_000376"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU6074346.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLKLEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            31787..32767
                     /locus_tag="VVR08_000377"
     CDS             31787..32767
                     /locus_tag="VVR08_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU6074347.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHISQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLVF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33617..33844
                     /locus_tag="VVR08_000378"
     CDS             33617..33844
                     /locus_tag="VVR08_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074348.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34132..37029
                     /gene="nanA"
                     /locus_tag="VVR08_000379"
     CDS             34132..37029
                     /gene="nanA"
                     /locus_tag="VVR08_000379"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU6074349.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNDQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKIYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38045..38497
                     /locus_tag="VVR08_000380"
     CDS             38045..38497
                     /locus_tag="VVR08_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6074350.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38516..39853
                     /locus_tag="VVR08_000381"
     CDS             38516..39853
                     /locus_tag="VVR08_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6074351.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            39932..40816
                     /locus_tag="VVR08_000382"
     CDS             39932..40816
                     /locus_tag="VVR08_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6074352.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            40816..41649
                     /locus_tag="VVR08_000383"
     CDS             40816..41649
                     /locus_tag="VVR08_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6074353.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            41667..43760
                     /gene="nanB"
                     /locus_tag="VVR08_000384"
     CDS             41667..43760
                     /gene="nanB"
                     /locus_tag="VVR08_000384"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU6074354.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            43772..44875
                     /locus_tag="VVR08_000385"
     CDS             43772..44875
                     /locus_tag="VVR08_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6074355.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45049..45747
                     /locus_tag="VVR08_000386"
     CDS             45049..45747
                     /locus_tag="VVR08_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6074356.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            45766..47282
                     /locus_tag="VVR08_000387"
                     /pseudo
     CDS             45766..47282
                     /locus_tag="VVR08_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            47407..48735
                     /locus_tag="VVR08_000388"
     CDS             47407..48735
                     /locus_tag="VVR08_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6074357.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            48987..49853
                     /locus_tag="VVR08_000389"
     CDS             48987..49853
                     /locus_tag="VVR08_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6074358.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            49869..50708
                     /locus_tag="VVR08_000390"
     CDS             49869..50708
                     /locus_tag="VVR08_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6074359.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            50981..51433
                     /locus_tag="VVR08_000391"
     CDS             50981..51433
                     /locus_tag="VVR08_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6074360.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            51530..51874
                     /locus_tag="VVR08_000392"
     CDS             51530..51874
                     /locus_tag="VVR08_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074361.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            52161..52805
                     /locus_tag="VVR08_000393"
     CDS             52161..52805
                     /locus_tag="VVR08_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6074362.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            52974..53891
                     /locus_tag="VVR08_000394"
     CDS             52974..53891
                     /locus_tag="VVR08_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU6074363.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSSERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            53909..54793
                     /locus_tag="VVR08_000395"
     CDS             53909..54793
                     /locus_tag="VVR08_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6074364.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(54809..55660)
                     /locus_tag="VVR08_000396"
     CDS             complement(54809..55660)
                     /locus_tag="VVR08_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6074365.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            55860..57917
                     /gene="pbp2b"
                     /locus_tag="VVR08_000397"
     CDS             55860..57917
                     /gene="pbp2b"
                     /locus_tag="VVR08_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU6074366.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELGNGGAKYSEGVYAVALNPKTGAVLSMSGLKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     AYMVQTALGLMGQTYQPNMFVGTSNLESAMGKLRSTFGEYGLGSATGIDLPDESTGFV
                     PKDYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGAAVSISGKTGTA
                     ESYVEGGQEANNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYNQHH
                     PMN"
     gene            57928..58524
                     /gene="recR"
                     /locus_tag="VVR08_000398"
     CDS             57928..58524
                     /gene="recR"
                     /locus_tag="VVR08_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU6074367.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            58700..59743
                     /locus_tag="VVR08_000399"
     CDS             58700..59743
                     /locus_tag="VVR08_000399"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU6074368.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            59827..61200
                     /locus_tag="VVR08_000400"
     CDS             59827..61200
                     /locus_tag="VVR08_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU6074369.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGNQSVQLHNQMTLSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            61187..61798
                     /locus_tag="VVR08_000401"
     CDS             61187..61798
                     /locus_tag="VVR08_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6074370.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEGSWALPGGFGEV
                     GYSPTENILKEIEEETGFKVKVERLLAVFDINRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPVLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            61889..62593
                     /locus_tag="VVR08_000402"
     CDS             61889..62593
                     /locus_tag="VVR08_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU6074371.1"
                     /translation="MNLWDIFFTTQATKPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIVKEA"
     gene            62812..64185
                     /gene="ftsA"
                     /locus_tag="VVR08_000403"
     CDS             62812..64185
                     /gene="ftsA"
                     /locus_tag="VVR08_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU6074372.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64202..65461
                     /gene="ftsZ"
                     /locus_tag="VVR08_000404"
     CDS             64202..65461
                     /gene="ftsZ"
                     /locus_tag="VVR08_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU6074373.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65466..66137
                     /locus_tag="VVR08_000405"
     CDS             65466..66137
                     /locus_tag="VVR08_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU6074374.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66147..66686
                     /locus_tag="VVR08_000406"
     CDS             66147..66686
                     /locus_tag="VVR08_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU6074375.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            66686..66949
                     /locus_tag="VVR08_000407"
     CDS             66686..66949
                     /locus_tag="VVR08_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU6074376.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            66946..67731
                     /locus_tag="VVR08_000408"
     CDS             66946..67731
                     /locus_tag="VVR08_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU6074377.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            67740..68528
                     /gene="divIVA"
                     /locus_tag="VVR08_000409"
     CDS             67740..68528
                     /gene="divIVA"
                     /locus_tag="VVR08_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU6074378.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            68876..71668
                     /locus_tag="VVR08_000410"
     CDS             68876..71668
                     /locus_tag="VVR08_000410"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU6074379.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPVGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRTWGVPLPIFYAEDGTAIMVAETIEHVAQLFEKHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
BASE COUNT        21793 a        13050 c        15833 g        21202 t
ORIGIN      
        1 gaaatcatcg taaacgcttc ggattacgaa tgaatttgag tgctggtatt atcaatcatg
       61 aactaggatt ctagttttgc aggaagtcta ctactttact tattgtctgt aaatctactg
      121 accttgttgt ttatcccagt catggtttct agttcgggct cagagtttca aagtggatgg
      181 taagagcatc aattgattgc tgagaaggtt agtaaaacac ttgacaagac atttgataag
      241 gatgtcagag aaattccgac cagtcagttt tatcaaaaat ttgtagatga gatgggaagg
      301 acttactcag gaaatttgat cctccaggag ctgataactg tgaatggagc ttataaagct
      361 acttatatcg gtgaactctc tagcaactaa tcattcttta aaatgatgac caataagagg
      421 cttgatttgg tgaatcaagt cttttttctc tcttttactg ccatttgtga taaaatagta
      481 tagaacgatt ttttacatga atgataaaac agaggtaaat atgacaatcg gtattgataa
      541 gattggtttt gcgaccagtc aatatgtctt gaaattacaa gacttagcag aagcgagggg
      601 aattgaccct gaaaaattaa gtaaaggact cttactcaag gaattgagta ttgcgcccct
      661 aactgaggat atcgtgacct tggcggccag tgctagtgac tctattttaa ctgagcaaga
      721 aagacaagaa gttgacatgg tcattgtggc gaccgagtca ggaattgacc agagtaaggc
      781 tgcggccgtc tttgtgcatg gcttgctggg catccagccc tttgctcgta gtttcgagat
      841 taaagaagcc tgctatgggg cgacagctgc cctccattat gccaaattgc atgtggaaaa
      901 ttctccggag tccaaggtat tggtcattgc cagtgatatt gccaaatatg gtattgaaac
      961 tccgggagaa ccaactcaag gtgctggaag tgtagctatg ttgattacac aaaatccacg
     1021 catgatggcc tttaataatg acaatgtagc tcagacccgt gacatcatgg atttctggcg
     1081 accaaattac tcgacaactc cttatgtaaa tggtgtctat tctacccaac aatacttgga
     1141 tagtttgaaa acgacttggc ttgaatatca aaaacgctac cagcttactt tggatgattt
     1201 tgctgctgtt tgtttccact tgccttatcc taaattagcg ctaaaaggct tgaaaaaaat
     1261 catggataag agcctgcctc aagagaaaaa agacctctta caaaagcatt ttgaccagtc
     1321 tattctctac agtcaaaagg tggggaacat ctacacaggt tcacttttcc ttggactttt
     1381 gtctctcttg gaaaatacag atagcttgaa agctggggat aaaatcgccc tttatagtta
     1441 cggaagtgga gctgtggctg agttcttcag tggtgaattg gttgaaggat atgaagctta
     1501 tttggataaa gaccgtttga acaagctcaa ccaacgaact gccctatccg ttgcagacta
     1561 tgaaaaggtc ttttttgagg aagtaaactt ggatgaaaca aactctgccc agtttgctgg
     1621 ctatgaaaat caagattttg ccttggttga aattctcgac caccaacgcc gttatagcaa
     1681 ggttgaaaaa taatgaagat aagttggaat ggattttcta aaaaatcata ccaagagcgc
     1741 ctcgagctgt taaaagctca ggcgctcctt agtcctgaga gacaagctag tctggagaag
     1801 gatgaacaga tgagtgtgac tgtggcagac cagctgagtg agaatgtggt gggaactttt
     1861 tctctgcctt attcgctggt tccggaggta cttgtcaacg atcaggaata caccgttccc
     1921 tatgtgacag aagaaccctc tgtggttgcg gcggccagct atgccagcaa aatcatcaag
     1981 cgtacaggtg gttttactgc acaagtccat cagcgacaga tgattgggca ggtagccctt
     2041 tatcaagttg ctaatcctaa actagcgcaa gagaagattg ccagcaagaa agcggagctc
     2101 ttggagcttg ccaatcaagc ctatccttct atcgttaaac gtggaggtgg ggcgcgtgat
     2161 ctgcatgtcg agcagataaa aggcgaacca gactttctcg ttgtttatat tcatgtcgat
     2221 acccaggaag ccatgggtgc caatatgctc aacaccatgc tggaagcctt gaaaccagtc
     2281 ttagaagaac tcagtcaggg acagagtctc atgggaatcc tgtccaacta cgcgactgat
     2341 tctctggtga ctgcaagctg tcgcatggcc tttcgctact tgagccgcca aaaggatcaa
     2401 ggacgagaga ttgcggagaa aattgcgttg gctagtcagt ttgcgcaggc tgatccttac
     2461 cgagctgcta ctcataataa aggaattttt aatggtattg atgcgatttt gattgccact
     2521 ggtaatgact ggcgtgccat cgaagctggg gcccatgcct ttgccagtcg agatggacgc
     2581 tatcaaggtc ttagctgctg gacgctggac cttgaaagag aagaattggt cggtgagatg
     2641 accctgccca tgcctgtagc gactaagggt ggctctatcg gcctcaaccc acgtgtagct
     2701 ctcagtcatg atctactagg aaatccttct gccagagaat tagcccagat tatcgtgtcc
     2761 atcggtcttg ctcaaaattt tgcagccctc aaagccttgg taagtacggg catccagcaa
     2821 ggccacatga aactacaggc caaatctcta gctctcctag ctggggctag tgaatctgaa
     2881 gttgctcccc tagtagagcg cctcatctca gataaaacct ttaacctaga gacagcccag
     2941 cgctatctcg aaaatttaag atcataaaaa ctcagacgaa tcggtctgag ttttcttgtg
     3001 tttaaatact ttttcctggt aatagcgtaa ctggtaagaa gtaaccagtt gtggcgactt
     3061 ccttgccttc aatcttttgc aagagaagat caatagtgag acaagcaatc tcttccaaag
     3121 gttgcttgat agtagccaat tgagggtagt aattttcgat aaagtaggtc ccatcatagc
     3181 cgatgacctt gagctctttt gggacagaaa ttcccaattc ttgagcgatt ttaatgacca
     3241 gaatagctgt caaatcatcc gaagcaaaaa tggcatctgg tttttcccgg gtcaagatat
     3301 tcttgatttc catttctttt ctgacgggag aaaagtcact ggaaacattg ataataggag
     3361 cttttgggag tacggatgca aaaccagcgt ggcgcagtcc ggttggcgaa ttggaattgt
     3421 cattccctgt aatcatgatg atagactggg cacctgtctt gaccaaggtt tgggcagcaa
     3481 gaaccccacc agcatagttg tcagaggaga caacagggat gtctggcgat aggtttcggt
     3541 caaaggaaat aatcggcgct gtcacacgat tgtagtcttc gattcctagg ttgtgactac
     3601 cagaaatgat gccgtctacc tgattggctt ccaacatttc gatgtattcg cgttccttct
     3661 cagaatcatg ttcactgttg cagatgatgg tcttgtaacc atttttgaag agttggtgtt
     3721 ccaatttatc aatcaattct gcatagaaaa cattggaaat attggggaaa atcaagccga
     3781 ttaacttagc tgattttcct tgcagactac gagccaggtt gttgggttta tagcccaatt
     3841 ctctcatggc ttcattgact ttttggatgg ttttctcaga tagataccct tttttattga
     3901 taacccgaga aacggtagta ggactgacgc ctgcaagttt ggcgacatca gttagttttg
     3961 cgaccataat ctaattcata gtaaattcca gttgggtttc cagatttgat caggatacca
     4021 ttttggtccg catgtgggaa gacacgacca gaaaatactt tttctccttt attgatgaaa
     4081 atttcaaaga cagagttatc gatgaagatt gtagcagtag tagcctgatt ctcgataggg
     4141 caagaacgag ttgtcccaaa ttcttgggca tactgttctc cagcctggct acgatccact
     4201 gtcacttgac cgtttacaag gtcaaagttg attgaaagtc ccttaccttc tttatcagca
     4261 agtaagacaa tctcgctctg gctattagct tccaagttga gttcaagttc gtaagtgttc
     4321 ttggtttggg aacggtttga gaaggcttct tcagaagcac gaaggtcctt aatagcagcg
     4381 actggatact ggtagagctt gtcgtctttg atagtgagtt ccttgaccaa agagaaggtt
     4441 ccttggtggt caaaacggtc agatgggtaa gaaacatctg gcaaaccaag ccagctaact
     4501 gctagagcac gcccatcagg agcgttgaag gcttgagttg cataggcttc gaaaccgtaa
     4561 tccatgtttt gaagttgaga cacatctacc attttggcat ttttagggtc aaaggaagcc
     4621 ccaatcttat acatatttgg aaagatatta tcgtagtcta gaactttctt atccaatcct
     4681 tgtggacagt agagaaggac aggctgttcc tctacaaaga ccagattagg acattccatc
     4741 atgtaggcag tacggtcgtt agcaaagtca aggtcgccaa ctgcttgcca gtttgtgtag
     4801 tcgttattga cagccttgta gagacggacg aagccttttt tctccaagtc ctgtccaccg
     4861 acgacagcat agtattgacc tttaaagtta aaaatttgtg gatcgcggaa gtggtcagta
     4921 gagtctgctg gctggtcaat caagatcttg tcaatctttg taatcttacc ctccttgtcc
     4981 atcaaagcac cgatctggta tgggtgacgg atccagtttt catcgcgaac atttcctgta
     5041 taaaatagga ataagttatc gccaaattgc atggcagaac cagagtaggc accgtgacta
     5101 tctaatggag tatctggcaa aactttgact ccagtttctc taaagtgaac caaatcatca
     5161 ctttctagct gtgcccaaga ttttaaaccg tgggctgcac caaaaggaaa attctggtaa
     5221 aagaggatcc acttgccatc aaagtaagaa aagccatttg ggtcgttgag aagtcctgtt
     5281 tttggctcaa catggtaatg agtatgccat ggagattgtg ccatattttc ctttatatgt
     5341 tgaatttctt cttgcgtcca atcttgataa agtctgtaac gacgctcagt tgtccattcc
     5401 attcattcct ccaaaaatct tatcactttt aatagtaact gttttcgata aaaaatgcaa
     5461 gccctttatg ttaaaaaaga gaaaaaactg tcaaacgatt atcataaaat aaatacagga
     5521 aatcaatcaa atttttacga aaatgtgaaa gataatgaaa taaaagactt tttaaccaag
     5581 gttttaaact tatttttcaa gaaattcctg atgaaacagt caaaaacaat caatctaaag
     5641 cttgcccact aagtagatag aatatttttt ctgcaaaacg cttgacatat ttttaaaaca
     5701 tgataaaata atagtcgtaa gggcgaataa aatcgctttc aaacaagaac aaaatgttat
     5761 ataaggagat ttttgcaaat gaacaatcag gaaattgcaa aaaaagtcat cgatgccttg
     5821 ggcggacgtg aaaatgtcaa tagtgttgcc cactgtgcga cacgtctacg tgtcatggtc
     5881 aaagatgaag agaaaatcaa taaagaagtg attgagaact tggaaaaagt tcaaggtgct
     5941 ttctttaact cagggcaata ccaaattatc tttggtacag gtacagttaa caaaatgtac
     6001 gatgaagttg ttgtacttgg attaccaaca tcatctaagg atgacatgaa agcagaagtt
     6061 gctaaacaag ggaactggtt ccaacgtgct atccgtactt ttggtgatgt tttcgttcca
     6121 atcatcccag ttatcgtagc gacaggtctc ttcatgggtg tgcgtggtct tttcaacgct
     6181 cttgaaatgc cacttccagg tgactttgca acttacacac aaatcttgac agatacagcc
     6241 ttcatcatct tgccaggttt ggttgtgtgg tcaaccttcc gtgtatttgg tggaaatcct
     6301 gccgttggta tcgttcttgg tatgatgctt gtctctggct cacttccaaa cgcttgggca
     6361 gttgctcaag gtggtgaagt aacagcgatg aacttctttg gtttcatccc tgttgttggt
     6421 ttgcaaggtt ccgttcttcc agccttcatc atcggggttg tcggagctaa atttgaaaaa
     6481 gctgtccgca aggttgttcc agatgtcatt gacctcttgg taacaccatt cgtgacactt
     6541 ttggtcatgt ctatccttgg actctttgtc attggaccag ttttccacgt tgttgaaaac
     6601 tacatcctta ttgctacaaa agcgattctt agcatgccat ttggtcttgg tggtttcttg
     6661 attggtgggg ttcaccaatt gatcgtcgtg tcaggtgtgc accacatctt caacttgctt
     6721 gaagtgcaat tacttgctgc tgaccatgct aacccattca acgctatcat cacagctgct
     6781 atgacagctc aaggtgctgc tactgttgcg gttggtgtta aaacaaaaaa tccaaaactg
     6841 aaaacacttg ctttcccggc tgctctttct gctttcctag gtattacaga gcctgctatc
     6901 ttcggggtga acttgcgctt ccgtaaacca ttcttccttt cattgattgc tggtgcaatc
     6961 ggtggtggat tggcttctat ccttggactt gctggtactg gtaatggtat caccatcatc
     7021 cctggtacaa tgctttatgt tggtaacgga caacttccac aataccttct tatggtagct
     7081 gtatcatttg cccttggttt tgctcttact tacatgtttg gttacgaaga tgaagtagac
     7141 gcaactgcag ctgcaaaaca agctgaagtg gctgaagaaa aagaagaagt tgcgccagca
     7201 gctcttcaaa atgaaacact tgtaactcct atcgtcggtg atgttgtcgc tcttgctgat
     7261 gtcaatgacc cagtcttctc aagtggagct atgggacaag gtatcgctgt gaaaccaagc
     7321 caaggcgtgg tctatgcacc agctgatgct gaagtttcaa ttgcctttcc aacagggcac
     7381 gcttttggtt tgaaaacaag aaatggtgct gaagttttga ttcatgttgg tattgacact
     7441 gtatctatga acggtgacgg ttttgaagca aaagttgctc aaggtgataa ggtgaaagtt
     7501 ggcgatgttc ttggaacatt tgactcaaat aaaatcgcta cagctggact tgatgataca
     7561 acaatggtta tcgttacaaa tacagctgac tacgcttcag tagctccagt cgcaacaggt
     7621 tcagttgcga agggggatgc tgtgatcgaa gtgaaaatct aatcaatcct ctctaatgtg
     7681 aaaacgaaca aatgacatgt ttgttcgttt ttattagata gtaagattta cagaggaaaa
     7741 tctaaaaaat agagacattt agactttcga agtatgctat aataaagaaa ataaaaacaa
     7801 gaggtttatc atgacaaaat tatatggaag cttggaagct ggcggtacaa agtttgtctg
     7861 tgctgtcggt gatgaaaact ttaacgttgt agaaaaaaca caatttccaa caacaactcc
     7921 aatcgaaaca atcgataaaa ccattgagtt cttctcaaaa ttcgataacc ttgctggtct
     7981 tgcagttggt tcatttgggc cgattgatat tgacaaaaac tcaaaaactt atggctttat
     8041 cacgacgact ccaaaaccaa actgggcaaa tgtggacttg cttggtgccc ttcgtcgcgc
     8101 cctaaacgtg ccaatgtact tcacaacaga cgtaaacagc tctgcttacg gtgaagtggt
     8161 tgcccgtaac aatgctggtg gtcgtatcga aaacttggtt tactacacaa tcggtacagg
     8221 tatcggtgca ggcgtcatcc aacgtggtga gtttatcggt ggtgtgggtc accctgaaat
     8281 gggtcattat tatgttgcta gacacccaat ggatattgaa aaagagttta agggtgtttg
     8341 tcctttccat aagggatgtc tggaaggcta tgcagctggt ccaagtttgg aagctcgtac
     8401 aggtgtacgt ggggaaacta ttgaactcaa caaccctgtt tgggatgttc aagcctacta
     8461 tatcgctcaa gctgcggtta atgcgacagt gactttccgc ccagacgtga ttgtctttgg
     8521 tggaggggtc atggctcaac aacatatgct ggaccgtgtc cgtgagaaat ttacatctct
     8581 tcttaatggt tacctaccag taccagatgt gcgtgactat atcgtgacgc cagcagtcgc
     8641 aggaaatggt tctgccacac ttgggaactt tgttcttgca aaagaagttt caaaataaag
     8701 cacaaaatcc gcttgggaaa ccaaacggat tttttacgtg tcaaagcatt tgccagaaaa
     8761 agtcaataat ataggtcaga ccgtaggtat aaaccacgag ggtaaagggt ttggtcagaa
     8821 tgatgatggt catgtagcgc ttgaaactca tcttggtcag ggcagccagc atacagagaa
     8881 agtcagctgg gctaatgggc caaatcatca taaaaataaa gaagcggtca aaacgattgc
     8941 ccttatctag ccagccgatg tacttgtcgt aggtgcgctt gctgacgaca gactggacaa
     9001 aggcagctcc gtataggcgc actagataaa agataatggc acagccaatc acgatgccga
     9061 tatagttgta gatagtcccg atgatgtgcc cgtagataaa gaccccagcc accgaggtca
     9121 aggcccctgg aatgataggg acgacagtct gtaaaatctg taaaaagata aagagaggtg
     9181 gaccccagat gcctgcctgc tggataaagg cagagagggt ttccttggat tgtaaaatcc
     9241 cagcctgata agcccaaata cagaaaatca aactcccaac cccaccgaca atcgatgaga
     9301 tattgataac tcgctgcaaa aggggagaaa cagctttcat ttgtttatcc tgtgacatgt
     9361 aaactcctca tagatagtat atttctacta taccatattt tggaggagaa agggggaatg
     9421 agtctttttt gataaggaat agaaagtaaa tagcccttcg agacttagaa taggtctgtc
     9481 aactaaaggt tatatgcatt ctaggtttcg aataatcgca attccataaa tttaaaagca
     9541 ttctaagttt cgaatagctt atctgagata attttgaggc attcgcgctt tcgaatagtc
     9601 attttcccta aagtttagat gtattctgaa gctagaaaga ctaaaatcta aaagtagtaa
     9661 gagtctctct ctgatggacg taatttatgg ctagtatgaa tcctttgaat tgttagttaa
     9721 ttttaatatt aatcagttct gaaataatta ctaaatatag ttagatggtg aattaattat
     9781 tgctaaattt caagttcaag ttagtcatcc agaagtcttc tctgggggac ttgtagttca
     9841 agcatttttt aggatagttg ttaatccact tttcgatgaa tgcgacttcc tttgtagtcg
     9901 ttttcttagt ttcctgaggt aactatctat gaatgagcct gttgtgattt tcattagatc
     9961 ctataggggt gtgcataata gatatagcag attgaaacta gaatagtata catctacttc
    10021 taaaacattg ttagaaatca atttgactgt cctgatcaat ttgtcctgtt cttatttcat
    10081 tttactatat aatccttaga aaacatatcg gacaagcggt tgaattctgt tccgtccatt
    10141 agtagataaa ggattactcc ttcttgaaat gacagatgaa cttgtttctt ataaaaatgt
    10201 tgtctgaaac tattagcctt tttccagaag ttttagagga agaaaacttt acgaggaaaa
    10261 aggagttact caaataacaa ttcaggatta aaaatagaca gttgaggagc ggaaggtata
    10321 aattaagttt gctgctgtat aatggattta tcactaatac tcttcgaaaa tctcttcaaa
    10381 ccacgtcagc ttcgccttgc cgtacgtata gttactgact tcgtcagttc tatccacaac
    10441 ctcaaaacag tgttttgagc tgacttcgtc agttttatct gcaacctcaa agctgtactt
    10501 tgagcagtct acggctggct tcctagtttg ctctttgatt ttcattgagt ataaaagtgc
    10561 tccaggccat attttacaca gcaatagtct tctaaaaatg gacaaaaaac attgtaaagg
    10621 ctatcaaaaa ggagtataat gagtgcaaga aatttcggag gtgaaagatg ctagaagtaa
    10681 gaagtctaga gaaaagtttt ggatccaagc aagttttgtt tggtattgac tttcaagcgc
    10741 gaccaggtcg tattttggga ctagtcggaa aaaatggtgc tggaaaaaca acgattttcc
    10801 atagtatttt aaaattccta gaatatcagg gagaaatcgg tctggatggt caggatattc
    10861 gtcaggagat ctatgctcgg attggttatc tgcctgaaga acgcagtctc atgcctaaat
    10921 tgacagttct tgaacaagtt cgctacttgg cgactctaaa aggcatggat gccaaagaag
    10981 tcaaagaaaa actccctcaa tggatgaaga ggttggaagt aaaaggaaag ctgacagata
    11041 aaatcaagag tctgtcaaaa ggaaatcagc agaagattca gctcattatt actctgattc
    11101 atgaaccaga cctgattatc ttggatgagc cttttagtgg attggaccca gttaatacag
    11161 aattgctcaa acaagtcatt tttcaggaaa aagagcgcgg agcaaccatt atcttttctg
    11221 accatgtcat gaccaatgtt gaggaacttt gtgacgatat tctgatgatt cgagatggcc
    11281 gtgtggtctt gcacggacca gttcaggatg tccgcaatca atacgggaaa acgcgtctct
    11341 ttgtttcaag tgaacgaagc aaggaagaat tggaaaatct tcctcatgtc aaacaggtga
    11401 gcttgaccaa acaaggcagt tggaaattga ttttggagga tgagagcgct ggaagggaac
    11461 tcttcccaat cttgactcaa ggtcaatata tcgcaacatt tgaccaacaa gcgccaacta
    11521 tcgatgaaat ctttaaacta gaatcaggag tggaagtatg agaaatatgt gggttgtaat
    11581 caaggaaacc tatcttcgac atgtcgagtc atggagtttc ttctttatgg tgatttcgcc
    11641 gttcctcttt ttaggaatct ctgtaggaat tgggcatctc caaggttctt ctatggctaa
    11701 aaataataaa gtggcagtag tgacaacagt gccatctgta gcagaaggac tgaagaatgt
    11761 aaatggtgtt aacttcgact ataaagacga agcaagtgcc aaagaagcaa ttaaagaaga
    11821 aaaattaaaa ggttatttga ccattgatca agaagatagt gttctaaagg cagtttatca
    11881 tggcgaaaca tcgcttgaaa atggaattaa atttgaggtt acaggtacac tcaatgaact
    11941 gcaaaatcag cttaatcgtt caactgcttc cttgtctcaa gagcaggaaa aacgcttagc
    12001 gcagacaatt caattcacag aaaatattga tgaagccaag gaaaataaaa agtttattca
    12061 aacaattgca gcaggtgcct taggattctt tctttatatg attctgatta cctatgcggg
    12121 tgtaacagct caggaagttg ccagtgaaaa aggcaccaaa attatggaag tcgtcttttc
    12181 tagcataagg gcaagtcact atttctatgc gcggatgatg gctctgtttc tagtgatttt
    12241 aacgcatatt gggatctatg ttgtaggtgg tctggctgcc gttttgctct ttaaagattt
    12301 gccattcttg gctcagtctg gtattttgga tcacttggga gatgctatct cactgaatac
    12361 cttgctcttt attttgatca gtcttttcat gtacgtagtc ttggcagcct tcctaggatc
    12421 tatggtttct cgtcctgaag actcagggaa agccttgtcg cctttgatga ttttgattat
    12481 gggtggtttt tttggagtga cagctctagg tgcagctggt gacaatctcc tcttgaagat
    12541 tggttcttat attcccttta tttcgacctt ctttatgccg tttcgaacga ttaatggcta
    12601 tgcggaggga gcggaagcat ggatttcact tgctattaca gtgatttttg cggtggtagc
    12661 aacaggattt atcggacgca tgtatgctag tctcgttctt caaacggatg atttagggat
    12721 ttggaaaacc tttaaacgtg ccttatctta taaatagaag agccttgcga aagcgaggtt
    12781 tttaaaggtg aaaagggtgg aatcacgaac ctaattatgt acacattatg taaacaagtt
    12841 gcttgaaaac tcaattgtat agtgaactga atctggaata ggataatatt acttctaaaa
    12901 cattcttaca aattgatttg aattccaaaa tcccatcgtt ccgttcttat ttcattttgc
    12961 gatatagtga aaggaaataa gtcaactcac aaaaaacgca taatatcaag gatttttaac
    13021 acttgatact atgcgttttc taattttaaa gactttttgc ctggtctctt ttgttctatg
    13081 agtatgttac atatctaggt aaaaattatt taaagcaaat taaccttatt tctcaagatg
    13141 tagtaggttc cgagataaaa gatagctatg aatatgagtt ctttaacaat ggctatacct
    13201 gctcccatat agaaatggtc attgagtcct accagtgaat tgacatagaa attagaacta
    13261 atattgaaga aaagttcaat aaatccaatg acgatttgga taccaatgta ggctgcaaca
    13321 gcgagtgctg tacggtattc attgaaaagc tgtccaatgg aaatagccag gtagatgcag
    13381 aggattcctg aaatggtatt tagtaggaag gatatacctg taagaaagat ctgagggaga
    13441 tgtgtttcta caaatgtaat cacataagaa agaggaatcc attctggagc tgttaaagcc
    13501 agaataataa cagcacttag agccaataca gcggtgctaa tcaatgacca gataaaggca
    13561 ccgattagtt tggctgtgat gatatggtgt tcagaaactg gcaaggtcaa agtcagatag
    13621 ccttgtcggt cgtagacact acctttgaag cgtttaataa tcaagaaaat ggttgaaatc
    13681 gcaagtgtaa gcatcaagcc accaaagact gtagctagaa aaagtagcat agtagcctga
    13741 ctttcttggt aaggtagatt tttaaagcct tgtgtctgta ttccgatgag ggcagaaagg
    13801 actagcacgg ctgcgtagag ggctaaatac cacttgttaa catttttaaa ttcgtagtga
    13861 actaaattcc aaaacataaa taatctcctt tgcttaggcc ttaaattcct gacggaagag
    13921 ttggtcaatg gattcacctg actcgtagcg aatatcatct acatttcctt gacggacgac
    13981 ttttccgtct tttaggaaga caatttcatc caagattggc tcgatatcag aaatcaagtg
    14041 ggtagaaatc aaaacggtag aagttggtga gtagttgttg ataatggtat tgaggatata
    14101 agcacgggct gctggatcca ccccaccaat gggttcatcc aaaacataga gacgagcatc
    14161 acggctcata accaaaatca gttgaacctt ttctttgttt ccttttgata gtttcttgag
    14221 acgactattt tcatcaatgc ccaggtctgc aagtagatga tgagcgcgtt caagattgaa
    14281 atctttatag aaggtcttga agtaggttag ggcttctttg accttcattt gctcattgag
    14341 ataggtcgta tcaggcaaat aagctacaac ggccttggtt gctgggcttg ggtccatgtc
    14401 gttgatgagg acacgtcctt gatctggttg taagaggcca ttaattagtt taatcagggt
    14461 tgtttttcct gagccgtttg gcccaagaag gccgacaatt tttccagctg gaatgtcaag
    14521 agaaacattt tcaagggctg gtgttgctcc atatgatttg gatacatttt caaatgctag
    14581 taatgacata ggcttaaact cctttaatat aatcactgac tacgcctggt agttcttctt
    14641 tttcatagcc aaaatgggtc atggaggaaa cgaagtgttc caattcttct tctgataatt
    14701 gtttgcgtga ctgggcgatt agctccttat ccttagtcac aaatcgtcca gttgttcgct
    14761 tgctgtagac aaatccttct cgttcaaggt ctgataaggc tctttggatg gtattgggat
    14821 tgacaccagc ctcgctagct agctccctca cggttggaag ttgttgattg ggttccagtg
    14881 tatgggaaac aatctgaagc ttgattttct ccataatctg taaatagatg ggttttttgt
    14941 tgtcaaatgt ccaggacatc ttagtctcct ttcttttacc cttttgtctt aattgaataa
    15001 tacaacaaaa caaaaaactt gtcaagcaaa aagaagaatt gttttgggaa tcgcttaaaa
    15061 aatggtataa tgaaaagaaa acgataagga gggaaaggat gcgttgtcca aaatgtgggg
    15121 ctaccaagtc aagtgttatc gatagtcgcc aagcagaaga agggaacacc attcgtagaa
    15181 gacgtgagtg cgacgaatgc caacaccgtt ttacaaccta cgaacgagta gaagaaagaa
    15241 ccttagtggt tgttaaaaaa gatggtacac gggaacaatt ctccagagat aaaatcttta
    15301 atgggattat ccgctcagcc cagaaacgtc ctgtgtcaag tgatgaaatc aacatggtag
    15361 tcaatcgtat cgaacagaaa ctccgtggtc gaaatgaaaa tgaaattcaa agtgaggaca
    15421 ttggttcact cgtcatggag gagttggctg aattggacga gattacctat gtacgttttg
    15481 ctagtgtcta tcgtagtttt aaggatgtca gtgagttaga gagcttgctc caacaaatca
    15541 cccagtcctc taaaaagaaa aaggaaagat aaatgaagcc aattgaccgt ttttcttatc
    15601 taaagaataa tcgggtgtcg caagatacct catctctggt acagtgctac ctcccgatta
    15661 tcggtcagga ggcactgagc ctttatcttt atacaatcag tttttgggat aatggtagaa
    15721 aggaatatct tttttcaagt atcctcaatc atctcaactt tgggatggat agactgataa
    15781 aatcattgaa aatcttatct gcttttaatc tcttgaccct ctatcaaaag ggggatgttt
    15841 atcagctagc cctccatgct cctctatcta gtcaagactt cttggagcat cctgtttatc
    15901 gcagactctt agagaaaaag attggcgact ctgctgtgga ggatttgaaa gttgaaagtg
    15961 ctgatggtga agaaatacct gtctcactca atcaagtctt tccagaattg gcagaactag
    16021 gcagtcaaga agaccttggt ctcaagaaga aagtggccaa tgattttgac ttggaacatt
    16081 ttcgccagct gatggctcga gatggacttc gttttgcgga tgagcagtcc gatgtcttaa
    16141 acctctttgc tattgccgag gagaagaaat ggacttggtt tgaaacctat caattggcca
    16201 agtcaacagc tgtttctcag gttatttcaa ccaaacgcat gcgtgaaaaa attgctcaaa
    16261 aaccagtttc ctctgacttt agtcttaagg aaacaaccat tatcaaagaa gccaaaagta
    16321 aaactgccct gcagttcttg gcagaaatca agcaaacacg caagggaacc attacccaaa
    16381 cagaaagaga actcttgcaa cagatggctg gcttgggctt gctggacgaa gtcatcaata
    16441 tcattctttt attgaccttt aataaggtcg attcggcaaa tatcaatgag aaatatgcca
    16501 tgaaggtagc caatgactat gcctatcaaa agattcattc ggcagaaaag gcagtcttgc
    16561 gcatccgtga gcgaggacag aaagcaaaaa cacaaaaaca gaatcagact gccccagtaa
    16621 aaaccaatgt tcctaaatgg agtaatcctg aatataagaa tgaaaccagc gaggaaactc
    16681 gtctggaact agaacgtaag aagcaagaac tattagctcg attagaaaaa ggaggagatt
    16741 agatggaaag tgtcggagac gtactcaaac gtcaacccag ccgtttttat tatcaagatt
    16801 tggtccagaa aatcatgaag gaccctgatg ttgcggcttt tatccagcaa gaatccttga
    16861 ctccagagga attaaatcgc agtatctcca agtttaatca gtacatcacc gagcgtgaca
    16921 agtttctccg tggggatacg gattatattg ccaaaggcta caagccgatt ttggttaaga
    16981 atcatggcta tgcagatgtt tcatatgaag aaactcctga gctaatcgcg gctgaaaaag
    17041 aagcggctat taagaaccgt ctcaagttaa tcaatctacc agccagtctc aagaaagcta
    17101 gtttggctca agttgacttg gatgatttgg ggcgcttacc agtttttgaa aagctactag
    17161 ccttcgtgga gcaatatcca gctattcgaa aaggtcttta cttatatgga gactttggtg
    17221 tgggtaaaag tttcatggtg gcggccttag ctcatgattt atcagaaaaa cgtggtgttt
    17281 catcaactct cctccactat cctagctttg tcattgatgt caaaaatgct atcagtgatg
    17341 gcaatgttaa gaccttggtg gatgagatta agctgtctga ggtcctgatt ttagatgata
    17401 ttggcgccga gcaatcaacc gtttgggtgc gtgacgaaat cctgcaggtc attctccaat
    17461 atcggatgca ggaaaattta ccgacctttt tcacatccaa cttcaacttt gaagatttgg
    17521 agaagcattt tgcgaaagtg aaacatggaa atgacgaaac ctgggaagcc agacgggtca
    17581 tggaacgcat ccgttatttg gctgaggaga ctcgtttaga aggagtaaac cgtcgatgac
    17641 agaaaccatt aaattgatga aggctcatac ttcagtgcgc aggtttaaag agcaagaaat
    17701 tccccaagta gacttaaatg agattttgac agcagcccag atggcatcat cttggaagaa
    17761 tttccaatcc tactctgtga ttgtggtacg aagtcaagag aagaaagatg ccttgtatga
    17821 attggtacct caagaagcca ttcgccagtc tgctgttttc cttctctttg tcggagattt
    17881 gaaccgagca gaaaagggag cccgacttca taccgacacc ttccaacccc aaggtgtgga
    17941 aggtctcttg attagttcgg tcgatgcagc tcttgctgga caaaacgcct tgttggcagc
    18001 tgaaagcttg ggctatggtg gtgtgattat cggtttggtt cgatacaagt ctgaagaagt
    18061 ggcagagctc tttaacctgc ctgactacac ctattctgtc tttgggatgg cactgggtgt
    18121 gccaaatcaa catcatgata tgaaaccgag actgccacta gagaatgttg tctttgagga
    18181 agaataccaa gaacagtcaa ctgaggcaat ccaagcttat gaccgtgttc aggctgacta
    18241 tgctggggcg cgtgcgacca caagctggag tcagcgccta gcagaacagt ttggtcaagc
    18301 tgaaccaagc tcaactagaa aaaatcttga acagaagaaa ttattgtaga aagtgagaaa
    18361 ttatggccct accaactatt gccattgtag gacgtcccaa tgttgggaaa tcaaccctat
    18421 ttaatcggat cgctggtgag cgaatctcca ttgtagaaga tgtcgaagga gtgacacgtg
    18481 accgtattta tgcaacgggt gagtggctca atcgttcttt tagcatgatt gatacaggag
    18541 gaattgatga tgtcgatgct cctttcatgg aacaaatcaa gcaccaggca gaaattgcca
    18601 tggaagaagc agatgttatc gtctttgtcg tgtccggtaa ggaaggaatt accgatgcag
    18661 acgaatacgt agcccgcaag ctttataaga cccacaaacc agttatcctc gcagtcaaca
    18721 aggtggataa ccctgagatg agaaatgata tctatgattt ctatgctctc ggtttgggtg
    18781 aaccactgcc tatctcatct gtccatggta tcggtacagg ggatgtacta gatgcgattg
    18841 tggaaaacct tccaaatgaa tatgaagaag aaaatccaga tgtcattaag tttagcttga
    18901 ttggtcgtcc taacgttgga aaatcaagct tgattaatgc tatcttggga gaagaccgtg
    18961 ttattgccag tcctgttgct ggaacaactc gtgacgctat tgatacccac tttacagata
    19021 cagatggtca agagtttacc atgattgata cggctggtat gcgtaagtct ggtaaggttt
    19081 atgaaaatac tgagaaatac tctgttatgc gtgccatgcg tgctattgac cgttcagatg
    19141 tggtcttgat ggtcatcaat gcggaagaag gcattcgtga gtacgacaag cgtatcgcag
    19201 gatttgccca tgaagctggt aaagggatga ttatcgtggt caacaagtgg gatacgcttg
    19261 aaaaagataa ccacactatg aaaaactggg aagaagatat ccgtgagcag ttccaatacc
    19321 tgccttacgc accgattatc tttgtatcag ctttaaccaa gcaacgtctc cacaaacttc
    19381 ctgagatgat taagcaaatc agcgaaagtc aaaatacacg tattccatca gctgtcttga
    19441 acgatgtcat catggatgcc attgccatca acccaacacc gacagacaaa ggaaaacgtc
    19501 tcaagatttt ctatgcgacc caagtggcaa ccaaaccacc aacctttgtc atctttgtca
    19561 atgaagaaga actcatgcac ttttcttacc tgcgtttctt ggaaaatcaa atccgcaagg
    19621 cctttgtttt tgagggaaca ccgattcatc tcatcgcaag aaaacgcaaa taaaaaatta
    19681 gaatctggaa tgacagttcc ggattttttt gatataataa aatgatagaa aacgctatca
    19741 aaagaagggg gatgtcggtg atggaacatt tgtttaaatt cttactttta gcaccgtact
    19801 tttattttga taactggatt gaaaaggcca acagaaatag taagtttttt ccaatttttt
    19861 attattttta ctggttttac atccccttct attctctttt tagccttgct tggacagttg
    19921 tttcagttct gtttttcaat accgtcttga gaaatgtgac agatatcaag ttatggggca
    19981 tttggtttct ttttattctg ctagctattg gtatgaattg gttaacttat tcctgtttca
    20041 aagaaatgtt tcgcttgaga caggaactag ggaagtctaa gggtggaagg cattgattta
    20101 tatcggtttc tatttgtagg aggtggctta tggtacctct aaaatcattt attacacgct
    20161 attccaaggt ttatattggt aataacattt aatagaacga aactaaagaa aacaatttaa
    20221 aagaggaggt ttgtgatgga atacttgttt aaaatgataa tcttattacc ctgtttttac
    20281 tttttcagct ggattgaaaa ggcaaacaga gatagtaaga ttttcccaat tttttactat
    20341 ttttactgga tttacatcac cctctatgct ctttttagcc ttgcttggac agttttttca
    20401 gttctgtttt tcaatatcgt cttgagaaat ttgacagata tcaagttatg gggtatttgg
    20461 ctattattac tacttatcgc ttttgctagt ggctggttag actatatctg tttcaaaaaa
    20521 atgcttgact tgagacggga actagggaag tctaaaggcg gaaggcattg atttatactc
    20581 ttcgaaaatc tcttcaaacc acgtcaacgt cgccttggat tatatatgta actgacttcg
    20641 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ttgcggctag tttcctagtt
    20701 tgctctttga ttttcattga gtattatatt actttctatt tgtaggaggt ggcttatgaa
    20761 gattcctctc ttaacttttg caaggcataa atttgtttat gtcttgctta ctttgctttt
    20821 tcttgctttg gtttatcgtg atgttttgat gacttatttc ttttttgata ttcatgcgcc
    20881 cgatctagct aaattcgatg gacaagcaat taaaaatgac ttattaaaat cagcattaga
    20941 ttttcgtatt ctccagttca atctaggttt ttatcaatca tttattattc caatcatcat
    21001 tgttttgcta ggttttcaat atattgagct gaaaaataaa gttttacgat tgagtattgg
    21061 aagagaagtg agttatcaag ggttaaaaag aaagttgact ttgcaagttg caagtatccc
    21121 ttgtttgata tatttagtga ctgtgctgat aattgcaatt ataacctatt tctttgggac
    21181 tttttctcct cttggatgga attctctatt ttctgatgga agtggtttac aaagactcct
    21241 agatggagag ataaaaagct atttgttctt tacttgtgtc ctactaatcg gtattttcat
    21301 caatgcaatc tattttttac aaatagttga ttatgtgggg aatgtgactc gttcggcaat
    21361 cacctatttg atgtttcttt ggcttggttc tatgctgctc tatagtgcct tgccttacta
    21421 tatggttcct atgacgagtt tgatgcaagc tagctatggg gatgtaagtt tgatgaaact
    21481 ctttactcct tatatccttt atattgtccc ttacatggtg cttgaaaaat atgaagataa
    21541 tgtttaagaa ttttaacaat atttggctaa agagaaagat tgttttacta cttcgtatag
    21601 ttctgatgat gattttgata aaccatctat tgtcaacagc ggttcaaaag caggatgctg
    21661 ttatcttttt caagagagaa ttgatttcaa ttttttccta taatgactat tctgaagcga
    21721 atttagaaat ccccaaactc ttgttaaacc tttcgctttt catggtagga tggctctctg
    21781 tcattttact tgaaagtgat ttggcagacc attaccatca cttgattcgc tatcaatcaa
    21841 gctccttttt cgattataca aggaaacgat tggttgtcat ttctaaattt tttactcaag
    21901 atttgtttgt ctggtttctt ggtttacttc ctctaggaat tcatttcaaa acagtcgcac
    21961 ttttcttttt acttgctcag ttaatgatgt tgtacttact actgtcttat ctgatagcac
    22021 tgattagtgc gggcgctggt ttttcctttt ttctctattt tttagcattt gtgggacaag
    22081 aatggatgat ggatcatatt gtaacagtgt atttagtact cttaagctta ttagttatgt
    22141 tgattcttag tcgcttggaa gagaaattta agaaaggata aacgatgaga cttgaaatta
    22201 taaatggaca gaaaatttat gggaaaagac ctattttaaa tcagttgaat ttggtgtttc
    22261 aatcaggaaa aatttatgga cttaaaggtg ataatggatc tggcaagacg gttcttttaa
    22321 agatacttgc tggttatatt aagcttgaca aaggaaaagt tcttcaagat ggtaaagttt
    22381 acggggtaaa aaatcattat attcaggatg caggaatttt aattgaaaaa gtcgagtttt
    22441 tatctcattt atccctgaga gaaaatttgg aactgttaag gtatttttca tctaaagtta
    22501 cggaaaaaag aattgcctat tggattcaat actatgattt acaggaattt gaagatgttg
    22561 aataccgtca tttatccttg ggaacaaagc aaaaaatggc cttgattcaa gcctttattt
    22621 cctctccttc tatactcttt ctcgatgaac ctatgaatgc tttggatgag aaaagtgtga
    22681 ggttaaccaa acaggtcatt ttatcttacc tgaaaaaaga aaatggtctg gttatcctga
    22741 cgtcgcacat atcggaagat atttcagacc tttgtacaga tgtattagtt gtcgaaaatg
    22801 gacatataca atatgtaaag gatatacaat cctaggagat ggcttatggc acatctaaaa
    22861 tcatttatta cacgctattc caaggtttat attggtttag ttctgctgat ctggctgtct
    22921 ttcttcttta tcccttggga tagagcgatt ctgggggtaa ggattgacat cttcatcata
    22981 cagaaagtct tgctagtttt tggaattctg tccattttga tggccttgct gtccaagaaa
    23041 gtcagtctct ttgtttttgg actgatttgc tggctctctc tttggattaa cttatttatc
    23101 acatttgcca ttttgccgat ttttggcaat taaacagtca taaaagtcgg agaggttagc
    23161 ttgaaaacta acctcttttt ccttttcaaa atggggattc ttccttgaaa ataatcagta
    23221 attgtgctaa aattaaagga acattctaaa atattcggaa tttaaagtaa ggaaaaacat
    23281 ggctaatatt ttaaaaacaa ttatcgaaaa tgataaagga gaaatccgtc gtctggaaaa
    23341 gatggctgac aaggttttca aatatgaaga ccaaatggct gctttgactg atgaccaatt
    23401 aaaagcgaaa acagttgaat ttaaagaacg ttatcaaaat ggagaatcac tggattcatt
    23461 gctttatgaa gcatttgcgg ttgtccgtga gggtgccaaa cgtgtcctag gtctcttccc
    23521 ttataaggtt caggtcatgg gggggattgt tcttcaccat ggtgacgtgc cagagatgcg
    23581 tacaggggaa gggaaaacct tgactgcgac catgccggta tacctcaatg ccctttcagg
    23641 taaaggggtt cacgtagtta cggttaatga atacttgtca gaacgtgacg cgactgagat
    23701 gggtgaattg tactcttggc ttggtttgtc agtagggatt aacttggcta ccaaatctcc
    23761 aatggagaaa aaagaagcct atgagtgtga tattacttac tcaactaact cagaaatcgg
    23821 atttgactac cttcgtgaca atatggttgt tcgcgctgaa aacatggtac aacgtccgct
    23881 taactatgcc ttggtcgatg aggttgactc tatcttgatt gacgaggctc gtacaccttt
    23941 gattgtatca ggtgccaatg cggttgaaac cagtcagttg tatcacatgg cagaccacta
    24001 tgtaaaatct ttgaacaaag atgactacat catcgatgtg cagtctaaga ctattggttt
    24061 gtctgattca gggattgaca gggctgaaag ctacttcaaa cttgaaaacc tctatgacat
    24121 cgaaaacgtg gctttgaccc actttatcga taacgccctt cgtgccaact acatcatgct
    24181 tctcgatatt gactatgtgg tgagcgaaga gcaagaaatc ttgattgtcg accaatttac
    24241 aggtcgtacc atggaaggtc gtcgttattc tgatggattg caccaagcta ttgaagccaa
    24301 agaaggtgtg ccaatccagg atgaaaccaa gacatctgcc tcaatcacgt accaaaacct
    24361 tttccgtatg tacaaaaaat tgtctggtat gacgggtaca ggtaagactg aggaagaaga
    24421 atttcgtgaa atctacaaca ttcgtgttat tccaatccca acaaaccgtc ctgttcaacg
    24481 tattgaccac tcagaccttc tttatgcaag tatcgaatct aagtttaaag cggttgtcga
    24541 agacgttaag gctcgttacc aaaagggtca acctgtcttg gttggtacag tagcggttga
    24601 aactagtgac tacatttcta agaaattggt tgcagctggt gttcctcacg aagtcttgaa
    24661 tgccaaaaac cactatagag aagcccaaat catcatgaat gctggtcaac gtggtgccgt
    24721 taccatcgca accaacatgg cgggtcgtgg taccgacatc aagcttggtg aaggtgttcg
    24781 tgaacttgga ggactttgtg ttattggtac agaacgtcat gaaagtcgtc gtatcgataa
    24841 ccagcttcgt ggacgttcag gtcgtcaagg agatccaggt gagtcacaat tctacctatc
    24901 tcttgaagat gatttgatga aacgttttgg ttctgaacgc ttgaagggaa tctttgaacg
    24961 tctcaacatg tctgaagagg cgattgagtc tcgcatgttg acgcgtcagg ttgaagcagc
    25021 gcaaaaacgt gtcgaaggaa ataactacga tacccgtaaa caagtccttc aatacgacga
    25081 tgtcatgcgt gaacaacgtg agattatcta tactcaacgt tatgatgtca ttactgcaga
    25141 ccgtgacttg gcacctgaaa ttcaggcaat gatcaaacgc acgattggtc gtgtcgttga
    25201 cggtcatgcg cgtgctaaac aagatgagaa actagaggca attttgaact tcgctaagta
    25261 caacttgctt cctgaagatt ctattacgat ggaagacttg tcaggcttgt ctgataaggc
    25321 catcaaggaa gagcttttcc aacgtgcctt gaaggtttac gatagtcagg tttcaaaact
    25381 acgcgatgaa gaagcagtta aagaattcca aaaagttttg attctacgag tggtggataa
    25441 caagtggaca gatcatatcg atgcccttga tcaattgcgt aacgcggttg gacttcgtgg
    25501 ctatgctcag aacaaccctg ttgttgagta tcaggcagaa ggtttccgta tgtttaatga
    25561 tatgattggt tcgattgagt ttgatgtgac acgcttgatg atgaaagcac aaattcatga
    25621 acaagaaaga ccacaggcag aacgtcatat cagtacaaca gcgactcgca atatcgctgc
    25681 tcaccaagca agtatgccag aagatttgga tttgagccag attggacgca atgaactttg
    25741 cccatgtggt tctggtaaga aatttaaaaa ctgtcacggt aaaagacaat aaaatgagat
    25801 agtttagagg cggatatctt gtgaaaagta aatttttact gggtatccgt ttgctttata
    25861 aggagatgag ttatggtatt tacagcaaaa agctctaaaa taaatataga agaagttcgt
    25921 gccttgtcaa aattagaagg tcaggctttg gagaggaaat cacagcgaga tcaagagcta
    25981 gaagccatta tacgtggaga agaccagcga attctcttgg taatcgggcc atgctcatct
    26041 gacaacgaag aagctgtcct tgaatacgct aagcgtttgg cagtcctaca agaagaagtg
    26101 gcagatcgta tctttatggt tatgcgtgtt tatactgcca aaccccgtac caacggagat
    26161 ggctataagg gcttgattca ccagcctaac gcgacagaag cgcctagtct tatcaatgga
    26221 atcaaagccg ttcgccatct tcactatcgt gtcatcacag aaacagggat gacaactgct
    26281 gatgaaatgc tttatcctga aaaccttccg cttgtagatg atttgatttc ttacatggca
    26341 gttggtgccc gttcagttga agaccagcaa caccgctttg tggcaagtgg ggcaggattt
    26401 tctactggtt ttaaaaatcc aacctctgga aatctcaatg tcatgtttaa tgggatttat
    26461 gctgctcaaa acaaacaaag tttccttttc ttaggaaaag aagtagaaac aactgggaac
    26521 ccgctttcac acgctattct tcgtggtgct cttaatgagt atggaaaaaa tattcccaac
    26581 tactattatg acaatttaat tgataccatt gcccagtatg agaaaatggg tttggaaaat
    26641 ccttttatca tcattgatac caatcatgac aattctggta agcagtatat tgaacagatc
    26701 cgaattgtcc gccagacctt gattaaccgt gcttggaatg aaaaaattaa gcagttcgtt
    26761 cgtggtttta tgattgagtc ttatctggaa gatggtcgac aaaatgagcc agaagtattt
    26821 ggtaagtcta tcacagaccc ttgcctgggt tgggataaca cagaagctct tgtcagagaa
    26881 atttacaaaa cgttaggaga ataagatggc atttattgaa aaaggtcaag aaatcgatat
    26941 ggaagtcatc aaggctgaaa cccaattgtc tgcggaagcc ttgagactca aggaaagccg
    27001 tgacagggaa ttggcagata ttatttcagg ggaagatgac cgtattctct tggtgattgg
    27061 tccttgctct tctgataatg aagaggcggt cttggaatat gctcgccgtt tatccgcctt
    27121 gcaaaagaag gtagcggata agattttcat ggtcatgcgc gtgtatactg ctaagcctcg
    27181 taccaatgga gacggctata aaggattagt tcaccagcca gatacttcta aggctccaag
    27241 cctgattaac ggcttgcagg ctgtgcgcca gttgcactac cgcgtgatta cagagactgg
    27301 tttgacaacg gcagatgaga tgctttatcc gtcaaatctg atcttggtgg atgacttggt
    27361 cagctaccat gccgttggag ctcgttctgt ggaagaccaa gagcaccgct ttgtggcttc
    27421 tgggattgat gcaccagtag ggatgaaaaa tccaacctca ggaaatttgg gtgttatgtt
    27481 taacgccatc tatgctgctc aaaacaagca aaccttcctt tatcatgggc aggaagttga
    27541 gacatcaggt aatcctttgg cccatgttat cctccgtgga gcagtcaacg agtatggcaa
    27601 ttatatgccg aattactact atgaaaacct actccaagcc attgaacgct atgaaaccat
    27661 gggacttgaa aatcctttta tcctcattga caccaaccat gataactcag gcaagcaata
    27721 tatggagcag attcgaattg ttcgccagac cttgcagaat cgtgattgga atgagaaaat
    27781 taaaaagacg gttcgaggat ttatgattga atcttaccta gcagatggtc gtcaaaacca
    27841 accagaggtc tttggttgct ctattactga cccttgccta ggttgggaaa atacagaggc
    27901 cttggtagaa gagatttatg ttaccttgac aaaataagtg aaaaggatgg agttggggaa
    27961 tctcaactcc ttttgatgag aatgatagtt ggacacggaa ttgacatcga agaattggct
    28021 tcgatagaaa gcgcagttac acgacatgaa ggatttgcta agcgtgtact gaccgctcag
    28081 gaaatggagc gcttcaccag tctcaaagga cgcaggcaaa tagaatattt agctggtcgc
    28141 tggtcggcta aggaggcctt ttccaaggct atgggaacgg gcattagcaa gctcggtttt
    28201 caggatttgg aagtcttgaa caatgaacgt ggggcgcctt attttagtca ggcaccattt
    28261 tcaggaaaga tttggctgtc tatcagccac accgatcagt ttgtgacagc cagtgtcatt
    28321 ttggaggaaa atcatgaaag ctagtccaca tagaccaacc aaggctctga ttcatctggg
    28381 agctattcga caaaatattc agcaaatggg ggctcatatc cctcaaggaa cgctcaagtt
    28441 ggctgtggtc aaggccaatg cttatggtca tggagctgtt gccgttgcca aggcaattca
    28501 agatgatgtt gatggctttt gcgtttccaa tatcgatgaa gccattgaac tcagacaagc
    28561 tggactcagc aagccaatcc tcattttagg agtttctgaa atcgaagctg ttgctctagc
    28621 taaagaatat gacttcacct tgacagtggc tggactggag tggattcaag cactcttaga
    28681 taaggaagtg gacctaactg gattgacagt ccacctcaag attgattcag ggatgggacg
    28741 gattggtttt agagaggcaa gtgaggttga gcaggctcaa gatttgctcc aacaacacgg
    28801 tgtttgtgtt gaaggaatct ttacccactt tgctactgct gatgaggaat cagatgacta
    28861 ttttaatgcc cagttagaac ggtttaaaac tattttagct agtatgaagg aagttccaga
    28921 gctggttcat gctagcaatt ctgcaacgac tctttggcat gtagagacta ttttcaatgc
    28981 ggttcgtatg ggagatgcca tgtatggcct caatccaagt ggagcggtct tggatttgcc
    29041 ttatgatttg ataccggcct tgaccttgga gtctgctctg gttcatgtca agacagttcc
    29101 agctggagct tgcatgggct atggagcaac ttatcaagcg gatagcgagc aagtcatcgc
    29161 gaccgtgcca atcgggtatg cagatggatg gacaagagac atgcaaaatt tctctgtctt
    29221 ggtagatggc caagcttgcc caattgtcgg cagggtttcg atggaccaaa tcactattcg
    29281 attgcctaag ccttacccac tcggaaccaa ggtaaccttg attggctcca atggggataa
    29341 ggaaatcact gcaactcagg tagcgaccta ccgcgtaacc attaactatg aggtggtttg
    29401 cctcctcagc gaccgtattc cgagagaata ttattagaaa agaaaggagt ggagcatgaa
    29461 tctacatcaa cccttgcatg tcttgcctgg tgtgggacca aagtcagcag aaaaatacgc
    29521 caaactagga attgaaaact tgcaagatct cttgctctac tttcctttcc gttatgaaga
    29581 cttcaaaacc aagcaggtgc tgaagctgga agacggtgag aaggcagttc tttctggtca
    29641 ggtagtgact cctgctagtg tccagtatta tggtttcaag cgcaatcgcc tgcgttttag
    29701 tctcaagcag ggagaggtcg tttttgcggt gaatttcttt aaccagccct atctggctga
    29761 taaaatagag ttgggagcaa cccttgctgt ctttggaaaa tgggaccgcg ctaaggctag
    29821 tctgactggg atgaaggttc tggctcaggt agaagatgac ctccagcctg tctatcgtct
    29881 ggctcaggga atcagtcagg ccagtctggt taaggtcatc aagacggctt ttgatcaggg
    29941 actggacctc ttgatagaag aaaatctgcc ccagtcttta ctagacaaat acaaactcat
    30001 gtcccgttgt caggcagtcc gagctatgca ttttccaaag gatttggcag aatacaagca
    30061 ggctcttcgc cgtatcaagt ttgaggaact cttttatttc caaatgcagt tgcagacgct
    30121 caagtctgaa aatagagttc agggaagtgg tctggttctg aattggtctc aggaaaaagt
    30181 gacagcagtt aaagtaagtc ttccttttgc cctgacccaa gctcaggaaa agagtttgca
    30241 ggaaatttta actgatatga agtccgacca ccacatgaat cgtctcctac aaggggatgt
    30301 ggggagtgga aaaacggtag tcgctggctt ggccatgttt gcggcagtga cagcaggtta
    30361 tcaggctgcc ctaatggtac caacagaaat cctcgcagag caacactttg agagtttaca
    30421 gaaccttttt cccaatttga aactggctct cttgacaggt tccttgaaag ctgcagaaaa
    30481 gagagaggtc ttggagacca ttgccaaggg tgaggctgat ttgattatag gaactcacgc
    30541 tctgatacaa gatggggtgg agtatgctcg tcttggtttg attattatcg atgagcagca
    30601 ccgttttggt gtagggcaaa ggcgtatttt acgggaaaaa ggtgacaatc cagatgtcct
    30661 catgatgacg gcgactccca ttccacggac gcttgccatc acagcctttg gagatatgga
    30721 tgtttccatt atcgaccaga tgccagcagg tcggaagcct attgtgacgc gctggatcaa
    30781 acatgagcaa ctacctcagg tcttgacttg gttagagggg gaaattcaaa aaggttccca
    30841 agcctatgtc atctctcctt tgattgaaga atcagaagct ctagatttga aaaatgccat
    30901 tgccttatca gaggagttga cgactcattt tgcaggcaag gcagaggtgg ctcttctaca
    30961 tggtaggatg aagagtgacg aaaaagacca gatcatgcag gatttcaagg agagaaagac
    31021 ggatattctg gtttcgacga cggttattga ggttggggtc aacgttccca atgcgactgt
    31081 catgattatc atggatgccg atcgcttcgg tctcagtcaa cttcaccagc ttagaggtcg
    31141 tgtcggtcgg ggggacaagc agtcctacgc tgttctcgtt gccaatccca agacggattc
    31201 tgggaaagac cgcatgcgca tcatgacaga aacgaccaat ggatttgtcc ttgcggagga
    31261 agatttgaaa atgcgtggtt ctggtgagat ttttggaacc agacagtcag gacttccaga
    31321 gttccaagtg gctgatatta tcgaagattt tccgatttta gaagaagcaa gaaaggttgc
    31381 tagctacatt agttctatag aagcttggca agaagatcca gagtggcgca tgattgccct
    31441 tcatctggaa aagaaagaac atctggatta agctttctct aaggaaaact taagctagtt
    31501 tttaggtttg gctcttatac taaagtcatc aaaaagaaac gaggactctc atatgacagt
    31561 aacgattaaa gtaaattacc aaaccacttt ccaaaagaag gaagcaaaaa actagtataa
    31621 acagaagaga gagcgaaatg ctctttttcg tttctaaaac tactttcagc ccatcatcct
    31681 aaaagtaaag aatctaaatt cactttctat ttatccttct ttcttgcatt gattacatag
    31741 atatgctaca gttgtggtaa cgattacaaa ataaaaggag catgctatga aaaatccagc
    31801 tttgctagaa gaaattaaga cctatagagg aagggatgag gttccggaag actttgatgc
    31861 tttctgggat ggggaagtga aaaatgtttc cacacttcca tcctaccact tggaggaaag
    31921 agatttccac atttctcaag tcaagtgcta tgagttaaca tttgaaggaa gcaaggaagg
    31981 aaaggtctat gcacgcattg ttcttccaaa gagtgaggag aaggttccac taatcttcca
    32041 ttttcatggt tatatgggac gtggctggga ctgggccgac atgctggtct tcaccgtagc
    32101 tggttacggt gttgtttcca tggatgtgcg gggccagtca ggttactcac aagacggctt
    32161 gcgttctcct ttaggaaata ccgtgaaggg gcatattatc cgtggtgctg tggaaggtcg
    32221 ggaccacctc ttttataagg atgtttatct ggatatttac cagttggtcg aaattgttgc
    32281 tagtctgtct caggttgatg agaagcgtct ttctagctat ggtgcctcac aaggaggggc
    32341 tctagctcta gttgcagcag cgctcaatcc tcgaattcag aaaacagttg ccatttatcc
    32401 cttcttgtca gacttcagac gggtgattga gattggtaat actagcgagg cttacgacga
    32461 acttttccgt tatttcaagt ttcacgaccc cttccatgaa acagaggagg aaatcatggc
    32521 gacccttgcc tatatcgatg tcaaaaatct tgcccatcgt atccaaggtg aggttaagat
    32581 gattacgggc ttggacgacg atgtttgcta tcccattacc cagtttgcga tttataatcg
    32641 tctgacctgc gataaaacct atcgcatcat gcctgagtat gctcacgaag ccatgaatgt
    32701 atttgtcaat gaccaagtct acaactggct ctgtggaagt gagattcctt ttaaatatct
    32761 aaaataagga gtcgactcta agcacaaaat cttaaaaatt acaaacacgc atagtatcag
    32821 gggattaaga aaacttgata ctatgcgttt tatcatggaa atatagtaaa atgaaacaag
    32881 aacaggacaa atcgatcagg agagtcaaat cgatttctaa caatgtttta gaagtagatg
    32941 tgtactattc tagtttcaat ctattatatt tatagaattt tttgttgcta gatttgtcaa
    33001 attgcttaaa ataatttttt tcagaaagca aaagccgata cctatcgagt agggtagttc
    33061 ttgctatcgt taggcttgtc tgtaggtgtt aatacttttc aaaaatctct tcaaaccacg
    33121 tcagcttcgc cttgccgtat atatgttact gacttcgtca gttctatctg ccacctcaaa
    33181 acggtgtttt gagctgactt cgtcagttct atctgccacc tcaaaacggt gttttgagct
    33241 gactttgtca gtcttatcta caacctcaaa acagtgtttt gagcatcatg cggctagctt
    33301 cttagtttgc tctttgattt tcattgagta taaaaacaga tgagtttctg ttttcttttt
    33361 atggactata aatgttcagc tgaaactact ttcaaggaca ttattatata aaagaatttt
    33421 ttgaaactaa aatctactat attacactat attgaaagcg ttttaaaaat gaggtataat
    33481 aaatttatta acacttataa aaagtgatag aatctatctt tatgtatatt taaagataga
    33541 ttgctgtaaa aatagtagta gctatgcgaa ataacagata gagagaaggg attgaagctt
    33601 agaaaagggg aataatatga tatttaaggc attcaagaca aaaaagcaga gaaaaagaca
    33661 agttgaacta cttttgacag tttttttcga cagttttctg attgatttat ttcttcactt
    33721 atttgggatt gtccccttta agctggataa gattctgatt gtgagcttga ttatatttcc
    33781 cattatttct acaagtattt atgcttatga aaagctattt gaaaaagtgt tcgataagga
    33841 ttgagcagga agtatggtgt aaatagcata agctgatgtc catcatttgc ttataaagag
    33901 atattttagt ttaattgcag cggtgtcctg gtagataaac tagattggca ggagtctgat
    33961 tggagaaagg agaggggaaa tttggcacca atttgagata gtttgtttag ttcatttttg
    34021 tcatttaaat gaactgtagt aaaagaaagt taataaaaga caaactaagt gcattttctg
    34081 gaataaatgt cttatttcag aaatcgggat atagatatag agaggatcag tatgaatcgg
    34141 agtgttcaag aacgtaagtg tcgttatagc attaggaaac tatcggtagg agcggtttct
    34201 atgattgtag gagcagtggt atttggaacg tctcctgttt tagctcaaga aggggcaagt
    34261 gagcaacctc tggcaaatga aactcaactt tcgggggaga gctcaaccct aactgataca
    34321 gaaaagagcc agccttcttc agagactgaa ctttctggca ataagcaaga acaagaaagg
    34381 aaagataagc aagaagaaaa aattccaaga gattactatg cacgagattt ggaaaatgtc
    34441 gaaacagtga tagaaaaaga agatgttgaa accaatgctt caaatgatca gagagttgat
    34501 ttatcaagtg aactagataa actaaagaaa cttgaaaacg caacagttca catggagttt
    34561 aagccagatg ccaaggcccc agcattctat aatctctttt ctgtgtcaag tgctactaaa
    34621 aaagatgagt acttcactat ggcagtttac aataatactg ctactctaga ggggcgtggt
    34681 tcggatggga aacagtttta caataattac aacgatgcac ccttaaaagt taaaccaggt
    34741 cagtggaatt ctgtgacttt cacagttgaa aaaccgacag cagaattgcc aaatggtcga
    34801 gttcgcctct acgtaaacgg ggtattatct cgaacaagtc tgaaatctgg caatttcatt
    34861 aaagatatgc cagatgtaac gcatgtgcaa atcggagcaa ccaagcgtgc caacaatacg
    34921 gtttgggggt caaatctaca gattcggaat ctcactgtgt ataatcgtgc tttaacacca
    34981 gaagaggtac aaaaacgtag tcaacttttt aaacgctcag atttagaaaa aaaactacct
    35041 gaaggagcgg ctttaacaga gaaaacggac atattcgaaa gcgggcgtaa cggtaaacca
    35101 aataaagatg gaatcaagag ttatcgtatt ccagcacttc tcaagacaga taaaggaact
    35161 ttgatcgcag gtgcagatga acgccgtctc cattcgagtg actggggtga tatcggtatg
    35221 gtcatcagac gtagtgaaga taatggtaaa acttggggtg accgagtaac cattaccaac
    35281 ttacgtgaca atccaaaagc ttctgaccca tcgatcggtt caccagtgaa tatcgatatg
    35341 gtgttggttc aagatcctga aaccaaacga atcttttcta tctatgacat gttcccagaa
    35401 gggaagggaa tctttggaat gtcttcacaa aaagaagaag cctacaaaga aatcgatgga
    35461 aaaatctatc aaatcctcta tcgtgaggga gaaaaggaag cttataccat tcgagaaaat
    35521 ggtactgtct atacaccaga tggtaaggcg acagactatc gcgttgttgt agatcctgtt
    35581 aaaccagcct atagcgacaa gggggatcta tacaagggtg accaattact aggaaatatt
    35641 tacttcacaa caaacaaaac ttctccattt agaattgcca aggatagcta tctatggatg
    35701 tcctacagtg atgacgacgg gaagacatgg tcagcgcctc aagatattac tccgatggtc
    35761 aaagccgatt ggatgaaatt cttgggtgta ggtcctggaa caggaattgt acttcggaat
    35821 gggcctcaca agggacggat tttgataccg gtttatacga ctaataatgt atctcactta
    35881 aatggctcgc aatcttctcg tgtcatctat tcagatgatc atggaaaaac ttggcatgct
    35941 ggagaagcgg tcaacgataa ccgtcaggta gacggtcaaa agatccactc ttctacgatg
    36001 aacaatagac gtgcgcaaaa tacagaatca acggtggtac aactaaacaa tggagatgtt
    36061 aaactcttta tgcgtggttt gactggagat cttcaggttg ctacaagtaa agacggagga
    36121 gtgacttggg agaaggatat caaacgttat ccacaggtta aagatgtcta tgttcaaatg
    36181 tctgctatcc atacgatgca taatggaaaa gaatacatca tcctcagtaa tgcaggtgga
    36241 ccgaaacgtg aaaatgggat ggtccacttg gcacgtgtcg aagaaaatgg tgagttgact
    36301 tggctcaaac acaatccaat tcaaaaagga gagtttgcct ataattcgct ccaagaatta
    36361 ggaaatgggg agtatggcat cttgtatgaa catactgaaa aaggacaaaa tgcctatacc
    36421 ctatcattta gaaaatttaa ttgggacttt ttgagcaaag atctgatttc tcctaccgaa
    36481 gcgaaagtga agcgaactag agagatgggc aaaggagaga tgggcaaagg agttattggc
    36541 ttggagttcg actcagaagt attggtcaac aaggctccaa cccttcaatt ggcaaatggt
    36601 aaaacagcga ctttcctaac ccagtatgat agcaagacct tgttatttgc agtagataag
    36661 gaagatatcg gacaggaaat tattggtata gctaaaggaa gcatcgaaag tatgcataat
    36721 cttcctgtaa atctagcagg tgccagagtt cctggcggag taaatggtag caaagcagcg
    36781 gtgcatgaag ttccagaatt tacaggggga gttaatggta cagagccagc tgttcatgaa
    36841 atcgcagagt ataagggatc tgattcgctt gtaactctta ctacaaaaga agattatact
    36901 tacaaagctc ctcttgctca gcaggcactt cctgaaacag gaaacaagga gagtgacctc
    36961 ctagcttcac taggactaac agctttcttc cttggtctgt ttacgctagg gaaaaagaga
    37021 gaacaataag agaagaattc taaacatttg attttgtaaa aatagaagga gatagcaggt
    37081 tttcaagcct gctatctttt tttgatgaca ttcaggttga tacgaaatca taagaggtct
    37141 gaaactactt tcagagtagt ctgttctata aaatatagta gattgaaata agatgtgaac
    37201 aactctatca ggaaagtcaa attaatttat agaaaaattt tagcagtcaa ggtgtactgt
    37261 tatagattca atatattatg cgactattaa ccttgtcttc tcctaaaatt gactttcttg
    37321 ttttcttatc ttgtccactc gaaacaagta ttgtaagaat ttgattattt ttgaaagtac
    37381 ttttaatata cttgatatag ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga
    37441 cttgaaatgc taaaaaaaaa aaagtatact ctaattgaaa acggtaacaa aactaattta
    37501 gagaatgaaa tatagagtat ttctctctta aaagtttttg gtgaaacgag atgtagaaag
    37561 gagatttagc caaagagtct attagtgcta gaataataga ttagaattat tttagaaaaa
    37621 cgaagtgagc agcttataaa ttcaagtccc caaatagatt catactagta tcttttgcaa
    37681 aaaataaagg gcgacttcct tcatgaatat caatttcatc tataaggaag gtagctaatt
    37741 gaactaactt atttattctg tttgtcgcta gaaaaatcag acctccttgt gaagattgag
    37801 gagatactta atgaaaatca aagaagaaac tagcaagcta gtagcagatt gcccaaaaca
    37861 ccgctttgag gttgtagata agactgacgt atataatcca aggtgaagcg actgtgattt
    37921 gaagagattt tcaaagagta taggctagag agtagtgttt ttatgtcctt ctagtagaaa
    37981 atgctagaca gaagaatggg gaacttggat aggaaaaata gattgagaaa ggaggttaga
    38041 agagatgatt attacaaaaa ttagccgttt aggaacttat gtgggagtaa atccacattt
    38101 tgcaacatta atagattttc tagaaaaaac aggactagaa aatttaacag aaggttcgat
    38161 tgctatcgat ggtaatcgat tgtttgggaa ttgctttact tatctagcag atggtcaagc
    38221 aggggctttc tttgaaacac accaaaaata tttggatatt catttagttt tggaaaacga
    38281 agaagccatg gctgttacat cgccggaaaa tgtaagcgtt acccaagaat atgatgaaga
    38341 gaaagatatt gaattataca cagggaaagt ggaacagttg gttcatttga gagctggtga
    38401 atgcctcatc acttttccag aagatttaca tcaacccaag gttcgtataa atgatgaacc
    38461 tgtgaaaaaa gttgtcttta aagttgcgat ttcttaatgt agaaagagaa gaacgatgaa
    38521 aaaaatgaga aagtttttat gtctagctgg aattgcgcta gcggctgttg ccttggtagc
    38581 ttgttcagga aaaaaagaag ctacaactag tactgaacca ccaacagaat tatctggtga
    38641 gattacaatg tggcactcct ttactcaagg accccgttta gaaagtattc aaaaatcagc
    38701 agatgctttc atgcaaaagc atccaaaaac gaaaatcaag attgaaacat tttcttggaa
    38761 tgacttctat actaaatgga ctacaggttt agcaaatgga aatgtgccag atatcagtac
    38821 agctcttcct aaccaagtaa tggaaatggt caactcagat gctttggttc cgttaaatga
    38881 ttctatcaag cgtattggac aagataaatt taacgaaact gccttaaatg aagcaaaaat
    38941 cggagatgat tactactctg ttcctcttta ttcacatgca caagtcatgt gggttagaac
    39001 agatttgtta aaagaacata atattgaggt tcctaaaact tgggatcaac tctatgaagc
    39061 ttctaaaaaa ttgaaagaag ctggagttta tggcttgtct gttccgtttg gaacaaatga
    39121 cttaatggca acacgtttct tgaacttcta cgtacgtagt ggtggaggaa gcctcttaac
    39181 aaaagatctt aaagcagact tgacaagcca acttgctcaa gatggtatta aatactgggt
    39241 taaattgtat aaagaaatct cacctcaaga ttctttgaac tttaatgtcc ttcaacaagc
    39301 taccttgttc tatcaaggaa aaacagcatt tgactttaac tctggcttcc atatcggagg
    39361 aattaatgcc aacagtcctc aattgattga ttcgattgat gcttatccta ttccaaaaat
    39421 caaagagtct gataaagacc aaggaattga aacctcaaac attccaatgg ttgtttggaa
    39481 aaattcaaaa catccagaag ttgctaaagc attcttagaa gcactttata atgaagaaga
    39541 ctacgttaaa ttccttgatt caactccagt aggtatgttg ccaactatta aggggattag
    39601 cgattctgca gcctataaag aaaatgaaac tcgtaagaaa tttaaacatg ctgaagaagt
    39661 aattactgaa gctgttaaaa aaggtactgc tattggttat gaaaatgggc caagtgtaca
    39721 agctggtatg ttgactaacc aacacattat tgaacaaatg ttccaagata tcattacaaa
    39781 tggaacagat cctatgaaag cagcaaaaga agcagaaaaa caattaaatg atttatttga
    39841 ggctgttcag tagatgtaaa agactagaaa ataggtgggc tagtgagctg aaaagctcta
    39901 gcccaatctt gtaaaagaag ggagaaggag aatggttaaa gaacgtaatt taactcgctg
    39961 gatatttgtt ttgccagcta tgattatcgt aggattactc tttgtttatc cgtttttctc
    40021 gagtattttt tatagcttta ccaataagca tttgattatg cctaattata aatttgttgg
    40081 tttggctaac tataaagctg tgctatcaga tcccaacttc tttaatgcgt tctttaattc
    40141 aattaagtgg accattttct cattagttgg tcaagtttta gtagggtttg tattggcttt
    40201 agctcttcac agagtacgcc acttcaagaa attatatagg accttattga ttgttccttg
    40261 ggcatttcct accatcgtca ttgccttttc ttggcagtgg attctaaacg gggtttatgg
    40321 ctacttacct aatctaatcg taaaattagg tttaatggaa catacacctg catttttgac
    40381 agatagtaca tgggcattcc tatgtttggt gtttatcaac atttggtttg gagcaccaat
    40441 gattatggtt aatgtgcttt cagctttgca aacagtacca gaagaacaat ttgaggctgc
    40501 taagatagat ggtgcttcaa gttggcaggt gttcaagttt atcgtctttc cacatattaa
    40561 agtggttgta ggacttctag ttgttttgag aactgtatgg atctttaata actttgacat
    40621 tatctacctc attactggtg gtggaccagc caatgctaca acgacgcttc caatttttgc
    40681 ttacaacctg ggctggggaa ctaaattgtt gggtcgtgct tcagcagtta cagtattgct
    40741 ctttatcttc ttggtggcga tttgctttat ctactttgct atcatcagta agtgggaaaa
    40801 ggagggtaga aaataatgaa gaagaaatcc agtatttatt tagatattct ctcacatgta
    40861 cttttagttg gtgcgaccat cgttgcaatt ttcccattgg tatggattat catatcttct
    40921 gtcaaaggga aaggggaatt aactcagtat ccaacacgat tttggcctga acagtttaca
    40981 ttagattatt tcactcatgt tatcaacgat ttgcacttca ttgataacat tcgaaacagt
    41041 ttaatcattg ccttggctac aacccttatt gcgattatta tttctgctat ggcagcctat
    41101 ggtattgttc gattctttcc taaattggga gcaatcatgt cgagactact cgtcattacc
    41161 tacattttcc caccaatttt gttagcaatt ccctattcaa ttgccattgc taaagttggg
    41221 ttaacaaata gtttatttgg cttgatgatg gtttatctat cttttagtgt tccatatgca
    41281 gtttggctct tagttggatt tttccaaaca gttccaattg gaattgaaga agcggctaga
    41341 attgatggtg caaataaatt tgttacgttt tataaagttg tgctaccgat tgtagcacca
    41401 ggtattgtag caacagctat ttatacattt atcaatgctt ggaatgaatt cctgtatgcc
    41461 ttgattttga ttaacaatac aggaaagatg acagtagcag tagcccttcg ttcacttaat
    41521 ggttcagaaa tactagactg gggagatatg atggcagcgt ctgttattgt agttcttcca
    41581 tcaattattt tcttctctat catccaaaat aagattgcaa gtggattatc agaaggatct
    41641 gtgaagtaga cgaaagaagg aaaaaaatga ataaaagagg tctttattca aaactaggaa
    41701 tttctgttgt aggcattagt cttttaatgg gagttcccac tttgattcat gcgaatgaat
    41761 taaactatgg tcaactgtcc atatctccta tttttcaagg aggttcatat caactgaaca
    41821 ataagagtat agatatcagc tctttgttat tagataaatt gtctggagag agtcagacag
    41881 tagtaatgaa atttaaagca gatgaaccaa actctcttca agctttgttt ggcctatcta
    41941 atagtaaagc aggctttaaa aataattact tttcaatttt catgagagat tctggtgaga
    42001 taggtgtaga aataagagac gcccaaaagg gaataaatta tttattttct agaccagctt
    42061 cattatgggg aaagcataaa ggacaggcag ttgaaaatac actagtattt gtatctgatt
    42121 ctaaagataa aacatacaca atgtatgtta atggaataga agtgttctct gaaacagttg
    42181 atacattttt gccaatttca aatataaatg gtatagataa ggcaacacta ggagctgtta
    42241 atcgtgaagg taaggaacat tacctcgcaa aaggaagtat tgatgaaatc agtctattta
    42301 acaaagcaat tagtgatcag gaagtttcaa atattccctt gtcaaatcca tttcagttaa
    42361 ttttccaatc aggagattct actcaagcta actattttag aataccgaca ctatatacat
    42421 taagtagtgg aagagttcta tcaagtattg atgcacgtta tggtgggact catgattcta
    42481 aaagtaagat taatattgcc acttcttata gtgatgataa tgggaaaacg tggagtgagc
    42541 caatttttgc tatgaagttt aatgactatg aggagcagtt agtttactgg ccacgagata
    42601 ataaattaaa gaatagtcaa attagtggaa gtgcttcatt catagattca tccattgttg
    42661 aagataaaaa atctgggaaa acgatattac tagctgatgt tatgcctgcg ggtattggaa
    42721 ataataatgc aaataaagcc gactcaggtt ttaaagaaat aaatggtcat tattatttaa
    42781 aactaaagaa gaatggagat aacgatttcc gttatacagt tagagaaaat ggtgtcgttt
    42841 atgatgaaac aactaataaa cctacaaatt atactataaa tgataagtat gaagttttgg
    42901 agggaggaaa gtctttaaca gtcgaacaat attcggttga ttttgatagt ggctctttaa
    42961 gagaaaggca taatggaaaa caggttccta tgaatgtttt ctacaaagat tcgttattta
    43021 aagtgactcc tactaattat atagcaatga caactagtca gaatagagga gagagttggg
    43081 aacaatttaa gttgttgcct ccgttcttag gagaaaaaca taatggaact tacttgtgtc
    43141 ctggacaagg tttagcatta aaatcaagta acagattgat ttttgcaaca tatactagtg
    43201 gagaactaac ctatctcatt tctgatgata gtggtcaaac atggaagaaa tcctcagctt
    43261 caattccgtt taaaaatgca acagcagaag cacaaatggt tgaactgaga gatggtgtga
    43321 ttagaacatt ctttagaacc actacaggta agatagctta tatgactagt agagattctg
    43381 gagaaacatg gtcggaagtt tcgtatattg atggaatcca acaaacttca tatggcacac
    43441 aagtatctgc aattaaatac tctcaattaa ttgatggaaa agaagcagtc attttgagta
    43501 caccaaattc tagaagtggc cgtaagggag gtcaattagt tgtcggttta gtcaataaag
    43561 aagatgatag tattgattgg aaataccact atgatattga tttgccttcg tatggttatg
    43621 cctattctgc gattacagaa ttgccaaatc atcacatagg tgtactgttt gaaaaatatg
    43681 attcgtggtc gagaaatgaa ttgcatttaa gcaatgtagt tcagtatata gatttggaaa
    43741 ttaatgattt aacaaaataa aggagaaaaa catggttaaa tacggtgttg ttggagcagg
    43801 gtattttgga gctgaattgg ctcgctacat gcaaaaaaat gatggagcag agattactct
    43861 tctctatgat ccagataatg cagaggcgat tgcagaagaa ttgggagcaa aagtagcaag
    43921 ttccttagat gagttggttt ctagcgatga agtagactgt gttatcgtcg caactccaaa
    43981 taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg ttttctgtga
    44041 aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgtgt gtaaagaaaa
    44101 caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc atcatgcaaa
    44161 agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag ctcgtaatgg
    44221 ttgggaagaa caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat caggtggtca
    44281 cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg gcatgcctga
    44341 aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg gtgatgaaga
    44401 tgatatgatt tttgtcaata tggaattttc taataagcgt tttgccttgt tagaatgggg
    44461 ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag gtgccatccg
    44521 cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa gctatttctt
    44581 gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata gtacagagat
    44641 ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc tatcatctgt
    44701 cattgataaa gaaatgcgct atctgcatga gattatggaa ggagctccag tatcagaaga
    44761 atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg cagatgcttg
    44821 tacccagtct atgtttgaag atcgcaaagt aaaattgtca gaaattgtaa aataaatttt
    44881 ggtattctcc tatttatagg tcgacttgct cctctgaaag tacttttaga ggagctgttt
    44941 gactttgcta gtttttgaaa ctgaaatcta ttatactaca aactattgaa agcgttttaa
    45001 ttttaaggta taataatctc atagaaataa agaaaaggag gaaagaggat gccacagatt
    45061 agcaaagaag ccttgattga gcaaatcaaa gatggaatca tcgtttcttg tcaggctctt
    45121 cctcatgaac cgctttatac agaagcggga ggggtgattc ccttgctggt caaagcggct
    45181 gagcaaggtg gagcagtcgg tatccgagca aacagtgttc gcgatatcaa ggaaattaag
    45241 gaagtcacta aacttccaat cattgggatt atcaaacgtg attatccacc tcaggaaccc
    45301 ttcatcacgg ctactatgaa agaagttgat gaattggcag aactggacat cgaggtgatt
    45361 gctctggatt gtaccaagcg tgaacgctac gatggtttgg aaattcaaga gttcattcgt
    45421 caggttaagg agaaatatcc taatcagctt ttgatggctg atactagtat cttcgaagaa
    45481 gggctagcag ctgtagaagc aggaattgac tttgtcggaa caaccttatc aggctacaca
    45541 tcctacagtc caaaagtaga tggtccagat tttgaattga ttaagaaact ctgtgatgcc
    45601 ggtgtagatg tcattgcaga aggaaaaatt catacaccag aacaagccaa acaaatcctt
    45661 gaatatggag tgcgaggcat cgttgttggt ggcgccatta ctagaccaaa agagattaca
    45721 gaacgcttcg ttgctagtct taaataagat gtgagaggga gttttatgtt taaagtttta
    45781 caaaaagttg gaaaagcttt tatgttacct atagctatac ttcctgcagc aggtctactt
    45841 ttggggattg gtggtgcact ttcaaaccca accacgatag caacttatcc aatactagac
    45901 aatagtattt ttcaatcaat attccaagta atgagctctg caggagaggt tgtattcagt
    45961 aatttgtcac tacttctctg tgtgggatta tgtattggct tagcgaaacg agataaagga
    46021 accgctgcgt tagcaggagt aactggttac ttagttatga ctgcaacgat caaagctttg
    46081 gtaaaacttt ttatggcaga aggatctgca attgatactg gattattgga gcattagttg
    46141 tcggaatagt tgccgtatat ttgcacaacc gatataacaa tattcaatta ccttccgctt
    46201 taggattctt tggaggttca cgcttcgttc ctattgttac atcgttctct tctatcttga
    46261 ttggctttgt cttctttgtt atttggccac ctttccaaca acttcttgtt tctacaggtg
    46321 gatatatttc tcaggcgggt ccaattggaa cttttctata tggattttta atgagacttt
    46381 ctggagcagt aggcttacat catataattt accctatgtt ttggtatact gaacttggtg
    46441 gtgttgaaac tattgcagga caaacagtgg ttggagctca aaaaatattt tttgctcaat
    46501 tagccgatcc ggcccattct ggattattta cagaaggaac aaggtttttt gcaggtcgtt
    46561 tctcaacaat gatgttcggt ttaccggctg cctgtttagc gatgtaccat agtgttccta
    46621 aaaatcgtcg taaaaaatac gcgggtttgt tttttggagt tgctttaaca tcttttatta
    46681 ccggtattac agaaccaatt gaatttatgt ttctattcgt cagtccggtt ctatatgttg
    46741 ttcacgcatt ccttgatggt gttagcttct ttattgcaga cgtcttaaat atttcaatag
    46801 gaaacacatt ttcaggaggt gtaatcgatt tcactttatt tggaattttg caggggaacg
    46861 ctaagacgaa ttgggttctt cagattccat ttggacttat ttggagtgtt ttgtattata
    46921 ttatttttag atggttcatt actcaattca acgttctaac gccaggacga ggagaagaag
    46981 tagattctaa agaaatttct gaatccgcag attcaacttc aaatactgca gattatttaa
    47041 aacaggatag cctacaaatt atcagagcct tgggtggatc aaataatata gaagatgtag
    47101 atgcttgtgt gacacgttta cgtgtagctg taaaagaagt taatcaagtt gataaagcac
    47161 ttttaaaaca aattggtgca gttgatgtct tagaagtgaa gggtggcatt caagcaatct
    47221 atggagcaaa agcaatctta tataaaaata gtattaatga aattttaggt gtagatgatt
    47281 aagtacttac tgacttaata aaaaacagag gagagtgatg gatgagtagg atgaaatgaa
    47341 atcgcataca agaaataaag aactcattat ccaagttgga tacgcttatt acataggaga
    47401 atacaaatga aatttagaaa attagcttgt acagtacttg cgggtgctgc ggttcttggt
    47461 cttgctgctt gtggcaattc tggcggaagt aaagatgctg ccaaatcagg tggtgacggt
    47521 gccaaaacag aaatcacttg gtgggcattc ccagtattta cccaagaaaa aactggtgac
    47581 ggtgttggaa cttatgaaaa atcaatcatc gaagcgtttg aaaaagcaaa cccagatata
    47641 aaagtgaaat tggaaaccat cgacttcaag tcaggtcctg aaaaaatcac aacagccatc
    47701 gaagcaggaa cagctccaga cgtactcttt gatgcaccag gacgtatcat ccaatacggt
    47761 aaaaacggta aattggctga gttgaacgac ctcttcacag atgaatttgt taaagatgtc
    47821 aacaatgaaa acatcgtaca agcaagtaaa gctggagaca aggcttatat gtatccgatt
    47881 agttctgccc cattctacat ggcaatgaac aagaaaatgt tagaagatgc tggagtagca
    47941 aaccttgtaa aagaaggttg gacaactgat gattttgaaa aagtattgaa agcacttaaa
    48001 gacaagggtt acacaccagg ttcattgttc agttctggtc aagggggaga ccaaggaaca
    48061 cgtgccttta tctctaacct ttatagcggt tctgtaacag atgaaaaagt tagcaaatat
    48121 acaactgatg atcctaaatt cgtcaaaggt cttgaaaaag caactagctg gattaaagac
    48181 aatttgatca ataatggttc acaatttgac ggtggggcag atatccaaaa ctttgccaac
    48241 ggtcaaacat cttacacaat cctttgggca ccagctcaaa atggtatcca agctaaactt
    48301 ttagaagcaa gtaaggtaga agtggtagaa gtgccattcc catcagacga aggtaagcca
    48361 gctcttgaat accttgtaaa cgggtttgca gtattcaaca ataaagacga caagaaagtc
    48421 gctgcatcta agaaattcat ccagtttatc gcagatgaca aggagtgggg acctaaagac
    48481 gtagttcgta caggtgcttt cccagtccgt acttcatttg gaaaacttta tgaagacaaa
    48541 cgcatggaaa caatcagcgg ctggactcaa tactactcac catactacaa cactattgat
    48601 ggatttgctg aaatgagaac actttggttc ccaatgttgc aatctgtatc aaatggtgac
    48661 gaaaaaccag cagatgcttt gaaagccttc actgaaaaag caaacgaaac aatcaaaaaa
    48721 gctatgaaac aatagtcctt agttattcta taaaaagtag ttttttaaag aacctaagag
    48781 tgtatacccc cttttccctc tacacagata gtgtaagaaa agggggcttt tgtttaaaat
    48841 gtaagaaact gtcacgaaat taaaatgaag ttcttacata agcgaatcat aaaaaatttc
    48901 attttgattt taaaacagtt caagaaagtc aaaaaattat tctatttgaa agagaggtgc
    48961 cgactgtgaa agtcaataaa atccgtatgc gggaaacagt gatttcctac gctttcctag
    49021 caccagtatt attcttcttt gtcatctttg tgttggctcc gatggtgatg ggcttcatta
    49081 caagtttctt taactactca atgactaaat ttgagtttgt aggcttggat aactatatcc
    49141 gtatgtttaa agatcctgtc tttacaaaat ctctgattaa cacagttatt ttggttattg
    49201 gatctgtacc agttgttgtt ctattctcac tctttgtagc atctcagacc tatcatcaaa
    49261 atgtcattgc cagatccttc taccgtttcg tcttcttcct tcctgttgta acgggtagtg
    49321 ttgccgtgac agttgtttgg aaatggattt atgacccact atcagggatt ctaaactttg
    49381 tccttaagtc aagccacatc atcagccaaa acatttcttg gttgggagat aaaaactggg
    49441 cattgatggc gattatgatt attctcttga ccacttcagt tggtcagccc atcatccttt
    49501 atatcgctgc catggggaat attgacaatt cactggttga agcggcgcgt gttgatggtg
    49561 caactgagtt tcaagttttc tggaagatta aatggccaag ccttcttcca acaactcttt
    49621 atattgcaat catcacaaca attaactcat tccagtgttt cgccttgatt cagcttttga
    49681 catctggtgg tccaaactac tcaacaagta ccttgatgta ctacctttac gaaaaagcct
    49741 tccaattgac agaatacggc tatgccaaca caattggtgt cttcttggca gtcatgattg
    49801 ctatcgtaag ctttgttcaa tttaaagtac ttggaaacga cgtagaatac taaagaaagg
    49861 agacagctat gcaatctaca gaaaaaaaac cattaacagc ctttactgtt atttcaacaa
    49921 tcattttgct cttgttgact gtgctgttca tctttccatt ctactggatt ttgacagggg
    49981 cattcaaatc acaacctgat acaattgtta ttcctcctca gtggttccct aaaatgccaa
    50041 ccatggaaaa cttccaacaa ctcatggtgc agaaccctgc cttgcaatgg atgtggaact
    50101 cagtatttat ctcattggta accatgttct tagtttgtgc aacctcatct ctagcaggtt
    50161 atgtattggc taaaaaacgt ttctatggtc aacgcattct atttgctatc tttatcgctg
    50221 ctatggcgct tccaaaacaa gttgtccttg taccattggt acgtatcgtc aacttcatgg
    50281 gaatccacga tactctctgg gcagttatct tgcctttgat tggatggcca ttcggtgtct
    50341 tcctcatgaa acagttcagt gaaaatatcc ctacagagtt gcttgaatca gctaaaatcg
    50401 acggttgtgg tgagattcgt accttctgga gtgtagcctt cccgattgtg aaaccagggt
    50461 ttgcagccct tgcaatcttt accttcatca atacttggaa tgactacttc atgcaattgg
    50521 taatgttgac ttcacgtaac aatttgacca tctcacttgg ggttgcgacc atgcaggctg
    50581 aaatggcaac caactatggt ttgattatgg caggagctgc ccttgctgct gttccaatcg
    50641 tcacagtctt cctagtcttc caaaaatcct tcacacaggg tattactatg ggagcggtca
    50701 aaggataata ctctgcgaaa atcgaatgca aactacgtca gcttcacctt gccatactta
    50761 agtattgcct gcggttagct tcctagtttg ttcttcaatt ttcattgagt ataggaaaat
    50821 caatctatca agatacagaa gtatatttta tagatttaga gaatatagag gttataagtg
    50881 tctacaaaat ggagggtatg cagttacttt atgaagtttt gtcagacact tatcaactta
    50941 agaatggttt tagttaacta tcagaaacga aggaaagagt atgatttttg acgatttgaa
    51001 aaacatcacc ttttacaaag ggattcatcc caatttagac aaggctatcg actacctcta
    51061 ccaacaccgt aaagattcat tcgaattagg aaagtatgag attgatggag ataaagtctt
    51121 tctagttgtt caggaaaatg tcctcaatca agttgagaat aatcaatttg aacaccataa
    51181 gaactatgca gatttgcatt tgctgataga agggcatgaa tattcgagct acggttcacg
    51241 tatcaaagac gaggcagtag cattcgacga agcgagtgac attggctttg ttcattgtca
    51301 tgaacactac ccgctcttgt tgggttatca caattttgcg attttcttcc caggtgagcc
    51361 acatcagcca aatggttatg caggcatgga agaaaaggtt cgaaaatatc tctttaaaat
    51421 cttgattgat taaaaatagg atgaattgtt tttttgtaaa gctttgataa tactctacca
    51481 tgaaattgat ctttgtgagg tagagaaatg agaataaaat atttaaaaat tggtatcttc
    51541 taagtatgct gcaagagcta gtttcttaga tggacagggg attacagttg atgagatgtc
    51601 ctggataatt aggggcattg tgaatggatt gattggtaga tacataaaat taggtactta
    51661 tgcagctaag tatggtatta gtatggcgcg ctcgatctta agtagggcag ctgcaactgc
    51721 ggcagcaaga gtaagattat tgactaagat ttttggatgg attttacgaa tagctgtgct
    51781 cgcagctgat gtatatggta attttgccaa caatattgct gcagcttggg atgcacatga
    51841 taaaatccct aacaatggtc gtataaactt ttaaaatgcg agaatgaaag cactttgtat
    51901 ttttttattg tatatgttag cttggacagt gcttgcaatg ataatccgtg gagggctaga
    51961 tggatttgat gaacacactt ggcgtaatat tttagctagt gcgttgtcct cgctatacat
    52021 acattatata tccatagata gaaaaagaaa aaagtccaaa agaaaaaaga aaaaatagat
    52081 ttgttcatgg tagggactta tgaaagcttt actaacaaaa aagaaaacag tttacaaaga
    52141 aaaatgatgg aggagtaaac atggcacaaa aaggagtaag ccttatcaag gcagcatttg
    52201 atacagataa ctttcttatg cgttttagtg agaaagtctt ggacatcgtg acagccaatc
    52261 ttctttttgt cgtctcttgt ttgcccatcg tgacgattgg agtggctaaa atcagcctct
    52321 acgagaccat gtttgagatt aagaagagca gacgggtgcc tgtttttaaa atctatctaa
    52381 gatctttcaa gcaaaatctg aaactaggtc ttcagttagg tctgcttgag ttgggcattg
    52441 tttcattaag cctcctagat ctttatctct tttggggtca aacagctctg ccctttcaat
    52501 tgctgaaagc tatttgtcta ggcattctga ttttccttac gattgtgatg ttggctagct
    52561 atccaatcgc ggcacgttat gatttaactt ggaaagaagt gttacaaaaa gggcttatct
    52621 tggcaagttt taactttcct tggttcttcc tcatgttagc cattcttgtc ctcattgtga
    52681 tggttcttta tctgtccgcc ttcagtctac tcttaggtgg ctcagtcttc ctactttttg
    52741 ggtttggact attggtcttt atccagactg gattgatgga gaaaattttc gcaaaatacc
    52801 aataggagcc ttatttctga aactactttc aaaggctcca aacgctattc tataagcgag
    52861 aaactaaaat ctaagtgtct ataagatatt gaaagccttt tcggtaaagt gtatactaaa
    52921 gaagtaaaga aaaatctgct ttagcagaaa ataaaaataa taggagaaaa tctatgtcag
    52981 atttgaaaaa atacgaaggt gtcattccag ccttctacgc atgttatgat gatcaaggag
    53041 aagtaagctc agaacgtacg cgtgccttgg ttcaatactt cattgataaa ggtgttcaag
    53101 gtctttatgt caatggttct tctggtgaat gtatctacca aagcgttgaa gatcgcaagt
    53161 tgattttgga agaagtcatg gcggtagcta aaggtaaatt gaccattatt gcccatgttg
    53221 cctgcaacaa tactaaagac agtatggaac ttgctcgcca tgctgaaagc ttgggagtag
    53281 atgctattgc aacgattcca ccaatttatt tccgcttgcc agaatactca gttgccaaat
    53341 actggaacga tatcagttct gcagctccaa acacagacta cgtgatttac aacattcctc
    53401 aattggcagg ggttgctttg actccaagcc tttacacaga aatgttgaaa aatcctcgtg
    53461 ttatcggtgt gaagaactct tctatgccag ttcaagatat ccaaaccttt gtcagccttg
    53521 gtggggaaga tcatatcgtc tttaatggtc ctgatgagca gttcctagga ggacgcctca
    53581 tgggggctag ggctggtatc ggtggtactt atggtgctat gccagaactc ttcttgaaac
    53641 tcaatcagtt gattgcggat aaggacctag aaacagcgcg tgaattgcag tatgctatca
    53701 acgcaatcat tggtaaactc acttctgctc atggaaatat gtacggtgtc atcaaagaag
    53761 tcttgaaaat caatgaaggc ttgaatattg gatctgttcg ttcaccattg acaccagtaa
    53821 ctgaagaaga tcgtccagtt gtagaagcgg ctgcagcctt gattcgtgaa accaaggagc
    53881 gcttcctcta atctaaaagg aggtatttat gacatactac gttgcaattg atatcggtgg
    53941 aactaacatc aagtatggtt tggttgatca agaggggcaa cttcttgaat cgcatgaaat
    54001 gccaactgag gcgcataagg gtggacctca tatcttacaa aagaccaaag atatcgtagc
    54061 tagttattta gaaaaaggcc cagtagcagg tgttgccata tcttctgctg ggatggtgga
    54121 tccggataag ggtgagattt tctatgctgg gccgcaaatc cctaactacg caggcaccca
    54181 gttcaaaaag gaaatcgaag aaagctttac tattccttgt gagattgaaa atgatgtcaa
    54241 ctgtgcaggt cttgctgagg cagtatctgg ttcaggcaag ggagcaagtg tgacactttg
    54301 cttgaccatt ggaacaggta tcggtggttg cttgattatg gataggaaag tcttccatgg
    54361 ttttagtaat tcagcctgtg aagtcgggta tatgcatatg caggatggag cttttcaaga
    54421 cttggcttct acaacagctt tagtgaaata tgtagctgaa gcccatggag aagatgttga
    54481 tcagtggaat ggccgacgta tctttaagga agctactgaa ggaaacaaaa tctgcatgga
    54541 aggtattgac cgtatggttg actatctagg aaaaggtctg gcaaatattt gctacgttgc
    54601 caatccagaa gtggtcattc ttggtggtgg tatcatgggg caagaggcta tcctcaaacc
    54661 taagatccgc acagccttga aagaggcttt ggtaccaagt ttagcagaaa aaacacgatt
    54721 agaatttgcc catcaccaaa atacagcagg gatgttgggt gcatattatc attttaagac
    54781 aaaacaatcc tagtttggct cagccaaact aggattttct tacacgtttt tgtctacgat
    54841 agccgttgag ttttttattt tcccagtagc tattaaagat tttttccttg ctttcgcgat
    54901 tgatttccaa aaagtaggca taaatcaaat cgataaagaa gagcatagga agttgagcgg
    54961 atattcgttg gatataggag ggttggctgt gggtggctac aagaacagtc tctgtatagg
    55021 tctggctatc tttattggga acacttgtaa agagtacagt ctttgccccc atctccttgg
    55081 catctaatag actatctaaa atagaaggag ttgagcctga aagtgagaag cccagtacta
    55141 gacaattttc atccatgatg ctggttgtcc aggcaaagcc gtcttggtct gtcaaagctt
    55201 cgcagaccac acctagtcgc ataaaacgta atttcatttc acgggcgacg aggccagaac
    55261 tccctgttcc aaagaagtag atacgctcag catcttcgat tagctgggca attcgctcta
    55321 gttggatttc gtcaatcaag tcttgtgttt gttccctcat attgctataa cttctgagga
    55381 ctcgtttggt cagtggactg tgcttggaga cttggttggc ttgattttct gcctgatgtt
    55441 ggtattggaa aataaattct cggtagccag taaagccaca ctttttagca aagcgggtca
    55501 aagcagcttg agaaatatgt aatttttggg tgacttgttg agaagataaa tcatctgtaa
    55561 tcgtttcagc ttgcaaaaaa tagcgagcga tttcttgctc taggtctgtc atttcttcaa
    55621 aatgtgaatc aatgatagtt gcgatatctg gtttgtccat agggaaagct cctttacatg
    55681 agtcatactg gaagactaga tcagggaata gtcacacttc attataacac ataatataag
    55741 gatagataaa taaaaacgca tttctgtttt aaaaacgaaa aaatcgaaaa agcttctttc
    55801 ttttccataa ttttctactc aaattgtggt acaattaaga gtaagatttt aagttagaaa
    55861 tgagactgat ttgtatgaga aaatttaaca gccattcgat tccgattcgg cttaatttat
    55921 tgttttcaat cgtcatttta ctctttatga ccattattgg tcgtttgttg tatatgcagg
    55981 ttttgaacaa ggatttttac gaaaaaaagc tagcctcagc tagtcagacc aagattacaa
    56041 gcagttcagc ccgtggggaa atttatgatg ctagtggaaa acctttggta gaaaatacgt
    56101 taaagcaggt tgtttccttt acgcgtagca ataaaatgac ggctacagac ttaaaagaaa
    56161 cagctaaaaa gttactgact tatgtgagca tcagttctcc aaatttgaca gaacgccagc
    56221 tggcggatta ctatttggct gatcctgaaa tctataaaaa aacagtggaa gctctcccaa
    56281 gtgagaaacg cttggattca gatggcaatc gtctatccga atcagaactg tataacaatg
    56341 cggtcgatag tgtccaaaca agtcaactaa actatacaga ggatgaaaag aaagaaatct
    56401 atctttttag tcagttaaat gctgttggaa actttgcgac aggaaccatt gctacagatc
    56461 ctctaaatga ttctcaggtg gctgttattg cctctatttc aaaggagatg cctggcatta
    56521 gtatttctac ttcttgggat agaaaggttt tggaaacttc cctttcttct atagttggga
    56581 gtgtatccag tgaaaaagct ggtctcccag cggaagaagc agaagcctat cttaaaaaag
    56641 gctattctct aaatgatcgt gttggaacct cctatttgga aaagcaatat gaagagacct
    56701 tacaagggaa acgctcggta aaagaaatcc atctggataa atatggcaat atggaaagtg
    56761 tggatacaat tgaggaaggt agtaagggaa acaatatcaa gctgaccatt gatttggcct
    56821 tccaagatag cgtggatgct ttgctgaaaa gttatttcaa ttccgagcta ggaaatggtg
    56881 gagccaagta ttctgagggt gtgtatgcag tcgcccttaa ccccaaaaca ggtgctgttt
    56941 tgtctatgtc aggactcaaa catgacctga aaacgggaga gttgactcct gattccttgg
    57001 gaacggtaac caatgtcttt gtcccaggtt cggttgtcaa ggctgcgacc atcagctctg
    57061 gctgggaaaa tggagtctta tcaggaaacc agaccttgac agaccagtcc attgtctttc
    57121 aaggttcagc tcccatcaat tcttggtata ctcaggctta cggttcattc cctatcacag
    57181 cagtccaagc tctggagtat tcatctaatg cctatatggt ccaaacagct ttaggtctta
    57241 tggggcagac ctaccaacct aatatgtttg tcggcaccag caacctagag tctgctatgg
    57301 ggaaattgcg ttcaaccttt ggtgaatatg gtttgggttc tgcgaccggg attgacctac
    57361 cagatgaatc tactggattt gttcccaaag actatagctt tgctaattac atcaccaatg
    57421 cctttgggca gtttgataac tatacgccga tgcagttggc tcagtatgta gcaactattg
    57481 caaatgatgg tgttcgtgtg gctcctcgta ttgttgaagg catttatgga aataatgata
    57541 agggaggcct aggcgacttg attcagcaac tgcaaccgac agagatgaat aaggtcaata
    57601 tatccgactc tgatatgagt attttgcacc aaggttttta tcaggttgct catgggacta
    57661 gtggattgac aactggacgt gccttttcaa atggcgcagc ggtatccatt agtggaaaaa
    57721 caggtactgc cgaaagttat gttgagggtg gtcaagaagc taacaatact aatgctgtgg
    57781 cctatgcacc atcagataat cctcaaatcg ctgtagctgt tgtcttccct cataacacca
    57841 accttacaaa tggtgtcgga ccttccattg cgcgcgatat tatcaacctc tataaccaac
    57901 atcatccaat gaattagaaa ggaacatatg ctttatccaa cacctattgc taagttgatt
    57961 gacagttatt ctaagttacc aggtatcggg attaagacgg ctacgcgtct ggccttttat
    58021 acgattggga tgtctgctga tgatgtcaat gaatttgcaa aaaatctcct ttctgctaag
    58081 agagaattga catattgttc tatttgtgga cgtttgacag acgacgatcc ttgttctatc
    58141 tgtactgatc cgactcgtga ccagacaaca attttagttc ttgaggatag tagagatgtg
    58201 gcagccatgg aaaatatcca agaataccat ggactctatc atgtccttca tggcctcatt
    58261 tctcctatga atggtatcag tccggacgat atcaatctca agagccttat gactcgtctt
    58321 atggatagtg aagtttcaga agtgattgtg gcgactaatg ctacagcgga tggtgaagcg
    58381 acttccatgt atctttcacg tttgctcaag ccggctggta tcaaggttac gcgtctagca
    58441 cgaggtctcg ctgtgggagc ggacattgag tatgcggacg aagtgacact cttacgagcg
    58501 attgaaaatc ggacagagtt gtaagtgtag gcaaatttac gaactccatt catttataaa
    58561 aaatcaaaga ggctgaaaat cgttcctatc ggcctctttt tgtatagtgt gatgagtagg
    58621 atcaggttca agttttaaaa aaccaagcaa atatgatata ctaaagagcg agtattctag
    58681 tagaattagg acaaataata tgaaacaaac gattattctt ttatatggtg gacggagtgc
    58741 ggaacgcgaa gtctctgtcc tttcagctga gagtgtcatg cgtgcggtca attacgaccg
    58801 tttcacagtc aagactttct ttatcagtca gtcaggtgac tttatcaaaa cacaggaatt
    58861 tagtcatgct ccggggcaag aagaccgtct catgaccaat gaaaccattg attgggataa
    58921 gaaagttgca ccaagtgcta tctacgaaga aggtgcagtg gtctttccag tccttcacgg
    58981 gccaatggga gaagatggct ctgttcaagg attcttggaa gttttgaaaa tgccttacgt
    59041 tggttgcaac attttgtcat caagtcttgc catggataaa atcacgacta agcgtgttct
    59101 ggaatctgct ggtattgccc aagttcctta tgtggctatc gttgaaggcg atgatgtgac
    59161 tgctaaaatc gctgaagtgg aagaaaaatt ggcttatcca gtcttcacta agccgtcaaa
    59221 catggggtct agtgtcggta tttctaagtc tgaaaaccaa gaagaactcc gtcaagcctt
    59281 aaaacttgcc ttccgatatg acagccgtgt cttggttgag caaggagtga atgcccgtga
    59341 aattgaggtt ggcctcttgg gtaactacga tgtcaagagc acgctacctg gagaagttgt
    59401 caaggacgtt gccttttatg actacgatgc caagtatatt gataacaaga ttactatgga
    59461 tattcctgcc aaaatcagtg atgatgtggt ggctgtcatg cgtcaaaatg cagaaacagc
    59521 cttccgtgcc attggtggcc ttggtctatc tcgttgcgat ttcttctata cagataaggg
    59581 agagattttt ctcaacgagc tcaataccat gccaggtttt acccagtggt ctatgtaccc
    59641 actactttgg gacaatatgg ggatcagcta cccagaacta atcgagcgtt tggttgacct
    59701 tgccaaggaa agttttgaca agcgcgaagc gcatttgata taaaatgaaa gagagggtag
    59761 aagccagaac catcactgca cggtgactag agttctcgga cttcagccct ttttaaagga
    59821 gtagaaatga aattaacaat ccatgaaatt gcccaagttg ttggagccaa aaatgatatc
    59881 agtatctttg aggacaccca gttagaaaaa gctgagtttg atagtcgttt gattggaact
    59941 ggagatttat ttgtgccact taaaggtgcg cgtgatggcc atgactttat tgaaacagcc
    60001 tttgaaaatg gtgcagcagt aaccttgtct gagaaagagg tctcaaatca tccttacatt
    60061 ctagtagatg atgttttgac agcctttcaa tccctagcat cctactatct tgaaaaaacg
    60121 actgttgatg tctttgctgt tacaggttca aatggcaaga caacgactaa ggatatgttg
    60181 gcgcatttac tgtcaacaag atacaagacc tacaaaacac aaggcaatta caataatgag
    60241 attggccttc cttacacagt tctccacatg cctgaaggaa cagaaaagtt ggtcttggag
    60301 atggggcagg accacttggg agatattcat ctcttgtctg aattggctcg tccaaaaaca
    60361 gccatcgtga ccttggttgg agaagctcat ttggcctttt tcaaagatcg ttctgagatt
    60421 gctaaaggaa aaatgcaaat tgcagacgga atggcttcag gttccttgct tttagcgccg
    60481 gctgacccta tcgtagagga ctatttgcca actgataaaa aggtggttcg ttttggtcaa
    60541 ggagcagagc tggaaattac tgacttggtt gagcgcaaag atagtctgac cttcaaggcc
    60601 aatttcttag agcaagtcct tgatttgcca gtaactggca agtataatgc gacaaatgct
    60661 atgattgcat cctatgttgc cttgcaagaa ggagtttcag aggagcaaat tcatcaggcc
    60721 ttccaagatc ttgaattgac gcgtaaccgt accgaatgga agaaagcagc caatggagca
    60781 gatatcctgt ctgatgtata caatgccaat ccaactgcta tgaagttgat tttagagact
    60841 ttctctgcca ttccagccaa tgaaggtggc aagaaaattg cggttttagc ggacatgaag
    60901 gaactgggta accagtcagt tcaacttcat aatcagatga ctttgagcct ttctccagat
    60961 gtgcttgata ccgtgatttt ctatggagaa gacattgctg aattagccca attggccagt
    61021 caaatgttcc caattggcca cgtttactac ttcaagaaaa cagaagacca agaccaattt
    61081 gaagacctag tcaagcaggt caaggaaagc ctcagtgcca atgatcaaat cttgctcaag
    61141 ggctctaact ctatgaacct agctatgttg gtagaaagtt tagaaaatga aaccaagtga
    61201 ttttgttaag tatctgcaaa gaatgattgc ccttacagat actggcttaa cctttacaaa
    61261 agatcctttt gaccgtgagc gctacgagga cttgcgaagt ctgttatctg aaatgttgaa
    61321 tcagggatca gacctggatg cagaagaagt agcagaagtc ttgaaaccaa cttcagctta
    61381 tgcgactccc ttaatggacg tccgtgcttg gattgttgag gatgagaaga tttgtctggt
    61441 taggggacaa ggagagggta gttgggcttt gccaggtggc tttggtgaag tcggctattc
    61501 tccaactgaa aatattctca aggaaattga agaagaaacc ggttttaaag tcaaagttga
    61561 aagactgcta gctgtttttg atatcaatcg tttccaacta cagagcaaac aatatgcaaa
    61621 gtttgttttt gaatgtaagc ttctcgatgg acaattccaa gaaaatcaag aaattgcaga
    61681 ccttcaattt tttgccattg atcaactgcc agtcttatct gaaaaacgca ttaccaagga
    61741 gcaaatagag attctttggc aggtttatca aggtcagagg gagcaatatc ttgactaaga
    61801 agatgattat cgtattttta aatccatttt taacaactag catggtataa taatatgcag
    61861 gaaaattttg aattatgagg aagactagat gaatttatgg gatattttct ttacgactca
    61921 ggcaaccaag ccgcccaaat ttgacctttt ttggtatgtt agcctattta cgctcttagc
    61981 cttaaccttt tatacagccc atcgctatcg tgaaaagaag gtttaccaac gatttttcca
    62041 aatcttgcag actgttcagt taatccttct ttatggttgg tactgggtca atcatatgcc
    62101 actgtcagaa agcctaccct tttaccattg ccgtatggct atgtttgtgg tactcttgct
    62161 tcctggtcaa tccaaatata aacaatactt tgcattattg ggaacatttg ggacattagc
    62221 agcctttgtt tatccagtgc cagatgctta cccttttcca catatcacca ttctatcctt
    62281 tatctttggt catttagcac tcttggggaa ctctctagtt tatctattga gacagtataa
    62341 tgcgcgattg ctggatgtga agggaatttt tctcatgacc tttgccctaa atgccttgat
    62401 ttttgtggtc aatttggtga caggtggcga ttacggattt ttgacaaaac cgccattggt
    62461 tggggatcac ggtctagtag ctaattattt acttgtttca attgtgctgg tagctactat
    62521 cagtttgact aagaaaatct tagaattctt tttagctcaa gaagcagaaa aaatgattgt
    62581 aaaggaagct taacacagag ctttcttttt tgctcttaga gagtttttac aatcagctta
    62641 taaaataaga atttctgaat agacaaactc aaaaaatggc tgggaaattt aggaaaaaag
    62701 caagcacgat taaatttttt gtgttataat attttgtgaa tagctatgcc tatgtttagc
    62761 tatggaataa tacgaagtgc gaaacttgga agatagagag gaagcgatgt aatggctaga
    62821 gaaggctttt ttacaggtct agatattgga acaagctctg tcaaggtgct tgtggccgag
    62881 cagagaaatg gtgaattaaa tgtaattggc gtgagtaatg ccaaaagtaa aggtgtaaag
    62941 gatggaatta ttgttgatat tgatgcagca gcaactgcta tcaagtcagc catttcccaa
    63001 gcggaagaaa aggcaggcat ttcgattaaa tcagtaaatg tcggcttgcc tggtaatctt
    63061 ttgcaggtag aaccaactca ggggatgatt ccagtaacat ctgatactaa ggaaattacg
    63121 gatcaagatg ttgaaaatgt tgtcaaatca gctttgacaa agagtatgac acctgaccgt
    63181 gaagtcatta cctttattcc tgaagaattt attgtggatg gtttccaagg gattcgtgac
    63241 ccacgtggca tgatgggggt tcgccttgaa atgcgtggtt tgctttatac aggacctcgt
    63301 actatcttgc acaatttgcg taagacggtt gagcgtgcag gtgttcaggt tgaaaatgtt
    63361 atcatttcac cactagcaat ggttcagtct gttttgaacg aaggggaacg tgaatttggt
    63421 gctacagtga ttgatatggg ggcaggtcaa acgactgtcg ctacaatccg taatcaagaa
    63481 ctccagttca cacatattct ccaagaaggt ggagattatg taactaaaga tatctccaag
    63541 gttttgaaaa cctctcgcaa attagcggaa ggcttgaaac tgaattacgg ggaagcctat
    63601 ccgcctcttg caagcaaaga aaccttccaa gtagaggtta ttggagaagt agaagcagtc
    63661 gaagtgacgg aagcctactt gtcagaaatt atttctgcac gaatcaagca catccttgaa
    63721 caaatcaagc aagaattaga tagaaggcgt ctattggacc tccctggtgg tattgtctta
    63781 atcggtggga atgccatttt accaggtatg gttgagcttg ctcaggaagt ctttggcgtc
    63841 cgtgtcaagc tttatgttcc aaatcaagtt ggtatccgta atccagcctt tgcgcatgtg
    63901 attagtttat cagaatttgc gggtcaatta acagaagtta atcttttggc tcagggagcg
    63961 ataaaaggtg agaatgactt aagtcatcag ccaattagtt ttggtgggat gctgcaaaaa
    64021 acagctcagt ttgtacaatc aacgcctgtt caaccagctc ctgctccaga agtagagccg
    64081 gtggcgccta cagaaccaat ggcggatttc caacaagctt cacaaaataa accgaaatta
    64141 gcagatcgtt tccgtggctt gatcggaagc atgtttgacg aataaagagg aaaaataaat
    64201 tatgacattt tcatttgata cagctgctgc tcaaggggca gtgattaaag taattggtgt
    64261 cggtggaggt ggtggcaatg ccatcaaccg tatggtcgac gaaggtgtta caggcgtaga
    64321 atttatcgca gcaaacacag atgtacaagc attgagtagt acaaaagctg agactgttat
    64381 tcagttggga cctaaattga ctcgtggttt gggtgcagga ggtcaacctg aggttggtcg
    64441 taaagccgct gaagaaagcg aagaaacact gacggaagct attagtggtg ccgatatggt
    64501 cttcatcact gctggtatgg gaggaggctc tggaactgga gctgctcctg ttattgctcg
    64561 tattgccaaa gatttaggtg cgcttacagt tggtgttgta acacgtccct ttggttttga
    64621 aggaagtaag cgtggacaat ttgctgtaga aggaatcaat caacttcgtg agcatgtaga
    64681 cactctattg attatctcaa acaacaattt gcttgaaatt gttgataaga aaacaccgct
    64741 tttggaggct cttagcgaag cggataacgt tcttcgtcaa ggtgttcaag ggattaccga
    64801 tttgattacc aatccaggat tgattaacct tgactttgcc gatgtgaaaa cggtaatggc
    64861 aaacaaaggg aatgctctta tgggtattgg tatcggtagt ggagaagaac gtgtggtaga
    64921 agcggcacgt aaggcaatct attcaccact tcttgaaaca actattgacg gtgctgagga
    64981 tgttatcgtc aacgttactg gtggtcttga cttaaccttg attgaggcag aagaggcttc
    65041 acaaattgtg aaccaggcag caggtcaagg agtgaacatc tggctcggta cttcaattga
    65101 tgaaagtatg cgtgatgaaa ttcgtgtaac agttgttgca acgggtgttc gtcaagaccg
    65161 cgtagaaaag gttgtggctc cacaagctag atctgctact aactaccgtg agacagtgaa
    65221 accagctcat tcacatggct ttgatcgtca ttttgatatg gcagaaacag ctgaattgcc
    65281 aaaacaaaat ccacgtcgtt tggaaccaac tcaggcatct gcttttggtg attgggatct
    65341 tcgccgtgaa tcgattgttc gtacaacaga ttcagtcgtt tctccagtcg agcgctttga
    65401 agccccaatt tcacaagatg aagatgaatt ggatacacct ccatttttca aaaatcgtta
    65461 agtaaatgaa tgtaaaagaa aatacagaac ttgtttttcg agaagttgca gaggctagtc
    65521 tgagtgctca tcgagagagt ggttcggtct ctgtcattgc agttaccaag tatgtagatg
    65581 taccgacagc ggaagccttg cttccgctag gtgttcatca tatcggtgaa aatcgtgtag
    65641 ataagtttct ggaaaaatat gaagctttaa aagatcgaga tgtgacttgg catttgattg
    65701 gtaccttgca aagacgtaag gtgaaagatg tcattcaata cgttgattat ttccatgcat
    65761 tggactcagt aaagctagca ggggaaattc aaaaaagaag tgaccgagtc atcaagtgtt
    65821 tccttcaagt aaatatttct aaagaagaaa gcaaacacgg tttttcgaga gaggaactgc
    65881 tggaaatctt gccagagtta gccagactag ataagattga atatgttggt ttaatgacga
    65941 tggcaccttt tgaggctagc agtgagcagt tgaaagagat tttcaaggcg gcccaagatt
    66001 tacaaagaga aattcaagag aaacaaattc caaatatgcc tatgaccgag ttaagtatgg
    66061 gaatgagtcg tgattataaa gaagcgattc aattcggttc cacttttgtt cgtataggta
    66121 catcattttt taagtaggag agaaccatgt ctttaaaaga tagattcgat agatttatag
    66181 attattttac ggaggatgag gattcaagtc tcccttatga aaaaagagat gagcctgtgt
    66241 ttacttcagt aaattcttca caggaaccgg ctctcccaat gaatcaacct tcacagtcgg
    66301 ctggtacaaa agagaacaat atcaccagac ttcatgcaag acaacaggaa ttggcaaatc
    66361 agagtcagcg tgcaacggat aaggtcatta tagatgttcg ttatcctaga aaatatgagg
    66421 atgcaacaga aattgttgat ttattggcag gaaacgaaag tatcttgatt gactttcagt
    66481 atatgacaga ggtgcaggct cgtcgttgtt tggactattt ggatggagct tgtcatgttt
    66541 tagctggaaa tttgaaaaag gtagcttcta ccatgtattt gttgacacca gtgaacgtta
    66601 ttgtaaatgt tgaagatatc cgtttaccag atgaagatca acagggtgag ttcggttttg
    66661 atatgaagcg aaatagagta cgataatgat ttttttaatt cgtatgattt ataatgcagt
    66721 ggatatttac tccctgattt tggtagcctt cgctgtcatg tcttggtttc caggtgccta
    66781 cgaatccagt ttaggtcgtt ggattgtagc gttggtgaaa ccagtgcttg ctcccttgca
    66841 acgcctgcct ttacagatag cgggtcttga tttatctgtt tgggttgcga ttgttttggt
    66901 tcgattttta ggagaaaacc tagtgcgttt tctggcgatg ataggatgaa taaagggatt
    66961 tatcagcatt tctccataga agatcgtcca tttcttgaca agggaatgga atggataaag
    67021 aaggtagaag atagctatgc tcctttttta actcctttta tcaatcctca tcaggagaag
    67081 ctattaaaga ttttggccaa aacctatggt cttgcttgta gcagtagtgg ggaattcgtc
    67141 tcgagtgagt atgttcgagt tttattatac ccagattatt tccaaccaga gttttcagat
    67201 tttgaaatat ctctccagga aattgtgtat tccaataaat ttgaacattt aacgcatgct
    67261 aagattttag ggacagtcat caatcaatta gggattgaac ggaaactttt tggagatatc
    67321 ctagtagatg aagaacgggc gcagattatg attaatcagc agtttcttct tctctttcaa
    67381 gatggactaa agaaaattgg tcgtatacct gtttcgctgg aggaacgtcc tttcaccgag
    67441 aaaatagata agctagaaca gtatcgagaa ctggatttat ctgtgtctag ttttcgatta
    67501 gatgttcttt tatcaaatgt tttgaaacta tctaggaatc aagcaaacca gttgattgaa
    67561 aagaaacttg tccaagtaaa ttatcatgtg gtagacaaat cagattacac tgttcaagtt
    67621 ggagacttga ttagtgtgag aaaatttggt cgcttgagat tacttcaaga taagggacaa
    67681 acgaaaaaag agaagaaaaa aataaccgtc cagttattat taagtaagtg aggaatagaa
    67741 tgccaattac atcattagaa ataaaggaca agacttttgg aactcgattc agaggttttg
    67801 atccagaaga agtcgatgaa tttttagata ttgtggttcg tgattacgaa gatcttgtgc
    67861 gtgcgaatca tgataaaaat ttgcgtatta agagtttaga agagcgtttg tcttactttg
    67921 atgaaataaa agattcattg agccagtctg tattgattgc tcaggataca gctgagagag
    67981 tgaaacaggc ggcgcatgaa cgttcaaaca atatcattca tcaagcagag caagatgcgc
    68041 aacgcttgtt ggaagaagct aaatataagg caaacgagat tcttcgtcaa gcaactgata
    68101 atgctaagaa agtcgctgtt gaaacagaag aattgaagaa caagagccgt gtcttccacc
    68161 aacgtctcaa atctacaatt gagagtcagt tggctattgt tgaatcttca gattgggaag
    68221 atattctccg tccaacagct acttatcttc aaaccagtga tgaagccttt aaagaagtgg
    68281 ttagcgaagt acttggagaa ccgattccag ctccaattga agaagaacca attgatatga
    68341 cacgtcagtt ctctcaagca gaaatggcag aattacaagc tcgtattgag gtagccgata
    68401 aagaattgtc tgaatttgaa gctcagatta aacaggaagt ggaaactcca actcctgtag
    68461 tgagtcctca agttgaagaa gagcctctgc tcatccagtt ggcccaatgt atgaagaacc
    68521 agaagtagct ccagtgcatc cgacaggtcc aacaccagct acagaaactg ttgattcagc
    68581 accgggattt gaagcaccgc aagaatctgt tacaatttta taagaaatat tctgagaaca
    68641 atatcttatc cttatattcc cagcgagcag gagatggtgt gagtcctgca ttccctatcg
    68701 ataagattat cctctcaaac tatcaagtct gaatctagta agatttgacg ttccccacgt
    68761 tacgggataa gagggagaaa gactaaaact ttttccgaat aaaggtggta ccacgatttt
    68821 cgtccttttt ggaagtcgtg gtttttaatt tgttattatt tataaaggag ataccatgaa
    68881 actcaaagac acccttaatc ttgggaaaac tgaattccca atgcgtgcag gccttcctac
    68941 caaagagcca gtttggcaaa aggaatggga agatgcaaaa ctttatcaac gtcgtcaaga
    69001 attgaaccaa ggaaaacctc atttcacctt gcatgatggc cctccatacg ctaacggaaa
    69061 tatccacgtt ggacatgcta tgaacaagat ttcaaaagat attattgttc gttctaagtc
    69121 tatgtcagga ttttacgcac catttattcc tggttgggat actcatggtc tgccaatcga
    69181 gcaagtattg tcaaaacaag gtgtcaaacg taaagaaatg gacttggttg agtacttgaa
    69241 actttgccgt gagtacgctc tttctcaagt agataaacaa cgtgaagatt ttaaacgttt
    69301 gggtgtttct ggtgactggg aaaatccata tgtgaccttg actcctgact atgaagcagc
    69361 tcaaattcgt gtatttggtg agatggctaa taagggttat atctaccgtg gtgccaagcc
    69421 agtttactgg tcatggtcat ctgagtcagc ccttgctgaa gcagagattg aataccatga
    69481 cttggtttca acttcccttt actatgccaa caaggtaaaa gatggcaaag gagttctaga
    69541 tacagatact tatatcgttg tctggacaac gactccattt accatcacag cttctcgtgg
    69601 tttgacggtt ggtgcagata ttgattacgt tttggttcaa cctgttggtg aagctcgtaa
    69661 gtttgtcgtt gctgctgaat tattgactag cttgtctgag aaatttggct gggctgatgt
    69721 tcaagttttg gaaacttacc gtggccaaga actcaaccac atcgtaacag aacacccatg
    69781 ggatacagct gtagaagagt tggtaattct tggtgaccac gttacgactg actctggtac
    69841 aggtattgtc catacagccc ctggttttgg tgaggacgat tacaatgttg gtattgctaa
    69901 taatcttgaa gtcgcagtga ctgttgatga acgtggtatc atgatgaaga atgctggtcc
    69961 tgaatttgaa ggtcaattct atgaaaaggt agttccaact gttattgaaa aacttggtaa
    70021 cctccttctt gcccaagaag aaatctctca ctcatatcca tttgactggc gtactaagaa
    70081 accaatcatc tggcgtgcag ttccacaatg gtttgcctca gtttctaaat tccgtcaaga
    70141 aatcttggac gaaattgaaa aagtgaaatt ccactcagaa tggggtaaag tccgtcttta
    70201 caatatgatc cgtgatcgtg gtgactgggt tatctctcgt caacgtactt ggggtgttcc
    70261 acttcctatc ttctacgctg aagatggtac agctatcatg gtagctgaaa ctattgaaca
    70321 cgtagctcaa ctttttgaaa aacatggttc aagcatttgg tgggaacgtg atgccaaaga
    70381 cctcttgcca gaaggattta ctcatccagg ttcaccaaac ggcgagttca aaaaagaaac
    70441 tgatatcatg gacgtttggt ttgactcagg ttcatcatgg aatggagtgg tggtaaaccg
    70501 tcctgaattg acttacccag ccgaccttta cctagaaggt tctgaccaat accgtggttg
    70561 gtttaactca tcacttatca catctgttgc caaccatggc gtagcacctt acaaacaaat
    70621 cttgtcacaa ggttttgccc ttgatggtaa aggtgagaag atgtctaaat ctcttggaaa
    70681 tactattgct ccaagcgatg ttgaaaaaca attcggtgct gaaatcttgc gtctctgggt
    70741 aacaagtgtt gactcaagca atgacgtgcg tatctctatg gatatcttga gccaagtttc
    70801 tgaaacttac cgtaagattc gtaacactct tcgtttcttg attgccaata catctgactt
    70861 taacccagct caagatacag tcgcttacga tgagcttcgt tcagttgata agtacatgac
    70921 gattcgcttt aaccagcttg tcaagaccat tcgtgatgcc tatgcagact ttgaattctt
    70981 gacgatctac aaggccttgg tgaactttat caacgttgac ttgtcagcct tctaccttga
    71041 ttttgccaaa gatgttgttt acattgaagg tgccaaatca ctggaacgcc gtcaaatgca
    71101 gactgtcttc tatgacattc ttgtcaaaat caccaaactc ttgacaccaa tccttcctca
    71161 cactgcggaa gaaatttggt catatcttga gtttgaaaca gaagacttcg tccaattgtc
    71221 agaattacca gaagttcaaa cttttgctaa ccaagaagaa atcttggata catgggcagc
    71281 cttcatggac tttcgtggac aagcacaaaa agccttggaa gaagctcgta atgcaaaagt
    71341 tatcggtaaa tcacttgaag cacacttgac agtttatcca aatgaagttg tgaaaactct
    71401 actcgaagca gtaaacagca atgtagctca acttttgatc gtgtctgagt tgaccatcgc
    71461 agaagaacca gctccggaag ctgcccttag cttcgaagat gtagccttca cagttgaacg
    71521 tgctgctggt gaagtatgtg accgttgccg tcgtatcgac ccaacaacag cagaacgcag
    71581 ctaccaggca gttatctgtg accactgtgc aagcatcgta gaagaaaatt ttgcggatgc
    71641 agtcgcagaa ggatttgaag agaaataaga ttgaaaagtc taggcaaaat tcaatttgag
    71701 aagaaaagac aactaatttt atggtctatt aaacgcattg tatcacgttt ttgaacacct
    71761 gatatgatgc gtttttattt attttgaaaa tttgtgaggt gtgacttttt atactcaaca
    71821 agaatcaaag agaaacttag caagctaaca gtagtaagat aaaataggaa tttgatat
//
LOCUS       DAVHSH010000005        67684 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000005 DAVHSH010000000
VERSION     DAVHSH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.005"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            42..449
                     /locus_tag="VVR08_000411"
     CDS             42..449
                     /locus_tag="VVR08_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU6074380.1"
                     /translation="MWKVAQRELVTGFYYGTPSENEQLFGARCKIPEYKFVAEVVSYD
                     DATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIK
                     VPQLVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            912..1677
                     /locus_tag="VVR08_000412"
                     /pseudo
     CDS             912..1677
                     /locus_tag="VVR08_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            1693..2421
                     /locus_tag="VVR08_000413"
     CDS             1693..2421
                     /locus_tag="VVR08_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074381.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPLFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            2806..3015
                     /locus_tag="VVR08_000414"
     CDS             2806..3015
                     /locus_tag="VVR08_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6074382.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            3005..3493
                     /locus_tag="VVR08_000415"
     CDS             3005..3493
                     /locus_tag="VVR08_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074383.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESLYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            3609..5069
                     /locus_tag="VVR08_000416"
     CDS             3609..5069
                     /locus_tag="VVR08_000416"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU6074384.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEGLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            5066..5890
                     /gene="nadE"
                     /locus_tag="VVR08_000417"
     CDS             5066..5890
                     /gene="nadE"
                     /locus_tag="VVR08_000417"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU6074385.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGFHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            6240..6791
                     /locus_tag="VVR08_000418"
     CDS             6240..6791
                     /locus_tag="VVR08_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074386.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            7506..8198
                     /locus_tag="VVR08_000419"
     CDS             7506..8198
                     /locus_tag="VVR08_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6074387.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
     gene            8252..8641
                     /locus_tag="VVR08_000420"
     CDS             8252..8641
                     /locus_tag="VVR08_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6074388.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNIDGSMATGWVQVNDSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(9302..10330)
                     /gene="queA"
                     /locus_tag="VVR08_000421"
     CDS             complement(9302..10330)
                     /gene="queA"
                     /locus_tag="VVR08_000421"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU6074389.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            10481..11188
                     /locus_tag="VVR08_000422"
     CDS             10481..11188
                     /locus_tag="VVR08_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU6074390.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            11328..11504
                     /locus_tag="VVR08_000423"
     CDS             11328..11504
                     /locus_tag="VVR08_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU6074391.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            11634..12569
                     /locus_tag="VVR08_000424"
     CDS             11634..12569
                     /locus_tag="VVR08_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU6074392.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            12562..13350
                     /locus_tag="VVR08_000425"
     CDS             12562..13350
                     /locus_tag="VVR08_000425"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU6074393.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            13351..13734
                     /locus_tag="VVR08_000426"
     CDS             13351..13734
                     /locus_tag="VVR08_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU6074394.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            13750..14139
                     /locus_tag="VVR08_000427"
     CDS             13750..14139
                     /locus_tag="VVR08_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6074395.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            14223..15353
                     /locus_tag="VVR08_000428"
     CDS             14223..15353
                     /locus_tag="VVR08_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU6074396.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERASFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            15358..16095
                     /locus_tag="VVR08_000429"
     CDS             15358..16095
                     /locus_tag="VVR08_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU6074397.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELEV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            16106..16879
                     /locus_tag="VVR08_000430"
     CDS             16106..16879
                     /locus_tag="VVR08_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU6074398.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            16869..17486
                     /locus_tag="VVR08_000431"
     CDS             16869..17486
                     /locus_tag="VVR08_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU6074399.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            17696..18097
                     /locus_tag="VVR08_000432"
     CDS             17696..18097
                     /locus_tag="VVR08_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU6074400.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            18097..18375
                     /locus_tag="VVR08_000433"
     CDS             18097..18375
                     /locus_tag="VVR08_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU6074401.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            18365..19138
                     /locus_tag="VVR08_000434"
     CDS             18365..19138
                     /locus_tag="VVR08_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU6074402.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            19139..20443
                     /locus_tag="VVR08_000435"
     CDS             19139..20443
                     /locus_tag="VVR08_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU6074403.1"
                     /translation="MQFPEGFVEKYKEILGDEARNFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            21017..21895
                     /gene="pstS"
                     /locus_tag="VVR08_000436"
     CDS             21017..21895
                     /gene="pstS"
                     /locus_tag="VVR08_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU6074404.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            21895..22812
                     /gene="pstC"
                     /locus_tag="VVR08_000437"
     CDS             21895..22812
                     /gene="pstC"
                     /locus_tag="VVR08_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6074405.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            22802..23686
                     /gene="pstA"
                     /locus_tag="VVR08_000438"
     CDS             22802..23686
                     /gene="pstA"
                     /locus_tag="VVR08_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6074406.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            23697..24500
                     /gene="pstB"
                     /locus_tag="VVR08_000439"
     CDS             23697..24500
                     /gene="pstB"
                     /locus_tag="VVR08_000439"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6074407.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            24513..25271
                     /gene="pstB"
                     /locus_tag="VVR08_000440"
     CDS             24513..25271
                     /gene="pstB"
                     /locus_tag="VVR08_000440"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6074408.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            25283..25936
                     /gene="phoU"
                     /locus_tag="VVR08_000441"
     CDS             25283..25936
                     /gene="phoU"
                     /locus_tag="VVR08_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6074409.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            26093..26908
                     /locus_tag="VVR08_000442"
     CDS             26093..26908
                     /locus_tag="VVR08_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6074410.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(26928..28199)
                     /locus_tag="VVR08_000443"
     CDS             complement(26928..28199)
                     /locus_tag="VVR08_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU6074411.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            28341..29072
                     /gene="budA"
                     /locus_tag="VVR08_000444"
     CDS             28341..29072
                     /gene="budA"
                     /locus_tag="VVR08_000444"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU6074412.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            29082..29273
                     /locus_tag="VVR08_000445"
     CDS             29082..29273
                     /locus_tag="VVR08_000445"
                     /inference="COORDINATES: protein motif:HMM:NF021592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU6074413.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKRR"
     gene            29308..29835
                     /locus_tag="VVR08_000446"
     CDS             29308..29835
                     /locus_tag="VVR08_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU6074414.1"
                     /translation="MIYGLAMAAFFEETARLVFFKWLEKKRSLEKADALAYGLGHGGL
                     ELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQSLSVWQIYLLGFERILAL
                     GFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQVGWLTNPVLVEVILALEL
                     VLVAYGTKEIFCKKS"
     gene            29947..30897
                     /gene="murB"
                     /locus_tag="VVR08_000447"
     CDS             29947..30897
                     /gene="murB"
                     /locus_tag="VVR08_000447"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU6074415.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            30955..32112
                     /locus_tag="VVR08_000448"
     CDS             30955..32112
                     /locus_tag="VVR08_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074416.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            32093..32899
                     /locus_tag="VVR08_000449"
     CDS             32093..32899
                     /locus_tag="VVR08_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074417.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            32896..33669
                     /locus_tag="VVR08_000450"
     CDS             32896..33669
                     /locus_tag="VVR08_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074418.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            33666..34736
                     /locus_tag="VVR08_000451"
     CDS             33666..34736
                     /locus_tag="VVR08_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6074419.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            35005..35244
                     /locus_tag="VVR08_000452"
     CDS             35005..35244
                     /locus_tag="VVR08_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074420.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            35519..36004
                     /locus_tag="VVR08_000453"
     CDS             35519..36004
                     /locus_tag="VVR08_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU6074421.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     Y"
     gene            36026..38644
                     /gene="alaS"
                     /locus_tag="VVR08_000454"
     CDS             36026..38644
                     /gene="alaS"
                     /locus_tag="VVR08_000454"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU6074422.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GNIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQLSVSDAGALRTFADNWK
                     QKDYSDFLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGR
                     NQAKIQELLDAVAGKL"
     gene            complement(38734..40188)
                     /locus_tag="VVR08_000455"
     CDS             complement(38734..40188)
                     /locus_tag="VVR08_000455"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU6074423.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFIDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            40367..41116
                     /locus_tag="VVR08_000456"
     CDS             40367..41116
                     /locus_tag="VVR08_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074424.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCNRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            41097..42731
                     /locus_tag="VVR08_000457"
     CDS             41097..42731
                     /locus_tag="VVR08_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074425.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYRSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEDKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            43415..44578
                     /locus_tag="VVR08_000458"
     CDS             43415..44578
                     /locus_tag="VVR08_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU6074426.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGNYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLTMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            44575..45252
                     /locus_tag="VVR08_000459"
     CDS             44575..45252
                     /locus_tag="VVR08_000459"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU6074427.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            45242..46096
                     /locus_tag="VVR08_000460"
     CDS             45242..46096
                     /locus_tag="VVR08_000460"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU6074428.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            46115..47182
                     /locus_tag="VVR08_000461"
     CDS             46115..47182
                     /locus_tag="VVR08_000461"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU6074429.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            47192..48358
                     /gene="aroC"
                     /locus_tag="VVR08_000462"
     CDS             47192..48358
                     /gene="aroC"
                     /locus_tag="VVR08_000462"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU6074430.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            48368..49471
                     /locus_tag="VVR08_000463"
     CDS             48368..49471
                     /locus_tag="VVR08_000463"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU6074431.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            49482..49820
                     /locus_tag="VVR08_000464"
     CDS             49482..49820
                     /locus_tag="VVR08_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU6074432.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            49912..51195
                     /gene="aroA"
                     /locus_tag="VVR08_000465"
     CDS             49912..51195
                     /gene="aroA"
                     /locus_tag="VVR08_000465"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU6074433.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            51188..51664
                     /locus_tag="VVR08_000466"
     CDS             51188..51664
                     /locus_tag="VVR08_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU6074434.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            51661..52509
                     /gene="pheA"
                     /locus_tag="VVR08_000467"
     CDS             51661..52509
                     /gene="pheA"
                     /locus_tag="VVR08_000467"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6074435.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            52506..53780
                     /gene="psr"
                     /locus_tag="VVR08_000468"
     CDS             52506..53780
                     /gene="psr"
                     /locus_tag="VVR08_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU6074436.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            54059..54904
                     /locus_tag="VVR08_000469"
     CDS             54059..54904
                     /locus_tag="VVR08_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6074437.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFFPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            54894..55997
                     /locus_tag="VVR08_000470"
     CDS             54894..55997
                     /locus_tag="VVR08_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6074438.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            55999..56985
                     /locus_tag="VVR08_000471"
     CDS             55999..56985
                     /locus_tag="VVR08_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6074439.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDARVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            57001..58434
                     /locus_tag="VVR08_000472"
     CDS             57001..58434
                     /locus_tag="VVR08_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU6074440.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            58463..59497
                     /locus_tag="VVR08_000473"
     CDS             58463..59497
                     /locus_tag="VVR08_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6074441.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            59697..60434
                     /gene="mecA"
                     /locus_tag="VVR08_000474"
     CDS             59697..60434
                     /gene="mecA"
                     /locus_tag="VVR08_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU6074442.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            60585..61871
                     /locus_tag="VVR08_000475"
     CDS             60585..61871
                     /locus_tag="VVR08_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU6074443.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDVTIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            61873..62742
                     /locus_tag="VVR08_000476"
     CDS             61873..62742
                     /locus_tag="VVR08_000476"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU6074444.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            62812..62892
                     /locus_tag="VVR08_000477"
                     /pseudo
     CDS             62812..62892
                     /locus_tag="VVR08_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            63037..63975
                     /gene="msrB"
                     /locus_tag="VVR08_000478"
     CDS             63037..63975
                     /gene="msrB"
                     /locus_tag="VVR08_000478"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6074445.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            64033..65757
                     /locus_tag="VVR08_000479"
     CDS             64033..65757
                     /locus_tag="VVR08_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074446.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGTRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLITSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            65759..67507
                     /locus_tag="VVR08_000480"
     CDS             65759..67507
                     /locus_tag="VVR08_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074447.1"
                     /translation="MKRQTVNQTLKRLVVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
BASE COUNT        19688 a        12580 c        15246 g        20170 t
ORIGIN      
        1 ctgaaaagtt tgaagctatc aaacaagact tggtggacga gatgtggaag gttgcccaac
       61 gtgaactggt tacaggattt tactatggta caccatctga aaatgagcag ttgtttggtg
      121 ctcgttgtaa aattcctgag tacaagtttg tcgctgaagt ggtttcttat gatgatgcga
      181 cacaaacagc aaccattcgt caacggaacg tcattaacga aggggaccaa gttgagtttt
      241 atggtccagg tttccgtcat tttgaaacct atattgaaga tttgcatgat gccaaaggca
      301 ataaaatcga ccgcgctcca aatccaatgg aactattgac tattaaagtc ccacaacttg
      361 ttcaagctgg agacatggtt cgagctctta aagaggggct tatcaatctt tataaggaag
      421 atggaaccag cgtcacagtt cgtgcttaat gtagttgttt agttttaaaa aattatgcaa
      481 agctccatat acaacactta aacgagatta aagaatggcg aaatcccttg atgcgcaaga
      541 gattagctgt ccttttttat tttttaagtg ataaagtcgg agcttaggta ttaaagccta
      601 tcaaattaaa caaagaagcg atgtcttaga tattttgaaa aaaattaata agcagaaaac
      661 tctctattat tttgttgtag agagtttttt gttaataaaa ttttacaaaa tgacatttat
      721 atattgcatt aagttagata tatgatataa tattgttaaa aagaggcgca actttttaaa
      781 ctcaataaga atcaaagagc aaaccatgaa tattaatgga ggaataaaaa atgtaagtta
      841 taaatgtaag taagcattat ggtcattcaa tcattctcaa agatataaat tttgcactta
      901 acaagggtga aattgttggt ctagtaggga gaaatggagt tggtaagagt acgttgatga
      961 aaattcttgt tcaaaataat caaccgactt caggtaatat tataagcagt gataatgttg
     1021 ggtatttaat cgaagaacca aaattatttt tatctaaaac aggtttagag aatttaaaat
     1081 atttgtcaaa tttatatggt gttgactaca atcaagaaag atttagaagt ttgatccaag
     1141 agttagattt gactcagtct attaataaaa aagtaaagac ctattctttg ggtacaaaac
     1201 aaaaattagc tttgcttcta actctcgtta cggaacctga tatattgatt ttagatgaac
     1261 cgactaatgg tttagatatt gaatcatcac aaatagtttt agcggttcta aaaaaaatta
     1321 gctttaaatg aaaacgtggg aattttaata tcgagtcata aattagaaga cattgaagaa
     1381 atttgtgaga gagttctttt cttggagaac gggcttttga catttcaaaa agtaggaaaa
     1441 gatagtcata atttcttgtt tgagatagct ttttcatcag ctacagatag agacattttc
     1501 attaccaaac aagaatttgg agatattgtt caggaagagg gactgagaat tactatgtct
     1561 gggaatattc aaagtagtga gctttttaaa ttttttaacg aaaactctat taaagtagtt
     1621 gattttgaaa ctaaaaaaga gacgcttaaa gatatttacc taaatcgttc aaaataaagg
     1681 aaggttataa tcatgaaatt aaataaattg aattttctta aggaaaatat aagaaattta
     1741 tattcatcag gcgtaatata tctcagtttg cttatctcgt ttataccgcc gatattgctt
     1801 acattcttta ttctaaagac tcaagggaca tcgcttggta ttaagcatat ttcaaacttt
     1861 tatgctatgc tcggtatgtt aatggctgtt atacatgcta atcgagtcat tagtagagat
     1921 ttttcccaca atacggtaag tttgttttat aatcaacaga agaatcggat gatttacgtc
     1981 ttgtctaatt ttctatatgc catctcagtt tccattattt atgctttgaa tggcattgtg
     2041 ttactagtca tagtaagtaa attgggtatt ccaggtgatt taggattaga ttttatagta
     2101 gctattgtag tcaatacaat tttgttagtc ctgttttatt ttctattatc ctacattttc
     2161 tatttataca aattgaaaag tggcttggta tttggtattt tagtagcttt actactcttt
     2221 atccctaata tattaaatac gatgatgatg aatactagta atgatttgtt tatcaaagca
     2281 attgaacttc ttccttttta ttctttacct ctatttgtgg cttcaaatac gatgtctatt
     2341 agtcagtatc ttgtgctaat cactacaatc attttattgt actttttcac tctcaagaaa
     2401 agcaagaagt attcatttta gtttcattta gtattatttt gcatacctaa aatacagtaa
     2461 aaaatcagtc atcttggtat gctcctgctt tcactattca acacgttttt gacttatact
     2521 aggctcattt ccaaaagcat tatataatag tgatatgaaa ccaactaaac taaacaagaa
     2581 atataagcaa taaaaactcg tttaaaagat cctactaaag ctaatactaa ataaaaataa
     2641 aagagtaaac taggaagttt atttcaaaca acctaaaata ctgattttcg gctgaagata
     2701 atactggagt gcaaattaat ggggttataa taaatagctg atagcttgtg ttggttttgg
     2761 attttttaag agtagatgag tattaaaact ataaggagga cgaaggtggc taaaaattta
     2821 aaattaaaat tagctcgggt agagcgtgat ttaacacaag gtcaactggc agaggctgtc
     2881 ggggtgacac gccagactat tggtttgata gaggcgggaa aatacaatcc cagtctctcg
     2941 ctctgccagt ctatttgcag atgtttaggg aaaaccctag accaactatt ttgggaggaa
     3001 gaagatgaaa aatagatttt attattatca attactagac gaaagagaag aacaactgtt
     3061 caataaagcg ggctctgaaa gtctctatat ctgcatcgct ttgtcgctcc tatcttatat
     3121 catttcagta ttagcaccaa gcctttttaa ttctaatatg ctgctaatcg ttatcatcat
     3181 agggacattt tactttttca atcgtgcccg ttatctggga gtgacctact atagtcgttt
     3241 tcattttacg attttgggtt gttttttcct aaccttggct attacggctc ttttgatgtt
     3301 gcagaattat caattcaaca tagaaattta tcagcacaat cctttgaatt ttaaatacct
     3361 gtctgcttgg gtcattactt atgtcattta ccttccgtgg gtctttattg gcaatcttgg
     3421 tcttaagagc tatggcgaat gggctcagaa aaaatttgaa caagatatgg atgaattgga
     3481 gagtggagaa tagcttgtta ctcttttctc aatccagcta aaatgtgata taatagtact
     3541 aatttattgg aatacatgaa agttcttgaa aattttcatg ggtttctagc taaggaagta
     3601 ggaaaagtat gtatccagat gatagtttga cattgcacac ggacttgtac cagatcaaca
     3661 tgatgcaggt ttactttgac caagggattc acaataagaa ggcggtcttt gaggtgtatt
     3721 tccgccaaca gccttttaag aacggctatg cggtttttgc aggtttggaa agaattgtga
     3781 actatcttga aggcttgcgt ttttcagata gtgatatagc ctatttggag tcgcttggtt
     3841 atcatggggc gttcttggat taccttcgca atttcaagtt ggagttgacc gttcgttctg
     3901 cccaagaagg ggatttggtt tttgctaatg aaccgattgt gcaggtggaa ggacctctag
     3961 cccaatgtca gttggtcgaa acggctcttt tgaacatcgt caactaccag accttggtgg
     4021 cgacgaaggc agctcgtatt cgttcggtta tcgaagatga acccttgatg gagtttggga
     4081 cacgtcgggc tcaagaaatg gatgcggcca tctggggaac acgcgcagcg gtgattggtg
     4141 gcgccaatgg aaccagcaac gtgcgtgcgg gtaagctctt tgacattcct gttttgggaa
     4201 cccatgccca tgccttggta caggtttatg gcaatgacta tgaggctttc aaggcttacg
     4261 ctgcgaccca caaaaattgt gtctttcttg tggataccta tgataccctt cgcatcggtg
     4321 taccagctgc cattcaggtg gcgcgtgagc tgggtgatca gattaacttt atgggtgtgc
     4381 ggattgactc tggggatatt gcctacattt ctaagaaagt ccgtcagcaa ctggacgagg
     4441 ctggatttac agaggctaag atttatgctt ctaatgatct agatgaaaat accatcctta
     4501 acctcaagat gcaaaaggcc aagattgatg tctggggtgt gggtaccaag ctgattacag
     4561 cctatgacca gccggctctt ggggcggttt acaagattgt tgcaatcgaa gatgaaaacg
     4621 gccagatgcg caatacgatt aagctgtcta ataatgcgga aaaagtgtcg acgccaggta
     4681 agaagcaggt gtggcgcatt accagtcgtg aaaaaggcaa gtcagaaggt gactacatca
     4741 cttatgatgg tgtggatatt agcgacatga cagaaatcaa gatgttccat ccgacctata
     4801 catacatcaa gaagacggtt cgtaattttg atgctgttcc tctcttggtg gatatcttca
     4861 aagaaggaat attagtttac aacttgccta gtttgactga cattcaggat tatgcccgta
     4921 aggaatttga caagttgtgg gatgagtata agcgtgtgct caatccgcag cactatccag
     4981 tggatttggc gcgtgacgta tggcaagata agatggactt gattgataag atgcgcaagg
     5041 aagcccttgg tgaaggagaa gaagaatgag tttgcaagaa acgattatcc aagagctggg
     5101 tgtcaaacca gtgattgatg cccaggaaga aatccgtcgt tctattgatt tcttaaaaag
     5161 atatctgaaa aaacatccct tcctaaaaac ctttgtacta gggatttctg ggggacaaga
     5221 ctcaaccttg gcaggacgtt tggcgcaatt agctatggaa gaactgcgag ctgaaacggg
     5281 agacgatagc tacaaattta tcgctgtccg cctgccatac ggagtgcaag ctgatgaagc
     5341 agatgctcaa aaagccctag ccttcatcca gccagatgtc agcttggttg tgaatatcaa
     5401 ggaatcagct gatgccatga cagctgcagt tgaagcgaca ggtagtcctg tttcagactt
     5461 caacaagggg aatatcaagg cacgttgccg tatgattgct cagtatgccc ttgctggttt
     5521 ccatagcgga gcggtcattg gaacagacca cgccgcagaa aatatcacag gtttctttac
     5581 caagtttggt gacggcggtg cggatattct ccctctttac cgcctcaata aacgccaagg
     5641 aaaacagctc ttgcagaaac ttggcgcaga gccagccctt tatgaaaaaa tcccaacggc
     5701 agacctagaa gaagataaac caggcctagc tgacgaagtc gcacttggag tcacctacgc
     5761 agagattgac gactacctag aaggcaaaac aatcagccca gaagctcaag cgaccattga
     5821 aaactggtgg cacaaaggcc aacacaaacg ccacttaccc atcactgtat ttgatgactt
     5881 ttgggagtaa aaaggtccgg gggacctttt tagcttcttg ccctgaaatt aaaaagcaag
     5941 aaaaacctcc agtggaggtt ttcagcctct catcttgaaa taagaaagtg agagaaggtc
     6001 tgggggatct tgaaccccga gtttagaaat aagaaaatga ggcagattcg gtaactcgaa
     6061 gagttcgatt tcatcgtctt acccctgcaa cgatgactag gtttgaaaaa gcttgctaga
     6121 gcgcatttca aaccaggcag cgactgcgtc aagaaattag aagacaaact cgttttctag
     6181 ctgttactga gttgagcctt tttactacga gcatagaaat aaggaagtga ggtagcatca
     6241 tgaaatctat cggtacgcaa atattacaga cagaacgttt gattttaaga agatttgtgg
     6301 agagtgatgc agaagccatg tttcaaaatt gggcttcatc cgctgagaat ctgacctatg
     6361 ttacctggga tccccatcct gatgtcgaaa tcactcgaaa ctcgattcgc aattgggttg
     6421 cttcctatac taatctcaac tattacaaat gggccatttg tctaaaagaa aacccagagc
     6481 aagtgatagg agatatcagc atcgttaaga tagacgaggc tgatttaagc tgtgaaatcg
     6541 gctatgtgct aggcaaggct tactggggac atggtatgat gacagaggcc ttgaaagctg
     6601 tcttggactt ttgttttact caagcaggtt ttcaaaaggt cagagcacgt tatgccagtc
     6661 tcaacccagc ttcaggtcgt gtcatggaaa aggctggaat gtcctatcta caaaccattg
     6721 ttaatggtgt agagagaaaa ggctatcttg cggatcttat ttattatggt ataagtaggg
     6781 aagaatgttg aattctattt tctgtttcta tcgaagtcaa ctatttattg taaatataat
     6841 aattagcatt ccaagtttat ttgaaacttt aaaatagcat attgattagt acaagacaga
     6901 tgttctagtt ccttctttaa tctggtttag tattagttaa aaaatcgctt taagcttgta
     6961 actaagaggg agctaatcga ctagattctc cagccgaaca ggtggtaatg tactttttat
     7021 agtgtaatcc tagctgttgt taaatttaaa atagaatcct ctatcgagtt agggaattaa
     7081 attcaaccaa ttttattcat gttttttcta tcaaattatc taatattaaa atagtctcat
     7141 tctgatgaga aaactattct atttatactg catagttgta taaggaatga tgaaagatga
     7201 gtgaaaatta tcaagttgga atgtttgtat ctaaatatat tagcatgtat ttagataaga
     7261 tgtctgcaat cctttatata tgagattgat tacgatatag ttaaagtgtt agttcaataa
     7321 tcaatatatc attctaagtc tattttatat ataaagtata ttgtttaacg tttgatagaa
     7381 aagatgctat actagaagta ggatgtaatg gcaaaatcta atactaataa gcgctatgca
     7441 ttacgtaaac tcggaaagat ttttggttct gcggtaaccg ggctaacttt atttttagga
     7501 ggaatctgaa tacaagtttt gttcatgctg ctgatgggat tcaatatgtc agagatgata
     7561 ctagagataa agaagaggga atagagtatg atgacgctga caatggggat attattgtaa
     7621 aagtagcgac taaacctaag gtagtaacca agaaaatttc aagtacgcga attcgttatg
     7681 aaaaagatga aacaaaagac cgtagtgaaa atcctgttac aattgatgga gaggatggct
     7741 atgtaactac gacaaggacc tacgatgtta atccagagac tggtcatgtt accgaacagg
     7801 ttactgttga tagaaaagaa gccacggata cagttatcaa agttccagct aaaagcaagg
     7861 ttgaagaagt tcttgttcca tttgctacta aatatgaagc agacaatgac ctttctgcag
     7921 gacaggagca agagattact ctaggaaaga atgggaaaac agttacaacg ataacttatg
     7981 atgtagatgg aaagagtgga caagtaactg agagtacttt aagtcaaaaa gaagactctc
     8041 aaacaagagt tgttaaaaaa ggaaccaagc cccaagttct tgtccaagaa attccaatcg
     8101 aaacagaata tctcgatggc ccaactcttg ataaaagtca agaagtagaa gaagtaggag
     8161 aaattggtaa attactctta ctacaatcta tactgtagat gaacgtgatg gaacaattga
     8221 agaaactact tctcgtcaaa ttactaaaga gatggtaaaa agacgtataa ggagagggac
     8281 gagagaacct gaaaaagttg ttgttcctga gcaatcatct attccttcgt atcctgtatc
     8341 tgttacatct aaccaaggaa cagatgtagc agtagaacca gctaaagcag ttgctccaac
     8401 aacaggctgg aaacaagaaa atggtatgtg gtatttttat aatattgatg gttccatggc
     8461 aacaggttgg gtacaagtta atgattcatg gtactacctc aacagcaacg gttctatgaa
     8521 agtcaatcaa tggttccaag ttggtggtaa atggtattat gtaaatacat cgggtgagtt
     8581 agcggtcaat acaagtatag atggctatag agtcaatgat aatggtgaat gggtgcgtta
     8641 acagattcct ccctgcgaca aaattgataa tagtatgtct gaatatataa ttatatataa
     8701 aaagctatag ataaggtcat cttatagcga ctataaaaaa gtgaacaagc ctagtcttct
     8761 gtacattaga attcagattt gttcactttt tgtttaatac tcaatgaaaa tcaaagagca
     8821 aactagaaaa ctagtcgcag gttgctcaaa gtactgcttt gaggttgtag atagaactga
     8881 cgaagtcagt cacatatata atccaaggtg acgttgacgc ggtttgaaga gatttttgaa
     8941 gagtataagt ctttgatttt gagactaagg agagtcaggg tcaaagtagt gaatgattct
     9001 gaaataactc ataatagtct cttgagagga cagataagag taacaaatat ggtgctactc
     9061 atgtgtcttg cattttgatt tacaaacagc gaagaaaata taggaagctg aaataaaata
     9121 tagatgaatc aatttggaga gtcaacgcaa tctatggcaa tattttcgaa gctaggggga
     9181 agcattttaa tttcaatgta ctaggcgtct tctacagcta gctagagttt caattgtaga
     9241 tgttctttga aataatatct tagcgattta ttggtattag aagaattaga gaaattcttt
     9301 ctcaataaat aaacatggcg tcaccaaaac tgaagaagcg gtagtgttct tggatggcat
     9361 ggtggtaggc atctaagact aattcacggc ctgcaaaggc agaaaccaac atgaccagag
     9421 ttgattttgg cagatggaag ttggttgaga aggcatccac gaccttccac tcatacccag
     9481 gtttgataaa gatattggtc caaccagaat ctgcttggat ttgcccatca aacttggaac
     9541 caatagtttc caaggtgcgg atagaagtgg ttccgacagc gatgacgcga ccaccatttt
     9601 ctttgacaga gcgaagggtg gcagcagctt cctcagaaag ttgatagaac tctgagtgca
     9661 tttcgtgttc gtccagatta tccacagaaa caggtctaaa ggttccgagt ccgacatgga
     9721 gagtcagata gactagatga acacccttag cttggatttc tgccagcagt tctttggtga
     9781 agtgaagacc agcagtcggt gctgcagcag agccgctttc cttggcgtag acggtttgat
     9841 aacgttcacg gtcatctaat ttttcgtgga tataaggtgg cagaggcatt tctcccagac
     9901 tttccaagac ttctaggaaa attccttggt attcaaagcg gacaatgcgt cccccgtggg
     9961 tcaattcttc tgtaacgaca gcgctgaggc ggccatcacc aaagctgata cgagtaccga
    10021 ccttgaggcg tttggcaggt ttagccagaa cttcccactc gtctccacta gtgttcttaa
    10081 ggaggagaag ttccacatga cctcctgtct ccactttttg accatagagg cgggcaggga
    10141 gaactcgggt gtcgttcatg acaagggcat caccaggttc cagcatatca ataatagagt
    10201 ggaaatgttt atcttgcatt tctcctgtct cacggttgac gatgaggagt ttggaggcat
    10261 cacgtttttc aaggggcgtt tgggcaatca attcctctgg caagtggaaa tcaaaatcag
    10321 ctgtattcat atatctgttc attctttcta agttctaatc ctatccatta taacacgttt
    10381 caagtttgga cgctcttttt ttagaaatta aatcgttttc acttgacaaa aattggtcta
    10441 taccatataa taaatataga cagaaatgga ggatgaaaag atgaaagtta ttaaagttga
    10501 aaaccaagtt caaggtggaa aagttgcttt tgagattttg aaggaaaaat tggctaatgg
    10561 agctcaaact ctaggacttg cgacaggaag tagcccactt gaattttaca aggaaattgt
    10621 tgagagtgac cttgattttt caaatctaac cagtgtcaac cttgatgagt atgtgggcct
    10681 tgatggggac aatccacagt cttatcgtta cttcatgcaa gaaaacttgt tcaaccaaaa
    10741 accatttaaa gaaagtttct tgcctcgtgg tgttaaggac aatgctgaag ctgaagttga
    10801 acgctacaac caaattttgg ctgaccatcc agttgacctc caaatcttgg gaatcggtcg
    10861 caatgggcat atcggcttta atgagcctgg tactccattt gacagtcaaa cgcatctagt
    10921 agaacttgac cagtctacta tcgaagccaa tgctcgcttc tttgccaaga ttgaagacgt
    10981 cccaacccaa gctatttcaa tggggattaa aaacattttg gatgccaagt ctattattct
    11041 ttttgcttat ggtgagtcga aagcagaagc cattgccgga acagtatctg gcccagtgac
    11101 tgagaaccta cctgcaagta gcctccaaaa tcaccctgat gtaaccatca tcgcagatgc
    11161 tgaagcgctt agcttactcg aaaaataaaa aagcaatgtt ctattgaacg ctttcaactc
    11221 ttgtataaat ggaagaaaaa atcaaaatta aaccgcattt ttgcttgaca attattcctt
    11281 ttacgtgtag aatgaaatag atattgaact tgaagggagt gaaaaaaatg tctaaaacag
    11341 tagtacgtaa gaatgaatct cttgacgacg cacttcgccg tttcaaacgt gcggttacta
    11401 aagctggtac tcttcaagaa acacgcaaac gtgaattcta tgaaaaacct tctgtaaaac
    11461 gtaaacgtaa atcagaagta gctcgtaaac gtaaaaaatt ctaattgaaa tgaaaggcta
    11521 gagaaatcta gtcctttttc ttttaaataa atactccaaa gcctgcaaaa atctgaaact
    11581 tcctcctaca atttgatata atagagagaa gaattcattt gaaggaggaa atgatgtcgg
    11641 ttttagtaaa agaagtgatt gaaaagctta gactagatat tgtctatggt gaaccagaat
    11701 tgcttgaaaa ggaaatcaat acagcggata ttacgcgacc tggtcttgaa atgacaggct
    11761 attttgacta ctatacacca gagcggattc aacttttggg gatgaaggag tggtcttatc
    11821 tgatcagcat gccttccaac agccgttatg aagttttgaa aaaaatgttt ctacctgaga
    11881 caccagcagt cattgttgcc cgtggtttgg tggttccaga ggagatgtta aaggctgcta
    11941 gagaatgtaa gattgctatt ttaaccagcc gtgcagctac cagtcgttta tctggagagt
    12001 tatctagcta tctggattct cgtttggcag aacgtaccag tgtgcacggt gtcttgatgg
    12061 atatttatgg gatgggcgtc ttgattcagg gagatagtgg aattggtaag agcgagacag
    12121 gtcttgagct tgtcaaacgt ggtcaccgtt tggtagccga tgaccgtgtc gatatctttg
    12181 ccaaggatga gattactctc tggggtgaac cagctgaaat tttgaaacac ttgattgaaa
    12241 ttcgtggggt tggtattatc gatgttatga gtctctacgg tgcgagtgct gtcaaggatt
    12301 cttcacaggt tcagcttgct gtctatttgg aaaattacga tacgcataag acctttgatc
    12361 gtcttggaaa caatgcagag gaacttgaag tttctggcgt agccattcct cgtattcgta
    12421 ttccagttaa aacaggtcgt aatatctctg ttgtgattga ggcagctgcc atgaattatc
    12481 gtgccaagga aatgggcttt gatgctaccc gtttgttcga cgaacgactg acaagtctca
    12541 tagctcgaaa tgaggtgcaa aatgcttgat ccaattgcta ttcaactagg acccctagcc
    12601 attcgttggt atgccttatg tattgtgaca ggcttgattc ttgcggttta tttgaccatg
    12661 aaagaagcac ctagaaagaa gatcatacca gacgatattt tagattttat cttagtagcc
    12721 tttcccttgg ctattttagg agctcgtctc tactatgtta ttttccgatt tgattactat
    12781 agtcagaatt taggagagat ttttgccatt tggaatggtg gtttggccat ttacggtggt
    12841 ttgataactg gggctcttgt gctctatatc tttgctgacc gtaaactcat caatacttgg
    12901 gattttctag atattgcggc gcctagcgtt atgattgctc aaagtttggg gcgttggggt
    12961 aatttcttta accaagaagc ttatggtgca acagtggata atctggatta tctacctggc
    13021 tttatccgtg accagatgta tattgagggg agctaccgtc aaccgacttt cctttatgag
    13081 tctctatgga atctgcttgg ctttgccttg attctgattt ttagacggaa atggaagagt
    13141 ctcagacgag gtcatatcac ggccttttac ttgatttggt atggtttcgg tcgtatggtc
    13201 atcgaaggta tgcgaacaga tagtctcatg ttcttcggcc ttcgagtgtc ccaatggctg
    13261 tcagttgtct ttatcggtct cggtataatg atcgttattt atcaaaatcg aaagaaggcc
    13321 ccttactata ttacagagga ggaaaactaa atgttagaag ttgcatatat tcttgttgcc
    13381 ctagctgtga ttgtcttttt ggtctatctg atcattactg tacaaaagct tggtcgtgtc
    13441 atcgatgaaa cagaaaagac gattaaaacc ttgacttcag atgtggatgt gaccttgcat
    13501 cacaccaatg agttgttggc taaggtcaat gtcttggcag atgatatcaa tgtcaaggtg
    13561 gctacgattg atccactctt cagtgctgtt gcagatttat ctctatctgt ttcagacctc
    13621 aatgaccatg cgcgtgtctt gagcaagaaa gcttcatcag ctggttcaaa aacactcaag
    13681 actggtgcaa gtctgtcagc tcttcgtctt gcaagtaaat ttttcaaaaa ataaaaaagg
    13741 agaatcctta tgggtaaatt atcctcaatc cttttaggaa ccgtttcagg tgcagctctt
    13801 gccttgtttt taacaagtga taagggcaaa caagtttgca gtcaggctca agattttcta
    13861 gatgatttga gagaagatcc ggagtatgcc aaggagcaag tctgtgaaaa actgacagaa
    13921 gttaaggagc aggctacaga ttttgttctg aaaacaaaag aacaggttga gtcaggtgaa
    13981 atcactgtgg acagtatact tgctcaagct aaatcctatg cttttcaagc gacagaagca
    14041 tcaaaaaatc aattaaataa tctcaaggaa caatggcaag aaaaagccga agctcttgat
    14101 gactcagaag agattgtgat tgatataaca gaagaataaa ccatcaccat ctccggacgg
    14161 actatgtatc tggggatggt gatttttatc tggaatctag tctttgtggt ataataatta
    14221 ctatgcagaa aaaaccaacg tcagcctatg tgcacatccc attttgtacc cagatttgtt
    14281 attattgtga tttttcaaag gtcttcatca aaaatcagcc agtcgacagc tatttagagc
    14341 atctgctgga agagtttcgt tcttatgata ttgaaaagtt gtcaaccctt tatatcggtg
    14401 gtggaacacc gacagccctg tcggctccgc aactggaggt gttactgaat ggcttgacta
    14461 aaaacttgga tttgtctgtc ttggaagagt tgaccattga agccaatcca ggcgatttgg
    14521 atgcggataa gatagctgtt ttgaaaaatt cggctgtcaa tcgtgtttcg ctaggtgtcc
    14581 agacctttga tgataagatg ttgaaaaaga ttgggcgcag tcatttggag aaggatattt
    14641 atgaaaatat cgatcgcctg aaactggctg gttttgacaa catctccatt gatttgattt
    14701 atgctctgcc tggtcagacc atggagcaag taaaggaaaa tgtggctaaa gccattggat
    14761 tggatattcc ccacatgagt ttgtatagtt tgattttaga aaaccatacg gtctttatga
    14821 accggatgcg acgtgggaaa ttgcctctgc ctaaggagga actagaagcg gagatgtttg
    14881 agtacatcat tgcagagctg gagcgagcga gttttgagca ttatgagatt tctaatttct
    14941 ccaaacccgg ctttgaaagt cgtcataatc tcatgtactg ggacaatgct gaatactatg
    15001 gtattggtgc aggggcatct ggttatgtca atggagtacg ctataaaaat catggtccca
    15061 ttcgtcatta tctcagtgcg gttgaggaag gcaatgcttg tattacagaa gatcacctga
    15121 gtcaaaagga gcaaatggaa gaagaaatgt tcttgggact ccgcaagaaa tccggggttt
    15181 ccatggcgcg atttgaggaa aaatttggac agtcttttgc tggactttat ggagaaattg
    15241 tcagagattt ggttcaacaa ggcctcatgc agattgaggg tgaccacgtt cgcatgacaa
    15301 agagaggtct ctttttggga gatactgtag cagaacgatt tattttggag taggatcatg
    15361 ggcttaactt atcaaatgaa aatgaaaatt ccttttgata tggctgatat gaacggtcat
    15421 atcaaacttc cagatgtgat tttgctgtca ctgcaagttt cagggatgca atcgattgaa
    15481 ctggaagtta gtgataaggc cattttggaa gactataatc tggtctggat tatcgcagaa
    15541 tatgatattg aggtggttcg tttgcctcgt tttgcggaag aaattaccat cgaaacggaa
    15601 gccttgagct acaatcgact tttttgctac cgtcgcttta ctatttataa tgaagcgggg
    15661 caggagctca tccatatgat ggcgaccttt gttctcatgg accgcgacag tcgaaaagtc
    15721 catgctgttg aacctgagat tgtggctcct taccagtctg attttgataa aaaacttatc
    15781 cgtggaccga agtatgaatc cttggaagag ccgatcagca aggattacca tgttcgtttt
    15841 tacgacttgg atatgaatgg tcatgtcaat aacagtaaat acttggactg gatttttgag
    15901 gtcatgggag cggatttttt gacccactat attcccaaga aaatcaacct caagtatgtc
    15961 aaggaagttc gaccaggtgg ggtgattaca tcggctgttg aacggactgg actggaaagc
    16021 aagcatgaaa ttacaagtga tggggttatc aatgcccaag caatcattac ttggcaagaa
    16081 ataaaaaagg tttagggaga aatagatgaa atataaaggc tatttaattg atttagacgg
    16141 aaccatttat aaggggaaag accgaatccc tgctggagag acttttgttc atgaattgca
    16201 aaagcgggac attccctatc tctttgtaac caacaataca acccgcactc cagagagtgt
    16261 taaggagatg ttggctcaga attttaatat cgatacgcct ctatcgactg tctacacagc
    16321 gactttggca accatcgact atatgaatga tttggggctt gaaaagactg tctatgtcgt
    16381 cggagaagca ggactcaagg aagccatcaa ggcggctggt tatgtggaag acaaggaaaa
    16441 ccctgcctac gtggtagttg gtctggattg gcaagtcgac tatgaaaaat ttgccacagc
    16501 aactcttgct attcaaaagg gtgcccattt tatcggaacc aatcctgacc tcaacatccc
    16561 gacggaacgt ggtcttttgc caggtgctgg ctcactgatt acgctgcttg aagtagcgac
    16621 acgagtgaag ccggtttata tcggaaaacc aaatgccatc attatggaca aggcggttga
    16681 gcacttaggt ttggaacgtg aagagttaat catggttggg gacaattatt tgactgatat
    16741 ccgggctggg attgacaatg gcattccaac gctcttggtg acgacaggtt ttactaaggc
    16801 agaagaagta gctggcctgc caatcgcacc gacacatgtg gtttctagcc ttgcggagtg
    16861 ggattttgat gaaaactaaa ttgacctttt ggggctctat gctctttctc ctctccctct
    16921 caatccttct gaccatttat ctggcttgga ttttctatcc tatggagatt cagtggctaa
    16981 acttaacgaa tcgagtctat ctaaaaccag aaaccattca atacaatttt catatcttga
    17041 tgaattatct gaccaatcct tttagtcagg tcttacagat gcctgatttt cgttcgtcag
    17101 cagctggtct gcaccatttc gcagtggtca agaatctctt tcatttggtt cagctagtag
    17161 ctctagtgac actgccaagt ttctatgtct ttgtcaatag gattgtgaaa aaggactttt
    17221 tgtctcttta tcgaaaaagt ctcctggctc tagtagtctt acctgtgatg attggacttg
    17281 ggggagtttt gattggtttt gaccaattct ttactctttt ccatcaaatt ctctttgtgg
    17341 gagatgatac ctggcttttt gatccagcca aggatcctgt tattatgatt ttgccagaga
    17401 ccttctttct tcatgccttc ctcctctttt ttgccctcta tgaaaacttc tttggctatc
    17461 tgtatctgaa aagtcgtagg aagtgaaagg aaagatgttt ttaatttaca tatataaaaa
    17521 tatatatcat ttaaaaccat cgttaagagt gaattaacca aatccaattg tgtcaatcgt
    17581 tcgcaaaaag cctatttttc ttgaaaaaat aggctttttt tctaaaaatc cctagtcaag
    17641 cgctttattt ttttgtataa tagaagtagc aaagtataga taagaagaga aaagcatgat
    17701 tacactattt ctatcaccga gctgtacatc atgtcgtaag gctaaggcct ggttagaaaa
    17761 acataaggtt ccctttgtgg aacacaatat tatgaccagt cctttaacaa gaaaagaatt
    17821 gcaacacatc ctttccttga ccgaaaatgg tactgatgac atcatttcaa ctcgttcaaa
    17881 aatttttcaa aaattgaata ttgatgtaga gagtatttcg gtatcggaat tgcttcattt
    17941 gattgagcag tatcctagtc ttttgcgtcg tccaattatt attgatgcca agcgtatgca
    18001 aatcggtttt aatgaagatg agattcgtgc ttttctccct cgtagttatc gtaagcaaga
    18061 actaaaagaa gcaagaatga gagctggtat tagttaatga acaaacagta tagttaccca
    18121 ctagatttgt cgtggagcac tgaagaactt gcttcagtgc tttctttttt taatgatgtt
    18181 gaagctgcct atgaaggcaa agtagaggct aaaaagttac tggactccta taagggattc
    18241 aaagcggtcg tgccaagcaa gagcgaagag aaacgtttgg gacgagaatt tgaaacggtt
    18301 agtggctatt cactttaccg agcagttcag gctgccaaag aaaaagggga aggaaagatt
    18361 tctcttggaa agtaaatttg aatttgctaa agagcttgtt aagaaagcag gtcagtacat
    18421 tcttgaccat atgcaggaag acttgcgtgt tgaaaccaag tcctctccaa cagatttggt
    18481 gactagactg gacaaagaag ttcaggaact cttggttggt gagattttgt cccgttatcc
    18541 tgaggataag atttgtgctg aagaaggttg tctgcgagcc tcggttcaag agggcaaggt
    18601 ttgggtcatt gatcccattg atggtaccaa taattttgta gcccagcagg aagattttgc
    18661 tgttatgatg gcttattttg aaaatggtca gggacagttt ggtctgattt atgatgtggt
    18721 caaaggggat tgttaccacg gtggtgggga atttccagtt tgtctaaatg ataggcccct
    18781 agctcctttt aaaactaaac cacttggaga ttttctcatt gcagggaata gtggtatgct
    18841 ggaaaccaat gaatgggggc tggctgattt gagccgagcg gttcttggtg ttcgtgtcta
    18901 tggaagtgcg gccattagtt ttgccaagat tttgtcaggg cgtttgttga cctatctcac
    18961 ttatctgcaa ccatgggatt atgccgcagc tagtatttta ggggaaagtc tgggctatcg
    19021 ggttgtgacc ctttttggtg aagctcctga ttttcaaacc agacagcctg tcatgatggt
    19081 gcctcttgag atgcaggagg aaattcagtc ctatatttac gaaaggaaaa gaacttaaat
    19141 gcaatttcca gaaggatttg ttgaaaaata taaagaaata ctaggagatg aggcaagaaa
    19201 ttttcttgcc tcttttgagg aggaagcggt ttcggccttt cgggtcaatc ccttaaaaga
    19261 agagcaactt tccttttctg atgccattac tcaaacccct tggggccact atgggaaggt
    19321 ttcagggaaa tcgcctgagc atgctacagg tttagtttat tcgcaagaac ctgctgctca
    19381 aatggtggct caagtagccc aacccagtcc tggtatgaag gtcttggact tggctgctgc
    19441 accggggggc aaatcaactc aactggcagc ctatctagca ggggaggggc tacttgtttc
    19501 caatgaaatt tcaagcaaac gggctaagat tttggttgaa aacatggagc gttttggagc
    19561 gacaaatgtc gtggtgacca atgaatctgc cgaccgcttg gtcaaggtct ttaaaggcta
    19621 ttttgactta atcgttcttg atgccccttg ctctggtgaa ggaatgtttc gtaagcaacc
    19681 tgatgctatg gactattgga gcttagatta tccgagtcaa tgtgctagct tgcaaagaga
    19741 aattctggag gatgcagtga ccatgttagc tgaaggtggt cgtctggttt attcgacctg
    19801 tacctgggca cccgaggaaa acgaagagat tgtcaattgg ttgctggaag agtatgattt
    19861 tgacttgttg ccagtagagc atatcaatgg aatggtagct ggtattgacc taccagaaac
    19921 ggctcggatg taccctcatc agtttaaggg agagggtcag tttgttgccc atctacagtt
    19981 taagggtaac aatccagctc ctaaatttaa ggcaagtaag agtaacctca gccgtgaaca
    20041 agttgccttg tggcaggaat ttgcccaaaa ccatttgaag gtcaatctac cgggtatctt
    20101 gcagactttt ggagaccagc tttatctctt gccagaactt ttgccagatt tagggaagct
    20161 caagattgct cgcaatggac tgcatctggg cacttttaag aagaaacgct ttgagcccag
    20221 tttcgctctt ggtttagcct tgaaaccgag tcaggtcgaa cagtcggttg aaattggcca
    20281 agaagcgttt gtcaagtatg cggctggaga aatcgttcag ctggcagaaa gtctgccaaa
    20341 tggttggtac caagttttgg ttaaaggcaa tggcttgggc tttgcaaagg ttactggaaa
    20401 tgttttgaaa aattattttc caaaaggcct cagattcaaa tgaaaatgct agtcaaatat
    20461 cttattctat gttatagtga aagtatggat ttttttagta ggatgattct tgatatcttg
    20521 attgccatta catgtagttt tactactcaa tgaaaatcaa agagcaaact aggaagctag
    20581 ccatagatag ctcaaaacac tgctttgaag agattttcaa agagtacaag aagtttagtt
    20641 attagcgttc ttaccgcttg taaactagat ttctcataaa atagaatctt ttccttttag
    20701 ttgtaaacta gtctgggaga gtagagaggt ttgagatacc tttctagctt ttggattatc
    20761 atctaaggag agtaatttcc cttgcattaa aaaggggaaa aagagacacg aaatgactat
    20821 aatgggtgac aatgggggaa gggatagaca agagatttta tccacatatg aaaaaaggag
    20881 gttaggaaag agtaatatag cctatattat ataaataatc aattgcgcag aaatttggta
    20941 agaattcatg cgtcaactca taaagaacta cttaaaaaat tcacagtatt cataattatt
    21001 ttcgaggaga aaaacagtga aaaaaagaaa aaagcttgct ctgtctctta tcgctttttg
    21061 gctgacggct tgtttagtag gctgtgctag ctggattgat cgtggagaat ccataacggc
    21121 tgttggctca actgccttgc aacccttggt tgaagtagcg gcagatgaat ttggcacgat
    21181 ccatgttgga aaaacggtca atgtccaagg gggaggttct ggtacaggct tgtcccaggt
    21241 tcagtctggg gcagttgata taggaaactc agatgtattt gctgaggaaa aagacggaat
    21301 tgatgcttct gctcttgttg accacaaggt cgcggtagct ggcttggctc tgattgtcaa
    21361 taaggaggtt gatgttgata acctaacgac agagcaactt cgtcaaatct tcataggtga
    21421 ggtaaccaat tggaaagagg ttggtggtaa ggacttaccc atctctgtta tcaatcgggc
    21481 agccggctct ggctctcgtg ctacctttga tactgtcatt atggaaggtc agtctgccat
    21541 gcaaagtcag gagcaggatt caaatggagc ggtaaaatca atcgtatcaa aaagtccagg
    21601 agctatctct tatttatctc ttacctatat agatgattcg gtcaaaagca tgaagttgaa
    21661 tggctatgac ttaagtccag aaaatataag tagcaataat tggcccttgt ggtcttatga
    21721 gcatatgtat acattggggc agcccaatga gttggctgca gaatttctca attttgttct
    21781 ctcggatgag acccaagaag ggattgtcaa aggattgaag tatattccga ttaaggaaat
    21841 gaaggttgaa aaagatgctg ccggaactgt gacagtgttg gaagggagac aataatgaat
    21901 caagaagaat tagctaagaa aatgttgctt ccatcaaaga attctcgtct ggagaaatta
    21961 ggaaaaggtt tgacctttgc ctgtctttct ttgatagtca tccttgtggc catgattttg
    22021 gttttcgtag cgcaaaaagg cttgtcgacc ttctttgtca atggtgtgaa tatctttgac
    22081 tttcttttgg gaggaacttg gaatccttct agtaaagaat ttggtgccct tcctatgatt
    22141 ttgggttcct ttatcgttac cattctctca gcccttatcg caacaccctt tgctattggt
    22201 gcagcagttt ttatgaccga agtatcacca aaaggggcga agattttgca accagctatt
    22261 gaactcctgg ttgggattcc ttcagtagtg tacggattta ttggcttgca agtcgtcgtt
    22321 ccctttgttc gcagtgtctt tggtgggact ggttttggga ttttgtcagg gatttccgtc
    22381 ctctttgtca tgattttgcc gaccgtaacc tttatgacaa cggatagctt gcgtgcggtt
    22441 cctcgttatt atcgtgaggc tagtttcgct atgggagcca ctcgctggca gactatctgg
    22501 cgtgtgatct tgaaggcggc ccgttctggt attttcactg cagtggtctt tgggatggcg
    22561 cgtgcctttg gtgaggctct agctatccag atggttgtcg gaaactcagc tgttatccca
    22621 acttccttga ccacaccagc tgcaacttta acttctatat taactatggg aattgggaac
    22681 actgtcatgg gaactgtaaa taataatgtt ctctggtcac tggccttggt actgctcttg
    22741 atgagcttag tttttaacag tgtgattaaa ttgattacga aagaaagagg aaagaaaaat
    22801 tatgcgcgct aagaaattag ataaacttgc aacagctgtc ctctatacga ttgctagcat
    22861 cattgtgaca atcttggctt ccttgattct ctatatcttg gttcggggct tgccccatat
    22921 ctcttggtct ttcttgactg gaaggtcttc tgcttttcaa gcaggtggtg ggattggcat
    22981 tcagctttac aattcctttt tcctattggt cattaccttg attatttctg tacctctttc
    23041 tatgggagct gggatttact tggctgaata tgctaaaaaa ggtcctgtta ccaactttgt
    23101 gcgaacttgt attgaaatct tgtcctcttt accatcagtg gtggtgggtc tctttggtta
    23161 cttgatcttt gtagtccagt ttgagtatgg attttcaatc atttcaggtg ctttggcctt
    23221 gacagtcttt aacttgcctc agatgacgcg taatgtagaa gatagtttga aacacgttca
    23281 ccatacccaa cgtgaggctg gtctggctct tgggatttct cgctgggaga cagtggttca
    23341 tgttgttatt ccagaagcgc ttccaggtat tgtaacgggt gtcgtcttgg catctggtcg
    23401 tatctttggc gaagctgcag ctctgatcta tacagcaggg caatcggcgc cagctcttga
    23461 ctggtctaac tggaatatcc tcagtgtgac tagccccatc tctatcttcc gtcaagcaga
    23521 aaccttggct gtccatatct ggaaagtcaa tagtgaaggc actattccag atggaaccat
    23581 tgtatcagca ggttctgccg ctgtgctcct gatctttatc ctgattttta actttggagc
    23641 tcgtaagttc ggaagctatc tacacaagaa attaaccgct gcctaaagga gaagccatgt
    23701 caacatataa ctgggatgag aagcatatcc ttacctttcc tgaagaaaaa gtagcccttt
    23761 ctactaagga tgtccatgtt tattatggta aaaatgaatc cattaagggg attgatatgc
    23821 aatttgaaag aaataaaatt acagctttga ttggtccgtc gggatcgggg aaatctacct
    23881 acttacgcag tctcaatcgc atgaatgata ccattgatat tgctaaagta actgggcaga
    23941 ttctctatcg tggaattgat gtcaaccgtc cagaaatcaa cgtttatgaa atgcgtaaac
    24001 acattggaat ggtttttcaa cgccccaatc catttgctaa gtcaatttac cgtaatatta
    24061 cctttgcgca tgaacgtgct ggagttaagg ataagcaagt cctagatgaa atcgtagaaa
    24121 cctcccttcg tcaggctgcc ctctgggatc aggttaaaga cgatctccac aagtcagcct
    24181 tgaccttatc aggtggtcag caacaacgtc tctgtatcgc tcgtgccatc tctgttaagc
    24241 cagatatcct cttaatggat gagccagcct cagccttgga tccgattgcg accatgcaac
    24301 tagaagagac catgtttgag ctcaagaaaa actttaccat catcattgta acgcataata
    24361 tgcagcaggc tgctcgtgca agtgactata caggcttctt ttacttgggt gatttgattg
    24421 agtatgacaa gactgcaact attttccaaa atgccaagct acagtccacc aatgactatg
    24481 tatctggtca ctttggttag aaaggaaacc gtatgacaga tgcgatttta caggtatcag
    24541 acctgtccgt ttattataat aaaaagaagg ctttgaatag tgtttcccta tctttccaac
    24601 ctaaggaaat tacagccttg attggtccat ctggatcagg gaagtcaacc ctcctcaagt
    24661 ctctcaaccg catgggagat ctcaatccag aggtgaccac aactggatcc gtggtgtaca
    24721 atggtcacaa catctacagt ccgcgtacag atacggttga attacgtaag gaaatcggaa
    24781 tggttttcca acaacctaat cctttcccta tgactatcta tgagaatgtt gtctacgggc
    24841 ttcgtatcaa tggaattaag gataagcagg ttctggatga agccgtagaa aaagccttgc
    24901 aaggtgcctc tatctgggat gaggtcaagg atcgtctata tgattcagct attggattgt
    24961 caggtggtca acagcagcgt gtctgcgtgg cccgtgtctt ggcaactagt cctaaaatca
    25021 tcctcttgga tgagccaact tcggctttgg atccgatttc agctggtaag attgaggaaa
    25081 ccttgtatgg tctaaaagac aagtacacca tgcttctggt aacccgttcc atgcagcaag
    25141 cttcacgtat ctctgataag acaggatttt tcctagatgg agatttgatt gaatttaatg
    25201 ataccaagca gatgttcctt gatccccaac acaaggaaac ggaagactat attacaggaa
    25261 aatttggata aggagatgaa agatgttacg atctcaattt gaagaagatt tagagaaatt
    25321 acataaccag ttctacgcta tgggacaaga agtgctctca caaatcaatc gtacggtacg
    25381 tgcttttgtc acgcatgacc gtgacctggc aaaagaggtc atagaagatg atgcagaagt
    25441 aaatgaatac gaagtgaaac tggaaaagaa atcatttgaa atgatcgcac tccaacaacc
    25501 agtctctcaa gatttgcgta cagtcttgac tgtccttaag gctgtatcag atgtggagcg
    25561 tatgggggat cacgctgtag ccattgccca ggcaaccatc cgtatgaagg gggaagagcg
    25621 catcccagct gtagaggaag aaattaaaaa aatgggacgt gaagttaaaa gcgttgttga
    25681 agcagcactt gatctttatc ttaatggttc tgttgacgac gcataccggg tggcctccat
    25741 ggatgagcaa attaaccact attttgaaac tatccgtgac cttgcgactg aagagattaa
    25801 gaaaaatcca gaagccattg ttacgggtcg tgattatttc caagttattt cctacttgga
    25861 gcgtatcggt gactatgcta aaaatatctg tgaatgggtt gtctactttg aaacaggtaa
    25921 gattgtcgaa ctataaaata gtttaattct gtataaaaag gagcttgaaa tcaactgatg
    25981 gctccttttt ttgaacgaaa aaatattttt gagataaaaa tttaaaaaac acttgacaag
    26041 taacttggat atcgttataa ttatacaaaa ttaacagaga ggttgtttat ttatgaaatc
    26101 aaaaaaatgg atatttgttt tatgtaattt tcttgcaagt ttcttcttag tagcttgcca
    26161 gtcaggttct aatggttctc agtcagctgt tgaggccatt aagcaaaagg ggaaattagt
    26221 tgtggcaacc agtcctgact atgcaccctt tgaatttcaa tcattggttg acggaaagaa
    26281 tcaggtagtc ggtgcagaca tcgacatggc tcaggctatc gctgatgaac ttggggttaa
    26341 gttggaaatc tcaagcatga gttttgacaa tgttttgacc agtcttcaaa ctggtaaggc
    26401 tgacctagca gttgcaggaa ttagtgctac tgacgagaga aaagaagtct ttgatttttc
    26461 aatcccatac tatgaaaaca agattagttt cttggttcgt aaggctgatg tggaaaaata
    26521 caaggattta actagcctag aaagtgctaa tattgcagcc caaaaaggga ctgttccaga
    26581 atcaatggtc aaggaacaat tgccaaaagc tcaattaact tccctaacta atatgggtga
    26641 agcagtcaat gaattgcagg ctggaaaagt agatgctgtt catatggatg agcctgttgc
    26701 acttagttat gctgctaaaa acgctggctt agctgtcgca actgtcagct tgaagatgaa
    26761 ggacggcgac gccaatgccg ttgctcttag aaaaaatagt gatgatttga aagaagtggt
    26821 agacaaggtc atccaaaaac ttaaggatga aggaacttac caaagctatc ttgaaaaagc
    26881 agcaagtcta actgaagttg aagaataaga aaaagcagag ttggatgtca ttccaattct
    26941 gcttttaaat agtttaaaac attttccaga ttgtctaggg acaccttggc aaattgataa
    27001 ggacaggtgc ttaaataggc ctcttcaaag aagtccaagc ccagttgact gtgtttgaga
    27061 ctggcgattt taggatactg tctcaggtct agcaataaac catcgtgtag gggataatga
    27121 ggaaggggac aaggtgtttt agttatcctt tcctcgattt gtttttggta agattcatga
    27181 ttggtcaagc gagccaaacg atttttttca aacaattgac tgtcaatata gagtgacagg
    27241 gccttttgca taatgaggtt gctgtcgtag tctaggatat ttttgtaggc cacaaatgct
    27301 tctttgatag catttggaag aatgagtgct gtaatacgaa gggcaggaaa aaggctggtc
    27361 gagaaggact tgatataaat gacacgctcc tctgtatcaa gatagtggaa ggtttggccc
    27421 ttcttggagt ccaaatcacc cagataatcg tcctctacga tatagacatc atacttggca
    27481 gctaagttaa gaatagatcg tttgtcctgc tcagaatagg aatgtcccag aggatagtga
    27541 aatcggggaa tggtgtagaa aaatttaatt tttcctgttt tgaagtggcc ttccagctcc
    27601 tccaagtcaa tcccatcaat gcctcgttca atcgtttgat agtccagccc ctgtgcaatc
    27661 aagaggcgat tcatccgatg gtaggttggc tgttccacca agatttcctt ggcttgtcta
    27721 ggaaaggata tttgagagag gataaacaag gcttgttggg ttccagaagt cagtactagt
    27781 tggttagcct tgcagtagag agcttgctca aagaggagtt tgtgaatgga ctgtcttagg
    27841 tcttctaatc cttcttgatt gtcatagtag ttgaagaggt agttttctcg gccaatcaag
    27901 gtttcattga cacagagtcg gaaatcgtca taggcactgg catgttcgtc ggtaacctcg
    27961 atttctaggt cttgatgttg cccttgttct aatacatagt agccactctg aggcttggca
    28021 tagaggtatt gttcgtgccg taattccagc agggctcgtt gaatggtgtc cttgctgcag
    28081 tgaaagtcaa ggctcagttg acggatagaa ggcaggcgac tacccgtcgg aaatcgttca
    28141 gactcgatac catttttcag ataggaaacg acctctttgt acttgctttg tttcttcatt
    28201 ccagacctcc cttgattttg ttacattgta cccttttttt tccttcttgg caatgtctag
    28261 agcgtttctc tcgttcacat ctaggggcaa atgtggtata cttaggagta agatttatag
    28321 aataacagac aagaaagtga atggataaga acgtgcagga accagtgaaa ttatttcaat
    28381 acaatactct tggagccttg atggctggcc tttatggtgg tactatgaca gtaggagaat
    28441 tgctagaaca tggtgacctt ggtttgggaa ccttggattc cattgatggg gaattgattg
    28501 tcttggatgg caaggcttat caggccaaag ggtcaggaga ccagccagaa attgtggaag
    28561 tgtcaccaga tgcccttatt ccttacgctg cagtggtacc gcatcaggca gaggtcattt
    28621 tccgccagcg ctttgagatg acagacaagg aattgaaaga acgaattgag tcttattatg
    28681 atggggaaaa tcttttccgt tctatcaaga ttcgggggga attttcacat atgcatgtgc
    28741 gtatgattcc taagtcaaca cccgatacca agtttgctga tgtcgcaacc catcaaccgg
    28801 aatatagtcg tgacaatgtt gcggggacta ttgttggttt ctggacgcct gagattttcc
    28861 atggggtcag tgtggcaggc taccatctgc acttcatatc agatgatttg accttcggtg
    28921 gacatgtcat ggattttgtc atcaaggaag gcattatcga ggtgggagca gttgaccagt
    28981 tggaccaacg tttcccagtc caagaccgtc aatacttgtt tgctaagttc aatgttgacg
    29041 agatgaaaaa agatattgaa aaggcagaat aggagaagaa aatgaccatt catatcatta
    29101 ttaccatgtt gctgttgcta gcttttctga taggaagcat ttggtttgcc aaaaagaaat
    29161 accagattaa tctagctgtc ttgggcttgg gtgcagtcgc tttctttgtc tcttcgcaga
    29221 ttttggaaaa actggtgcat atcttgattt tgcatcctca aaaaagacgg tagtattgcc
    29281 ctcttgcaag atcacccgct tgtctatatt atctatggcc tagctatggc agcatttttt
    29341 gaggaaacgg ctcgtcttgt tttcttcaaa tggttggaga aaaagagaag tttggaaaag
    29401 gcagacgcct tggcctatgg actggggcat ggtggcttgg agttgatttt tctaggcctt
    29461 actagtttac tcaatcttta cattgttctt tcggcagttc aaactcagaa tccacaggtt
    29521 atgcaattac tgtctgaaaa tatgttaaaa accattcagt cactttcggt ctggcagatt
    29581 tatttgcttg gttttgagcg aatcttggcg cttggtttcc aattactttt gacagtttgg
    29641 gtttaccaag ctgttcgcca gaagaaatgg atttatctcc tagcagccta tggcttgcat
    29701 gccttctttg atctggcacc atctctttcc caagtaggct ggttgacaaa tccagtcttg
    29761 gttgaagtga ttctagcact ggagctcgtt ctggtcgcct atggaaccaa ggaaatcttt
    29821 tgtaaaaaat cataaaaagg gggaaacctc tttttcttat gcaaaatcca aacaaggtat
    29881 ttttatggtc gtcaaatgtc tctaaaaatg gtataatgga atgaattttg taaaaggaag
    29941 agtgacatgt ctgtaagaga aaaaatgctt gaaatcttag aaggaattga tatccgtttt
    30001 caggaaccct tgcatagcta tagttataca aaagtaggtg gagaggctga ttatttggtc
    30061 tttccacgaa atcgttttga gttggctcgc gttgtgaaat ttgccaacca agaaaatatc
    30121 ccttggatgg ttcttggcaa tgcaagcaat atcatcgttc gtgatggtgg gattcgtgga
    30181 tttgtcatct tgtgtgacaa gctcaataac gtttctgttg atggctatac cattgaagca
    30241 gaagctgggg ctaacttgat tgaaacaact cgcattgccc tccgtcatag tttaactggc
    30301 tttgagtttg cttgtggtat tccaggaagc gttggcggtg ctgtctttat gaatgcgggt
    30361 gcctatggtg gcgagattgc tcacatcttg cagtcttgta aggtcttgac caaggatgga
    30421 gaaatcgaaa ccctgtctgc taaagacttg gcttttggtt accgccattc agctattcag
    30481 gagtctggtg cagttgtctt gtcagttaaa tttgccctag ctccaggaac ccatcaggtt
    30541 atcaagcagg aaatggaccg cttgacgcac ctacgtgaac tcaagcaacc tttggaatac
    30601 ccatcttgtg gctcggtctt taagcgtcca gtcgggcatt ttgcaggtca gttaatttca
    30661 gaagctggct tgaaaggcta tcgtatcggt ggcgtagaag tgtcagaaaa gcatgcagga
    30721 tttatgatca atgtcgcaga tggaacggcc aaagactacg aggacttgat ccaatcggtt
    30781 atcgaaaaag tcaaggaaca ctcaggtatt acgcttgaaa gagaagtccg gatcttgggt
    30841 gaaagcctat cggtagcgaa gatgtatgca ggtggtttta ctccctgcaa gaggtagtgg
    30901 ggacctgaca gagccccgat cggttaatct atgaaaagaa ggaatttatg ccaattgaaa
    30961 aaaccaatta tcgaattcaa aaacgtctct aaagtttttg aagacagcaa caccaaggtt
    31021 ctcaaagaca tcaactttga gttggaagaa gggaaattct acacccttct aggtgcatct
    31081 ggttcgggga aatcaactat cctaaacatt attgcaggtt tactggatgc gacgacagga
    31141 gatatcatgc tagacggtgt tcgtatcaat gatattccaa ccaacaagcg cgacgtacat
    31201 accgtcttcc aatcctatgc cttgttccca catatgaatg tgtttgaaaa tgttgccttt
    31261 ccacttcgct tgcgtaaaat tgataagaaa gaaatcgagc agcgtgtagc ggaagttctc
    31321 aagatggttc agttggaagg ttatgaaaaa cgttccatcc gcaaactttc tggaggacaa
    31381 cgtcagcgtg tggccatcgc ccgtgctatc atcaaccaac cccgtgtggt cttgttggac
    31441 gagcctttat cagcgctgga cttgaaattg agaacagaca tgcagtacga attgcgtgaa
    31501 ttacaacaac gattgggcat tacctttgtc tttgtcactc acgatcagga agaagctctt
    31561 gccatgagtg actggatttt cgttatgaat gatggcgaga ttgtccagtc tggaacccct
    31621 gtggacatct acgatgagcc aatcaaccac tttgttgcca cctttatcgg ggagtcaaac
    31681 atcttgccag gtaccatgat tgaggactac ttggtcgaat ttaacggcaa acgctttgaa
    31741 gcggttgatg gtgggatgaa gccaaatgaa cctgttgagg tcgttattcg tccagaggac
    31801 ttgcgcatta cccttcctga agaaggcaaa ctccaagtta aggtcgacac ccagctcttc
    31861 cgtggagttc attatgaaat tatcgcctat gacgaacttg gaaatgaatg gatgatccac
    31921 tcaacccgta aggccatcgt gggtgaggaa atcggtctgg actttgaatc agaagacatc
    31981 cacatcatgc gtctcaatga aaccgaagaa gagttcgatg ctcgtatcga agaatacgtg
    32041 gaaatcgaag agcaagaagc aggtctgatc aatgcgatcg aggaggaaag agatgaagaa
    32101 aacaagctct aaactctttg tagtgcccta catgctttgg attgccctct ttgtattggc
    32161 acccttggtc ttgattttcg gacaatcctt tttcaacatt gaaggccagt ttagtttaga
    32221 aaattataaa tcttactttg cgtcacaaaa cttgacctac ctcaaaatga gtttcaactc
    32281 agtgctttat gcaggcattg tgacctttgt gaccttgctt atcagctatc caacagccct
    32341 ctttttgacc cgtctcaagc accgtcaact ctggctcatg ctgattatcc ttcctacctg
    32401 gatcaatttg ctccttaaag cctatgcttt tatcgggatt tttggtcaaa atggctctat
    32461 taaccaattc ttggaattta tcggaattgg ttcacaacag ttgcttttta ccgatttttc
    32521 ctttatcttt gtcgcaagct acatcgagct cccctttatg attttgccga ttttcaatgt
    32581 cttagacgat atggataata atctcatcaa tgctagttat gaccttggtg caactaagtg
    32641 ggagaccttc cgtcatgtca tcttccctct atctatgaac ggtgtgcgaa gtggggttca
    32701 gtcggtcttt atcccaagtt tgagtctctt catgctgacc cgtttgattg gtgggaaccg
    32761 cgttatcacc ttggggacgg ctattgagca gaattttcta accaatgaca actatggtat
    32821 gggttcaacc atcggtgtga ttctcatcct gaccatgttc atcaccatgt gggtgactaa
    32881 ggaaaggaga gaacgatgaa aaaatttgcc aacctttatc tgggactggt ctttctggtc
    32941 ctctacctgc ctatctttta cttgattggc tatgccttta atgctggtga tgatatgaat
    33001 agctttacag gttttagctg gactcacttt gaaaccatgt ttggagatgg gagactcatg
    33061 ctgattttgg ctcagacatt tttcttggcc ttcctatcag ctttgatagc gaccattatc
    33121 gggacttttg gtgccattta catctaccag tctcgtaaga aataccaaga agcctttcta
    33181 tcactcaata atatcctcat ggttgcgcct gacgttatga ttggtgctag cttcttgatt
    33241 ctctttaccc aactcaagtt ttcacttggc tttttgaccg ttctatctag tcacgtggcc
    33301 ttctccattc ctatcgtggt cttgatggtc ttgcctcgac tcaaggaaat gaatggcgac
    33361 atgattcatg cggcctatga cttgggagct agtcaatttc agatgttcaa ggaaatcatg
    33421 cttccttacc tgactccgtc tatcattact ggttatttca tggccttcac ctattcgtta
    33481 gatgactttg ccgtgacctt ctttgtaaca ggaaatggct tttcaaccct atcagtcgag
    33541 atttactctc gtgctcgcaa ggggatttcc ttagaaatca atgccctgtc tgctctagtc
    33601 tttctcttta gtattatcct agttgtaggt tattacttta tctctcgtga gaaggaggag
    33661 caagcatgaa aaaaatctat tcatttttag caggaattgc agcgattatc cttgtcttgt
    33721 ggggaattgc gactcattta gatagtaaaa tcaatagtcg agatagtcaa aaattggtta
    33781 tctataactg gggagactat atcgatcctg aactcttgac tcagtttaca gaagaaacag
    33841 gaattcaagt tcagtacgag acttttgact ccaacgaagc catgtacact aagataaagc
    33901 agggtggaac gacctacgat attgccattc caagtgaata catgattaac aagatgaagg
    33961 acgaagacct cttggttccg cttgattatt caaaaattga aggaatcgaa aatatcggac
    34021 cagagtttct caaccagtcc tttgacccag gtaataaatt ctccatccct tacttctggg
    34081 gaaccttagg aattgtctac aacgaaacca tggtagatga agcgcctgag cattgggatg
    34141 acctttggaa gccggagtat aagaattcta tcatgctctt tgatggggcg cgtgaggtgc
    34201 tgggactagg actcaattcc ctcggctaca gtctcaactc caaggatctg cagcagttgg
    34261 aagagacagt ggataagctc tacaaactga ctccaaatat caaggctatc gttgcggacg
    34321 agatgaaggg ctatatgatt cagaataatg ttgcaatcgg cgtgaccttc tctggtgaag
    34381 ccagccaaat gttagaaaaa aatgaaaatc tacgttatgt ggtaccgaca gaggccagca
    34441 atctttggtt tgacaatatg gtcattccca aaacagttaa aaaccaaaac tcagcctatg
    34501 cctttatcaa ctttatgttg aaacctgaaa atgctctcca aaatgcggag tatgtcggct
    34561 attcaacacc aaacctacca gcgaaggaat tgctcccaga ggaaacaaag gaagataagg
    34621 ccttctatcc cgatgttgaa accatgaaac acctagaagt ttatgagaaa tttgaccata
    34681 aatggacagg gaaatatagc gacctcttcc tacagtttaa aatgtatcgg aagtaggaga
    34741 taaacgtaag aagacgaatc agtcaagctg gttcgttttt aaggaataga agtcagtttt
    34801 tagagcccta tctttttcta ttctagttgt ttatttgttt atttgcttat ttgcttattt
    34861 gcttgcctag tagtatacta agcctatact cttcaaacca cgtcagcgtt gccttgccgt
    34921 actcaagtac agcttgaggc tagcttccta gtttgctttt tgatttttat tgagtattaa
    34981 ccttacagaa agcggcaaca aataatgaaa atgtctactt ttttcaaaaa aagtttctgg
    35041 ccaaccttta tgattgttaa ccaaactgct atactattcc atttaaagga tggcttggat
    35101 cgacaatacc taacaactga gtccatatat tgggtgatag gcacctttat atttggaaat
    35161 attctagtag ctgtgtttag taatatgaaa atttgggata aaaagaaaaa cggcagtaag
    35221 aaaaaatata tcctgaaaaa gtaatcagag atgtagggaa ttggtctaat tcaacggaga
    35281 tcatttccag ttgacgcaag cttaaaaaaa cgttataata agaaagttga gaattgattt
    35341 tcacttgtct tagtccagag aaatggcggt gctgcgagcc atctaagcta ggaagtcatg
    35401 ctgctcaatc atacaattgc ataagaacaa gagaatgaca agttcattga atgaaggtgg
    35461 taccgcggtt tttcgccctt cgtgatatga gcttgtcttt tgatttttgg aggtgttgat
    35521 gaaaacattt cttgtcaaac aaaagtttcg tcttggaggc gaacgcttcg ctatcaagga
    35581 tgacagggga gaaattgcct atcaggtgga gggatcattt tttaagattc ctaaaacctt
    35641 taccatctat gatgcggctg gtgaacaagt cagtgagatt agtaaagaaa tcttgacctt
    35701 gcttcctcgt tttgagattc agcttcggga tggctcgagt tttgtcattc gtaagaagtt
    35761 gaccttctgg cgagataagt atgagtttga taatctaggt cttcgtatcg agggcaatat
    35821 ctgggatttg aatttcaaat tgctggatga tcgcgatcag ttgattgcgg aaattaagaa
    35881 ggaactcttc catctgacct ctacctatac cgtaacggtt cttgaagacg cttatgcaga
    35941 cctagtcatt tccctctgtg tcgcgattga ctatgtggaa atgctggaaa gccaatcata
    36001 ttaaacaagt aaataaggag acaatatgaa acaactatct agtgcacaag tacgccaaat
    36061 gtggcttgat ttctgggcga ccaaaggtca ctcagtagaa ccatcagtaa gtttggttcc
    36121 tgtaaatgac ccaactcttt tgtggatcaa ctctggggta gcaaccctta agaaatactt
    36181 tgacgggacc attatccctg aaaatccacg tattaccaat gcccaaaagg ctatccgtac
    36241 caacgacatc gaaaacgtag ggaagactgc gcgtcaccat accatgtttg aaatgttggg
    36301 gaacttctct atcggggatt acttccgtga cgaagctatc acttgggctt atgagctttt
    36361 gacaagccct gaatggtttg atttccctgc tgaaaaactt tacatgacct actatccaga
    36421 cgataaagat tcttacaacc gctggattga agtgggagtg gatccaagtc acttgattcc
    36481 aattgaggac aacttctggg aaatcggtgc gggaccttct ggaccagata cagaaatctt
    36541 ctttgaccgt ggggaagcct ttgacccaga aaatatcggt cttcgcctgc ttgcagaaga
    36601 tattgaaaac gaccgttata ttgaaatctg gaacatcgtt ttgtcacaat ttaacgcaga
    36661 ccctgctgtt cctcgtagcg aatacaagga attgccacat aagaacattg atacgggcgc
    36721 tggtttggag cgtttggtgg ctgttatcca aggggctaag accaactttg aaacggacct
    36781 ctttatgccg attatccgtg aagtcgagaa attgtctggt aaggtttatg accaagatgg
    36841 cgacaacatg agcttcaagg ttatcgcaga ccacattcgt tctctttcat ttgctatcgg
    36901 tgatggtgcc cttccaggaa atgaaggtcg tggttatgtt cttcgtcgtc ttctccgtcg
    36961 tgcttctatg catggtcaaa aattgggtat caacgagcct ttcctttaca aacttgttcc
    37021 aactgttgga aacatcatgg aaagctacta cccagaagtg cttgagaaac gtgactttat
    37081 tgagaaaatc gttaagagcg aagaagaatc atttgcccgt acccttcact caggtcaaca
    37141 ctttgcccaa ggcattgtgg cagacttgaa agaaaaaggt caatctgtca ttgctggtca
    37201 agatgtcttt aaactctatg atacatacgg attcccagtt gaattgactg aagaaattgc
    37261 tgaagaagct ggtatgactg tagaccgtga aggttttgaa gcagccatga aagaacagca
    37321 agaacgcgcg cgtgcgtcag ctgtcaaggg tggctcaatg ggtatgcaaa atgaaactct
    37381 tcaaaacatc actgtagaaa gtgtcttcaa ctacaatgct agccaattgt cttctaaatt
    37441 ggtagctatc gttgctgaca atgcagaagt aggagctgtt tcagaaggaa ctgcctctct
    37501 tatctttgcg gaaacgtcat tttatgctga aatgggtgga caggtagctg actacggaca
    37561 aatcttggat gagtcaggta aggttgtggc tactgtgacc aatgttcaga aagccccaaa
    37621 tggtcaagcc cttcatacag ttgaagtcct tgcaccgctt gccttgaacc aagaatatac
    37681 cttggcaatt gatagcaatc gccgtcaccg tgtcatgaaa aaccacactg cgactcattt
    37741 gcttcacgct gcccttcaca atatccttgg aaaccacgca acacaggcag gatctcttaa
    37801 cgaagttgaa ttccttcgct ttgactttac ccacttccaa gcagtaactg ctgaggaact
    37861 tcgtgcgatt gaacagcaag ttaacgagaa aatttgggaa gcacttgaag tgaagacagt
    37921 tgaaacggat attgacactg ctaaagaaat gggagctatg gccctctttg gtgagaaata
    37981 cggcaaggaa gttcgtgtcg tgactatcgg tgactactct attgaacttt gtggtggtac
    38041 tcatgttggc aacacttctg agattggtct cttcaaaatt gtcaaagaag aaggaatcgg
    38101 ttcaggaact cgccgtatct tggcagtgac tggtaaggaa gcctttgaag cctatcgtga
    38161 acaagaggat gctcttaaag ctgtcgcagc aaccttgaaa gcacctcaag tcaaggaagt
    38221 acctcacaag gtagaaggac ttcaagaaca acttcgtcaa cttcaaaaag aaaatgctga
    38281 gttgaaagaa aaagccgcag ctgcagccgc aggcgatatc ttcaaagatg ctaaggaagt
    38341 caacggtcat cgttacattg ctagtcaatt gtctgtatcc gatgccggtg cccttcgtac
    38401 ttttgcagat aactggaaac aaaaagacta ctctgatttt cttgtcctag ttgccgctat
    38461 cggtgacaaa gtcaatgtcc ttgtagcaag caagacaaaa gaccttcatg caggaaacct
    38521 tgtcaaagaa ttagcaccaa tcatcgatgg acgtggtggt ggtaaaccag acatggccat
    38581 ggcaggagga agaaaccaag ctaagatcca agaattgttg gatgcagtag caggtaaatt
    38641 gtaatcaagt aaagatctat ccatttgggt aggtcttttt gtgaatacaa aaaagccaaa
    38701 tccgcttgga cctagcttgg ttattatgag ctattagatg gtattgactg cccagacact
    38761 tacggatcta gctgagacag ggaattgtcc ataaccttcc tcatcaattg taacttgacc
    38821 ttggtggtta ccaagtaaat ctacaaaggt ttgattagtc cattcttgac cgacaaacat
    38881 tgacttgctg ttttcttggt catttgagat aaggactgcg attggggatt gattttcagc
    38941 acctgaacgt acccaaccga tacagttagc atggtcaaag tagtcatttt gttctccata
    39001 ggccaagtct tttcggatgg ctaggaggcg gtcaaggatt tctttgaaat cttcttgagc
    39061 atactggcct gaaatcccat agtagtctcc gtaaaagaca catggaaggc cgtcttggcg
    39121 taacaaaatg agggcatagg ctgctggctt gaaccattct tcaacggtag actcaagggc
    39181 ttgtcctcgt tgggtatcgt ggttgtcgat aaaagtcaca gccttgtcag gcttgagttc
    39241 aaccaggcta tctgtgaaaa tgccacgaag gtcatagttt gcgccagctt gactggcttc
    39301 aaagagattc tggtggagac gaacatcgac aaggtcaaag tgttcttccg ttttttcgag
    39361 atagtccaga ttggcttcct tgtctgggtt ccaaaattca ccaaaaacat agaaatcgtc
    39421 accgtatttt tccttcatat cgcggatgaa attgcgcata aagaaagagt caatatgctt
    39481 aacggcatcc aaacggaaac cagctacacc agtcgtttcc atgaaccaat cagcccagtc
    39541 atagatgttt tggatgactt caggatgttt aaagtctagg tcggcataca tgaggtagtc
    39601 gtagtttccg ttttcgttat cgaccaattc ctcgttagcc cagcccttgt tgtctccttg
    39661 gattaggtaa atcccggatt tacggcgttt ggcatcatag tctgtacctg tgaagtggta
    39721 ccagtgccag tggaagtcat tgtaggtatc ttggcgacca tcgaaggtaa aactagtcca
    39781 gccattgatg gtgaagggtt ctccaagttc aactgtacgg tctacaggat ccacttcaat
    39841 aacctgaaag gcttccctgt gatcagcagc agccttgtgg ttgagaacta catcggccat
    39901 aggttgaatt ccctgcgctt taagggcttg aatggcttga agatagtctt ctttgaaacc
    39961 atacttggtg cggacagtcc ctttttggtt gaactctcct aagtcaaata agtcatagac
    40021 cccatagccg acatcttttt cgttggttgc cttgaaggct ggtggcatcc agacgtgact
    40081 gatccccaga tgagctaggt gtggagcatt ttcagccaga cgcgtccagt gttgaccgtc
    40141 gtggggcaga taccattcaa agtattgcat gagtgtttga ttttgcatga tgtttcctct
    40201 tacttgtcaa tcttgttctt tattctatca taaagtatct ctcggagcaa acgtttgcgt
    40261 aagatagaag gaaactattt taactactta aaataaagta ttgatttttt tgtatcaaag
    40321 tgctagtata gcgatatata atacagataa agataggagt catcccatga ttgaatttca
    40381 aaatgttagt aagttgtatg gtgataaaga ggccttgagt aatctcaatt tgcagattga
    40441 aaatggagag attatgggct tgattggtca taatggggct ggaaaatcga ccaccataaa
    40501 atccctagtc agtatcattt cacccagcag tggtcgtatt ttggtagatg gtcaggagtt
    40561 atcggaaaat cgcttggcga tcaaacgaaa gattggctac gtagcagact cgcctgactt
    40621 atttttacgt ttaacggcca atgaattttg ggaattgatc gcctcatcct atgatctgac
    40681 tagctctgac ttggagacta gtctagctag gctattgaac gtttttgatt ttgctgaaaa
    40741 tcgttatcag gttattgaaa ccctttctca tggaatgcgt cagaaagttt ttgtcatcgg
    40801 ggcactcttg tctgatcctg atatttgggt cttggacgaa cccttgactg gtttggatcc
    40861 ccaggctgcc tttgatttga aacagatgat gaaggaacat gcacaaaaag ggaagacggt
    40921 cttgttttca actcatgtcc tagaggtagc cgagcaagtc tgtaatcgga ttgccatttt
    40981 gaaaaagggg catttgatct attgtggtag tgtagagaac ttgaggaaag accacccaga
    41041 ccagtctttg gaaagtatct accttagtct tgctggtaga aaagaggagg ttgcggatgc
    41101 gtctcaaggt cattaaaaaa ttagttgata tcaatatcct ctattcatct caagaagcta
    41161 atctggctaa tctacgaaag aagcaggcta agaatcctgg gaaaaaagta aatgtttccg
    41221 ctagagtcct aagttcttac attttttcta gtctcttgat gcttttcatg tttataaata
    41281 tagcctttcg ttttcctttt gaggaaatgc caagtttttt tagtacgatg gttgctattt
    41341 tactggtgct ggccttttca acttctttca ctgcatttta caatgtcttt tatgagagta
    41401 aggacctggc ctcctatagg ccctatgcct ttaaagaatc agagattata atggccaaag
    41461 gtctgtctgt cctcttgcca gctctagctg gaattgtacc aatcctagct tattttctgg
    41521 tcctctacat taggctagca ccttctctgt ggttgggttt gcctttgatg ctactgtcct
    41581 tgaccttatt atttgtctct gttactttag tgatggtagt ggcagtacat ttcttggctc
    41641 agactagggt cttcagaaag tatcggtcta ttttttcgaa tgtgatgatt gggataggag
    41701 ttctcatacc tttaatattt atcttctttc ttcagtcgac ttttggaagt attgttgaca
    41761 aagttagaga cattccattt ctcctttatc ctcttcatat cttttacaaa atagcagtgg
    41821 agcctttttc gacagaagcc ttagtgggtc tgctcgcttg gataggacta actctcttcc
    41881 tgctttatct gaccaaaaag aaggtccttc ctcgttttta tgacgtgatc ctgcttaata
    41941 gtgaggataa ggtcaaaaaa gaacgtcgca gcaaggagag aatttcaacc actaaaaagg
    42001 gattttttcg catggtttta cgctaccacc tcaccctctt gggacagggg actggcgtgg
    42061 ttacagtgct ttttacaagt gctttctttc cttatctcat gatgatcggt ctgatttcca
    42121 aaatccgaga ttctcagata gttccagaca ttcatcctcc atactggtta cccttgtttt
    42181 ttatagctct ctttatagca gttgtcaata acaatatcac cagcctgcat tcaattgcct
    42241 tgtccttgga gagggaaaat gttgattttc ttaagagttt accctttgac tttgctcgtt
    42301 atgtgaaagt gaaattttgg attatatatg ctgtccagtc ctttttacca gttctgactt
    42361 tgcttggtct ttctctatat ctaggcttgc ccatcatttc gatgatttac cttattgtgg
    42421 catggatcct tgccagtgtc atcctttctt gccaccatta ctttaaggac gttaaaaatc
    42481 tgtcaaccaa ttggagtagc attacggacc tggtgaatcg ttcaaatggc atagtcgcca
    42541 tagttttatt gtttatttat agtgcaatcc tgatggccct tgtaattggg agcatattct
    42601 tggttcagtc tctctccact atccttgcca tcagcttggg agtaggagct cttatcctcc
    42661 tgcttgctct tgctattttt ggctatcatt attacctgtc acgcatattg gcagaaatag
    42721 aaaaaagatg agctggttgg tcgcttgctt gataaattca attcgacaaa cgcttttata
    42781 gtttgttaga atgtagttgt aaatgattaa gattggtaat caaaaatata gggaggaatg
    42841 ttttgaataa gaaatataac atagttctat ttttgttgtt tatagtttat ttatttggat
    42901 atttttcaat ttcaaaaacg ttaattccta taatgtgtgt gttccaagta ttcttgatag
    42961 aacatatatt tagaattcga aatagaatga tgcagatagg tgaaattata attattgttg
    43021 cttctataat attatttatt gatagtatat tgagtttgta acaaaaggct tctctataaa
    43081 atcaaatttt ccagatatct actgaagctg atttatttct tcatctttct tctactacct
    43141 ttgtcactaa atttgacaga cacatattgc tgatacaacc tctctaccta taatctcaca
    43201 gttaacctga ggctagtttc atagtttgct atttgatttt cgttgataaa aaaaatgctc
    43261 ctccaagacg gaagagcatt ttttattgtg attcttacac atttacttcc tagttttgca
    43321 ggaagtctag tataccattt tttaaaagaa gagtaaaaaa gcaagggtag tttctttttt
    43381 gagaattgtc taaaagtttg atataatggt agttatgaat agaataagag tcagcaaaag
    43441 ggttgaaaag aagcttgcta aggggctagt tttactagaa gccagtgatc ttgagaatgt
    43501 caatcttaag gatcaggaag tagaggtgca gggtcaggaa ggaaactttc ttgggactgc
    43561 ctacctttct cagcaaaaca agggcttggg ctggtttgtc agcaaagaca aggtggcctt
    43621 caatcaagct ttctttgaaa cgttgtttag aaaagccaaa gaaaagagaa gcgcctacta
    43681 tcaagatgat ttaacaacta cctatcgtct ctttaatcaa gagggagatg gctttggggg
    43741 tctgacagtg gacctttatg gcaactacgc cgtcttttct tggtataact cttatgttta
    43801 tcagattcgt cagactatat cagaagcctt tagacaggtt ttccctgagg ttttaggggc
    43861 ttatgagaaa atccgcttta aaggtttgga ctatgaatct gcccatgttt atggtcaaga
    43921 agcacctgac tttttcactg ttttagaaaa tggtgtcctg tatcaagtct ttatgaatga
    43981 tggcttgatg acaggaattt tcctagacca gcatgaggtt cgcggtagtt tagttgacgg
    44041 cttgactatg ggtaaatcct tgctcaatat gttttcctac acagcggctt tttcagtagc
    44101 tgcggccatg ggaggagcta gccagacaac ttctgttgat ctagccaaac gttcacgaga
    44161 attgtctcaa gcgcattttc aggcaaatgg gctcagcaca gacgagcatc gttttatagt
    44221 catggatgtc tttgagtatt tcaaatatgc caaacgcaaa gacttgacct acgatgtgat
    44281 tgtcctagat ccgcctagct ttgctcggaa taaaaaacaa actttctctg tggccaagga
    44341 ttatcacaag ttgatttccc agagtcttga gattttaaat ccgggaggga ttatcattgc
    44401 cagtaccaat gctgccaatg tttcccgtca gaaatttaca gaacaaattg ataaaggctt
    44461 tgcaggaaga agttaccaga ttttaaacaa atatggtctt ccagcagatt ttgcctataa
    44521 taaaaaagat gaaagtagta attacctcaa ggtgattagt atgaaggtta gtaaatgaaa
    44581 ttaatcgttt cagtaatgcc aagaagttta gaggaggctc aggctctgga tgccacgagg
    44641 tacctggatg ccgacatcat tgaatggcgt gccgactatc tgcctaaaga agcgattttg
    44701 caggtagctc cagccatttt tgaaaaattc gcaggccgtg agttggtttt cacgctacga
    44761 actcgctccg aaggtggaga aatcgacctt tctccagaag agtatatcca tctaatcaag
    44821 gaagttgcgc aattctatca accagactat attgattttg agtactatag ctacaaggat
    44881 gtttttgagg aaatgctgga cttcccaaat cttgttttga gttaccataa tttccaagaa
    44941 acacctgaga acatgatgga aatcttgtca gagttgacga tcctaaatcc aaaacttgtt
    45001 aaggttgcgg tgatggctca cacggagcag gatgtcttag acttgatgaa ctatacacga
    45061 ggctttaaaa ccctcaatcc tgaacaggaa tatgtgacca tttctatggg taaggtgggc
    45121 aaggtctctc gtatcactgc ggatgtgacc ggttcgagtt ggtcttttgc cagtctggat
    45181 gaggttagtg cccctgggca gatttctcta gctagcatga aaaaaatcag ggagattttg
    45241 gatgaagctt gatggctata cacgtttagc tgcagttgtt gccaatccta ttaagcattc
    45301 tatttctccc ttcatccaca atagagcctt tgaggcgaca gctaccaacg gtgcttatgt
    45361 ggcttgggag attgaagcga gtgacttggc agaaacagtg gccaatattc gtcgctacca
    45421 gatgtttggc atcaatctgt ccatgcccta taaggagcag gtgattcctt atttggataa
    45481 gctgagcgat gaagcgcgct tgattggtgc ggttaatacg gttgtcaatg agaatggcaa
    45541 tttaattgga tataatacag atggcaaggg attttttaag tgcttgcctt cttttacaat
    45601 ttcaggtaaa aagatgaccc tgctgggtgc aggtggtgcg gctaaatcaa tcttggcaca
    45661 ggctattttg gatggcgtca gtcagatttc ggtctttgtt cgttccgttt ctatggaaaa
    45721 aacaagacct tacctagaca agttacagga gcagacaggt tttaaagtgg atttgtgtgc
    45781 tttagagtat gtttctgaac tgcaagcaag gattgccgag tcggatttgc tagttaatgc
    45841 caccagtgtg ggcatggatg gccaatcctc tcctgttcct gaaaacatag tcttaccaga
    45901 aactctctta gttgcagata tcatatacca accctttgaa acaccgtttt tgaaatgggc
    45961 tagaagtcag ggcaatccag cagtcaatgg tctgggaatg ttgctctatc aagctgcaga
    46021 agcttttcaa ctgtggacag gcaaggaaat gccgacagaa gagatttggc agtctttaac
    46081 agaaaaatac caataaagaa agggagactc tcctatgaaa atcagaatcg atattcctca
    46141 tcatccttat gatattcaga ttgaaaaagg ttgtatggcc caggctggtc agtggttgcg
    46201 agaactctgg caaccgcaaa aggtagtcat tgtgacagat aaccatgtag cctctctcta
    46261 tgcagagaag gtcaagctca gcctagaaga tgctggtttt caggtagctg tttttgattt
    46321 cttagaaggt gaagaaagaa agaatttaac tactgttcag aaagtctatg aatttctagt
    46381 caagcaaggt ctgactcgta gcgatggaat cgttgctctt ggtggtggcg ttgttgggga
    46441 cctggctgga tttgtagcct ctacctatat gcggggtatt cactttgttc agattccgac
    46501 tagtttgaca gctcaggttg attcttctat cggtggaaag acaggcgtta acacaccatt
    46561 tgctaaaaat atggtgggga cctttgccca accagatggg gttctgattg atccacttgt
    46621 tcttgaaacc ctcggaaaaa gagagttgat tgaagggatg ggtgaagtta tcaagtatgg
    46681 cttgattgag gatccagaac tgtgggctct cttgacgggg ctgaatggtt ctgttgagag
    46741 cattttggaa catgcagaga ccttgattga acattcttgt caggtgaagc gcaagatggt
    46801 ggttgaagat gagttggaca atggtattcg tctttacctc aattttggcc acactattgg
    46861 ccatgccatc gaagcgactg ccggttatgg caaggtcatg catggagagg ctgttgccat
    46921 gggaatggta cagatttcca agattgctga ggaaaaaggc ctcatgccag ctggcattac
    46981 ccaatctatc acagagatgt gtcagaaatt cggcttgcct gttgactatg aaaattggga
    47041 agttgacaag ctttatcagg ctcttactca tgacaagaaa gcgcgtggta acaccttgaa
    47101 attggtcttg gtgccagagc ttggttcagc gaccattcat ccagtttctc tggaagagat
    47161 gaaagactac ttggtaaaat aaggagagtg tatgagatat ttaactgcag gagaatcaca
    47221 cggcccccgt ctaacagcta ttattgaggg aattccagct ggacttccat tgacagctga
    47281 ggatatcaat gaggacctta gacgccgtca gggtggctac ggtcgtggtg gtcgtatgaa
    47341 gattgagagt gaccaggttg tctttacttc gggcgttcgc cacgggaaga cgacaggggc
    47401 gcctattact atggatgtca tcaataagga ccaccagaaa tggctggaca tcatgtctgc
    47461 ggaggacatt gaagaccgcc ttaaaagcaa gcggaaaatt actcatcctc gcccaggtca
    47521 tgccgatttg gttgggggga ttaagtaccg ttttgatgat ttgcgaaatt ctttggagcg
    47581 ttcatcagct cgtgaaacca ccatgcgggt ggcagttggt gcagtagcca aacgtctctt
    47641 ggctgagctg gatatggaga ttgccaacca tgtcgtggtc tttggtggca aggaaatcga
    47701 tgttcctgaa aatctgacag tcgctgaaat taagcaaaga gctgcccagt ctgaagtttc
    47761 tattgtcaac caagaacgag aacaggaaat caaggactat attgaccaaa tcaaacgtga
    47821 tggtgatacc atcggtgggg ttgtggagac agtcgtcgga ggcgttccag ttggtcttgg
    47881 ttcctatgtc caatgggata gaaaattgga tgcaagattg gctcaagctg ttgtctctat
    47941 caatgccttt aaaggggtgg aatttggtct tggctttgag gctggttatc gtaaaggcag
    48001 ccaagttatg gatgaaattc tctggtctaa agaagacggt tatactcgcc gtaccaataa
    48061 tctaggtggt tttgaaggtg gtatgactaa tgggcaaccc atcgttgttc gtggggttat
    48121 gaaacccatt cctactcttt ataaacctct tatgagtgtg gatatcgaaa cccacgaacc
    48181 ttacaaggca accgtggaga gaagtgatcc gactgctctt ccagctgcag gaatggtcat
    48241 ggaagcagtt gtagcaacgg ttctggcgca agaaatcctc gaaaaattct catcagataa
    48301 tcttgaggaa ctaaaagaag cggtagccaa acaccgagac tatacaaaga actattaagg
    48361 agttcctatg gcaaaaacaa tctatatcgc aggtcttggg ttgattggag cctctatggc
    48421 acttggtatc aaacgcgatc atccagatta tgaaatttta ggttataatc gtagtcaagc
    48481 ttcgagagac atcgccttga aagaaggcat gattgaccgt gcaacggatg attttgctag
    48541 ttttgctcct ttggcagatg tcattatcct cagcttgcca atcaaacaaa ctattgcttt
    48601 cattaaggag ttggccaatt tggatttgcg agaaggcgtt attatttcag atgctggttc
    48661 gaccaagtca accattgtgg atgcggcgga gcagtatttg gctggcaagt ctgttcgctt
    48721 tgtcggggcc catcccatgg ctggtagtca caagacaggg gctgcttcgg cagatgtcaa
    48781 tctttttgaa aatgcctatt atatctttac accttcaagc ctgacaagtc aggacacgct
    48841 taaggaaatg aaggatctgc tttcaggtct tcatgctcgt tttatcgaga ttgatgccaa
    48901 ggagcatgat cgtgtcactt ctcagattag ccattttcct catattttgg cttctagtct
    48961 catggagcag actgcggtct atgctcaaga gcatgagatg gcaaggcgct ttgcggcagg
    49021 tggttttcga gatatgaccc gaattgcgga aagcgagcca ggaatgtgga cctccattct
    49081 cttgtccaat agcgagacca ttctggatag aattgaggat ttcaaggaac gtttggaagc
    49141 gattggtcag gccattagta agggagatga agagcaaatt tggaactttt ttaaccaagc
    49201 gcgtgaacaa cgccagacca tggaaatcca taagcgtggt ggtgtggata gctcttacga
    49261 cctctatgtt gacgttcctg atgaagaaga tgtcatcctg cggattttgg aactgctacg
    49321 tgggacttcc ttggttaaca tccacatcaa cgaggaaaat cgtgaggata ttcacggaat
    49381 cctacaaatt tcatttaaaa atgctcaaga cttggaaaga gccgagcatc tcataacaaa
    49441 aaataccgac tatacagtcg tcattaaata aggagaagaa catgtcaaat atttacgata
    49501 gtgcaaacga actcagtcgc ggtctacgcg gattaccaga atacaaggct gttaaagcag
    49561 ctaaagatgc gattgcagca gatgctgagg caagcaaaat ctttacagaa tatcttgcct
    49621 ttcaagagga aattcaaaaa ctagcacaga caggtcaaat gccagatgcg tccttccaag
    49681 ctaagatgga aggctttggt aaacagattc aaggaaatag cctcttgtca gaattcttta
    49741 ccaagcaaca acaattggcc atttaccttt ctgacattga aaaaattgtt ttcgaaccag
    49801 tttcagaatt gctgaaataa gaaaagaact atcctaaagt caggaatttt taaggaattt
    49861 ctggcttttt atgataaaat aggtaaaagt attgcaagta tgaggtccag tatgaaacta
    49921 aaaacaaaca ttcgccattt acatggtagt atccgcgtcc caggtgacaa gtctatcagc
    49981 caccgttcca ttatctttgg aagtttggct gagggtgaga ccaaggttta tgatattctg
    50041 cgaggtgaag acgttctttc gaccatgcag gtttttcgtg accttggtgt tgaaattgag
    50101 gataaagatg gggttattac cgttcaaggt gtaggcatgg ctggcttaaa agcgccgcaa
    50161 aatgccctta atatgggaaa ttctggcacc tcgattcgcc tgatttcagg tgtccttgct
    50221 ggtgcagatt tcgaagtaga gatgtttgga gatgatagtc tttccaaacg tcctatggac
    50281 cgtgtgaccc ttccactgaa aaaaatgggc gtcagcatct cagggcaaac tgaacgagac
    50341 ttgcctcccc ttcgcttaaa agggacgaaa aacctaagac ctattcatta tgagttgcca
    50401 attgcctctg cccaagtcaa gtcagccttg atgtttgcag ccttacaagc taagggggag
    50461 tcagttatta tcgaaaaaga gtacacccgt aatcatactg aagatatgtt gcaacaattt
    50521 ggtggtcatt taagtgtgga tggtaagaaa atcacagtcc aagggccaca aaaattgaca
    50581 ggacagaagg tggtcgtacc aggagatatt tccagtgcag ccttttggtt agtcgcaggt
    50641 ttgattgctc caaattctcg tctagtgctg cagaatgtgg ggataaacga aactcgcacc
    50701 ggtattattg atgtcattcg tgccatgggt ggaaaattgg aaataactga aatcgatcca
    50761 gtcgctaaat ctgcaacctt gattgttgag tcttctgact tgaaaggaac agagatttgt
    50821 ggcgctttga ttccacgttt gattgatgaa ttgcctatta ttgccctact tgcgacccaa
    50881 gcccaaggtg taacagttat caaggatgct gaggagctca aggtcaagga aacagaccgt
    50941 attcaggttg tggcagacgc cttaaatagt atgggagcag atattactcc tacggcagat
    51001 gggatgatta tcaaaggaaa atcagctctt cacggtgcta gagtcaatac gtttggtgac
    51061 caccgtatcg gcatgatgac agctatcgca gccctattgg ttgcagatgg agaggtggag
    51121 cttgaccgtg cagaagccat caataccagc tatcctagtt tctttgatga tttggagagc
    51181 ttgattcatg gctaaggtgt tattagggtt tatgggggct ggaaaatcga ctattgcaag
    51241 aggcttggac cctaattacc ttgatatgga tgctctgatt gagaagcgcc taggtatgtc
    51301 cattgcgaat tttttcgctg aaaagggaga agcagccttt cgtcaggtag aatcagaagt
    51361 cctagctgat ttattacaaa gagaccaagt cgtgtcaact ggaggaggag tggttatttc
    51421 tcagagaaat cgtgacttac tcaagactaa tacagataac atctacctga aagcagattt
    51481 tgaaaccctc tacctacgta tcgcagctga taaggacaat cagcgaccgc tttttctaaa
    51541 taatagcaag gaagaactag tagctatttt tcaagaaaga caggcttggt atgaggaagt
    51601 ggctagtcgg gttttggatg tgaccaagct aagcccagag gaaattatag aggaactaag
    51661 atgaaaattg cttatctagg tcccaaagga tcattttcac accacgttgt gcagacagct
    51721 tttcctcatg aggaattgca ggcttttgcc aacattacag atgtcatcaa ggcttatgag
    51781 caaggattag tggactattc tgtggtgcca gttgaaaatt ctattgaggg tagtgttcat
    51841 gaaaccttgg actatctttt tcatcaggct cacatccaag cagtagcaga aatcgttcag
    51901 cctattcatc agcagttgat ggtggttcca ggccatacta agattgaaaa gattttttca
    51961 catccacagg ccttggctca aggaaagaaa ttcatcgatg aacaatatcc agaggctcaa
    52021 atcgaggtaa cagctagtac agcttatgcg gcccgtttta tttccgaaca tccagatcag
    52081 ccctttgcag caattgcacc tagaagttct gctgaagaat atggattgga actgattgcc
    52141 gaggatattc aggaaatgga agccaatttc acacgtttct ggcttctagg agctgaaaag
    52201 cctagtattc ccttgcaagc acaaactgaa aagatgagtt tggccttgac attacctgac
    52261 aaccttccag gtgcacttta taaggccctg tcgacctttg cttggcgagg aattgacttg
    52321 acaaaaattg aaagtcgtcc actcaagaca gcactgggtg aatacttttt cattatcgat
    52381 gtggattata ccgataagga cttggtccac tttgcccaaa aagaattaga agcgattgga
    52441 atccagtata aaattctggg tgcctatcct atttatccaa tatcagacca tggaaaggag
    52501 agaagatgag taaagaaaat cccttaagtc atcatgagca gttgcgttat gattatttgc
    52561 taaaaaatat tcactatctc aatgagagag aaaaaaatga gtttgtctat ttgcaagaaa
    52621 agctaactct tgctagggga aatagtagct ctagcttgga acaagaaaga gaagagcagg
    52681 ttgacttacc aagctatgcg aaccggagtc gctcacaatc caaatcacaa gcactctctt
    52741 tccctccaaa aaagaaaaga cggaagctcc gtcttaaacg aatttttatg gtgatttttt
    52801 cacttttggt ctgtgtggct ttggccatgg tattcatgtt tttgcgtggt taccaagatg
    52861 ctagcgcaaa gaaaactgct gatgcccggg cagctcaagt agaagtcttt aatggtcagg
    52921 acactagaga tggagttaat attttaatca tgggtactga tggtcgaatc ggccagaaca
    52981 gtgttgagac acgaactgac tctattatgg tattaaatgt cgggggctca gataagaaaa
    53041 tgaagctagt cagtttcatg cgtgataatt tggtctatat agatggttat agtcaagtga
    53101 ttaacggtag aaaacagaca gataacaagt taaacgtagc ctacgagtta ggagaacaag
    53161 aagggcaaaa aggggcagaa atggttcgcc aagtcttgaa agataatttt gacttggaca
    53221 ttaagtacta cgccttggtt gatttccagg cctttgccac agcgattgac acgcttttcc
    53281 ctgatggggt gacgattgat gctcaatttt caacattgaa tgggcgtccc ctaacagaag
    53341 ctacagtcgg agatgattta tacgctaccg agactgagtc tccaacccaa accattaaag
    53401 tcggaaaaca gcagatgaat ggctcgaccc tgctcaatta tgctcgtttc cgtgatgatg
    53461 atgaggcgga ttacggccgt acaaaaagac agcaacaagt tttaacagca attttagagc
    53521 aaattaaaga tcccactaaa cttttcactg gttctgaagc tcttggaaag gtttttgcta
    53581 tgacctcaac caacgtaccc tatactttcc tcctaacaaa cggtttatct gttttggatg
    53641 gagcaaaaaa tggtattgaa aaattgacga ttccagaact gggtgactgg gtagatgcct
    53701 atgatgttta tggaggcttg ggcttgctgg ttgatcaaaa caaatatcaa accaagctcg
    53761 ctcaaatggg cttgagataa gataatactc aatgaaaatc aaagtgcaaa ttaggaagct
    53821 agccgcaggc tgctaaaaac acagttttga ggttgtagat aagactgacg aagtcagtta
    53881 cctataccta cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaga
    53941 cagaaaaatc aaagtttgat agctatttgg atagcagtca ggctttgatt ttttacagtc
    54001 tgcaatagat tttcacccct tgtttgtggt ataatgaaac gatacgatag aaagaataat
    54061 gaacaatatg actgatttaa aagcaattca ggctcgtagt ctggagatgg ctgaatattt
    54121 tgtggccttt tgtaaagaac atgatttgct ctgttatctc tgtggcggag gcgctattgg
    54181 tacccttcga aacaagggat ttattccttg ggacgacgac ctagactttt ttatgcctcg
    54241 taaagattat gagaaattag cagaattatg gcctcgttat gcagatgaac gttatttctt
    54301 gtcaaagagt cacaaggatt ttgttgatcg taatcttttt attaccattc gtgacaagaa
    54361 aaccacctgt atcaagcctt atcagcagga tttggatttg ccacatggtc tggccttgga
    54421 tgttttgcct ttggattatt atccgaaaaa tccagctgag cggaaaaaac aggttcgttg
    54481 ggccttgatt tattcactct tttgtgcgca aactattcca gaaaagcatg gtgctctcat
    54541 gaaatgggga agtcgcattt tactgggttt gactccaaaa tctctccgtt atcgcatctg
    54601 gaaaaaagct gagaaagaaa tgactaagta tgatttggct gattgtgatg gcattacaga
    54661 attatgctca ggtcctggct acatgagaaa caagtaccca atcacatctt ttgaagacaa
    54721 tcttttcttt ccatttgaag gaacagagat gcctattcca atcggctatg atgtctatct
    54781 cagaactgct tttggggatt atatgacgcc tccaccagca gacaagcagg taccgcatca
    54841 tgatgctgtc atcgctgata tggataagtc ttatacagaa tacaagggag aatatggtgg
    54901 ctaagaaaaa aatcttattt tttatgtggt ctttttctct tggaggtggt gcagagaaga
    54961 ttctatcaac cattgtttca aatctggatc cagaaaagta tgatattgat attcttgaaa
    55021 tggagcactt tgacaaggga tatgaatctg ttccaaagca tgtacgcatt ttaaaatccc
    55081 ttcaagatta tcgccaaacc agatggttac gagctttttt gtggagaatg agaatttatt
    55141 ttccaagact ggctcgtcgt ttgcttgtaa aagatgatta tgatgttgaa gtttctttta
    55201 ccattatgaa tccaccactg ttgttctcta aaagaagaga agtcaagaag atatcttgga
    55261 ttcatggaag tattgaagaa cttcttaagg atagctctaa aagagaatca catagaagcc
    55321 agttggatgc tgcgaataca attgtaggga tttcaaaaaa gaccagcaat tctatcaagg
    55381 aagtttatcc agattatgct tctaaattac agacaatcta caatggatat gattttcaga
    55441 ctattctaga aaaatctcaa gagaagatcg atatcgagat tgctcctcaa agtatctgta
    55501 ctatcggacg gatcgaggaa aataagggtt ctgaccgtgt agtggaagtg atacgattat
    55561 tacaccaaga gggaaaaaac tatcatctct attttatcgg ggctggtgat atggaagagg
    55621 aactgaaaaa acgagtcaaa gagtatggga ttgaggacta tgtacatttc cttggttatc
    55681 aaaaaaatcc ttatcagtat ttatctcaga cgaaagttct cttgtctatg tctaaacaag
    55741 aaggttttcc tggagtgtat gtggaggcct tgagtctggg actccctttt atctctacgg
    55801 acgttggagg ggctgaggaa ttatcccaag aaggacgatt tggacaaatc attgagagca
    55861 atcaagaggc agctcaggcg attactaatt acatgacttc tgcctcaaac tttgatgtcg
    55921 atgaggctag ccaattcatt caacaattta caattacaaa acaaatcgaa caagtagaaa
    55981 aactattaga ggagtagcat ggaaactgca ttaattagtg tgattgtgcc agtctataat
    56041 gtggcgcagt acctagaaaa atcgatagct tccattcaga agcagaccta tcaaaatctg
    56101 gaaattattc ttgttgatga tggtgcaaca gatgaaagtg gtcgcttgtg tgattcaatc
    56161 gctgaacaag atgccagggt gtcagtgctt cataaaaaga acgaaggatt gtcgcaagca
    56221 cgaaatgatg ggatgaagca ggctcacggg gattatctga tttttattga ctcagatgat
    56281 tatatccatc cagaaatgat tcagagctta tatgagcaat tagttcaaga agatgcggat
    56341 gtttcgagct gtggtgtcat gaatgtctat gctaatgatg aaagcccaca gtcagccaat
    56401 caggatgact attttgtctg tgattctcaa acatttctaa aggaatacct cataggtgaa
    56461 aaaatacctg ggacgatttg caataagcta atcaagagac agattgcaac tgacctatcc
    56521 tttcctaagg ggttgattta cgaagatgcc tattaccatt ttgatttaat caagttggcc
    56581 aagaagtatg tggttaatac taaaccctat tattactatt tccatagagg ggatagtatt
    56641 acgaccaaac cctatgcaga gaaggattta gcctatattg atatctacca aaagttttat
    56701 aatgaagttg tgaaaaacta tcctgacttg aaagaggtcg cttttttcag attggcctat
    56761 gcccacttct ttattctgga taagatgttg ctagatgatc agtataaaca gtttgaagcc
    56821 tattctcaga ttcatcgttt tttaaaaggc catgcctttg ctatttctag gaatccaatt
    56881 ttccgtaagg ggagaagaat tagtgctttg gctctattca taaatatttc cttatatcga
    56941 ttcttattac tgaaaaatat tgaaaaatct aaaaaattac attagaacgg gggtgaccaa
    57001 gtgattgatg ggaaacgatt attatttagt ttgaccatag tcagttatgc cttgacgcta
    57061 gtaagtggaa ttgtgtatct gtttaataat aataatgtta gcttactttc tactttattg
    57121 ttcttgttgg ttagtagctt aattgcttgt tggaatgata tcaagtatta cttaatccat
    57181 tttattttct atttaaccat ttttgtattt ctggtatcaa gaccgaccat tgattatttt
    57241 agggatggtg ctttggatac ctatcatcca atagcctatc gttttgcctt tatagttgtc
    57301 atggtttcga ttctgggctt gaccacagga ggcattctgg ctcgctactt catagctagg
    57361 aagaaaataa aagtagcaaa tataggaaat tctctaaaag aggtttatat caagcggtta
    57421 cgctttgtat cactaggagt ttttcttcta acctatcctt tctatttcat tcgattattt
    57481 gaacggctct tgtatcgttt gcagacttcc tactatgcct actatgcaaa ttttgaaagt
    57541 aaactgcctt attttaccta cattttgtct acctttacgg tctatgcaat gtgtatgtat
    57601 ctggcaacca agccaaagaa attgcaggcc acagcagtgc ttgtctcctt tattgcagct
    57661 aatactattc atttggcaat tgggacacga aatcccttta ttttaagtat tttatttgct
    57721 tttgtttatt actttatgcg ggagcaaact gaaaaaggaa aatggattgg gtttaaagaa
    57781 aagttagcga tttttgtagg ttctcctatt ctcatgttag cgatgggagt actcaattat
    57841 gtacgggata atgtccaagt ttcccataca ggtttctggg atatcttact tgactttatc
    57901 tataaacaag ggactagttt tggtgttctg gctcgaggtt ttctatttaa cagtagcctc
    57961 ccttaccgag atttccgtaa ttttactttt ggtcctgttc ttgattattt tgcaaggggg
    58021 agtttgggag ctattttcgg aggaaaagcc tttgaacata caaccaatag tgtggaacta
    58081 gctattgata gtaatagtta tgcccacaat ctatcctatc ttgtcttgaa caaggaatac
    58141 ctgaaagggc atggtatcgg aagtagttat atcatggagt tgtataccga ctatggtatg
    58201 attggagtct ttctgcttag tttcttactc ggcgtattat ttatagccat gctgcaagta
    58261 gcctatcgct caaggacaat cctatttgct ttatccctac tcatcttgaa taatctattc
    58321 tttatgccaa gaagcagctt ttcagaaagt ttcttcaatt tatttacaat gcaattctgg
    58381 ggaattgttc ttgtgattat atttgtagca aaaatgctta caaaggaaaa ctagtattta
    58441 ctaaacaaag gagaaaaaaa tcatgtttga acattattca gtagctgatt tgtttgcaaa
    58501 tctttataaa aaacgaaaag caaatatttt agctctcatc gctttatttg ctctcattgc
    58561 tgtaccattt acaattaaag cagttaggaa taaaaacact gtcaaagata caacaagtta
    58621 ttcaacttat cttatctata aaatcactcc tccagaagag tcggccaaaa cgattttgaa
    58681 tcatcaaatt ggtggttata gtgattttta tgggaaattg attgatggta atttgaatgg
    58741 agcttatctt ttcaatgatg tagaacccag tgagttgaaa aaaattgcca gtgaattaga
    58801 cacgacagaa acaaccttga aaaattcaac gaatgactat tggtggaaaa aattgaccgt
    58861 ctactatatg attgacgatg caggggttgg tgtgaaaatt ttgacatcaa gtaaagatgc
    58921 caatgacttg ttagagaaaa aaattgatgg gttgattgag aaatttaaac atgcttatgc
    58981 aaatgtgaaa attgaaaaac tggaaaccat caactctaaa gaattgaacg caaatggtga
    59041 aacagcgctt ggcttaaatg tgaaaaatct gattcttcgt ttagttgtta ttggagtggt
    59101 ttgtgtgatt ttggttgtga tgggaaatgt gttagtttat ctctttaatc caacaatcaa
    59161 tagagtaggt gatttttctc agtatcaaat tgattttgta acagagatta caacaattgc
    59221 taacctagca gatgttttgt catacaaaaa tactggacag gaattgacca tcgttagctc
    59281 aaataaagct atcctagata aattgaaaca gagtcaagaa gctttaaaag gaatgcattt
    59341 tgtagattta caggatgtat catctctttt ggaaagagat acagtccttc ttgttgaaga
    59401 gtacggagtg actcgttata agaaatttga gcaaagtctt caaattctca gaaacttaaa
    59461 tcgttctatc ctcggtgtag caacctttaa attataagta ttctgatgta taaggtcttc
    59521 aaaatcggct cttagccgat tttgaaggct ttttctatct gtctgcagaa attttctttt
    59581 ggagtctcct atagaaagac cctagggaaa atctatccgt atagaggagc cttcttttga
    59641 taaaatcgta aaaatctagt ataatagata gaactgaaag tatgaggtta ctagcaatga
    59701 aaatgaaaca aattagtgat acaactttaa aaatcacgat gtctttagag gatttgatgg
    59761 atcgtggaat ggagattgct gactttctcg ttcctcaaga aaaaacagaa gagttctttt
    59821 atgctatctt ggatgagcta gagatgcctg atagctttct ggatacaggc atgttgagct
    59881 tccgtgtgac tccaaaacct gataaggtag atgtctttgt gaccaagtca aagattgacc
    59941 aaaatctaga ttttgaagac ttatcggatt tgccagatat ggaagaattg gctcaaatgt
    60001 ctccagatga atttatcaaa accctggaaa aaagcatcgc agacaaaacc aaggatgata
    60061 tcgaagccat tcaatctctt gagcaagttg aagccaagga agaagagcaa gagcaagctg
    60121 aacaagaagc tgagagtaag aaagaacctt acatctacta catcctttct tttgctaagt
    60181 tggctgactt ggtagctttt gccaagacag tgacttttga aatggaaact tctgaactct
    60241 acaaaatgaa cgagcgctat tatttgacca ttttagtgga tattgaaaat catccaagcc
    60301 catatccagc ttggctgttg gcccgtatgc gcgagtttgc agacgatagt gatatcagtc
    60361 gctcagtctt acaagagtat ggtcaagtct tgatgagtca cgatgcagtg ctcaatctgc
    60421 aaaaaatcgg ctaatccttt ctggaaagct attttcagat tttaagaaga gcgaatcgtc
    60481 tgattcgttt tttcttttta tactgaaata gtgatttact ataataggaa ttttcacaaa
    60541 attctgttat aatggctata ttagaaaatt tcgaggagat aaagatgaca gttaaaattg
    60601 ctttactggg atttggtacc gttgcaagtg gtgtgccttt cctcctaaag gaaaatggag
    60661 gaaaaatcaa tcaatcagca cattcagata tcaaagttgc taaggtattg gtcaaggatg
    60721 aagatgaaaa aaatcgcttg cttgcagcag ggaatgactt taactttgta accaatgtgg
    60781 atgatatttt atcagaccag gatgttacta tcgtagtgga attgatgggg cgtattgagc
    60841 ctgctaaaac ctttatcact cgtgccttgg aagctggaaa acacgttgtt actgctaaca
    60901 aggacctttt agctgtccat ggcgcagaat tgctagaaat cgctcaagct aacaaggtag
    60961 cactttacta cgaagcagca gttgctggtg ggattccaat tcttcgtact ttagcaaatt
    61021 ccttggcttc tgataaaatt acgcgcgtgc ttggagtagt caacggaact tccaacttca
    61081 tggtgaccaa gatggtggaa gaaggctggt cttacgatga tgctcttgcg gaagcacaac
    61141 gtctaggatt tgcagaaagc gatccgacga atgacgtaga tgggattgat gcagcctaca
    61201 agatggttat tttgagccaa tttgcctttg gcatgaagat tgcctttgat gatgtagccc
    61261 acaagggaat ccgcaatatc acaccagaag acgtagctgt agctcaagag cttggttacg
    61321 tagtgaaatt ggttggttct attgaggaaa cttcttcagg tattgctgca gaagtgactc
    61381 caaccttcct acctaaagcg cacccacttg ctagtgtgaa tggcgtaatg aacgctgtct
    61441 ttgtagaatc tatcggtatt ggtgagtcta tgtactacgg accaggtgcg ggtcaaaaac
    61501 caactgcaac aagtgttgta gctgatattg tccgtatcgt tcgtcgtttg aatgatggta
    61561 ccattggcaa agacttcaac gaatatagcc gtgacttggt cttggcaaat cctgaagatg
    61621 tcaaagcaaa ctactatttc tcaatcttgg ctctagactc aaaaggtcag gtcttgaagt
    61681 tggctgaaat cttcaatgct caagatattt cctttaagca aatccttcaa gatggcaaag
    61741 agggtgacaa ggcgcgtgtc gttatcatca cacacaagat taataaagcc cagcttgaaa
    61801 atgtctcagc tgaattgaag aaggtttcag aattcgacct cttgaatacc ttcaaggtgc
    61861 taggagaata agatgaagat tattgtacct gcaaccagtg ccaatatcgg gccaggtttt
    61921 gactcggtcg gtgtagctgt aaccaagtat cttcaaattg aggtctgcga agaacgagat
    61981 gagtggctga ttgaacacca gattggcaaa tggattccac atgatgagcg taatctcttg
    62041 ctcaaaatcg ctttacaaat tgtaccagac ttgcaaccaa gacgcttgaa aatgaccagt
    62101 gatgtccctt tggcgcgcgg tttgggttct tccagctcgg ttattgttgc tgggattgaa
    62161 ctagccaacc aactgggtca actcaactta tcagaccatg aaaaattgca gttagcgacc
    62221 aagattgaag ggcatcctga caatgtggct ccagccattt atggtaatct cgttattgca
    62281 agttctgttg aagggcaagt ctctgctatc gtagcagact ttccagagtg tgattttcta
    62341 gcttacattc caaactatga attacgtact cgcgacagcc gtagtgtctt gcctaaaaaa
    62401 ttgtcttata aggaagctgt tgctgcaagt tctatcgcca atgtagcggt tgctgccttg
    62461 ttggcaggag acatggtgac cgctgggcaa gcaatcgagg gagacctctt ccatgagcgt
    62521 tatcgtcagg acttggtaag agaatttgcg atgattaagc aagtgaccaa agaaaatggg
    62581 gcctatgcaa cctacctttc tggtgctggg ccgacagtta tggttctggc ttctcatgac
    62641 aagatgccaa caattaaggc agaattggaa aagcaacctt tcaaaggaaa actgcatgac
    62701 ttgagagttg atacccaagg tgtccgtgta gaagcaaaat aaagaataga agataggatg
    62761 gggaaactct tgaccagagg gtttcatatc ctttttgtga aaagaagttt atactcaatg
    62821 aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaagcactg ctttgaggtt
    62881 gtagataaga ctgacgaagt cagctcaaaa cagtgttttg aggttgcaga tagaactgac
    62941 gaagtcagta acatatatac ggtaaggtga cgctgacgtg gtttgaagag attttcgaag
    63001 agtattagtt aaaaacgtga taaaggagaa ataaaaatgg cagaaattta tctagcaggt
    63061 ggttgttttt ggggcctaga ggaatatttt tcacgcattt ctggagtgct agaaaccagt
    63121 gttggctacg ctaatggtca agtcgaaacg accaattacc agttgctcaa ggaaacagac
    63181 catgcagaaa cggtccaagt gatttacgat gagaaggaag tgtcactcag agagatttta
    63241 ctttattatt tccgagttat cgatcctcta tctatcaatc aacaagggaa tgaccgtggt
    63301 cgccaatatc gaactgggat ttattatcag gatgaagcag atttgccagc tatctacaca
    63361 gtggtgcagg agcaggaacg catgctgggt cgaaagattg cagtagaagt ggagcaatta
    63421 cgccactaca ttctggctga agactaccac caagactatc tcaggaagaa tccttcaggt
    63481 tactgtcata tcgatgtgac cgatgctgat aagccattga ttgatgcagc aaactatgaa
    63541 aagcctagtc aagaggtgtt gaaggccagt ctatctgaag agtcttatcg tgtcacacaa
    63601 gaagctgcta cagaggctcc atttaccaat gcctatgacc aaacctttga agaggggatt
    63661 tatgtagata ttacgacagg tgagccactc ttttttgcca aggataagtt tgcttcaggt
    63721 tgtggttggc caagttttag ccgtccgatt tccaaagagt tgattcatta ttacaaggat
    63781 ctgagccatg gaatggagcg aattgaagtt cgttctcgtt caggcagtgc tcacttgggt
    63841 catgttttca cagatggacc gcgggagtta ggcggcctcc gttactgtat caattctgct
    63901 tctttacgct ttgtggccaa ggatgagatg gaaaaagcag gatatggcta tctattgcct
    63961 tacttaaaca aataaaacag agagtggggc ttcccacttt cttcatttct agaatatgaa
    64021 tagaagggat ttatgaaaca cctattatct tacttcaaac cctacatcaa ggaatcaatt
    64081 ttagccccct tgttcaagct gttagaagct gtttttgagc tcttggttcc catggtgatt
    64141 gctgggattg ttgaccaatc tttacctcag ggagatcaag gtcatctctg gatgcagatt
    64201 ggtctgctcc ttatctttgc agtaattggc gttttagtgg ccttgatagc tcaattttac
    64261 tcagcaaagg cagcagtagg ttttgctaag gaattgacaa acgatcttta tcgtcatatt
    64321 ctttccttgc ccaaggacag cagagaccgt ctgacaactt ctagtttggt cactcgcttg
    64381 acttcggata cctaccagat tcagactggt atcaatcaat tcctgcgtct ctttttacga
    64441 gcgcccatta tcgtttttgg tgccattttt atggcttatc gaatctcagc tgagttgact
    64501 ttctggttct tagtcatggt tgccattttg accattgtca ttgtagggtt atctcgattg
    64561 gtcaatcctc tctacagtag tctcagaaag aaaacggacc aactggttca ggaaacgcgc
    64621 cagcaattgc aagggacgcg ggttattcgt gcttttggtc aagaaaaacg agagttacag
    64681 atttttcaaa cccttaacca agtttatgct agattacaag aaaagacagg tttctggtct
    64741 agtttattaa cacctctgac ctatctgatt gtcaatggaa ctcttctcgt tattatctgg
    64801 caaggctata tttcaattca aggaggagtg ctcagtcaag gtgctctcat tgctcttatc
    64861 aattacctct tacagatttt ggtggaattg gtcaagcttg ccatgctgat cacttccctc
    64921 aaccagtcct acatctcagc caagagaatc gaggaggtct ttgcggaatc tcccgaaaac
    64981 atccattcag aattagaaca aaagcaagtt accagtgatc gggttttaca agtccaagaa
    65041 ttgaccttta cctatcctga tgcggcccag ccttctctga gagacatttc ctttgatatg
    65101 actcaaggac aaatccttgg tatcattggg gggactggtt ctggtaaatc aagcttggtg
    65161 caactcttac ttggacttta tccagtagac aaggggaaca ttgaccttta tcaaaatgga
    65221 cgtagtcctc ttaatttgga gcagtggcgg tcttggattg cctatgtacc tcaaaaggtc
    65281 gaactcttta aaggaaccat tcgttccaac ttgactctag gtttcaatca agaagtatct
    65341 gaccaggaac tctggcaggc cttggagatt gcgcaagcta aggattttgt cagtgaaaag
    65401 gaaggactct tggatgctct agttgaggca ggggggcgaa atttctcagg tggacaaaaa
    65461 caaagattgt ctatcgcccg agcagtcttg cgccaagctc cgtttctcat cctagatgat
    65521 gcaacctcgg cactggatac cattacagag tccaagctct tgaaagctat tagagaaaat
    65581 tttccaaaca cgagcttaat tttgatctct caacgaacct caactttaca gatggcggac
    65641 cagattctcc tcttggaaaa aggtgagttg ctagctgttg gcaagcacga tgacttgatg
    65701 aaatccagcc aagtctattg tgaaatcaat gcatcccaac atggaaagga ggactagaat
    65761 gaaacgacaa actgtaaacc agacgctcaa acgtttagtc gtagatttag caagccatcc
    65821 tttcctcctt ttcctagcct ttctaggaac tattgctcaa gttggcttat caatttacct
    65881 acctattctg attgggcagg tcattgacca agtcctagtg gctggttcat caccagtttt
    65941 ttggcagatt tttctccaga tgctcttggt ggtaatagga aatactctgg tacaatgggc
    66001 caatcctctc ctctataatc gtctaatctt ctcttatacc agagatttac gggagcgaat
    66061 catccataag ctccatcgtt taccgattgc ctttgtagat aggcaaggta gtggagagat
    66121 ggttagtcgt gtaaccacgg acatcgaaca gttggcagct ggcttgacca tgatttttaa
    66181 ccaatttttc attggtgttt tgatgatttt ggtcagtatt ctagccatgc tccaaattca
    66241 tctcctcatg actctcttag tcttgctgtt gacgccactg tccatggtga tttcacgctt
    66301 tattgccaag aaatcctatc atctcttcca gaagcaaaca gagacgaggg gaattcagac
    66361 tcagttgatt gaagaatcgc ttagtcagca gactataatc cagtccttca atgctcaaac
    66421 agaatttatc caaagattgc gtgaggctca tgacaactac tcaggctatt ctcagtcagc
    66481 catcttttat tcttcaacgg tcaatccttc gactcgcttt gtaaatgcac tcatttatgc
    66541 ccttttagct ggagtaggag cttatcgtat catgatgggt tcagccttga ccgtcggtcg
    66601 tttagtgact tttttgaact atgttcagca atacaccaag ccctttaacg atatttcttc
    66661 agtgctagct gagttgcaaa gtgctctggc ttgcgtagag cgtatctatg gagtcttaga
    66721 tagccctgaa gtggctgaaa caggtaagga agtcttgacc agtgaccaag ttaagggagc
    66781 tatttccttt aaacatgtct cttttggcta ccatcctgaa aaaattttga ttaaggactt
    66841 gtctatcgat attccagctg gtagtaagat agccatcgtt ggtccgacag gtgctggaaa
    66901 atcaactctt atcaatctcc ttatgcgttt ttatcccatt agctcgggag atatcttgct
    66961 ggatgggcaa tccatttatg attatacacg agcatcattg agacagcagt ttggcatggt
    67021 gcttcaagaa acctggctca cacaagggac cattcatgat aatattgcct ttggcaatcc
    67081 tgaagccagt cgagagcaag taattgctgc tgccaaagca gctaatgcag actttttcat
    67141 ccaacagttt ccacagggat acgataccaa gttggaaaat gctggagaat ctctctctgt
    67201 cggccaagct cagctcttga ccatagcccg agtctttctg gctattccaa agattcttat
    67261 cttagacgag gcaacttctt ccattgatac acggacagaa gtgctggtac aggatgcctt
    67321 tgcaaaactc atgaagggcc gcacaagctt catcattgct caccgtttgt caaccattca
    67381 ggatgcggat ttaattcttg tcttagtaga tggtgatatt gttgaatatg gtaaccatca
    67441 agaactcatg gatagaaagg gtaagtatta ccaaatgcaa aaagctgcgg cttttagttc
    67501 tgaataagcc attctctttt gaaagtttat ggacgaaaaa agttgccttc gagtgacttt
    67561 tttgttacaa tagctagaaa aattgttcac tgtaatactc aatgaaaatc aaagagcaaa
    67621 ctaggaagct agccgtaggt tgctcaaagc acagctttga ggttgtagat aagactgacg
    67681 aagt
//
LOCUS       DAVHSH010000006        58620 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000006 DAVHSH010000000
VERSION     DAVHSH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.006"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            251..727
                     /locus_tag="VVR08_000481"
     CDS             251..727
                     /locus_tag="VVR08_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6074448.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            765..1070
                     /locus_tag="VVR08_000482"
     CDS             765..1070
                     /locus_tag="VVR08_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6074449.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIESAIKEHELS"
     gene            1118..2593
                     /locus_tag="VVR08_000483"
     CDS             1118..2593
                     /locus_tag="VVR08_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6074450.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2619..2696
                     /locus_tag="VVR08_000484"
                     /pseudo
     CDS             2619..2696
                     /locus_tag="VVR08_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2943..9644
                     /locus_tag="VVR08_000485"
     CDS             2943..9644
                     /locus_tag="VVR08_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU6074451.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TQKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEETFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESADGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9901..10749)
                     /locus_tag="VVR08_000486"
                     /pseudo
     CDS             complement(9901..10749)
                     /locus_tag="VVR08_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10960..11319)
                     /locus_tag="VVR08_000487"
     CDS             complement(10960..11319)
                     /locus_tag="VVR08_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU6074452.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            11411..12367
                     /locus_tag="VVR08_000488"
                     /pseudo
     CDS             11411..12367
                     /locus_tag="VVR08_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            12351..12908
                     /locus_tag="VVR08_000489"
     CDS             12351..12908
                     /locus_tag="VVR08_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6074453.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALKKTQERLHQAGLTNAQLILQGHETLDQFVTKTKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCHLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12901..13155
                     /locus_tag="VVR08_000490"
     CDS             12901..13155
                     /locus_tag="VVR08_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074454.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            13167..15221
                     /locus_tag="VVR08_000491"
     CDS             13167..15221
                     /locus_tag="VVR08_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU6074455.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIVLTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            15400..16260
                     /locus_tag="VVR08_000492"
     CDS             15400..16260
                     /locus_tag="VVR08_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU6074456.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            16471..17181
                     /gene="ccdA2"
                     /locus_tag="VVR08_000493"
     CDS             16471..17181
                     /gene="ccdA2"
                     /locus_tag="VVR08_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6074457.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            17201..17767
                     /locus_tag="VVR08_000494"
     CDS             17201..17767
                     /locus_tag="VVR08_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU6074458.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17778..18890
                     /gene="msrB"
                     /locus_tag="VVR08_000495"
     CDS             17778..18890
                     /gene="msrB"
                     /locus_tag="VVR08_000495"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6074459.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            19158..19895
                     /locus_tag="VVR08_000496"
     CDS             19158..19895
                     /locus_tag="VVR08_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074460.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            19892..21583
                     /locus_tag="VVR08_000497"
     CDS             19892..21583
                     /locus_tag="VVR08_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6074461.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            21699..22262
                     /locus_tag="VVR08_000498"
     CDS             21699..22262
                     /locus_tag="VVR08_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU6074462.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            22284..27896
                     /locus_tag="VVR08_000499"
     CDS             22284..27896
                     /locus_tag="VVR08_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6074463.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESSKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEVVPDDTKYVDEEV
                     VERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKGTKPVEGTAVETR
                     EEVIPFATKEQEDDTLKRGTRQVAQEGVNGKKQITETYKTIRGEKTNEAPTVEETVLQ
                     APQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVEIKSIKVALKDNT
                     GTVIKEVTVEENNLNATLDNLKYYQGYTLSTTMVYNRGEGEETEMLEDKEVQLDLKKV
                     EIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKTTRLAVSSVEEVV
                     VDGKTLYKVVAKAPDLVQRREDDTLSEEYVHYFEKQLPKVDNVYYSFNELITDMQKNP
                     TGTFKLGADLNAANTPTPSKSYVTGEFKGKLSSVDGQHYTIHNTARPLFNNIVGGTVK
                     NINLNNVNIDMPWADQIASVANVIKGGSLIENVKVKGNVLGRNWVSGFIDKIDSGGRL
                     VNVAFIGNVTSVGDGDKFLTGIVGENWKGYVEKAYVEANIKGKRAKAAGISYWSQNSG
                     DNNAVGRDGAIKKSVVKGSIDVEKPIEVGGAVGSLNYLGYIEDTVAMMKVKNGEIFYG
                     SHDIDTDPYYTGERVNRNFIVDGVSEGKSSYTYSKQQKRIKSISQEEADKKIKELGIT
                     ADKFTIIDPIVNKLNNIKQKADTYKDTQDYKVDRELAYRNIEKLQPFYNKEWIVDQGN
                     KVPSNSKLLTTEVLSVTGMKDGQFVTDLSEIDKIMIHYADGTKEEKSVSPKPTSNVEQ
                     VKEYGITDLGDVVYTPNMVVKDRAQLLSDVKAKLDTITLESPEVRAITGNVGALYLEE
                     SFAEVKGNLDKLVKALVENEDHQLNSDEAAIKAFLKKVEDNKAKIMMALTYLNRYYGI
                     EYGDLNIKNIMMFKPDFYGKTPSVIDRLIRIGSQEKNLKGDRTQDAYREIIAGDTGKG
                     DLRSFLDYNMRLFTNDTDLNDWFIHSAKNVYVVEPETTNPDFKNKRHRVFDGLNNNMH
                     ARMILPLLNLKKAHIFMISTYNTMAYSSFEKYGKNTEAEREAFKERINYVAKAQQTYL
                     DFWSRLALTNVRDRLLKSQNMVPTPVWDNQAYAGIKDANRRGYGTDGKVATPIRELFG
                     PTDRWHQINWNMGAMAKVYGKPYEDEQVFFMVTNMLEDFGISAFTHETTHINDRMAYL
                     GGHGHRPGTYLEAYAQGMLQTPDKSTSNGEYGALGINMAYHRQNDGNQWYNPDPDKLQ
                     SREQIDHYMKNYNDALMMLDHLEADAVLPQLNGNTSRWFKKMDRQYRSGNSGHQFDKI
                     RELTEDEKKVAINTIDDLITNNLITKHGAPGDGTYNPTDFRSAYVNMNMMTGIYGGNT
                     STGAPGAASFKHNTFRMWGYFGYENGFVGYASSKYQNAANKENNRMLGDDFIIKKVSN
                     GRFTNLEDWKKEYYKEVKAKGEKGFTAIEIDGKQITNYAELKVLFDKAVEADLAGGGT
                     AKTVELKSKVFKALLKNSDGFTGNLFKA"
     gene            27970..29691
                     /gene="pabB"
                     /locus_tag="VVR08_000500"
     CDS             27970..29691
                     /gene="pabB"
                     /locus_tag="VVR08_000500"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU6074464.1"
                     /translation="MHRKTVIDFRALGERHIFTQPIKELKTRDLTEVTALLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            29692..30309
                     /locus_tag="VVR08_000501"
     CDS             29692..30309
                     /locus_tag="VVR08_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6074465.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGSHVLNKAKPKEFVEKTRSFLELLK"
     gene            30359..31349
                     /locus_tag="VVR08_000502"
                     /pseudo
     CDS             30359..31349
                     /locus_tag="VVR08_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            31484..32443
                     /locus_tag="VVR08_000503"
     CDS             31484..32443
                     /locus_tag="VVR08_000503"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU6074466.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            32540..33379
                     /locus_tag="VVR08_000504"
     CDS             32540..33379
                     /locus_tag="VVR08_000504"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU6074467.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLFKQLEANPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(33427..33597)
                     /locus_tag="VVR08_000505"
     CDS             complement(33427..33597)
                     /locus_tag="VVR08_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU6074468.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33718..34602
                     /gene="miaA"
                     /locus_tag="VVR08_000506"
     CDS             33718..34602
                     /gene="miaA"
                     /locus_tag="VVR08_000506"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU6074469.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            34595..35833
                     /gene="hflX"
                     /locus_tag="VVR08_000507"
     CDS             34595..35833
                     /gene="hflX"
                     /locus_tag="VVR08_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU6074470.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            35826..36449
                     /locus_tag="VVR08_000508"
     CDS             35826..36449
                     /locus_tag="VVR08_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU6074471.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            36464..37393
                     /locus_tag="VVR08_000509"
     CDS             36464..37393
                     /locus_tag="VVR08_000509"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU6074472.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAKKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            37414..38169
                     /locus_tag="VVR08_000510"
     CDS             37414..38169
                     /locus_tag="VVR08_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6074473.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(38223..39131)
                     /locus_tag="VVR08_000511"
     CDS             complement(38223..39131)
                     /locus_tag="VVR08_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6074474.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            39195..39464
                     /locus_tag="VVR08_000512"
     CDS             39195..39464
                     /locus_tag="VVR08_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU6074475.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39464..39844
                     /locus_tag="VVR08_000513"
     CDS             39464..39844
                     /locus_tag="VVR08_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6074476.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            39933..40160
                     /locus_tag="VVR08_000514"
     CDS             39933..40160
                     /locus_tag="VVR08_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074477.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(40200..40925)
                     /locus_tag="VVR08_000515"
     CDS             complement(40200..40925)
                     /locus_tag="VVR08_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6074478.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGIKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            41087..42928
                     /gene="typA"
                     /locus_tag="VVR08_000516"
     CDS             41087..42928
                     /gene="typA"
                     /locus_tag="VVR08_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU6074479.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42948..43202
                     /locus_tag="VVR08_000517"
     CDS             42948..43202
                     /locus_tag="VVR08_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU6074480.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            43565..43864
                     /locus_tag="VVR08_000518"
     CDS             43565..43864
                     /locus_tag="VVR08_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6074481.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSVVSKWDSHSDKGSAPAGKTSEAWIWTKFGEQVSFYYDYD"
     gene            43935..45956
                     /locus_tag="VVR08_000519"
     CDS             43935..45956
                     /locus_tag="VVR08_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6074482.1"
                     /translation="MKKLFILLSTFFLSFFFAWIIVLRAPQYLYASYDSVTLLRVKKE
                     AQEPTREVFEQELEKFVNSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKQFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKAIADRKTPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWHDRVDYYQISFGL
                     GDRVNDTENQNKWYEFSKEAVEKEQALFVKENLIHFANPQGKNENGETLDTYSPDANV
                     LYVSPSYLDKENVAVNDETRQKLAHLQKGEFGLLLPESLRSQEAELKKVFEERLNYYG
                     KSSEDKDAPLEYEMRAIVSYLPTGQKRFVYNNGESPVSIQYLTDPILVVFTPTSTGDS
                     FISKYVWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILSSRDLVIGLLTLFVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            45958..46599
                     /locus_tag="VVR08_000520"
     CDS             45958..46599
                     /locus_tag="VVR08_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074483.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKSSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            46703..48055
                     /locus_tag="VVR08_000521"
     CDS             46703..48055
                     /locus_tag="VVR08_000521"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU6074484.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            48059..49117
                     /locus_tag="VVR08_000522"
     CDS             48059..49117
                     /locus_tag="VVR08_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU6074485.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            49127..50326
                     /gene="divIB"
                     /locus_tag="VVR08_000523"
     CDS             49127..50326
                     /gene="divIB"
                     /locus_tag="VVR08_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU6074486.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            50559..51260
                     /gene="pyrF"
                     /locus_tag="VVR08_000524"
     CDS             50559..51260
                     /gene="pyrF"
                     /locus_tag="VVR08_000524"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU6074487.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            51294..51926
                     /locus_tag="VVR08_000525"
     CDS             51294..51926
                     /locus_tag="VVR08_000525"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU6074488.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMNLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            52106..52509
                     /locus_tag="VVR08_000526"
                     /pseudo
     CDS             52106..52509
                     /locus_tag="VVR08_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52605..53369
                     /locus_tag="VVR08_000527"
     CDS             52605..53369
                     /locus_tag="VVR08_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074489.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGAYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVTYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            53369..54120
                     /locus_tag="VVR08_000528"
                     /pseudo
     CDS             53369..54120
                     /locus_tag="VVR08_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            54130..54828
                     /locus_tag="VVR08_000529"
     CDS             54130..54828
                     /locus_tag="VVR08_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074490.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            54825..55472
                     /locus_tag="VVR08_000530"
     CDS             54825..55472
                     /locus_tag="VVR08_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074491.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(55552..56418)
                     /locus_tag="VVR08_000531"
                     /pseudo
     CDS             complement(55552..56418)
                     /locus_tag="VVR08_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(56430..57188)
                     /locus_tag="VVR08_000532"
                     /pseudo
     CDS             complement(56430..57188)
                     /locus_tag="VVR08_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(57189..57476)
                     /locus_tag="VVR08_000533"
     CDS             complement(57189..57476)
                     /locus_tag="VVR08_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6074492.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            complement(57486..57866)
                     /locus_tag="VVR08_000534"
     CDS             complement(57486..57866)
                     /locus_tag="VVR08_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU6074493.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(57826..58506)
                     /locus_tag="VVR08_000535"
     CDS             complement(57826..58506)
                     /locus_tag="VVR08_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6074494.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
BASE COUNT        17992 a        10639 c        12889 g        17100 t
ORIGIN      
        1 ttatctacaa cctcaaaact gtgttttgag taacctgcgg ctagcttcct agtttgctct
       61 ttgattttca ttgagtatta gaacagaaaa atgcttggag tatttgtttg tgtgtttatt
      121 tttatataac aaactataaa caaaacaaaa atataaaaaa agagacaaaa aagaacaaaa
      181 agtaattgac aacggtttca tatagtgtta tacttatggc ataaagttaa tggaaagaag
      241 ggaaaacctt atggtattag attatttctt tgacaaaaac cttgtgtttt gcttagaagc
      301 ggataatcaa gaacaactct ttgatcaggt tgcaacttta ttggaagaac gagaaattgt
      361 cactccaact tatcgtgaag ccttgatcac gcgtgaaaag tcatttccaa ctggtttaga
      421 tatggaattt ctaggaaagg acttgccaaa tgtagcgatt cctcatacag atattgttca
      481 taatctagct gagaaagtgg tggttgttcg attagaaaaa ccagtaactt ttcacaatat
      541 gatagctcct gataaggaag tagaagtatc cctactcttc tttattatta acaattcaag
      601 ttcaagtcaa acaaatattc tggctcagtt gatggacttt ttcacaggaa atggacatct
      661 tgaagattta tcaaaaattt ccgaaccaga aaaactttat gcttacattg ctgaagcaac
      721 cgcttaatct tgtctattaa aaaataaaat cggaggaaat ccaaatgatt aaaattcttg
      781 ctgcctgcgg tgcaggtgtt aactcaagtc accaaattaa aagtgctcta gaagaagaac
      841 tttcaaaccg tggttatgat gttcactgtg atgcagtcat ggtgaaagat gtaaacgaag
      901 accttatgaa aggttacgat atctttacac caatcgctgc aacagacctt ggttttgaac
      961 caggtatccc agttatcgaa gctgggccaa tcttattccg tatcccagca atgagtgctc
     1021 cagtatttga caatattgaa tcagctatta aagaacacga attaagctaa ttctaatttg
     1081 ttaacattca tataacataa aaaagggagg aactgttatg gatgcaatct ttgacctaat
     1141 cggaaaggtt ttcaatccca tcttagaaat gggtggacct gtcatcatgt taatcatttt
     1201 gacagtattg gctttacttt ttggagtgaa attctccaaa gcgcttgaag gtggtatcaa
     1261 acttgccatc gctcttacag gtatcggtgc tatcatcggt atgctaaatg gtgctttctc
     1321 agcatcactt gcaaaattcg ttgaaaacac tggtatccaa ttgagtatta ccgacgttgg
     1381 ttgggcacca ctcgcaacaa tcacttgggg ttctgcttgg acactatact tcttgctcat
     1441 catgttgatt gtcaacgtag tgatgcttgc tatgaagaaa accgatacac ttgatgtcga
     1501 tatctttgat atctggcact tgtctatcac aggtctcttg attaaatggt atgctgataa
     1561 caatggtgtg agtcaagggg tttcactctt tattgctaca gcagctatcg tccttgtcgg
     1621 tgtgttgaaa attatcaact ctgacttgat gaaacctaca tttgatgacc ttcttaacgc
     1681 cccaagttca tcaccaatga catcaactca catgaactac atgatgaacc cagttatcat
     1741 ggttttggat aagatttttg aaaaattctt cccaggcctt gataaatatg actttgatgc
     1801 tgctaaattg aacaagaaaa tcggtttctg gggatctaaa ttcttcatcg gtttcatcct
     1861 tggtatcgtt atcggtatta tgggaactcc acatccaatt gcaggtgttg cagatgcaga
     1921 taaatggcgt cttgttatca aaggatggtt gtctcttggt ttgactgccg gtgtatcttt
     1981 ggaactcttc tcacttatcg gttcatggtt catcgcagcc gtagaaccac tatcacaagg
     2041 tattacaaac gttgctacta aacgtcttca aggacgtaaa ttcaatatcg gtcttgactg
     2101 gccattcatc gctggtcgtg ctgaaatctg ggcttgtgcc aacgtacttg caccaatcat
     2161 gttgattgaa gcagtgcttc tttcaaaagt tggaaatggt atcttgccac ttgcaggtat
     2221 catcgctatg ggtgttactc cagctctctt ggttgtaact cgtggtaaat tgctccgtat
     2281 gattatcttc ggaacactct tgttgccact cttccttctt tcaggtaccc ttattgcacc
     2341 atttgcaaca gaacttgcta aaggtgtagg tgccttccca gaaggtgtga gccaaactca
     2401 attgattact cactctactc ttgaaggacc aatcgaaaaa cttcttggtt ggacaattgg
     2461 taacactaca actggtgata tcaaagcaat ccttggtgca gtagtcttcc ttgtattcta
     2521 tatcggtatc tttgcttggt acagaaaaca aatgatcaaa cgtaacgaag agtacgcagc
     2581 aaaagcaaaa taatgcgctc ctataaaata taaactcaat gaaaatcaaa gagcaaacta
     2641 ggaagctagc cgcaggttgc tcaaaacaca gttttgaggt tgtagataag actgacgaag
     2701 tcagctcaaa acacagtttt gaggttgtag atgaaactga cgaagtcagc tcaaaacatg
     2761 gttttgaggt tgtagatgaa actgacgaag tcagtaatca tatctatggc aaggcgacac
     2821 tgacgaagtt tgaattggat tttcgcagag tgtaaattgt tgaaactagg ttgtcatacc
     2881 atgtatacca cttgggtttt ggcagtagct aactgcacta aatataatat aaggagggtt
     2941 ttatggggaa aggtcattgg aatcggaaaa gagtttatag cattcgtaag tttgctgtgg
     3001 gagcttgctc agtaatgatt gggacttgtg cagttctatt aggaggaaat atagctggag
     3061 aatctgtagt ttatgcggat gaaacactta ttactcatac tgctgagaaa cctaaagagg
     3121 aaaaaatgat agtagaagaa aaggctgata aagctttgga aactaaaaat gtagttgaaa
     3181 ggacagaaca aagtgaacct agttcaactg aggctattgc atctgagaag aaagaagatg
     3241 aagccgtaac tcaaaaagag gaaaaagtgt ctgctaaacc ggaagaaaaa gctccaagga
     3301 tagaatcaca agcttcaagt caagaaaaac cgctcaagga agatgctaaa gctgtaacaa
     3361 atgaagaagt gaatcaaatg attgaagaca ggaaagtgga ttttaatcaa aattggtact
     3421 ttaaactcaa tgcaaattct aaggaagcca ttaaacctga tgcagacgta tctacgtgga
     3481 aaaaattaga tttaccgtat gactggagta tctttaacga tttcgatcat gaatctcctg
     3541 cacaaaatga aggtggacag ctcaacggtg gggaagcttg gtatcgcaag actttcaaac
     3601 tagatgaaaa agacctcaag aaaaatgttc gccttacttt tgatggtgtc tacatggatt
     3661 ctcaagttta tgtcaatggt cagttagtgg ggcattatcc aaatggttat aaccagttct
     3721 catacgatat caccaaatac cttcacaaag atggtcgtga gaatgtgatt gctgtccatg
     3781 cagtcaacaa acagccaagt agccgttggt attcaggaag tggtatctat cgtgatgtga
     3841 ctttacaagt gacagataag gtgcatgttg agaaaaatgg gacaactatt ttaacaccaa
     3901 aacttgaaga acaacaacat ggcaaggttg aaactcatgt gaccagcaaa atcgtcaata
     3961 cggacgacaa agaccatgaa cttgtagccg aatatcaaat cgttgaacga ggtggtcatg
     4021 ctgtaacagg cttagttcgt acagcgagtc gtaccttaaa agcacatgaa tcaacaagcc
     4081 tagatgcgat tttagaagtt gaaagaccaa aactctggac cgttttaaat gacaaacctg
     4141 ccttgtacga attgattacg cgtgtttacc gtgacggtca attggttgat gctaagaagg
     4201 atttgtttgg ttaccgttac tatcactgga ctccaaatga aggtttctct ttgaatggtg
     4261 aacgtattaa attccatgga gtatccttgc accacgacca tggggcgctt ggagcagaag
     4321 aaaattataa agcagaatac cgtcgtctca aacaaatgaa ggagatggga gttaactcca
     4381 tccgtacaac ccacaaccct gctagtgagc aaaccttgca aatcgcagca gaactaggtt
     4441 tactcgttca ggaagagacc tttgatactt ggtatggtgg caagaaacct tatgactatg
     4501 gacgtttctt tgaaaaagat gccactcacc cagaagctcg aaaaggtgaa aaatggtctg
     4561 attttgacct acgtaccatg gtcgaaagag gcaaaaacaa ccctgctatc ttcatgtggt
     4621 caattggtaa tgaaataggt gaagctaatg gtgatgccca ctctttagca actgttaaac
     4681 gtttggtcaa ggttatcaag gatgttgata agactcgcta tgttaccatg ggagcagata
     4741 aattccgttt cggtaatggt agcggagggc atgagaaaat tgctgatgaa ctcgatgctg
     4801 ttggatttaa ctattctgaa gataattaca aagcccttag agctaagcat ccaaaatggt
     4861 tgatttacgg ttcagaaaca tcatcagcaa cccgtacacg aggaagttac tatcgccctg
     4921 aacgtgaatt gaaacatagc aatggacctg agcgtaatta tgaacagtct gactatggga
     4981 atgatcgtgt gggttggggg aaaacagcaa ccgcttcatg gacttttgac cgtgacaacg
     5041 ctggctatgc tggacagttt atctggacag gtacggacta tattggtgaa cctacaccat
     5101 ggcacaacca aaatcaaact cctgttaaga gctcttactt tggtatcgta gatacagccg
     5161 gcattccaaa acatgacttc tatctctacc aaagccaatg ggtttctgtt aagaagaaac
     5221 cgatggtaca ccttcttcct cactggaact gggaaaacaa agaattagca tccaaagtag
     5281 ctgactcaga aggtaagatt ccagttcgtg cttattcgaa tgcttctagt gtagaattat
     5341 tcttgaatgg aaaatctctt ggtcttaaga ctttcaataa aaaacaaacc agcgatgggc
     5401 ggacttacca agaaggtgca aatgctaatg aactttatct tgaatggaaa gttgcctatc
     5461 aaccgggtac cttggaagca attgctcgtg atgaatctgg caaggaaatt gctcgagata
     5521 agattacgac tgctggtaag ccagcggcag ttcgtcttat taaggaagac catgcgattg
     5581 cagcagatgg aaaagacttg acttacatct actatgaaat tgttgacagc caggggaatg
     5641 tggttccaac tgctaataat ctggttcgct tccaattgca tggccaaggt caactggtcg
     5701 gtgtagataa cggagaacaa gccagccgtg aacgctataa ggcgcaagca gatggttctt
     5761 ggattcgtaa agcatttaat ggtaaaggtg ttgccattgt caaatcaact gaacaagcag
     5821 ggaaattcac cctgactgcc cactctgatc tcttgaaatc gaaccaagtc actgtcttta
     5881 ctggtaaaaa agaaggacaa gagaagactg ttttggggac agaagtagca agagttcgta
     5941 cattaattgg taaagaacca aaaatgccga aaacagtagg ttttgtatac agcgatggta
     6001 gtcgtgaaaa acttccagta acttggtctc aagtcgatgt tagtcaagca ggagttgtga
     6061 ctgttaaagg tacagcaaat ggacgtgagg tagaggctca tgtcgaggtt ctagcaattg
     6121 cgaaagaatt accaacagtt aaacgtattg ctccaaatac tgacttgaat tctgtagaca
     6181 aatctgtttc ttatgttttg actgatggaa gtgtacaaga gtacgaagta gatagctggg
     6241 agattacgga agtagataaa gccaaacttt cagtagctgg atcacgtatt caaatgactg
     6301 gtcagttagc tggagaaact attcatgcaa cccttgtggt agaagaagga aatgctgcag
     6361 cacctgtagt gccaactgtt actgttggag gtgaagcagt aacaggtctt actagtcgac
     6421 aaccaatgca atatcgtact ctatcttatg gtgcccaatt gccagaagtc acagcaagtg
     6481 ctgaaaatgc tgatgtgaca gttcttcaag caagcgcagc aaacggcatg cgtgcaagca
     6541 tatttgttca gcctaaagat ggtggccctc ttcaaaccta tgcaattcaa ttcctagaag
     6601 aagcaccaaa aattgctcac ttgagcttgc aagtggaaaa agctgacagt ctcaaagaag
     6661 accaaactgt caaattgtcg gttcgagctc actatcaaga tggaacgcaa gctgtattac
     6721 cagctgataa agtaaccttc tctacaagtg gtgaagggga agtcgcaatt cgtaaaggaa
     6781 tgcttgagtt gcataagcca ggagcagtca ctctgaacgc tgaatatgag ggagctaaag
     6841 gccaagttga actcactatc caagccaata ctgagaagaa gattgcgcaa tccatccgtc
     6901 ctgtaaatgt agtgacagat ttgcatcagg aaccaagtct tccagcaaca gtaacagttg
     6961 agtatgacaa aggtttccct aaaactcata aagtcacttg gcaagctatt ccgaaagaaa
     7021 aactagactc ctatcaaaca tttgaagtac taggtaaagt tgaaggaatt gaccttgaag
     7081 cgcgtgcaaa agtctctgta gaaggtatcg tttcagttga agaagtcagt gtgacaactc
     7141 caatcgcaga agcaccacaa ttaccagaaa gcgttcggac atatgattca aatggtcacg
     7201 tttcatcagc taaggttgca tgggatgcga ttcgtccaga gcaatacgct aaggaaggtg
     7261 tctttacagt taatggtcgc ttagaaggta cgcaattaac aactaaactt catgttcgcg
     7321 tatctgctca aactgagcaa ggtgcaaaca tttctgacca atggaccggt tcagaattgc
     7381 cacttgcctt tgcttcagat tcaaatccaa gcgacccagt ttcaaatgtt aatgacaagc
     7441 tcatttccta caataaccaa ccagccaatc gttggacaaa ctggaatcgt agtaatccag
     7501 aagcttcagt cggtgttctg tttggagatt caggtatctt gagcaaacgc tccgttgata
     7561 atctaagtgt cggattccac gaagaccatg gagttggtgc accgaagtct tatgtgattg
     7621 agtattatgt tggtaagact gtcccaacag ctcctaaaaa ccctagtttt gttggtaatg
     7681 aggaccatgt ctttaatgat tctgccaact ggaaaccagt tactaatcta aaagcccctg
     7741 ctcaactcaa ggctggagaa atgaaccact ttagctttga taaagttgaa acctatgcta
     7801 ttcgtattcg catggttaaa gcagataaca agcgtggaac gtctatcaca gaggtacaaa
     7861 tctttgcgaa acaagttgcg gcagccaaac aaggacaaac aagaatccaa gttgacggca
     7921 aagacttagc aaacttcaac cctgatttga cagactacta ccttgagtct gcagatggaa
     7981 aagttccggc agtcacagca agtgttagca acaatggtct cgctaccgtc gttccaagcg
     8041 ttcgtgaagg tgagccagtt cgtgtcatcg cgaaagctga aaatggcgac atcttaggag
     8101 aataccgtct gcacttcact aaggataaga acttactttc tcataaacca gttgctgcgg
     8161 ttaaacaagc tcgcttgcta caagtaggtc aagcacttga attgccgact aaggttccag
     8221 tttacttcac aggtaaagac ggctacgaaa caaaagattt gtcagttgaa tgggaagaag
     8281 ttccagcaga aaatctgaca aaagcaggtc aatttaccgt tcgaggccat gtccttggta
     8341 gtgatcttgt tgctgaggtc actgtacgag tgacagacaa actaggcgaa gctctttcag
     8401 ataaccctaa ctatgatgaa aacagtaacc aggcctttgc ttcagcaacc aatgatattg
     8461 acaaaaactc tcatgaccgc gttgactatc tcaatgacgg agatcattca gaaaatcgtc
     8521 gttggacaaa ctggtctcca acaccatctt ctaatccaga agtatcagcg ggtgtgatct
     8581 tccgtgaaaa tggtaagatt gtagaacgga ctgttgcgca agccaaactt cgtttctttg
     8641 cagatagtgg tacggatgca ccaactaaac tcgttttaga acgctatgtc ggtccagagt
     8701 ttgaagtgcc aacctactat tcaaactacc aagcctacga cgcagaccat ccattcaaca
     8761 atccagaaaa ttgggaagct gtgccttatc gtgcggataa agacatcgca gctggtgatg
     8821 aaatcaacgt aacatttaaa gctgtcaaag ccaaagctat gagatggcgt atggagcgta
     8881 aagctgacaa gagcggtgtt gcgatgattg agatgacctt ccttgcaccg agtgaattgc
     8941 ctcaagaaag tacgcaatcg aagattcttg tagatggaaa agaacttgct gatttcgctg
     9001 aaaatcgtca agactatcaa attacctata aaggtcaacg gccaaaagtc tcagttgaag
     9061 aaaacaatca agtagcttca actgtggtag atagtggaga agatagcctt ccagtacttg
     9121 ttcgcctcgt ttcagaaagt ggaaaacaag tcaaggaata ccgtatccac ttgactaagg
     9181 aaaaaccagt ttctgagaag acagttgctg ctgtacaaga agatcttcca aaactcgaat
     9241 ttgttgaaaa agatttggcc tacaagacag ttgagaaaaa agattcaaca ctgtatctag
     9301 gtgaaactcg tgtagaacaa gaaggaaaaa ctggtaaaga acgtatcttt acagcgatta
     9361 atcctgatgg aagtaaggaa gaaaaactcc gtgaagtggt agaagctccg acagaccgca
     9421 tcgtcttggt tggaaccaaa ccagtagctc aagaagctaa aaaaccacaa gtgtcagaaa
     9481 aagcagatac aaaaccaatt gattcaagtg aagctagtca aactaataaa gcccagttac
     9541 caaatacagg tagtgcggca agccaagcag cagtagcagc aggtttagct cttctaggtt
     9601 tgagtgcagg attagtagtt actaaaggta aaaaagaaga ctagaaattt tgataccttc
     9661 tttatcatta aagaccaaag aaaaactctt gtcctaaata gaagataaag agtctggaac
     9721 aaaatagttc tcaaccacaa aaaagctaga tatttccaat tgcggaactc tagcttttta
     9781 attttgagtc gttctcttat tgtatagtag attgaaacta gagtagtaca cttctacttc
     9841 taaaacattg ttagaaatcg atttgactgt ccttatcgat ttgtcctgtt cttatttcat
     9901 ttaactatat tttaggaggt tattggccat aagtaccaat cccatgtcaa ttctcacttg
     9961 acgcttgccc ctcagattac atctcttgta acccaaacaa gcctttaact gcccaaagac
    10021 aggttccaca tcaatcttgc gttgagcgaa aatctgtcta ccttggggag ataaaagcgc
    10081 ctgacattct ttagctttca agttttgata gcgttcgttc atatatagcc cccttttgag
    10141 gggctgattc aggttcatca gcgtagtaaa ccttgatttc ctgttgaaag tctgtctgtg
    10201 ttttctgatg tttggtatgg tgaaaacgat aataccagcc atcaggatgt gtgtagctat
    10261 cctccttgtc attatagtgc caattcgcta agtttttagc tgactgttta taccctctct
    10321 tttgttcctt atcaaacatg gcatatttaa tcagaagggg agtgatttct tcttgaaaat
    10381 agacttgtat ctgttcttga agtttggcgg agaatttctc tgtcgttttc ttccacacaa
    10441 aactatactt gttggcattg gcttcaatct tagttccgtc aataaacaaa caatctaagg
    10501 tcactaactc ttccattttt caatttttcg accagagaaa atcccttgtg aataggcaaa
    10561 tagaagagta gatacaagca ttttaaggtg ataagacggg cgatcaaagg catgatagaa
    10621 ggcgtggaaa tgacaatcct ccaaggtatt caccactttt tcaatagtaa aaacgagatg
    10681 gtcttgtggc aagaaggaac tgatttttag tggtaaagtt gtttgatttg tgttatagtg
    10741 aatatgcatg ggatagcctt tctaaatggt ttattgtgca attctatttt accaagacta
    10801 tcgcaaccat gcaaaaaagc aacggcaaat ccgttgcttt ttttggagat aagagactat
    10861 tgtcccagac tcttttcttt gtataaaatt gtatagtgtt attgtctata ctattttgta
    10921 gagaaagcaa aaatccctag aaaatgctta gggattcgac tatttcatta agaacaattc
    10981 aacaatcatt tctacataca tgataagggt taataagaat cctgcacgcc agaagaattt
    11041 gatgaattta ggatagtaaa agctgcgttt tttcaaaagg aagaaaaaga cgagaataat
    11101 ggctaggatc gagagggtta gccccagtct agggaggaaa ttatgggtaa aggttttagc
    11161 tgtaatcagg taatattcaa ataccaagac cggaaaagcc aaatccgcaa agtttcgtcc
    11221 tagttttttt aatctaaaaa gtttggttag gataatgcag acgactaagg tcagtatcaa
    11281 taataaaata gatgctaatt tcattaaaat catacccata ttgtatcata aaaaaaggct
    11341 aatggaaacg agaaacagag gaatttatag gaaagtcagg cttttgagat tgtgggtgat
    11401 ttttgttata atgaaagtta taaaatctta taataccttg aatgattatt atcgaaaact
    11461 ctttggagaa aagactttta aagtccctat tgatgcggga tttgactgtc ccaatcgtga
    11521 tggaactgtg gctcatggag gctgtacttt ttgtacggtt tcaggttctg gagatactat
    11581 tgtagcccca gatgcgccta tccgtgagca attttataag gaaattgact ttatgcaccg
    11641 taagtggccg gatgttcaga agtatctggt ttattttcaa aattttacca acacccatga
    11701 aaaggtggaa gttattcgag agcgttatga acaggctatc aatgagccag gtgtggtagg
    11761 aatcaatatt ggaatgcgcc cagactgttt accagacgaa accatcgaat atttggctga
    11821 gttatcggag tgcatgcatg tgacggttga attgggcttg tagactactt atgaagcaac
    11881 ttctgacctg attaaccgtg cgtattctta tgaattgtag gtggaaacgg tcaagcgttt
    11941 gagaaagtat cccaagattg agattgtttc ccatttgatt aatggtttgc ctggtgaaac
    12001 ccatgagatg atggttgaaa atgtccgccg ttgtgtcacg aataacgata ttcaagggat
    12061 taaactgcat ttgctccatc ttatgacaaa tactcgtatg caacgagatt accatgaggg
    12121 acgtttacaa ttgatgagtc aggacgaata tgtcagggtc atctgtgacc aactggaaat
    12181 tattcccaaa catatcgtca tccatcgaat cacaggagat gcacctaggg atatgctgat
    12241 tgggcttatg tggagcctca ataaatggga agctctcaac agcattgaga tggagatgcg
    12301 acgtcgtgga agtgttcaag gatgcaaggc tgtaaaacag gagtttgaaa atgaaaagac
    12361 cacttgagat ggcacatgat tttttggctg aggtcgtgac aaaagaggat gtcgtagtgg
    12421 atgcgactat gggaaatggt catgacacgc tttttttagc caagctagcc aagcaagtct
    12481 atgcctttga tattcagaag caagccttga aaaagaccca agagcgtttg catcaggctg
    12541 gcttgacaaa tgcccagtta atcttgcaag gccatgagac actggaccag tttgtgacaa
    12601 aaactaaggc agggattttt aatctgggct atttgccgtc agctgataag tctgtcatca
    12661 cccgaccgca gacaaccatt gaagcattag aaaagctatg tcatttgctt gtcaaaggtg
    12721 gacgaattgc tattatgatt tactatggtc atgaaggagg cgacctcgag agagatgctg
    12781 tcttggattt tgtgatccag ttgaaccaac aagagtacac agctgccatt taccgaactt
    12841 taaaccaagt caacaacccg ccgtttttag tgatgattga aaaattagag agatacagac
    12901 atggataaac aatacctaca cgaaaagctg gatgccatgc gccagaattt tgttgaatca
    12961 acccaccacg aacgagcggt gggcgtgcta gaccaagcgc atatgagcaa aaaaatgctt
    13021 aaaatcaaga aaaaattagt tgctcttgaa atggaacggt gccagagaaa aattgagcac
    13081 aaagattgtt ccaagattga ccaaaaaatc aaagagcaga aggagatatt tgaatcctgt
    13141 tgtaaaaaag attaaggagg acgtgcgtgg aattactgat ttacctcatc ctatttttac
    13201 tggttttgat tgtctcaagt acaaccaata agctcctgcc ctttttgcct ctccctttgg
    13261 tgcaaattct tttgggaatt gtgattggtc tctttttacc caataccgac tttcacctca
    13321 atacggagtt gtttttggcc ctggttatcg gacccttgct tttccgagag gctgaagaag
    13381 cagatgttac ggctatttta aaacactggc gaatcattgt ttatctcata tttccagtga
    13441 tttttatctc gaccctgagt ttgggtggct tggcccatct tctttggttc agccttccct
    13501 tggcagcttg cttggctgtt ggggcagccc ttggtcctac ggacttggtg gcctttgcct
    13561 ctctttcgga gcgttttagc tttcctaagc gcgtgtccaa tattcttaag ggcgaaggac
    13621 tcttgaatga tgcttctggt ttggtggctt ttcaggtagc tttgacagct tggacaactg
    13681 gagctttttc tctggggcaa gctagcagtt cgctcatctt ttcaatccta ggcggttttt
    13741 taattggatt tttaacagcc atgaccaacc gcttcctcca taccttcttg ctaagtgtgc
    13801 gcgcaacgga tattgccagt gaacttttat tagaattgag tttgcctcta gtgaccttct
    13861 ttctggcaga agaagtccat gtttcaggga ttattgccgt cgtagttgct ggaattttaa
    13921 aggcaagtcg cttcaagaaa atcacgctcc tcgaagccca agtggatacg gtgaccgaga
    13981 cggtctggca tacagtgacc tttatgctca acggttctgt ctttgtgatt ttagggatgg
    14041 agttggaaat gatagcagaa cctatcttga ccaatccaat ctataatcct ctacttttat
    14101 tgctatctct catcgtcctt acctttgtcc tctttgtcat tcgttttatt atgatctatg
    14161 gctattatgc ctatagaacc cgacgcctca agaaaaagct aaataagtat atgaaggaca
    14221 tgtttctctt gaccttttca ggtgttaagg gaacggtgtc gattgctacg attctcttga
    14281 taccaagtaa tctagaacag gagtatcctc tcttgctttt ccttgttgca ggtgtgacgc
    14341 ttgtcagctt tttaacaggt ctcttggtct tgcctcatct ttctgatgaa gaggaagaaa
    14401 gcaaggatta tctcatgcat atcgccattt tgaatgaagt aacgctagag ttggaaaaag
    14461 agttggaaga caccagaaat aaacttcccc tctatgcggc tattgacaat tatcatggac
    14521 gtattgaaaa tctcatttta agccaagaaa accaggatga tcaagaagat tgggctgctt
    14581 tgaaactctt gattcttagt attgaaagtg atggtttgga acaggcctat gaagagggga
    14641 acattagcaa tcgtgcttac cgagtttacc aacgttatct gaaaaatata gaacaaggaa
    14701 tcaatcgtaa acttgcctca agactgacct attatttcct tgtttctttg cggattttac
    14761 gttttctcct tcatgaagtt tttactctcg gaaagacctt ccgtagctgg aagaacaagg
    14821 agcaaagccg tctccgtgct cttgattatg accaaattgc agagctctat cttgccaata
    14881 cggagatgat tattgaaagt ttggaaaacc tgaagggagt ctacagacgc tctttgatta
    14941 gttttatgca ggagtctcgt cttcgagaaa caactattat cagcagtggt gcctttgtcg
    15001 aacgggttat caatcgtgtc aaacccaaca atatcaatga aatgctgaga ggctattatc
    15061 tggagcgcaa gttgattttc gaatacgaag aaaaacgatt aattacaact aagtatgcca
    15121 agaaattacg acaaaatgta aataacttag agaactattc cttgaaggaa gctgccaata
    15181 ccctgccgta tgatatggtg gaattggtaa gaagaaatta gttaatactc ttcgaaaatc
    15241 tcttcaaacc acgtcagcgt cgccttaccg tatgtatgtg actgacttcg tcagtcttat
    15301 ctacaacctc aaaacagtgt tttgagcagc ctgcggctag cttcctagtt tgctctttga
    15361 ttttcattga gtataagatt ataagtgaag gagtgtgaca tgaaaaagtg gtggaaagag
    15421 ctgatagaca agcctttatt aaaagctttt ttgcattatt atcaagcatc agatagtgag
    15481 ttgaccagtg tcgcagtagc ctactattgg ttgatttcga ttttccccct gcttttggtg
    15541 gtggtcaata tcctccccta ttttcagatt cctgtgggag aatttctggg ctttatgaaa
    15601 gacgtcctgc ccccaagcct ctatgaaggt gtggaaaaaa tagccagaga agtcttgacg
    15661 caaccttcaa caggtttatt gagtttttct gttttatcgg cgttatggag tttttcaaaa
    15721 tctatgaatt tcttgcaaaa agcttttaac aaggcttatg gcgtcgaaaa gagtcgtgga
    15781 cttatttccc atcagatgct aagtctccta gtcagttttg gcttgcagct cctctttgcg
    15841 tttgccttgt ttttgatctt atttggtcag atgattttgg ctttacttgc tcattattgg
    15901 acaaaagatg gcattatcta tcaggcttta caagggttgg caggtcctct gatttacgcc
    15961 ctcctctttg ctatcttggt catgctttat tattttcttc ccaatatatc taacaggaaa
    16021 attagctata ccctaccagg cagtgccttt gttctcttag tgattttagg tttactaact
    16081 ctgttctcta gttatctcaa ttactatgtc catcatttgg tggatgtccg aattttaggt
    16141 tccgttcttc ttgttgttat gatgttttgg tttatcttga ttgctaaaat tgttatccta
    16201 ggcgcggtta tcaatgccag tatgcagagt ttgaaagatc cggtctttaa aaaagactaa
    16261 ctatttatcc attacaaaag cgcatagtat caaaacttta tagaaccttg atactatgcg
    16321 cttttgtgct ttgacagttt tttgtatagt ttttgtccaa gatttctaaa tcatctgatt
    16381 aaattcctat tttcccctat cattgtccct gttttttcga aaatggaagg agtataataa
    16441 atctatcaat aaaatgatag gaggaacttt atgggtcata ttttcttttt tctaagtgtc
    16501 tttttggcag ggattctatc cttcttttct ccttgtatct tacctttgtt accggtctat
    16561 acaggagtgt tactagatga taaggatggt gctcaggctt ctagcggcaa attttcaatc
    16621 tcagttacta gtttattacg aactctggcc tttatagcag gaatttcctt tatatttatt
    16681 ttgttgggct atggagctgg ttttttaggc gatttgcttt atgcttcttg gttccaatat
    16741 cttactgggg caattattat ccttcttggt ttgcaccaaa tggagattct acactttaag
    16801 gggctttata aggaaaagag gctacaactg caaggacagg ggcaaaatgg taagggctat
    16861 agtcaggcat ttttattggg cttgaccttt agttttgctt ggacgccttg cgtggggccg
    16921 gttctggggt ctgttttggc cttggcggct tcaggtggtt caggagcttg gcagggagct
    16981 ggtctcatgt tggtgtatac gctgggcttg gcgctaccat tcttgcttct agctctgacc
    17041 tctagttatg ttttgaaaca tttccgaaaa cttcatccct atctcggaat cctcaaaaaa
    17101 gtgggtggtt ttctcattat tgtgatggga ctcttggttc tgtttggaaa tgcttcaatt
    17161 ttaagtcaat tatttgaata aaatggaaag gaatatcaat atgaaaaaat ggcaaacatg
    17221 tgttcttgga gcaggttcgc tcctttgttt gacggcttgt tcaggcaagt ccgtgactag
    17281 tgaacaccaa acgaaagatg aaatgaagac ggagcagaca gctagtaaaa caagcgcagc
    17341 taaagggaaa gaggtggctg attttgaatt gatgggagta gatggcaaga cctaccgttt
    17401 atctgattac aagggcaaga aagtctatct caaattctgg gcttcttggt gttccatctg
    17461 tctggctagt cttccagata cggatgagat tgctaaagaa gctggtgatg actatgtggt
    17521 cttgacagta gtgtcaccag gacataaggg agagcaatct gaagcggact ttaagaattg
    17581 gtataaggga ttggattata aaaatctccc agtcctagtt gacccatcag gcaaactttt
    17641 ggaaacttat ggtgtccgtt cttacccaac ccaagccttt atagacaaag aaggcaagct
    17701 ggtcaaaaca catccaggat tcatggaaaa agatgcaatt ttgcaaactt tgaaggaatt
    17761 agcctaggag gtgtcttatg aatgataagt taaaaatctt cttgttgcta ggagtatttt
    17821 ttctagccat aaccggtttc tatgttctat tgatacgaaa tgcagggcag acagatgcct
    17881 cgcaaattga aaaggcggca gttagccaag gaggaaaagc agtgaaaaaa acagaaatta
    17941 gtaaagacgc agacttgcac gaaatttatc tagctggagg ttgtttctgg ggagtggagg
    18001 aatatttctc acgcgttccc ggggtgacgg atgccgtttc aggctatgca aatggtagag
    18061 gagaaacaac caagtacgaa ttgattaacc aaacaggtca tgcagaaacc gtccatgtca
    18121 cctatgatgc caagcaaatt tctctcaagg aaatcctgct tcactatttc cgcattatca
    18181 atccaaccag caaaaataaa caaggaaatg atgtggggac ccagtaccgt actggtgttt
    18241 attacacaga tgacaaggat ttggaagtga ttaaccaagt ctttgatgag gtggctaaga
    18301 aatacgatca acctctagca gttgaaaagg aaaacttgaa gaattttgtg gtggctgagg
    18361 attaccatca agactatctc aagaaaaatc caaatggcta ctgccatatc aatgttaatc
    18421 aggcggccta tcctgtcatt gatgccagca aatatccaaa accaagtgat gaggaattga
    18481 aaaagaccct gtcacctgag gagtatgcag ttacccagga aaatcaaaca gaacgagctt
    18541 tctcaaaccg ttactgggat aaatttgaat ccggtatcta tgtggatata gcaactgggg
    18601 aacctctctt ttcatcaaaa gacaaatttg agtctggttg tggctggcct agttttaccc
    18661 aacccatcag tccagatgtt gtcacctaca aggaagataa gtcctacaat atgacgcgta
    18721 tggaagtgcg gagccgagta ggagattctc accttgggca tgtctttacg gatggtccac
    18781 aggacaaggg cggcttacgt tactgtatca atagcctctc tatccgcttt attcccaaag
    18841 accaaatgga agaaaaaggc tacgcttatt tactagatta tgttgattaa tactcttcga
    18901 aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt agggttactg acttcgtcag
    18961 ttttatctac aacctcaaag ctatactttg agctgacttc gtcagtttta tttacaacct
    19021 caaagcggta ctttgagaaa cctgtggcta tcttcctagt ttactttttg atttttattg
    19081 agtataagag gtctttccta agcagttaga ggagaatttt gctatactga tactagtaag
    19141 tggtaaagga gcagatcatg acctacacaa tcttaatcgt agaagatgaa tatctggtaa
    19201 gacaaggttt gactaaactg gtcaatgtag cagcctacga tatggaaatc atcggtcagg
    19261 ctgaaaatgg aaggcaggct tgggaattga tccaaaagca ggtgccagat atcattttaa
    19321 ccgatatcaa catgcctcat ctaaatggca tccagttggc cagtctggta cgagaaacct
    19381 atcctcaggt tcatttggtc tttttaacag gttacgatga ttttgattat gccttgtctg
    19441 ctgtcaaact aggtgtggac gactacctgc tcaaaccctt ttctcgtcag gatattgagg
    19501 aaatgttggg gaaaatcaaa caaaaactag acaaggaaga gaaagaagag cagttacaag
    19561 atttattgac taataggttt gaaggaaaca tggcccagaa aatccagtct catctggctg
    19621 atagccaatt tagtttaaag tctttagcca gtgacttagg ttttagtccg acctatctga
    19681 gttccttgat taagaaagag ttgggcttgc cttttcagga ttatctggtg agagaacgtg
    19741 ttaaacaagc caagctcttg cttttaacta cagatctgaa gatttatgag atcgcagaga
    19801 aggttggttt tgaagatatg aactatttta cccaacgttt taagcagatt gcaggtgtga
    19861 cacctcgtca gtttaagaag ggagaagacc gatgaagcgt tcttctcttt tagttagaat
    19921 ggttatttcc atctttctgg tctttctcat tctcctagct ctggttggaa ctttctacta
    19981 tcaatcaagt tcttcagcca ttgaggccac cattgagggc aacagccaaa cgaccatcag
    20041 ccagactagc cactttattc agtcttatat caaaaaacta gaaaccacct cgactggttt
    20101 gacccagcag acggatgttc tggcctatgc tgagaatccc agtcaagaca aggtcgaggg
    20161 aatccgagat ttgtttttga ccatcttgaa gtcagataag gacttgaaaa ctgttgtgct
    20221 ggtgaccaaa tctggtcagg tcatttctac agatgacagt gtgcagatga aaacttcctc
    20281 tgatatgatg gctgaggatt ggtaccaaaa ggccattcat cagggagcta tgcctgtttt
    20341 gactccagct cgtaaatcag atagtcagtg ggtcatttct gtcactcaag aacttgttga
    20401 tgcaaaggga gccaatcttg gtgtgcttcg tttggatatt tcttatgaaa ctctggaagc
    20461 ctatctcaat caactccagt tggggcagca gggctttgcc ttcattatca atgaaaacca
    20521 tgaatttgtc taccatcctc aacacacagt ttatagttcg tctagcaaaa tggaggctat
    20581 gaaaccctac atcgagacag gtcagggtta tactcctggt cacaaatcct acgtcagtca
    20641 agagaagatt gcaggaactg attggacggt gcttggcgtg tcatcattgg aaaagttaga
    20701 ccaggttcgg agtcagctct tgtggacctt gcttggggcc agtgtcacat ctcttcttgt
    20761 ctgtctctgc ttagtgtggt tcagtcttaa acgctggatt gctcctttga aggatttgag
    20821 agaaaccatg ttggaaattg cttctggtgc tcaaaatctt cgtgccaagg aagttggtgc
    20881 ctatgaactg agagaagtaa ctcgccaatt taatgctatg ttggatcaga ttgatcagtt
    20941 gatggtagct attcgtagcc aggaagaaac gacccgtcag taccaacttc aagccctttc
    21001 gagccagatt aatccacatt tcctctataa cactttggac accatcatct ggatggctga
    21061 atttcatgat agtcagcgag tggtgcaggt gaccaagtcc ttggcaacct atttccgctt
    21121 ggcgctcaat caaggcaagg acttgatttg tctctctgac gaaatcaatc atgtccgcca
    21181 gtatctcttt atccagaaac aacgctatgg agataagctg gaatatgaaa ttaatgaaaa
    21241 tgttgccttt gataatttag tcttacccaa gctggtccta caaccccttg tagaaaatgc
    21301 tctttaccat ggcattaagg aaaaggaagg tcagggccat attaaacttt ctgtccagaa
    21361 acaggattcg ggattggtca tccgtattga ggatgatggc gttggcttcc aagatgctgg
    21421 tgatagtagt caaagtcaac tcaaacgtgg gggagttggt cttcaaaatg tcgatcaacg
    21481 gctcaaactt cattttggag ccaattacca gatgaagatt gattctagac cccaaaaagg
    21541 gacgaaagtt gaaatatata taaatagaat agaaactagc taactcccag tcaattctgg
    21601 gagttttatg cgtaattggg caaattttct aggttgtcta tcttgctaaa aacaagaaaa
    21661 aacggtatga tagaagagtg acaacagagg taacagagat gaacgagaca cagattcaaa
    21721 gagaaacacg tcaggtagtg gaagatgttt tagaaaagac caatttgaag cagggggccc
    21781 tttttgtttt aggtctatct tctagtgagg tgctaggtgg tcagattggg aaagaatcca
    21841 gtcaagagat tggtgagctg atagtggaga ctatcttggg tattctaggt agtagaggta
    21901 tccatttagc agttcaaggt tgtgagcatg tcaatcgggc tctcgttgtt gaacgtcagg
    21961 tggcagagca gtttgatctg gaaattgtca gtgtccatcc tactcttcat gcaggaggtt
    22021 cggggcagtt ggcagccttt aagtttatgc aggatccagt tgaggttgaa tttatcaagg
    22081 ctcatgctgg attggatatc ggagacactg caattggcat gcatgtcaag catgttcagg
    22141 ttccgattcg ccctattttg agagagattg gtcatgccca tgtaacggca ctggctagtc
    22201 gtccaaaatt aatcggaggt gcgcgtgcgc actatccgca agatgctatt aggaagtctt
    22261 gagaatgaat aaaggagata aaagtgttta aaaaagaccg tttttcaatt cgtaagatta
    22321 agggagttgt aggctctgta tttcttggaa gccttttgat ggctccttct gtagtggacg
    22381 cagccaccta tcactatgta aataaagaga ttatttcaca agaagctaaa gatttaattc
    22441 agacaggaaa gcctgacagg aatgaagttg tatatggttt ggtgtatcaa aaagatcagt
    22501 tgcctcaaac agggacagaa gcatctgttt tgacagcttt tggtttgctg actgttggga
    22561 gcttgctttt aatctacaag agaaagaaaa ttgctagcgt ctttctagtt ggagctatgg
    22621 gattggtagt tcttcctagt gcaggggctg tagacccagt tgcgacccta gcgctggcta
    22681 gtcgagaggg tgttgttgaa atggatggct atcgctatgt tggttatcta tcaggtgaca
    22741 tcctcaaaac gcttggcttg gacactgttt tagaagaaac ctcagcaaaa cctggagagg
    22801 tgactgtagt cgaagttgag actcctcaat caataacaaa tcaggagcaa gctaggacag
    22861 aaaaccaagt agtagagaca gaggaagctc caaaagaaga agcacctaaa acagaagaaa
    22921 gttcaaagga agaaccaaaa tcggaggtaa aacctactga cgacaccctt cctaaagtag
    22981 aagaggggaa agaagattca gcagaaccag ctccagttga agaagtaggt ggagaagttg
    23041 agtcaaaacc agaggaaaaa gtagcagtta agccagaaag tcaaccatca gacaaaccag
    23101 ctgaggaatc aaaagttgaa caagcaggtg aaccagtcgc gccaagagaa gacgaaaagg
    23161 caccagtcga gccagaaaag caaccagaag ctcctgaaga agagaaggct gtagaggaaa
    23221 caccgaaaca agaagagtca actccagata ccaaggctga agaaactgta gaaccaaaag
    23281 aggagactaa aacagctaag gggacgcaag aagaaggcaa agaaggtcaa gcaccagtac
    23341 aagaagtaaa cccagaatat aaagtaacaa caggtacagt tgagaagtct accgaaagtg
    23401 aattagattt cacaacagaa gtagttccgg atgacacaaa atatgtagat gaagaagttg
    23461 ttgaacgtca aggatctaaa ggagttcaag ttacgaaaac aacttacgaa acagtggaag
    23521 ttgtagagac agacaaagtc ctttctacaa ctacagaagt gaaaactcct gttgttccta
    23581 aagtcgttaa aaaaggaaca aaaccagttg aaggaacagc agttgaaaca agagaagaag
    23641 tcattccttt tgctacaaaa gaacaagaag atgacacttt aaaacgcgga acaagacaag
    23701 tagctcaaga aggtgtaaac ggtaagaaac aaattactga aacctataaa acaattcgcg
    23761 gagaaaaaac aaacgaagct ccaacagtag aagaaacagt tctccaagca cctcaagatg
    23821 agattatcaa aaaaggcaca aaaggtttag aaaaaccaac cttagaatgg gttaaaacag
    23881 ataaagatgt cttgaagaag agtgcgacag ccagttatac attgaataaa ccagatgggg
    23941 tagaaatcaa atccatcaaa gtagctctaa aagataatac tggaacagtt attaaagaag
    24001 taacggtaga agaaaataac ttaaacgcta ctttagacaa cttgaaatat tatcaaggtt
    24061 atacactatc cacaaccatg gtctataatc gaggcgaagg cgaagaaact gaaatgttag
    24121 aagataaaga agttcagtta gaccttaaaa aagttgaaat caaaaacatc aaagaaacta
    24181 gcttgatgag tgtggatgat gctggtgttg aaacagataa gagcttactt actgaaaaac
    24241 cgacagacgt tgctccactt tacctacgag tgacaactca tgataacaaa acaacaagac
    24301 tggcagtaag ttcagttgaa gaagttgttg ttgatggaaa aacattgtac aaagtggtag
    24361 ctaaagctcc tgacttagtt caacgtagag aagatgatac actaagcgaa gagtatgtac
    24421 attactttga aaaacaatta ccaaaagtag ataatgtgta ctatagcttt aacgagttaa
    24481 ttacagatat gcaaaaaaat cctactggta cattcaaact aggtgcagat cttaatgcag
    24541 cgaatactcc aactccaagt aaatcatatg taacaggtga atttaaaggt aaattatcaa
    24601 gtgttgatgg tcaacattat acgattcaca atactgcgcg cccattattt aacaatattg
    24661 ttggtggtac cgttaaaaat attaatctta acaatgtaaa tatcgatatg ccttgggctg
    24721 atcaaattgc atctgtagca aatgtgatca aaggtggtag ccttattgag aatgttaaag
    24781 tcaaaggtaa tgtgctcggc agaaactggg tatctggttt cattgataaa attgacagtg
    24841 gtggtagatt agttaatgtt gcatttattg gtaatgtaac ttctgttgga gatggggata
    24901 agttcttaac aggtattgtt ggagaaaact ggaaaggata tgtcgaaaaa gcatacgttg
    24961 aagctaatat taaaggtaag cgagctaaag ctgctggtat atcttattgg tcgcaaaata
    25021 gcggagataa taatgctgtc ggtagagatg gagcaattaa gaaatctgtc gttaaaggtt
    25081 caatagatgt agaaaaacca attgaagttg gtggcgctgt tggaagttta aattatcttg
    25141 gttatataga agacactgtt gctatgatga aagttaagaa cggtgaaatt ttctacggtt
    25201 cgcatgatat cgataccgat ccatattaca caggagaacg agtaaataga aatttcattg
    25261 ttgacggtgt aagtgaaggt aaatcttcgt atacatactc taaacaacaa aagcgtatta
    25321 aatcaatatc tcaagaggaa gcagataaga aaattaaaga attgggtatc acagcagata
    25381 aatttacaat tatcgatcca attgtaaata aacttaacaa catcaaacaa aaagctgata
    25441 cttataaaga tactcaagat tacaaagtag accgtgaact tgcttatcgt aatatcgaaa
    25501 aacttcaacc attctacaat aaagagtgga ttgtagacca aggtaataaa gttccatcaa
    25561 attctaaatt attaactaca gaagtattat ctgttacagg tatgaaagat ggtcaatttg
    25621 tgactgactt atcagaaatt gataaaatta tgattcacta tgcggatggt acaaaagaag
    25681 aaaaatctgt atcacctaag cctacatcaa acgtagaaca agtaaaagaa tatggtatta
    25741 cagatttagg agatgtcgtt tacacaccaa atatggtggt taaagaccgt gctcaattac
    25801 taagtgatgt taaagcgaaa ttagatacga ttactcttga atctcctgaa gttcgtgcga
    25861 taacaggtaa tgttggagca ttatacttag aagaaagttt tgcagaagta aaaggaaatc
    25921 ttgataaatt agtaaaagct cttgttgaaa atgaagatca tcagttaaat agtgatgagg
    25981 cagccatcaa agcatttctt aagaaagtag aagataataa agctaaaatc atgatggcac
    26041 ttacttacct caatcgttat tatggtattg aatatggtga cttaaacatt aagaatataa
    26101 tgatgtttaa accagatttc tatggcaaga caccaagtgt tattgataga ttaattcgaa
    26161 ttggttcgca agaaaagaac ttgaagggtg atagaaccca agatgcatat cgtgaaatta
    26221 ttgcaggaga tactggtaaa ggtgatttac gtagtttctt agattataat atgcgtctct
    26281 tcacaaatga tacagatctt aatgactggt ttatccattc agcgaaaaat gtttatgttg
    26341 tagaaccaga aacaacaaat ccagatttca aaaataaacg tcatcgtgtt tttgatggtc
    26401 tgaataataa tatgcatgca cgtatgattt taccattatt gaacttgaaa aaagcacata
    26461 tctttatgat ttcaacctat aatactatgg cttatagttc atttgaaaaa tatggtaaaa
    26521 atacggaagc tgaacgtgaa gcgttcaagg aacgtatcaa ttatgtagct aaagctcaac
    26581 aaacatactt agacttctgg tcacgtcttg cacttacaaa tgttcgtgat agacttctta
    26641 agagtcaaaa tatggttcct acacctgtat gggataatca agcttatgcg ggtattaagg
    26701 atgctaatcg tcgtggatat ggtacagatg gtaaggtagc gacaccaatt cgtgagttat
    26761 ttggtccaac agacagatgg catcaaatta attggaatat gggagctatg gctaaagttt
    26821 atggaaaacc atatgaagat gaacaagttt tcttcatggt aacaaatatg ttagaggact
    26881 ttggtatttc agcctttaca catgaaacaa ctcacataaa tgaccgtatg gcatatcttg
    26941 gtggtcatgg acatcgtcca ggtacatacc ttgaagcata tgctcaaggt atgttacaaa
    27001 cacctgataa atcaacatca aatggtgagt atggagcatt aggtattaat atggcttatc
    27061 atcgtcaaaa tgacggaaat cagtggtata acccagatcc tgataaatta caaagtcgtg
    27121 aacaaattga tcactatatg aagaactaca atgatgctct tatgatgtta gatcatcttg
    27181 aggctgatgc tgtattaccg cagttaaatg gaaatacgag tcgctggttc aagaaaatgg
    27241 atagacaata ccgtagtgga aattcaggtc atcagttcga taaaattcgt gagttgacag
    27301 aggatgagaa aaaagtagca atcaatacaa ttgatgattt aattactaat aacctaataa
    27361 cgaaacatgg tgctcctggt gatggtactt ataatccaac ggactttagg tctgcttatg
    27421 ttaatatgaa catgatgact ggtatttatg gtggaaatac aagtacaggt gcaccgggtg
    27481 cagcatcatt taaacataat acattccgta tgtggggata ctttggatat gagaatggat
    27541 ttgttggata tgcttctagc aaatatcaaa atgcagccaa taaagaaaat aataggatgt
    27601 taggtgatga cttcattatt aagaaagttt caaatggaag attcactaac cttgaagatt
    27661 ggaagaaaga gtactataaa gaagtgaagg caaaaggtga aaaaggattt actgcaattg
    27721 agattgatgg taaacaaatt accaattatg ctgaactaaa agtcttattt gataaggcgg
    27781 ttgaggctga tctagcaggt ggaggaacag ctaaaactgt agaacttaaa tcgaaagtct
    27841 ttaaagcact tcttaagaat tcagacggat tcacaggaaa tctttttaaa gcatagattg
    27901 tattaaatag atgagtaaaa aggtagatta agtttttctt gatctgcctt tttatgctat
    27961 acttaaggta tgcatagaaa aacagtgatt gattttaggg ctttagggga gagacacatc
    28021 tttactcagc ctatcaaaga gttaaaaacc agagatttaa cagaagtaac agccttattg
    28081 gcacaagtgg aaagctacca agagcaaggt tattatgtgg tggggtatgt cagctacgag
    28141 gctgcacctg cttttgagga aaaattagca gttcacaagg atcccctact gggagagtac
    28201 ctgctttatt ttactgttca tgatagcgta gaaacttccc ctattcctct gacttatgag
    28261 gatattgatt tgccctcaaa ttggcaggaa gtaacgtctg cagcagacta tgaaaaggcc
    28321 attgcccaaa ttcaccatca tttacggcag ggagatacct atcaggtcaa ctacaccgtc
    28381 caacttaagc aaaagttaaa tgccaatcct tttgccatct acaatcgtat ggtggtagag
    28441 caggaggcgg gctacaatgc ctatgtggaa catgacgaga tggcagtgat ttccatgagc
    28501 ccagagctct tttttgagca aaatgatcgc gagttgacaa cacgaccaat gaaggggacg
    28561 actcagcgtg gggtaactga ccaagaagat cttgaacagg ccagttggtt ggaacaggat
    28621 cccaaaaatc gctctgaaaa tatgatgatt gtggacctct tgcgcaatga tatgaaccgt
    28681 atttctgaag ttgggagcga gcacgtggag cgtctgtgtc aggtagagca gtattcaact
    28741 gtttggcaga tgacttcgac catcaagagt cagttgcgag aggatgtgga ccttgttgaa
    28801 atcttccgct cactctttcc ttgtggttcc ataacgggtg caccgaaaat tgcgacaatg
    28861 gagattatca aggacttgga gcctcaaccg cgtggagtct actgtggaac gattggtctc
    28921 ttgcttccaa atggacgacg gatttttaat gtggccattc gtaccattca acttcacaaa
    28981 ggtcaagcca tttatggagt tggcggaggg attacttggg atagcacatg ggaatctgaa
    29041 taccgagagg ttcatcaaaa ggcagcagtt ctttatcgta aacaagctcg cttccaactg
    29101 attacgacag gggaaatcag ccagaagaac ctgctgtttg aagatcaaca tctggaaaga
    29161 ctgagaaaag ctagtcgtta ttttgccttt ccttttgatg cagaagactt gggacacaag
    29221 attgaggaag agtgtcagga ttgtgaagct aatcaagatt accgcttgcg aatcagcctt
    29281 agcaaatctg gagagataga agtcaatcgt caagtattaa cccctctcag tacaagcttt
    29341 tgtcaggccc aagtctgcct tcaggaagct gctttgaatc aatcctttac ctactttaaa
    29401 accactcacc gaccgcattt gagcctagga gaacaagaga agatttacca caataagtca
    29461 ggagaactgc ttgaaacctc tataggaaat ttggttctga aaatcgctgg aaaactctac
    29521 acaccgccta tccgacttgg aatcttgcca ggaatttacc gtcagcattt gctagaaaca
    29581 ggacaggtag aagagaaagt cttgaccttg gcagatttaa cccaagcaga agctatttac
    29641 ggctgtaatg cagtgagagg cttgtatgaa ctaagccttg aggagaacta gatgaaattg
    29701 atatttttgc atgggttagg gcagtcagca gagtcttgga aagaagttcg gaatctactg
    29761 acagattatc cttctgaggc tatcgagtta tttccttctg gagttagtaa ctatcaacaa
    29821 gctaaagagc gagtttatca gcacctagct caagagacag aaccttttgt tttgattgga
    29881 ttgtccttag gtgctgccct gacactagaa ctttccagtt acgatttacc aaatcttcga
    29941 gctttgattc tgtcaggatg cccgcttaaa ttagcaggga atatcctatt ttatcttcag
    30001 ttgctgattt ttaaactact tcccaaaaga gtatttgaaa aacagggagc agacaagact
    30061 cttatggtcg gagtttctga ggaattgaag acacttgatt taacggatat agcagggact
    30121 tgctcctatc caaccttact aatttgtggc agcaaagata aaccgaatct tagttctatg
    30181 aaagctctcc atagactgtt aacagattcg cagtttcaga tcattcctga tggctctcat
    30241 gtcttgaata aggcaaaacc aaaggagttt gtagaaaaga ccagaagttt ccttgaattg
    30301 ctgaaataag tttgataaaa taatattgaa atcgatatca taattatggg agaaagaaat
    30361 gaataaacgt ctatttttaa aaatgagtct ggtgacgttg ccaattttag ccttgttttc
    30421 acaaccagtt ttggcggaag aaaacatcca tttttcgagc tgtaaggaag cttgggcgaa
    30481 tggctattcg gatattcacg agggggaacc tggttattct gccaagttag accgtgatca
    30541 tgatggtgtg gcttgcgaat tgaaaaatgc tcctaagggt gcttttaaag caaaacagtc
    30601 aacggctatt caaatcaaca caagttcagc aacaacaagt ggttgggtta agcaggacgg
    30661 ttcttggtac tactttgatg gaaatggaaa tctagtgaaa aatgcatggc agggaagcta
    30721 ttacctgaaa gctgatggta aaatggcaca gagtgaatgg atttatgact cttcttatca
    30781 agcttggtat tatttgaaat cagatggttc ttatgcaaaa aatgcatggc aaggagctta
    30841 ttaccttaaa tcaaacggta aaatggcaca aggtgagtgg gtttatgatt cttcttacca
    30901 agcatggtat tacttgaaat cagatggttc atatgctcgc aatgcatggc aaggaaacta
    30961 ctatttgaaa tcagatggta aaatggctaa aggtgaatgg gtttatgttg ccacctatca
    31021 agcttggtat tatttgacat cagatggttc ttatgcttac agtacatggc aaggaaatta
    31081 ctatctaaaa tcggatggta aaatggctgt caatgaatgg gttgatggtg gacgttatta
    31141 tgttggcgct gacggagttt ggaaggaagg tcaagcaagt acagcttctt ctagtaatga
    31201 tagcaatagt gaatattctg ctgctttagg aaaggcaaaa agttataatt cgttattcca
    31261 catgtcaaaa aaaacgtatg tatagacaat taacttctga ttttgataaa ttttcaaatg
    31321 atgcagctca atatgccatt gatcattaga tgattaacag atactggtag gcgaaaaaat
    31381 tccttataat tcatttacgc aaacctttgc ataagtgaat ggattttgat atactagtac
    31441 tgtaagcatt ttcaattact acacaatgaa aaaggagaat atgatgagtc aaaagattat
    31501 tgggattgac cttggtggaa cttctatcaa atttgcaatc ttaacaacag caggagaaat
    31561 ccaaggaaaa tggtcaatca agaccaacat tttggatgag ggaagtcata tcgttgatga
    31621 tatgattgag tctattcaac atcgtttgga cttgcttgga ttggcagcag cggacttcca
    31681 aggcattgga atgggatcac caggtgtggt tgaccgtgac aaagggactg ttatcggtgc
    31741 ctacaacttg aactggaaaa cccttcaacc aatcaaacaa aagattgaaa aagctttggg
    31801 cattccattt ttcatcgata atgatgccaa cgtagcagct cttggtgagc gctggatggg
    31861 tgctggagat aaccaaccag acgttgtctt tatgacactc ggtactggtg ttggtggtgg
    31921 tattgtcgca gaaggcaaat tgcttcatgg tgttgctggt gcagcaggtg aacttggtca
    31981 tatcactgtt gactttgacc aaccaatctc atgtacttgt ggtaaaaaag gctgccttga
    32041 gacagttgct tcagcaacag ggattgtcaa cttgactcgt cgctatgccg atgaatacga
    32101 aggcgatgca gccttgaaac gcctgattga taacggagaa gaagtaactg ctaagactgt
    32161 ctttgatctc gcaaaagaag gagacgacct tgctttgatt gtttaccgta acttctcacg
    32221 ttacttggga atcgcttgtg ctaacattgg ttcaatccta aacccatcaa caatcgtcat
    32281 cggtggtggt gtgtcagctg cgggagaatt ccttctacaa ggtgttcaaa aagtttacga
    32341 tgaaaatagt ttcccacaag tacgcacatc tactaaatta gctcttgcaa ctctaggaaa
    32401 tgacgctgga gttatcggag cagcatcact tgtattgcaa taagataatg agagaggaaa
    32461 atgctaacct agagttagta atgttcctct tttatttttt atgctatact agttaggaca
    32521 atgaatgagg tgaaacgaaa tgacaaaagc agatacgatt tttaaagaga atattgaacg
    32581 cattctaaag gaaggtgttt tctcagagca ggctcgtcct aagtacaagg atgggactgt
    32641 tgctaattcc aagtatgtaa ctggtgcctt ttccgagtac gacttatcta aaggagaatt
    32701 tcctatcaca accttgcgtc ccattgcaat caaatccgcc atcaaagaag ttctctggat
    32761 ttaccaagac cagtcaaata gcttagaggt acttaatgat aagtacaatg ttcactactg
    32821 gaatgactgg gaagtggggg atacaggaac tattggtgaa cgctacggtg ctgttgttaa
    32881 gaaacacgac atcatcaaca agcttttcaa acagttggaa gccaaccctt ggaaccgccg
    32941 caatatcatt tcgctctggg attaccaagc tttcgaagaa acagatgggc tactcccatg
    33001 tgcctttcag accatgtttg atgtccgccg tatagatgga gaaatctatc tggatgcgac
    33061 cttgacccag cgctcgaatg acatgctagt agcccaccac atcaacgcta tgcagtatgt
    33121 ggctttgcag atgatgattg ccaagcattt tggctggaag gttggaaagt tcttctactt
    33181 catcaacaac ctccatatct atgacaatca atttgaacaa gctcaggaat tactccgtcg
    33241 tgaaccgtca aactgccaac cacgtttggt tttgaatgtt cctgatggaa ctaatttctt
    33301 tgatatcaaa gcagaagatt ttgaattggt ggattatgac cctgttaagc cgcagttgaa
    33361 gtttgaccta gctatttaaa agaatagaaa aaagaagttg agaataatcc caacttcttt
    33421 tgtttcttaa cgtgatacgc ggcgacgagc tgctttttta cggttttctt cgatgaaagc
    33481 tgctttttgc tcttctggtt cgattacttt ctttttaaat gcgtatactg cacctgcaac
    33541 ggcagcgaca gttcctgcga cacctgttac aagaccttta gcgaatcctt tagccatgag
    33601 tcttcctcct ttatattctc aatcagccag cctcctcaag aggtcacatt tttctgactg
    33661 acctttttgt gttataataa tagtaacgaa aaaatgggaa tttttcaagg aaaaaagatg
    33721 aaaacaaaaa taattgtgat tgttggaccg actgctgttg gaaagacggc tctagctatt
    33781 gaagttgcaa agcgttttaa tggcgaagtg gttagtggag atagccaaca agtctatcga
    33841 ggacttgata ttgggacggc caaggctagt ccagaagagc aggcagctgt tcctcatcat
    33901 ttaatcgatg ttagagagat aaccgagtct tactcggctt ttgattttgt ttcagaagct
    33961 aagatgacta ttgaggatat tcacagccgt ggcaagctag ccattatcgc cggtgggact
    34021 ggactttata tccagagctt gctagaaggt taccacctag gtggggagac tcctcatgag
    34081 gagattttag cttatcgagc tagtttggag ccatattcag atgaggaatt agcccatttg
    34141 gtggagcaag caggccttga gattccccag tttaatcgtc gtcgtgctat gcgtgcctta
    34201 gaaattgccc attttggtca ggatttggaa aatcaagaga ttttgtatga accgctgatt
    34261 atctgcttgg atgatgaacg tagtcaactt tatgagcgta tcaaccaccg agtggatttg
    34321 atgtttgagg ctgggctttt ggatgaggcc aagtggctgt ttgaccattc ccctaatgta
    34381 caggctgcta aaggaattgg ctataaggaa ctctttcctt atttccgtgg agagcagacc
    34441 tttgaggaag ctcgtgagag tcttaaacag gcgacccgtc gttttgccaa gcgtcagctg
    34501 acctggttcc gtaatcgcat gcaggtcacc ttttatcaga ttggagaatc tggtgtacaa
    34561 gaccgcattt taagccagat agaggagttt ttagatgatt gaaacggaga aaaaagagga
    34621 gcgagtcctg ctgattggtg tggaattgca gggtatggac agttttgacc tctccatgga
    34681 agaattggct agtttagcga aaacggcagg ggcagtcgtt gtagatagct acagacaaaa
    34741 acgtgaaaaa tatgattcca agaccttcgt cggctctggt aagttggaag agattgcgct
    34801 tatggtggat gcagaagaaa tcactactgt catcgtcaac aaccgtctga ccccaaggca
    34861 gaatgtcaat ctagaggaag ttctgggtgt taaggtcatt gaccgtatgc agttgatttt
    34921 ggatatcttt gccatgcggg ctcgaagcca tgaagggaag ctccaagtcc acctagccca
    34981 actcaaatac ctcttgcctc gcttggttgg tcaggggatt atgctcagcc gtcaggcagg
    35041 gggaattggt tcccgtggtc ctggtgaaag ccagctggag ctgaaccgtc gtagcgttcg
    35101 caatcaaatc acggatattg agcgccagct caaggtggtt gagaaaaatc gtgcgactgt
    35161 cagagaaaaa cgtttggagt ctagcacttt taagattggt ttgattggtt atactaatgc
    35221 tgggaaatca actatcatga acatcttgac cagtaagacc cagtatgaag cagatgagct
    35281 ctttgcgact ctggatgcga caaccaagag tattcatctg ggaggcaatc tccaagtaac
    35341 tttgacagat accgttggct ttatccaaga tttgccgaca gagttggtgt ccagtttcaa
    35401 gtcaaccttg gaagaaagca agcatgtgga ccttctggtt catgttatcg atgctagcaa
    35461 tccttaccac gaggagcatg aaaaaacggt tctctccatc atgaaagacc tggacatgga
    35521 agatattcct cacttgacgc tttataataa agcggatttg gtggaggatt tcacgcctac
    35581 ccaaacgcca tataccctca tttctgccaa gtctgaggac agtcgtgaaa acttgcaagc
    35641 attattgcta gataagatta aggaaatttt tgaagcattt accctgcgag tgcctttttc
    35701 aaagtcctac aagattcatg atttagagag tgttgcaatt ctggaagaac gtgattatca
    35761 ggaagacggc gaagtgatta caggctacat ttccgagaaa aataaatgga ggttagaaga
    35821 attttatgac tgatattaaa actttggctc taaagtatgg aggttataca agtctggaca
    35881 aggtctatct ggatcagctt ctagctggta aaacagagca ggagcagtta acacttatta
    35941 cacctccgcc aagtgttgtt aatgcctact ttgcagaact ctatcagaaa aagagtcctc
    36001 aggctgcgac ggattatttt gcagaactca gtcaggaact gaatctttac aatactgagc
    36061 caagtttcac cctagaaaat aagcctttta ttcggcttaa tctgtctggt aaatcctttg
    36121 gtttttgtta tgagagtgac ggccttggtc ggattttctc tgaaaatgag gagaaaatct
    36181 cggatgactt gctctttgaa attgcgcaaa ttttccccca tcaattagtc tttgaagagt
    36241 ctggtaagat ttacatgaag cctgtcgagg acgaggaagt tgtcagccta gaaagtctca
    36301 cagctttgac tgatttggaa agattggctg atggtcgaaa acgtctcaaa ggctacagcc
    36361 aagaggattt attgcaagaa gctgctgctt tttctggcaa acgctatttc cgatcggaaa
    36421 accgcacagc catgttatat attgattaat tagaaagtat cgaatggata ttcaattttt
    36481 aggaacgggg gctggtcagc cctctaaagc ccgcaacgtt tcaagtctcg ccctgaaact
    36541 tttggatgag attaacgaag tttggctctt tgactgtgga gaaggtacgc aaaatcgcat
    36601 tctggaaacc acaattcgac cacgtaaggt cagcaaaatc tttattaccc atctgcatgg
    36661 agaccacatt tttggtttgc caggtttcct ttctagccgt gcctttcagg ccaatgaaga
    36721 gcagacagat ttggaaatct acggacctca aggaatcaag tcatttgtct taaccagcct
    36781 tcgtgtgtca ggttctcgtc tgccctaccg cattcatttc catgagtttg accaagattc
    36841 tctgggtaaa attcttgaaa ccgataaatt cactgtgtat gcagaggagc tggaccacac
    36901 tattttctgt gttggctatc gtgtcatgca aaaggatcta gaagggacgc tggatgctaa
    36961 aaaactcaag gctgctggtg ttccgttcgg cccgcttttt ggtaaaatca aaaacggcca
    37021 ggatcttgtt ttggaagacg gaactgaaat caaggcagca gactatatct cagcgccacg
    37081 tccaggtaag attatcacta ttttaggaga cactcgaaaa acggatgcca gtgtgcgtct
    37141 ggctgtcaat gcagatgtcc tagttcatga gtccacttat ggcaagggtg atgaaaaaat
    37201 tgctcgtaac catggtcact caactaatat gcaagctgca caagtagcgg tagaagcagg
    37261 tgccaaacgc ctcctactca accatatcag tgcccgtttc ctctcaaaag atataagcaa
    37321 actcaagaaa gacgctgcca caatttttga aaatgtccat gtggtcaaag acttggaaga
    37381 agtggaaatc tagcagtcac agaaaggata agtatgccta ctattctcat taccggagct
    37441 agcggtggtc tagctcaaga aatggtcaaa ctcctgccca atgaccaact catcttgctt
    37501 ggtagaaata aggaaaaatt agcccaactc tacggaaatt attcccatgc agaattgatt
    37561 gaaattgata ttaccgacga ttcagcccta gaagctctgg taactgatct ttatctccgc
    37621 tatggcaaga ttgatgtctt gattaacaac gctggttacg ggatttttga gggatttgac
    37681 caaattgctg ataaagacat tcaccagatg tttgaggtca atacctttgc cctgatgaat
    37741 ctgtctcgtc accttgcggc tcgtatgaag gaaagcagca aagggcatat catcaacatc
    37801 gtcagcatgg caggtctaat agctactggc aagtctagtc tttactcagc gaccaagttt
    37861 gcggctattg gtttttcaaa tgctctgcga ctcgaactta tgccctatgg agtctatgtg
    37921 acaacagtca atccaggtcc aatccgaaca ggattttttg accaagctga cccagatgga
    37981 acttatctta aatcggttga ccgcttcctc ttagaggcag atgcagtggc taaaaagatt
    38041 gtcaagatta taggcaaaaa taaacgagaa ctcaatctcc cgattttgtt gaacctagcc
    38101 cataagtttt atactctctt tcccaagcta gctgataagt tggcagggga aacttttaat
    38161 tataagtaaa aagaaccaat gtgcaggttg ttgctagcct acatattggt tcttatcatt
    38221 tctcaactat caaactgaac ttcttctagt agatagtcga taaagcgttc gcccatctta
    38281 gataggctgg ttttctcatg ctggatatag accagctcaa tcgggtcatc aatatccagt
    38341 gggatagaaa caatattgtc tccgtttagg ttgctgttca aaatccctgt cgcaatggta
    38401 taaccatcca aaccaatcaa gagattaaag agggtggcac ggtcactgac cacaatggat
    38461 tttttgtggt gttcttgaga aagaatctct tctgaaaagt agaaggagtt gtgcgtccct
    38521 tggtcatagc tgaggtaagg gaaattctcc aaatcagaca gtttcacctt gtctttcttt
    38581 gccagagggt tggtcttgct gacaaagata tgcggttgcg ctgtgaagag atggtgggct
    38641 agcaggtgat tgtcatccag catcttggtt aaaacatcac ggttgtaact gtttaagaag
    38701 aggaccccga cctcactgcg gaagttcttg acgtcgtcga taatctccca agtccgagtt
    38761 tcacgaagga agagttcgta tttctccata tcgcttttct tgagcaaaga gacaaaggca
    38821 ttgaccacaa aggcatagtg ttgagacgaa acgctaaaga gttcgcggtg ggcgacagga
    38881 tttttatagc gttcctccag aagctgggtc tgctcgacaa cctgacgggc ataagagaga
    38941 aactccatcc catcacgggt caaggtgatt cccttgggat tgcggataaa gatctcaatg
    39001 cccatttcat tttccaaatc tcgcactgca ttggagagac ttggctgagt gataaagagt
    39061 tgcttggctg cctcattcat ggagccagtt tcgacgattt tgataatata atgtaattgt
    39121 tgaattctca tgtttttatt gtaccatact tgccttagaa tcgctaaaga agataggaaa
    39181 ataaggagca ttgtgtgagt ctcttcttga aaaaaacaca aaattttgct agaatgagtc
    39241 ttatgaaaac attctatgat gtgcagcaat tcctcaaacg atttggtatt attgtttaca
    39301 tgggaaaacg cttatatgat attgaactga tgaagttgga actatctcgg atttacgatg
    39361 cagggttgat ggataaatta gactatctag aggcagaagc agttcttcgc agagagcaca
    39421 aggtagaatt ggattatatt gagaaaaatg gagaaaagaa ctaatggtta cttggatttt
    39481 gtgggcactt atactagcaa tgttggcgtg gatgggcttt aactatcttc gtattcgccg
    39541 tgcggctaaa attgtggaca atgaggagtt tgaagccttg attcgtacgg gtcaattgat
    39601 tgatttgcgc gacccagcag aattccacag aaaacatatc cttggtgcac gcaatattcc
    39661 ttcaagtcag ttgaaaacta gtcttgcagc ccttcgtaaa gataaacctg tccttctcta
    39721 cgaaaaccaa cgtgcgcaac gagttacaaa tgcagctctt tacttgaaaa aacaaggttt
    39781 ttctgagatt tatatccttt cttatggctt ggattcttgg aaagggaaag tgaagactag
    39841 ctaaccttat ttccaaatta gtcgaatgat aggatgaaga tattgtttta tagtataatt
    39901 aatttgtata aaatttaagg agttcttaga acatgaaaga aaagaagaaa aatccacttt
    39961 ttgtgggtat cttgtcgatt attcttggtt tgttatttcc aattgtaggc ctgattttgg
    40021 gtatcatagg attggtctta gctatttcat accaaaaaga gtcacaatta gactataaaa
    40081 tagaaaagat tcttaatatc ttaggaattg tgatttctgt agttaactgg attgtagcaa
    40141 tcgccttaat ttttcgataa ataaaagaaa aaagctttag ttttaaagct ttttttgttt
    40201 tatcgactca tctctaaata gtttttaatg atttgtaact ctttttggtt caaagggcgg
    40261 tagttacctt ctgctaaatc tgggttcaat gtgaagtccc caaattggat tctcttgagg
    40321 ctagtcacct taataccaac cgagaggaac attttcttga tttgatgaaa ttttccttct
    40381 gaaatggtga tagaggcttg actgatggag ggacttgcag atagaatctc tagttttgcg
    40441 ggtttacaga cagtaccatc taaaaagaca attccctttt gaaaggcttg gatatggtca
    40501 ggtgttagaa gtccattaac ctcaacttga taagtcttat cgacatgata ttggggatgg
    40561 aggagttgga agcccaaggg accgttatcg gtcaagagaa ggagtcctgt tgtatctcgg
    40621 tccagtcggc cgacggcata gagcttgtca gactggatgt cagatggaag caggtccatg
    40681 acggtcggaa gttccttgtc tttgttggct gtaacgacac cagcaggttt atgaagcata
    40741 agataggtgt gttcatagcc ttgaatgatt cgatcctgaa aaaggagttc ttgtagtcct
    40801 gtatcgatat tttgagctag ggagcgggct gggcaaccat cgactagaat ttcccctctg
    40861 aggagtgctt gtttcatggc ctttcggctg attttttctt gagctaataa attatctaaa
    40921 cgcatactgt gcctatctta tcataagtcg cttgctttga aaaggcttga cgtgaaaaga
    40981 aaagcggagt gaaaacattt acacttgctt gagttatgtt atttatttga aattatggta
    41041 taatcgttca gttagaaaat aaattttgaa tattatagag gaaatcatga caaaattaag
    41101 agaagatatc cgtaacattg cgattatcgc ccacgttgac cacggtaaaa caaccctcgt
    41161 tgacgaatta ttgaaacaat cagaaacgct tgatgcacgt actgaattgg cagagcgtgc
    41221 tatggactca aacgatatcg aaaaagagcg tgggattacc atccttgcta aaaatactgc
    41281 cgttgcttac aacggaactc gtatcaacat tatggacaca ccaggacacg cggactttgg
    41341 tggagaagtt gagcgtatca tgaaaatggt tgacggtgtt gtcttggtcg tagatgccta
    41401 tgaaggaacc atgccacaaa ctcgtttcgt attgaaaaaa gccttggaac aagaccttgt
    41461 cccaatcgtg gttgttaaca aaatcgataa gccatcagct cgtccagtag aagtagtgga
    41521 tgaagtcttg gaacttttca tcgagcttgg tgcagatgac gaccagcttg atttcccagt
    41581 ggtttatgct tcagcgatca acggaacttc ttcattgtca gatgatccag ctgaccaaga
    41641 agcgactatg gcaccaatct ttgacacgat tatcgaccat atcccagctc cagtagataa
    41701 ctcagatgag cctttgcagt tccaagtgtc gcttttggac tacaatgact tcgttggacg
    41761 tatcggtatc ggtcgtgtct tccgtggtac agttaaggtt ggggaccaag ttaccctttc
    41821 taaacttgac ggtacaacta aaaacttccg tgttacaaaa ctcttcggtt tctttggttt
    41881 ggaacgtcgt gaaatccaag aagccaaagc gggtgacttg attgccgttt caggtatgga
    41941 agacatcttt gtcggtgaaa ccatcactcc gacagatgca gtagaagctc ttccaatcct
    42001 acacatcgat gagccaactc ttcaaatgac tttcttggtc aacaactcac catttgctgg
    42061 taaagaaggt aaatgggtaa cctctcgtaa ggtggaagaa cgcttgcagg cagaattgca
    42121 aacagacgtt tcccttcgtg ttgacccaac tgattcacca gataaatgga ctgtttcagg
    42181 acgtggagaa ttgcacttgt caatccttat cgaaacaatg cgtcgtgagg gctatgaact
    42241 tcaagtatct cgtccagaag ttatcgtaaa agaaatcgac ggtgttaaat gtgaaccatt
    42301 tgaacgtgta caaatcgaca ctccagaaga ataccaaggg tctgttatcc aaagcctttc
    42361 tgaacgtaaa ggtgaaatgt tggatatgat ttcaactggt aatggtcaaa ctcgtttggt
    42421 cttccttgtt ccagcgcgtg gtttgattgg atactcaact gagttcttgt caatgactcg
    42481 tggttacggt atcatgaacc ataccttcga ccaatacttg ccattgattc caggggaaat
    42541 tggtggacgt caccgtggtg cccttgtttc tatcgatgct ggtaaggcta caacttactc
    42601 aatcatgtct atcgaagaac gtggtacgat ctttgtcaac ccaggtactg aggtttatga
    42661 aggaatgatc atcggtgaaa actctcgtga aaatgacttg acagttaaca tcacgaaggc
    42721 aaaacaaatg accaacgttc gttcagctac taaggaccaa acagctgtta tcaagacgcc
    42781 tcgtatcttg acacttgaag agtctcttga gttcttgaac gacgatgagt acatggaagt
    42841 aacgcctgag tctatccgtt tgcgtaaaca aatccttaac aaagcagagc gtgagaaagc
    42901 taacaagaag aaaaaatcag ctgaataaga gctagaaaga gagaaagatg gtctatttag
    42961 tcctaggaat tttactgctc ctactctatg tatttgcgac accagaaagc attaaaggga
    43021 ctgtcaatat cgtcgctatg gtatgtattt tagtggcact cttgatttta ttggttctat
    43081 cttttctgaa aatttttcaa ttaccaacag aaatattcct agcaatagcc atgttgatcc
    43141 tagcttactt tagtgttaga gacatcacac tcatgccagt caaaaaaagt aaaagaagat
    43201 aaaaaagaga gtttcggctc tctttttgct aggaatttta caatagtttg aattgctttt
    43261 tagttaacac catctctttt acttgtatag tatgaatggg aaaaacttga ataaaattcg
    43321 ttaatggcat ctattttata tttggttagt actggttgca tattattttg aaataaaact
    43381 actatataat attattcaca gaggtaatat agtaaaatat ctaaaaaatt cgattttttc
    43441 cttgacaaca aataataaaa atgttattct tatcacataa gaaatcggtt tcaaaaaaga
    43501 gagaggagga tttattttgt tgcattgttg ctcagggtgt gctttttttg aaagaaaaaa
    43561 taaaatgaaa acgaaaaaac atagattact tgctctagct cttatttcaa gctttacatt
    43621 attgggagct gcatcagctg ctgtacaata tccagatgga ggagtatgga catatggaga
    43681 aggttcagga ggtggttggg ctttttcaaa ttactatcat ggtaaaaaat atcattattc
    43741 ttctgttgta agtaaatggg atagtcattc agataaagga tcagcacctg cagggaaaac
    43801 ttcagaggct tggatttgga ctaaatttgg ggaacaagta tcattttact atgactatga
    43861 ctaatattta gttttcttag ataattcccc ttgtaagaaa ttacaggggg aattttgttt
    43921 acaaggagtc tactatgaag aaactattca tattactatc aacttttttt ctcagcttct
    43981 tctttgcttg gattattgtc ttacgtgcgc cacaatattt atatgcaagc tatgattccg
    44041 ttactttact tcgtgtcaaa aaagaggctc aggaaccgac tcgtgaggta tttgaacagg
    44101 aattggagaa gtttgtaaac tcagaacaga gtttaatagc taggagaatt gtagaaccga
    44161 gtaaggatgg gacgactcac tttacttatg caacttatgg tcagggaaca ttaccaaaac
    44221 aattccaaga agctagccaa gaaagtcgtg aacgtagtga tccgctaaat agttatctcc
    44281 ttttatcagg ctccttgaca aaagaaaagc tagctgataa attaggagat ttaggttata
    44341 aagcaattgc tgaccgaaag acaccgccct attttcttgc ttttcgaata ttactaaatc
    44401 cccttatttt aattagttta gcaatatttg gcttatcttt ctttgcttta gtgattatca
    44461 ctcggattaa ggaaatgaga gcagcaggta taaaactctt ttctggtcag actctcttat
    44521 ccattatggg gcattcttta tctactgata ttaagtggct ccttctatca gccctccttt
    44581 ccttcctagg tgggggagtc gttcttttta gtcaaggttt gttttatcct atcttgttag
    44641 ccacctatgg ttttgggatt agtttctatc tgttgttttt attggcgatt tcaattttac
    44701 taatgctcct ttatctaatg agtttgagtt acaaagcatt agttcccgtt attaagggaa
    44761 gattacccct taaacgcctg atgattttaa ccctattgtg tcagttggtt gctgtcttta
    44821 cagtgggata cgctgttaag acaggtttga cgtcttacca acgattgaaa gaacttgaaa
    44881 tttcaaaaca agcatggcat gacagagtag actattatca aatttctttt ggcttaggtg
    44941 acagagtaaa tgatacagaa aatcagaata agtggtatga attttccaaa gaagcagttg
    45001 aaaaagaaca ggctctattt gtaaaagaga atctcattca ttttgcaaat cctcaaggaa
    45061 aaaatgaaaa cggggaaaca ctggatacct atagtccaga tgctaatgtt ctctatgtga
    45121 gtccaagtta tttagacaag gaaaatgtgg ctgtaaatga tgagactaga cagaaactag
    45181 ctcatcttca aaaaggggaa tttggactct tattaccaga atctcttcgt tcacaggaag
    45241 cagaacttaa gaaagttttt gaagaacgtt tgaactatta cggaaaatca agcgaggata
    45301 aagacgctcc tttagagtat gaaatgagag cgattgttag ctatcttcca acaggacaaa
    45361 aacgctttgt ttataataac ggtgaaagtc cagtatctat tcagtactta accgatccga
    45421 ttttagttgt atttactcca acatctacag gtgatagttt catttcaaaa tatgtttggt
    45481 ctatcaatgc tggaaaacaa ctctttatca aaggatatga gagtgggcta gaactcttaa
    45541 agaaagctgg aatttatgag caagtatcct atcttaaaga aggaagaagt gtttatctaa
    45601 ctcgttataa tgaagttcaa actgaaacag caactttaat cttaggagct attgttggga
    45661 tagccagttc cttattactc ttttattctg tcaatcttct atatttcgag caattccgcc
    45721 gagatatctt gattaaacga atttcaggtt tacgattttt tgaaacacat gctcagtata
    45781 tggttagcca atttgccagt tttgtatttg gtgctagttt ctttatttta agcagtcgag
    45841 acttggtgat tggcttgctc actttattcg tctttctagc tagtgcagtt ttgacgcttt
    45901 accgtcaagc acagaaagaa tctcgtgttt ctatgacaat tatgaaagga aaataggatg
    45961 attgaactaa agaatatatc taaaaaattt ggaagccgtc agctattttc agatacaaat
    46021 cttcattttg aaggtgggaa aatttatgcc ttaatcggta caagtggctg tggtaagaca
    46081 acactcttga atatgattgg acgattagag ccatatgaca aagggcaaat catctatgat
    46141 ggcacttctc ttaaggacat caagtcttct gttttcttta gagattactt gggatactta
    46201 tttcaagatt ttggcttaat tgaaagccaa accgtcaaag agaatctcaa tctgggttta
    46261 gttggtaaaa agttgaagga aaaagagaaa atctctttga tgaaacaagc tctaaaccgt
    46321 gtaaacctct cttatttgga tttgaagcaa cctatatttg agttatcagg aggagaagca
    46381 caacgtgttg cattagcgaa gataatttta aaggatccgc ctttgattct tgcagatgaa
    46441 ccaaccgctt ccttagaccc caaaaactct gaggaattac tttccatcct agaatcttta
    46501 aaaaatccga atcggaccat tattattgcg acccacaatc ctctgatttg ggagcaagtg
    46561 gatcaggtca ttcgagttac cgatttatca catagatgat atggtaagat tcagttagaa
    46621 gaaagagtca caaacacact ttgtggcttt tttatttcca taaaaatggt aaaatagtag
    46681 gagtagaaat ggagttcgag acatgaaagt aatagatcaa tttaaaaata agaaagttct
    46741 tgttttaggt ttggccaagt ctggtgaatc tgcggctcgt ttgttggaca agttaggtgc
    46801 cattgtgaca gtaaatgatg ggaaaccatt cgaggacaat ccagctgccc aatgtttgct
    46861 ggaagaaggg atcaaggtca ttacaggtgg ccatcctttg gaactcttgg atgaagagtt
    46921 tgccctcatg gtaaaaaatc caggtatccc ctacagcaat cccatgattg aaaaggcttt
    46981 ggccaaggga attccagtct tgactgaggt ggaattggct tatttgattt cagaagcacc
    47041 gattattggt atcacaggat cgaacggtaa gacaaccaca acgactatga ttggggaagt
    47101 tttgactgct gctgggcaac atggtctttt atcagggaat atcggctatc ctgccagtca
    47161 ggttgctcaa atagcgacag acaagaacac gcttgttatg gaactttctt ctttccaact
    47221 catgggtgtt caagaattcc atcctgagat tgcggttatt actaacctta tgccaactca
    47281 tatcgattat catggattat ttgaggaata tgtagcagcc aagtggaata tccagaacaa
    47341 gatgacagca gctgatttcc ttgtcttgaa ctttaatcaa gacttggtaa aagacttggc
    47401 ttccaagaca gaagccactg ttgtaccatt ttcaacactt gaaaaggttg atggagctta
    47461 tctggaagat ggtcaactct acttccgtgg tgaagtagtc atggcagcga atgaaatcgg
    47521 tgttccaggt agccacaatg tggaaaatgc ccttgcgact attgctgtag ccaagcttcg
    47581 tggtgtggac aatcaaacca tcaaggaaac tctttcagcc ttcggtggtg tcaaacaccg
    47641 tctccagttt gtggatgaca tcaagggtgt taaattctat aacgacagta aatcaactaa
    47701 tatcttggct actcaaaaag ccttgtcagg atttgacaac agcaaggtcg tcttgattgc
    47761 aggtggtttg gaccgtggca atgagtttga cgaattggtg ccagatatta ctggactcaa
    47821 gaagatggtc atcctgggtc aatctgcaga acgtgtcaaa cgggcagcag acaaggctgg
    47881 tgtcgcttat gtggaggcga cagatattgc agatgcgacc cgcaaggcct atgagcttgc
    47941 gactcaagga gatgtggttc ttcttagtcc tgccaatgcc agctgggata tgtatgctaa
    48001 ctttgaagta cgtggcgacc tctttatcga cacagtagcg gagttaaaag aataaaatat
    48061 gaaaaaaatt gtctttacag gtggggggac ggttggacac gttaccctca atcttttgtt
    48121 aatgcccaag ttcatcgaag atggttggga agtccactat atcggggaca agcgtggtat
    48181 cgaacaccaa gaaatcctta agtcaggttt ggatgtcact ttccactcca ttgcgactgg
    48241 aaaattgcgt cgctatttct cttggcaaaa tatgctggac gtcttcaaag tttgctgggg
    48301 aatcgtccaa tcgctcttta tcatgttgcg acttcgtcca cagacccttt tttcaaaggg
    48361 gggctttgtc tcagtaccgc ctgttatcgc tgcgcgtgtg tcaggagtgc ctgtctttat
    48421 tcacgaatct gacctgtcta tgggcttggc caataaaatc gcctataaat ttgcgactaa
    48481 gatgtattca acctttgagc aagcttcgag tttgtctaag gttgagcatg tgggagcagt
    48541 gaccaaggtt tcagatcaaa aaaatccaga accagatgaa ttggtggata ttcaaagcca
    48601 ctttaatcat aaattgccga ctgtattgtt tgttggcggt tctgcaggtg ctcgtgtctt
    48661 taaccaattg gtgacagacc ataagaaaga actaacagag cgctacaata ttatcaatct
    48721 aactggagat tctagcctga atgagttgag ccaaaatctt tttcgtgttg actatgtgac
    48781 cgatctctat caacccttga tggaattggc tgatattgtt gtgacacgag gtggtgccaa
    48841 tacgattttt gagctcttgg cgatagcaaa attgcatgtc attgtgccgc ttggtcgtga
    48901 agctagtcgt ggtgaccagc ttgaaaatgc agcttacttt gtaaaaaaag gctatgcaga
    48961 agaccttcaa gaaagcgatt tgaccttgga tagtttggaa gagaagcttt ctcacttact
    49021 aagtcacaag gaagattacc aagctaagat gaaggcttct aaggaattga aatctctagc
    49081 agatttttat caattgttga aaaaagattt atcataagga aagtaaatgt caaaagataa
    49141 gaaaaatgag gacaaagaaa tcctcgaaga attgaaagag ttatcagaat ggcagaaacg
    49201 aaaccaagaa tatctaaaaa agaaggctga agaagaggcg gctctagctg aggagaagga
    49261 aaaggaaaga caagctcgaa tgggagaaga atctgagaag tcagaggaca aacaggacca
    49321 ggagagtgaa acagaccagg aagattcaga atcagctaag gaagagtctg aagaaaaagt
    49381 agcatcctca gaggctgaca aagagaaaga agagaaagaa gaaccagagt ctaaagagaa
    49441 ggaggaacag gataaaaagc tttctaaaaa ggctacaaag gaaaaaccag ccaaagcaaa
    49501 gattcctggt atccatatct tgcgagcatt cacgatttta tttccaagtc tgcttttatt
    49561 gattgtctct gcctacttgc tcagtcctta tgcgaccatg aaagatattc gtgttgaggg
    49621 aacggtgcaa actacagctg atgatattcg acaggcttca ggcattcagg attcggatta
    49681 tacgattaac cttctgctag acaaggcaaa atatgaaaag cagattaagt ctaactattg
    49741 ggttgaatca gctcaacttg tctatcaatt tccaactaag ttcactatta aggtcaagga
    49801 atatgatatt gtggcctact atatttctgg tgaaaatcat tatcctattc tttccagtgg
    49861 tcagcttgag actagttctg tgagtctgaa cagtttacca gaaacttatt tatcagttct
    49921 ctttaatgat agtgaacaaa tcaaggtttt tgtctcagaa cttgctcaaa ttagcccaga
    49981 actcaaggcg gctatccaaa aggtggaatt agccccaagc aaggtgacat ccgatttaat
    50041 tcgattgacc atgaatgatt cggacgaagt cttggttcct ctatctgaaa tgagtaagaa
    50101 actgccatat tacagtaaga ttaagccaca attgtcagaa ccgagtgtgg tcgacatgga
    50161 agctggaatt tacagttaca ctgtggcgga taaattaatt atggaggctg aggaaaaagc
    50221 caaacaagag gccaaggaag ctgagaaaaa acaagaagaa gaacagaaaa aacaagagga
    50281 agagagcaat cgaaaccaaa cgacccagcg ctcatcgcgt cgctaggttt actttttctc
    50341 ttatagttat ttagtgacca tgtttttact tgacaagtgc tagtagaaat aatagaataa
    50401 tagaaaacct ttaaagcagt ccagagaggc agctaaggtt agacggtgaa agggtggaga
    50461 ctacccattt ttcgtggaac cttgctgttg gcaggttcct tttttcgtgg cttctgttgg
    50521 tcagactctc tcactagtaa aggtaaaagg agaaacctat gcgagaacat cgtccaatca
    50581 ttgctcttga ttttcctagt tttgaggcgg tcaaggaatt tttagctctt ttcccagcag
    50641 aagaaagcct ttatctcaag gtagggatgg agctttatta cgcagcgggg cctgagattg
    50701 tgtcctactt aaaaggtttg ggtcatagtg tctttttgga tctcaaactt catgacattc
    50761 ctaatacagt caagtcagcc atgaaggtct tgtctcagct tggtgtcgat atgactaatg
    50821 tccatgcggc tggtggtgta gagatgatga aggcggcgcg tgaaggtctt gggagtcaag
    50881 ccaaattgat cgctgtaact cagctcacat caacgtcaga agctcagatg caggagtttc
    50941 aaaatatcca aaccagtctg caagagtctg tgattcacta tgccaagaag acagctgaag
    51001 ctggcttgga tggtgttgtt tgctcggctc aggaagtaca agtcatcaag caggctacca
    51061 atccagattt tatctgtctg acaccaggga ttcgtccagc tggtgttgca gttggagatc
    51121 aaaaacgagt catgacacct gctgatgcct atcaaatcgg cagtgactat atcgtagtgg
    51181 gacgtcccat tacccaagct gaggatcctg ttgcagctta tcatgccatc aaggatgaat
    51241 ggacacagga ctggaattaa agaactagat tagaaaaata aaaggagaat accatgacac
    51301 ttgctaaaga tatcgctagc cacctcttga aaatccaagc cgtttacctc aaaccagagg
    51361 aacccttcac ttgggcatct ggtatcaagt caccgattta cactgataat cgtgtgacac
    51421 tagcctatcc agaaactcgt accctaattg aaaatggttt tgtggatgct atcaaagaag
    51481 cctttcctga agtagaagtg attgcaggaa ctgcaacagc agggattcca cacggagcca
    51541 ttattgctga taagatgaac ttgccttttg cctacatccg tagcaaacca aaagaccacg
    51601 gagctggtaa tcaaatcgaa ggtcgcgtag ctcaaggtca aaaaatggta gtggttgaag
    51661 accttatttc aacgggtggt tcagttcttg aagctgtagc agcagccaag cgagaaggag
    51721 cagatgtact tggagttgta gcgattttca gctaccaatt gccaaaagca gataagaact
    51781 ttgcagatgc tggtgttaaa cttgtgacgc tttcaaacta tagcgagctt atccatctag
    51841 cccaagaaga aggttacatc acgccagagg gccttgatct tctaaaacgc tttaaagaag
    51901 accaagaaaa ttggcaagaa ggttaggtca gtaagataaa gagagacgag gctaccgagt
    51961 ctcttttacc attttattta aaatatgaca atattttaaa taaaataatt gacaacgctt
    52021 tcttttattg atataatgaa aatgtaatat gtatcaaatt gatcaatcaa ctatcttgtt
    52081 tatcacttct taagaggacg atgtcatgaa aagaagaaaa atatattcct tttttgcgta
    52141 gttacaattg catctagttt gtttctccct acagttttag ctagacagat tggaaattat
    52201 gatttaacgt tgccgcgttg gggttcggat acaactagtg agcttgagaa agaaaacgcc
    52261 tctgctggaa ttaataatag tgacagcact ggtggcggta aaaggttaag tacctctatt
    52321 cgtagcgcct atagtgggtc agatattacc ccggtatatt cattggggtc tggctctagg
    52381 attgtcatgt actataatgg aggtggtgac aattatattg gttctggtac tagattagct
    52441 atggcgccac aatttggaaa tcatgtaaga attcatactt caggttcttg gagtccagat
    52501 tcttattaac ttacttgtca gagtaagcct taaagatggt tgattgtggg tgtagcatga
    52561 aaaaagaatg ctacacccta tttttattat aaggaggagt aaggatggaa tttttcattt
    52621 gtaatcttgt acgagtcgtt caatcacctc gattttatat gtctttattt ttgacccttc
    52681 tttgcatgag tttaggaaat ttccttgctt tcaatggtat ttataaaatt gaaggtttat
    52741 cgattttttt tgccgcttct tctattcgag gattttcacc gattagccta gtagctgcac
    52801 ttatctgtac actgccctat tctagtcaga taatagagga tgctgagagt cattttctaa
    52861 cagcacaatt gtgccgaatt tctaaaaaga ggtatctagc tattgtaggt agtactgcaa
    52921 ttatttcttc ttttctagtc ttttttctcc cctatttatt attattagga attaatcttt
    52981 tagtgactcc ttatcaggaa atttatattg gagcttatag tggtgcctta aaagaattat
    53041 ttgattctaa tcagttgctc tatagtcttg tgacgactct ttggtatgga gtttggggcg
    53101 ctgtgttctc tatttttgga ctagctagtg ctttgctagt gaagaaaaaa ataggagcta
    53161 ttttcatccc agttacctat atgatggttg gtggtatttt ttgggctatt ttagggctat
    53221 cttacttaga acctgtgaca acattagctt tgggatatca gaaagatatc agtctttcct
    53281 tagttagtgg gcatcttgct tttattttat ttgttagttg tttggttgtt tatggtacat
    53341 tttttctaca ttcagaggac tatgtataat gaaacaattt gttcaatttt ataaaaaaga
    53401 tttcttagca gtattggttt attttatatt actgctatcc tgtgttttat ctagtacagt
    53461 atatttattg cgctgtcgcc aatattcaat ccatccaaat gtattagaat ggatcttagt
    53521 tttacttcaa gatatgacga ctggagtata ttgctttccg ttcacatata tattgttctt
    53581 tttttatttg atgaataact attttaatag gttggagtgt cgcattcgtc tgaaatcaat
    53641 taagcacttt accagtttta gtttcaaatt agcagctctt agtacgggga tttggacggc
    53701 gattttattt ttattgattt ttctaattgc atttagtaat ggttttagct tctctttgga
    53761 gataaaggag gttgattttt taagagaatt ttatggtata agtattgcaa acaatgctag
    53821 tttctttata ggattttttt ctcttatata gcatactatt tctttttatc cttacttact
    53881 attagcagtt tttcttggtt taaaaaatca aacatgagct tagtatttct gtttactttt
    53941 ttatttgtag aatccttatt ctggatttat cagttgaaca atgggataat tggattattg
    54001 ccaatttttc agtatatggt aaattccaat ccgtatgcat tgatttattg gcttacatta
    54061 ctatctatca taattccatt gactgtattt tctgttcata gaaactggag gagagtgtaa
    54121 aagttggaaa tgggaaagtt aagtagtcac atgtggaggt tgaatcagat aatctatacc
    54181 aagtactttt ggggttatgt tcttttttgg atattgattt gtttaggatt atggtattgg
    54241 ttagaaggaa atgatagact tgttatagaa attttaaaag ggcctaatct gagtcaaaac
    54301 tcttttttag tcttatctat atggttgctt cattggttta ttattcatac attttttcta
    54361 gcagttgtat atcgtagaag agcatccgat ttctttatgg aagtgattcg attttcttct
    54421 attaagctct ggattaggta tcagatttgg acctgttttc tttatggact cattttaatc
    54481 atggtaaaag ttctagtgat tcaatttatg ttacagttac caaactggga tataggagtt
    54541 ttgtttatag ttgattcttt gaatgcttgt gtgttagtct tgttttgctt tatgttatac
    54601 gcactaggag cgaatgtaca aatgaacttt gcttgcgtta gtttcttttt actcatgatt
    54661 gtgtttggtg gtctatttgt aggaaatcga actaattatc tattttatat tttgaatcga
    54721 gggaatggag atataggacg agatttattt cttcagttgc tatttttagt ctttcttttt
    54781 aaaagtattt tctatttcac tcgtcaaaag aggaggttta tagaatgaat gaaataatca
    54841 tattaaaaaa tattgagttg aaattaaaaa aaacatgtgt ttttcaaaac cttaatttta
    54901 gttgtaaaca gggggaaatt ataggaatta ctggtgcgaa tggctcaggg aaaagtgtat
    54961 tgtttaaatt aatagctggt ttatatagtc cgtcttatgg agaagtgtta atcaatgggg
    55021 aaaatattgt tcctgagaga aaaattccag ctaatttggg agctttgatt gaagaacctg
    55081 gttttataaa ttattatagt ggctttaaga atttacaata tttggcaagc atacgaggag
    55141 tagttggtaa tcaggaaatc aatgatacac tgaaaatagt tggtctatat gagcaaaaag
    55201 accagaaagt taaaacttat tcgctaggta tgaggaaaaa gctagggatt gctcaagcaa
    55261 ttatggagaa tccctctatt cttttactag atgaacctat gaatgccttg gataaatcaa
    55321 gtgtagaaaa tatgagaaca ttgtttagaa agctctctag tgaaaaaggg acaacaattt
    55381 tgattgctag tcatagtgaa gaggatattc gtatcttatg tgataaagta tatgcaatag
    55441 aagataaagt atgtacactg tgttcagatt aaacatctta gatagactca ggatgttata
    55501 ggtaaaatct taaaaaggga ttggagctta aaatccagtc ccttttaaga gttaatggcc
    55561 accttcaaca accaggtcat ctgctttagc agcgtcaccg taggttgggt gaagtgtttt
    55621 ttcataggcc ttgtggaaga agttttcctt gcctaatttt tcaatatctt tattgatgaa
    55681 gtctagcaat tcttggttgc ctttttgaac tgctgccgca atggtatcgg gatcaccgag
    55741 ggaagtaatt cctacttcaa atcctttatt ttcaagtgcc caagctagaa cttccgtatt
    55801 gtcagttgaa aaggcatctc cacgtccgtc aagaagagct tggtaagagt cactgtattg
    55861 gtcgtatttt tggagtttga tttctggatg attcttttca aaataagtct cagcagtcgt
    55921 tccttttgtg acaattaagg ttttaccttc aagttgtttg acgtctgtaa tgagaccagt
    55981 cttaggtgat acgacaccca gagaaacttt catatatgga agggcaaaat caacttgttt
    56041 cttacgttcg tcagttactg taaagttagc aagagtaata tctaccttgt ttgaaatcaa
    56101 gtattccgca cggttggcag catcgactga aatgtattta accttgacac caaggtcttg
    56161 agctagttgg ttccctagtt caatatcgta gcgtagcctt ggtaagaacc atcattgtca
    56221 acgtagccaa acggtttttt atctccaaac acggcgattc gcagttcacc gctttttttt
    56281 gatttcatcg atagtgcgag ctttggcagt tgtttttcca gaggatgaac cagcgtttcc
    56341 acctgagcta caagcagtga taaagataag ggcaaaggca agtgctaaaa cagttaggag
    56401 tggtttgaat agtttcataa gaatctcctt tatagatatg agccaaattg gctaaagtca
    56461 aagacgttta aaaattcctg ggctcgtttg gtttgcggat tggtaaagaa ggcttgagct
    56521 gttccttctt cagcgatttt cccttggtcg aggaagataa tccggtcagc aatggcttgg
    56581 gcaaactgca tttcgtgggt tactaaaatc atggtacggc cttcttgggc caaatcattg
    56641 ataagttcca gcacctcacg caccatttct ggatccagcg aagcagtcac ctcgtcaaaa
    56701 aggatgattt ctggatgcat taggagggca cggacaattg caacacgttg cttctgtcca
    56761 ccagataatt gacgggcaaa gctatgttgt ttatccagca aaccgacacg atctagtaat
    56821 tgcaaagctt cttccgttac ttctttcttg tcccatcctt gagttttgat agggcctagg
    56881 atgaggtttt gtaagacatc cagatgggga aagagttcat aactttaaaa gaccatgcca
    56941 atcttttggc gaactaggtg aaaatctttt ttattttcaa cgatagactg accatccaga
    57001 agaatgtctc caccttgaat actttctaag ccgttgaggc aacgaaggag ggtacttttc
    57061 ccacaaccag atggccctag gatgacaaca acttcccctt ttttgatttc tagagaaagt
    57121 ccttggagga tgggattgtc tccgaaggat ttttttagtt ccttgatttc taagatagtt
    57181 tcagacattt agtttctcca atgtttttct aagtgagtgg atagtttgga aatagggtag
    57241 caaactgcga aatataagat tagaatggtt ccataaatcc aaaatgaagc agttgggatg
    57301 gtcaggcgat tgctatcgat gatttgttgt ccaactttgg tcacttccac aaccccaatc
    57361 aaaacaacta atgaagtggt tttaatcatc cgagtgacaa gattgatagc ctgcggtagc
    57421 agtcttctta agacttgtgg gatgatgatg tggtagtaaa gttgaacatt agtcaagtcg
    57481 agtgcctatc cactttcaaa ctgatgttta gggagagaag tgatagctcc acgtaccaag
    57541 tctcccattt cagctgttcc ccagagggta aaaatgataa tagctgaagt ctcacctgag
    57601 atattgatat taaagtttcg agccaagcca aagtaaacga tgaagagtag caccagctgg
    57661 ggcatgatac ggataaattc cagatacaat cgtgttaaaa atcgtatgat tctagaatgg
    57721 gaggtcatga tgattcccat gactgttccg aacatcatgg ataagaggac agacaggatg
    57781 gatatcccaa tcgtaacgcc caacccctgt aagattctca ggagattatt tccttgaaag
    57841 agtacttgga ttcccgaatc ctgcatggcg ggtcctcctt tctatccagc taaagaccag
    57901 tgagatgggt agcagcatga tcagataagc aactaccaac atagctagcg caatgtctgt
    57961 ctcatagtag agaccaatca aatccttggc gacgtacatg aggtcggcca aagccactgc
    58021 tgagaaaaca gaggtttcct tgataaggaa aatgacattg gcactaaagg aggggagtgc
    58081 caccgctgtt gcttgcggaa gaaccacata gcgaaagacc tgtagaggtg tcagaccaat
    58141 agcgaggcca atctcctgct gggtttgact gatggcttcc agcccacttc ggaaagattc
    58201 tgccatatag gatcctccta aaaagacaag cccaagcgtt gcacagactt ctgaagatag
    58261 gacaatcccg attcggggaa gaccgaagta gagaaagaag agttgaatca aaaggggcgt
    58321 attacgtgac aattcaatgt aggctgtcgc tacttgcgcc aaaacaggga ttcgataatg
    58381 tcggatgata ctaacgatta aaccgagcag aaaggatccc aaaattcccc aaactgcaat
    58441 atgcaaggtc agaaagaatg ccttttgata tagtggtaga tattgttcaa caatggacca
    58501 atccaaaaat agaacctccc atctagaaat aatacagtta ttgtagcact taaaatcttc
    58561 tttggataat atctattttt tattgccgtt ataaggattt tttaccatag acataaaatt
//
LOCUS       DAVHSH010000007        55386 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000007 DAVHSH010000000
VERSION     DAVHSH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.007"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(157..966)
                     /locus_tag="VVR08_000536"
     CDS             complement(157..966)
                     /locus_tag="VVR08_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6074495.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHHRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(968..1771)
                     /locus_tag="VVR08_000537"
     CDS             complement(968..1771)
                     /locus_tag="VVR08_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6074496.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1781..3268)
                     /gene="tacF"
                     /locus_tag="VVR08_000538"
     CDS             complement(1781..3268)
                     /gene="tacF"
                     /locus_tag="VVR08_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU6074497.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVGIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3604..4311
                     /locus_tag="VVR08_000539"
     CDS             3604..4311
                     /locus_tag="VVR08_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU6074498.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4316..5338
                     /locus_tag="VVR08_000540"
     CDS             4316..5338
                     /locus_tag="VVR08_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6074499.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5355..6224
                     /gene="licA"
                     /locus_tag="VVR08_000541"
     CDS             5355..6224
                     /gene="licA"
                     /locus_tag="VVR08_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU6074500.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNVVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6214..7092
                     /locus_tag="VVR08_000542"
     CDS             6214..7092
                     /locus_tag="VVR08_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU6074501.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7104..7793
                     /locus_tag="VVR08_000543"
     CDS             7104..7793
                     /locus_tag="VVR08_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU6074502.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7879..8727
                     /gene="dprA"
                     /locus_tag="VVR08_000544"
     CDS             7879..8727
                     /gene="dprA"
                     /locus_tag="VVR08_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU6074503.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            9611..10654
                     /locus_tag="VVR08_000545"
     CDS             9611..10654
                     /locus_tag="VVR08_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU6074504.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEHFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10821..12908
                     /gene="topA"
                     /locus_tag="VVR08_000546"
     CDS             10821..12908
                     /gene="topA"
                     /locus_tag="VVR08_000546"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU6074505.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13129..13488
                     /locus_tag="VVR08_000547"
     CDS             13129..13488
                     /locus_tag="VVR08_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU6074506.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13581..14213
                     /locus_tag="VVR08_000548"
     CDS             13581..14213
                     /locus_tag="VVR08_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU6074507.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14257..14913
                     /locus_tag="VVR08_000549"
     CDS             14257..14913
                     /locus_tag="VVR08_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU6074508.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14932..16026
                     /locus_tag="VVR08_000550"
     CDS             14932..16026
                     /locus_tag="VVR08_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU6074509.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDAQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGCSVSYHDMPSV"
     gene            16038..17075
                     /gene="leuB"
                     /locus_tag="VVR08_000551"
     CDS             16038..17075
                     /gene="leuB"
                     /locus_tag="VVR08_000551"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU6074510.1"
                     /translation="MAKKIVALAGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            17072..17341
                     /locus_tag="VVR08_000552"
     CDS             17072..17341
                     /locus_tag="VVR08_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU6074511.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17345..17704
                     /gene="leuD"
                     /locus_tag="VVR08_000553"
     CDS             17345..17704
                     /gene="leuD"
                     /locus_tag="VVR08_000553"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU6074512.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISLVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17923..18066
                     /locus_tag="VVR08_000554"
     CDS             17923..18066
                     /locus_tag="VVR08_000554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074513.1"
                     /translation="MTSNKAELERKFAAKERKRNKPGVVLCGIMDELRALAQLNPEIE
                     AFY"
     gene            18166..18339
                     /locus_tag="VVR08_000555"
     CDS             18166..18339
                     /locus_tag="VVR08_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074514.1"
                     /translation="MTDVRGTSCFVIKFGKAGEQLAAKLWEEGKMVYASSASMTKRLK
                     LAMRARCNGVYGR"
     gene            18329..18490
                     /locus_tag="VVR08_000556"
     CDS             18329..18490
                     /locus_tag="VVR08_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074515.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            18653..20584
                     /locus_tag="VVR08_000557"
     CDS             18653..20584
                     /locus_tag="VVR08_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU6074516.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELELSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            20571..21887
                     /locus_tag="VVR08_000558"
     CDS             20571..21887
                     /locus_tag="VVR08_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU6074517.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            22062..23048
                     /locus_tag="VVR08_000559"
     CDS             22062..23048
                     /locus_tag="VVR08_000559"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU6074518.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            23112..23183
                     /locus_tag="VVR08_000560"
     tRNA            23112..23183
                     /locus_tag="VVR08_000560"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23145..23147,aa:Arg,seq:ccg)
     gene            23366..24064
                     /locus_tag="VVR08_000561"
     CDS             23366..24064
                     /locus_tag="VVR08_000561"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU6074519.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            24055..27594
                     /gene="smc"
                     /locus_tag="VVR08_000562"
     CDS             24055..27594
                     /gene="smc"
                     /locus_tag="VVR08_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU6074520.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            27591..28385
                     /locus_tag="VVR08_000563"
     CDS             27591..28385
                     /locus_tag="VVR08_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6074521.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLAITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGNHKERSVIAYMEGL"
     gene            28385..29203
                     /locus_tag="VVR08_000564"
     CDS             28385..29203
                     /locus_tag="VVR08_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6074522.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            29207..30484
                     /gene="ftsY"
                     /locus_tag="VVR08_000565"
     CDS             29207..30484
                     /gene="ftsY"
                     /locus_tag="VVR08_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU6074523.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(30530..32017)
                     /locus_tag="VVR08_000566"
     CDS             complement(30530..32017)
                     /locus_tag="VVR08_000566"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU6074524.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(32166..32906)
                     /locus_tag="VVR08_000567"
     CDS             complement(32166..32906)
                     /locus_tag="VVR08_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6074525.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(32906..35071)
                     /locus_tag="VVR08_000568"
     CDS             complement(32906..35071)
                     /locus_tag="VVR08_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6074526.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            35244..36197
                     /locus_tag="VVR08_000569"
     CDS             35244..36197
                     /locus_tag="VVR08_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6074527.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            36274..38262
                     /gene="uvrB"
                     /locus_tag="VVR08_000570"
     CDS             36274..38262
                     /gene="uvrB"
                     /locus_tag="VVR08_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU6074528.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            38272..38835
                     /locus_tag="VVR08_000571"
     CDS             38272..38835
                     /locus_tag="VVR08_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074529.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            38801..39289
                     /locus_tag="VVR08_000572"
     CDS             38801..39289
                     /locus_tag="VVR08_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074530.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            39363..39830
                     /locus_tag="VVR08_000573"
     CDS             39363..39830
                     /locus_tag="VVR08_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6074531.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(39827..40342)
                     /locus_tag="VVR08_000574"
     CDS             complement(39827..40342)
                     /locus_tag="VVR08_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU6074532.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(40354..40881)
                     /locus_tag="VVR08_000575"
     CDS             complement(40354..40881)
                     /locus_tag="VVR08_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6074533.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(41164..41727)
                     /locus_tag="VVR08_000576"
     CDS             complement(41164..41727)
                     /locus_tag="VVR08_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6074534.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(41711..42262)
                     /gene="coaC"
                     /locus_tag="VVR08_000577"
     CDS             complement(41711..42262)
                     /gene="coaC"
                     /locus_tag="VVR08_000577"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU6074535.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(42274..42963)
                     /gene="coaB"
                     /locus_tag="VVR08_000578"
     CDS             complement(42274..42963)
                     /gene="coaB"
                     /locus_tag="VVR08_000578"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU6074536.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            43193..44863
                     /locus_tag="VVR08_000579"
     CDS             43193..44863
                     /locus_tag="VVR08_000579"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU6074537.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSIGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            45191..46366
                     /gene="mutY"
                     /locus_tag="VVR08_000580"
     CDS             45191..46366
                     /gene="mutY"
                     /locus_tag="VVR08_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU6074538.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            46422..47126
                     /locus_tag="VVR08_000581"
     CDS             46422..47126
                     /locus_tag="VVR08_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074539.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            47119..48468
                     /gene="vicK"
                     /locus_tag="VVR08_000582"
     CDS             47119..48468
                     /gene="vicK"
                     /locus_tag="VVR08_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU6074540.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPVNSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            48470..49279
                     /locus_tag="VVR08_000583"
     CDS             48470..49279
                     /locus_tag="VVR08_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6074541.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            49370..49612
                     /locus_tag="VVR08_000584"
     CDS             49370..49612
                     /locus_tag="VVR08_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU6074542.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            49614..49868
                     /locus_tag="VVR08_000585"
     CDS             49614..49868
                     /locus_tag="VVR08_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU6074543.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            49915..50658
                     /locus_tag="VVR08_000586"
     CDS             49915..50658
                     /locus_tag="VVR08_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEU6074544.1"
                     /translation="MNKKWLFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLTKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLWTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGVLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(50947..51933)
                     /locus_tag="VVR08_000587"
     CDS             complement(50947..51933)
                     /locus_tag="VVR08_000587"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU6074545.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            52127..54595
                     /gene="gyrA"
                     /locus_tag="VVR08_000588"
     CDS             52127..54595
                     /gene="gyrA"
                     /locus_tag="VVR08_000588"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU6074546.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVIIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            54595..55338
                     /gene="srtA"
                     /locus_tag="VVR08_000589"
     CDS             54595..55338
                     /gene="srtA"
                     /locus_tag="VVR08_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU6074547.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT        17157 a         9659 c        12113 g        16457 t
ORIGIN      
        1 tagaaaaaag tctttaaaat tataaaacgc atcatatcaa ggtttttcaa aaaacttgat
       61 atgatgcgtt ttattgtggg aatatgtatt tcattttcta ctaaaattat gtttttgaat
      121 aacctctatc ttagtagtct gtataatccc cctcaatcag tttttgcgat aagctttaat
      181 gctatgacta taccactctt gcatttcttt tgatggtggt gtcatataat cgccatacat
      241 ctgggttaaa aattggtcat attttttggg aacaggcaac atacggccct caaactcagt
      301 taaaatcagt tctttaaagg tatcaactgg gaagatttct ttcatccctt ccttaccgat
      361 cccaactcct ccttcatatt gaggagtgtt ggttacagca tttttgacta gttgatcaat
      421 tttcttgtaa aagtagcgag gattgacaaa tcggagagcg taccagctac ataatctaag
      481 aaaatctttt agtttgctat caccgtgaac tgctcgtgat tttttgatat aagctagttg
      541 acgaagggcc acatacttat agctcttgtc gacaatgctc aagtctgtaa atcgatcaat
      601 tgggaagaca tcgatgaaaa ggctggtatc atgacgcttg tacttaacat ggtcttctat
      661 aacagtagaa gtgtccaaaa tcgatgcgaa attatggaag taccaagaag atgtatcgta
      721 ggaaagaact ttgtagcgat ggtgattttc ttcttcaata atcttcagta aacgctcata
      781 atcctcacga taaagggaaa tatcaatatc atcatcccaa ggaatcatac ctttgtggcg
      841 gatggctcca agcatggttc cataactgag aaaataagga atatcatgtt tcttacaagt
      901 ctcatcaata tagtccagca gggctagttg aatttcttta atttcttttt tttctaaata
      961 ttgcatccta atcctccaat ttataagcgt gaaattcatg actgtagaag cgtttttctt
     1021 ctggtggtag ggtcatataa tctccataaa attgtgtcaa aatagtatca aatttttcag
     1081 gtgcaggaag gcttaaattc tcaaagggta aatcgattgt tttatcaaag gtaccacttg
     1141 ggaagacttc cttttcctta aattttgaag gaataaaagc catatactgc ccattttcac
     1201 gactatattt ttgaatttct ttctcgattt tatttgcaaa ataacgagga gaaaccggtc
     1261 gaaggagcaa ccaaaaggct gttcgtatcc aatcttttaa aaggctatcc ttatagacaa
     1321 tatttttatg tttactgaaa gacagcagtt tgaagctttc cagtttataa caagtatcaa
     1381 tgaccttagg atcatcaaag cgatccatag ggaaaatatc gataaagata ccagactcat
     1441 aggtttttgt atttcgagta tcaataattt tagtcgtact gtcggttatc ttgataaagt
     1501 tgttaaagta gttcttatca gtttctaagg ataggagctt atacttgctt ttttcctttt
     1561 gaaaaatgtt aataaatcgt tggtagtctt ctctaggcat ggacagatca atatcgtcgt
     1621 cccaagggat aaagccctca tgtcgaaccg ccccaatcag agtaccgtag ttaataatat
     1681 agttgatatt gtgcttttta cagagagtat caatataatc caaaatttct aattcaattt
     1741 gtttggcatc ttcaacggtt agttgtttca ttttaaactc ctatgatttt ttgaatttat
     1801 tttttaaggc taggacatgg tttaaaaatt catagaaaat gctatctttt gtgaagacaa
     1861 gtagactaat ataagagata gctgataaca agacaatcaa accagtatta atcaaaaatg
     1921 gcaaattaat gaccatatcc acaggataca cgaaattaat caggaaataa attcccacaa
     1981 aggaaagtga aaagagcgag tatcgaacag tatagctaaa gatatgtccc aagtggatga
     2041 gttgttttct atggatgaaa atgatataga aaacaagtag agaagtctct gataacatag
     2101 ttgtcagtaa gtagtattca ggagccacga tatggttgaa aaagaggaga ctattcaagc
     2161 ccaaattgag tagcccagca aagactgtat agactgtgat acgtttttca tagccattgg
     2221 taaagagaat ttgggaacca agaatggtat ctaaggccag aataatcgta cgaaaagcga
     2281 agagagaggt caagatgccg cctccgatat atttttcact accgtaaagt aggatggcat
     2341 ttggtcctaa aaccatgagt ccaaaactca gtggaatgat aaagaagtta aagattcgac
     2401 tacctctatt aaccagagaa acataggctt ctttgtctcc tttccccaga tagtaactga
     2461 gacgaggcac actcactcca attgcacctg ttacaacccc agctataacg gtcacaattc
     2521 gctgagctat ggtatagtaa ctaacgttga catcaatccc tgttttaacg aggaagaggc
     2581 gatctaaaaa agtgaagagc atattggcat tggcaaagac taacatggct gtcagaggga
     2641 gaaagagtgg tttaaaatca cttaggtgaa tcttaacaag tttgatgtct cttttaatcc
     2701 aaaaataact aatcaggtag ttaatcagcg tcgataaact catcacaagt gtatagacaa
     2761 caatatcgtg ttcattttta acaaataaga aaatagagac cagcatcagg atacggatga
     2821 aggcagtttt gtaaaagaga aaactgtaat tttccagagc ttcattgacc cattcgattg
     2881 aaaaaatctg ggcaatgagt tgaatcccca taacaaggta gacctttttg acgattggat
     2941 tatcagtaaa gaagagagga taggctagga tatagacagc agtggtcaaa atcgtacaag
     3001 cgatgcacaa ataaaaaaga ctagaaaagg tcctgttaag atcttttttg ttatccttga
     3061 cattactgat agcccttaaa ccgtagttat agacaccata agttgcaaag ggcaagaaaa
     3121 atgacaaaat agtgtcgact gagttgaagt aaccatagtc agttcggtcc aagacacgcg
     3181 cgacataggt tccagttagg atgggaaaaa taatattcaa gacacgaatt cccatgtaag
     3241 atagagcatt taattttata cttttcattc aatttacctc gtttttcatt atatcataaa
     3301 gttagctaat aagaaatgaa gggcagtaag tcaagtaatc actttgaagt ttcaaatctt
     3361 aagttttaag ttttctttaa ggaaagtata ttattctgaa ggactctaaa atttcgcagc
     3421 catttattag taattgctac agaattccta gtcattccta gaaatggact agtttctttg
     3481 aataatagaa ctgcataatt ctcctattct agaaggggag gaccagtatt tcttttatga
     3541 taggactaga ttgtggtata atagagagaa taagtttttt tagtaagaca aaggagaaaa
     3601 tagatgattt atgcaggaat tcttgccggt ggaactggca cacgcatggg gatcagtaac
     3661 ttgccaaaac aatttttaga gctaggtgat cgacctattt tgattcatac aattgaaaaa
     3721 tttgtcttgg agccaagtat tgaaaaaatt gtagttggtg ttcatggaga ctgggtttct
     3781 catgcagaag atcttgtaga taaatatctt cctctttata aggaacgtat catcattaca
     3841 aagggtggtg ctgaccgcaa tacaagtatt aagaaaatca ttgaagccat tgatgcttat
     3901 cgtccgctta ctccagagga tatcgttgtt acccacgatt ctgttcgtcc atttattaca
     3961 cttcgcatga ttcaggacaa tatccaactt gcccaaaatc atgacgcagt ggacacagtg
     4021 gtagaagcgg ttgatactat cgttgaaagt accaatggtc aatttattac agatattcca
     4081 aatcgtgctc acctttatca aggacaaaca cctcaaacat tccgttgcaa ggacttcatg
     4141 gacctttatg gatctctttc tgatgaagag aaggaaatct tgacagatgc atgtaaaatc
     4201 tttgtgatca aaggaaaaga tgtggccttg gccaaaggtg aatactcaaa tctgaagatt
     4261 acaaccgtaa cagatttgaa gattgcaaaa agtatgattg agaaagacta gtaaaatgat
     4321 taatcaaatt tatcaactaa ctaagcctaa gtttatcaat gtcaaatatc aggaagaggc
     4381 tattgaccaa gagaatcata tccttatccg tcccaactac atggctgtct gtcatgcgga
     4441 tcagcgttac tatcagggaa aacgtgatcc caagattttg aataaaaagc ttccaatggc
     4501 aatgattcac gagtcatgtg gaaccgtcat ttctgacccg accggaacct acgaggttgg
     4561 tcaaaaagtt gtcatgattc ccaatcagtc tcctatgcag agtgatgaag aattctatga
     4621 aaactacatg acagggaccc atttcttgtc tagtggattt gatggcttta tgagagagtt
     4681 tgtttctctc cctaaagatc gtgtggtggc ttatgatgct attgaagata cggttgcagc
     4741 cattacagag tttgtcagtg tgggcatgca cgctatgaat cgtctattga ctcttgctca
     4801 tagcaagcgg gagcggatcg ccgttattgg agatggaagt ttagcttttg tggttgccaa
     4861 tattatcaac tatactttgc cagaatcaga gattgtggtt attggtcgtc attgggaaaa
     4921 gttggaactc ttctcatttg ccaaagaatg ctatattacg gataatattc ctgaagattt
     4981 ggcctttgac catgcttttg aatgttgtgg tggtgatggt actggaccag ctattaatga
     5041 cttgattcgc tacattcgtc ctcagggaac aattctcatg atgggagtta gcgaatataa
     5101 agtcaatctc aatactcgcg atgccttaga aaagggcttg attttggttg ggtcatctcg
     5161 ttctggtcgc attgattttg aaaatgctat ccaaatgatg gaagtcaaga aatttgccaa
     5221 tcgtcttaaa aatatccttt atctagaaga acctgtaaga gaaattaaag atattcatcg
     5281 tgtctttgca accgatttaa acacagcctt taaaacagtg tttaagtggg aagtataagt
     5341 actggaggtt aattgtggag aaaatcatta aagaaaaaat ttcttcctta cttagtcaag
     5401 aagaggaagt cctcagtgtt gaacaactgg gtggaatgac caatcaaaac tatttggcca
     5461 aaacaacaaa taagcaatac attgttaaat tctttggtaa agggacagaa aagcttatca
     5521 atcgacaaga tgaaaagtac aatcttgaac tactaaagga tttaggctta gatgtaaaaa
     5581 attatctttt tgatattgaa gctggtatca aagtaaatga gtatatcgaa tctgcgatta
     5641 cgcttgattc aacgtcaatc aagaccaagt tcgacaaaat tgctccaata ttacaaacta
     5701 ttcatacatc tgctaaggaa ttaagaggag aatttgctcc ttttgaagaa atcaaaaaat
     5761 acgaatcctt gattgaagaa caaattcctt atgccaacta tgaatctgtt agaaatgtag
     5821 tcttctcctt agagaaaaga ctggctgact taggtgttga cagaaaatct tgtcatatcg
     5881 atttggtgcc tgaaaacttt atcgaatcac ctcaaggacg actttatttg attgactggg
     5941 aatattcatc aatgaatgat ccaatgtggg atttggctgc cctcttttta gagtctgaat
     6001 tcacttccca agaggaagaa actttcttat ctcactatga gagtgaccaa acaccggttt
     6061 ctcatgaaaa gattgctatt tataaaattt tacaagatac tatttggagt ctatggactg
     6121 tatataagga agagcaaggt gaagattttg gtgactatgg tgtgaatcgt taccaaagag
     6181 ctattaaagg tttggcttct tatggaggtt cagatgaaaa gtaaaaacgg agttcctttt
     6241 ggccttctct caggtatttt ctggggcttg ggtctaacgg ttagtgctta tatcttttcg
     6301 atttttacag atttgtcacc ctttgtggtg gctgcagctc atgatttttt gagcatcttt
     6361 atcttactag cttttctctt ggtaaaagaa gggaaagttc gcctctcaat tttcttaaat
     6421 attcgcaatg tcagtgttat catcggagcc ttgctagcag gccctatcgg tatgcaggcc
     6481 aatctttatg cagttaagta tatcggaagt tctttagctt catctgtatc ggctatttac
     6541 cctgcgattt cagttctatt ggctttcttc tttttgaagc acaagatttc gaaaaatact
     6601 gtatttggaa ttgtcttgat tattggaggg attattgccc agacctataa agttgaacag
     6661 gttaattcct tctacattgg gattctctgt gctttggttt gtgctattgc atggggaagt
     6721 gagagtgttc ttagctcctt tgctatggaa agtgaactga gtgaaatcga agccctctta
     6781 atccgtcaag tgacttcgtt cttgtcctat cttgtgattg tgctcttctc tcatcagtca
     6841 tttactgcag tagccaatgg acaattgcta ggtctcatga ttgtttttgc agcctttgat
     6901 atgatttcct acttggctta ttatatcgct atcaatcgct tgcaaccagc caaggctaca
     6961 ggcttgaacg tgagctatgt agtatggacg gtcttgtttg cagttgtttt cttgggtgca
     7021 ccgctagata tgctgacaat tatgacgtca cttgtcgtca ttgctggagt ttatattatt
     7081 attaaagaat aaaggagatt cgtgtgaaag ccatcatctt agcagcggga ttgggaactc
     7141 gcttgcgtcc tatgactgaa aataccccta aagccttggt tcaggttaat caaaaacctt
     7201 tgattgagta ccaaattgag tttctcaaag aaaaaggaat caatgacatc atcatcattg
     7261 ttggttatct taaagaacaa ttcgattact tgaaagagaa atacggtgtt cgtctcgttt
     7321 tcaatgataa atacgctgac tacaataact tttactctct ctatcttgta aaagaagaat
     7381 tggccaacag ctatgttatt gatgctgaca attatctctt taaaaatatg ttccgcaatg
     7441 atttgacacg ttcgacttat tttagtgttt atcgtgaaga ttgtaccaac gaatggttct
     7501 tggtctatgg agatgactac aaggttcaag acattattgt tgatagcaag gcaggtcgca
     7561 tccttagtgg tgtatccttc tgggatgctc caactgcaga aaagattgtc agctttatcg
     7621 acaaggctta tgcaagtggt gaatttgttg atctctactg ggacaatatg gttaaggata
     7681 atatcaaaga gctagatgtc tatgttgaag aattagaagg caatagcatt tatgagatcg
     7741 atagtgtcca agactatcgt aaattagaag aaattcttaa aaacgaaaat taaagattcc
     7801 aacatctgac aaaatagtcg gatgtttttt gattttttac gaatagatag atgagtagaa
     7861 aaagaaatgg agttatttat gaaaatcaca aactatgaaa tctataagtt aaaaaaatca
     7921 ggtttgacca atcaacagat tttgaaagtg ctagaatacg gtgaaaatgt tgatcaggag
     7981 cttttgttgg gtgatattgc agatatctca ggttgccgta atccagccgt ttttatggaa
     8041 cgttattttc agatagacga tgcgcatttg tcgaaagagt ttcaaaaatt tccatctttc
     8101 tctattttag atgactgtta tccttgggat ttgagtgaaa tatatgatgc gcctgtactt
     8161 ttattttaca agggaaatct tgacctcctg aaattcccga aggtagcggt cgtgggcagt
     8221 cgtgcttgta gcaaacaggg agctaaatca gttgaaaaag tcattcaagg cttggaaaat
     8281 gaactggtta ttgtcagtgg tctggccaag ggcattgaca cagcagctca tatggcagct
     8341 cttcagaatg gcggaaaaac cattgcagtg attggaacag gactggatgt gttttatcct
     8401 aaagccaata aacgcttgca agactacatc ggcaatgacc atctggttct aagtgaatat
     8461 ggacctggcg aacaacctct gaaatttcat tttcctgccc gtaatcgcat cattgctgga
     8521 ctttgtcgtg gtgtgattgt agcagaggct aagatgcgtt caggtagtct cattacgtgt
     8581 gagcgagcaa tggaagaagg acgcgatgtc tttgctattc ctggtagcat tttagatgga
     8641 ctatcagacg gttgccatca tttgattcaa gaaggagcaa aattgctcac cagtgggcaa
     8701 gatgttcttg cggaatttga attttaaaaa tgacctaagc tagaattcta agaaaaaatc
     8761 aattttaaga gaaaatgaac ccaacatttc cataataaaa cgcatattag caagttttta
     8821 acacttgcta atatgcgttt tttctaagtg gattagtaga gtagaggatt tttctcatat
     8881 aatactcttc gaaaatctct tcaaactacg tcagcttcca tctgcaacct caaaacagta
     8941 ttttgagctg agttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgt
     9001 ggctagcttc ctagtttgcg ctttgatttt cgttgagtat aagggaaagt atagtgaatt
     9061 gaaataagat gtgaacaact ctaccaggaa agtcaaatta atttatagaa atattttagc
     9121 agccaaggtg cactgttata gattcaatac actataattt agtgtaattg agaaaggaga
     9181 aatgattgtg attgatgttg gctaggttat gttcaatgat tcctaccatc tcaaatcttg
     9241 ttagtaagga aaaataaatt cttcaaaagt agagattaca aggcttgttt aagaaagaat
     9301 tcaaagacct tgacaaataa aaataaaatg gttattataa aaaatggtct gaaatagatg
     9361 atgatacttt tcgaaaatct ttttacgtca gctcagcttt gccttgctgt gttttgagca
     9421 agctacggtt agcttccgag tttgattttc atttactaga aatgaaactg atgagagata
     9481 tcagtagaca tttgagtcag gatattatgg aaaatgataa aaagagctcg tgagattggc
     9541 atatcagact actaaagtat tgagtttgtt aggattttag cgactagtta gctgggaaag
     9601 gaagatattt gtgacaaata ataaactgta ttcgttgata gaatttagaa ataaaatata
     9661 tgaagaatta gaactttcca gaagtgattt agcgatttta ctatgtgcca tgcttatcgc
     9721 ctctatcgga ttaaatatgg attcgactcc cgtgattatt ggagccatgt taatctctcc
     9781 tttgatgaca cctattctgg gagtggggct ctctctagct atatttgatt ttaaattgtt
     9841 aagaaaatct tttaaaatat tagctattca aattcttgcc agtttaatag cttcaacact
     9901 ttatttttat ctttctccca tttcgtatgc tagttcggaa attgttgcta gaacctctcc
     9961 gactatttgg gatgttctca ttgcttttgt aggagggata gcaggtatta ttggtgctag
    10021 gaaaaaagag accaataata ttgttcctgg tgttgctatt gcaaccgcct tgatgcctcc
    10081 tctttgtaca gtaggttatg ctattgcttc tgctaatcta aaatttatca taggctcctc
    10141 ttacctattc ctcatcaatt gtagctttat tgtcattgcg acttatatag gtgttaggtt
    10201 gatgatggtt aagaaacatt attttaaaga taatgaagaa gactctaaaa tgcgtaggat
    10261 tttgcttcta gttgctgttt tgctgatgat tccgagtttc atctctgcaa cgactttagt
    10321 gagagaaacg ttgaaaaaag agtcccttaa gaaatttata tcagagcagt ttcaggggta
    10381 taatattttg aaaaaaacct attctaaaaa gactcatacc ctaaagctaa ccatttcagg
    10441 aaattatttg acagaagaag aactcgatat gatttcaagt aagagaggtg actatggttt
    10501 aagtgatgtt tctgttcaag tttcacaatt gtctgattca gaacaactta gtaaggaaga
    10561 gctggtggag catttcttcc agtatatcaa ggataaggaa gcaaaagaaa aggagaaagc
    10621 caataaattt gatacagagt ctgaggagca ataatttctt gagaatagct ggtttctctc
    10681 gtgagtcttc tatgtatatc aaaggaagac tgaggtttta agtataaaac ttttcttcta
    10741 ttatagtagc taagtcttga cagggttcaa aaaatggttt acactttata aagtttatta
    10801 ctttgaaaag gtgtgatact gtggctacgg caacaaaaaa gaaaaaatca acagttaaaa
    10861 aaaatctagt catcgtggag tcgcctgcta aggccaagac gattgaaaaa tatctaggca
    10921 gaaactacaa ggttttagcc agtgtcgggc atatccgtga tttgaagaaa tccagtatgt
    10981 ccgtcgatat tgaaaataat tatgaaccgc aatatattaa tatccgagga aaaggccctc
    11041 ttatcaatga cttgaaaaaa gaagctaaaa aagctaataa agtttttctc gcgagtgacc
    11101 cggaccgtga aggagaagcg atttcttggc atttggccca tattctcaac ttggatgaaa
    11161 atgatgccaa ccgtgtggtc ttcaatgaaa tcaccaagga tgcagtcaaa aatgctttta
    11221 aagaacctcg taagatcgat atggacttgg tcgatgccca acaagctcgt cggatcttgg
    11281 atcgcttggt agggtattcg atttcgccta ttttgtggaa gaaggtcaag aagggcttgt
    11341 cagcaggtcg cgttcagtcc attgccctta aactcatcat tgaccgtgaa aatgaaatca
    11401 atgccttcca gccagaagaa tactggacag ttgatgctgt ctttaaaaag ggaaccaaac
    11461 aatttcatgc ttccttctat ggagtagatg gtaaaaagat gaaactgacc agcaatgacg
    11521 aagtcaagga agtcttgtct cgtctgacta gtaaagactt ttcagtagat caggtggata
    11581 agaaagagcg caagcgcaat gctcctttac cctataccac ttcatctatg cagatggatg
    11641 ctgccaataa aatcaatttc cgtactcgaa aaaccatgat ggttgcccaa cagctctatg
    11701 aaggaattaa tatcggttct ggtgttcaag gtttgattac ctatatgcgt accgattcga
    11761 ctcgtatcag tcctgtagcg caaaatgagg cggcaagctt cattacggat cgttttggta
    11821 gtaagtattc taagcacggt agcaaggtca aaaacgcatc aggtgctcag gatgcccatg
    11881 aggctattcg tccgtcaagt gtctttaata caccagaaag catcgctaag tatctggaca
    11941 aggatcagct caagctatat acccttatct ggaatcgttt tgtggctagc cagatgacag
    12001 cggccgtttt tgataccatg gctgttaaat tgtctcaaaa aggggttcaa tttgctgcca
    12061 atggtagtca ggttaagttt gatggttatc ttgccattta taatgattct gacaagaata
    12121 agatgttacc ggacatggtt gttggagatg tggtcaaaca ggtcaatagc aaaccagagc
    12181 aacatttcac ccaaccgcct gcccgttatt ctgaagcaac actgattaaa accttagagg
    12241 aaaatggggt tggacgtcca tcaacctacg cgccaaccat tgaaaccatt cagaaacgtt
    12301 attatgttcg cctggcagcc aaacgttttg aaccgacaga gttgggagaa attgtcaata
    12361 agctcatcgt tgaatatttc ccagatatcg taaacgtgac cttcacagct gaaatggaag
    12421 gtaaactgga tgatgtcgaa gttggaaaag agcagtggcg acgggtcatt gatgcctttt
    12481 acaaaccatt ctctaaagaa gttgccaagg ctgaagaaga aatggaaaaa atccagatta
    12541 aggatgaacc agctggattt gactgtgaag tgtgtggcag tccaatggtc attaaacttg
    12601 gtcgttttgg taaattctac gcttgtagca atttcccaga ttgccgtcat acccaagcaa
    12661 tcgtgaaaga gattggtgtt gagtgtccaa gctgtcatca gggacaaatt attgagcgaa
    12721 aaaccaagcg taatcgccta ttctatggtt gcaatcgcta tccagaatgt gaatttacct
    12781 cttgggacaa gcctgttggt cgtgactgtc caaaatgtgg caacttcctc atggagaaaa
    12841 aagtccgtgg tggtggcaag caggttgttt gtagcaaagg cgactacgag gaagaaaaga
    12901 ttaaataaga ggaggggccc gaaagtaaat ttcaggctcc ttttggttag aacttgacaa
    12961 aatacatcat tttatgcgaa actagaagaa gattatttta tactcaatga gaatcaaaga
    13021 gcaaattaga aagctagtcg caggttgctc aaagcactac tttgaggttg aagatggaag
    13081 ctgacctggt ttgaagagat tttcgaagag tattaactag gagaagttat gcgtcttatc
    13141 tatctgataa ttggtttttt atcactggcc ttggctattg ttggggttgt tttacccttg
    13201 ttgccgacaa cgcctttcct tttgttgtct attgcttgtt tctccagaag ttccaagcgt
    13261 ttcgaagact ggctttatca taccaagctc tatcaaacat atgtagctga ttttcgcgag
    13321 actaagtcta ttacgcgtga acgaaagaaa aaaatcatcg tctctatcta cgtcttgatg
    13381 ggaatttcta tttattttgc acctctttta ccagtcaaaa tcggtctggg tgctttgacc
    13441 atctttatca cttattatct tttcaaggtc attccagaca aagaatagtt aaaacagtag
    13501 ttatttgcct tgataaaatt gaaagcatat tcataataat atgatataat aaatttgaag
    13561 taatattcaa ggagaatcaa atgatttacg aattttgtgc tgaaaatgtg actttacttg
    13621 aaaaagcgat gcaggctgga gctcgtcgga ttgaactctg tgataatcta gcagtcggtg
    13681 ggacaacacc cagctatgga gtgactaagg cagcggttga actggcagct aactacgata
    13741 caaccatcat gaccatgatt cggccacgtg gtggtgactt tgtctataat gacctagaaa
    13801 ttgctatcat gctagaagac attcgtttga ctgctcaggc tggaagtcaa ggggttgtat
    13861 ttggagcttt aactgctgat aaaaagttgg ataagcctaa tctggaaaag ttaattgctg
    13921 catcaaaagg aatggaaatt gtctttcaca tggcctttga tgaactaagt gatgaagatc
    13981 aaccggaagc tattgactgg ctcagtcaag ccggtgtcac tcgtatccta actcgtgctg
    14041 gtgtgtctgg cgactcctta gaaaaacgtt ttgttcacta tcacagaatt ttggagtacg
    14101 ctaaaggtaa aattgaaatt ctaccaggtg gggggattga ccttgaaaac cgtcaaacct
    14161 ttatcgacca ggtgggggta acacaattgc atggtactaa ggttgttttt taaaaaatag
    14221 aaaggaactg ctagcttttg gtagcagttt tcacttatgt ttgaaatttt taaatcctat
    14281 caatttaatc aagaaaaggc tcatgattat ggttttatag aaaatagcga agtctggaca
    14341 tatagttgcc agattttgca aggtgacttt gtcatgactg tgtccatcac tgctgataat
    14401 gtgaactttc aagtctttga ccaagagact ggtgacctct atcctcatgt tcatatggaa
    14461 agcatgaggg gaagttttgt cggaaatgtc cgtgaggctt gtctggagat tctttaccag
    14521 attcggaagg cttgttttga tgtgcaagat tttatctgtc atcagactaa gcgtatcatg
    14581 actcaagttc aggaaaagta tggaaaccag ttggagtatc tgtgggaaaa atcgcctgat
    14641 acagctgtat tgcgccatga aggcaatcaa aagtggtatg ccgtcttgat gaaaatctct
    14701 tggaataagc tggaaaaggg cagagaagga caagtggaag cagtcaacct caagcatgac
    14761 caagtagcta atttgctttc acaaaagggg atttatccag ccttccatat gagcaagcgc
    14821 tactggatta gtgtgtccct tgatgatact ttatcagatg aagaagtact ggaattgata
    14881 gaaaaaagtt ggaacttaac ctctaaaaaa tgaaatattt taataatttt catgaacttt
    14941 caattagcta aatattcttt actgaagaga tttttagaaa atataggatt taccacacta
    15001 gaggaatatg gtgccatctt caaatacctg attgagaatg tcaagacgga tcgtcagatc
    15061 atctattcgc ctcactgtca tgatgacctc ggaatggcag tggcaaatag ccttgctgct
    15121 gtcaagaatg gtgcaggacg tgttgaaggg actatcaatg gtattaggga gcgagctgaa
    15181 aatgctgctt tggaagaaat tgcagtggct ctcaatattc gccaagatta ctaccaagta
    15241 gaaaccagta ttgtcctaaa tgagaccatc aatacgtcag aaatggtttc tcgcttctct
    15301 ggtattccag ttcctaaaaa caaagccgtc gttggtggca ataccttctc ccacgaatct
    15361 ggtattcacc aagatggagt ccttaaaaat cctctcactt atgagatcat cacacctgaa
    15421 ttggttggtg ttaagattcc gcttggaaaa ttatctggtc gccatgcttt tgttgagaaa
    15481 ctgagagaat tggccctaga ttttacagaa gaggatatca aaccactctt tgctaagttc
    15541 aaggcactgg ccgataagaa gcaagaaatc acagatgcag atattcgagc tttggtagct
    15601 ggaaccatgg ttgaaaatcc agaaggcttc cactttgatg atttacaact tcaaactcat
    15661 gcagataatg acattgaagc gctcgttagc ctagccaata tggatggtga gaaagtcgaa
    15721 tttaatgcga cagggcaagg ttccgttgaa gcaatcttta acgctatcga taagttcttt
    15781 aatcaatctg ttcgtttggt gtcctacact atcgatgcag taacagatgg aatcgatgcc
    15841 caggatcggg ttttggtcac tgttgaaaac agagatacag aaaccatctt taatgcagca
    15901 gggcttgatt ttgatgtgtt gaaggcttct gctattgcct atataaacgc taataccttt
    15961 gttcaaaaag agaatgcagg tgagatggga tgcagtgttt cttaccatga tatgcctagt
    16021 gtgtaaagga gaaggctatg gcaaagaaaa tagtagctct agcaggagac ggaattggcc
    16081 cagaaatcat ggaggctggt ttagaagttc tggaggctct agctgaaaaa acaggttttg
    16141 actatgagat tgacagacga ccgttcggag gtgcagatat tgatgcagca gggcctccct
    16201 tacctgatga aacccttaag gcaagtaggg aagcagatgc tatcctacta gcagctatcg
    16261 gtagtcctca gtatgatgga gcagtggttc gccctgaaca aggcctgatg gctctccgta
    16321 aggaactcaa tctttacgct aatattcgtc ctgtaaaaat ctttgacagt ctcaagcatt
    16381 tgtcaccact caaactggaa cgaattgctg gtgtagactt tgtcgtggtg cgtgaattga
    16441 caggcgggat ttactttgga gatcatattc ttgaagagcg caatgcgcgt gatatcaacg
    16501 actatagcta tgaggaagtg gagcggatta ttcgcaaagc ctttgaaatt gcaagaaatc
    16561 gcagaaaaat cgttactagt atcgataagc aaaatgttct agcgacctca aaactctggc
    16621 ggaaagtagc tgaggaagtc gcacaggatt tcccagatgt aaccttggaa catcagctgg
    16681 tagactcagc tgctatgctt atgattacca atcctgctaa gtttgatgtt attgtaacgg
    16741 agaatctttt tggagatatt ttatctgatg aatcaagcgt cttatctggt acacttgggg
    16801 ttatgccatc agccagtcat tctgaaaatg gaccaagtct ctatgaacct attcacggtt
    16861 cagcacctga tattgcaggt caaggaattg ccaatcctac ttccatgatt ttatcagttg
    16921 ccatgatgtt gagagatagt ttcggacgtt atgaggatgc agagcgtatc aaacgtgctg
    16981 ttgagacaag tctggcggca ggaattttaa cgagagatat aggaggtcag gcttcaacaa
    17041 aggaaatgac ggaagctatt attgcaaggt tatgaagtta gacgaaaaaa ttactctagt
    17101 ccttttgatt tggaatgtca tcattttctt gatttatggc attgacaaat tcaaggcaag
    17161 aagaagagct tggcgcatcc cagagaaaat cttactcatt ttagccctta cttgtggtgg
    17221 ttttggggcc tggttagctg gaattacttt tcaccacaag actcgaaaat ggtactttaa
    17281 aacagtttgg tttcttggga tggtgaccac actagtagcc ttatatttta tttggaggta
    17341 atggatggca gggtcttcga gggaacacgc tgcttgggct ctagcggact atggttttaa
    17401 ggtcgtgatt gcaggatctt tcggtgacat tcattacaat aatgaactca ataatggcct
    17461 gttgccaatc gttcagccta gagaggttag agagaaatta gcccagctaa aaccaaccga
    17521 ccaggtaact gtggacttgg aacaacaaaa aatcatctca ctagttgaag aattcacctt
    17581 cgagatagat agcgagtgga aacataaact cctaaatagt ttggatgata tcggtattac
    17641 cttgcagtat gaagagttga ttgctgctta tgaaaaacaa cgaccagcct actggcagga
    17701 ttagaaaaaa tagaaaagga aatatagtaa actgaaataa gatgtaaaca aatgaattgg
    17761 agcttaacat ccatttccag caatttttta gaaactacag tggactattc tggattcaac
    17821 acattataaa attatgacaa aacacattca caagaaggct acgacatttt aaaaggtgag
    17881 ggcggatgta tcgtttgccc tactaaagtt ggttacatta tcatgaccag caacaaggca
    17941 gaacttgagc gtaagttcgc agccaaagaa cgtaagcgta acaaaccagg tgttgttctc
    18001 tgcggtatca tggatgaact tcgcgcttta gcgcaactca acccagaaat tgaagcattc
    18061 tactaaaaac attgggatga agatattctt cttggttgta tccttccttg gaaaccagaa
    18121 gcctctgaaa aactcaaagc atacggggat ggccgtgaag aacttatgac tgatgtacgt
    18181 ggtactagct gttttgttat caagtttgga aaagcaggtg aacaattggc tgccaagctt
    18241 tgggaagaag gtaaaatggt ctacgcctca tctgcttcaa tgacaaaacg attgaaactc
    18301 gctatgagag caaggtgtaa tggtgtctat ggtcgataag gatggcaaac tcatcccaga
    18361 acaaggagga gcacgttcaa cctcaccagc accagttgtg atccgtaaag ggcttgacat
    18421 tgataaaatc atgatgcacc tgtcagatac ttttaactca tgggactacc gtcaggttga
    18481 gtattattag gatagagaag aagtctagtg ttaaggacat tacagctcat aatactaggc
    18541 ttttttatag aaattctttt ctttttctat aggatatggt attctatgta gaaaatatat
    18601 gttaataagt aatgccaata tttaaacatc attagtaaaa ggagttagat tgatgaataa
    18661 aagaaaagtt agtttagaag atttttataa atggtatagt ctaaataaag aagagttatt
    18721 aaataaggca actgttggtg aaaagtttaa tgataaatta aaagaagagt ttctccagga
    18781 atggcctttg gataggattt taacaatgtc aatcgatgaa tatgtaatag gaaagggaca
    18841 gcaaaataag tctttatgct acgctcttga gaagggaaaa tacaaaaatc tatttcttgg
    18901 aatttctggt ggctcagctt caaaatttgg tatttattgg aataaaaaaa caaacaaata
    18961 taaagatcaa gctaataatg agatttcaga gttggatcag cgattttcaa aattaaaatc
    19021 agatttgtat gaaattatca aagaaggtat tcgttttaac tttgaaaatc ctatttttga
    19081 tatgaaaaga tcaacaaatg aatttattgg tcgttctgct atggtgacaa aattactttg
    19141 tatctattct gagggagatc ctttctttgg tgtaaatatt aatagtcaga aagaattttg
    19201 gaaccacttt gtttctcaga caaatcaagg tggaccttat ctgcaaaatc ataaaataat
    19261 tgaactggtg tccaaaactt atcctgagtt ggagctatcg aaattaggaa ctatgctttt
    19321 tgagtattct aagcttttta tggaaaataa ggaagacaat agtacaatgg attcatcaaa
    19381 caattttcgt catcaattaa ctcaatctct attaaagtct ccaaacctta tccttcgtgg
    19441 tgctcctggc acaggaaaga cttatcttgc taaagaaatt gccaaagaat taacggatgg
    19501 taacgaagac caaatcggat ttgtacaatt tcacccatcc tatgattata cggattttgt
    19561 agaaggttta agaccagtat caaatgggga tggagctatt gagtttaggc tacaggacgg
    19621 tatttttaaa gatttttgtc agaaagcaaa agaaacccaa ttgattggag gacaagataa
    19681 ttttgatgag gcttgggatt cttacttaga atatataaat gttgctgaag aaaaagaata
    19741 tataacaaaa acatcatact tatctgttaa tagtagacaa aatttgtcag taaattatga
    19801 tagtggtgtt ccaggatggt cactacctag caaatatgtt tacgagttgt ataaagataa
    19861 aaattataat aagcaagaat actacaaaag tggtggaaaa actgtcctag aaacattgag
    19921 aaagagattt ggtttgaaag actatgtttc cccaacagaa attgatactg ataagaaatt
    19981 cgtcttcatc atcgatgaaa tcaatcgtgg ggagatttct aagatttttg gcgaactctt
    20041 tttctctatc gaccctggct atcgtggtga aaaaggaagt gtttctaccc aatatgcaaa
    20101 tctacacgaa actgatgaaa agttctatat ccccgaaaat gtttacatca tcggaactat
    20161 gaatgatatt gatcgttcag tggatacctt tgattttgct atgcgtcgtc gttttcgttt
    20221 tgttgaagtt actgccgagg gtcaagttgg catgttggat aaagagctga atatccatgc
    20281 agaagaagca aaaattcgtc taagaaactt gaacgctgct atcgaaaatg ttcaggaatt
    20341 aaacagtcat tatcatattg gaccaagtta ttttcttaag ttgaaggatg tagattttga
    20401 ctatgaatta ctctggtctg attatattaa gcctctccta gaagactact tgcgaggttc
    20461 ttatgatgag gttgaaactt tggaaacttt gaaaaaagca tttgaactga caaataatga
    20521 gcaaaaagat caggcagtag ctgatgacaa tgaaggtgat gaaaacgatg atgcggatta
    20581 ctgataatca acacaagatt attaaagaaa aatttgttga agaatatcct aaactaagca
    20641 atcttctttt agacagaacc ttggaaagtc tatcccaaga tgaacgtatt ttcatttttc
    20701 caaatgattt gactcatact cctgatttgg ataaggatca aaagattttt gaaacagtca
    20761 atcagaaaat caagacaggg aacgtgattg gttttcttgg atatggtcag gaaagattaa
    20821 cgatttcctc acgattttct gatgagagta atgaccattt tttgcattat ctcttaaaca
    20881 aggttcttta tatcaatctc actagtttag atgttgcttt gtctcgtgaa gagaggcttt
    20941 atcaactttt gatgtatctc ttccccaagt atctacaagc tgctattcga aaaggtcttt
    21001 ataaggaata tcatcgattt tctcataacg acagtaatgt taagggagtg attgttgtaa
    21061 gaaaccatct caagaaaaat cttcctttca cgggaaatat tgcctacaca acgagagagt
    21121 tcacctatga taatcccctc atgcagttgg tccgtcacac tattgaatac attaagaatc
    21181 agaaaagcat tggtcaaggg gtactagata atctctcaac tagtcgtgaa aacgtatctg
    21241 aaatcgtgcg tgtaacgccc tcttataaac tagctgatcg tgctaagatt actcggagaa
    21301 atcaatctaa acctatacgt catgcatact ttcacgagta cagaaactta caagaacttt
    21361 gtctgatgat cctaaaccaa gaaaagcacg gtttagggta tcaagatcaa aaaatctatg
    21421 gtattctctt tgatgttgcc tggctttggg aagagtatgt ttacaccttg ttgccaaaag
    21481 gttttgtaca tcccagaaat aaggataaga cggatggaat ttcagtattt tctgttggga
    21541 aacgaaaagt atatccagat ttttatgaca gagaacgaaa gattgttcta gatgcaaaat
    21601 ataaaaaact ggaattgact gaaaaaggaa tcaaccgtga ggacttattc cagctgattt
    21661 cctattctta tattttaaaa gctgagaagg ctggacttgt ttttccgagc aaggacaagg
    21721 tcattgataa tgagatagga aacctagcag gttatggagc tttgttgaag aaatggtcta
    21781 tccaaattcc tcagaagtct tcatcttata gtgcattttg taaaatgatg gaaaattcag
    21841 aagaaaattt taaagcgatt attgatgaag aagtggggag aaaataattt cccctctttc
    21901 ttttattttt aacacaagca aaatccgaac aatatatttt aattcataaa ataatttgac
    21961 aaaaactgta ctttggttta taataaatta aggaaacgtc ggaaaaggcg tagtgatgcg
    22021 agagcatagg taggtcatta caaaagaaac gagacatcga tatgttaaat gaatttccaa
    22081 tttttgatta cgaagatatt caattgattc caaataaatg tgtcattaaa agccgtgcag
    22141 aagcggatac aagtgtcact ttaggaaatc acacctttaa actacctgtt gtgccagcga
    22201 atatgcagac gattttggat gaaaatgtag cagagcaact ggctaaaggt ggttacttct
    22261 acattatgca ccgttttgat gaggcaggac gcattccttt tattaaacga atgcacgatc
    22321 aagggctcat tgcttccata tctgtcggtg ttaaggatta tgagtatgat tttgttagcc
    22381 agctcaaggc tgatgctcct gagtatatca ctattgatat tgctcatggt catgcggata
    22441 gcgtgatttc tatgattcaa cacatcaaga aagaattgcc agataccttt gtcattgctg
    22501 gaaatgtggg aacaccagaa gctgtgcgtg aattggaaaa tgctggtgca gatgctacta
    22561 aggtcggaat cggtcctggt aaggtttgta tcaccaaggt taagactggt tttggtacag
    22621 gtggttggca gttggctgct ctacgctggt gtgccaaggc tgcgcgtaaa ccgattatcg
    22681 ctgatggagg aattcgtact cacggtgata ttgccaagtc tatccgcttc ggtgctagca
    22741 tgatcatgat tggttccctc tttgcaggac acattgaaag tccagggaaa acgattgaag
    22801 tcgatggtga acagttcaaa gaatattatg gttcagcctc acaatatcag aaaggtgctt
    22861 acaaaaatgt ggaaggcaaa cgtatcttgc ttcctgctaa aggtcatctg caagacactt
    22921 taactgagat ggaacaagac cttcaaagtg ctatttctta tgcaggtgga cgtcaggttg
    22981 ctgaccttaa acacgttgat tatgtgatcg tgaaaaactc catctggaat ggggatgctt
    23041 cccactaaga cggggtcttt gaccaaaaaa cttgttatta gagcaaattt ctgttataat
    23101 aaaacaagtt tccaccctta gtgtaatgga tatcacgtaa gattccggtt cttgagatgg
    23161 gggttcgatt ccctcagggt ggatgtaaac atcctaaaaa gcctttaata gggctttttt
    23221 ctttatcctg acccaaattt gccgctaaaa ctgagaatct ctgtctaaag aattcccaaa
    23281 tgctttccag tcccgtttta gagtgactca gggggctttt tttgatataa taaaaaggac
    23341 tattatcagt tagaaagaag ttggtatgaa agaattacaa actgtactaa agaatcattt
    23401 tgaaatcgaa tttgcagaca aaaagttact ggaaactgcc tttactcata cgagttatgc
    23461 caatgagcac cgcctcttaa aaatttcaca caatgaacgc ttggaatttt taggagacgc
    23521 tgttctacag ttattgattt cagaatatct atataaaaaa tatcctaaaa agcctgaagg
    23581 tgacctatca aaactccgtg ctatgattgt ccgtgaggag agtttagctg gttttgcgcg
    23641 tgattgccag tttgaccagt ttatcaagtt gggtaaaggg gaagaaaaat ctggtggtcg
    23701 caatcgtgac accattcttg gtgatgcctt tgaagccttt cttggtgccc ttcttttgga
    23761 taaggatgtg gcaaaggtca aggaatttat ctaccaagtt atgattccta aggtagaagc
    23821 aggcgaattt gagatgatta cagactataa aacccatctc caagagttgc ttcaggtcaa
    23881 tggtgatgtg gctattcgtt atcaagtgat ttctgaaaca gggcctgctc acgataaggt
    23941 ctttgatgta gaagttcttg ttgaaggtaa gagcatcggt caaggccaag gtcgttctaa
    24001 gaaattagca gagcaggaag ctgccaaaaa tgccgttgag aaagggctgg attcatgtat
    24061 ttaaaggaaa tcgaaattca ggggttcaag tcttttgctg ataagaccaa ggtcgttttt
    24121 gaccaaggtg tgacggcagt tgttggaccc aatggatctg gaaagtccaa tattacagaa
    24181 agtctgcgtt gggctttggg ggagtctagt gtcaagagtc tccgtggggg caagatgccg
    24241 gatgtcatct ttgctggaac agaaagtcgc aaaccgctca attatgcttc tgtagttgtg
    24301 actctggata atcatgacgg atttatcaag gatgcaggtc aagaaatcag ggtggaacgc
    24361 catatctatc gtagtggaga tagcgaatac aagattgacg gcaagaaagt ccgtctgcgt
    24421 gatattcatg acctcttctt ggatactgga ttgggacgag attccttctc tattatttcc
    24481 caagggaagg ttgaggagat ttttaattcc aagcctgagg aacgacgagc tatttttgaa
    24541 gaagctgctg gagttttaaa atacaagact cgcagaaaag aaaccgagag taaactgcag
    24601 caaactcagg ataatctgga ccgcttagag gacattatct acgagttgga taatcaaatc
    24661 aagcctcttg agaagcaagc tgagaatgcc cgtaagtttt tagacttgga aggacaacgt
    24721 aaggctattt atttagacgt tctggttgct caaatcaagg aaaataaggc agaactagag
    24781 tcgacagaag aagagttggc tcaggttcaa gaactcttga tgagttatta ccaaaagcgt
    24841 gaaaaattag aagaagaaaa tcaaactctt aaaaagcaac gccaagattt acaggctgaa
    24901 atggccaaag accaaggcag tttgatggac ttgactagtc tgattagtga tttagaaaga
    24961 aaattagccc tatcgaaact ggagtccgag caagtggccc tgaatcaaca ggaggcacaa
    25021 gctcgtttgg ctgctttgga ggataagaga aattcactca gcaaagaaaa gtatgataaa
    25081 gaaagctctt tagctctgtt agagggaaat ctagtccaaa ataatcaaaa actcaatcgt
    25141 ttagaagctg aattgctggc tttctcagac gatcctgatc agatgattga gctcttacgt
    25201 gaacgctttg tagctctttt acaagaagaa gcggatgtct caaaccagtt gacccgtatt
    25261 gagaatgagt tggaaaatag tcgtcagctt tctcaaaaac aagcagatca actagaaaag
    25321 ctgaaagagc aattagctac agctaaagag aaggctagtc agcaaaaaga cgagcttgaa
    25381 actgccaagg tgcaggttca gaaattattg gctgactatc aagctattgc caaggagcaa
    25441 gaggagcaga aaacttccta tcaagctcaa caaagtcaac tctttgaccg tctggatagt
    25501 ctcaaaaaca agcaggccag agctcaaagt ttggaaaata tcctgagaaa tcatagtaac
    25561 ttttatgcag gtgttaagag tgttctccaa gaaaaagatc gcctaggtgg gattattggt
    25621 gcagtcagtg agcatctgac ctttgatgtt tattatcaaa ctgccctaga gattgcctta
    25681 ggggcaagta gccagcatat catcgtagaa gatgaagagt cggcaaccaa agctattgat
    25741 ttcctcaaac gaaacagagt cggtcgtgca acctttcttc ctttgaccac tattaaggcg
    25801 cgtacgattt ctagtcagaa ccaagatgct atcgctgtaa gcccaggttt ccttgggatg
    25861 gcagatgagt tggtgacttt tgatactaga ctggaagcca ttttcaagaa cttgctagct
    25921 acgacggcta tctttgatac cgtagaacat gcgcgtgaag ctgctcgaca agttcgttat
    25981 caggttcgta tggtgacatt ggatgggaca gaattacgca cgggtggttc ctatgcgggt
    26041 ggtgccaatc gccaaaataa cagtattttc atcaagccag aactggagca attacaaaaa
    26101 gaaattgctg cagatgaagc aagcttgggt tcagaagaag cggctttgaa gaccttgcaa
    26161 gaccagatgg ctgcattgac agaaagatta gaagccatca aatctcaagg agagcaggca
    26221 cgtattcagg agcaaggctt gtccctcgct tatcagcaaa ctagtcagca agttgaagaa
    26281 ctggaaactc tttggaaact ccaagaagag gaaatagatc gtctttctga gggagattgg
    26341 caagcggata aggaaaaatg tcaagagagc cttgctacta tcgccagtga aaagcaaaat
    26401 ctggaagctg agattgaaga aattaagtct aataaaaacg ccatccaaga acgctatcaa
    26461 aatttgcagg aagaggtggc gcaagctcgc ttgcttaaga cagaactgca agggcaaaaa
    26521 cgttatgaag tagctgatat tgagcgttta ggcaaggaat tggacaatct taatatcgaa
    26581 caagaagaaa ttcagcgcat gctccaagaa aaagttgaca atcttgagaa ggttgataca
    26641 gaattgctca gtcaacaggc ggaagaatcc aaaactcaga aaacaaatct ccaacaaggt
    26701 ttgattcgca agcagtttga gttggatgat atagaaggtc aactggatga tattgccagt
    26761 cacttggatc aagctcgcca gcagaatgag gagtggattc gcaagcaaac acgtgctgaa
    26821 gccaagaaag aaaaggtcag cgagcgcttg cgccatctac aaaatcaatt aacagaccag
    26881 taccagatta gctatactga agcactagaa aaggcacatg aattggaaaa cctcaatctg
    26941 gcagagcaag aggtgcagga tttagagaag gctattcgct cattgggacc tgtcaacttg
    27001 gaagctattg accagtacga agaagttcac aaccgtctgg actttctaaa tagtcagcga
    27061 gatgatattt tgtcagcgaa aaatctgctc cttgaaacca ttacagagat gaatgatgag
    27121 gtcaaggaac gctttaaatc aacctttgaa gctattcgtg agtcctttaa agtgaccttc
    27181 aagcagatgt ttggcggagg tcaggcagac ttgatattga ctgagggcga ccttttaaca
    27241 gctggtgtgg agatttctgt tcaacctcca ggtaagaaaa tccagtcgct taacctcatg
    27301 agtggtggtg aaaaagctct atcggctctt gccttgcttt tctccattat tcgtgtcaag
    27361 accattcctt ttgtcatctt ggatgaggtg gaagctgcgc tggatgaagc caatgttaaa
    27421 cgttttgggg attacctcaa ccgctttgac aaggacagcc agtttatcgt tgtaacccac
    27481 cgtaagggaa ccatggcagc ggctgattcc atctatggag tgaccatgca agaatcgggt
    27541 gtttcaaaga ttgtttcagt taagttaaaa gatttagaaa gtattgaagg atgacaatta
    27601 aactagtagc aacggatatg gacggaacct tcctagatgg gaatggacgc tttgatatgg
    27661 atcgtctcaa gtctctcttg gcttcctaca aggaaaaagg gatttacttt gcggtggctt
    27721 cgggtcgggg atttctgtct ctggaaaaat tatttgctga tgttcgtgat gacattattt
    27781 tcatcgcgga aaatggcagt ttggtagagt atcaaggtca ggacttgtat gaagcgacta
    27841 tgtctcgtga cttttatctg gcaacttttg aaaagctgaa aacgtcacct tatgtagata
    27901 tcaataaact gctcttgacg ggtaagaagg gttcatatgt tctagatacg gttgatgaga
    27961 cctatttgaa agtgagtcag cattataatg aaaatatcca aaaagtagcg agtttggaag
    28021 atatcacaga tgacattttc aaatttacaa ccaacttcac agaagaaacg ctagaagctg
    28081 gtgaagcttg ggttaatgaa catgtccctg gtgttaaggc catgacaact ggctttgaat
    28141 ctattgatat tgttctggac tatgtcgata agggtgtagc tattgttgaa ttagctaaaa
    28201 aacttgctat cacaatggat caggtcatgg cttttggaga caatcttaat gacttacata
    28261 tgatgcaggt tgtgggacat cctgtagctc ctgaaaatgc acgacctgaa attttagaat
    28321 tagcaaagac tgtgattggt aaccataagg aacggtcggt tatagcttat atggagggct
    28381 tataatggca gatataaaat tgattgcatt ggacttggac gggaccttgc tgactactga
    28441 taaaaggctg acggatcgta ccaaggaaac cttgaaagct gcgcgtgatc gtggtatcaa
    28501 ggtcgtattg acaactggtc gtcccttaaa agccatggat ttctttctcc atgagttagg
    28561 gactgacggt caggaagatg agtataccat tacttttaat ggtggattag ttcagaaaaa
    28621 tacaggagaa atccttgata aaacagtctt ttcatatgat gatgtggcac gtttgtatga
    28681 agaaacagag aaattatcac tgcctcttga tgccatctca gaaggaacag tttatcaaat
    28741 ccaatcggac caagaaagtc tttatgccaa attcaatcca gctttgacct ttgttccagt
    28801 ggactttgaa gacttatcta gtcaaatgac ctacaacaaa tgcgtgactg cctttgctca
    28861 agaacccttg gatgcagcca ttcagaagat ttctccagaa ttgtttgacc aatatgaaat
    28921 ctttaaatca cgtgaaatgt tgctagaatg gtcaccaaag aatgttcata aagcaacagg
    28981 tttggcaaaa ctaatcagcc atcttggaat cgaccaaagt caagtgatgg cttgtggtga
    29041 cgaggccaat gacctctcta tgattgaatg ggcaggtctt ggtgttgcta tgcaaaacgc
    29101 tgttcctgaa gtaaaggcag ccgcaaatgt agtgacgccg atgaccaacg atgaggaagc
    29161 tgtcgcctgg gctatcgaag aatatgtgct aaaggagaac taagatatgg gattgtttga
    29221 ccgtctattc ggaaaaaaag aagaacctaa aatcgaagaa gttgtaaaag aagctctgga
    29281 aaatcttgat ttgtctgaag atgttgatcc taccttcaca gaagttgagg aagtttctca
    29341 ggaagaagca gaggttgaaa ttgttgaaca agctgtgttc caagaagagg aaatccaaga
    29401 cacagttgaa gaaagtctgg atttagagcc agttgtagaa gtttctcaaa aagaagtcga
    29461 agaatttcca cactcagaag aagggaatac tgagtttcta gagactatag aagaaaataa
    29521 ttctgaagtt cttgaaccag aaaggcctca agcagaagaa accgttcagg aaaaatatga
    29581 ccgcagtctt aagaaaactc gtacaggttt cggtgcccgc ttgaatgcct tctttgctaa
    29641 cttccgctct gttgacgaag aatttttcga ggaactggaa gaactgctga ttatgagtga
    29701 tgttggtgtc caagtcgctt ctaacttaac ggaggaacta cgttacgaag ccaagcttga
    29761 aaatgccaag aaacctgatg cacttcgtcg tgtcatcatt gagaaattgg ttgagcttta
    29821 tgaaaaggat ggtagctacg atgaaagcat ccacttccaa gataacttga cagttatgct
    29881 ctttgttggt gtgaatggtg ttgggaaaac aacttctatc ggaaaactag cccaccgcta
    29941 caaacaagct ggtaagaagg tcatgctggt tgcagcagat accttccgtg cgggtgcagt
    30001 agctcagcta gctgaatggg gccgacgagt agatgttcca gtagtaactg gacctgaaaa
    30061 agctgatcca gccagcgtgg tctttgatgg tatggaacgt gccgtggctg aaggtatcga
    30121 tattctcatg attgatactg ctggtcgtct gcaaaataag gataacctta tggctgagtt
    30181 ggaaaagatt ggtcgtatta tcaaacgtgt tgtgccagaa gcaccacatg aaaccttctt
    30241 ggcacttgat gcatcaacag gtcaaaatgc cctagtacag gccaaagaat tttcgaaaat
    30301 cacaccttta acgggaattg ttttgactaa gattgatgga actgctcgag gaggtgtggt
    30361 tctagccatt cgtgaagaac tcaatattcc tgtaaaattg attggttttg gtgaaaaaat
    30421 cgatgatatt ggagagttta actcagaaaa ctttatgaaa ggtctcttgg aaggtttaat
    30481 ctaatcagaa gcaaaaatcc tgcaaggcgt aaacttgcag gaaatttttt tattctaagc
    30541 gaccatcttg acgataggtg atatctggtt gccaagtcca tttggcaccg aatttttcaa
    30601 gtaggtcaaa gctggcttga ggtcccatgc ttccagcttt atagtcatga agtggggcac
    30661 cattttcagc ccagagcttt tcaatacggt caatcaactt ccatgacgca caaacttcat
    30721 cccagtggct aaagttagtt gagttgttat ttaggacatc ataaatcaat ttttcgtatg
    30781 gttctggaga agcaccagtt gcagtcgcat ctgtacggta atcaagtgag ttaggagcca
    30841 agttaaattc ttctcctact tgcttcccat ttaggctaag agagaagcct tctgttggtt
    30901 gaatatagat ggtcaaaata tttggagcaa gtggttctcc aaagatagaa tccatttgtt
    30961 taaagacgat gttgacatga gttccttttt cagtcagtcg tttacctgta cggaaaaaga
    31021 aaggaacacc acggaatcga tcgctgtcta caaagaaggc accagatgta aaggtttcag
    31081 ttgttgattc tggattcaca tttggctcgc tacgataaga gatgtatttc atgccatcaa
    31141 tcttaccaga gcggtattgc ccacggataa agtgttcttt gagttcttca tcagttggat
    31201 gatagaggtt tttaaagacc ttaatctttt cagcacgaat ctcgtctttt gtgaagcttg
    31261 ctggtttgtc catggcgagg agcgaaagaa gttgtagagt gtggttttgg accatgtcac
    31321 ggagggcacc ggattggtca tagtagccac cacgttcttc tacacccaag cgctccgcaa
    31381 aggtaatttg aacattgtcg ataaaatcct tgttccaaac gttttcaaaa atcaagtttg
    31441 caaagcgaac tgcaaagatg ctttggatca tttccttacc aagataatgg tcgatacgga
    31501 aaatttgttc ttcgtcaaat gttgctagga gttcgtcatt caacttgttt gcagttgcgt
    31561 aatctgtacc aaatggtttt tcaacgatca agcgctcaaa acctttgcca tcgacaatgt
    31621 tttcagattt gaggtgtttg gcaatggttc caaagaactg aggtgccata gacaagaaga
    31681 agagcttatt gtgttcagct tggtattttt cattaagctc agcttgtaat tgacgcaaag
    31741 caatataatg ttccgaatca ttgacatcat ggctttgata gtagaagtgg ctagcaaatt
    31801 cttgggcttg ctcggtacta tctgccaaat caaggatgga ctcgacaact acagattcaa
    31861 aatattcctt actccaaggt ctacgggcag ttccaataac ggcaaagtgc ttggaaagat
    31921 tgccggattt atatagtcta aaaagggaag ggtagagctt gcgtttagcc aggtctccac
    31981 tcgcaccgaa aattgtaaca ataaccttag atgacatcta gctacctaat ttctattttt
    32041 attcctagtc ttgctaggta tgaggaaacc tcatttcata aacttaattc taacataatt
    32101 ttccgaaaaa tcaaaaattc caatacgagg tagaaaaact gcaaggaaat ccttacagtt
    32161 tgagtttaga cgtttaagac cttatctaag aactctttca gacgagggtg ttgtgggtta
    32221 tcaaagattt ggtcaggtgt tccgtcttca aggaactcgc catctgcagt aaagataacg
    32281 cggttggcaa cctgacgagc aaatcccatc tcatgggtta cgataatcat ggtcatgcct
    32341 tgctcagcca attccttcat aacgttaagt acgtctccaa ccatctcagg gtcaagggca
    32401 gaagttggtt catcgaagag catgatgtct ggattcattg ctaggccacg agctatggct
    32461 acacgttgtt tttgaccacc tgataggcta tctggattgg cattagcttt atctgctagt
    32521 ccaacctttt caagcaactc cattcccaat ttctcagctt cttccttagt catcaacttg
    32581 tgctcaatag gagcaaaggt gatgttgtcc aatacagaca tatgagggaa gaggttgaag
    32641 tgttggaata ccatgccgat attttcacgg acgtggtcaa cattggttgt tttttcagtt
    32701 aaatcatagc cgttcacagt gatgtgaccg ctagtgactt cttctaaaag attgaggcta
    32761 cggaggaaag ttgacttacc agaacctgaa ggaccgatga tacaaacaac atctccttca
    32821 tagaacttag tcgtaattcc ttttaggact tcattttttc catagtgctt gtgtaaatca
    32881 tttacatcaa tttttaattt tgccattaac gaatcctctt ttctaagcgt ttcgctagtc
    32941 tagtcaaaag tgtgataatt acaagataga agatagcaag gattgcatac atcttgaaac
    33001 tttggtagtt acgagcaatg ataatcttac cagtttggaa gagttcaacc aaaccgatag
    33061 cagatacgat agttgtatct ttaagagcga taacgaattg gttgacaaag tttggcaaca
    33121 tcaatttagt tgcttgtggc aagataatct tacgcatggt ttttccataa gagataccca
    33181 agcttcggct ggcttccatt tggccaactg gaacggcctg aataccacca cgaacgattt
    33241 cagcgatata agcagccgca ttgagtgaga gggcaatggt tccagctaca aagtcgttaa
    33301 ttgggctttg ttggcctgtg atagactcga tgaagtttgg aattccccag aagatgaagg
    33361 ctgcaagaat catcaatgga ataccacgaa taacgtcaac gaaaatctca gagatgacgc
    33421 gaagagattt gtatgggcta acgctaaaca taccgaagat aattccgatg acaatggcaa
    33481 tagcaaatga gataagagct agagcaagag tgataccaag accgctaagg agttgtttgt
    33541 agttgttttg aagcaagccc cagagcgttg tttcgtcaac agtacttgtt gaagcagttg
    33601 aagattcgct agctaggtat ttgtcaagaa tcttttggaa ttcaccgttt gctttaaggt
    33661 ttgcaagtcc gttgttgaac atttcaatca gttctggatt tgctcctttt ttaacggcaa
    33721 aggctgtttc accgattgga gttccagaga ttggagtttt caatttttga ccttggctga
    33781 tagaatattt gagaacaggt tcatcatcca taacggcatc aatggcacca gtgtttaaac
    33841 tgtcatacat tgaagaacca tcagcaaagg ttttgatttt gtagccgtat ttgctttgat
    33901 tttctgttag gaaggtttga gaagcagttc cgtttttaac accgactgtc tttcctttta
    33961 gatcttcata agaagcaata ttacttgatt ctttgacacc aagaatggta ttagcagtgt
    34021 agtatgattc tgagaagtca aaagttgcct tacgagcatc tgtgacagac ataccagcga
    34081 tgataccatc ggcttgacca gcttggacag cactgatagc agcatcaaaa ccagggttgg
    34141 tgatttcaat ttcaaaacct tggtctttag cgattgcctt aatcaattcc atatcaatac
    34201 cagtgtattg gttgcttgaa ttttggaaaa caaaaggggc aaaagaagaa tcgctggcaa
    34261 tgatatattt agccttaaca ggaatagctt ttaatcctgc gagagtagtt gtagttggca
    34321 ctgctgaaga tgatgaagca gtccatttct tgataatttt atcaagacta ccatcttttt
    34381 tcatttcaga caaggcttgg ttaaattcag taaccaggtg ctcgtattta cttccttttt
    34441 tcacaccgaa agcaaaactt cctacagctt caccatccat ttcaatatgg aggtcttgac
    34501 cttggttaat ggcatattcg ataacaggtt tgtcatccat catggcatcg atggcaccag
    34561 cactcaagct gttgttcatt aaatcaccag tgtcaaatgt tttaatagta aagccatatt
    34621 tatctttgat tgtttcaagg aaacgttgag cggcagttcc gtttttaaca ccaacggttt
    34681 tgccagttaa ttggtcgtac ttgctaattt tgtgtgactt tgtagtagca atgacaactt
    34741 ttgtatcata gtaagtatca gacatggtga agactttttc acgttcttta gtctttgtca
    34801 tccctgccat gatagcgtcg gcttgcccag cttgaaccgc attgactgct gcgtcaaatc
    34861 caggatagga catctgaatg ttccagcctt taatctcagc gactttgtta ataatgtcaa
    34921 catcaattcc tttataagtt tgatctgaat ctttaaactc aaaaggtgca taggcggtat
    34981 cagaaacaat cttaatcgtt tctgctttgg caatacctaa tgagaaaatt gggaataaaa
    35041 ttagcaaaaa tgctagaaat tttttcttca tttttagtct ccttttccga atattctctc
    35101 attatatcag aaaaagtaaa aaaaggcaaa ttgttatatt tttcgtgtca gaaaatataa
    35161 cattgatttt tccttttctt tcttgaattg ctattaaaaa gtgctataat aatagtatat
    35221 atagaagaaa agaggacggg gatatgaaga acaaaagaat atttaaagac ttccaagctt
    35281 caaaaatgag tttaaacatt tacacaagcc ccttgttagc ctttgttttt gtcttcatag
    35341 gagagtttgt ggcttttact ttgtatggta ttggcttgtt agctctcatc ggacttgcta
    35401 gaaattttgg agaggctggt caaaatcttg caacctactt gcagaccttg catcagagct
    35461 tgacggataa aacaagtgac tttcgtttaa ttttaggatt actggccttt ggttttattc
    35521 ttaacactgt gttcagatgg acaagaaaag ttgagaaaag acctattcga accttgggat
    35581 tttatagaga gaatttcctc agcaatcttc tgaaaggatt tagtctaggc ttggcacttt
    35641 ttcttctgac cttgttaggt ttagtggtct taggtcaata tcgtttggaa tccattcact
    35701 tgaatcctta ttctcttgcc tttgtcgtct ttactatccc attttggatt ttacagggga
    35761 cagcagaaga agtggtggcc cgtgcttggc tacttcctca attggcctca agaaccaatc
    35821 taaaactagc tattcttata tctagcctgt tctttaccct gcttcatatg ggcaattctg
    35881 gcctcacccc tctatctcta gtaaatctct ttttattcgg agttgccatg gctctttatc
    35941 ttctcaaaac tgatacagtt tggggtgttg caggtattca tggtgcttgg aattttgctc
    36001 agggtaatct ctttgggatt ttagttagtg gtcaaccgtc aggaacgtct ctgatgacct
    36061 ttttaccaca aggcaatcaa gattggctat caggtggttc ttttggcata gaaggttcca
    36121 ttatgacaag tctggtatta ctactgctga ttgtctatct tgctaataaa ttaaagaaag
    36181 aaaatgaaag gatgtgactt cggtccgtcc ttttcttcgt gaaaatacta taagtatgct
    36241 aaaataggaa tagcacatgg agagaggatt cttatgatca atcacattac agataatcaa
    36301 tttaaactag tatcaaaata tcaaccatca ggagatcaac cccaagctat cgagcagttg
    36361 gtggataaca ttgagggggg agaaaaagct cagattctga tgggggcgac tggaacaggg
    36421 aagacctata ctatgagtca ggtcatttct aaagtcaata aaccaactct ggttattgcc
    36481 cacaataaaa ctctggctgg tcagctctat ggggagttta aggaattttt ccctgaaaat
    36541 gcagttgagt atttcgtatc ctactatgat tattaccagc cagaggccta tgtcccttct
    36601 agcgatacct atattgagaa ggatagttct gtcaatgacg agattgacaa gcttcgccac
    36661 tcagctacct cagccctttt ggagcgtaat gatgttattg tcgtggcctc agtctcttgt
    36721 atctatggtt tgggttcgcc caaggaatac gctgatagtg tcgttagtct ccgtcctggt
    36781 ctagagattt ctcgtgataa actcttgaat gacttggtcg atattcagtt tgaacgtaat
    36841 gatattgatt tccaacgcgg aagatttcgc gttcgtgggg atgtggtaga gattttccca
    36901 gcttcccgag atgaacatgc ctttcgagta gaattttttg gagacgaaat tgaccgtatc
    36961 cgtgaggttg aggctctgac aggtcaggta ttgggagagg tggatcattt ggcgattttc
    37021 ccagctactc actttgtgac caatgacgac catatggaag ttgccgttgc caagattcaa
    37081 gcagaattag aagagcagtt agctgtcttt gagaaggaag gtaaattgct tgaagcccag
    37141 cgcttgaaac aacggacaga gtacgatatc gaaatgctgc gcgagatggg ctatacaaat
    37201 ggggttgaaa attattctcg ccacatggat ggacgtagtg aaggtgagcc tccttatacg
    37261 cttctcgact ttttcccaga tgattttttg attatgattg acgagagtca tatgactatg
    37321 ggacaaataa aaggcatgta caatggagac cgttcgcgta aggaaatgct agtaaattat
    37381 ggtttccgtt taccgtctgc cttggacaat cgtcctctcc gtcgtgagga gtttgaaagc
    37441 catgtgcatc agattgttta cgtatcagcg acacctggtg actatgaaaa tgaacagact
    37501 gagacggtga ttgagcaaat cattcgaccg acagggcttt tggatcctga ggtggaagtc
    37561 cgtccgacta tgggacagat tgatgatctc ttaggtgaaa tcaatgcccg tgttgaaaag
    37621 aatgaacgaa cctttatcac caccttgacc aagaaaatgg cagaggactt gaccgactat
    37681 ttcaaggaaa tgggcatcaa ggtcaagtac atgcactcgg atatcaagac cttggaacgg
    37741 acggagatta tccgtgatct ccgcttgggt gtctttgatg tcttggttgg aatcaatctc
    37801 cttcgtgaag ggattgacgt tcctgaggtt agcttggttg ccattctcga tgctgacaag
    37861 gaaggtttcc ttcgtaacga gcgtggactc atccagacca ttgggcgtgc cgcccgtaac
    37921 agtgaaggtc atgtcatcat gtatgcagat acggttaccc agtctatgca acgtgctatc
    37981 gatgaaactg cccgccgtcg gaaaattcag atggcctata atgaagagca tggtatcgta
    38041 ccacagacaa tcaagaaaga aatccgtgac ctgattgccg tgaccaaggc agttgctaag
    38101 gaagaggaca aggaagtcga catcaatagc ctcaacaaac aagagcgcaa agaactcgtc
    38161 aagaaactag aaaaacaaat gcaagaagcc gtcgaagtgc ttgactttga actggcggct
    38221 cagatccgtg atatgatgtt ggaagtcaag gccttggatt aggggaatag tatgatttat
    38281 ttaagaaagt taaagaaaga agatttgatg tctttatggg aaatggctta ttcacagctt
    38341 aatccagttt ggaaacagta tgatgctccc tattatgatg attatcagta tttttcaaat
    38401 tttaaagaat tcgaactaca aaaatcagaa tccattttaa gcaactcaaa tcgccttggt
    38461 atttttgttg atgataaact agttgggact gtttcgcgtt attgggtatg taaagaaaca
    38521 agatggatgg aattgggaat tggtatttat gataaaaaat tctggaacac tggtattggg
    38581 aaagttgcta tgttgcagtg gatagatagg acgtttcagg attacttgga gttggagcat
    38641 ctgggtttga caacttggtc aggaaatctt ggtatgatga aacttgctga aaaattaaga
    38701 atgaaaaaag aagctcatat tccaaaagtt cgttattatc aaggtaaata ttttgatagt
    38761 attaaatatg gtattttgag agaagactgg gagaaaataa atgacggtta ttatcaaatc
    38821 aatggaaact cctgaagaga tagaaggcaa atccctcgtt cactggcaaa cgtggagaga
    38881 gtcttatgat gaccttttgc ctgcggaatt tcaggataca atgacattag aaagatgtcg
    38941 attctttagt caaaagtatc cagaaaatac attgattgcg atggatggcg tgaaggtggt
    39001 tggttttatc agttatggca attttcgtga tgagactatt caagctggtg aaattattgc
    39061 tttatatgtt ttaaaagact attatggaaa aggtatcgca caaaagttaa tgaaagcagc
    39121 tttgactgct cttaatcatt tttctgaaat tttcttatgg gtattgaaag ataacaagcg
    39181 cgccattgct ttctatcaaa aaatgggttt tacttttgat ggacaagaaa aaatacttga
    39241 acttggaaag cctataaagg aaaaacgaat ggtgttctat tctaaataat tttaaaaaag
    39301 taaaagataa tatctctggt agtaagtctg aaaatttaat aaattagaaa gcgagtaaat
    39361 ttatgtcccg ttcccaatta acaattttaa caaatatctg tctgattgaa gacctcgaaa
    39421 ctcagcgcgt ggtgatgcag tatcgcgccc ctgaaaacaa tcgctggtct ggttatgcct
    39481 ttcctggagg tcatgtagaa aatgatgagg cttttgcgga gtctgtcatt cgtgaaatct
    39541 acgaagaaac agggttgact atccaaaatc ctcaacttgt cggcattaaa aattggccac
    39601 tagatacagg tgggcgctat attgtcattt gttataaggc gactgagttc tctggtaccc
    39661 ttcaatcttc agaagaggga gaagtttctt gggtgcaaaa agaccagatt ccaaacttaa
    39721 atctggccta tgatatgcta ccattgatgg aaatgatgga agctcccgac aagtcagagt
    39781 ttttctatcc tcgccgtaca gaagacgatt gggaaaagaa aatcttctag tcttttacta
    39841 aataacctag ctgatccaag gcctcctcga tatagtggag gtcttgttgt gtttcggctt
    39901 cgactaggtg gtaatggatg ccatctgtca attcagatag aggtctaaag tcagaatgct
    39961 cgacttgttc tagaaaatgt tgcacatctc tgcgacaaga cagtttaagc aaggtttcaa
    40021 tttctccata aacgggatgg tcaatcaagg tattctggac atgcccacca ttatcgacaa
    40081 tagcaaggag ttcctgaccg atttcttcaa cttcatgttt cactttgaaa agtttgtgaa
    40141 cataaggatt ggtatcaatt tgcttataga tgtagccacg attggtggat aggataggag
    40201 cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat
    40261 gttccgccaa actttggcca ttaagggctt taggagcttc tttcaagagt tggagcaggg
    40321 cttgtttgcg atcttttgtc atagcttttc cttttaacgg cgttttcgaa gcactttata
    40381 gacagctagt gctaatgtat agtctaccat actatggata attgtgccaa atccaactag
    40441 cacaaataga acatagaaca tgttttctac attggtaccc gaagttgcgt aaaaaaggac
    40501 acaggctaat acttcagcaa gggcatgaac aacagccaaa acaaagttga aaacccagga
    40561 agattttggt ttatctaggg tatcggggaa tttttgtagg taaagagctc ctaaagcacc
    40621 aaaagatata tgggaaaaag cccgaaaaac gataaccatg ggatagccag ccatcaaaaa
    40681 tccaaaacta gaggctagga tgacaaaaac tgccatcaag ggcgacaaga acatggctat
    40741 aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg
    40801 cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg gctgtcattg tcataaattg
    40861 tgtctttttc cgtgtattca caagaatctc ctttttaact gcatatacac tagtatggta
    40921 caataaacca gacaataaag caagaattta cttgggttta tagatcattt tttagttaaa
    40981 agttatagta gattgaaact agaatagtcc acctctactt ctaaaacatt gttagaaatc
    41041 gatttggctg tcctgatcaa tttgtcctgt tcttatttcg ttttacttat agtaaagatt
    41101 tcattaaaaa gaaactgtat agagcaaaat ctccaccttc aggtttgaaa gcggagattg
    41161 tttttatttt ttcaaggttt gtagtcgtgg aacaatggct agggttagaa ttgcagaaat
    41221 gaccaattca gcaattgaat ttgttgagat aacggttgcc agaagaagtt ggatatttcc
    41281 gttataaaca tttccaaata ggaagaagat tcctccaagg acaaagatag tatttgtcaa
    41341 ggaaccaaga gccccagcta aaatcagacc agtcttgttt ttcatcagtt tatagactaa
    41401 gtaaggagtt aaaccaatca aaatacgtgg gacaatggca atgatagctg agtagatgtt
    41461 tccgtttggt acgaagggag agaagaggta gcttgtcggt agaatcgtaa tcgtgttaac
    41521 cgtcaagcta agtaatccca tcaaaaatcc aagtgtaacc ccaactcgtg gaccataaat
    41581 aatgctggca ataatgacag gaatatgaac aatggtcggt ttgattggaa atggaaaaag
    41641 gttaaagata agtgagctca gaaagtgtat cacgagcatg gtagcaaaaa agatagcaat
    41701 gggtgcaata ttagagcgtt ttttcatcga tagtttcctt tattctttct aaaataattg
    41761 tgaggtcagc taaagctcct cgtccgtggt ctccacaagc tagtagggat tccttaggag
    41821 caatcagctg atagccgtag gtttctaatg ttttcagatt attctgagtt actggatggt
    41881 catacatttt tgtattcata gcaggagcta ttagtttggg aatatgactt ggtagggcta
    41941 gagctgtact ggttaccatg ttgtccgcaa atccgtgagc tagttttgca atagtgttag
    42001 cagttgcagg taccacgata aataaatctg ctttttttcc aagttcgata tgattgacct
    42061 gatcaggata gggttccttc atgacatcca agtggacagg attctgtgag agtacctgta
    42121 gtgtcaaagg ttggataaac tctgtagcag cctgagtcat taagacagtg acttgatggc
    42181 cttgtttttt tagagaactg actaaatctg ccgacttata agaggcgatt gaacccgtta
    42241 cagccaagag aatgtttgcc atagttttcc tttctaagaa tgataggctt gaattttttc
    42301 aaggaggagt tctgcaattt cttctttagt ctggactgtt tgaagctgat ttttctcaac
    42361 aaatatagct cggtgctgac ctgctgaaat ttgagtcagg tcattcgcga tgattaaatc
    42421 tgcttgattc ttgataagac tttttcgtgc aatgtcaacc agatgatctt cggtaacatc
    42481 aaccagcagt ttgaaaccaa tcagatgaat agtaggattc cattccttga ctagggatat
    42541 gattttgggt gtctttttaa ggaacaaaac ctgaacctca tcagttgaag aaatcttggc
    42601 ctgatgattc tgcttgctta aaaattcttt tagattggag ctagcctgaa cttcctcaag
    42661 ccctgtcata taaacaggag tgtagtcaga aacagccatt gagtggatca agacctgata
    42721 atcctgaaca cgttcttgca tttctattag aaggtccttg gtattggtaa tttctcgaat
    42781 acttaggtta ggatgaggct ctggcttcag agctcgtttt gtcgtaatta aacaaacttc
    42841 atgccctgca gaaagcaaag tctctgtgat aattttcccc aagtgacctg tagaatggtt
    42901 agtgatagag cggacgctat cgatagcttc actggtaccg cccgatgtaa ctaaaatttt
    42961 catagcacta ttgtacacaa aaataagcgg taagtaaaat gaaagtgata aatttttggt
    43021 aaaaacgaag atttattata gtttcaaact ataaagccat ataaaatgta agaaaggact
    43081 ctaaaagtct taaaaacaga gatatttacg aacgtttaga gagttttagg atgttaaaaa
    43141 tcttgttttg tgatataatg aattatcata taagaggtta gaggaatttt gaatgaaaac
    43201 agatattgaa atcgcacaga gtattgagtt gaagccaatt gttgatgttg tagagaaact
    43261 tggtatttct tacgacgatt tggagttgta cggaaagtac aaggctaaac tcagctttga
    43321 taaaattcgt gcagttgaga gcaatccagt cggtaaattg atcttggtta ctgccatcaa
    43381 cccaacacct gcaggtgaag gaaagtcgac gcttaccatt ggtcttgcgg atgccttgaa
    43441 caagattggc aagaaaacca tgattgctat ccgcgaaccg tctcttggtc cagtcatggg
    43501 gatcaagggt ggtgctgctg gtggtgggta tgcacaagtt ctgccaatgg aagacatcaa
    43561 cctccacttt actggagata tgcatgctat tacaactgcc aacaatgccc tttctgcctt
    43621 gattgacaac cacttgcacc aagggaatga gctgggaatt gatcaacgtc gtatcctctg
    43681 gaaacgcgtt gtggacttga acgaccgtgc gctccgccat gtgactgttg gtcttggtgg
    43741 tcctctaaac ggtattccac gtgaggatgg ttttgatatt acagttgctt cagaaatcat
    43801 ggcaattctt tgcttggcaa cggacatcga ggacttgaaa cgtcgtttgg cgaatatcgt
    43861 tattggttat cgctatgacc gtacgcctgt ttctataggt gatttgcagg ttgagggtgc
    43921 cttggctttg attttgaagg atgctattaa gccaaacttg gttcagacaa tttacggtac
    43981 acctgccttt gtacacggtg gtccatttgc caatatcgct catggctgta actctgtttt
    44041 ggcgacgaca acggcccttc acttggctga ttacactgtt actgaagctg gttttggtgc
    44101 ggaccttggt gctgagaaat tccttgatat caagacacca aacttgccaa catctccaga
    44161 tgcagttgtt attgtcgcaa cccttcgtgc ccttaagatg aatggtggtg tggctaaaga
    44221 cgctctgact gaagaaaatg tagaggcagt tcgtgcaggt tttgctaact tgaaacgcca
    44281 cgttgaaaat atccgtaagt tcggtattcc agcagttgta gctattaacg aatttgtatc
    44341 tgatacagaa gctgaaattg cagtcttaaa agaactctgt gcctcaatcg atgtaccagt
    44401 tgaattggct agtgtctggg ctgatggagc agaaggtgga gtagcacttg ccgaaacagt
    44461 tgttaagaca attgctgaaa atccagctaa ctataaacgt ttgtatgata atgacctttc
    44521 tgtccaagaa aagattgaaa aaattgtcac tgaaatctat cgtggtagca aagtgaactt
    44581 tgagaagaaa gctcaaacac aaattgctca aatcgttcaa aacggttggg acaaattgcc
    44641 aatttgtatg gctaaaactc aatacagttt ctcagacaat ccaaatgcgc ttggagcacc
    44701 agaaaacttt gaaattacca ttcgtgaatt ggtaccaaaa ttaggtgcag gcttcatcgt
    44761 tgccttaact ggtgatgtta tgaccatgcc aggtcttcca aaacgtccag cagctctcaa
    44821 catggatgtt gaaagcgatg gaactgtact aggcttgttc tagtggattg aaattgactt
    44881 taagtgagtt tggaaataat atccaagctc attttttctc agactgcaag cagttcatca
    44941 ataagattta tactcttcga aaatctcttc aaactacgtc agcttcacct tgccgtaggt
    45001 atatgatact gactctgtca gttctatcca caacctcaaa acagtatttt gagcaacctg
    45061 cggctagctt cctagtttgc tctttgattt tcattgagta taagtagata gaaaagttat
    45121 atactatcta ttgaaaatat tataaatcag atacaaagac aggtgaaacc ttctgtgtta
    45181 tactagagat atgttagatt taaaagaata cggtatcgtc atgtggccgg aggagaaagt
    45241 catttctttc cgtgagaaac ttctcgcttg gtatgatgaa aacaaaagag atttgccttg
    45301 gaggagaagt aaaaatcctt atcacatctg ggtatctgaa atcatgcttc agcagaccag
    45361 ggtggataca gttatccctt actacgaaag attcctggac tggtttccaa ctgtcgaaag
    45421 tctggcaact gcgcctgagg agagtttact gaaagcttgg gagggcttgg gctattattc
    45481 tcgagttcgc aatatgcagg ctgcagccca gcagattatg actgactttg gtggccaatt
    45541 tccaaatacc tatgaaggaa tttccagctt gaaagggatt ggaccttaca cagcaggagc
    45601 catttccagt attgctttta acttgcctga gccagctgta gatggtaatg tcatgcgggt
    45661 cttggcgcgt ctgtttgaag tcaaccacga tattgggatt ccaagtaatc gaaaaatttt
    45721 tcaggcaatg atggagatct tgattaatcc ggatcgtccg ggtgatttta atcaagcctt
    45781 gatggactta gggtctgata ttgagtctcc tgtaaatccc agacctgaag aaagcccagt
    45841 caaggacttt agtgcggcat atcagaatgg aaccatggac cgttatccaa ttaaatctcc
    45901 taagaaaaag ccggttccta tttatcttaa agccttagtt gtgaaaaatt ctcaaggaca
    45961 atttttactt gaaaaaaatg aaagcgaaaa gctcttggca ggtttttggc atttcccctt
    46021 tatagaagtt gataactttt cgcaagaaga gcagtttgac ctctttcatc aggttgcgga
    46081 agaaagtgtg aactttggcc ccagtccaga agagagtttc cagcaggact atgacctaga
    46141 tgttgattgg cttgatgttt gttttgatac agtccagcat gtttttagtc atcgaaaatg
    46201 gcatgtacag attgtagcag gtcaggtgag tgacttccat gatttttcag atagggaagt
    46261 tcgttggctt tcaccagaag aattcaagaa ttacccactt gccaaacccc aacaaaaaat
    46321 ctggcaggct tatgcacaag ccaacttaga cagtagccaa gactagctat tgtgtcttct
    46381 gactattttt ttggtataat agtggagaaa aaggtgaaca tatgaaaaaa atactaattg
    46441 tagatgatga gaaaccaatc tcggatatta tcaagtttaa tatgaccaag gaaggttacg
    46501 aagttgtaac tgcttttaat ggtcgtgaag cgctagagca atttgaagca gagcaaccag
    46561 atattattat tctggatttg atgcttccag aaattgatgg tttagaagtt gctaagacca
    46621 ttcgtaagac aagcagtgtg cccattctta tgctttcagc caaagatagt gaatttgata
    46681 aggttatcgg tttggaactt ggggcagatg actatgtaac gaaacccttc tccaatcgtg
    46741 agttgcaggc gcgtgttaaa gctcttctgc gtcgttctca acctatgcca gtagatggtc
    46801 aggaagcaga tagtaaacct caacctatcc aaattgggga tttagaaatt gttccagacg
    46861 cctacgtggc taaaaaatat ggcgaagaac tagacttaac ccatcgtgaa tttgagcttt
    46921 tgtatcattt agcatcgcat acaggtcaag tcatcacgcg cgaacacttg cttgagactg
    46981 tctggggtta tgactatttt ggtgatgtcc gtacagttga tgtgactgta cgacgtctgc
    47041 gtgagaagat tgaagatacg cccagccgac cagagtatat cttgacgcgc cgtggtgtag
    47101 ggtattacat gagaaataat gcttgattta ctgaaacaaa ccatttttac cagagatttt
    47161 atctttatcc tgattttgtt aggtttcatc cttgttgtga ccctcttatt actggaaaat
    47221 agacgtgata atattcagtt gaagcaaatc aatcaaaagg ttaaagattt gattgcagga
    47281 gattattcca aggttcttga tatgcaaggt gggtctgaaa tcaccaatat taccaataat
    47341 ttgaatgact tgtcggaggt tattcgtctc actcaggaaa atctagaaca agagagtaag
    47401 aggctaaata gtattctgtt ttatatgaca gatggggttc ttgcgaccaa ccgtcggggt
    47461 cagattatca tgattaatga tacagccaag aagcaactgg ggttggttaa ggaagatgtt
    47521 ctgaatagaa gcattttgga attgctcaag atagaagaaa actatgaatt gcgtgatttg
    47581 attacccaaa gtccagaatt gttgctagat tcccaagata tcaatggcga atatttgaac
    47641 cttcgagttc gctttgcctt gatacgtcga gagtctggct ttatttcagg tttggtggct
    47701 gttttgcatg atacgacgga gcaggagaag gaagaacgag aacgaagact ctttgtttcc
    47761 aatgttagcc atgagttacg gactcctctg actagcgtaa aatcctatct tgaagccttg
    47821 gatgaggggg ctttgtgtga aactgtagca ccagacttta tcaaggtttc tcttgatgag
    47881 accaaccgta tgatgcgcat ggtgacggat ctcctccatc tttcacgtat tgataatgct
    47941 accagtctcc tagatgtgga actgattaac ttcactgctt ttattacctt tatcctcaat
    48001 cgttttgaca agatgaaagg acaggaaaag gagaaaaaat atgagttggt gagagattat
    48061 cccgtcaatt ctatctggat ggaaattgat acagataaga tgacgcaggt tgtcgacaat
    48121 attttaaata atgctattaa gtattcgcca gatgggggta aaatcactgt cagaatgaag
    48181 acaactgaag accagatgat tttatccatt tctgaccacg gtttggggat tcctaagcag
    48241 gatttaccac gtatctttga ccgtttctat cgtgtggatc gtgctagaag tcgtgcacaa
    48301 ggtggtacag gtctaggact gtctatcgct aaagaaatta tcaaacaaca taagggcttt
    48361 atttgggcca agagtgaata cggcaagggt tcaaccttta ccattgtgct cccttatgat
    48421 aaggatgcag tgaaagaaga agtatgggag gatgaagtag aagactagaa tgagtgaaat
    48481 aggctttaaa tacagtattt tagcgtcggg ttccagtgga aattcttttt atctggaaac
    48541 ctcaaaaaag aagcttttag tagatgcagg cttgtctggc aagaaaatta ccagtctgct
    48601 agctgaaatt aaccgtaagc cagaagacct ggatgccatc ttgattaccc atgagcattc
    48661 agatcatatc catggagtag gcgttttggc tcgcaagtat ggtatggatc tttatgccaa
    48721 tgaaaagacc tggcaagcta tggaaaatag taaatatctt ggcaaggtgg attcttcgca
    48781 aaagcatatt tttgaaatgg gtaaaaccaa aacctttgga gatatcgaca tcgagagttt
    48841 tggtgtaagc catgatgcag tcgcaccgca gttctatcgc tttatgaagg atgataagag
    48901 ttttgtcctt ttgacagata caggttatgt cagtgaccgt atggcgggca ttgtcgaaaa
    48961 tgcggatggc tatcttatcg aggccaacca tgatgtagag attttgcgat caggttctta
    49021 cgcttggcga ctcaaacaac gaatcctatc tgaccttggt cacctttcta acgaggacgg
    49081 tgctgaagct atgattcgga cgctaggaaa tcgtactaag aagatttacc ttgggcattt
    49141 atctaaggaa aacaatatca aggaactggc tcatatgacc atggtcaatc agctggctca
    49201 agctgatctg ggagtcggag tagactttaa ggtttatgat acctcaccag ataccgcaac
    49261 accattgaca gagatataga aagaacgctg agaaggtgtt ctttttatat tgactggaca
    49321 cctaaaaagt aatacaatgg tgttaccatt aaaaaaggga gcacaaaaga tgactactat
    49381 tacattaaaa gtttctgaag ctgataaaac atttatgaaa gcaatggcta agtttgaagg
    49441 agtttccctt tcggaactta ttcgcaccaa aactcttgaa gccctagaag atgaatacga
    49501 tgctcgtgtg gcagatttag cctatcaaga gtatttagaa gacttggaaa aaggagttga
    49561 acccattact tgggaagaaa tgatgcatga tttaggcttg aaggatgaat aatttgtata
    49621 aattagttcc aacaagacgt tttatcaagc aattgaaaaa attggaccgt tatacgcaga
    49681 agctaattac aaactattta caaaccaatg ttttggaaga cccaagacga cacggaaagg
    49741 ctttggttgg taatcgcgtt ggtcaatggc gctatagaat tggtaattat cgagttatcg
    49801 tacaaattgt agatgatgaa ttagttgttg ctactctaga agttggtcat cggagagata
    49861 tttattgaat taaagctgag taataacagt atagaaagta aggatagtaa aaatttgaat
    49921 aaaaaatggt tatttgcaga ttattatgat acaacaatta ttttacttgc tttaatctct
    49981 gttattctgg tattacttgg atttgctgag atgattgatt tggacaatcc gccttatagt
    50041 attattgatt tagtaatctg gggtgttttt gtaattgatt atagttggcg cttttttacg
    50101 actaaaagaa aatggcgctt tattcttgaa aatatttttg atttattggc tattctccct
    50161 ttaaatgcta ttttcacagt ttttcgatta gggcgtatct ttcgtttaac taaactaaca
    50221 aaattactga aactgactcg tttacttaga ataattggac ttacaggtaa attagaaaga
    50281 aaaattagta gattcttatg gacaaatggc ctgatttata tcttgtatgt taatatcttt
    50341 attgttctag tagggagttc gattttatcc gttgttgaag aaaaatcctt ctcagatagt
    50401 ctttggtggg ctcttgtgac agtaactact gttggttatg gtgatattgt tccagtttcc
    50461 ctttttggga aatggctagc agttttactg atgcttgtcg gtattggaac aataggggtg
    50521 ctaacaagtg ctttgacgaa cttttttgta aaggataatc cagatgaaca gataaaactt
    50581 gataaactca aagacgaatt atcgagccaa agaatattaa tagagaaaca atctgaaaaa
    50641 atcgaagaac tacattgaat gataaaagac ttagttgaaa aaatatcata aaggtgagac
    50701 aaaacaaaac ttgattcgag gagaaatcaa gtaagtcttg acacaataga acgcatatta
    50761 tcaggtataa aaacttgata ctatgcgttt tatagagaaa taaaataaaa tctgaacaaa
    50821 tcaattagga atttaaagca ttttataaca acgttttaga gtgatggggt gctatttcaa
    50881 cttcaaccta ctataataca gaaaaaaaca actccctgat gattcaagga gttgtctata
    50941 gttaaattag tttttagaag cttcttggaa ttctggattt ttccatgctt cgtcaataat
    51001 agcttgcaat tctttagcag atgcttgcat tttttgagtt tctgcatcgt tcaatggaat
    51061 gtttactgga cgaacgatac catgtgcacc aacaacagct ggttgaccga taaagacatt
    51121 ctcaactccg tattgacctt cttggaatac tgaaagtgga agtactgcgt tttcatcgtc
    51181 aaggattgct ttagtgatac gagcaagggc tactgcgata ccgtagtatg ttgcaccttt
    51241 tttgttgatg attgtgtagg ctgcatcacg aacaccttcg aacaattcaa tcaattcagc
    51301 ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg tttacaccag cgatgttagc
    51361 gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc atgatgtagg cgtgcactga
    51421 acgagcatcc acatccaatt tttcagcaag tgcttgacgg aaacgagctg agtcaagtga
    51481 agtacctgaa ccgataacgc gttctttagg gaaaccagag aatttccaag ttgagtaagt
    51541 caaaacgtca actgggttag cagcaacaag gaagatacct ttgaaaccag attcaacaac
    51601 ttgagttacg attgatttgt tgatagcaag gtttttacct acaaggtcaa gacgagtttc
    51661 acctggtttt tgaggtgcac ctgcagtgat cacaacaagg tcagcgtctg cacagtcaga
    51721 gtattgagct gcatagattt ttttaggtga agtgaaggca agggcgtgac taaggtcaag
    51781 cgcatcacca acagcttttt catgcaattg tggaatttcg ataattccaa gctcttgtgc
    51841 aattccttgg ttaacaagtg caaaagcgta agatgaacct acagcaccat caccgacaag
    51901 gataactttt ttgtgttgtt tagttgaagt cattgtttta aacatctcct taattttatt
    51961 aggggatttt ccctagacaa cttcattcta tcacttttaa aaaactttgt cacgaatatg
    52021 ccttatagtt ctcgatgtaa acgttttagt ggtttagagg ctgaaataga tgggaattta
    52081 tggtataatg ttgttactta ctaattgtga aatgaggcat ttattaatgc aggataaaaa
    52141 tttagtgaat gtcaatctga caaaggagat gaaggcaagt tttatcgact acgccatgag
    52201 tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc ttaaaacctg ttcaccgtcg
    52261 cattctctac ggaatgaatg aattgggtgt gaccccagac aaaccccata aaaaatctgc
    52321 tcgtattaca ggggatgtca tgggtaaata tcacccacac ggggattcct ctatttatga
    52381 agccatggtc cgtatggctc aatggtggag ctaccgttac atgcttgtag atggtcatgg
    52441 gaattttggt tccatggatg gagatagtgc tgccgctcaa cgttataccg aggcacgtat
    52501 gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa aatacagttg atttcgttga
    52561 taactatgat gccaatgaac gggaaccctt ggtcttgcca gcgcgttttc caaacctttt
    52621 ggttaatgga gcaactggta tcgcggttgg gatggcaacc aatattccac ctcataatct
    52681 gggtgaaacc attgatgcag tgaagttggt catggataat cctgaagtga ctaccaagga
    52741 cttgatggaa gtcttgcctg gaccagattt tccaactggt gctcttgtca tggggaaatc
    52801 aggtatccat aaggcttatg aaacaggtaa aggttcgatt gtcctacgtt ctcgtacaga
    52861 gattgaaacg actaagactg gtcgtgagcg tatcgttgta acagaatttc cttatatggt
    52921 caataaaacc aaggtgcatg agcatattgt tcgcttggtt caggaaaaac gcattgaggg
    52981 tatcacggca gtacgtgatg agtcaaaccg tgaaggtgtt cgatttgtta ttgaagtcaa
    53041 gcgcgacgcc tcagccaatg ttattctcaa taacctcttc aaaatgaccc aaatgcaaac
    53101 caattttggt ttcaatatgc tcgctatcca aaatggtata ccgaaaattt tgtctcttcg
    53161 tcagattttg gatgcttata ttgagcacca aaaagaagtg gttgttcgtc gtacacgttt
    53221 tgataaggaa aaagcggaag cgcgcgctca tatcttagaa ggtctcttga ttgcgctaga
    53281 ccatatcgac gaagtgattc gtatcatccg tgctagtgaa acggatgcgg aagctcaagc
    53341 tgagttgatg agcaagttta agctttctga acgtcaaagt caagctatcc ttgatatgcg
    53401 tcttcgtcgt ttaacaggtt tggaacgcga taagattcaa tctgagtatg atgacctctt
    53461 ggctctgatt gcggatttag cagatattct tgctaagcct gaacgtgttt ctcaaattat
    53521 caaagacgaa ttggatgaag ttaaacgtaa attttctgat aaacgccgta cagagttgat
    53581 ggttggacag gtcttgagtc tcgaggatga ggacttgatt gaagaatcgg atgtcttgat
    53641 taccctttct aacagaggct acattaagcg tttggatcag gacgagttca ctgctcaaaa
    53701 acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat gatgactttg ttcgtgagtt
    53761 agtgtcaact agcacccatg atcatctgct cttcttcaca aacaagggac gtgtctatcg
    53821 tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc aaagggctac cagtagtcaa
    53881 tctcttgaaa ttggatgaag acgaaagtat tcagacggtt atcaatgttg agtctgatcg
    53941 cagtgatgat gcttatctct tctttacaac ccgtcacggt attgtgaaga gaactagtgt
    54001 taaggagttt gccaatattc gtcaaaatgg tctcaaagcg ctgaatttaa aggatgaaga
    54061 tgagttaatc aatgtcttgt tggcagaagg agatatggat attatcattg gtaccaagtt
    54121 tggttatgca gttcgcttta atcaatcagc cgttcgtggt atgagccgta tcgccactgg
    54181 tgtgaaaggt gttaaccttc gtgaaggaga cacagttgtt ggtgccagct tgattactga
    54241 tcaagatgag gttcttatta tcacagaaaa aggatatggt aagcgtacag tcgctactga
    54301 atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca gctaaaatta ccgaaaaaaa
    54361 tggcttgctg gccggtctta tgactgttca aggggatgag gatttgatga ttatcactga
    54421 tacaggtgtc ataattcgaa ccaatcttgc caatatttca caaacaggac gtgcaactat
    54481 gggagttaaa gtaatgcgcc tggatcaaga tgctcagata gtgactttca caacggttgc
    54541 ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca gaaggtgaag cataatgtct
    54601 caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc tgacaaatat cctagcagga
    54661 tttctgatat tactgtcact ggctttgatt tttaatactc aaattcgaaa tattttcata
    54721 gtctggaata ccaataagta tcaagttagc caggtatcaa aagaaaaatt agaagaaaat
    54781 caggatacag aaggcaattt tgactttgat tctgtcaaag ctatctcttc ggaagctgtt
    54841 ctaacttctc aatgggatgc tcaaaaatta ccagttattg ggggaattgc aattcctgaa
    54901 ttggaaatga atttgccgat ttttaaagga cttgataatg ttaatctctt ctacggagct
    54961 ggtacaatga aacgcgagca agtaatggga gaaggaaatt atagtctagc tagtcaccat
    55021 atctttggtg ttgataatgc taataaaatg ttattttctc ctttagataa tgctaaaaat
    55081 ggcatgaaga tttatctaac cgataaaaat aaagtttata cttatgaaat acgtgaagtc
    55141 aaacgtgtga caccggatcg tgttgatgaa gttgatgata gagatggggt caatgaaatc
    55201 acattagtaa cctgtgaaga ccttgctgct acagaacgta ttattgtcaa aggtgatttg
    55261 aaagaaacaa aagattattc acaaacatct aatgaaatcc taacagcttt caatcaacca
    55321 tataaacaat tttattaata caaatcagtg aaatccatga tttcactgat tttttaagat
    55381 tttcat
//
LOCUS       DAVHSH010000008        54328 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000008 DAVHSH010000000
VERSION     DAVHSH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.008"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(120..830)
                     /locus_tag="VVR08_000590"
     CDS             complement(120..830)
                     /locus_tag="VVR08_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU6074548.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(833..2524)
                     /locus_tag="VVR08_000591"
     CDS             complement(833..2524)
                     /locus_tag="VVR08_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6074549.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(2536..3546)
                     /locus_tag="VVR08_000592"
     CDS             complement(2536..3546)
                     /locus_tag="VVR08_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074550.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLNPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(3649..4716)
                     /locus_tag="VVR08_000593"
     CDS             complement(3649..4716)
                     /locus_tag="VVR08_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6074551.1"
                     /translation="MKKMKVWSTVLTTGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGTPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESTVVKVLDKENAIQYGMIWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            complement(4741..5400)
                     /locus_tag="VVR08_000594"
     CDS             complement(4741..5400)
                     /locus_tag="VVR08_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU6074552.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPIITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(5580..5894)
                     /locus_tag="VVR08_000595"
                     /pseudo
     CDS             complement(5580..5894)
                     /locus_tag="VVR08_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(6142..6438)
                     /locus_tag="VVR08_000596"
     CDS             complement(6142..6438)
                     /locus_tag="VVR08_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074553.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVYILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(6422..8581)
                     /gene="pfbA"
                     /locus_tag="VVR08_000597"
     CDS             complement(6422..8581)
                     /gene="pfbA"
                     /locus_tag="VVR08_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU6074554.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSYTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKIEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(9712..10938)
                     /locus_tag="VVR08_000598"
     CDS             complement(9712..10938)
                     /locus_tag="VVR08_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU6074555.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGANLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(10981..11673)
                     /locus_tag="VVR08_000599"
     CDS             complement(10981..11673)
                     /locus_tag="VVR08_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6074556.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALIL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(11846..13597)
                     /locus_tag="VVR08_000600"
     CDS             complement(11846..13597)
                     /locus_tag="VVR08_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074557.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLVAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(13587..15332)
                     /locus_tag="VVR08_000601"
     CDS             complement(13587..15332)
                     /locus_tag="VVR08_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074558.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVVEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILEPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(15538..15915)
                     /locus_tag="VVR08_000602"
     CDS             complement(15538..15915)
                     /locus_tag="VVR08_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU6074559.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(15987..16443)
                     /locus_tag="VVR08_000603"
                     /pseudo
     CDS             complement(15987..16443)
                     /locus_tag="VVR08_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            16577..17404
                     /gene="xth"
                     /locus_tag="VVR08_000604"
     CDS             16577..17404
                     /gene="xth"
                     /locus_tag="VVR08_000604"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU6074560.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            17416..17559
                     /locus_tag="VVR08_000605"
     CDS             17416..17559
                     /locus_tag="VVR08_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6074561.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            17670..17798
                     /locus_tag="VVR08_000606"
     CDS             17670..17798
                     /locus_tag="VVR08_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU6074562.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     regulatory      18181..18276
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18676..19257
                     /locus_tag="VVR08_000607"
     CDS             18676..19257
                     /locus_tag="VVR08_000607"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU6074563.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            19257..20519
                     /locus_tag="VVR08_000608"
     CDS             19257..20519
                     /locus_tag="VVR08_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU6074564.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(20606..21472)
                     /locus_tag="VVR08_000609"
     CDS             complement(20606..21472)
                     /locus_tag="VVR08_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEU6074565.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(21459..22229)
                     /locus_tag="VVR08_000610"
     CDS             complement(21459..22229)
                     /locus_tag="VVR08_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6074566.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(22255..23109)
                     /locus_tag="VVR08_000611"
     CDS             complement(22255..23109)
                     /locus_tag="VVR08_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEU6074567.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(23266..23670)
                     /locus_tag="VVR08_000612"
     CDS             complement(23266..23670)
                     /locus_tag="VVR08_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU6074568.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(23740..25221)
                     /locus_tag="VVR08_000613"
     CDS             complement(23740..25221)
                     /locus_tag="VVR08_000613"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6074569.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(25240..26418)
                     /locus_tag="VVR08_000614"
     CDS             complement(25240..26418)
                     /locus_tag="VVR08_000614"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU6074570.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAVRKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQKAGHVIDKGFDFYVYGNIPNGSGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            26582..27589
                     /gene="galR"
                     /locus_tag="VVR08_000615"
     CDS             26582..27589
                     /gene="galR"
                     /locus_tag="VVR08_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU6074571.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAI
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEARINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(27636..28675)
                     /locus_tag="VVR08_000616"
                     /pseudo
     CDS             complement(27636..28675)
                     /locus_tag="VVR08_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
     gene            complement(28676..29029)
                     /locus_tag="VVR08_000617"
     CDS             complement(28676..29029)
                     /locus_tag="VVR08_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU6074572.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(29273..30163)
                     /locus_tag="VVR08_000618"
     CDS             complement(29273..30163)
                     /locus_tag="VVR08_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU6074573.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            30296..30832
                     /locus_tag="VVR08_000619"
     CDS             30296..30832
                     /locus_tag="VVR08_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6074574.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(30998..31804)
                     /locus_tag="VVR08_000620"
     CDS             complement(30998..31804)
                     /locus_tag="VVR08_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU6074575.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
     gene            complement(32149..33669)
                     /locus_tag="VVR08_000621"
     CDS             complement(32149..33669)
                     /locus_tag="VVR08_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU6074576.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(33662..34390)
                     /locus_tag="VVR08_000622"
     CDS             complement(33662..34390)
                     /locus_tag="VVR08_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074577.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(34405..35169)
                     /locus_tag="VVR08_000623"
     CDS             complement(34405..35169)
                     /locus_tag="VVR08_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU6074578.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(35173..35616)
                     /locus_tag="VVR08_000624"
     CDS             complement(35173..35616)
                     /locus_tag="VVR08_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6074579.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(36298..36594)
                     /locus_tag="VVR08_000625"
     CDS             complement(36298..36594)
                     /locus_tag="VVR08_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6074580.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHLAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(36616..37680)
                     /gene="pepA"
                     /locus_tag="VVR08_000626"
     CDS             complement(36616..37680)
                     /gene="pepA"
                     /locus_tag="VVR08_000626"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU6074581.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38081..38782
                     /gene="galE"
                     /locus_tag="VVR08_000627"
     CDS             38081..38782
                     /gene="galE"
                     /locus_tag="VVR08_000627"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6074582.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHYTGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            39205..40164
                     /locus_tag="VVR08_000628"
     CDS             39205..40164
                     /locus_tag="VVR08_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074583.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            40154..41110
                     /locus_tag="VVR08_000629"
     CDS             40154..41110
                     /locus_tag="VVR08_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU6074584.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            41107..41859
                     /locus_tag="VVR08_000630"
     CDS             41107..41859
                     /locus_tag="VVR08_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6074585.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELNILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            41955..42920
                     /locus_tag="VVR08_000631"
     CDS             41955..42920
                     /locus_tag="VVR08_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6074586.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(43145..43387)
                     /gene="yidD"
                     /locus_tag="VVR08_000632"
     CDS             complement(43145..43387)
                     /gene="yidD"
                     /locus_tag="VVR08_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU6074587.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(43387..44109)
                     /locus_tag="VVR08_000633"
     CDS             complement(43387..44109)
                     /locus_tag="VVR08_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6074588.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(44096..44665)
                     /locus_tag="VVR08_000634"
     CDS             complement(44096..44665)
                     /locus_tag="VVR08_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU6074589.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(44684..45412)
                     /locus_tag="VVR08_000635"
     CDS             complement(44684..45412)
                     /locus_tag="VVR08_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU6074590.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEIITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(45412..46152)
                     /gene="xerD"
                     /locus_tag="VVR08_000636"
     CDS             complement(45412..46152)
                     /gene="xerD"
                     /locus_tag="VVR08_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU6074591.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPMALLSELEPLMGRTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(46143..46604)
                     /locus_tag="VVR08_000637"
     CDS             complement(46143..46604)
                     /locus_tag="VVR08_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6074592.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(46601..47122)
                     /locus_tag="VVR08_000638"
     CDS             complement(46601..47122)
                     /locus_tag="VVR08_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU6074593.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     FPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(47098..48069)
                     /locus_tag="VVR08_000639"
     CDS             complement(47098..48069)
                     /locus_tag="VVR08_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU6074594.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNSKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(48066..48860)
                     /gene="racE"
                     /locus_tag="VVR08_000640"
     CDS             complement(48066..48860)
                     /gene="racE"
                     /locus_tag="VVR08_000640"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU6074595.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRKKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(49067..49315)
                     /locus_tag="VVR08_000641"
     CDS             complement(49067..49315)
                     /locus_tag="VVR08_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU6074596.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(49571..51196)
                     /gene="treC"
                     /locus_tag="VVR08_000642"
     CDS             complement(49571..51196)
                     /gene="treC"
                     /locus_tag="VVR08_000642"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU6074597.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(51374..53341)
                     /gene="treP"
                     /locus_tag="VVR08_000643"
     CDS             complement(51374..53341)
                     /gene="treP"
                     /locus_tag="VVR08_000643"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU6074598.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            53526..54236
                     /gene="treR"
                     /locus_tag="VVR08_000644"
     CDS             53526..54236
                     /gene="treR"
                     /locus_tag="VVR08_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU6074599.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        16253 a        12092 c         9766 g        16217 t
ORIGIN      
        1 aaaattgatt ttataatctt tcataaaaac ctctgagcaa aaatctactc aaaaattaga
       61 tgattaaaac atctaaaaaa caaaaggaca aaaacatctg tccctttgtt tactaaattt
      121 cagctaattt cttcgacata aataacacct acaatattag caatttcttc catcagtcga
      181 agatgttcaa atctacctga taattccaga gtaataaatg acgctatttt tttgtccgga
      241 acatcaaagt attcaattct gtcagaatta acatctccaa acgctgttct tgaatcggtc
      301 attctgatac cattttctgc acaataaacc aatacacgat tataggcttc tgtagattta
      361 actactatat acaattcaat cattttagaa cgattttgca gatatttttt tagtggttgg
      421 aacatggata tcacacccca aacagaaatg gctactaaaa gagctccctc ataaaaacct
      481 actccaatag ctaatccaat tcctgccgaa gcccaaatgc ctgctgcagt tgtcagacct
      541 gtaattttct ttttatctgt aataagaatc gttccagcgc ctagaaaacc cacacctgat
      601 ataacttgag ctcctaatcg tgtaggatct cctgtcccaa atttataaga tacgtattca
      661 ttcgtcatca taatcaaaca tgcagctaga caaacaatac tataagttcg gatgcctgca
      721 ggctgggatt tgctccctct ctctaaacca attatactac caatgactac tgataaaaca
      781 atcctgacaa ctatttcaat atttgataac ccaagactag tggctgtcat gattatttcc
      841 ttactttacg ccccggtctt tgtgtgaagt ataataccgt tccagaaata atcatcagaa
      901 caattgtata aacaaatacc agagcttgtg cattagatgt tgctgtttca tcacctgcag
      961 atcgaatcgt aatacctaat ggttgagcta ggggatggta aaggaataca gataagtcga
     1021 agtcagttaa taaagagtta aagtttaaag caataacaga gagaacaacc ggtaaaataa
     1081 atggaatgat aaccttcatc atagtataaa aaggtgaagc acccatactt cttgctgcat
     1141 cttccatctc atcatcaaca ctaaataaaa tagcacgtac cattctataa gaaaatggga
     1201 tttttacaac tatatatgca ataagtagaa ttaccaaact acctaccaaa atctgattca
     1261 agacaagaaa ttgtggctga ttaaaagtaa ataataaact tactgctaaa agtgtacttg
     1321 gtagtaacca aggaagtaga gcaccatatt caaataagaa atcaaaacga gatttatgtt
     1381 ttctgacaac acgagcaaat acaactgcga gaattgttgc tgttgtcgca gcaataatag
     1441 aataaataaa gctgaccaag aatggagaga atgccgcact attactaaag aataagcgat
     1501 aattttctaa agtaaagttt gataatgtta agttacctgt ttgaattgca actggatctg
     1561 taaatgagta taatactata aaaattagtg gaagcatgaa aactgtgaac aatccatatg
     1621 ctacaatgtg agcaatgata ttccaaggct tagacgcaat tttttgtttt ttaagaggtg
     1681 ctttagtctt agagatagaa atataatttc cacctttttc tatcttattc atgatagtaa
     1741 gcaaaattgt agttgcaata cctaaaataa ttgcaagtaa ggcagctaaa tcacgagaat
     1801 tccccatccc tgcaaatgta ataatcattg gatttatagt ttgaaattct ttaccaccaa
     1861 caatcatggg tgctgctact gcagataaac cactaagaaa aaccataata gtaagtgcaa
     1921 atagagttgg aattaaggtt ggtaacacta cttttcggaa aacagtaaat ggttttgctc
     1981 ccatatttcg agcagcctca atagtgtgat agtcaacgct tcgaattgta tttgttaaaa
     2041 acaatgtatg attagcagtt cctgaaaatg tcataatgaa taagactgca ccatacccaa
     2101 taaaccagtt agggtctaaa gaagggataa cattttgtaa aaattttgta atcaatccat
     2161 aaggaccata gacaaattta tatccagtcg ctaaaaccac tcctccataa attaaagagg
     2221 tcatataacc taattttaaa attttagcac ctttaatatc aaagtactct gtaaatagaa
     2281 cacaaagaat acctacgaca ttaactgtaa taatgagtga aaatgctaac ttaaaactgt
     2341 tcataatact ctgaagtgcc ctctgagatt ttagaacacg atgtaccgca tcaagggaaa
     2401 attctcctcc ttttacaaat acattcacta ctagatcaaa gtttggataa ataataaatg
     2461 ttactaagaa ccagattaac cctaaacgaa taagccaatc ttttaaattt aatttatgac
     2521 gcatactgca cctccttaaa attgcagaac gtctgatggt gtgataaata attccacact
     2581 ttctccgaca gatctaatag cagcctgact atcaatactt gttacattaa gaatctgact
     2641 ttcagaaact tttattgtat agtgaattgt aactccagaa aactcaacat caataattgt
     2701 cccttttaga ataaaatctt gttcagtttc acgattgaat cgaactttct ctaatcgaat
     2761 gtatcctttt ttatcctcta agaaaacgct tgtatttttc aataatactt cgtggactgt
     2821 ttcatcggtc aaaacattaa tatctccaat aaaatcacat acaaattcag tttgagaatt
     2881 atgataaatc tctactggtg taccgacctg ttcgatgtat ccattgttaa agactgcaat
     2941 tctatcagat aaagtcaagg cttcctcttg atcatgagta acatataaag tagtaatacc
     3001 taactctttt tgaagtcttt tcaactcttt tctcaaatct acacgtaatt ttgcgtcaag
     3061 gtttgacaat ggttcatcta gacaaagaat tttaggttca agaaccagag cacgagccaa
     3121 tgctaccctt tgttgttgac ccccagataa ttctgataca ttacgctgta actgttgatc
     3181 agagatctta atttttgctg ccactgctga tactttagct ttaataacat ctggagctac
     3241 cttcttaact tttaaaccaa atgcaatatt atcaaaaaca gtcatagttg gaaatagcgc
     3301 ataagattga aatacaatac caattccacg cttttcaggt tccaaatgag tgacatctgt
     3361 tccattaact tcaatacttc ctgatgatgg atttaaaaaa cctactaatg ctctcaaagt
     3421 agttgattta ccacatcctg aaggcccaag aaatgtaaag aattcccctt catgtatatc
     3481 taaattcaga ttatcaattg caacaaaatc accatattta atttgaatat tatcaaattt
     3541 aatcatctca ctaactccct ctattactaa accaaaagcc tctctttatt tcttccataa
     3601 atttagaaat aatagagaga cttggacata aaaaataact cttatttctt attgtacgta
     3661 ttctaattca gctttttcta cccattcatc caaatgcttt ccaacagctt cccagtcaat
     3721 attttgtggt ttcacttgat caacaaattt tttcgtatct tctggtagct ctttgagggc
     3781 atctttattg gcagggatag agccaaagtt tttactgtac tctacttgaa tttcagattg
     3841 accaaaccaa tcaataaatt ctttagccaa tgcttgcttc ttacttgtac tcaaaatcat
     3901 tgtttgctca gttacaaatg gaaccccaat ttcaggagac atcactttaa aaacaacatt
     3961 ttgttctttt tgaccaacta gagccccgga cccccagatc ataccgtatt ggatagcgtt
     4021 ttctttgtct aatactttaa caactgtgct ttcacctttt tgtagtgtat aggcatttgc
     4081 aaagtattct tttgcaactt cccagccctt ttccgatact cctaaatcac ctttttcatc
     4141 aagataacga actagaatac ttgcgtaaat ggcgcgtcca gtcccaccag ttaagccata
     4201 aatggaatat tgtcccttat atttactagc taactctgtc cagtcttttg gcatttcttt
     4261 tgcatcagga gttccaatca ataccaaggg ttgaacaatc acagggttat aataattatc
     4321 tttatctgat aaagattgat caattttatc taaccattta ggcttgtact gtactagtaa
     4381 tttttgatct ctaattttat ttgagtcaac agcaccaatt ccaaatacca tatctgcaac
     4441 tgcattattc ttctcagcaa taacacggtc tgctaattga gcgccagcaa tatcaaccat
     4501 ttttatatta aaaccagctt cttttgcttt agcagttaac caatcaccac gaccatttga
     4561 gactgagttc gaatagatta ctaattcttg acttttatca gctttttctt cagatgaaga
     4621 agcagtcgta gagtttgaac ctccagagca agcagcaagt gtagtaagag caactcccgt
     4681 tgtaagtaca gtagaccaaa ctttcatttt tttcatgata agttctcctt ttttattatt
     4741 ttatttaaat ttttcgtgat atggaacaaa ttgtctcata tcttcaaata cagtatagtc
     4801 aatacggttt acagtaataa ttggaatctt ctctaataaa atttcagtta attctgctct
     4861 gactttagta aactcttctt cctcctcttc ggttagagga atccgaagat acccaattga
     4921 aatatggaat tgatatctat catgattagg gaaacaaaca cctgcttttt ctgagacata
     4981 agtacgaatt tcttctaatc tctttgcaga agcttcatct gcaggttcaa ctagtatgtt
     5041 ttgttttccc atttcagtta tacgcatatg aatttcttca tccaacaatg gaaaaatttc
     5101 aagttgttta gcaaagtaat catgtatttc ctgtaaaggt gtatctagag gaagattact
     5161 gctccaaaac tccgtttcac gattttcatg gcacaacaat tcaattacag tcatgtgaat
     5221 agaattcctt ggagttaaag taaacttatc gataaatggt aattctctat aacgtgattg
     5281 aataatatca acaacttcca tcaaatcttg tttagtataa agatttgcta caactgtatt
     5341 cccagagaaa tgattaaatt ccccattctc tttgaactta atttttgtta agtttttcat
     5401 ataaagacct tcttttttat atttgacatc ggtgtcacca tgtttacatt atacaatgaa
     5461 accgtttcct ttgtcaagca cttgcaaaca tttttttaaa tttatctttc attaaatatg
     5521 catttcatta aaaggttaag taattttttc aaaatacagc actcatatag acagtatcat
     5581 caattatagc cattgggatt ttttgattgc caattccatg tatctctaca catgtcttca
     5641 atcgattttg ttgtcctcca atttaattcc ttatatgctt tgtctgcatt tgcataacaa
     5701 gttgcaacgt ctcctgaacg tcttggaact attttataag gaatagggat cttattaaca
     5761 ctttcaaatg tatttacaag ttgtaataca ctagtgcctt ctcccgagcc taggttatag
     5821 atataaacat ctgttttttc agatactttt tctaaagctt ttatatgtcc tattgctaaa
     5881 tctactacat ggatctttta tctcattttt ccctttttca aataagttat ctactctatg
     5941 atcagttatt tccatttcgt ttattaacat gacgcagtca cctagcatca tatactccaa
     6001 ctttttttct gaaagtttag caaatataaa agcaaatatt ggtaagcgat aatatagtat
     6061 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt
     6121 cctgattgat ttgtcctatt attatttcat tttactatac tctgttaatt catatgagtt
     6181 taaaccgatt tcatctttaa cctcgagtaa agcagtttca aatatttgtt taagagtttt
     6241 tgattcttta caattaaccg acaaactttc tgataaaata tatacaactt ctgagactga
     6301 ataacctatc tcctctttag aattatataa atctgtagct ccaccaataa tccaaaaata
     6361 ctgattttgt gaacctacaa tatcctcatt ttctacggaa cttccttgta tcgaacaaat
     6421 tttatttatc tttaccataa tacttcaacc cttttagtgt caaaagtaaa ccaattcctg
     6481 tcactgttaa gaatagttcc ataatcttgt tcgaaccagt ctttggtaat ttttgtttta
     6541 catctactat ttctttagat ttattaatat gattttcagt ttctctgcca tctccaacta
     6601 ttttatagtt tacttcttct atcttattat cttgtttatt gtcgatcttg tcattcattt
     6661 gtctattatc tttacttgag ttaaactctc cgttcttctg gttactatca attacattat
     6721 ttgaattaga ttgtttttcc tctttgtttt tttctttttc gtttttatca cttaaattat
     6781 ttgttacaat tttgtaaagc ccattctccg ttacaatatt gaaattacca tcgctatcac
     6841 gtataacagg ttctttccca tttgcattag atttgatgaa tgatatatac ttaccggata
     6901 aattataaaa ttggttattt aaaacggtta ttttaccctt tgaatcctca ataacaattc
     6961 cttctttacc cccgaatata ctattctctg agactactaa attatcacta actcgtaata
     7021 attcaatatt tggttgttct gtttccttag aattattatt aactacattt tttgttacag
     7081 taatatctga tacttttcct aaatattctg cactatcttt tgctactcta atagcctttg
     7141 ttttaggatc ggcaatatta aatatatttt cggcgataac cacctgttta tttaaatcta
     7201 ataggtcttt agtgttttta tagctataag catttactaa agctgctccg ttttctcgat
     7261 aatgtacact ctctccttta actttcttat caaagcgatt tcctttgatt aatacatcag
     7321 tgaatcctgt aaaacgtaca cctgcataca tcatgttatc aaaatgatta tttaaaattt
     7381 taatattaga ggggttctgt gtcgacaatg tttgatagtg tgtgccaatt gctgttacta
     7441 attccccaga tttatcactt ttgccaaaat aggaattttg aatagtcaca ttttcagatt
     7501 ttttcccatc atcattcaag gcataaggaa aaccttttct agttaatggt tcaatctgaa
     7561 tgctctcctt acttatgatt tgcccatcct tcatcgtttt gggtaaggct tgcccaagaa
     7621 aacgagaatt atcaactaat acatttttcg aacctgcaat ttgaatagca tgcccttgat
     7681 aactatcctt gaatgttaca ttttttatag ttacgttatt tgaattccca atagcaaatg
     7741 cacctgaaga atttataagt ggtagatttt ttgctttagt tccttcttca ttcaaagcac
     7801 cgttcatatc aatcgtacca ccagaataac taatatcttc tgttgggccc cattctactt
     7861 gcgcaccatc atccgtaaat aaacctgtca taaaaacaat ggaagggtga ttcttaatat
     7921 ttataccatt tagaattgta gctttctcat tcaattctaa gtgtgtataa ctttttaaaa
     7981 aaacaatttc ttttactaaa taagttcctt caggaaaata tacatttcct ccacctagcc
     8041 cttgagctgc agcatctatt gcatcttgaa ttgcttgtct atcatcatga atcccatcac
     8101 ctaccgcacc ataatctttt acacttaaag cagtatcttc aaattctttt ttgataattc
     8161 tgtcacttat aacatcttcc ttataactct tattttcatt agtagatgtt actgtagatt
     8221 caactgttct gttgtctaat tgtgaattgg aacgaatagt accattagag ctgatactat
     8281 taacacttaa cgaattatct aaaccattag tggttgaatt agaggcaatc atttcagcag
     8341 aacgattctg attaacagtt ggtgaattat ctaaatcatt agtaattgca ttagaagact
     8401 cttttgtagc catcggtgaa gaactagtaa caacttcatc cgataaaata ccttggcttc
     8461 ccaaaattga aattgccaat agtaccgagc aagtccccac ctttaattta cgaatactga
     8521 atacctcatt aggaacaaaa tatttcatca gaacctccaa tttttttact atttttaaca
     8581 attgattatt acttttctta aaatagatag aatgacaccg ctgtcattat ctttatcata
     8641 tattttccaa attgaattgt caaggaataa cacaagaaaa tattaaaatt tatactcttc
     8701 ggaaatctct tcaaactagg tcagtgccgc cttgacctaa gtctaggtta ctgacttggt
     8761 cagttctata gtagactgaa actataatag tacacctcta cttctaaaac attcttagaa
     8821 atcgatttga ctgtcccgat cgatttgtcc tattcttatt tcattttact atatctacaa
     8881 cctcaaagca gggttttgag ctatctatgg ccaacttcct agtttgctct ttagccttcc
     8941 attcaaaagt gatgctatct ttcttagctt gaatataaaa tatcccattt actatattta
     9001 aatttgttga tatgttgtaa attataaatg aaagaacaaa tatcttgtca tacaagcatt
     9061 cgccagggat atttacatga atatcgctca tatggcggat tgaaactaaa acactacaat
     9121 atatttctta aatagacctt ctataaaagc tagatttaac ctcgataaaa atagatgcag
     9181 tgcttctaaa atactggaat agggcatata ggtaatagta gacaagtgtt ttatagattg
     9241 tctcgcagga gatctaatga tgtatagcaa gcatcactaa acatatagaa tatttgcatc
     9301 attataatat caacatgtta taaattctat catgcaaaag aatgactaga acatgaaaga
     9361 caggcacaaa actttgaaca atattctgaa aacaaaaaaa agacgcgagt ttccacaatc
     9421 tcactcatgg aaactcacgt ctttcaaaaa atagggtgaa ttgaaaacta gaacaagaca
     9481 ctagattttc taaatgatgt ctagtaagga ttctaaatgc tacaccaaat tgctcacatc
     9541 ttatttcaaa ccacgggact cccacaagaa aggaaaatcc tataaaaatt ctctctctga
     9601 ggagaaagag gcctcaacta caggtgtaaa ctattatcaa ttgaaaacaa cagtttttac
     9661 actcaattag actttttagg gacaggatca ctttcgcttg actgtagttt gtcatttttt
     9721 tgataaagtt agcacttttt cagaaactgt tttgaaagtc tcaatgatat agtctacttc
     9781 ttcatcgctt aatttagtat gaagagggag ggtaatttca ttctcaaaga aggcataggc
     9841 cttaggatag ttcgtcatat caaatccaag attcttatag gctgtcaaga gaggaagcgg
     9901 tttgtagtga acattacttg caattcctgc tttagccaat tcttggatga tgaggttgcg
     9961 ttcttctagg tttgctcctt ctacacgggt gatgtagagg tggcgtgaag attcgacagt
    10021 ttcagtcttg tgtgccaaag gatggatgcg agaacctgca aaaccactat catagcggtc
    10081 cacaatgtcc ttacggcgtt gcaacaaact tggatagcgg tccaattgta ccaaaccaag
    10141 tgaagccatg atatcggtca tgttgcactt ataggctggt gtaacgatat cgtattccca
    10201 tgaccccaat tgcatcttgg caagagcatc cttagtttgc ccgtgaaggg aaaggatttg
    10261 gaattccttg tacatctctt cgtcatcaat cactggattg gctttccaag tcgcacttcc
    10321 accttctgcc gttgtaaagt tcttaacggc atggaatgag aaggaagtaa agtcagcgat
    10381 agaaccagaa ggttgtcctt tataagtaga tcccaaagcg tgggcactat cagagacaat
    10441 gacaatacgg ttaaaggcct tttgccactt gcttgaagcg gtaaagaagt cacgtttttt
    10501 ctccacgact tggaacaaac ggtcataatc gcaaacaatc cctgcgagct ctactgggat
    10561 aatcacctta gttttctcag tgatagcttg ctcaagcagg tcatagtcca tctcaaacgt
    10621 atctgcttgg atatccacca tgacaggggt tgctcccacg tgcgtaatga cactacatga
    10681 agccgtatag gtcatggctg gaacgatgac ttcatcacca ggtcccactt ccaaaacgcg
    10741 taaaatcaac tccagagcag ctgtcgcaga gttgagacaa acagtcttag gtgtctgtgt
    10801 gtaaagagac aagcggcgct ccagttcttt tgttttagga cctgttgtga tccaaccaga
    10861 acgcagggta tccgctactt cagcaatttc tgcttctgtg atatcaggcg gtgaaaatgg
    10921 aatattgtaa tttggcattg atttgctcct tttatctgta ctcattttct tatgactact
    10981 ttattttagt acctcaaaca cggtttgaaa catgattttg atgtccccaa agaaactaaa
    11041 ctctcggaga taggcgaggt tatagcgcat cttttcagga agaacatgct ccacataggc
    11101 ctgatcaact gacagacctt tctccgtcat ttgactgatg atggtgtcct catccttgta
    11161 gttgatgctg gctggagagg taattcctgc ttgcaagagc agggttgcca tcatttcagg
    11221 gctatactgc tctgtataac gtggcacttc aggtcgtgta ccgacaaagg acatctcacc
    11281 tttaaggaca ttgaccaact gaggcagttc atccaaacgg acacgtcgga tgaaatttcc
    11341 aaccttggta atacggctat cgttagcaga agtcaccaga cttccttttt tatccgcatc
    11401 cgtcaccatg gtacgaaact tccaaatctt gaaccgacgg ttgtactggg tcacacgctc
    11461 ttgcttgtaa atcactggcc ccttgctatc caacttgatc caaatgctca agatgagaaa
    11521 gatgggagag gtcagaacca gtaagatcaa ggccaaaacc cagtccaagc aacgcttgaa
    11581 aatcagcgaa cccttccttt tagagacaag ctggtagtaa gactcaacct cgcttgattt
    11641 catttccaca ggcaagtctt cccatttcag catgctgttc tcctttgttt ttattatact
    11701 atttgtcaac atttttcatt ataccacaaa atggaaaagg cggtgaaaga aatctgtaat
    11761 ttgaaggatt tccttctagt actcaatgaa aatcaaagta cagctttgag attgcagata
    11821 aagctgacat ggtttaaaga gattttcaaa gagtatcggc catggcccct gcctgcaaac
    11881 tatacatctt gtgataggtt cctcccagag tcaagagttc ctcatgggtt ccactctcga
    11941 taatgcgtcc cttatccaag acatagatgc agttggcgtc ttgaatagta gaaaggcggt
    12001 gagcgatagc aatagttgtt cggccctgtc tcatcttcgc cagagaagct tgaaccaagc
    12061 tttctgtttc agagtcaata ttggctgtcg cttcatccaa aatcaggatt ttaggctggc
    12121 tggcgactgt tctagcaaag gcaagaagct ggcgctgccc agtagagaag ctcgaaccac
    12181 gctcggaaac aggggagtcg tacccctgag gaagttcttg aataaaggaa tctgcatcca
    12241 caaaggctgc cgcagcctga acctgctcat cactgatttc ttggtacatg gcgatattgg
    12301 acttaatagt tccatgatag aggaagggtt cctgtaagac caaaccgatg ttttttctca
    12361 gctcttcttg actgaaatcc ctgatatcca catcatccaa gagaactctc cctgactgga
    12421 attcataaaa gcgcatgagg acattgataa tagacgattt ccctgaacct gtatgaccta
    12481 caaaggcaat ggtttcaccc ttattaacag agaaagaaat gtcatccaga atcggatgtt
    12541 taccgtcata cgagaaacac acatgttcaa aacggatatt gccttctttg actttagcct
    12601 gcccattttc ttgaaggggc tcataggtcc tctcatcgat taaggcaaag acacggcctg
    12661 cagaaaccat agacgtttgc agtgttgaaa agttttgcgt cacctcaatc aaggggtcaa
    12721 agaggcggtt gatgtactgg ataaaagcat acatggtccc ggccgttatc ccgatagaaa
    12781 gaccacggta gccaaaatag gccaccaaga cagcataacc tagaagtttc aacaaactca
    12841 tggcaggtct caaaaagagg gcatccaagg ctacagaacg gttggcatag accaagtgct
    12901 cttggttgat ttcatcaaat tctgcctgca ggcgcttctc ttgattaaag gcctggatta
    12961 ttctgattcc ctcgatgttt tcagccagct tgctattgat atctgacaag agacttctgg
    13021 ttttctcaat gattttcact gattttttcc gatagagatt gaccaaaagg aaaatcaagg
    13081 ggagaaagag caagactaat gctgtcaaac gaaaatccaa taccaacatg gtataaaggg
    13141 ttgtcagaaa gatgaaaact gctgagataa agctagataa aatccccgaa aacatatcac
    13201 taatcgtctc ggtatcgttg gtcaaacgag aaacgataga acctgctggc gtcttgtcaa
    13261 agtaagacat gcccagtttc tccatattgg caaaggcatc ccgacgaata tccctaacaa
    13321 tactgtaaga cacgcgcgca aagagaagat tgccgacata ctgaactaca gtttgtagga
    13381 tgtagagacc atagtagacc agcaaaacgg taacggctag ttggttgaga ttgctgagat
    13441 actggtcgat aaagtgggaa gccacgaggg gtatgacact tttaatgacc gtcgtcgcta
    13501 ggagaaaact gagtgccaaa aaggtcagga gtccataagg cttgagataa gacatcaagc
    13561 gcttcaatac agcccattgt tcttgtttat tctgcatctt cttctccttt catttccaac
    13621 tgctgagact ggtaggtttg ggcataccag ccatccaaag ctagcaagtc ttcgtgcctg
    13681 cctcgttcga taatttgacc attttgcagg actaaaatca aatctgcatg gacaacagca
    13741 ctcaggcgat gggcagtgat aatggttgtt ttgtcctttc gcgtctcctt gaggttgtcg
    13801 ataatcgcat actctgtctt ggcatctacg gcggataagg aatcatccaa aatcaagata
    13861 tcaggttcta aaatcatagc ccgactcata gccaaccgtt gcttttgacc accagaaaga
    13921 ctgactcctt tttcaccaat cagcgtatca aatccttgag gcatgtctac aatatcttgg
    13981 taaactcggg ctagcttagt agcttccacg accgctgaaa ggggcaagtt aggattgcca
    14041 aagcggatat tgtctaggat tgaagtcgca aagagaaact ggtcctgagg aacatagccc
    14101 atgagactgc gaaggtctgt cagacgatag tcccgaatat cgtgaccgtt tagataaata
    14161 gtacccttat ccacatcgta ttcacgcaag aggagcttga ttaaggacgt tttcccagag
    14221 cctgtctgcc caaccaagcc cagtgtttgc ccttttgcca aactaaagtg aatatccgtc
    14281 agtgtttcct cattttcaaa agcaaagctg tcaatggcat actccaaacg cccattttca
    14341 ataccatcca gaggaaactc agggtcttgt acaggagatt cctgagacaa aagattttca
    14401 atccgctggt aagaaacctt ccctcgctga gtagtattaa agaggaagcc gatggccata
    14461 agaggccaga ccagcatatc caaatagctg ataaaggtga ctagattccc aactgtaatc
    14521 tgcccttcct gaaccatcaa ggagccaacc aaaagcgtta aaacatagga cgaaccaaca
    14581 aacaagagaa ccatagggtc aaagagacta tcatatttca tggtttgcag gttcttttgg
    14641 aaggttaatt cattgactgc ctgaaaagac ttcaactcgt ctgcctgata accgaaagac
    14701 ttggtcactt tgatacctga tacggactcc tgtaccttgt tattgagttc agaaaaagca
    14761 gcttgggatt cgccaaaggc cttatgagtc tttctcccta ggcgactagt cgtataggcc
    14821 atgaaaggta gggggagaat ggcaacaaga gtcatctgcc atgagatgct aaagagcatg
    14881 gtcaacaaag tcaccagagc cgtgatagag gcatccaccg cagacatgac accgccacct
    14941 gctaaacgag tcaaggcatt gatatcattg gttgcgtgtg ccatcagatc acccgtccga
    15001 taggtttgat aaaaggctga cgacattttt gtgaaatgct taaacaagcg agaccgcatg
    15061 atctgtccca agcaataaga ggtcccaagg atatacatac gccacacata gcgcaaatag
    15121 tacataccaa atgctgcaag tagcaagtaa aataggctaa gaaggaggtc ctgctgggtt
    15181 aattgccccg atgtgatggc atcaatgacc cgccccataa ccataggagg aatgagattg
    15241 aggacggaaa ccaagatcag ggccacaatt ccgactagat aacggcgttt ttctaacttg
    15301 aaaaaccacc aaagtttttg aataatggac ataaaatccc tttctgattg caaatggaaa
    15361 cctgaggcca atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggctgct
    15421 caaagcactg ctttgaggtt gtagatagaa ctgacgaagt cagtaaccta catacggcaa
    15481 ggcgacgttg acgcggtttg aagagatttt cgaagagtac aagaccccag gtttttctta
    15541 ttcataagtt acgactgtaa cagcaccctt gtcatattca gcaataaaga tattggctac
    15601 attgtcatgc ccttgtttac tgaggttatc aagcaaccac tcttcgctac gaccaatcga
    15661 ttccaagaca tctacttgaa tcacaccgtc agtcacaact ggatacttag gattttcatc
    15721 tcccatttgc acaacgatga gttgcccatt ttgctcttgc acagctcgtt tgacttgctt
    15781 catctggaaa atcccttggc tacgaagttt gagggataca tccgatgcag acaaaccaac
    15841 tgaacgacag gcttctgggt caatattccc atttttgata aggagagttg gcttaccatc
    15901 aatcaaacgt ttcacaaagt gaacattgtt gttgagctat ttgagagtca agaccagttt
    15961 gattaaaatt tcgatataat taagtgtcat ttgttcacat ccaccagttc aattgcgtct
    16021 gtcttataca attcgacttt ctctaacagg tacttgtctg gctcacttcc gtttagggca
    16081 cgataatagc gatctcccac cttgataagt gcgccatctg tgtttgtgga agtattaaca
    16141 tagacttctg acttgtctac tcccaaatct ttggaaacaa cctcgatgaa atgaagtgaa
    16201 gtttgaaatt tattgttaga aacttgattg ttttgataag tcgtgatgct gaccaaaagc
    16261 agagctaaat aaggccagat ctgaaatcat gaccaactca cgaaattcgc ttcccttttt
    16321 attatggtat gccttgaaag caaaaaaaac tgtcacagct aatagaacaa tcccaaagcc
    16381 aaccatgata ccattttgct gaccgatttg gctgagtaca tagtcataag agtagaattt
    16441 catgtatttt cactcccttt cataaaatca ttcttaatta taaacgaaag agagtaattt
    16501 ttcaaaccat acgttgggga aatagatctt tttttggtat aataaaatct atactctgaa
    16561 tgaaaaaggt aactttatga aacttatctc atggaatatt gattccctaa acgctgccct
    16621 aactagtgac tcagctcgtg ccaaattgtc ccaagaagtc ctacaaacct tggtcgctga
    16681 aaatgctgat atcattgcta tccaagaaac caagctttct gccaaaggac ctacaaagaa
    16741 acacgtggaa attttagaag aactcttccc aggctacgaa aacacgtggc gctcttccca
    16801 agagcctgcc cgtaaaggct atgctggaac catgttcctt tataagaaag aacttacacc
    16861 tactatcagc ttcccagaaa tcggtgcccc ttctaccatg gacttggaag gtcgtatcat
    16921 cactctagaa tttgatgcat ttttcgtaac ccaagtttac actccaaacg ctggtgacgg
    16981 tctcaaacgc ttggaagaac gccaagtctg ggatgccaaa tatgctgagt atttggctga
    17041 actagacaaa gaaaaaccag tccttgcgac cggtgactac aacgtagccc acaatgaaat
    17101 cgaccttgca aatcctgcta gcaaccgccg ttcacctgga tttactgacg aggaacgtgc
    17161 tggatttacc aaccttttgg caactggatt tacagacacc ttccgccatg ttcatggcga
    17221 tgttcctgaa cgctacactt ggtgggcaca acgcagcaaa acttctaaaa tcaacaatac
    17281 aggctggaga atcgactact ggctcacaag taaccgtatc gctgacaagg tcactaaatc
    17341 tgatatgatt gactcaggtg ctcgccaaga ccatacaccg attgtcttgg aaattgactt
    17401 gtaaggattt tctatatgga ctacaatgcg gtcattcccg agttgcttgt atcgaatatc
    17461 gaacagtccc ggtccttcta ctgtggttta ctgggtttta ggattgaata ccaacgtcca
    17521 gaagaaaact ttctctttct cttgaagagt gtcaactaat gttagaggag ggaacaaagg
    17581 atcaactagc tgaactgacc tatccctttg gtcgtggagt caatctctcc tttggcataa
    17641 aggatgtttc aaaactctat taaagagtga tgaaggcaaa ctatcctatt tatcgtccct
    17701 tgaccaagag aaagtttcgt gtcagtgatc actatatcta tcctcatgaa tttgcagttt
    17761 tggatccaaa tggctatttt ttaagattta gcgagtagaa taataaaaat tgggaaaagt
    17821 ctttaaagtt agaaaaaggc atattgtcag gtgtctaaaa acttgatagt atgcctttta
    17881 tgatggaaaa atcttctaat actcttcgaa aatctcttca agccacatca acgtcgcctt
    17941 accgtaggta tatgatactg actctgtcaa ttctatccac aacctcaaaa cagtgatttg
    18001 aggttgtgga tagcttccta gtttgctctt tgattttcat ttagtataaa tgttagctta
    18061 caatggagtt tttgttcacc ctctcttctg tttgttcgtt ttttaaacca aaacactaac
    18121 aaaatagttg gtttctaaag ttatttagtg taaaataaaa acattggctc aagcctattt
    18181 aaaattgaat atcgttttac ttgtttatgt cgtgaattgg cacgacgttt ctacaaggtg
    18241 ccggaacacc taacaataag taagtcagca gtgagatatg gccgtttttg ccatgtctat
    18301 ttaggggact tacttagaga ttaagtaggt cttttttgaa tatttttaat atttccctta
    18361 attagtgcgg acgggaggtg aaattatcct gtgaataatt tcaggaatcc agggaatttc
    18421 atccctaatt tttgagcccc tagctctttc atttctaggc ttaggctaaa atagttcccc
    18481 gaactatttt actctcaaaa atcccgtcat agacaataac aagattattg tctatgatac
    18541 cactacatcg ggaaatattt gataagactc gcttcgctcg taatagtttt atcaaatata
    18601 tagtattagc aaaagggatc actatagaaa catttaaaca acaagtaaat taacttttag
    18661 actttaggag gtcttatgaa attattagaa gagcgcatcc tcaaggatgg gcatatcttg
    18721 ggcgataaca tcctcaaggt agattccttt ttaacccacc aagttgactt tagcttgatg
    18781 cgagagattg gtaaggtttt tgcggaaaaa tttgctgcta ctggcattac caaggtcgta
    18841 accattgaag cgtcgggtat tgccccagcc gtttttacag ctgaagcctt aaacgttccc
    18901 atgattttcg ccaaaaaagc taagaacatc accatgaacg aaggcatctt aactgctcaa
    18961 gtctactcct ttaccaagca ggtgaccagc accgtttcta tcgctggaaa attcctctca
    19021 ccagaggaca aggttttgat tatcgacgat ttccttgcta atggccaagc tgctaaaggc
    19081 ttgattcaaa tcatcgaaca ggccggtgct acagtccaag ctatcggtat cgtgattgag
    19141 aaatccttcc aagatggtcg tgatttgctt gaaaaagcag gctaccctgt cctatcactt
    19201 gctcgcttgg atcgttttga aaatggtcag gtcgtattta aggaggcaga tctctaatgc
    19261 aaactcaaga aaaacactcg caagcagccg ttctgggctt gcagcactta ctagccatgt
    19321 actcaggatc tatcctggtt cccatcatga ttgcgacagc ccttggctat tcagctgagc
    19381 agttgaccta cctgatttct acagatatct tcatgtgtgg ggtggcaacc ttcctccaac
    19441 tccaactcaa caaatacttt gggattggac tcccagtcgt tcttggagtt gcattccagt
    19501 cggtcgctcc cttgattatg attgggcaaa gccatggtag tggcgctatg tttggtgccc
    19561 ttatcgcatc tgggatttac gtggttcttg tttcaggcat cttctcaaaa gtagccaatc
    19621 tcttcccatc tatcgtaaca ggatctgtta ttaccacgat tggtttaacc ttgatccctg
    19681 tcgctattgg aaatatggga aataacgttc cagagccaac tggtcaaagt ctcttgcttg
    19741 cagctattac tgttctgatt atcctcttga tcaacatctt taccaaagga tttatcaagt
    19801 ctatctctat tttgattggt ctggttgttg gaactgccat tgctgctact atgggcttgg
    19861 tggacttctc tcctgttgcg gtagctccac ttgtccatgt cccaattcca ctctactttg
    19921 ggatgccaac ctttgaaatc tcatctattg tcatgatgtg tatcatcgca acggtgtcta
    19981 tggttgagtc aactggtgtt tatctagcct tgtctgatat cacaaaagat ccaatcgaca
    20041 gcacgcgcct tcgcaacggt taccgcgcag aaggtttggc cgtacttctc ggaggaatct
    20101 ttaacacctt cccttacacc ggattttcac aaaacgttgg tttggttaaa ttgtcaggca
    20161 tcaaaaaacg cctgccaatc tactacgcag ctggtttcct ggttctcctt ggactgcttc
    20221 ctaagtttgg tgcccttgcc caaatcattc caagctccgt cctcggcggt gccatgctgg
    20281 tgatgtttgg ttttgtatct attcaaggga tgcaaatcct agcccgagtt gactttgcta
    20341 acaatgaaca caacttcctt atcgcagctg tttcaatcgc tgcaggtgtc ggtctcaaca
    20401 acagtaatct ctttgtcagc atgccgacag ccttccaaat gttcttctca aacggaatcg
    20461 tcgtagccag cctactcgcc attgtcctca atgccgtatt aaatcataaa aagaaataag
    20521 aaaaagaggt gcgagcctct tttttgttta tcacaaattg attataaata caatcaatcc
    20581 caattcccat ctaattgaat tggacctatt tcaaattctt taaaatatta tgttccaaat
    20641 cgttaatatt atataagaat ggtaaaatat caaatgtttc tcgtaaatta ttcttagcct
    20701 tataccaacc ttgtccatca gtaatccaca taaactcaac attaggaata gctttaattt
    20761 cttcagcaat cattttgtaa gatctagccg tctcatttaa ttttgaacca cttcctgaat
    20821 aaaaattaac ctcaatcaga taaagcactt gttcattttt tatgacaaaa tcaaaacgtt
    20881 tcacagtatt cccatcattc gtaatagcag ataaatcgac agaaaaaatt tcctctattt
    20941 cattttgttc aatctcttta aataaattct ctcctaaaat atacccttca gcttcaagat
    21001 agctttgaac aatattttcc atcgcatctc cagtccgatt tttgcgccca ttagtatcca
    21061 taccaacctc aacacctgta acgtagtcaa ctaaatttga tactaaatga ttttgcaata
    21121 aatcaaatat acctgatttt tccaaaaaca tagtatattc ttcaatacta tagtttcgtt
    21181 tactaaaatc aaaatagaaa tcttttatcg gatccttaac aataatcgta tctctcaaac
    21241 gtttagcaat aagtagaggc acaactttca aaatttctgg ataattttga tataagtcta
    21301 aaaaatcctc ttgtatattt ttactaccaa taagactatt cataatattt agagcaactt
    21361 ttatactaga tacattttta taaaccttag gaaaatctgt ataataagtc cagtcagcta
    21421 ctgtgtcggt catcgttgac aaccactcat caaaatttct agtttgtttc attttctgcc
    21481 tccaacctct tccttgcaat ttttaaatat tctttttcag catcgatacc tataaatctt
    21541 ctacctaacc gcttcgcaac aacacccgta gtgccactac caacaaatgg gtctagaata
    21601 tagtcaccct ctttagtaga ggctaaaata atgcgttcta acaaatactc tggtttttga
    21661 gttggatgtt tcccagccca tttttcaact ttctttgtta aagaaccggt ccagacatct
    21721 ttcatttgtt ttccatcatt caattctttc attaaatcat aattgtagta atgacgagct
    21781 tttttatcat tttttctggc ccataaaatg gtttcagtag aatgggtaaa ataacgacaa
    21841 gataaattgg gggcagggtt tgttttctgc caagtaatat tattcagaat tttaaaacct
    21901 tcttgttcta atgccattcc aactgagtat atgttgtgca aactacctga aatccatacc
    21961 gtcccattag gcttcagaac ttcttttgct aggcgaatcc atttacgatt aaactcatgt
    22021 ttttcttcga atgaagaaat tttatcccaa tctcctttat caacagaaac aacttgtccc
    22081 ccagaattag atattccacc attacttaaa aaataaggtg gatcagcaaa aatcatatcc
    22141 atactttctg gtttcatttt tgataagaac ttgaacgtat ctgaatgaac aagaatcatc
    22201 ttatttttat tgtagtatgg ttttgtcata agaacacctc catacttata ttcgttattt
    22261 ttcataattt gtgactataa tttcagaaat ttttcctcga cttgaagatt ttgctccatt
    22321 agttcgggta gcttcaacat aatgtatatt aaaatcctta tacaactcct ctactaaagc
    22381 actagaagaa tttgataaca taacataagc tcctgtatca ctcaatctct taaaggcatc
    22441 tcttaatctt acttgatctg caaaagagaa tccctcatga gtataagacg taaatgcact
    22501 cgtctcagac aatggaatat atggagggtc aaaatacaca aaatctcctg ttcgaacatc
    22561 tacaattgcc ttttcaaaat ctcccacttt aatttctagt tgattgttat ttatataaac
    22621 tgaaatagca gatatcaatt cctcatcaac aattttagga ttcttataac gtccatatgg
    22681 aacattaaat tgattcttag aattcacacg atatagacca ttaaagttca ctctcaacat
    22741 atatagaata cgtgcagctc tttgtacttc ggacatcata tctattcttt catcacgatc
    22801 tgcagaacgt aaatctaaat aatattcttt tgaattatat tcctgatgaa ctttcaaaat
    22861 ttcaatcaat tcttgaggat tgtccttaat ttgttgatag caatttatta gttcagcgtt
    22921 aaaatcatta ataactgcat ctttaggagc caaatcaaaa aataaagctc cacctccaac
    22981 aaaaggttcg aaatacctgt tataggtttt aggcattaat tctctaataa caggcaataa
    23041 ttgtctttta ccacctgtcc atttcgtgaa cggttgtaaa gtaactttct ttatttcttt
    23101 tatcttcatg cttttaatta taccatagaa attaaaacac aactcttgta ttttctacca
    23161 cattactaaa ttttctattt tagaattaaa tcatatcaat atcaaaaaat gagtaaggca
    23221 aatcttataa attccaaaat tcacctcact ctattaaatt actctttata tccttacctg
    23281 tctttcttct gaccgctggc ctgtgacaaa catggtaaag gttgctttac agacatttct
    23341 gccctcttga ttggtgatat ccacatccat cacacaggtt gtacgacctt gatggacaca
    23401 ttctccttta atggtcaata catcgtcgag ttttcctgcc ttaaggtagt tgatagagga
    23461 ttggagtgtc accccatcaa gtcccagcga gataaccacc aaaccactga tttggtcaca
    23521 tagcgtgaat agatagccac catgggcatt gccatagtag ttgagcgacg agttcactac
    23581 tttggtcgtc accacaacgt gaccatctct cattttttca atttcgtaat tttcaaaggc
    23641 agatatagcg tcaaaatgaa agtctttcat cgtttcctcc tgatatttca aacgacacta
    23701 tgatactact ttttatagga ctgtgcaagg agaaagctcc tagtctagta aaattccgac
    23761 ctgttccaca aagcgcataa aggctgtctg accttgttct gtctgcttgt agactcctgc
    23821 atcctcaagt acacgcacaa agatagcacc cacagagtcc ttgacgattg caagggcttt
    23881 ttctttatcc gttaggtctg gatgttggga tttgagttgg tctgcccact cctgatgata
    23941 atcggcaact gtaacagctt ctcctacaag atagctagcg acttgctcca cttcttcttt
    24001 cagacgtggt ggcaagattg ccaagcccat gacctcaatc aagccgatat tttccttctt
    24061 gatatgttgg acatccttgt ggggatgata gatgccatca ggatgctctg ctgaagtctg
    24121 attgtctcgc aagaccaagt ccaactcaaa ctgtccatca cgcttacgcg ctattggtgt
    24181 gatggtgtga tgcggtgtcc cgtctgtctc tgctaaaatc tgcacactag aatctgaata
    24241 ctgacgccat tcctggaaaa tcttatcagc taagttaatc aaatcctctt tggaatccga
    24301 agtcaagcgt aggacagaca ttggccactt gataattcca gccttgacct gctcaaaacc
    24361 agcaaatcgg aaggtctttt gcaagggagc caattccata ggaaatacgt gacggcctcc
    24421 ctgataatga tcatgagtta gaatagagcc ccccacaatc ggcaggtcgg cattagatcc
    24481 agcaaaatat cctggaaact gctctacgat agccaacaga cgttcaaaac tctgacgact
    24541 aatggccatg ggacgatgct ggccatctaa aaagatacaa tgctcattaa agtaagcata
    24601 gggcgaatac tggaaccccc attcctgacc aaccatttca aaacggataa tccggtggtt
    24661 gctgcgagct gggtggttga cccgaccatg gtaaccctca ttctctaaac aaagttgaca
    24721 ctgaggataa ttactagctt gcaccaactt ggctaccgca atctctttcg gatccttttc
    24781 aggcttagag agattgatgg taatttcaag ttctccataa tcagatggaa cacgataagc
    24841 gatattttta gcaatggcct tgagtttgat gtagtcattt ttccgactga gttgataaaa
    24901 atcctctatc gcttgctcag gagagtaggc ataagcttcc cagaagtcac gattgacctg
    24961 actcggacaa ggagtcacca agtccatcaa ttcagtacca aggatttcac gcgcagtctg
    25021 actatcctca atcgtctcta atcgaacggc ttcctcaact agctggtcct tgaggtcaat
    25081 caatttatcc agattggtct caacttccaa aacaccttct cccactcgtg ccaaaacacg
    25141 attggtcagg tagattcgat ccatttcctc aaatgaactt tcagaaatga catgtgttac
    25201 aaatttatct actaaggtca ctatagagcc tccttttgac tagtcaagga cgcgagtgcc
    25261 acctgcaact tcagcgatat agaagcttgg agcgtatcca actacttcct cgtagtgttt
    25321 gcctacagct tccttaaagg cctcaacagt atctttttga accaaggcaa tggcacagcc
    25381 accaaaacca gcccctgtca tacgagcacc gagaactcct tcttgtgccc aagctgtgtg
    25441 aacaagagta tccaattcca aaccagttac ttcataatca cgctccagag aaacgtgtga
    25501 cgcattcatc aaacgaccaa atgtttccaa atcacctgct tgaagggctg cttgagcttt
    25561 aagggtacgt tggttttcaa gcacagcatg gcgagcacgt ttcaaacgat tttcatcttt
    25621 aatcagatag ctatattggt caacggccca ctcgtccaat tcacccaggg tctgaatatc
    25681 caaggcaact tgcaattctt ccactgcttt ttcacactca gcacgacgtt cattgtattt
    25741 agagtccgcc aattcacggc gtttgttggt gttcatgata acaacgacat tgtccttcaa
    25801 atcaagtggc accaagtcgt attctaaagt attggtatct aagtaaatag cacgttggtc
    25861 agcccccata ccaatagcaa attggtccat gataccagag ttgactccga taaagttgtt
    25921 ttctgtttgt tttccgattt taaccaaatc caaacggtct agttttaaat caaagagatg
    25981 ctctgccacg actcctgtca agagctccaa ggatgctgaa gaagacaagc cagaaccatt
    26041 tgggatattc ccataaacat aaaaatcaaa acctttgtca atcacatgcc cagctttttg
    26101 caagaaatga agaacccctt ttggatagtt ggtccagttg tgctcttttt caaacttgag
    26161 gtcagcgaga ggcacttcga ttatgccctt gtcctcaaag ttagctgagt agaaacgcaa
    26221 gacttggtcg tcacgcttac gaactgcacc gtaagttccc aaggaaatag cagcaggaaa
    26281 aacgtgccca ccgttgtagt ctgtgtgttc accaatcaaa ttgatacgac ctggtgaaaa
    26341 gaaagtttgg tctgcttctt gaccaaaaac agcaagaaag tctttgcgaa gagtttcagc
    26401 agtaagatgt tgtgtcatat gatttctcct ttgactgtcc gttaagccac cttaacgtgt
    26461 aatcgttttc ttctattgta tccaagggat ttctcaaggt caatcctttt tactaaaatt
    26521 ttagtaaaat atcagtaaaa agaagaaaaa catgatatac taacctaatc aaggaggatt
    26581 tatggctacc ttaaaagaca ttgcacagct agcctctgtc tctatcgcga ccgtatcccg
    26641 cgtcctcaat cgcgaccaga gcctatctgt tacagaagaa accagacacc gtattttaac
    26701 cgttgctgaa gaactgggct acaccaagca cctcaagaca ggcgagtccc acaaacccaa
    26761 gcaaaagatt gccattatcc aatgggtcag cgaacaaggg gagctggacg acctctacta
    26821 ctaccagatt cgcctaggaa tagaaaaaag agcccaagag ttggactatg atatcttgcg
    26881 ctattttaat gaccatcctt ttaccttaag cgaggaagtg attgggattc tctgcatcgg
    26941 aaaatttagc cgagctcaga tttctgcctt tgaagaatac caaaaacccc tggtctttct
    27001 agacagtgat acactttccc tggggcatac ttgtattatt acggactttt acactgccat
    27061 aaaacaggtt gtcgattatt tcctcagcca aggaatggac cgtatcggga ttctaacagg
    27121 ccttgaagaa acaacagacc aagaagaaat cattgaggat aagcggctgg aaaatttcag
    27181 aaactacagt caagcaaaag gaatctatca tgatgaactg atctttcaag gaaactttac
    27241 tgcccagtct ggctatgact tgatgaagga agccattcag agcttgggag accaacttcc
    27301 gccagcattt ttcgcagcca gcgatagttt agctatcggt gccctccgtg ccctccaaga
    27361 agctagaatc aacctgccag atcgcgtcag cctcatttcc tttaacgaca ctagtctgac
    27421 caaacaggtc tatcctcccc tctctagtat tacagtttat actgaagaaa tgggccgagc
    27481 aggtatggat attcttaaca aggaagtcct ccacggtcgg aaaatcccta gcctgaccat
    27541 gctgggaacc agactgacat taagagaaag taccctaaat caagaatagg ataacataaa
    27601 aaacgaatag gagttttaga actcctattc gttttttatt cgattacaat catagactta
    27661 atggtcttac gttcatccat atctttgtag gcttggtcga tatcttccag tttataactt
    27721 gaagtaaaga cgcgacctgg attgatatca ccatcaagga cggcttttag taaaaattgc
    27781 ttatcgtatg ttgtagcaga agctgcccca cctgctacag agatattttg cataaatgtc
    27841 gaaccaagag cacgattatt atagtgtggg actcctacaa agcccatacg ccctccatta
    27901 tgaagaacac ctagcgcctg ttctatagca gcctccgtac caacacattc aagtgctgca
    27961 tctgctcctc caccgaggat ttcacgcacc tttgtaattc cttcttgacc acgttctgca
    28021 acaacagctg tcgcacctga ctccatagcc atcttttgac ggtcttcatg acggctcata
    28081 aggataattt gtgatgctcc acgcatctta gccgcgatga cagcacattg accaacagcc
    28141 ccatcaccaa taacaacaac cttgtcccct ttttgaacat ttgcaacacg cgccccgcat
    28201 gatagcctgt cggcatgaca tctgcaagag tcaaaaggga cttgagcatc ccttctgtat
    28261 agtcagaagg ttgaccaggg attttaacca gcgcccagtt tgcatagtgg aagcgaatat
    28321 attctgcctg aaaatcaccc cccaaattat tgccaatatg attgtcgcaa gaaccgtcaa
    28381 atccagcaag acaggcatca cactcaccac atccatgtgt aaaagggaca atcacaaaat
    28441 cacctggttt caccgtcgta atggcttccc cagcttcttc aacaatccca atcgcttcgt
    28501 gtccactatt tttgtgtcca gctttcgttt ctggattacg gtacctccat aaatctgaac
    28561 cacaaacgca cgaacgaacc acacgaataa tcacatcatc cgcttctatt atttgcggac
    28621 gttcaatgct aacaagtcca acctgacctg cctttgtata tactgctgat ttcatttaaa
    28681 attttccttc cttataaagt ttaattttga gatttaaacg atttaaagct gtctgtagct
    28741 gagacaagcg ctcctctaat ttttgctttt cctcttctaa aataccaagc ctctcctctc
    28801 tcgtttcatc tcccttttgg tagagcgaca tatagtcaac taaactatct acagagacac
    28861 ccgccgaacg aaaacactta ataaattcca gcgcttcgat atcctgatct tgaaaatcac
    28921 gaatcccagt agcagtacga gtaatcggtg gcacaagacc aacccgttca taataccgaa
    28981 tcgtatccgc tgaaattccc aacaaatcac tggcagattt aatattcaca cgctaacctc
    29041 ctctcatttc attcactgaa ttcacgctat tctaactcac ttatcttatt atataacttt
    29101 gagttgactc caagtcaagc attttgtatc taatcgaaaa atttttatca ttaacaatca
    29161 tatatctgga gtttatacaa tgctcttctc ttaccaattt ttgaaatatt taaataataa
    29221 agaaattact ctattccaaa taagatagta cccaagtatt tttcactttt ttctaatgtt
    29281 gatgctcata actccgttcc aagtcacaca cctttcgctt atgggtttgg tgagtttcta
    29341 ggtcagcatc aatttcaatg gtaatatttt gaaaaccaca atcttttagg aaaattcgaa
    29401 tagactcttt acaagtttcc atatgttcca tttcttttag acaaacatgg acaatggcat
    29461 ttttttccaa agcatccata gtccagagat taagctgatt aaggctggcc acattgtcca
    29521 atcgttccag gccactcttt acttgcttga tatcaagacc ttctggcaca gcatccaaga
    29581 aaatcttgag tgtagaccaa aaacgtgaaa gggcttttga aagaataaag aaagaaatga
    29641 caagggacaa aagaggatct aggatatacc agtccgtaaa tcgaagaaca atcgccatca
    29701 ggataacagc tacccaccct agcgtatctt ccagaaaatg cagactcaga atagactcat
    29761 tctttgtctt tcccttacca accaccagac tcgctaacag attgatagta atcgcaataa
    29821 ttcctaacca gagaatcccc tcatcattga ctggttgcgg atgcaaaatc ttcgtgacat
    29881 tttccaaaat gactagaaca gagcctgtta cgagaatcac agctgttacc aaggctccta
    29941 gcaggctaaa ccgcttatag cccaaggtgt actgattgtc ttcttcacga ttggagattg
    30001 tttctagaaa agctgatatt ccaattgcaa tcacatctcc caagtcatgc acagagtcag
    30061 caagaacagc gctagaacca aatactccac ctgcaataaa ctcaacaatg gcataagtca
    30121 aatttaagaa aaaagccacc caaacagcat attttgcctt catatttctc attcctttgt
    30181 tataataggt ttatgaacac cttgttcatt atcattatcc actaaaactc aaagaaagga
    30241 tagaagcaaa acgtcagctt tattcagttc tgaacaattt gccttaagtg tccatatgac
    30301 taacattgac cgccgtatca gcaaaaccaa aaaagccatc tatcaagctt ttatacaact
    30361 tttgaatgct aagggctacg aggccactac tgttcaggat atcattgatc tcgcagatgt
    30421 gggaagatcc accttttact gtcactatga aagtaaggag cttcttctgg accagctctg
    30481 ccgctacctc ttccatcatc tttttgaaag agagcaagcc atttcaaccg aggactacct
    30541 cgcccacctc tttctccatt ttcataaaaa ccaagaccat atcaccagtc tgctattttc
    30601 caaaaatgac tacttcctcc gtcaactcca taaagagcta gaacaccatg tctattccgt
    30661 gctagctgat aatttaaaag aagcccaccc taatatgcct acttcttacc tccaacactt
    30721 ggtcgtgtcc aactttatcg agacattgac ctggtggctc aaaaaaggtc aagatttcac
    30781 agaccaggaa gttgtccaat tttatctaga ccttctcatt cctaaaaatt gaatatagag
    30841 taaagctcag ttgtcttatt tctaggttac tgagtttttt atcttttcaa caacaaaaga
    30901 ggacccgccg atcctctttt tcatactata aatccttgat tatcaactat atctgtttta
    30961 atcgaaatct caaaacagca ctttcaaaca tcttttccta gttaggtaaa tcagtattct
    31021 gcttagctgc cttgctccat tgataccaac caactagact gttaatgaga taaattagat
    31081 atttcccttg aatttgcagg ctttctcccc accagagata gattgaaaaa acattggtag
    31141 ccgcccagaa tatccactgt tcacggtaaa cagctgtcat gaggatttgc cctaccccat
    31201 tggttgcatc tgtgattgaa tcacgatagg gacgattggc accaatagac tgataaatga
    31261 agccaaaggc caaccaccaa agcacactaa tggaaagata ctttgtccag cccttgccgt
    31321 ccagtttacg cgcgacaaac tcctgctttt ccttcttaaa ctgtgcctga taaatccaaa
    31381 ctagaagtcc aattggctgc atgactgtga agtaaagtgt cgtcagcacc tcaccataaa
    31441 agcctttctg tagggccaaa ataaggtaaa taacagagtt aatcaagcca aaaagataat
    31501 tacttgctcg accttccgat acaaagatta cacagataat ccctgtcaag ctacaaatca
    31561 tcccaatcca gtcaacaata cgatgttcgt aaaccaactc cagccagaga ggaaaacttc
    31621 ctaaaaccag caaataaatc cactgggcaa aactacgatg ggcaaagagg tcatcccaga
    31681 tagccttcat agttcctgaa aatcctaaat cagccatagc cgcaaccata cgacggtaac
    31741 cacctgacat ttcacctagg gttgttttga tattttcaat tttcttttgc aaataagtat
    31801 gcatcatttc tccttttgtt tttaaagagc cgtgtctgga tagactttcg gacgcaacgc
    31861 tctattagat aatgaactgc ctatacacaa gatttctaac cttagtcgac atgagctgaa
    31921 acctcttatt tgttaagtag ttcacaaaat attatacacc tattttatga atagtcaact
    31981 gtctttacag taaaatttta gaaaatcatg aaaattttct ctttctttcc attttaagtg
    32041 acattcagtc attctcacat caaaaaagcc cagacgaaac tgtctgagca ttcttttatc
    32101 tagtcgttta aggaagttga gttcagtatg tttaaagtct ctgtcccatc atttcttcaa
    32161 caaaccttgt tcttggagaa actccttggc tacttgcttt gctgacttgc cttcaacacc
    32221 gacttggtag ttgagctggc tcatctggct ttctgtaatc ttaccagcca atgtattaag
    32281 aactctttcc aactctgggt gtttcttgag aagagcttct ttcatgagtg gagccccttg
    32341 ataaggtggg aagagttgct tgtcatcttc caagacctgt aaatcataac gctccaattc
    32401 cgcatcagtc gaataggcat ccgtgatttg aatatcccct gactgaattg cctgataacg
    32461 aagagctggc tgcatagtcg ccacattgag attgagacca tacattgatt gcaagccctt
    32521 atttccatct tcacggtcgt taaactcaag cgtaaagcct gccttcagct gcccttccac
    32581 ttttttcaaa tccgaaatgg tcttcaagcc atattcttga gcaatctttt tcggaacagc
    32641 tacagcatag gtattttgat aagacatagg tttgagatag gctagatgat cctgcttggc
    32701 aataccatca cgcgccactt gataaacctg ctctggctca tgactcacct tgggtgatgg
    32761 ttgaagcaaa ctttcagtca ccgtaccggt aaattcagga taaatgtcaa tatcaccttt
    32821 tttcagagct tcataaagga aacttgtcgt cccaaaattc ggtttaacag tcgcagtcat
    32881 gctggtattt tcttcaatca gcaatttata catattagcc aaaatttctg gttctgggcc
    32941 tattttccca gcaataacca agttttcctt ctctttttga gccaaaaggg ctggactata
    33001 agacagaccc agtaataaag ccaccaaggc aaaaccagag aaaatcgtcc gcaatttcgc
    33061 tttttccatt acttttagta ggaagttaaa ggcaatagct agcactgcag aagaaagggc
    33121 cccaatcaaa atcaaactgg cattattacg gtcaattccc aacaggataa aggaacccag
    33181 tccccctgcc ccaatcaagg tcgccaaggt agccgtaccg ataatcaaga ccgctgccgt
    33241 ccgaattcca gacatgataa caggcatggc aagtggaatt tcaaacttct tgagacgctc
    33301 ccatctggtc atcccaaagg caatcccagc ctcttgaaga ctcggatcaa ttcccttcag
    33361 cccagtaata gtattttgta aaatcggaaa aatcgcataa atcactagag ctgtcaatgc
    33421 cggtaaagtc ccaattccca tcaagggaat aaagagtccc aacaaggcca gagacgggat
    33481 ggtctggaaa atacctgcaa tctgcaagac ccagtcggcc agcttctcat gatagcgaag
    33541 aaaaacagcc aagggaatcg caagcaaaat agctagtaac aaggtcaaaa gtgacaactg
    33601 caaatgttga gatagagctg tcaaccaatc actaaaacga tcctgaaaag ttgcaattaa
    33661 attagtcatg aacactacct ccaaacaagt ctgctacaaa gtctgttgca ggcgctttta
    33721 aaattgtctc gggattcgct acctggcgaa tttctccatc ctgcaagaca gcaatacggt
    33781 ccgccaactt caaggcttca tccgtatcat gggttacaaa aatcgttgtc atcccaaact
    33841 ctttatgcaa ttcttttgtc agaacctgca actgttttct cgaaatagca tccaaggccg
    33901 aaaagggttc atccatgagg aaaatcttgg gctgaccaat catagctcgg acaataccga
    33961 cccgttgctg ttctccacca gataattcac taggtaagcg atgcccatac tcggctactg
    34021 gtaaaccaac cttagccaaa agctcttctg ttttcttcgt aatttcttcc ttgctccacc
    34081 ccttcatttc aggaatgaga gcaatatttt ccgcaactgt tagatttgga aaaagagcaa
    34141 tagcctgtaa aacataacca gtagaaagac gaagttcacg ctcatcatag tctttgatgc
    34201 gcttcccatc catataaata tttccatcag ttggttccaa aagacggtta atcatcttga
    34261 gcatggtcgt cttacctgat ccagaaggcc ctactaaaac cataaattcc ccatcttcaa
    34321 tctgtaagtt gacatctctc aagacatcct tttctgtgta gcgcagtgct acatttttgt
    34381 attcaatcat tctttgtcct caatttaaaa cttccctcga ttagtcaagt cttctacctt
    34441 aggcatgact tccttattat cccaatgctc cacaattttc ccgttctcta aacggaagat
    34501 atcgtactgg gcataagcaa cgccatcaat ctgagtctga ccatagctaa ccacatagtt
    34561 tccttgtcct aagagttgga aaacaaagtc aaaagtgaca ctatattcag ccacatagtt
    34621 tttataagca gcacttcctt gtccaatctc atgattatgc tgaatcaaat cgtctgccac
    34681 ataatcactc cactgctcta gctccccatt ttggaaaatt tctgtcaaga aacggcgaac
    34741 cagcttttta ttttctgctt tcttgtccaa atccttgatt tcaaaatctc caaaaatttg
    34801 atctagttgg tcattttcag gtgttcgata gtagtcaacg acatcccaat gctcaacaat
    34861 acgaccattc tcatccgcac ggaaagtatc cgtcgtcacc cattgagctt ctccaccatt
    34921 cagatattga tgaacatgaa caaagaccag attgccatcc tcaatggtgc ggacaatctt
    34981 aatctgacgc tctggatgac gctcaaagaa atctgcaaag aaggctgcaa atccttcttt
    35041 cccgtcagga acacctgtcg aatgttggat ataggtatcc cctacagact gggcttgagc
    35101 ctcagcaact cgtccgtctt gaatggcatg gatgtatagg ttgtgagcat ttttcacttg
    35161 ttgtgacata ttctaaacct catttccctt ctctttcaga ttcgccaaaa ttctttcttg
    35221 aaaaccttca aattggtgaa tttcttcctc tgaaaatcct ttgtaaaaga tagtatccaa
    35281 tttctgactg acacgatgcc ccacttcttt ctgggacttg cctaactccg ttaaaactaa
    35341 atacttctta cgcttgtctt ttccacacgg actaacaatt acaagctttt gttcctctag
    35401 cttttttatc atagtcgtta gcgtattatt cgcaagccca gtcgcaagcg cgatatctgt
    35461 cgcagttgcg cagccagttt cactattcca taaaaccgct aaaatcttgc cctgttcacc
    35521 cctataaaga gcctcaggat cttgactcag taacttttga aaaatccgcc cattcaacaa
    35581 acgaatatga tgggctagca aatgaccatc tttcataaca cctccaattt atttcgatat
    35641 cgaaatgaat aaaacaattg taacactcat cgttctaact gtcaactatt tcgatttaga
    35701 aataattttt gataattatc cacaccacca tactccggct caactaactt ttaacgagag
    35761 tttctaaact ccttcgtcct ccagtctaca aaagccttcc attcgtacta tcctatattt
    35821 tatgagggga cacatttttc ctatcagacc atttatttta aagatagaag taaatcataa
    35881 ttgcttccat ctgttctttt atagtatatt gaagttagac tagagcactg tatcttctaa
    35941 aacattgata gaaagcgatt tgaatttccc aatcaatttg ttcgtattta tagcatttcg
    36001 aaactggaat aggacaccat gactgctaaa agatttctat aaattcattt gattttccta
    36061 atcaatttgt tcatatctta tttcattccg ctataatttc accttaccct atctttttcg
    36121 tagcaccctt caaacagcct atcccctacc gtttgacgat tcctcacttc gctccacttc
    36181 cattacagaa gtttcttcac tactatgggc tcggctgact tctcatgatt ccttgttact
    36241 actatttgaa cgctcacgag atagatctta caaaaaatgc tttgatccac aatggaatca
    36301 aagcatttta aagagttcct catacataag cgcagaagtc gcagttcctc tgtacttggc
    36361 ttcttctctt ttgataaagc gagccaagtt gagcaactca ggtgctagat gtttgggatt
    36421 taggagcaat tcacgattga ccaggcctga gagacgaact gcctgcaatt gctcatttgt
    36481 agtaggcagt tttttagcag tctctaggag agcagcaact aaatcttcac tcaaatcatg
    36541 tcgagcatga ttgtaaagat cttttataag gctttctagg tttggttctg ccatccctac
    36601 cacctccctt atggtttaat aatgtttaat caaatcaacc gttgaacgat ccaatttctt
    36661 caccaaggct tgtaagaaag cttgcgcttc taggaagtca tccattgcat agagggtttg
    36721 gtgagaatgg atataacgag cgcagacacc gatagttgtt gatgggacac caccattttt
    36781 cagatgagct gcacctgcat ctgttccgcc tttaccacag tagtattggt acttgatacc
    36841 agcttcttca gccgttgtca aaaggaaatc cttcatccct gggagaagca agtgacctgg
    36901 atcatagaaa cgaatcaagg ttccatctcc aatcttgcct tgaccaccgt agacatcacc
    36961 tgctggtgag caatcaactg cgaggaagac ttctgggtca aacttggttg tagaggtatg
    37021 agcgccacgc agaccaactt cttcttggac gttagaaccc agatagagtt cattgccgag
    37081 tttttgacct gataaagctt cagctagctc gcttaccatg aggacaccgt agcggttatc
    37141 ccaagctttt gagatgatat ttttttcatt ggctgtcaaa attgcagaac tatctggtac
    37201 gatggtatca ccaggacgga tgccaaaact ttctgcctca gccttgtccg caaaaccacc
    37261 atcaaaaacg atatcggcaa tggctggcat ggttggtccc ccctttccac gagtcaaatg
    37321 cggaggaaca gaacctgaaa tcacaggaat ttcatgacca tcacgagtca agagtttgaa
    37381 acgttggctg ctaaccacca tggggttcca gccaccgatt tctacgacac ggaaggtacc
    37441 atctggcttg atttcgctga ccataaaacc aacttcgtcc atatgagaag cgaccaagac
    37501 gcgcggtgca tccacagctt ctgaatgttt gataccaaaa ataccaccca agccatctgt
    37561 caccacttca tccacatgcg gtgtcaactt ttcacgaaga taagcacgga caggcgcttc
    37621 atgacctgag actgcagcaa gttctgttac ttctttaatt tttgaaaata atgttgtcat
    37681 ttcagttcct tctttctttc atccatttta ccacttttta taggagaagg atagtgggaa
    37741 ggtggatttc taagttagta tcttagtcct gctctatctt agaaaaggat agtattctct
    37801 tgcatgtagt gcaaaatcta gtaaacattc caaaattaac tcgaatattt atttccaaac
    37861 aaaaaaacaa tacaccatca aagttgtttg tatttttcat gaaatttaca gaaaatagtt
    37921 gacttccctt tcttctttct ttaaatatat agttggttga gtttggaata gtacgctgta
    37981 gctgctaaaa catttctaga aattaatttg actttcctaa tagagttgtt catatcttat
    38041 ttcaattcac tatagtacaa aactagaaaa ggaaaaaatc atgaccaaaa caattcttgt
    38101 tacaggtggg actagctaca ttggctccca taccgttaaa gctcttttaa atgctggtta
    38161 taaggtgcat gtcctcgata atctctccac aggaaatcga gcggctgtgg atagtcgtgc
    38221 tagctttaaa gaactggatg tttatgatgc tagcgcctta aaggcttact tagaagaaaa
    38281 tcagattgat gctgtcctcc attatacagg tgaaattgtt gtgagcgaaa gtattgaaaa
    38341 tccaagtaaa tacttcactg ccaacgttgc tggtatgaac caagttctca aagtcttatc
    38401 tgaagttggc attcaaaaaa tcatgttctc ttcgactgct tctctctatg gaaataactg
    38461 tattgacaag ccggtgactg aagataccct gctcgaccct gtcaaccctt atgcagagac
    38521 aaaactgatg ggcgaacgaa tgatttactg gatggccaat cgctacgact ggaaatatgt
    38581 tattttccgt tactttaatg ttgctggggc tgaaatggat gcttcaaacg gtctgcgtgt
    38641 gaaaaatcca actcacatca ttccaaatat caacaagacc gcattgggac aaaatgatag
    38701 cttaaaaata tttggagatg actacgatac acgtgacggt tcatgtattc gagattacat
    38761 ttatgtcttg gaccttgcat aggctcatgt taaaggaatg aactacctat ttcaagaaga
    38821 cagttcttct caaatcttta acttaggaac taaaaaaggc tatactatca aagaaatctt
    38881 taaaactgct gaagaattac taaattaaaa aatcccacac gagattgttg ctcgacgtgc
    38941 tagtgaccca gccagtgtcc tagtagatgc ttcaaaagct aaacaatatc ttgattggac
    39001 ggctagctac tccctcgaag atattatttt atcagattaa ggtaaaaaca ttttagaata
    39061 ggataacaaa ggagaaagtc ttgttgctct ctccttgttg tatttattaa attgtcagaa
    39121 attttattga cagattagaa aaataatgtt acatttatat ccgcaggtat ctttcgatac
    39181 caaatctaca taaaaggacg gggtatgaaa ctttctcatt atttaattgg cttacttcta
    39241 ctcctagtct ttctctctat tagcattggg accagtgatt tttcatgggg aaagctattt
    39301 gatttcgacc agcagacctg gctcctcttt caagagtccc gtctcccaag aactatcagt
    39361 attctcctga ctgcctctag tatgagtatg gcaggccttc tcatgcagac tattacccaa
    39421 aatcagtttg ctgcaccgag tacagttgga acgactgaag ccgccaaact ggggatggtg
    39481 ctgagccttt ttgtctttcc atcggctagt ctgacccaaa agatgctctt cgcttttatt
    39541 tcatccatcg tattcaccct cttcttccta gcctttatga ccatttttac tgtaaaggaa
    39601 aggtggatgt tacctctgat tgggatcatc tatagcggaa ttatcggctc agtcacagaa
    39661 gttatcgcct atcgtttcaa tctggttcag agtatgactg cctggaccca gggctccttc
    39721 tccatgattc agacccatca gtatgagtgg ctcttcttag gcctcatcat cctgataacc
    39781 gtttggaaat tatcccaaac cttcaccatc atgaatctag ggaaagaaac cagcgagagt
    39841 ttggggattt cctactccct acttgaaaaa ctggccctct ttctggtggc gctaacgaca
    39901 agcgtcacca tgattaccgt gggtggccta ccatttctcg gagttatcgt tcccaatctt
    39961 gttcgcaagc gctatggaga taatctaagt caaaccaaac tcatggtcgc actggttggt
    40021 gccaatctag ttctggcttg cgatatccta tcccgagttc tgattaggcc ctatgagttg
    40081 tctgtcagtc tcttgctagg aatcatcggt agtctcgtct ttatcctact tctctggaga
    40141 gggggacgaa aagatgcaga ctaaaagcaa acataccaag ctcttctgga ttctcattat
    40201 tcttgccatc ggagcttgtc ttctctactt ttggcccatc actcacttgt cagcctttgc
    40261 ttggaagttg cgttcccaaa agatcatcgt ttatctcttg gtagccatcg cgactgggat
    40321 ttcgaccatt agttttcaaa ccctgacgga aaatcgcttc ctgacgccta gtattttggg
    40381 aattgaatcc ttctacgtcc tactacaaac cctactactg gtttttgaaa gcaagtttct
    40441 tcaacttggc aaatccccta tcttagaatt cctagtctta cttcttgtcc agtccctctt
    40501 ctttctcgcc ttacaaggtt acttgaagac actgatgaag caagacctgg tcttcatcct
    40561 gctgatctgt ctagcgctca gaagtctctt tcgaaatatc agcaccttcc ttcaagtcct
    40621 aatggatcca aacgaatacg ataaactgca aaatagtctt tttgcctcct ttcaacatct
    40681 taacacttcc atcctagcca tcggttctct gatcatcctc gctttgacaa tctttttctt
    40741 tcgaaaagca gtcgttctag atgtcttgca cctgcaaaga gaaacggctc agatattggg
    40801 actcgatgtt gaaaaagaac agaaagagct cctctgggga atcgtgcttt tgacctcaac
    40861 ggccactgcc ttggtaggac ctatggcctt cttcggcttt atgctggcca acctcaccta
    40921 cctgattgtc aaagactatc agcacaagtt actctttata gtggccattc tggttggatt
    40981 tattagctta accttggggc aagccttgat tgaacgagtc tttgcactgg aaattcgtat
    41041 cagtatgatc attgagagtg tgggtggctt cttattcttt atcttactat ataggagggc
    41101 tcgtcagtga aactggaaaa cattgacaaa tccattcaaa aacaggatat tttgcaaggc
    41161 atttcgcttg aagtcagtcc tcaaaaactg acagccttta ttggtccaaa tggtgctgga
    41221 aaatcgactc tcctctccat catgagcaga ctaaccaaga aagatcaggg agttctcagt
    41281 atcaaaggac gtgaaatcga gagctggaat tcgcaagaac tggcccaaga actaaacatc
    41341 ctaaaacaga aaatcaatta ccaagccaaa ttgactgttg aagaactggt cagttttgga
    41401 cgttttccct acagccgagg tcgacttaga tcagaagact gggaaaaaat ccgagaaact
    41461 ctgaactatt tggaactgac caacttaaaa gaccgctaca tcaatagcct gtcagggggg
    41521 caactccagc gcgtctttat cgctatggta ctggcccagg atacggactt tatcttgctg
    41581 gacgaaccac tcaacaatct cgatatcaag caaagcgtca gcatgatgca aattcttcga
    41641 cgactggtgg aggaactcgg caagaccatt atcatcgtcc tccacgatat caacatggcc
    41701 agtcagtatg cagatgaaat tgtcgccttc aaggacggtc aggtctttag caagggaagc
    41761 accgatcaaa tcatgcaggc tgacctgctc agccaacttt atgagattcc catcacgcta
    41821 gctgatatca atgacaaaaa gatctgtatc tatagctagt aacataaaag ctcaagttag
    41881 agaaccttca gtctcttaat caataagatc aagagactcc ctaaatcgtt atcacatttt
    41941 aaaaaggaga aattatgaaa acatccctta aactttattt cactgcccta gtggccagct
    42001 tcttgctcct acttggtgca tgtagtacaa actcaagcac tagtcagaca gagaccagta
    42061 gctctgctcc aacagaggta accattaaaa gttcactgga cgaggtcaaa ctttccaaag
    42121 ttcctgaaaa gattgtgacc tttgacctcg gcgctgcgga tactattcgc gctttaggat
    42181 ttgaaaaaaa tatcgtcgga atgcctacaa aaactgttcc gacttatcta aaagacctag
    42241 tgggaactgt caaaaatgtt ggttctatga aagaacctga tttagaagct atcgccgccc
    42301 ttgagcctga tttgattatc gcttcaccac gtacacaaaa attcgtagac aaattcaaag
    42361 aaatcgcccc aaccgttctc ttccaagcaa gcaaggacga ctactggact tctaccaagg
    42421 ctaatatcga atccttagca agtgccttcg gcgaaactgg tacacagaaa gccaaggaag
    42481 aattggccaa gctagacaag agcatccaag aagtcgctac taaaaatgaa agctctgaca
    42541 aaaaggccct tgcgatcctc cttaatgaag gaaaaatggc agcctttggt gccaaatctc
    42601 gtttctcttt cttgtaccaa accttgaaat tcaaaccaac tgatacaaca tttgaagact
    42661 cacgccacgg acaagaagtc agctttgaaa gtgtcaaaga aatcaaccct gacatcctct
    42721 ttgtcatcaa ccgtaccctt gccatcggtg gggacaactc tagcaacgac ggtgtcctag
    42781 aaaatgccct tatcgctgaa acacctgctg ctaaaaatgg taagattatc caactaacac
    42841 cagacctctg gtatctaagc ggaggcggac ttgaatcaac aaaactcatg attgaagaca
    42901 tacaaaaagc tttgaaataa gccacttcaa actcaattta atactcaatg aaaatcaaag
    42961 agcaaactag gaaactagcc gcaggttgct caaaacactg ttttgaggtt gcagatgaaa
    43021 gcagacgcgg tttgaaggga ttttcgaaga gtataaaatt ttgacattct aaaacgcatc
    43081 ctatcaaatt cactcaaacc tgataggatg cgtttttatc attttgaaat ctatttaccc
    43141 cacctcattc cccttcttga tttcgtttaa gggaaaagtg gtctggaacg gggtccttac
    43201 ctgttttcga ccagggatga caacgtaaaa tccgagccaa gcccatcaat acccccttaa
    43261 aaccatgttt ttcaatagcc tgaatcatgt agttggaaca agtcagctca aagcgacaag
    43321 agggtggaaa gactggtgag ataaaacgtt ggtaaaagcg cacaggcgct attaaaattc
    43381 gtttcattat ttcttagtta cagccatggt gtgtagttgg ctgatttctt ttttattaag
    43441 acgacgggat tctcctggac ggagtcctgt caagtctagg tgtccgaaac gagtccgaga
    43501 caacttatct acttggagac caacagcttc aaacatcttt ttaacctgat ggttacgccc
    43561 ttcatggatg gtcaactgca ccacagagcg atttttgact gggtccactt tgagaatttc
    43621 ataaacagct ggcttggttt tcttaccatc aatctcaaga ccacgggtca aggggcggag
    43681 attgtcctta ttggccacac ctttaacacg cgcgacataa accttgtcaa tctcattacg
    43741 agggtgaatc atctcgtctg taaagtcccc atcattggtc aaaatcaaga cacctgatgt
    43801 atcccagtcc aaacgaccca cagggtaaat acgttctttg acattgggca agaggtcgac
    43861 aaccgtcttg cgacccttat catctgtcac actggaaatc acaccgcgtg gtttgttaag
    43921 cagatagtag accttttctt cgttgtagat aggttgacct tcaacttcga ccttgtcgcc
    43981 tgacttgata gtggttgcta gttcacgcac cacttggccg ttaaccgtca ccaagccttg
    44041 cttaatcagc tcttctgctt ttctcctact ggccacacct gcgtgggcaa tatacttatt
    44101 gattctcatc ttcttctatc ctttcaccaa ataattggct ttcttgggct tgaatctcaa
    44161 gctcatcaat cactggtaat tcttctaaat ggtttatccc catgtaatct aggaaataat
    44221 ccgtagtcac atagaggttg gggcgcccca atacttcctt tttcccgtct tcctttatca
    44281 ggtcaaaagc ctgcaacttt gccaaggctc cactcgagtt aaccccacgg atggcatcaa
    44341 tttctatccg cgtaatcggc tgtttgtagg caataatgga caaggtctca agggcagccc
    44401 gagacaagct ctggttgata ggcgccttag agtattcctt caaaatttct gcaaattgag
    44461 gcttggtcac caatctataa gcaccacttg tctcaatcaa agccaaactg gaatctgggt
    44521 ccttttcata cttctgggct aattttccta aactttgctg gatacctgtc ggtggcagag
    44581 agaggagttc agctaactgg cggacccgaa tcccatcttc acccgctaca aacaagagcg
    44641 cttctatttt tgctaaagta ctcatctttc ctctctatca agtctagctt tgaggcactt
    44701 gactttcttc cttcttttcc atgagataga tatctccgaa actctcctct tgcacgagga
    44761 tcagctcctg ggttttgatt aactctaggg ttgccaaaaa gagggtgatg atctcttgga
    44821 cattctgggc ttccttgaac aaatcctgca agcgcaattg atctcgtcca atcaaggatt
    44881 ctttcacaat aatcatcatg tcctcaatct tatactcatc ccgcaagata gtcgtgtgat
    44941 tttgtgcaaa ctcctctttt ttcttggcta ggatatttga aaaagccaaa aagaggtcaa
    45001 tggtcgtctt gtcatgcaca agctccgcat cttcgtaaat caactctgtc ggcgctttgg
    45061 aataatactg ggcccgttct tggtgcttgg cttccaagtg ctcacccaag agcttgaact
    45121 tgcgatattc ttcgatttga gagaggaggt cctgctccag gtcatccccc aagtctgtca
    45181 cttctgctac cttcggaagg agtttacgac tcttaatcag catgagctga ctagccatga
    45241 ccatgtactc acccgtcact tccagacgca tggcctgcag ggttgaaaca taggctagat
    45301 actgttcgat gacttccgta atgggcacat cgtagatatc catctggtac ttagaaacca
    45361 gatgcaagag caagtccagg ggtccttcaa aatcttttaa tttaatatcc attatctata
    45421 tttttctaag gtcaggactg tttttaatcc taattttttt gcaatttcgt acaaatcgac
    45481 cttgttttct atttgtctta gaataaactg ttcacgtaag acttgagctg ataaggatgg
    45541 aaaacctttc tccttgacaa aagattctaa ctgacgaaag gcccactgac gagaataggg
    45601 tttccctcct ctttcaaaaa gataggtccg ccccatcaag ggttccaatt ctgaaagcaa
    45661 ggccatggga atggtgacaa tcctctgttg ggaagccttg ctgattcgca gcacctgaaa
    45721 atccagattg atgtccgcaa ccttgatggc taaaatctca ctgggcaaga gccccatttc
    45781 taggattaag agcgctagca agcggccctc tggatggtcg ctttcctgcc aaaaagagtc
    45841 taggtataga atctctggct tttccgtctt cttttcagct tgtttggcta attccaagcg
    45901 gtaaaagctg tccacctctc ctttttgata gagaaagtag agaaattggt tacaggccga
    45961 aatctttcgc ttctgggcgc tgatttttag attggctagc tgggcttggt aaatcttgag
    46021 actggtctca gaaatccgct cacctaccat gtctaaaaat tgctccaaat catacttata
    46081 ggactgcttg gaattgacag acaagccctg tttttcctct aaaaaggctg aaatcctgtc
    46141 tctcattggc atcgaatctc atattcctta ctaaagtcat gcaagagggc attaacggcc
    46201 ttgaggatgg acttgcgcgt aataatccct tggaaaatac cctctgcatc cacaactggt
    46261 aagaaggact catctactag cttgtgcaag acctccgtaa tggtgaaatc aggcgaaaca
    46321 accgctacgt ccgtttttgt catatgaacg atatccgtat ccgccatgat ttcttggctc
    46381 aagtcatgct ccatctgata agccataata tctctgagtc caatcgtccc aacaaactgt
    46441 ttttcatctg tcacaacggg aacacgggta taggtcatct gactaagcaa gagggtcgca
    46501 tgatccgcat tgtgggtatc aatcaacaca gctagatttt tagcaggggt caaaaaagtt
    46561 tcctcctgcc ccaacaagaa agtctcaaac tccttggcaa tcatcggcta aactccttgg
    46621 acaaacctgg atacacctcg tgatctcgtg tcaaaaagtc cactttgaag taactatcat
    46681 caatctccac acgagcatag agacattctc tgatggtacc tcgtggttgg ctgatagaac
    46741 ctggatttag aaagaggatc ttgccttcca tccaagcact tggcacatgc aagtgaccat
    46801 agaggcagat agcggcctct tcctcctgag cccagtagtc caacttttga aagttgaaat
    46861 tgatgtcaaa caagtgacca tgagtttgga taatcttggt cgaaccaagc tcagtcacca
    46921 gacgttctgg gtagccggcg tagaagtcca tgttcccttt aacaacgcgg atgccctccc
    46981 aaagtggaaa atccggacgt agttcagaat cgccgttatg aaaaacggca tcgactttgc
    47041 ccacatagcg atcacggact tcttccacaa tcaagctatc gccatgggaa tcgctcatta
    47101 caatgatggt ttgctttgcc atgatggaaa tacctccaaa agtttcttaa cggctaaggc
    47161 acggtgagat tgactatttt tttcttccag ggttaattca gctgatgact cacctgtctc
    47221 tcctacaagg aagaggggat catagccaaa gccattttca cccttaggtt caaagttaat
    47281 ataacctgac cagtctgctt caacaactaa actttcctta tttgggctgg ctacgactag
    47341 ggttgtgtgg aactgagccg agcggtcctt gagttcaaag accatggcca attcgtgcaa
    47401 gagtttggaa ttattttcac ggtcagttgc tcccacacct gcgaaacgag ctgaccagac
    47461 gcctggtaag ccaccaagga catcgacttt gagaccagaa tcatctgcca aaaccatctt
    47521 gcccgttaat tgagaaatgg tttctgcctt aaggcgggca ttttcttcaa aggtcatacc
    47581 tgtttctgct acttcaggca ggtcagggta gtcattaaga ttttccacat cgtagcctaa
    47641 cttatcaaag atagctcgga attccttggt tttaccttcg ttacgagtcg caatcaacaa
    47701 ggtttctctg accttgcttg tctcaaagaa atcatgaaca ttgacccctt ctttaggcaa
    47761 ttctacatac aagagttgcc cattttcaac caagagcagg gccccatgac gttgaataac
    47821 ttccaagttt cgtcccattt cttgattaag catgtctacc acaaaggaga acaaacggta
    47881 ggtagaacca tagcgtaaaa cagtaactga aagcgggaaa ccatactctt catctccaaa
    47941 tattttggag aattcaaaca gaggaaaatc tgtcttatag tcgctcaaac tgttaacgcc
    48001 accaaaaata ctataagacc caacatacca gtcctggtca tccttatatt cataaatttt
    48061 atttgtcata attctacatg ctccacatga atctcttttt ccagccattc ttcaccaatt
    48121 tgtgcaaaac tttggctact ggctgttgtg taaaaacggt gatggagtgg tccagcatcg
    48181 cgaccacgat tgatttcaaa ataattgagt aagactgaga tatcccgtac gcactctgcc
    48241 ccactatcga tgagctgaac ctttggcccc atcacatttt ggataatagg gcgaaggagt
    48301 ggataatgag tacagcccaa aatcaggcta tccacctttc caaccaaggg acgcagggtt
    48361 tcatagacca ccttcttggt aacactggtt gacagggcac ctgactcaac caagggagca
    48421 aacttgggac aggccaagct ctccacctgt aagtcgggat ccagatcatg gattttctta
    48481 cggtatatgt ctgattgtac cgtcatgggc gttccaatca ctccgatttt cccaccttga
    48541 ctggacttga tggctgccga agctcctggc aaaattacac ccaagacagg aatatctagt
    48601 tgagccttga tttcttccca gacgaccgca gtcgcagtgt tacaagcaat gacaatcatt
    48661 ttgacatcct tagtcaagag aaagttgacc agctgccaag tatattcacg aatttgctca
    48721 gcaggacggg ggccataggg cgcccgcgcc gaatctccaa tatagacgat ttcttcatgg
    48781 ggaagctggc gcatgagctc gcgcacaacg gtcaagcccc cgacacccga atccaaaaaa
    48841 ccaattggtc gattatccat acagtcttct ttctagtctt ttttctgatt gatcgttcat
    48901 tatgattcct tgtactgaac gaactgaccg acagcttgat agaatgtcaa ctacctctct
    48961 cttaatcata atcaaatatc aatagaatgc aaggaaaaag tctcatccct aaaccataac
    49021 caacatagtg agaagtctgg aactttcatc ccagactttt ccttatttat tttttctttt
    49081 tattgttagc aagggctgcc ttttgttggc ggatgatttg gtggtaaact tgttgtacct
    49141 tagcttcgct tggtttttga ccatttgcac tcaaaagagt acgaactgct tcagcattca
    49201 aacgtgggtt gtcagcaaat tctttttcga tttgcttacg aaccaagtac attcctccaa
    49261 gagctcctcc tagaaaagct agcacaatca atacaattgc taaaagtaaa tccatcattt
    49321 ttctcctgtt tctttttgag tccctttcat tataccacaa actagccacc ctgaccagtt
    49381 tgttctacac tttcagggat ggaatagaca gcaaaaagaa ccctgctttt ctgaaaaaga
    49441 ggtctccttg ctaagtttat actcaatgaa aatcaaagag caaactagga agctagccac
    49501 aggttgctca aagcaccgct ttgaggttgc agataaaact gacacggttt gaagagattt
    49561 tcgaagagta ttaatttaca taaatagcca gtgtttgata gggtttgagt agaattttct
    49621 cagacacttc tgcatcttca tagtttgata tcaaaatctg tccattttgg tagactgctg
    49681 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    49741 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    49801 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    49861 tcggaccctg gatttcattt tctacattga tgtatttata ggatttacca gctttcaacc
    49921 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    49981 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    50041 ctaagagcat ctgataggca ttaagcgatt cgacatccac ataatcagcc atagaatcat
    50101 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    50161 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    50221 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    50281 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    50341 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    50401 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    50461 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    50521 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    50581 gacagtccac tgaaacctcg tccttaccga tcaaattgat cacatcaaat cggaaacctt
    50641 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattggaat
    50701 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    50761 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    50821 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    50881 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    50941 cgacacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    51001 aatctgaaat atcgtaacca ttatcccgtt gagggcttgg atagaatgga ttgagccaga
    51061 ccatatccac acctagtttg gctaaatagg gaattttttc gataatccca cggaaatccc
    51121 caataccgtt ttcagtggtg tctttgtaag attttggata gatttgatag actacttttc
    51181 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    51241 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gaacaaacta ggaagctagc
    51301 cacaggttgc tcaaaacact attttgaggt tgcagataga gctgacgtgg tttgaagaga
    51361 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tggatcgttg
    51421 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    51481 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    51541 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    51601 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    51661 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    51721 ggcttggttc aatgaccaga ccttgcccca tgacacctga tgcaaaaaca ggatccgtcg
    51781 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    51841 ctactagttc atggctcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    51901 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    51961 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    52021 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    52081 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    52141 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    52201 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    52261 ctgagccttg agcaatatta gaaagagcaa tcattggcca gagggcagtg ccaccagcat
    52321 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    52381 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggaccc gttaaacctg
    52441 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtgt
    52501 gagccaaaat caaggctgga atcaatgaca aaaaaggtac aaaaatcatg gaaatgactt
    52561 ctgggatatg tttgcgccag aaaatttcaa gataagacag actcaaacct gcaagtaagg
    52621 ctgggataac ttgggcttgg taaccaatac gattaacagt aaaataacca aaattccaaa
    52681 cccagtttgc tgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    52741 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    52801 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    52861 agaggaagtg attaacccct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    52921 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat ccaccaacaa
    52981 tcaaggctgg aataatcgga gtaaagattt ccgccagagt ggtcataaca ccttggacca
    53041 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    53101 aaacggctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    53161 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    53221 ccttcttatc atctcttaaa acaaagcgca tccgtgtcgc acagtgagtt acggcagtca
    53281 cattttcttt gcctccaatt gcctgaagca gatctttggc ttcttgttca aattttccca
    53341 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    53401 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    53461 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    53521 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    53581 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    53641 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    53701 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    53761 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    53821 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    53881 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    53941 cggactatct ggatatggaa ctaatcccaa atctcactcg ccaaattgct gagcagtcta
    54001 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    54061 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    54121 tcgtttcgat taaatcaaaa gtctatctcc aagacggacg ccaatttcag tttaccgaaa
    54181 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    54241 ctgagacacc agatctcagc ctttttcggc tctataatat ttgtagtggg taaatccact
    54301 atagatatta tggagcctat tttgtgta
//
LOCUS       DAVHSH010000009        46389 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000009 DAVHSH010000000
VERSION     DAVHSH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.009"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            650..2803
                     /locus_tag="VVR08_000645"
     CDS             650..2803
                     /locus_tag="VVR08_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6074600.1"
                     /translation="MKFGKRHYRPQVDQMACGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2816..4165
                     /locus_tag="VVR08_000646"
     CDS             2816..4165
                     /locus_tag="VVR08_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU6074601.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4335..5042
                     /locus_tag="VVR08_000647"
     CDS             4335..5042
                     /locus_tag="VVR08_000647"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU6074602.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAASFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5099..8824
                     /locus_tag="VVR08_000648"
     CDS             5099..8824
                     /locus_tag="VVR08_000648"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU6074603.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFKKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8917..10359
                     /locus_tag="VVR08_000649"
     CDS             8917..10359
                     /locus_tag="VVR08_000649"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU6074604.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10396..11418
                     /locus_tag="VVR08_000650"
     CDS             10396..11418
                     /locus_tag="VVR08_000650"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU6074605.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLLELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11415..11960
                     /gene="purN"
                     /locus_tag="VVR08_000651"
     CDS             11415..11960
                     /gene="purN"
                     /locus_tag="VVR08_000651"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU6074606.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12044..12553
                     /locus_tag="VVR08_000652"
     CDS             12044..12553
                     /locus_tag="VVR08_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6074607.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12578..14125
                     /gene="purH"
                     /locus_tag="VVR08_000653"
     CDS             12578..14125
                     /gene="purH"
                     /locus_tag="VVR08_000653"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU6074608.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDMTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADNIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14247..15509
                     /gene="purD"
                     /locus_tag="VVR08_000654"
     CDS             14247..15509
                     /gene="purD"
                     /locus_tag="VVR08_000654"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU6074609.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            15912..16400
                     /gene="purE"
                     /locus_tag="VVR08_000655"
     CDS             15912..16400
                     /gene="purE"
                     /locus_tag="VVR08_000655"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU6074610.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16387..17478
                     /gene="purK"
                     /locus_tag="VVR08_000656"
     CDS             16387..17478
                     /gene="purK"
                     /locus_tag="VVR08_000656"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU6074611.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17488..17715
                     /locus_tag="VVR08_000657"
     CDS             17488..17715
                     /locus_tag="VVR08_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU6074612.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17778..19076
                     /gene="purB"
                     /locus_tag="VVR08_000658"
     CDS             17778..19076
                     /gene="purB"
                     /locus_tag="VVR08_000658"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU6074613.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19131..23069)
                     /gene="strH"
                     /locus_tag="VVR08_000659"
     CDS             complement(19131..23069)
                     /gene="strH"
                     /locus_tag="VVR08_000659"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6074614.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23384..24100)
                     /locus_tag="VVR08_000660"
     CDS             complement(23384..24100)
                     /locus_tag="VVR08_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6074615.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24448..26235
                     /locus_tag="VVR08_000661"
     CDS             24448..26235
                     /locus_tag="VVR08_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU6074616.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26232..26708
                     /locus_tag="VVR08_000662"
     CDS             26232..26708
                     /locus_tag="VVR08_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6074617.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26736..27641
                     /locus_tag="VVR08_000663"
     CDS             26736..27641
                     /locus_tag="VVR08_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6074618.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27628..28443
                     /locus_tag="VVR08_000664"
     CDS             27628..28443
                     /locus_tag="VVR08_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6074619.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28450..28854
                     /locus_tag="VVR08_000665"
     CDS             28450..28854
                     /locus_tag="VVR08_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6074620.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29153..30319
                     /locus_tag="VVR08_000666"
     CDS             29153..30319
                     /locus_tag="VVR08_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU6074621.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30435..31472
                     /locus_tag="VVR08_000667"
     CDS             30435..31472
                     /locus_tag="VVR08_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU6074622.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31589..32802
                     /locus_tag="VVR08_000668"
                     /pseudo
     CDS             31589..32802
                     /locus_tag="VVR08_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
     gene            33254..38824
                     /gene="zmpC"
                     /locus_tag="VVR08_000669"
     CDS             33254..38824
                     /gene="zmpC"
                     /locus_tag="VVR08_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HEU6074623.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            39180..40034
                     /locus_tag="VVR08_000670"
     CDS             39180..40034
                     /locus_tag="VVR08_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6074624.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            40140..40697
                     /locus_tag="VVR08_000671"
     CDS             40140..40697
                     /locus_tag="VVR08_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEU6074625.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            40914..41678
                     /locus_tag="VVR08_000672"
     CDS             40914..41678
                     /locus_tag="VVR08_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU6074626.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            42291..43670
                     /locus_tag="VVR08_000673"
     CDS             42291..43670
                     /locus_tag="VVR08_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6074627.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            43684..44349
                     /locus_tag="VVR08_000674"
     CDS             43684..44349
                     /locus_tag="VVR08_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU6074628.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            44484..44642
                     /locus_tag="VVR08_000675"
     CDS             44484..44642
                     /locus_tag="VVR08_000675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074629.1"
                     /translation="MKIKDQTRKLATGCLKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRC"
     gene            44704..44877
                     /locus_tag="VVR08_000676"
     CDS             44704..44877
                     /locus_tag="VVR08_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6074630.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGWDQVGNFSKGQYTMMHS
                     LIYRTDLLRASQF"
     gene            44944..45354
                     /locus_tag="VVR08_000677"
     CDS             44944..45354
                     /locus_tag="VVR08_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6074631.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            45470..>46389
                     /gene="pavB"
                     /locus_tag="VVR08_000678"
     CDS             45470..>46389
                     /gene="pavB"
                     /locus_tag="VVR08_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU6074632.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVA"
BASE COUNT        13395 a         8756 c        10712 g        13526 t
ORIGIN      
        1 ttaattagaa aaaaattttt aaagtcttcg gagaagaaaa cagaaaaatc tgttaaaaaa
       61 taatcaaaac tataaatgat gaatctgaat caaaattatt ttgcgcatgt aaagaggagt
      121 cttatagtaa cgagtcaaaa aaggagtaac tatgaatcgt aatttagaac ggtgttatct
      181 attctgacta ggaatagatc ataccagagg tagcttagaa atagcagaga cattagaaat
      241 tgaagtaata aataggatgt cgtaagtgtt actatcaatg atttatttgt ttcaagcttg
      301 cctagggtga cagtaaaaaa tcaatttcct ttcaatagca tatttttagt gggcaggact
      361 cttgttctgc ctattttttt atccaaaaag tgcagttggg agggagatag gctcatttgg
      421 gaaggaagtc cagtttttgt ttagtgattg aggtaagata gttgttatca gatgagttta
      481 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc ttgacgtata tatgtgactg
      541 acttcgtcag tcctatctac aacctcaaaa cagtgttttg agcagcctgc ggctagtttc
      601 ctagtttgct ctttgatttt cattgagtat tagggaaaag gagatgaata tgaaatttgg
      661 gaaacgtcac tatcgtccgc aagtggatca gatggcctgc ggtgtagctt cattagccat
      721 ggtttttggc tactatggta gttattattt tttggctcac ttgcgagaat tggctaagac
      781 gaccatggat gggacgacgg ctttgggctt ggtcaaggtg gcagaggaga ttggttttga
      841 gacgcgagcc attaaggcgg atatgacgct ttttgacttg ccggatttga cttttccttt
      901 tgttgcccat gtgcttaagg aagggaaatt gctccactac tatgtggtga ctgggcagga
      961 taaggatagc attcatattg ccgatccaga tcccggggtg aagttgacta aactgccacg
     1021 tgagcgtttt gaggaagaat ggacaggagt gactcttttt atggcgccta gtccagacta
     1081 taagcctcat aaggaacaaa aaaatggtct gctctctttt atccctatat tagtgaagca
     1141 gcgtggcttg attgccaata tcgttttggc aacactcttg gtaaccgtga ttaacattgt
     1201 gggttcttat tatctgcagt ctatcattga tacctatgtg ccagatcaga tgcgttcgac
     1261 actagggatt atttctattg ggctagtcat cgtctacatc ctccagcaaa tcttgtctta
     1321 cgctcaggag tatctcttgc ttgttttggg gcaacgcttg tcgattgacg tgattttgtc
     1381 ctatatcaag catgtttttc acctccctat gtccttcttt gcgacacgca ggacagggga
     1441 gatcgtgtct cgttttacag atgctaacag tatcatcgat gcgctggctt cgaccatcct
     1501 ttcgattttc ctagatgtgt caacggttgt cattatttcc cttgttctat tttcacaaaa
     1561 taccaatctc tttttcatga ctttattggc gcttcctatc tacacagtga ttatctttgc
     1621 ctttatgaag ccgtttgaaa agatgaatcg ggataccatg gaagccaatg cggttctgtc
     1681 ttcttctatc attgaggaca tcaacggtat tgagactatc aagtccttga ccagtgaaag
     1741 tcagcgttac caaaaaattg acaaggaatt tgtggattat ctgaagaaat cctttaccta
     1801 tagtcgagca gagagtcagc aaaaggctct gaaaaaggtt gcccatctct tgcttaatgt
     1861 cggcattctc tggatggggg ctgttctggt catggatggc aagatgagtt tggggcagtt
     1921 gattacctat aataccttgc tggtttactt taccaatcct ttggaaaata tcatcaatct
     1981 gcaaaccaag cttcagacag cgcaggttgc caataaccgt ctaaatgaag tgtatctagt
     2041 agcttctgag tttgaggaga agaaaacagt tgaggatttg agcttgatga agggagatat
     2101 gaccttcaag caggttcatt acaagtatgg ctatggtcga gacgtcttgt cggatatcaa
     2161 tttaaccgtt ccccaagggt ctaaggtggc ttttgtgggg atttcagggt caggtaagac
     2221 gactttggcc aagatgatgg ttaattttta tgacccaagt caaggggaga ttagtctggg
     2281 tggtgtcaat ctcaatcaga ttgataaaaa agccctgcgc cagtacatca actatctgcc
     2341 tcaacagccc tatgtcttta acggaacgat tttggagaat cttcttttgg gagccaagga
     2401 ggggacgaca caggaagata tcttacgggc ggtcgaattg gcagagattc gagaggatat
     2461 cgagcgcatg ccactgaatt accagacaga attgacttcg gatggggcag ggatttcagg
     2521 tggtcaacgt cagagaatcg ctttggcgcg tgctctcttg acagatgcgc cggtcttgat
     2581 tttggatgag gcgactagca gtttggatat tttgacagag aagcggattg tcgataatct
     2641 catagctttg gacaagacct tgattttcat tgctcaccgc ttgactattg ctgagcggac
     2701 agagaaggta gttgtcttgg atcagggcaa gattgtcgaa gaaggaaagc atgctgattt
     2761 gcttgcacag ggtggctttt acgcccattt ggtcaatagc tagaaagagg agaggatgaa
     2821 accagaattt ttagaaagtg cggagtttta taatcgtcgt taccataatt tttccagtag
     2881 tgtgattgta cccatggccc ttctgctcgt gtttttactt ggctttgcaa ctgttgcaga
     2941 aaaggagatg agtttgtcca ctagagctac tgtcgaacct agtcgtatcc ttgcaaatat
     3001 ccagtcaact agcaacaatc gtattcttgt caatcatttg gaagaaaata agctggttaa
     3061 gaagggggat cttttggttc aataccaaga aggggcagag ggtgtccaag cggagtccta
     3121 tgccagtcag ttggacatgc taaaggatca aaaaaagcaa ttggagtatc tgcaaaagag
     3181 cctgcaagaa ggggagaacc actttccaga ggaggataag tttggctacc aagccacctt
     3241 tcgcgactac atcagtcaag caggcagtct tagggctagt acatcgcaac aaaatgagac
     3301 catcgcgtcc cagaatgcag cagctagcca aacccaagcc gaaatcggca acctcatcag
     3361 tcaaacagag gctaaaattc gcgattacca gacagttaag tcagctattg aaacaggtgc
     3421 ttccttggcc ggtcagaatc tagcctactc tctttaccag tcctacaagt ctcagggcga
     3481 ggaaaatccc caaactaagg ttcaggcagt tgcacaggtt gaagcacaga tttctcagtt
     3541 agaatctagt cttgctactt accgtgtcca gtatgcaggt tcaggtaccc agcaagccta
     3601 tgcgtcaggg ttaagcagtc aattggaatc ccttaaatcc caacacttgg caaaggttgg
     3661 tcaggaattg acccttctag cccagaaaat cttggaggca gagtcaggta agaaggtaca
     3721 gggaaatctt ttagacaagg ggaaaattac ggcaagtgag gatggggtgc ttcatcttaa
     3781 tcctgagacc agtgattcta gcatggttgc agaaggtgcc ctactagccc aactttatcc
     3841 atctttggaa agagaaggga aagccaaact cacagcctat ctaagttcaa aagatgtagc
     3901 aagaatcaag gtcggtgatt ctgttcgcta tactacgact catgatgccg ggaatcaact
     3961 ttttctagat tctactatta caagtattga tgcgacagct actaagactg agaaagggaa
     4021 tttctttaaa atcgaggcgg agattaatct aacttcggag caggctgaaa aacttaggta
     4081 cggggtggaa ggccgtctac agatgattac gggcaagaaa agttatctac gttattattt
     4141 ggatcaattt ttgaacaaag agtaatgttc gtgtttttag agttaaataa tttttaaact
     4201 gtgagaaaga ttcttcttgc agttttttct ttacaatttt tgaaaaacat ctgctattta
     4261 ttcggttaaa ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa
     4321 aggcgaactt taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata
     4381 caactgagga tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaacg
     4441 gtgtcaagaa ggagcagatt gcaggtaagg gagtcttgaa taatcagatc tcatctttta
     4501 tttttgagaa attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca
     4561 cggaacaact caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata
     4621 ctgctgcttc cttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga
     4681 ttgtcgaatt ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg
     4741 tgaaattcct acagattgcg gatgaccagc agattgccta cttgaaggaa gaaacgcgtc
     4801 gtatcaatga actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta
     4861 agctagagtt cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag
     4921 ataactgccg cttgtgggat gctgatggca accacatgga taaggatgtt ttccgtagag
     4981 gattgggaga actaaccgac gtttatgaga ttgtttggga aaagttgcag ggtttaaaat
     5041 aacaacctca aggctgtttg ggaatattgc aagagctgaa ataaaggaat aagaattgat
     5101 ggataaacgt atttttgttg aaaaaaaggc tgattttcag gtcaagtcag agagtttggt
     5161 tagagagctc cagcacaacg tgggactgtc aagcttgaaa agtattcgta ttgtgcaagt
     5221 atatgatgta tttgacttgg ctgaggactt gtttgcacct gcagagaagc acattttctc
     5281 tgagcaggga accgaccatg ttttagatga agtatctgtg caggcggatc ttgctaacta
     5341 tgctttcttt gccattgaaa gtctgccagg gcagtttgac cagcgtgcag cttcgtcaca
     5401 ggaagccttg cttttgttgg gaagttcgag tgacgtgaca gtcaacacag cccaacttta
     5461 cttggtgaat aaagatattg atgcgactga gttggaagct gtcaaaaact acctgctcaa
     5521 tccagttgat tctcgtttca aggatatcac gacagggatt gccaagcagg agttttcaga
     5581 gtcagacaag accattccaa aattgacttt ctttgaaagc tatacagcag aagactttgc
     5641 tcgctacaag gccgagcaag ggatggccat ggaagtggat gatttgctct ttatccaaga
     5701 ctactttaag tcaatcgggc gcgtgccaac tgagactgaa ctcaaggttt tggacactta
     5761 ctggtctgac cactgccgtc atacgacttt tgagacagag ttgaaacaca tcgacttttc
     5821 agcttctaaa tttcaaaagc aattgcagtc aacctatgac aagtatattg ccatgcgcga
     5881 ggagttaggt cggtctgaaa aaccacaaac cttgatggat atggcgacta ttttcggtcg
     5941 ttatgagcgt gctaacggac gattggatga tatggaagtc tctgacgaaa tcaatgcctg
     6001 ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa ccttggctcc tcatgtttaa
     6061 aaatgaaacc cacaaccatc caacagaaat tgagccattt ggtggagcgg ctacctgtat
     6121 cggtggagct attcgtgatc cgttgtcagg ccgttcctat gtttaccaag ccatgcgtat
     6181 ttcaggtgct ggtgatatta cagcaccgat ttcggaaact cgtgctggga aattgccaca
     6241 acaagtcatt tctaaaacag cagctcatgg ttattcttca tatggtaacc agattgggct
     6301 tgccacaacc tacgttcgtg aatacttcca cccaggcttt gtagctaaac gtatggaact
     6361 tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc cgtgaaaaac ctgaagcagg
     6421 tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat ggtgtcggtg gtgcgacggg
     6481 ctcttctaag gttcaaacag ttgagtctgt agagactgct ggtgctgagg ttcaaaaagg
     6541 aaatgccatc gaagaacgca agattcagcg cctcttccgt aatggcaatg tcactcgtct
     6601 gatcaagaag tccaatgact ttggggcagg cggtgtctgt gtggctatcg gtgaattggc
     6661 agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa taccagggct tgaatggtac
     6721 agaaattgcc atctctgaat cacaagaacg gatggcggtc gtggttcgtc ctgaagatgt
     6781 ggataccttc gttgccgaat gtaacaaaga aaatattgat gctgttgtgg tggcgacagt
     6841 aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag acaatcgttg acttggagcg
     6901 tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat gccaaagttg tggacaagga
     6961 tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca ctggaatcag atacccttac
     7021 ggttctatct gacctcaacc atgcaagtca aaaaggatta cagactatct ttgactgctc
     7081 tgttggacgc tcaacggtta atcacccact tggtggtcgt taccaactca caccaactga
     7141 ggcatctgtg cagaaattgc cagttcaaca cggtgtgact catactgcgt cggtcattgc
     7201 tcaaggtttc aacccatatg tagctgaatg gtctccatac cacggtgctg cttatgcggt
     7261 tatcgaagca actgctcgtt tggtggctgc tggtgccaac tggtctaagg ctcgtttctc
     7321 ttaccaagaa tatttcgagc ggatggacaa gcaagcagag cgtttcggtc agccagtagc
     7381 tgctcttcta ggttctattg aagcacaaat tcagcttggc ttgccatcta tcggtggtaa
     7441 ggactccatg tctggtacct ttgaagaatt gaccgttccg ccaaccttgg ttgcctttgg
     7501 ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa tttaaagctg ttggggaaaa
     7561 tatctactac atcccaggtc aagccctctc tgcagagatt gattttgact tgattaagaa
     7621 aaattttgct cagtttgaag caagccaagc tgaccataaa gtgacgtctg catcagctgt
     7681 caaatacggt ggtgtagttg aaagtttggc tcttgctacc tttggaaact atattggtgc
     7741 agaggtgacc ttgcctgaac ttaaaacagc tttgacagct caattaggcg gctttgtctt
     7801 cacatctcct gaagaaattg ctggagtaga gaagattgga caaacgaaag cagactttac
     7861 actgactgtc aacggtgtga agctagatgg acacaagctt gacagtgcat ttcaagggac
     7921 attggaagaa gtttacccaa cagaatttac ccaagcgaaa gaactagaag aagtaccagc
     7981 tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt gaaaaacctg tggtttacat
     8041 cccagtcttt ccaggaacca actcagaata tgattcagct aaggccttca aaaaagaagg
     8101 tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa gaagctattg tcaagtcagt
     8161 tgaaactatg gttgacaata tcgacaagac taatattctc ttctttgccg gtggattctc
     8221 ggctgcggat gaaccagatg gttcagctaa gtttatcgtc aatatcctgc ttaatgaaaa
     8281 agtgcgtgtg gctattgata gctttatcgc ccgtggtggc ttgattatcg gtatttgtaa
     8341 tggattccaa gccttagtca aatcgggtct cctaccatac ggaaactttg aagatgctaa
     8401 cagtactagt ccaaccctct tctacaatga tgccaaccaa cacgtggcca agatggtgga
     8461 aactcgcatt gccaatacca actcaccatg gttggctggt gtgcaagtgg gcgatatcca
     8521 cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg acggctgagg aatttgcaga
     8581 gctccgtgac aatggacaaa ttttcagcca atacgttgac tttaacggta aaccaagtat
     8641 ggattctaag tacaatccga atggttctgt ccatgccatc gaaggaatta ccagcaagaa
     8701 tggtcaaatc atcggtaaga tgggccactc agaacgttat gaggatggtc ttttccaaaa
     8761 tatcccaggc aataaagacc aacacctgtt cgcatcagcg gttaaacatt tcactggaaa
     8821 ataagactta cagattttct aatagatagt atcagtaatg taaaagtcat gtaaatctag
     8881 ctcttgatga ttacaaatga aaattaggta taaaaaatga catacgaagt aaaatctctt
     8941 aatgaagaat gtggtgtttt cggtatttgg ggacatccag atgctgctaa gttgacctat
     9001 tttggactcc acagtcttca acaccgtggt caggaggggg caggaatcct ctccaatgat
     9061 caaggacaac tgaagcgcca tcgtgacatg gggcttttat cagaagtttt cagaaatcca
     9121 gccaatttgg ataaattgac aggagctggt gcgattgggc atgtgcgtta tgcgactgct
     9181 ggcgaagctt ctgttgataa catccagccc ttcctcttcc gttttcacga tatgcagttt
     9241 ggcttggctc ataatggaaa tctgaccaat gcagcctctc tcaagaaaga actggaacaa
     9301 agaggagcaa ttttcagcgc gacttcggac tctgaaatct tggctcacct cattcgtcgt
     9361 agtcataatc ctagcctgat gggcaaaatc aaggaagcgc tcagccttgt caaaggtggt
     9421 tttgcctata tcttgctgtt tgaggacaag ttgattgcgg ctcttgaccc taatggcttt
     9481 cgtccgcttt cgattggtaa aatggctaat ggagcagttg ttgtatcttc tgaaacctgt
     9541 gcttttgagg tcattggtgc cgagtggatt cgtgatttga agccaggtga gattgtgatc
     9601 attgatgacg agggcattca gtatgacagc tatacagatg atacccagtt ggcggtttgt
     9661 tctatggagt atatctactt tgctcgccct gattctaata tccacggtgt caatgtccat
     9721 acggcacgta agagaatggg agcacaattg gcgcgagaat ttaagcatga ggcagatatt
     9781 gtagttggtg tgcccaattc ttccctaagc gcggctatgg gatttgcgga agaatcaggc
     9841 ttaccaaatg aaatgggtct gatcaaaaac caatacaccc agcgaacttt tatccaaccg
     9901 actcaagaat tgcgggagca aggagtgcgg atgaaactgt ctgctgtttc gggtgttgtc
     9961 aaaggcaaac gtgtggtcat ggtggatgat tccattgtac gtggaacaac ctctcgtcgt
    10021 atcgttcagc tcttgaaaga agcgggtgcg actgaggttc acgttgccat tggaagtcct
    10081 gcactagcgt atccatgttt ctacgggatt gatatccaga cccgtcagga gctgattgca
    10141 gccaatcata cggtcgaaga aactcgccaa atcattggtg cggacagtct gacttatctt
    10201 tcaattgatg gcttgattga gtcgattggt atcgaaacag atgcgccgaa cggtggtctc
    10261 tgtgtcgctt actttgacgg tgactaccca acgcctctct atgactacga agaagactat
    10321 cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg cgacagattc tccattaaag
    10381 aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc agtcgggtgt ggatgttgaa
    10441 gcgggttatg aagttgttga acggattaaa aagcacgtgg ctcgtacgga gcgtgcaggt
    10501 gtcatgggag ctcttggtgg ctttggtggt atgtttgacc tttccaagac tggggttaaa
    10561 gaacccgtct tgatttcagg gactgacggt gtcggaacca agctcatgtt ggctatcaag
    10621 tacgacaagc acgataccat cgggcaggac tgtgtggcca tgtgtgtcaa cgacatcatt
    10681 gctgcaggtg cggaacccct ctattttctc gactacgtag cgacagggaa gaatgagcca
    10741 gctaagctag aacaagtggt tgctggtgtg gcagaaggtt gtgtgcaggc tggtgctgcc
    10801 ctcattggtg gggaaacggc tgaaatgccg ggcatgtacg gcgaagacga ctatgacttg
    10861 gctggtttcg cggtcggtgt ggctgaaaaa tctcaaatca ttgacggttc aaaggtggta
    10921 gagggagacg ttcttctcgg acttgcttca agtgggattc actcaaatgg ttactctttg
    10981 gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc tactagaatt ggaaggcaag
    11041 aaacttaagg aagttctact tgagccgact cgtatctatg taaaggctgt cttgccgctc
    11101 atcaaagaag agttggtcaa cggcattgcc cacatcacag gtggtggctt tatcgaaaat
    11161 gtccctcgta tgtttgcaga tgacctagct gctgaaattg atgaaagtaa agttccagtg
    11221 cttccaattt tcaaaaccct tgaaaaatac ggtcagatta aacacgaaga aatgtttgaa
    11281 atcttcaata tgggtgtggg actcatgttg gcggtcagcc ctgaaaatgt agagcgtgta
    11341 aaagaattgt tggatgaagc agtctatgaa attggtcgca tcgtcaagaa agaaaacgaa
    11401 agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc tggtaatggc tcaaattttc
    11461 aggtgattgc cgaagaattt ccagtggagt ttgtcttttc agaccatcgt gatgcctatg
    11521 tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc ttttgaactc aaggagtttg
    11581 agagcaaggc agactacgaa gcagcccttg tcgaactctt ggaagaacac cagattgact
    11641 tggtttgcct agcaggctac atgaaaatcg ttggaccaac cttattgtcg gcttatgaag
    11701 gtcggattgt caacattcat ccagcctact tgccagaatt tccaggagct catgggattg
    11761 aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac cattcactgg gtggattcgg
    11821 gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc acgactagct gatgatacca
    11881 ttgacagatt tgaagctcgc atccatgaag cagagtacag gctgtatccg gaagtagtga
    11941 aggctctatt tacagattga ctttttgatg attcatatga tatctttgat tttaaattgg
    12001 agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt gtaatgttag aatctaaaaa
    12061 aacaactcga tatgtatttt atgtctatct gatgttatta acttggggaa tcttatttaa
    12121 gtttgaaaca aatcctgaat ttatagcatt tttcttagct ccaaggtata tcaattggat
    12181 tccattttca gaaccactaa tagtcgatgg aaaaattgtt tttgctgaaa tgttatttaa
    12241 tctgattttc tttattccat taggtgtttg tttccctttg ataaaaacta atttatctag
    12301 tttaagaata gtcgggacag gtttcttgat tagtttattg tttgagtgct tacagtatat
    12361 tttagcaata ggtataacag atataacgga tttgacttta aatacgctag gtgtctgtgt
    12421 aggcttactg atttatcaaa tttttataag agtgttcaaa tcacagacta gaaaatggat
    12481 caatatctta ggtatgctta gccttggttt tgcttatctt gttttactgt tactgcattt
    12541 aattggtgtt taactaatga ttaaaaagga gaatataatg actaaacgcg tcttaatcag
    12601 cgtctcagac aaagcgggca ttgttgaatt tgcccaagaa ctcaaaaaac ttggttggga
    12661 gattatctca acaggtggaa ctaaggttgc ccttgataat gctggggtgg ataccattgc
    12721 tatcgatgat atgactggtt tcccagaaat gatggacggt cgtgtgaaga cactccaccc
    12781 aaatatccac ggagggcttc tcgctcgtcg tgacttggat agccacttgg aagcggctaa
    12841 ggacaacaag attgagctca ttgaccttgt ggtggtcaac ctttacccat ttaaggaaac
    12901 tatccttaaa ccagatgtga cttatgctga tgcagttgaa aatatcgata ttggtgggcc
    12961 atctatgctt cgttcagcag cgaaaaatca tgccagtgtt acagttgtgg tagatcctgc
    13021 tgactacgct gtggttttgg acgagttgtc agccaatggt gaaacgactt atgaaactcg
    13081 ccaacgttta gcagccaaag tatttcgtca cacagcggct tatgacgcct tgattgcaga
    13141 atacttcaca gctcaagtgg gtgaaagcaa gcctgaaaag ttgaccttga cttatgacct
    13201 caagcaagcc atgcgttacg gtgagaaccc tcaacaagac gcggatttct accaaaaagc
    13261 cttgccaaca gactactcca ttgcttcagc caaacagctc aatggtaaag aattgtcctt
    13321 caacaatatc cgtgatgcgg atgctgccat tcgtattatt cgtgatttca aagaccgtcc
    13381 aactgttgtg gctctcaaac acatgaaccc atgtggaatc ggtcaggctg ataacattga
    13441 gactgcttgg gactacgctt atgagtctga cccagtgtct atctttggtg ggattgtcgt
    13501 cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg cacggcgttt tcctcgaaat
    13561 catcattgca ccaagctata cggatgaagc gctagctatt ttgatcaata aaaagaaaaa
    13621 cttgcgtatc cttgccttgc catttaatgc tcaagaggct agcgaagtgg aagcagaata
    13681 cacaggtgta gtcggtggac ttctcgtgca aaatcaagac gtggtcaagg aaagcccagc
    13741 tgactggcaa gtggtgacca aacgtcagcc aactgagaca gaagcgactg ctcttgagtt
    13801 cgcttggaag gctatcaagt acgtcaaatc aaatggtatt atcgtgacca acgaccacat
    13861 gacacttggt gttggtccag gtcaaaccaa ccgtgtggct tctgttcgcc ttgccattga
    13921 ccaagccaaa gatcgtctga acggggcggt ccttgcttca gatgccttct tcccatttgc
    13981 ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc atcatccagc ccggtggctc
    14041 tgtccgtgac caagaatcca tcgaagcagc ggataaatac ggcttgacta tggtctttac
    14101 aggtgtgaga cattttagac attaagaaga taaaagggaa gaaaacagtt tctttccttt
    14161 tttggcttaa aatgctaact gaaacaagat taaaacgaac ttttttgata taatattggt
    14221 aaataattcg caaaagaggt tgaggaatga aactgcttgt tgtcggttcg ggtggtcgtg
    14281 agcatgcgat tgctaaaaag ttacttgaat caaaagacgt tgaaaaagtc tttgtagctc
    14341 ctgggaatga tgggatgact ctggatggtt tggaattggt aaatatctct atttccgaac
    14401 attctaaatt gattgacttc gcaaagacca atgatgttgc ttggaccttt atcggtccag
    14461 atgatgccct tgctgctggt atcgtggatg attttaacca agctgggctt aaggcctttg
    14521 gtccgactag ggctgcagcg gagctggagt ggtccaagga ttttgccaag gaaatcatgg
    14581 tcaaatatgg tgtttcgaca gcagcctatg gcacattttc agatttcgag gaagcaaagg
    14641 cctatatcga aaagcatggt gcgcctatcg tagtcaaggc ggatggcttg gcgcttggga
    14701 agggtgtcgt cgtttctgag acggttgagc aagcggtcga agccgctcat gagatgcttt
    14761 tggacaataa atttggtgac tcaggtgcgc gcgtggttat tgaggaattc cttgaaggag
    14821 aggaattttc actctttgcc tttgttaatg gtgataagtt ctacatcatg ccaacggctc
    14881 aggaccacaa acgtgcctac gatggcgaca aagggcctaa cacgggtggt atgggtgcct
    14941 atgcgccagt tccacactta ccacagagtg tagttgatac agcggttgac accattgtca
    15001 agccagttct agaagggatg attaaagaag gtcgccctta tctgggagtt ctttacgcag
    15061 ggcttatcct gacagctgat ggaccgaaag tcattgagtt caacgctcgg ttcggagatc
    15121 cagaaactca gattatcttg cctcgcttga cctctgactt tgctcaaaat atcacagata
    15181 tcctggatag caaggagcca aatatcatgt ggacggacaa gggtgtgact ctgggtgtgg
    15241 ttgtcgcatc caagggctac ccgctagact atgaaagggg cgttgagttg ccagccaaga
    15301 cagaaggcga tgtcatcacc tactatgcag gggctaagtt tgcggaaaat agcagagcac
    15361 tgctctcaaa cggcggacga gtttatatgc tcgttaccac agcagatacc gtcaaagaag
    15421 cccaagccag catctaccaa gaactatacc aacaaaaaat agaaggactc ttctaccgaa
    15481 cagatatcgg aagcaaggca attaagtaaa gatataagaa taacgcgccg tagtcgccaa
    15541 acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg aatgttctgg tcagggggaa
    15601 acttggagac cgtaggctca aagtttagga atgaaaccga aggtttgctt ccgcctccat
    15661 cacctaagac cattatcaaa aagaaaaata aaaattcaca aaatacgtta atgatcgtat
    15721 ggtttgcgag cgttagcgag ctaatataga acaatcaccg ccgttgtgaa agaacgattg
    15781 gatgataatc caatcgttca gggaaattgg aagaccttgg gtttccaatt taggcatgag
    15841 acacctttgg tggctgctgc cgtccctcac aagctaaggt gattgttgaa aaagaggaaa
    15901 aaggagaaga aatgaaacca gtaatttcca tcatcatggg ctcaaaatcc gactgggcaa
    15961 ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt agcctacgaa aagaaagttg
    16021 tttccgcaca ccgtacacca gacctcatgt tcaaacatgc agaagaagcc cgtagtcgtg
    16081 gcatcaagat catcatcgca ggtgctggtg gcgcagcgca tttgccaggc atggtagctg
    16141 ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc tcgtgctctt agtggagtgg
    16201 attcactcta ttctatcgtt cagatgccgg gtggggtgcc tgttgcgacc atggctatcg
    16261 gtgaagctgg agcgactaac gcagctctct ttgccctccg tctcctctct gtagaagata
    16321 agtccattgc ggatgcactt gccaactttg ctgaagaaca aggaaaaatc gcagaggagt
    16381 cgtcaaatga gctcatctaa aacaatcgga attatcggtg gcggtcaact gggtcagatg
    16441 atggccattt ctgctatcta catgggccac aaggttatcg cgctggatcc tgcggcggat
    16501 tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt ataacgatgt ggatgccctc
    16561 cgtcagttgg cagaccgttg cgatgtcctc acttatgagt ttgaaaatgt cgacgctgac
    16621 ggtttggatg ccgttatcaa ggatggacaa ctccctcaag gaacagatct gctccgcatt
    16681 tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca aggctcaagt cactgtggca
    16741 ccctacaagg tcgtgacttc tagcctagac ttggcagata tcgacttgtc gaaaaactat
    16801 gtcctcaaga ctgcgactgg tggctacgat ggtcatggac aaaaggttat tcgttcagaa
    16861 gcagacttgg aagcagccta tgcgctagca gactcagcag actgcgtctt ggaagaattt
    16921 gtcaactttg accttgagat ttctgtcatc gtgtcaggaa atggcaagga ggtgacgttt
    16981 ttcccagttc aggaaaatat ccaccgcaac aatatcctgt ctaagaccat cgtaccagcc
    17041 cgcatttctg aaagtctagt agacaaggct aaagctatgg cagtgcgaat cgcagaacaa
    17101 ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga ctgatgatga cgttattgtc
    17161 aatgaaatcg ccccacgacc acataactct gggcactatt ctattgaagc ctgtgatttc
    17221 tctcagtttg acacccatat tctcggtgtt ctcggagcac cattaccagt catcaaactc
    17281 catgcgccag ccgttatgct taatgtcctc ggtcagcatg tcgaggctgc tgagcaatat
    17341 gtgacagaaa attcaagcgc ccacctccac atgtatggta aaatagaagc gaagcacaac
    17401 cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg atagtgtgga tgagcttggg
    17461 gaagggattg atttttagga caagtctatg atacaaatta tcgttaatac atttattgaa
    17521 aaggataaga ctggagcagt tgttgaagtg ttgtatgcca gtgctgacca agataaggta
    17581 caagctaaat atgaagaact agctgcacaa taccccgaaa attatttagc tatctatgat
    17641 gtaccgctgg atacggattt gaatacacta gatcattacc cgtctgtgtt tattgaaaaa
    17701 gaggagtttg agtagaaatc ttggtttacc tagatagctt attcccaaca gcttaagaag
    17761 aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc tgagatggcg aatatttgga
    17821 gtgaagaaaa taaataccgt gcttggcttg aggtggaaat cctctctgac gaggcatggg
    17881 ctgagttggg ggaaatccct aaggaagatg tggctttgat tcgcaagaag gcggactttg
    17941 acatcgaccg tattttggaa attgagcagg agacgcgcca cgatgtggtg gctttcacgc
    18001 gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt tcactatggg ttaacttcta
    18061 ccgacgtggt ggatactgct tatggttacc tctacaagca ggccaacgac atcatccgtc
    18121 gtgaccttga aaacttcact aatatcatcg ctgacaaggc caaggagcac aagttcacca
    18181 tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac aacctttggt cttaaattgg
    18241 caacttggta cagcgaaatg aaacgcaata tcgagcgttt cgagcatgca gctgctggtg
    18301 tagaagctgg taagatttct ggtgcggttg ggaactttgc caatatccca ccatttgtag
    18361 aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga aatctctaca caagtccttc
    18421 ctcgtgacct tcacgctgag tactttgcgg ttcttgccag cattgcgact tcaatcgaac
    18481 gtatggcgac tgagattcgt ggtctacaaa aatctgagca acgcgaagta gaagagttct
    18541 ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa acgcaaccca atcggttctg
    18601 aaaatatgac tggtctggcg cgtgtcattc gtggtcacat gattacggct tatgaaaacg
    18661 tcgctctctg gcacgaacgc gatatttctc actcatcagc tgagcgtatc atcacaccag
    18721 atacgaccat tttgattgac tacatgctca accgttttgg aaatatcgtc aagaacttga
    18781 cagtcttccc agaaaatatg atccgaaaca tgaactcgac ttttggtctt atctttagcc
    18841 aacgggctat gttgacattg attgaaaaag gcatgacccg tgagcaagcc tatgacttgg
    18901 tgcaaccaaa aacagcctac tcttgggaca accaagtaga ctttaaacca cttcttgagg
    18961 cagattcaga agtaacatca cgtctcactc aagaagaaat cgatgaaatc ttcaacccag
    19021 tttattacac caaacgagtg gatgatatct ttgaacgtct tggactaggt gattaattaa
    19081 aaaataaaca gcgagcttca atctcgctgt ttatttttta tcgaaaagac ttagtcttct
    19141 tttcttttag tgagtccata ggctgctagt gtggacatga gtcctgcgac tactagtcct
    19201 gcagaatcgt gagttcctgt ttcaggaagt tttttctctg ttaccacagg agctggatct
    19261 tgaggaagag ctttgctttc ctcagcggga gcagttgatg gagctggttg gcttgggatt
    19321 tctagttttg gtttttcttc agcaatagcg gcttgtccgt tttcatcgcc tacatgtgtt
    19381 accatagttc cgacttcgac tatttgagta acggcttcct gtgctacgac actatttaca
    19441 agtgttttca cttccttacc atcggcagaa gtgctcacag agtagaagtt gctacgatgt
    19501 ccattgacgc ccttagtaat gacttgtgtt tttcctttga gtaagagtgg attttcacga
    19561 gtcactgtgg taaatggaat ttcttctttt tggatatcca gtctaggttt tacctcagta
    19621 gttggtgcaa gaccactttc atcacccttg tgagttacag gagcgccaac ttcaaccact
    19681 tggtttataa cttctttggt tacctggcta tcaaggactg tttctgttgt ttttccattt
    19741 tcagtgagta cagagatgta atgagttcgt tcacctttga ctcctgctgt gataatattt
    19801 tcctgaccag ctgggaggtt aggattttct ttcttgataa cttcaaatgg aatttcttca
    19861 gttcttgtga tgagttctgg tctggtttca acattggcag ccacttcatt ttcatccagg
    19921 cttcctgaat gagttgcagc tggtttgagg ccttgaagag cggcttttag gttggctaca
    19981 agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt aatttagagc tgttttagct
    20041 gcgtcaaggg cctcaagact ttctttacta tatccttcta agtttgtagg aattttagct
    20101 aattcttcgc ggagagcatt ataattagca cggaagtagt ctttgttgtg gtctgcaaag
    20161 gcagtcatga gttcaaagat ttcctcttcc ttgtactcag cgcttggtct atctgcccag
    20221 attgaaagca tacttccgac tgttggaaga tctacttcag gatatttggt agaagctagt
    20281 tgattgaatg gtgtttttcc agtattctca atagctttct tgaggaaacc accaccatct
    20341 tctggttttt gaccaagaat gtagtaccag tcaccgttgg tattcaagaa tttatagcct
    20401 ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc accagccttt agaccagtaa
    20461 gaaatcaaga catctttgtc aaactgaaca tcgtccttgt cttcatagta gaagccatcg
    20521 ttgaaggcca ttggttgaag ccctctttct ttggccatag ctgcgagggt gttggcatat
    20581 tcggcaaatt tgccatagag ttgataccac ttgaggtagt accagccttg ggcactagtc
    20641 gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct ttgttttacc tgcaaagaag
    20701 tccatgtatt taccgatgag ggcttttaca aagttcatcg cttcttcgtt tttcaagtcc
    20761 atagttgttt ttgaaacttt atcaaagtgg gcttgaggat ttttaatacc taatttttcc
    20821 atggcaacca gcatagcatc catgtgacct ggactgttaa tagctgggat gagaccgatg
    20881 tccttagatt tagcgtattc aattagctct gttacttctg cctgtgttag tgcagtaccg
    20941 tttggatcgt cgtagtaagc tttagttcct tcgataatag cttttttaac gtcatcacta
    21001 gcataggttt ttccgttggc agtaatggtc atatcatcga gtagaaagcg aagtccgtca
    21061 tttcctagaa ggagatggac atcagaatat ccgagctcac tggccttgtc tacgatgcgt
    21121 ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga ttgagattac cttgtttttg
    21181 gcaagttttt caacctcacg tttagcttct tcttctttta gagcttcagg cgtgagggtc
    21241 aagttgttga cagtttcttg aagtttagca atggcttgat caatcgtatc ttgttgggca
    21301 cggctaaggt tgctatcgag agagcgaata gctttttcag cttcttttac ggccgtgacg
    21361 ctttctgcag tataacggtt caggtctttt ggtacctcgt taagtgcttg ctctgcagat
    21421 tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa aatgacgcat gagtttgaag
    21481 aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc aagcagctac cataccaccg
    21541 atgattggga tatcagctcc ttctgttttt ggtacagaag tgattggtgt gtttttaata
    21601 ccattgagcc cctgatcgag attgtaccag ccttggccat cagcgtttcg tccaagaacg
    21661 tagtaccaag catcattggt attaaggatt tggtgacctt tttcagctag tagtttagaa
    21721 gaagcgacat cgtagcctcc ccaaccacca gtccacatag aaacgatgat gtctttgtca
    21781 aaactaccaa agcttgtgtc gctattgtag tagataccgt cgttaaaagc cattggtttg
    21841 agaccgtgcg attttacaat acgagcgagg tcattggcgt aggcaataaa tttttcatag
    21901 ccttttacag ggtagccttc gtttggatag tatttatcag cttgaagcac actccaacct
    21961 ttagcatctg tcgcatcatt ggcatattca tcaagtccga tgttgaagat ttcagtcttt
    22021 ttcgcgaaat aagcagcata cttgtcgata agggcttttg taaaagcgac agcttgttcg
    22081 ttgtcaagat cgacagtacg ggctgatttc ttcccaaaat agctaaagtt agggttttgg
    22141 attcccaatt ctttcatggc attgagaatc gcatccatgt gtccaggact atttactgtc
    22201 ggaatgagac cgataccttt atctttggca tagttaatca gatctgtcat ttgactttct
    22261 gttaagtgat tgccgtttgg atcgttgtaa taatcatttg tacctttttc aatggcgcgt
    22321 ttgacatcgt cactggcata ggtcttgccg ttagctgtga tgctcatatc gtccaacatg
    22381 aaacggagtc catcatttcc gactaatagg tgtaaatcag tgtagccata atgtttcgct
    22441 ttatcgatga tttccttgag ttgttctggt gagaaatatt tacgtccagc atcaatagaa
    22501 acaattttct ttttcgctag tttttcattt acagttgcag cacgttcctt tcctgcctct
    22561 gtttccggtt tgtcagcctc tgctttcgct tcatcttttt tagctggttt atccttgtca
    22621 gtcttgtctg tatttgactc tttagaatca acctctttcg cttcttcctt tttagggcta
    22681 gcttcttctg cctttttatt agcagtttct ttttcagcag aagttggagt taccacttct
    22741 gctttatcac taggagttga actaacttcc tcttgtggtt tttcttctgt ttttggaaga
    22801 ctagctacct tatcagtagc tggagtttct gtttctacag tttttggagc ttctggttga
    22861 agcactgctt taggtgtttc ctcagtccga ttttcggatg attgagggga atcagaaacc
    22921 gtatggatgg tcggttggtt ttctgtagta gtaggagtaa ctccatcggc tgcaacagtc
    22981 tgtgcttgga aggcaaatcc aattagaaca gaagctgctc ctacagcgta tttacgaata
    23041 gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc ctgattgcat tgttatattg
    23101 atagcgatta tataaatcaa cgcctttatt ttatttctta tattaacgag agtcaagagg
    23161 agatgacaaa aaactataat aagtataaaa aaatataaaa tttaaactta agatttcaga
    23221 ttggtcggaa aaaatacgta tatatatcta gtataatttt tggttctatt tctataaaat
    23281 attccacaaa ttatagaatt ttccaaaaat aggtaagcgc tacctttttg gtgtggtata
    23341 ataagcatag aaaaagccca agcgattagc tcaggctttc ttcttagtga tcacggtcac
    23401 atgagataaa tttaatcttg tagtaatcag atcgtttgta agtttcactg tattctaaaa
    23461 cttggccagt tgattcgagt ttggtgattt tagtttgtag gacagtaggg aattgttcat
    23521 cgactccgag gactgaagcc gcatgttctg gagttggaaa gactatttcg ttgatttctt
    23581 caaagtgttc atcattcatg tgaatgtggt agtctaactt gaaacgatta tagatagaac
    23641 tatagtattc aaggtttgga taatttgcgt tgatatattg ttctgggatg taggatgtat
    23701 ggtagatata aacgacaccg tttgattcgc ggatacgttc aatcttgtag tagaattgat
    23761 cgccacgtag acccaatttt tccaagtaaa caagcttgtt tccgcgttca attgaaagaa
    23821 cagttacctt atcatcttta gcattgaaga gttcaatatc tgaaaactct acaagcttgt
    23881 gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg gcggacaata tagccatctt
    23941 tggcaaggtc gtttaaggcg cgaacaactg tgatagagct gacatcgtac attgaaatga
    24001 gttctgcttc agtgtaaaat ttatctccac tgctaaactg cccagagatg attttatttt
    24061 ttaattcgtc ttttatgtat tgatatttgg gaattgccat atttttacct ctattttcct
    24121 tctccataga aaattttacc ataaaagcga aaaaaatagt agtcttttga ataaaaaatt
    24181 agaataatag tctgaaaaat taagcgatat agggattgct catattttat caatgtattc
    24241 tatacaaaat tattttaggt cctatattcc gaatttaaag agcgtttgaa atgggtctaa
    24301 aaatgtttga aactaattga atgtgtgtat aatagtaaaa atgcagtaaa tatcccgaca
    24361 atttctattg acaattcaaa cagattggtt tataattaat ataacaacaa atgaaagcgc
    24421 aaactttcgc ggtcggaagg tagttttatg acacgatttg agatacgaga tgatttctat
    24481 ctcgatggaa aatcatttaa gattttatct ggtgccattc attattttag ggttcctcca
    24541 gaggattggt atcattcgct ctataacttg aaggctcttg gttttaatac ggtagagact
    24601 tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt ttcattttga aggtgatctg
    24661 gatttagaga aatttctcca aatagcgcag gatttgggtc tctacgcaat tgtgcgtccg
    24721 tctccattta tctgtgcgga atgggaattc ggtggcttac cagcttggct cttgaccaag
    24781 aacatgcgaa ttcgctcatc cgacccagca tatatcgagg cagttggtcg ctactatgat
    24841 cagttattgc caagactggt gcctcgtttg ttggacaatg gtggcaatat tctcatgatg
    24901 caggttgaaa atgagtatgg ttcttacgga gaagataagg cttacctgag agcgattcga
    24961 cagctaatgg aagagtgtgg cgtaacctgt cccctcttta catcagatgg tccatggcga
    25021 gctactctga aagctggaac cttaattgaa gaggacctct ttgtaacagg aaactttggt
    25081 tctaaggcac cttacaactt ttcgcagatg caggaattct ttgatgaaca tggtaagaaa
    25141 tggccactca tgtgtatgga gttctgggat ggttggttca atcgctggaa agaaccgatt
    25201 atcacacggg atcctaagga attggcagat gcagttcgag aggttttgga acaaggctct
    25261 atcaatcttt acatgttcca cggtggtaca aactttggtt tcatgaatgg ttgctcagct
    25321 cgaggaactt tggacctgcc acaagttacg tcttatgatt acgatgccct tctggatgaa
    25381 gaaggaaatc caactgctaa atatcttgca gtcaagaaga tgatggcaac acatttttca
    25441 gagtatccgc agttggaacc actctacaaa gagagtatgg agttggatgc tattccacta
    25501 gttgaaaaag tttctttgtt tgaaacctta gatagcttgt caagtcctgt agaaagtctc
    25561 tatcctcaaa agatggagga gctgggacaa agttatggct acctacttta tcgaacagaa
    25621 acaaactggg atgcagaaga agaaagactt cgtatcattg atggtcgaga tagggcccag
    25681 ctgtatgtcg atggtcagtg ggttaaaact caatatcaga cagagattgg ggaagatatt
    25741 ttttatcaag gtaaaaagaa agggctatct aggttagata tcttgataga aaatatgggg
    25801 cgtgtcaact atgggcataa gttcttagcg gatacgcaac gtaagggaat tcggacaggg
    25861 gtctgtaagg atctgcattt cttactaaac tggaaacact atccactccc actagacaat
    25921 cctgagaaaa ttgatttttc aaaaggatgg actcaaggac aaccagcctt ttacgcttat
    25981 gactttacag tcgaagagcc aaaagatact tacctagact tgtctgagtt tggtaagggg
    26041 gttgcctttg tcaatgggca gaatctagga cgtttttgga acgttggccc aactctctca
    26101 ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc gcatcattat ctttgaaaca
    26161 gaaggtcaat ataaagaaga gattcattta actcgtaaac ctacactaaa acatataaag
    26221 ggggaaaact tatgacaatt gtaggatgcc gtattgatgg acgtttgatc cacggacaag
    26281 tagccaatct ttgggctgga aaactaaatg tttcacgcat tatggttgta gacgacgaag
    26341 ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc gacaccacca ggtgtgaaat
    26401 tgagtatttt gccagttgag aaagctgcag ccaatattct tgctggcaaa tacgatagcc
    26461 aacgtctctt tatcgtggct cgtaaaccag accgcttcct tggtttggta gaagcaggtg
    26521 taccacttga aacccttaat gttgggaata tgtctcaaac accagaaact cgttctatta
    26581 cacgttctat caacgtagta gacaaggatg tggaagactt ccacaaactg gcagaaaaag
    26641 gtgttaaact tactgctcag atggttccaa atgatccaat ttcagacttt ttgagcttat
    26701 taaaatagga aaaaaatttt taggaggtca ttgttatgat acaatggtgg caaattttac
    26761 ttctcacttt gtactcagct tatcaaatct gtgatgagtt gacgatcgtt tcatctgcag
    26821 gttcccctgt atttgctggt ttcattactg gtttaatcat gggagatgtg actactggtt
    26881 tacttatcgg tggtaacttg caactgttcg ttcttggggt tggtaccttc ggtggtgctt
    26941 ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc cttctctgtt tcacaaggaa
    27001 ttgatgcacc gcttgccatt actacaatcg ctgtaccagt agcagctctc ttgacttact
    27061 tcgacgttct tggtcgtatg actactacct tcttcgctca ccgtgtggat gctgcaatcg
    27121 aacgctttga ctataaaggt attgaacgca actacttgct tggtgcgatt ccgtgggctc
    27181 tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg tggtgccttt gtacaatcag
    27241 tagtagactt cgttgaagcc tacaaatggg ttgcagatgg cttgacactt gcaggacgta
    27301 tgcttccagg tcttggattt gcaatcttgc ttcgttacct tccagttaaa cgtaaccttc
    27361 actaccttgc tatgggattt ggtttgacag ctatgttgac tgttctttac tcatatgtaa
    27421 caggtcttgg tggcgctgtt gctggtatcg taggtactct tcctgctgaa gttgctgaaa
    27481 aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat tggtatttct atcgtaggta
    27541 ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt agctgtagca gcaccttcta
    27601 caccatcaga aagtggggaa atcgaagatg acgaattcta attacaaact tacaaaagaa
    27661 gattttaatc aaatcaacaa acgtagcttg tttactttcc aattaggttg gaactacgaa
    27721 cgtatgcaag cttctggtta cctttacatg atcttgcctc agttgcgtaa aatgtatggt
    27781 gatggaactc ctgaattgaa agaaatgatg aaagttcata ctcaattctt caatacttca
    27841 ccattcttcc ataccattat cgctggtttt gaccttgcca tggaagaaaa agatggtgta
    27901 ggttcaaaag acgccgttaa cggtatcaag acaggtttga tgggaccatt cgctcctctt
    27961 ggggatacaa tctttggttc acttgtacct gctatcatgg ggtcagtcgc agcaactatg
    28021 gctatcgctg gccaaccttg ggggatcttc ctttggattg cagttgcagt agcgtatgac
    28081 atcttccgtt ggaaacagtt ggaatttgct tacaaagaag gggttaacct tatcaacaac
    28141 atgcaaagta ccttgacagc tttgattgac gctgcatctg tacttggtgt cttcatgatg
    28201 ggtgctcttg tagcaacagt gattaacttt gaaatttctt acaagttgcc aatcggtgaa
    28261 aagatgattg atttccaaga catcttgaac caaatcttcc cacgtttgct tccagcaatc
    28321 tttactgcct ttatcttctg gttgcttggt aagaaaggta tgaactctac taaagctatc
    28381 ggtattatta tcgtacttgc tttggctctt tctgcccttg gtcactttgc acttggaatg
    28441 taattcctta tgactaaatc attaattttg gtgagccatg gtcgcttctg tgaggagctt
    28501 agaggtagca cagaaatgat tatgggccca caagacaaca tttacacagt agctcttctt
    28561 ccagaagatg gcccagaaga atttactgct aaatttgaag ctgttattga aggattggat
    28621 gatttcctag tctttgcgga tcttctcggt gggacacctt gtaatgtggt gagtcgcttg
    28681 atcatggaag gtcgtgatat tgacctttac gcagggatga atcttccaat ggtgattgaa
    28741 tttatcaatg cgagccttac aggcgcagat gcggactaca agagccgtgc tgcagaaagc
    28801 attgtgaaag ttaatgacct gttagcgggc ttcgatgatg acgaagatga ataatactct
    28861 tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt aggtatatgt tactgacttc
    28921 gtcagtctta tccggcaacc tcaaaacggt gttttgagct gacttcgtca gtcttatccg
    28981 gcaacctcaa agcagtgctt tgagcagcct gcggctagtt tcctacagat tttagttgga
    29041 actcgattca attcatgtga caacgtgaaa atcgttagag cattttatat agaatataca
    29101 tgggaatgta gcttactccc attcccatat ttaatagaaa aagaggaact aaatgctaca
    29161 ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc actacgcgtg aaatctacca
    29221 acagcctgat gtatggagag aagcttttga attttatcaa gcaaaacgtg aagaaattgc
    29281 agccttccta caagaaatcg ctgataaaca tgactatatt aaggttatct tgacaggtgc
    29341 tgggacttct gcttatgtgg gagatacctt gctaccttat tttaaggaag tctatgacga
    29401 acgcaaatgg aatttcaatg ctattgcgac aacagatatc gttgccaatc cagcaaccta
    29461 tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct cgtagtggga attcgcctga
    29521 aagtttggcg actgttgatt tggccaaatc cttggtggat gagctttatc aagtgacgat
    29581 tacttgtgca gcagatggta aattggctct tcaagctcac ggtgatgatc gtaatctctt
    29641 gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc atgacttcta gctttacgtc
    29701 tatgatgttg acaactctct tggtctttga tcctacagaa tttgctgtta agtctgaacg
    29761 ttttgaagtt gtatctagtc ttgcccgtaa agttttagac aaggcagaag atgtcaaaga
    29821 gctcgttgat ttagacttta accgtgtcat ctatctaggc gctggtcctt tctttggact
    29881 tgctcatgaa gctcagctca agattttgga attaactgct ggtcaagttg cgaccatgta
    29941 tgaaagccca gttggcttcc gtcacggtcc aaaatctctt atcaacgaca atacagttgt
    30001 tttggtcttt ggtacaacga cagactacac tcgtaagtac gacttggact tggttcgtga
    30061 agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg agtgatcaag cttttggtct
    30121 tgaaaatgtc aaagaagtgg cccttggttg tggcggtgtc ttgaatgata tttaccgtgt
    30181 cttcccttac atcgtttatg cccaactctt tgctttattg acttcactca aggtagaaaa
    30241 taaaccagat acaccgtctc ctacaggtac agtaaaccgt gtagtacaag gtgtcataat
    30301 tcacgaatat caaaagtaag acagtgttta tgaattcttg acaagaggat ttgtaaatta
    30361 tcagataaac catagattgt cagtacgctt tctatggttt gtttgcttga gagaaatagt
    30421 aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt tggaaatgtt gagggtgagg
    30481 atgtcttggc ctatcgattt gagacagacg gtggctacca acttgaggtt atgacttatg
    30541 gtgcgactat cttgcgctat gtcgcacctg acaaggctgg aaattttgcc aatgttatct
    30601 tgggatttga tgactttgat agttatgtag gcaatagtcc caagcatgga gcaagtgtag
    30661 gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct caatggtaag acctatgacc
    30721 ttgaggttaa taatgctagc aactgtaatc acagtggttc aactggttgg gattccagct
    30781 tgtttgaagt tgaagaagta agcgatcatg gcttgactct ctacacagag cgtacagatg
    30841 ggacaggagg gttccctgga aatctcaaga tttggatcag ttatcacttg gaagaaactg
    30901 gtgcctatga aatcagctac aaggtaacga ccgatcagga tacgctggtc aatccaacca
    30961 accacagcta tttcaacttg tctggtgatt tcacgcagac gattgaccgt catgtcttcc
    31021 aactaaacac agagggcatt tactcaatcg ctcctgacgg tgttcctgcc aaaactccag
    31081 aagccaaccg tgatgtggtc aaacacgtct acaatggtac cttgttgaag gatatctttg
    31141 cagaagaaga tgagcaaatc cagctggcat caggtttgga tcatccattt gcccttcctg
    31201 caggccatga caatgctgga ttcctttatg accaaaattc aggtcgcttc ctgcttttca
    31261 agacagaagc tccttgcttt gtggtctaca cagcaaactt tgtggatgaa agtgtcatca
    31321 taggaggtca gccaatgcta cagcacaatg ggattgctct tgaagcgcaa gctttaccag
    31381 atgccattca cagtgacctt aaaggccaag tcattcttaa agctggtcaa accttcacca
    31441 gtaagacacg ttatgaactt gttgtgaagt aaaagagtca ttgcgcctac ttttgggagc
    31501 taggaatagg tacgcagaga caaatagtag gaaaatatga tataactaag cgttgaaagc
    31561 tatctgttaa tataatattc aaactacaat aaggagtaag aaagaaacga agaaaattgt
    31621 atttgctagt gccttggctt tgaccttggc tggagcagtt ttgacaaatg atgtttttgc
    31681 gaacgacaga cttgtggcaa cacaaactac tgatggtaaa aatgaaaatg tattgacctc
    31741 agaggtgcta aaaccttcta gtggcaatgt tttggttgga atcaaaggag aatttgtggc
    31801 tcctcatcaa caatctattt tggatgccat caatgctatc tgtaaagaag cggctgacga
    31861 aggtttggta gataagtatg tccctatcaa atggtcaact gacctagaaa aggcagcttt
    31921 tgccagagct acagaagcat ctataaccat ggatcatacc cgtctttcta gcaaagatct
    31981 ttggagtgcc tttccaactt ctaatagtat aatgggagaa aatttggcat ggaatcatga
    32041 cggttttcta aaagctattg aacaatggcg tgctgaaaaa gcagattatg tggagacaaa
    32101 aatagtggtt cagacaacgg gaaatctggt cactatgagt cgctaattaa ccctaaattt
    32161 acacacatgg ggatggcagc ttttaaaaat cctaacaatc aatacaaagc tattacaatt
    32221 gctcaaactc taggtgatga tgcttcttca gaggaattgg ctggtagata tggttctgct
    32281 gttcagtgta cagaagtgac tgcctcaaac ctttcaacag ttaaaactaa agctacggtt
    32341 gtagaaaaac cactgaaaga ttttagagcg tctacgtctg atcagtctgg ttgggtggaa
    32401 tctaatggta aatggtattt ctatgagtct ggtgatgtga agacaggttg ggtgaaaaca
    32461 gatggtaaat ggtactattt gaatgactta ggtgtcatgc agactggatt tgtaaaattt
    32521 tctggtagct ggtattactt gagcaattca ggtgctatgt ttacaggctg gggaacagat
    32581 ggtagcagat ggttctactt tgacggctca ggagctatga agacaggctg gtacaaggaa
    32641 aatggcactt ggtattacct tgacgaagca ggtatcatga agacaggttg gtttaaagtc
    32701 ggaccacact ggtactatgc ctacggttca ggagctttgg ctgtgagcac aacaacacca
    32761 gatggttacc gtgtaaatgg taatggtgaa tgggtaaact aggctcaggc cataggtaaa
    32821 gcattcatct tacttagcaa aaagaatgaa cgataagaaa gaggttgatg gcgaacattg
    32881 gcctcttttg atttataaag attggattct tgtcgcctca atttcagact tttctattgt
    32941 aagctaatat tttatagccc attaaaagca taagcggtaa tctaatttaa aaaatgctgt
    33001 aattagtctg aagtccacac ttacttgttg agatgttatc tctgtttttt atcgttataa
    33061 tttactgtat tttttatagt atgcagaata tttttaagta tatttcaata gaaatttcta
    33121 tcgatttatt gtataatgat aagtaattgt tgaaaagtac tcagaaaatt ccatactata
    33181 ttatttttat gtttatactt ttatgctata aaatatagat tgatataaag aatatagaaa
    33241 aagcgaggtt aatatgagcc gaaaaagcat tggtgagaaa cgccatagtt tctcgatgag
    33301 aaagttgtca gtgggattgg tatcagttac tgtatctagt ttctttttga tgagtcaagg
    33361 gattcaatcg gtatcggccg ataatatgga aagtccaatt cattataagt atatgaccga
    33421 gggtaaattg acagacgagg aaaaatcctt gctggtagag gcccttccac aactggctga
    33481 agaatcagat gatacttatt acttggttta tagatctcaa cagtttttac cgaatacagg
    33541 ttttaaccca actgttggta ctttcctttt tactgcagga ttgagcttgt tagttttatt
    33601 ggtttctaaa agggaaaatg gaaagaaacg acttgttcat tttctgctgt tgactagcat
    33661 gggagttcaa ttgttgccgg ccagtgcttt tgggttgacc agccagattt tatctgccta
    33721 taatagtcag ctttctatcg gagtcgggga acatttacca gagcctctga aaatcgaagg
    33781 ttatcaatat attggttata tcaaaactaa gaaacaggat aatacagagc tttcaaggac
    33841 agttgatggg aaatactctg ctcaaagaga tagtcaacca aactctacaa aaacatcaga
    33901 tgtagttcat tcagctgatt tagaatggaa ccaaggacag gggaaggtta gtttacaagg
    33961 tgaagcatca ggggatgatg gactttcaga aaaatcttct atagcagcag acaatctatc
    34021 ttctaatgat tcattcgcaa gtcaagttga gcagaatccg gatcacaaag gagaatctgt
    34081 agttcgacca acagtgccag aacaaggaaa tcctgtgtct gctacaacgg tgcagagtgc
    34141 ggaagaggaa gtattggcga cgacaaatga tcgaccagag tataaacttc cattggaaac
    34201 caaaggcacg caagaacccg gtcatgaggg tgaagccgca gtccgtgaag acttaccagt
    34261 ctacactaag ccactagaaa ccaaaggtac acaaggaccc ggacatgaag gtgaagctgc
    34321 agttcgcgag gaagaaccag cttacacaga accgttagca acgaaaggca cgcaagagcc
    34381 aggtcatgag ggcaaagcta cagtccgcga agagactcta gagtacacgg aaccggtagc
    34441 gacaaaaggc acacaagaac ccgaacatga gggcgaagcg gcagtagaag aagaacttcc
    34501 ggctttagag gtcactacac gaaatagaac ggaaatccag aatattcctt atacaacaga
    34561 agaaattcag gatccaacac ttctgaaaaa tcgtcgtaag attgaacgac aagggcaagc
    34621 agggacacgt acaattcaat atgaagacta catcgtaaat ggtaatgtcg tagaaactaa
    34681 agaagtgtca cgaactgaag tagctccggt caacgaagtc gttaaagtag gaacacttgt
    34741 gaaagttaaa cctacagtag aaattacaaa cttaacaaaa gttgagaaca aaaaatctat
    34801 aactgtaagt tataacttaa tagacactac ctcagcatat gtttctgcaa aaacgcaagt
    34861 tttccatgga gacaagctag ttaaagaggt ggatatagaa aatcctgcca aagagcaagt
    34921 aatatcaggt ttagattact acacaccgta tacagttaaa acacacctaa cttataattt
    34981 gggtgaaaat aatgaggaaa atactgaaac atcaactcaa gatttccaat tagagtataa
    35041 gaaaatagag attaaagata ttgattcagt agaattatac ggtaaagaaa atgatcgtta
    35101 tcgtagatat ttaagtctaa gtgaagcgcc gactgatacg gctaaatact ttgtaaaagt
    35161 gaaatcagat cgcttcaaag aaatgtacct acctgtaaaa tctattacag aaaatacgga
    35221 tggaacgtat aaagtgacgg tagccgttga tcaacttgtc gaagaaggta cagacggtta
    35281 caaagatgat tacacattta ctgtagctaa atctaaagca gagcaaccag gagtttacac
    35341 atcctttaaa cagctggtaa cagccatgca aagcaatctg tctggtgtct atacattggc
    35401 ttcagatatg accgcagatg aggtgagctt aggcgataag cagacaagtt atctcacagg
    35461 tgcatttaca gggagcttga tcggttctga tggaacaaaa tcgtatgcca tttatgattt
    35521 gaaaaaacca ttatttgata cattaaatgg tgctacagtt agagatttgg atattaaaac
    35581 tgtttctgct gatagtaaag aaaatgtcgc agcgctggcg aaggcagcga atagcgcgaa
    35641 tattaataat gttgcagtag aaggaaaaat ctcaggtgcg aaatctgttg cgggattagt
    35701 agcgagcgca acaaatacag tgatagaaaa cagctcgttt acagggaaac ttatcgcaaa
    35761 tcaccaggac agtaataaaa atgatactgg aggaatagta ggtaatataa caggaaatag
    35821 ttcgagagtt aataaagtta gggtagatgc cttaatctct actaatgcac gcaataataa
    35881 ccaaacagct ggagggatag taggtagatt agaaaatggt gcattgatat ctaattcggt
    35941 tgctactgga gaaatacgaa atggtcaagg atattctaga gtcggaggaa tagtaggatc
    36001 tacgtggcaa aacggtcgag taaataatgt tgtgagtaac gtagatgttg gagatggtta
    36061 tgttatcacc ggtgatcaat acgcagcagc agatgtgaaa aatgcaagta catcagttga
    36121 taatagaaaa gcagacagat tcgctacaaa attatcaaaa gaccaaatag acgcgaaagt
    36181 tgctgattat ggaatcacag taactcttga tgatactggg caagatttaa aacgtaatct
    36241 aagagaagtt gattatacaa gactaaataa agcagaagct gaaagaaaag tagcttatag
    36301 caacatagaa aaactgatgc cattctacaa taaagaccta gtagttcact atggtaacaa
    36361 agtagcgaca acagataaac tttacactac agaattgtta gatgttgtgc cgatgaaaga
    36421 tgatgaagta gtaacggata ttaataataa gaaaaattca ataaataaag ttatgttaca
    36481 tttcaaagat aatacagtag aatacctaga tgtaacattc aaagaaaact tcataaacag
    36541 tcaagtaatc gaatacaatg ttacaggaaa agaatatata ttcacaccag aagcatttgt
    36601 ttcagactat acagcgataa cgaataacgt actaagcgac ttgcaaaatg taacacttaa
    36661 ctcagaagct actaaaaaag tactaggagc agcgaatgat gcagccttag ataacctata
    36721 cttagataga caatttgaag aagttaaagc taatatagca gaacacctaa gaaaagtatt
    36781 agcgatggat aaatcaatca atactacagg agacggtgta gttgaatacg taagtgagaa
    36841 aatcaaaaat aacaaagaag catttatgct aggtcttact tatatgaacc gttggtacga
    36901 tattaattat ggtaaaatga atacaaaaga tttatctacg tacaagtttg actttaacgg
    36961 aaataatgag acttcaacgt tggatactat tgtcgcatta ggaaatagtg gactagataa
    37021 cctgagagct tcaaatactg taggtttata tgcgaataaa cttgcatcgg taaaaggaga
    37081 agattcagtc tttgacttcg tagaagcgta tagaaaactg ttcttaccaa acaaaacaaa
    37141 taacgagtgg tttaaagaaa atacaaaggc atatatagtc gaaatgaagt ctgatattgc
    37201 agaagtacga gaaaaacaag aatcaccaac agccgataga aaatattcat taggagttta
    37261 cgatagaata tcagcaccaa gttgggggca taagagtatg ttattaccac tactaacttt
    37321 acctgaagaa tctgtgtata tttcatcgaa tatgtctaca cttgcattcg gttcgtatga
    37381 aagatatcgt gatagtgtgg atggagttat tctttcagga gatgctttac gaacttatgt
    37441 aagaaataga gttgatatag cagcgaaaag gcatagagac cattatgata tttggtacaa
    37501 tcttcttgac agtgcttcaa aagaaaaact tttccgttct gtgatagttt atgatggatt
    37561 caatgtaaaa gatgagacag gaagaactta ttgggcaagg ttaacggata aaaacatcgg
    37621 ctctattaaa gaattcttcg gacctgttgg gaaatggtat gagtataata gtagtgcagg
    37681 agcgtatgcg aatggaagtt taacgcactt tgtgttagat agattattag atgcttatgg
    37741 aacgtcggtt tatactcatg aaatggttca taattctgat tctgcaatct actttgaagg
    37801 aaatggtaga cgtgaaggat tgggagcgga gttatacgca cttggtttac tgcaatctgt
    37861 agatagtgta aattctcata ttttagcttt aaatacgtta tataaagcag aaaaagatga
    37921 tttgaataga ttgcatacat ataatccggt ggaacgtttc gattcggatg aggcgcttca
    37981 aagttatatg catggatcat atgatgtaat gtatacactt gatgcgatgg aagcaaaagc
    38041 gatattagct caaaataatg atgttaagaa aaaatggttt agaaaaatag aaaattatta
    38101 cgttcgtgat actagacata ataaagatac acatgcagga aataaagtcc gtccattaac
    38161 agatgaagaa gtagctaact taacatcgtt aaactcatta atcgacaacg acatcataaa
    38221 tagacgtagc tatgatgata atagagaata taaacgaaat ggctactata ctataagtat
    38281 gttctctcct gtatacgcag cgctaagcaa ttcgaaaggt gctcctggag atattatgtt
    38341 tagaaaaata gcttatgaat tacttgcgga aaaaggttat cacaaaggat tcctacctta
    38401 tgtttctaat cagtacggag cagaagcatt tgccagcgga agcaaaacat tctcatcatg
    38461 gcatggaaga gatgttgctt tagtgacaga tgatttagta tttaagaaag tattcaatgg
    38521 tgagtactca tcatgggctg atttcaaaaa agcaatgttt aaacaacgta tagataaaca
    38581 agataatctg aaaccaataa caattcaata cgaattaggt aatcctaata gtacaaaaga
    38641 agtaactata acaacggctg cacaaatgca acaattaatt aatgaagcgg ctgcgaaaga
    38701 tattactaat atagatcgtg caacgagtca taccccagca agttgggtgc atttattaaa
    38761 acaaaaaatc tataatgcat atcttcgcac tacagatgac tttagaaatt ctatatataa
    38821 ataagattgt agagtttcat tgttgagtag tgtttcttgt aaggatgagg agtcagatga
    38881 caaatcgact cctttttctt atggatcgat gtagagattt gattgaatgc agattgcagg
    38941 aatcatcttc aactcatcaa cgaccaatgg tgacaaggtg gatttcaatc ccacagaaaa
    39001 tgttgatttg agaaataact ttgctagtct agtaaaataa atacaaaaca atcctagaag
    39061 attttttctg ggattgtttt ttgctgagtg ggatgcttca agttgtctgg cttgactttc
    39121 ttgagggaag ttatataata gttgtaataa ttaaagttac aataaaagag gaaatattta
    39181 tgacatatga ataccagagc cacatttatt tagcagaggc agttttaaat gtgaaggatt
    39241 tggtcagtca aacagttttt tatcagcaga ttattggttt agaaatccta tctcaaacgg
    39301 atacagaggt cgttctggga cttggaggaa aagccttggt acacttgatt caagcacaag
    39361 agggtggaga agtaagggaa cattatggtc tttaccatct ggctattctt ttgccgacac
    39421 gaaaggcttt ggcggatgtc ttgaagcacc tgacggattt acagattcct cttgttggcg
    39481 gtgcagatca cggttacagt gaggcccttt acttagagga cttggaggga aatggcattg
    39541 aactctatcg agataagcca gtttccacat gggatattcg agaagatgga cgtattatcg
    39601 gggtgactga agtccttgcg gctcaggata tctatgagtt gggggaaaga gtagagcctt
    39661 ttatcctagc agagggtacg agaatggggc atattcatct ttctgtcaag gatagtcgaa
    39721 agtccagaca gttttatcaa acggtgttag ggctcgagga taaattcagt gtgcctagtg
    39781 ctagttggat cgcagctggg gactaccatc atcatttagc agtcaacgaa tggggaggaa
    39841 aaggtctgga tccgcgtaaa caagtcctac caggtttagc ctactatgtc atcgaagtcg
    39901 cacataaaga agaactgtta acgattgccc aacgagcaca agaagttgac gcaccaatca
    39961 aatggatgac atcgatccaa ttggaaatca cagactcaga tggcatcgtg acccgtattc
    40021 gtttagctag atagatggta tgtgatgaag gtagagcatc aattgtagaa agtgctcctt
    40081 attctagtca gatacgtgga aaatttgata tgatagtagg gaataaggag aagaataata
    40141 tgactagcga ataccagaaa atgatagcag gagagtttta ccgtccatca gacccagaac
    40201 tgagagcctt agctcaggct tctcgccaaa aacaggccgc ctttaacaag gaagagaacc
    40261 ccttgaaggg agccgaaatc atcaagactt ggtttgcctc aaccgggaaa aatctttaca
    40321 tcaacactcg cttgatggtg gactacggtg tcaacatcca tctaggggaa aatttttatt
    40381 ctaattggaa cttgaccatg ctggatatct gtcccattcg tatcggggac aatgctatga
    40441 ttggtcctaa ttgtcagttt ttgacacccc tccatccact agatccacag gaacgcaatt
    40501 caggtatcga gtacggaaag cctatcacaa tcggagataa tttctggact ggtggtggcg
    40561 tcattgtcct tcctggagtg acactgggaa ataatgtcgt tgcaggagca ggggcagtaa
    40621 ttaccaaatc ttttggcgac aacgttgtcc tagctggcaa tcctgcgcgc gtgattaagg
    40681 aaatacctgt taaatagaag taaaaaggaa cagctggggt tgtttctttt ttgtaggttt
    40741 catcattttt tacccagttc acatttacct actctatctc ttagcaagtc tgtttcatta
    40801 agcaagttca aagcatctcg taagtgggat gtttttctcc tcagttcatc agcttcctcc
    40861 ttgacactcg gtcagatttt gatacaatag tacaaaatta gaggaggcag gctatgattc
    40921 agaaacatgc gattcctatt ttagagtttg atgacaatcc tcaggcggtt atcatgccca
    40981 atcacgaggg gctggacttg cagttgccaa agaagtgtgt ttatgcattt ttaggtgagg
    41041 agattgaccg ctatgcgagg gaagtagggg cgaactgtgt tggcgaattt gtttctgcca
    41101 ccaagaccta tccagtttat gtcgtgaact acaaggacga ggagatttgt ctggttcagg
    41161 ctcctgtcgg ttcagctcca gcagcccagt ttatggattg gttgattggc tatggtgtgg
    41221 agcagattat ctctactggg acctgtggtg tcctagctga tatagaggaa aatgcctttc
    41281 tagtccctgt tcgcgctctg cgagatgaag gagccagtta ccactatgtg gcaccttctc
    41341 gttatatgga aatgcagcca gaggctattg ctgccattga gcgagttttg gatgatagag
    41401 ggattcctta tgaagaagtc atgacctggt ccacagatgg tttttaccga gaaacggctg
    41461 aaaaggtggc ttatcgcaag gaagaagact gtgctgttgt ggagatggag tgttccgctc
    41521 ttgcggcagt agctcaattg cgtggggttc tctggggtga attgttgttc acagcagatt
    41581 ctctagcgga cttggaccag tacgacagtc gtgactgggg ctcggaagct tttaataagg
    41641 cgctagaact gagtttagca agtgttcacc acctttagtt gtactggcaa aggatttgtt
    41701 ttatcataaa atgtctagct catacttttc aaaaatatgt ttaaacgagg tcaccttcct
    41761 cttgtcctag gcatgttgag gttgggaaaa atctttaaaa tcagaaaaac gtatcatatc
    41821 aggtgatgaa aactttgaca ctatgcgttt tatgtcgata agatttagag tgagatgaaa
    41881 tgatactctt cgaaaatctc ttcaaaccag gtcagcttca ccttgccgta ggtatatgtt
    41941 actgacttcg tcagtcttat ccggcaacct caaaacggtg ttttgagctg acttcgtcag
    42001 ttctatttgc aacctcaaaa cagtgttttg agcaacctgt gactagcttt ctaatcgatg
    42061 ccttggtttt cattgcctat aatcaaaaag agaaattttc tcctgaaaag catatagagt
    42121 agctggcgtt aaaagctcct gtcttgcttt tttgacctat agtcacatat atcaagtatt
    42181 gttcttgcct aagctatcaa taaaaaggtg gcatttttta ggcttggtgt tagtagattt
    42241 tgccttatcc tatctaagtc atttcgaact ttttatggta caatggaaac atgttattca
    42301 aattatctaa ggaaaaaata gagctaggct tatctcgttt atcgccagcc cgtcgtattt
    42361 ttttgagttt tgccttggtc attttactag gctctcttct tttgagcttg ccctttgtcc
    42421 aagttgaaag ctcacgagcg acttattttg atcatctttt cactgctgtc tctgcagtct
    42481 gtgtgacggg tctctcaacc cttccagtag ctcacaccta taatatctgg ggtcaaataa
    42541 tctgtttgct cttgattcag atcggtggtc tagggctcat gacctttatt ggggttttct
    42601 atatccagag caagcaaaag cttagtcttc gtagccgtgc aactattcag gatagtttta
    42661 gttatggaga aactcgatct ttgagaaagt ttgtctattc tatttttctc acgacctttt
    42721 tggttgagag cttgggagct attttgctta gttttcgcct tattcctcaa cttggctggg
    42781 gacgtggtct ttttagttcc atttttctag cgatctcagc cttctgtaat gccggttttg
    42841 ataatttagg gagcaccagt ttatttgctt ttcagaccga tttactggtc aatctggtga
    42901 ttgcaggctt aattattaca ggcggccttg gttttatggt ctggtttgat ttggctggtc
    42961 atgtaggaag aaagaaaaaa ggacgtctgc actttcatac gaagcttgta ctattgttga
    43021 ctataggttt gttgttattt ggaacggcaa ctactctctt tcttgagtgg aacaatgctg
    43081 gaacgattgg caatctccct gttgccgata aggttttagt tagctttttt caaacagtga
    43141 cgatgcgaac agctggcttt tctacgatag attatactca ggctcatcct gtgactcttt
    43201 tgatttatat cttacagatg tttctaggtg gggcacctgg aggaacagct gggggactca
    43261 agattacgac attttttgtc ctcttggtct ttgcacgaag tgagcttcta ggcttgcctc
    43321 atgccaatgt tgcgagacga acgattgcgc cgcgaacggt tcaaaaatcc tttagtgtct
    43381 ttattatctt tttgatgagc ttcttaatag gattgattct gctagggata acagccaaag
    43441 gcaatcctcc ctttatccac ctcatatttg aaaccatttc agctcttagt acagttggtg
    43501 taacggcaaa tctgactcct gaccttggga aattggctct cagtgttatc atgccactta
    43561 tgtttatggg acgaattggt cccttgacct tgtttgttag cttggcagat taccatccag
    43621 aaaagaaaga tatgattcac tatatgaaag cagatattag tattggttaa gaaaggaaag
    43681 agcatgtcag atcgtacgat tggaattttg ggcttgggaa tttttgggag cagtgtccta
    43741 gctgccctag ccaagcagga tatgaatatt atcgctattg atgaccacgc agagcgcatc
    43801 aatcagtttg agccagtttt ggcgcgtgga gtgattggtg acatcacaga tgaagaatta
    43861 ttgagatcag cagggattga tacctgcgat accgttgtag tcgcgacagg tgaaaatctg
    43921 gagtcgagtg tgcttgcggt tatgcactgt aagagtttgg gggtaccgac tgttattgct
    43981 aaggtcaaaa gtcagaccgc taagaaagtg ctagaaaaga ttggagctga ctcggttatc
    44041 tcgccagagt atgaaatggg gcagtctcta gcacagacca ttcttttcca taatagtgtt
    44101 gatgtctttc agttggataa aaatgtgtct atcgtggaga tgaaaattcc tcagtcttgg
    44161 gcaggtcaaa gtctgagtaa attagacctc cgtggcaaat acaatctgaa tattttgggt
    44221 ttccgagagc aggaaaattc cccattggat gttgaatttg gaccagatga cctcttgaaa
    44281 gcagatacct atattttggc agtcatcaac aaccagtatt tggataccct agtagcattg
    44341 aattcgtaaa gagggatgac ccctcttttt tgatgcccaa gatggcaaat agagacagaa
    44401 gccccttgtc ttctagtaaa agttcttcaa aggctggact ttatggtaaa atagaaggaa
    44461 gtgacaagag agagtaatac tcaatgaaaa tcaaagatca aactaggaaa ctagctacgg
    44521 gctgcttaaa acactgtttt gaggttgtgg atagaactga cgaagtcagc tcaaaacact
    44581 gttttgaggt tgcagataga actgacgaag tcagtaacat ctatacggca aggcgatgtt
    44641 gacgcggttt gaagagattt tcgaagagta taagaaaaaa tcagtcccct aaaggagcag
    44701 attatgaagt tattgtctat cgccatttct agctataatg cagcagccta tcttcattac
    44761 tgtgtggagt cgctagtgat tggctgggac caggtcggaa atttctccaa aggccagtat
    44821 accatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca gttctaactg
    44881 cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca gcaggtcaag
    44941 accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga ggaccagtct
    45001 gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa tcgactcttg
    45061 gtagaccaac ttgatttgtc ccaagtgagt catcccaaaa tgcgagaata tctgctgaat
    45121 catattgaaa tcacgacggt gatttccagt accctgctca accgatctgg aacagcggag
    45181 catctggcaa aaaaacgcca attgtggacc tatattcagc agaaaaatcc agaagtcttt
    45241 caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt gccagatcgc
    45301 aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa ttaatataag
    45361 tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt ttaatttcag
    45421 gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta tgaaattcaa
    45481 tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg ttgcctcagt
    45541 tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac gtgccgatgt
    45601 ggtcaatccg accccaggtc aagtcttacc tgaagagaca tcgggaacga aagagggtga
    45661 cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg gcgttactgg
    45721 aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg aaacaaactc
    45781 ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caaaaaaatc cagagctaac
    45841 agatgtctta aaagaaactg tagatacagc tgatgtggat gggacacaag caagtccagc
    45901 agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag acagcatcga
    45961 tgttcctgct gcttatcttg aaaaagctga agggaaaggt cctttcactg ccggtgtaaa
    46021 ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc tattactaaa
    46081 agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg ctttacctcc
    46141 tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg gcaatactgt
    46201 tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc aaacttataa
    46261 agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta atctagttgc
    46321 tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaacag ttcaaaaagc
    46381 cgttgcaga
//
LOCUS       DAVHSH010000010        44323 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000010 DAVHSH010000000
VERSION     DAVHSH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44323
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.010"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            516..812
                     /locus_tag="VVR08_000679"
     CDS             516..812
                     /locus_tag="VVR08_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6074633.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
     gene            915..2930
                     /locus_tag="VVR08_000680"
     CDS             915..2930
                     /locus_tag="VVR08_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6074634.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGDDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWHDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAHELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2932..3564
                     /locus_tag="VVR08_000681"
     CDS             2932..3564
                     /locus_tag="VVR08_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074635.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLNLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4495..4908)
                     /gene="ndk"
                     /locus_tag="VVR08_000682"
     CDS             complement(4495..4908)
                     /gene="ndk"
                     /locus_tag="VVR08_000682"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU6074636.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENDIIQNVVHGSDSEESAKREIALWF"
     gene            complement(5019..8696)
                     /gene="rpoC"
                     /locus_tag="VVR08_000683"
     CDS             complement(5019..8696)
                     /gene="rpoC"
                     /locus_tag="VVR08_000683"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU6074637.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     IGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8729..12340)
                     /gene="rpoB"
                     /locus_tag="VVR08_000684"
     CDS             complement(8729..12340)
                     /gene="rpoB"
                     /locus_tag="VVR08_000684"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6074638.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12756..12826
                     /locus_tag="VVR08_000685"
     tRNA            12756..12826
                     /locus_tag="VVR08_000685"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12788..12790,aa:Cys,seq:gca)
     gene            complement(13024..14355)
                     /locus_tag="VVR08_000686"
     CDS             complement(13024..14355)
                     /locus_tag="VVR08_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU6074639.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14634..15458)
                     /gene="endA"
                     /locus_tag="VVR08_000687"
     CDS             complement(14634..15458)
                     /gene="endA"
                     /locus_tag="VVR08_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU6074640.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15497..15685)
                     /locus_tag="VVR08_000688"
     CDS             complement(15497..15685)
                     /locus_tag="VVR08_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6074641.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AVLSPAKWQELIHKFTGN"
     gene            complement(15678..16961)
                     /gene="murA"
                     /locus_tag="VVR08_000689"
     CDS             complement(15678..16961)
                     /gene="murA"
                     /locus_tag="VVR08_000689"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6074642.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16985..17215)
                     /locus_tag="VVR08_000690"
     CDS             complement(16985..17215)
                     /locus_tag="VVR08_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU6074643.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17273..18310)
                     /locus_tag="VVR08_000691"
     CDS             complement(17273..18310)
                     /locus_tag="VVR08_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU6074644.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18294..18782)
                     /gene="coaD"
                     /locus_tag="VVR08_000692"
     CDS             complement(18294..18782)
                     /gene="coaD"
                     /locus_tag="VVR08_000692"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU6074645.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18772..19311)
                     /gene="rsmD"
                     /locus_tag="VVR08_000693"
     CDS             complement(18772..19311)
                     /gene="rsmD"
                     /locus_tag="VVR08_000693"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU6074646.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLIFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19376..20368)
                     /locus_tag="VVR08_000694"
     CDS             complement(19376..20368)
                     /locus_tag="VVR08_000694"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU6074647.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20480..21163)
                     /locus_tag="VVR08_000695"
     CDS             complement(20480..21163)
                     /locus_tag="VVR08_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU6074648.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(21219..21959)
                     /locus_tag="VVR08_000696"
     CDS             complement(21219..21959)
                     /locus_tag="VVR08_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU6074649.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            21993..22271
                     /locus_tag="VVR08_000697"
     CDS             21993..22271
                     /locus_tag="VVR08_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU6074650.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22349..23275
                     /gene="yidC"
                     /locus_tag="VVR08_000698"
     CDS             22349..23275
                     /gene="yidC"
                     /locus_tag="VVR08_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6074651.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23350..24144)
                     /gene="pflA"
                     /locus_tag="VVR08_000699"
     CDS             complement(23350..24144)
                     /gene="pflA"
                     /locus_tag="VVR08_000699"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU6074652.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24270..25520)
                     /locus_tag="VVR08_000700"
     CDS             complement(24270..25520)
                     /locus_tag="VVR08_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU6074653.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25587..26414)
                     /gene="purR"
                     /locus_tag="VVR08_000701"
     CDS             complement(25587..26414)
                     /gene="purR"
                     /locus_tag="VVR08_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU6074654.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26681..27622)
                     /locus_tag="VVR08_000702"
     CDS             complement(26681..27622)
                     /locus_tag="VVR08_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU6074655.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27612..28868)
                     /locus_tag="VVR08_000703"
     CDS             complement(27612..28868)
                     /locus_tag="VVR08_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU6074656.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28870..29532)
                     /locus_tag="VVR08_000704"
     CDS             complement(28870..29532)
                     /locus_tag="VVR08_000704"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU6074657.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29495..30151)
                     /locus_tag="VVR08_000705"
     CDS             complement(29495..30151)
                     /locus_tag="VVR08_000705"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6074658.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(30162..31040)
                     /gene="rsgA"
                     /locus_tag="VVR08_000706"
     CDS             complement(30162..31040)
                     /gene="rsgA"
                     /locus_tag="VVR08_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU6074659.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(31042..31914)
                     /gene="rsmA"
                     /locus_tag="VVR08_000707"
     CDS             complement(31042..31914)
                     /gene="rsmA"
                     /locus_tag="VVR08_000707"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU6074660.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQTGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(32045..32353)
                     /locus_tag="VVR08_000708"
     CDS             complement(32045..32353)
                     /locus_tag="VVR08_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074661.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32346..32987)
                     /locus_tag="VVR08_000709"
     CDS             complement(32346..32987)
                     /locus_tag="VVR08_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074662.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32989..35019)
                     /locus_tag="VVR08_000710"
     CDS             complement(32989..35019)
                     /locus_tag="VVR08_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6074663.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35096..35392)
                     /locus_tag="VVR08_000711"
     CDS             complement(35096..35392)
                     /locus_tag="VVR08_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6074664.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35712..36623)
                     /locus_tag="VVR08_000712"
     CDS             complement(35712..36623)
                     /locus_tag="VVR08_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6074665.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(36695..37255)
                     /gene="rnmV"
                     /locus_tag="VVR08_000713"
     CDS             complement(36695..37255)
                     /gene="rnmV"
                     /locus_tag="VVR08_000713"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU6074666.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37255..38028)
                     /locus_tag="VVR08_000714"
     CDS             complement(37255..38028)
                     /locus_tag="VVR08_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU6074667.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELLLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38333..38998)
                     /locus_tag="VVR08_000715"
     CDS             complement(38333..38998)
                     /locus_tag="VVR08_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU6074668.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            complement(39261..39395)
                     /gene="rpmH"
                     /locus_tag="VVR08_000716"
     CDS             complement(39261..39395)
                     /gene="rpmH"
                     /locus_tag="VVR08_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU6074669.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39540..40754)
                     /locus_tag="VVR08_000717"
     CDS             complement(39540..40754)
                     /locus_tag="VVR08_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6074670.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKKLLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40910..41203)
                     /locus_tag="VVR08_000718"
     CDS             complement(40910..41203)
                     /locus_tag="VVR08_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074671.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            41365..41817
                     /locus_tag="VVR08_000719"
     CDS             41365..41817
                     /locus_tag="VVR08_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU6074672.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDI
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41852..43240)
                     /locus_tag="VVR08_000720"
     CDS             complement(41852..43240)
                     /locus_tag="VVR08_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6074673.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43306..44268
                     /locus_tag="VVR08_000721"
     CDS             43306..44268
                     /locus_tag="VVR08_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU6074674.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFRAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT        12636 a        10086 c         8611 g        12990 t
ORIGIN      
        1 aaaaacaagg aaaaagaaag gggtttcacg aatgaagaaa aatcgtggaa ttcaaaaatt
       61 agctatatta gtattactag gtgtttttat gtttagtaac acaattcctt accaacagtt
      121 attcagaaga atagacaatt ggagattcga gtgcaatcac aaaagaagtc caatggtctt
      181 gatgttggga aggctgattg atttcgtatt actttaaaat tcaactattt agagaaaggt
      241 attctgatga gagcttgtaa caataccaga tagatataag aatggagatg tttgataaaa
      301 tgctttcata gctaaccaac tgttgaaaat tatgagttac aaaatctaaa gtatttaaga
      361 ttggtttata aaattaggtc tctgcctgta gaaaggaacg tgcagttaga aaggaggaaa
      421 aaataggata ctataattca gactgagatt tctaattaaa atatgtagtt gcatttcgct
      481 cattttcata atatttcatt tagaggagta ataatatgtt aaaatttaga aaagtagttg
      541 catcatccct tgccgttttg gcatttagtt tggctcttcc tgttttggca gtttctcacc
      601 gtggtggcga gtggacctat ggaggccatc atgatccata taattgggga gcattttcga
      661 attattatca tggttcacag tatcactggg cctatgttgg aagtaatgaa cgtgacaatc
      721 aaaaaacagt ttatgcagga gcacatagtg cggcctatgc gtttgttaat acaaatttgg
      781 gggagcgaat tacatttgat gcgggatggt aaagaataat tgaagaagat tcttttatca
      841 atagtttagt aagcttgtta gtttatagag ggcaggggta tttctgccct ctgttttaga
      901 ataaggaatg cactatgaaa aaattattta tactcatatc caacctgctt gctagtttgt
      961 tctttgtttg ggtatttacc atttggactg atacatatgt ctcccattat taccccaacg
     1021 ttgttgtaca tgattcttcc cctgaaacaa cttttcagca tgttgctaca cgcttggaaa
     1081 aactagcaga agaaacagat agctttattg cgattcaaca ccaagatcct aactcagaag
     1141 gtactacagt tttttcttat acgacctttg gagacggaaa gttgcctgac gggctacagg
     1201 aaaaaaaact agaagatgct caaagtagta gtgttgaaac aaactatttt gtattcgatg
     1261 gacacctaga tattcacttg ctaagggagg agctaagtca acttggcttg actaatatgc
     1321 acctgacaat tccatctaaa ctatctacgt taatggctat ctttagtaac ggatttcagt
     1381 taatcagtct attgattttc atcttaacct ttggagcact gactttaatt agtcaaatta
     1441 gccaattacg gtcgtcgggc attcgcctca tttcaggaga gaaacggtgg tccatttttc
     1501 ttagaccagt tggtgatgat ttgaaaggga tagctgttgg tttcagttta gctggcgtgc
     1561 tcaccattct tatgcaaaaa attctgtcgc ttccaacgca atccctaatg accataggag
     1621 caggcttgct cagttataat ctcatcttgt tgtctatctc cctgtttttc gctcaactct
     1681 tcgcagttgg gataaaaaag atacacctga tgcagattat aaaagggcaa gtgcctgtca
     1741 gaggaatcat tagtttgatt ttaatcggtc aactattagc gattattatt gtaacgctgg
     1801 gaatagggag tagcttaaag tattcccaag cctggcaaca gcatcggatt ggacaagagg
     1861 cttggagtca ggaaaggcaa ctgattaccc tatcaatcag ccgtgaagga acgagtcctg
     1921 gttttgatga acaagctcaa aggaaactca gaacttggta tcaattgatg gatctggctg
     1981 tttcagaaca aaaggctttc ttatctagac accagttaat tgaccgtact ttgcaaaatg
     2041 gcatggcttc ctccaaaaac tttataacct ctacagaatg gcacgattac agcccgaatg
     2101 gcaatgtcct tatcgtcaca ccgcaatact tggagcgtca aaacattcct gtagatacaa
     2161 ctattgagca aaagatgaat caccttgatg taggggagtt tgtcttattg ctgcctgaac
     2221 acctccgttc agaggaagaa cattataaat ctgtttttga agacgactta accagtcgca
     2281 tgtctagtca agatgaacga cagcaaatga ctgctacggt aggttattta gaatcaggtc
     2341 aggatcgttt tgtgtataat acgaccccta tttcttacca gcagtttttg aaagatccaa
     2401 tcatcattgt tataacaccc caatcaactg gtccacagtc cattttgttt tggatagacg
     2461 cagtacagaa ctacgttctc tttaatcaat tgtctgatgc ccatgagctt atccagagac
     2521 aaggcattga aaattgggtc tcagaaatgc aaacaggtta ccacaactac atcacattat
     2581 tggataatat ccagagggaa cgttgggtaa tgctagcagg agctgtgctt gggattgcaa
     2641 cttcaatctt gttgtttaac actatgaata ggctctactt tgaagaattt agacgtgcca
     2701 tttttatcaa acgcattgca ggtctcaggt tcttagaaat ccatcgcact tatctctttg
     2761 ctcaactggg tgtgttttta ctgggatttg ttgcgagtgt atttcttcag gtagagatag
     2821 gagttgcttt cttagtcttg ttactcttta ctggtctatc tcttttacag ttacatgtcc
     2881 aaatgcagaa agaaaacaag atgtccatgc ttgttttgaa gggaggttaa tatgattgaa
     2941 cttaaacagg tgagtaaatc ttttggagaa cgagagttat tttcgaatct ttcaatgaca
     3001 tttgaggctg gaaaagtcta tgccttaatt ggttcaagtg gtagcggaaa aacaaccttg
     3061 atgaacatga ttgggaaatt agaaccttat gatgggacga ttttttaccg aggtaaagac
     3121 ttggccaatt ataaatcgag tgattttttc cgtcacgaat tgggctacct cttccagaac
     3181 tttggcttaa ttgaaaacca aagtattgaa gaaaacctta agctaggtct cattggtcaa
     3241 aagttgagtc ggtcggaaca gcggttgagg cagaagcagg ctttagaaca ggtcggcctg
     3301 gcttatctta acctagataa gcgcatcttt gagttatcgg gcggagaatc gcaacgggtt
     3361 gccttggcaa aagttatctt aaagaatcca ccctttattc tggcagatga gccaacagct
     3421 tcaatagacc cagcaacttc tcagttgatt atggagattt tgctatctct tcgagatgat
     3481 aataggctaa tcattatcgc aacacataat ccggcaattt gggagatggc tgatgaagtg
     3541 ttcacgatgg atcatctgaa ataaaaatcc ttgtttttaa ttgcacgatg agttactgaa
     3601 atattatcat gaatcaagaa ttggagttaa tttagaattg tactttatta atattgaggt
     3661 aactttttct tgataaagga agaaataatg gagaggaagt tagaatgaaa aaattcgaca
     3721 attatattat tgagaagcct tgcgattcta attcagataa actgcaaaaa atcttaataa
     3781 ttgaaagttt ggtagatgat attttgcaat tttctctcag aatcaataat agtgtaggag
     3841 agattttcct cctacaaccg ttttaaaaga aaactatctt tattccatgt tattttgagg
     3901 aagatattgt gaaagtcaaa gatgatgata aagttgagtg gaatttgtta gaatttcaaa
     3961 aatttagagc atttttggct tagtaatctg tgttgaaggc tcaaaaccta tggtaaaaaa
     4021 gtcgctttga aaacgtattg cctccaaaga tttagttaaa taatgattta acacaaaaag
     4081 aaattattga agttctggaa agatgttgtt tcagtattga gaaaaggtgg gaaaaacttg
     4141 cgattttcac agagaaagga aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga
     4201 acagaacaaa agaacctttt gtgccatatt ttctcctttc gctttacaat tggcttgaac
     4261 acctttattg tatcgagtta ggagtttttt tggtataacc ttcgacgcgc acccgcatag
     4321 cgggtgtttt tttgtctcgc acctaacgga gcgagacaaa ctaatagtca cttaatcaaa
     4381 aaacgcacca tatcaaaaac taaaaagttt gatatcatgc gtcatgtctt aaactaattg
     4441 actatacttt ctattcaaat gagcttttaa ccaattgatt gagccaatcc actcttaaaa
     4501 ccaaagagca atttctcgct tagctgactc ttctgaatct gaaccatgta caacattttg
     4561 gataatatca ttttctccag cagcttttgc aaaatcacct cgaatagtgc ctggtaaagc
     4621 ttcttctgga cgagttgcac ccatcatggt ccgccaagtt tcgattactt tgggaccaga
     4681 aatgacaccc acaagaactg gacctgaagt catgaattca cgaatcggtg ggtaaaaact
     4741 ctgaccaacc aagtcctgat agtgctggtc aatcaactct tctgaaacct gtgaacgaaa
     4801 ctccaatttt tcgattgtaa atccacgttg ttcgatgcgc tttaacactt cacccactag
     4861 ccctcttttt acaccatctg gtttgatgat aaagaatgtt tgttccatac ccgtctcctt
     4921 tgtcagcttc tttcttttat tttaccacat ttcgtggaaa aatggagaaa gttttcagaa
     4981 gagagaatga gagaaccctc gggttctctc attctctctt attctactgt ttcttccaca
     5041 gtttcaacgg cagtatccac aactacttct gttgtttctt catttccttc ttcctctact
     5101 ggaggattaa ggtattcttc ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc
     5161 ataccagtac cagctgggat gatcttaccg atgataacat tttctttaag tccaaggaga
     5221 tggtctttct taccacggat agctgcgtca gtaaggacac gagttgtttc ctggaaggaa
     5281 gccgctgaca agaaactgtt tgtttcaagt gaggctttgg taattcccat aaggactggg
     5341 cgacctgtcg ctggaactcc acctgcgata aggacatctt tgttggcatc tgtaaagtca
     5401 ttgatatcca tgagggtacc catgagaaga tctgtatcac ctggatccat gacacggact
     5461 ttacggatca tttgacgaac cattacctcg atgtgtttgt caccgatttc taccccttgg
     5521 ctacggtaaa ctttttgtac ttcaccgaga aggtacgttt caactgacaa gacatcacga
     5581 actgcaagga gacgttttgg ttggatagaa ccttctgtca gagcagcacc acgcgctact
     5641 tggcccccaa cttcgacacg catacgagct gtaaatggaa cgacatattc accttcgcca
     5701 gtttcaccct taacaaagac tttcttggta cgagttgatg catcttcttc gatagcagta
     5761 acttgtcctt taacctctgt aataaccgct tcccctttag gattgcgggc ttcaaagatt
     5821 tcttggacac gaggaagacc ctgagtgata tcggtatttg aggcaacccc acctgtgtgg
     5881 aaggtacgca ttgtaagctg tgtaccaggt tccccgatag attgggcagc gattgtacca
     5941 actgcttcac caacttcaac cgcatcacca gtcgccaagt tgataccgta acagtgacgg
     6001 cagacaccgt gacgagtgtt acatgtaaat acagaacgga tagtcacttc ttccacacca
     6061 gcattgacaa tttcacgcgc cttgtcttct gtaatcaatt catttggacc aataatcact
     6121 gcaccaattt ctggatgttt aacagttttc ttagtgtaac gaccgttgag acgctcttcg
     6181 agagactcga tcatctcttt tccttctgcg atagaacgga tcaagagacc acggtcagtt
     6241 ccacagtcgt cctcacggat gataacgtct tgggcaacgt cgaccaaacg acgagtcaag
     6301 taacctgagt cggctgtctt aagggccgta tcggtcatac ctttacgagc accgtgagtt
     6361 gagaagaaca tttccaatac cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc
     6421 atgatacgtc cattcggagc agccatcaga ccacgcatac cggcaagctg tgagaagttt
     6481 gagatgttac cacgggctcc agagtccatc atcataacga ttgggttctt aggatcttga
     6541 ttagcaatca agcgtttctc aagtttttca cgggcagcac gccattcagc tgtaacagca
     6601 ttgtaacgct cgtcgtctgt gatcatacca cgacggaatt gtttggtgat ttgttcgaca
     6661 cgtttgtgtg attcttcaat gatttcagcc ttgtcatcaa cgactgggat atcggcaata
     6721 cccactgtca atcctgcaag agttgagtgg tggtaaccga ggttcttcat gcggtcaagt
     6781 agggcagaag tttctgtcgt acggaaacgt ttgaagattt cagcgatgat atttccgagg
     6841 tttttcttct tgaatggagg gttgagctca agattgctga tagcttcctt gatatctcca
     6901 ccaagtggca agaagtattt agctggaaca ccttctgtca agttggcatt gtttggttct
     6961 tgcaagtatg gtagcccctc tggcatgata tcgttgaaga gaattttacc aactgttgta
     7021 agcaagacct tatgtctttg ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata
     7081 ccaacacgtg agtggaggtg aacataacca ttgcggtaag ccataaccgc ttcgtcacgg
     7141 tctttgaaga ccattccttc accttcgcga ccagcttctt ccatggtcaa gtagtagtta
     7201 cccaaaacca tgtcctgaga tggagtaact accggtttcc catctttcgg gttcaagatg
     7261 tgctcagcag ctagcatgag gatacgagct tctgcttgtg cttcttctga aagtggtacg
     7321 tggatggcca tttggtcccc gtcaaagtca gcattgtagg cttcacagac aagtgggtgc
     7381 aagcgaagag ccttaccatc aatcaagact ggctcgaagg cttggatacc caaacggtga
     7441 agggtcggtg cgcggttcaa aagcactggg tgttctttaa tcacttcttc aaggatatcc
     7501 cagatacgct catctccgcg ttccaccaag cgtttagctg ctttgacgtt ttgcacgata
     7561 tcacgggcaa cgatttcacg catgacaaat ggtttaaaga gttcaatcgc catttcacgt
     7621 ggcacaccac attggtacat cttaagagtt ggaccaacgg cgataacgga acgtcctgag
     7681 aagtcaacac gtttaccgag caagttttga cggaagcgtc cttgtttacc tttaagcatg
     7741 tggctcaatg atttcaatgg acggctacct ggtcctgtga ttggacgacc acgacgacca
     7801 ttgtcaatca aagcgtcaac tgcttcttga agcatacgct tctcattttg aacgatgata
     7861 cctggtgcat ttaactcaag caaacgagcc aaacggttgt tacggttgat aacacggcgg
     7921 taaaggtcat tcaagtcaga tgaggcaaaa cggccaccat ccaactgcaa cattggacga
     7981 agatctggtg ggataaccgg aaggatgtta agaatcatcc attcaggttt gtttccagac
     8041 ttgtaaaagg catccaaaac atccaaacga cggatggctt tgacacgttt ttgtccagta
     8101 gcagttttca attcttcttt gagttcagca atttcttttt caagatctac ttgcttcaaa
     8161 aggtcttgga tggcttccgc acccatctta gcaacaaatg aaccataacc atattcacgc
     8221 aagcgctctc ggtattcgcg ctctgtcatg atagacttgt gctcaagtgg tgtatcctta
     8281 ggatcaatca ccacataagc cgcaaagtag ataacttcct cgagggcacg agggctcata
     8341 tcaagggtca agcccatacg gcttggaatc cccttgaagt accagatgtg agatacagga
     8401 gctttcaatt cgatatgtcc catacgctca cgacgaactt tcgtacgcgt tacttcaacc
     8461 ccacagcggt cacaaacaat tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat
     8521 tcccagtctt ttgtaggacc aaagatcact tcatcaaaga gtccttcacg ttctggtttc
     8581 aaggtacggt aattgattgt ttcaggtttt ttgacttctc cataagacca tgaacggact
     8641 ttacttggag aagctagggt gatttgcata cttttaaaac gatttacatc aaccactatt
     8701 tcttcccttt ctattctaag tgaactgctt attcttgttc agcagcttct tctgttgctt
     8761 ccgcttttgt tgctttctca gcttcttcag cttcaaaggc tgctttagcc tcttgggctg
     8821 ctttttcgcg ggctttttca aggtcatcta cgtggatgac atcttcgtcc attccttcat
     8881 ccaagtcgcg aagttccact tcttggtcat cttcgtctag gacacgcatg tcaagaccaa
     8941 gagattgcaa ttctttgaca agaactcgga aggattctgg aacacctggt tttggaattg
     9001 gtttgccttt tgtaatagct tcataggctt tcaaacgtcc gttgatatcg tcagacttgt
     9061 aagtcaagat ttcttgaagg acatttgacg caccgtaggc ttcaagagcc caaacctcca
     9121 tctcaccgaa acgttgtcca ccaaactgag ctttacctcc gagtggttgt tgggtaacag
     9181 ttgaataagg tccgactgaa cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga
     9241 tcatgtacat gactccaaca gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt
     9301 aaaggattgt cttggcatcg ctatccatac ctgcttcttt aacagttgac caaagatctt
     9361 cagaacttgc tccatcaaag actggtgtcg caatgtgaat accaagagta cgagctgcca
     9421 taccaaggtg aagctccata acctgaccga tattcatacg tgatggcacc ccaagtgggt
     9481 tcaacatgat gtcgactgga gttccgtctg gaaggtaagg catgtcttct acaggaacga
     9541 tacgagagac aacccctttg tttccgtgac gtccggccat tttatctccg accttaatct
     9601 tacgtttttg agcgatgtaa acacgaacca acatgttaac acctgattgc aactcatctc
     9661 catttacacg tgtaaagatc ttaacatcac gaacgacacc atcggcaccg tgtggtacac
     9721 gaagagaagt atcacgcact tcacgagact tgtctccaaa gatagcgtgc aagagacgtt
     9781 cttcagctga aagatctttc tcacccttag gtgttacttt acctacaaga atatcacctt
     9841 ctttaacctc agcaccaata cggataatcc ccatttcgtc aaggtctttg agggcatctt
     9901 caccaacgtt tggaatttcg cgagtgattt cttcaggccc aagctttgta tcgcgcgttt
     9961 ctgattcgta ttcttcaagg tgaacagatg tgtagacatc gtccttcacc aagcgttcgc
    10021 tcatgataac ggcatcctcg aagttgtaac cttcccaagt catgtaggca acgattgggt
    10081 tttgtccaag cgccatttct ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt
    10141 tttcaacgac atcaccaact tttacgagag tgcgttggtt gtaagcagta cctgagtttg
    10201 aacgacggaa tttttggatg tggtaaacat ccaatgaacc atcttcacga cgaacttcta
    10261 ccttgtcagc atctgcgtaa gtaactttac catcatactg agcaatcaca gccgcaccag
    10321 aatcgtgggc tgcttggtat tccataccag taccaacgta aggtgcctga ggattaatca
    10381 atggcacagc ctgacgttgc atattggctc ccatgagggc acggttggag tcatcgtttt
    10441 ccaagaaagg aatacatgct gtcgcaacgg caactacctg ttttggtgaa acgtccatgt
    10501 agtcaacaat attagctgga tactcttggt tgaccccttg gtgacgtccc atgacaatct
    10561 tctcagcaaa ggttccatct tcattcagac gagagttagc ctgagctaca gtatattcat
    10621 cttcttcatc agctgtcaac caaacaattt cgttcgtgac aacacctgtt tcacggtcaa
    10681 ccttacggta tggtgtttga acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt
    10741 tattgatcaa accgatgtta ggtccttcag gtgtctcgat tggacacata cgaccatagt
    10801 gagtgtagtg cacgtcacgt acttcatatc cggcacggtc acgagtcaaa ccaccaggtc
    10861 ctaaggctga caaacggcgt ttgtgagaca actcagaaag cgggttgtgt tggtccatga
    10921 actgtgacaa ctgtgatgaa ccaaagaatt ctttaaccgc agctgttaca ggacggatat
    10981 tgataatttg ttgtggtgtc aagacttcat tgtcctgaac agacatacgt tcacggacat
    11041 tacgttccat acgagaaagt cccaaacgta cttggttggc aagcaattca ccaaccgcac
    11101 ggatacgacg atttccaagg tggtcgatat catctacacg gccaagtcct tcagccaagt
    11161 tgaggaagta gctcatctca gcaaggatat ctgcaggagt caccgtacga accttgtcat
    11221 ctgggttagc attaccaatg atcgttacga cgcgatctgg atcagttgga gcaacaacct
    11281 tgaatttttg aagaacaaca ggctcagtca caacggctgc atcgtttggg atgtagacaa
    11341 tcttgttcaa gtcgccatcc aaatggcttt caatgctttc aatcacgcta cgagtcataa
    11401 tcgtaccagc ttctaccaag atttctccag tttcagggtc taccaatggc tctgcaatgg
    11461 tttggttgag caaacgtgtt ttaacattga gttttttatt gattttgtaa cgaccaactg
    11521 ctgccaagtc atagcgacgt gggtcaaaga agcgagccac aagcaagcta cgtgagcttt
    11581 cagccgtctt aggctcacct ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg
    11641 tacgagagtc cattggattc ttgtggatat ctttttcaac agtgttgcga accaattcgc
    11701 tgtcaccaaa aatatcaaag atttcatcat cacctgagaa accaagagca cgaaccaagg
    11761 ttgtaaatgg aatcttacga gtacggtcga tacgagtgta ggtgatatct tttgagtcgc
    11821 tttcaagttc caaccaagct ccacggttag ggataacagt tgaaccatag cccaccttac
    11881 catttttgtc tactttgtcg ttaaagtaaa cacctggtga gcggaccaac tgagaaacga
    11941 taatacgttc accaccattg atgatgaaag tacccatttc tgtcatgatt gggaaatcac
    12001 caaagaaaac ttcctgggtc ttgatttcgc ctgtttcttt attgatcaag cggaaggtta
    12061 caaaaattgg tgctgagtag ctagcatcgt ggatacgagc ttcttctagc gtgtattttg
    12121 gttccttgat ttcatatcca acaaattcca actccattgt gtctgtgaag tttgaaattg
    12181 gcaatacatc ttcaaacact tccttaagac cgtggtctag gaaagctttg aatgagtcag
    12241 tttgaatttc aatcaaattt ggtaagtcaa gaacttcttt gattcttgaa aaactacgac
    12301 gggtacgatg tttcccgtat tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat
    12361 aagttccaag ccttgtcaat caggcttttc taatcgccat atggttgtaa accccttatc
    12421 accgtgtcct cttgacgaat tttcagaatc tttaagcctc tgttacaaat gctcaaaatc
    12481 ttgaaaaaaa gcacaaaaag agcagctaaa tctgactttt tcagaagatt taactgctgt
    12541 gagccttgtc tggacaatat ttcagacaaa acctacgaca aatgattacc catattatac
    12601 cctatttagc tagatttttc aaggggtttc agtaggtttt tggtaaattt tttcccatag
    12661 aaaacttggc atcacattcg aatcacgcta tggtacaaaa aactgaaaaa actattgact
    12721 gaaaatcatt ttcaaggtat aataataaac gttaaggcgg tatagccaag tggtaaggca
    12781 cggctctgca aaagcttgat cgtcggttca aatccgtcta ccgccttcta taacttgatt
    12841 tatcaggttt caaatgaaca gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa
    12901 taaatacgta taactttaaa aacttttgga gcgagtttgt ggcagagttc tttccatggc
    12961 ataattccct tttgaaatca attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct
    13021 agtttattct gtttcttctt ctatttcgac ttctgtgatt tggactttta ccttggtaac
    13081 acgtccattc ttcactttat cattggttaa gataaactgt ttgttttggc tgaccaattc
    13141 atagctgagt ttctcagtcg ttggaatagt tcccactcct gtcaaataat aaccagcgat
    13201 ggtatcaacg tcatcacttt ccagttcaac atcaaagtaa ttattgaaat cattgagggt
    13261 catagttcct tgaacaatgt aggtatcctc gccaatctga tgaacatcta ttgctgcttt
    13321 gtccgtttca tcatcaattt caccaacaat ttcctctaag aggtcttcca aagtcactaa
    13381 accagccata ccaccgtatt catccagcaa gattgccatt tgtctttggg tatttcgcag
    13441 ttcttttagc aagtcatcca caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat
    13501 tctcttccaa acaatattgt caaaaccgtc cacaaagcct gccttaagga gactcttggt
    13561 gtgaatgatt ccaattacat tgtccttatc cccatcataa accgggatac gagaataatt
    13621 ttgttttaaa atactttgga taatggcttg actatcatcc tgaatatcca ccataaaggc
    13681 atccgttcga ggaaccataa cctctcgtgc catcagttca tcgagcgaaa agacaccttg
    13741 tagcatctca atctcatcag catccaatgt ttcttcacta tttgtcagca tataggcaat
    13801 ttcatcacgg gtcatttttt catccgcatc atcgaatgac ataggagtca aatggctcaa
    13861 gaaattggtc gaagcagcta aaagccaaac aaaaggactg actagttttc cgatcccaat
    13921 gataaccggc gctgtacgaa ttgccaaggc atcctttaga ttaagagcga ttctcttagg
    13981 atataattcc ccaaaaacga tggaaatata ggtcaaaaat gccaaggata gaaaagttgc
    14041 cacggcttgt gctgtttcgc cattcccaag ccaagaggca atcacacgtc ctagagtatc
    14101 agttaaactc gcccctgata agattgtaat cagggtgatt cctacctgaa tggttgataa
    14161 aaagtggtta ggattttcta gtaccttcag caggcggatg tagcgtctgt ctccttcttc
    14221 cgccttttgt tcaactcggg cacgattaag agaaaccatg gccatttctg tggctgagaa
    14281 aaaggcattt aatacggtca agataaacaa taaaacaaat tgtagcaaca aattctgact
    14341 acttgggtct tccatagttc ttctcctaaa atagtatctt atcctttatt atatcacaaa
    14401 atttaatcca atacatatta tttttttctt agcgtaactt ccatactgga agttagtcta
    14461 agacggattt ccactgattt cacgcgtttt tctcatacta aaagctaggt tgtgggaaac
    14521 tggaagttag ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac
    14581 tagtaaaaag aactcctaca tccataagtg acataggagt ttaggcttat cttttactga
    14641 gttacagtta cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact
    14701 agaacattga attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga
    14761 actaaatcct cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg
    14821 tccaaggctt tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt
    14881 gcctgatttg cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca
    14941 aaaccatcca aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg
    15001 gtataagagc cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa
    15061 ccattcccag tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta
    15121 gctacggttg gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta
    15181 cttgaaacct tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca
    15241 ttccactcca gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc
    15301 aatgcttgac taggagcttc aggcgcttgt tttttctgac taagattggt tttgggacta
    15361 ttaggtgccg actgcatctg cttgatataa tagctccctg tagacaaaag caataacact
    15421 agcagtccga ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa
    15481 aggctggttc tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg
    15541 gagacaggac agcccatgga tcttgaccct tgcccaagat tccataacct accattagac
    15601 cgattcctag agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga
    15661 ctacgtagct tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca
    15721 cctagctgag ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta
    15781 ccgaccacag tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga
    15841 aggtcagttg aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta
    15901 tcacggataa tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga
    15961 ttttcgaaaa ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta
    16021 aattgagcct gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct
    16081 tttagatttt ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca
    16141 cccatttcaa gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc
    16201 aagacatcac caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtcc
    16261 tggactacat tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct
    16321 gtaccagcac ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc
    16381 tcaggctcac gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc
    16441 atcaagttct gcgttgcacc aacacttgga aagtccatat agatatgagc accatgcaag
    16501 cgttctgcct tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc
    16561 agacctttca aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat
    16621 accttggcat gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc
    16681 ttgctgacat acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca
    16741 agatgagctt cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata
    16801 ataaagacat ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga
    16861 atagtcgctg ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct
    16921 accagacgat tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt
    16981 gattttataa taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag
    17041 aactcaggat gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg
    17101 tattatcatc tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa
    17161 aactcacata aataaagaac atatgactac ttagagtgaa taataattga accatttgac
    17221 tattatacca tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat
    17281 tgtttttcaa gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg
    17341 tcttgattgt tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg
    17401 ccttttgttc ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc
    17461 tagccgaagc tacaaccttc ttatcaatac ctccaatgtc tcccacatta ccatcgcggt
    17521 caatggtacc tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag
    17581 tatagatagc tagactaaac atgagaccag cacttggacc gccaatacca gctgttgaaa
    17641 agctaattgg gacattgctg attacctctg tacggtcaat caagccgatt ccaattccat
    17701 ttttgccatt ttccaaggtg atgatttttc cttctgcaga cttggtttgc ccatcctctt
    17761 cataggtgac cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt
    17821 tggaactatc aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc
    17881 ctttaaaggt tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga
    17941 tatccttacc agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt
    18001 agaattgatt gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac
    18061 tacgaatatc tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt
    18121 gaacaccaac cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttactt
    18181 taaggacttg gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca
    18241 ctacaaatgc caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct
    18301 tttttttcat ttcttatttc ctccaaaata ctctcgggaa catagcaggc aatatcctga
    18361 ccaaacttca aaagctctct aacgcctgat gaactgatat agagatgttc aggtcgacta
    18421 tgtaaataaa tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactggct
    18481 tcatattgca aatccgacgc atttctcaag cctcgcacta ggcaagtagc ccccagtctt
    18541 tttgcgacat cgaccaccaa tttatcatga gaagacacga ctttaacatt tcccaaatgt
    18601 ttcacagcct tttctaaccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg
    18661 ggattaaaaa aaatacccac ataaagctta tcaaagagtc tgctcgcccg ttcaatcata
    18721 tccagatgcc catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac
    18781 atagactgtt accttactaa ttccataaat cttttccttc cagataccca gacaggcaat
    18841 ttcttctgga agttcaacgg ccttatccgt ctcgcacaca accataacat cttcagaaaa
    18901 aagctctctc tcagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg
    18961 gtctaagaaa atgaggtcaa attccccaga tacctgttcc aatgcccttt ctgcatccat
    19021 cttgaggagt tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt
    19081 ctgagcctta cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc
    19141 gatagataaa ccaccactac ctgcataaag gtccaagact cgtccccctt caaagtaggg
    19201 accaatcatg ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg ttgtcttgcc
    19261 ttctagtgtc ttaaggggac gtcccccata gattcctgat atgattttca tactgtttat
    19321 tataccaaat tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca
    19381 aaatattttc gtaagtatcg cggacttctt gaggccaaac acttgtttgc acttctccga
    19441 tgtgtctctt gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg
    19501 tcaatgggaa taggccattc aacaaagact tgtgccattc caattccaag cggtcttcat
    19561 cacctgtaat ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag
    19621 acaactcaaa ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct
    19681 tgtagccatt ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg
    19741 gtttaccatc tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac
    19801 aaatcgcatt ttcacgttct ttcggtgtca agtctgggta gcgttctacc aattcttctg
    19861 tatggataaa ggtgatttgt tttggcaaga tagactcgat gtcatagcgg gcttcaacag
    19921 ctagctcagt caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga
    19981 tgttacgctt accatttgga ataaccttct cccagtccca ctggtcaaca taaacagagt
    20041 gggttgcatc caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct
    20101 ctccttcacc aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca
    20161 ccacttcata agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac
    20221 cagacaggtt gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga
    20281 caacttctag cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt
    20341 cttgttgatg gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt
    20401 atacacctat ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa
    20461 cactgatttc atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa
    20521 gattgataaa atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac
    20581 gaccttgtga ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg
    20641 aaaaaaccaa aaccatggct acgctaatca tataatcaaa gaagccacta gccaagaaaa
    20701 tattgactac catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc
    20761 cactcaagtc tttcttggta aaaataccaa ctgccgccat gacaaagaag agaagggcgc
    20821 tcgatacaaa ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg
    20881 taaagccgtt taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg
    20941 aagccatgct actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc
    21001 agagacgccc ctgcatcaac aagtaaacca actgagactg aaagaccgtc aacataaggc
    21061 ctgataccaa agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa
    21121 attgattgag acctgcacgg tcatgtataa tagtgtgatt catccttttc tccttttctg
    21181 tgaacatctt tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa
    21241 ataccggctg caactgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc
    21301 aactggtctg cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact
    21361 agtacaaaat tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt
    21421 gttgctagca ctgggatagc taccttttta gtttcgtcaa gaagcgcttg actagtcatc
    21481 cggtaaatgg gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag
    21541 atgtctgccg acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga
    21601 atgatagttc ctacattacc aggatcttgc acatcttcca aaaacaagaa cttgccctga
    21661 ctcaaatcag cttgtcctac ttcttctttt tgaaccacgg caacaattcc ctgtggagtc
    21721 tgagaatccg ccaaatctag caaaatatcc tctgaaatcc agacagtttg cggaaaagca
    21781 gctaactgat ttcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg
    21841 acagcttctt caaacaagtg ccagccttca atcaaatagg cagacttgcg gtattttttt
    21901 tggtgtaatt tcttagcatt ttttaccaca gaattggctt ttgaggttat aatagtcata
    21961 gaaatattat aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag
    22021 gtagggtgca gggagtcggc tttcgttggg gtgtttatag cctggccctt gaaatcggtg
    22081 gcatcacagg tcgggtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag
    22141 actcatctgc tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt
    22201 caaaagtaag ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa
    22261 tcgcaaatta ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg
    22321 tataattttt aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cattctcggc
    22381 tatgggagtg gctatgttgc ttgtcttgac tggctgtgtc aatgtcgata aaaccacagg
    22441 tcagccaaca ggatttattt ggaatacgat cggagcgcct atggctgaag ccatcaagta
    22501 cttcgctact gataaaggtc taggctttgg tgtcgctatc attatcgtaa ccattatcgt
    22561 acgcttgatt atcttaccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga
    22621 aaagatgaac gctctcaagc atgtccttga gccacaccaa acacgtctca aagaagcaac
    22681 tactcaagaa gaaaaactcg aagcccaaca agccctcttt gccgctcaaa aagagcacgg
    22741 tatcagcatg tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc
    22801 tgctatctac tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat
    22861 tcctctaggt tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca
    22921 atcgctcctt tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat
    22981 gatttacatg agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac
    23041 actttactgg gttgtcggtg gtttcatgat gattctccaa cagtttatcg tcaactatat
    23101 cgttcgtcca aaacttcgca aaaaagtccg tgaagaacta gccaagaacc caccaaaagc
    23161 aagtgctttc tctaaaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat
    23221 cacaagcaag aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga
    23281 aaaaggctta gctgatttgc taagtctttt tgcaaatcaa aagcccgatg tttccatcag
    23341 gcttcttttc tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag
    23401 ttttttagcg ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg
    23461 aattccaagt tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt
    23521 atcaacattt ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc
    23581 tgtcaatcct ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata
    23641 ctgggcacaa gccaagatat ttttattagt ttggctagtg acaatcttgt gctgttcttc
    23701 gttgatttcc ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt
    23761 ctcaaggtaa cgtggtttat tacggaaagg aagagcacag gtatccaagg tacagtggat
    23821 tccttgttcc ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc
    23881 tcctccactg actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc
    23941 tgtcaagaca tcatctactg tccgttcacg tgacttattg gactccatag cccaagtgtc
    24001 tgggttgtgg caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat
    24061 accaggccca tctactgacc caaagctttc tgtcgaatgc accattcctg tcacttgtcc
    24121 ataatcaatt gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat
    24181 tatatcacga cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt
    24241 ttcaatttca ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt
    24301 gcaaaatagt cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta
    24361 tagaggattt ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg
    24421 gcacctgtat catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattc
    24481 actgcaaatt tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt
    24541 ccatctggat gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg
    24601 aggttgactg ctgaggcatc cacacctaga taggtacggt aggtttcctt cttatgagtc
    24661 actcttgtga ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc
    24721 ttgacctgac caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca
    24781 ccaatcaagg cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca
    24841 gaaagattga taaagtctag cgaaatgccc aacttttcct tgatttcaac agccagttca
    24901 aagagctgac gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag
    24961 gagtgaatcc caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc
    25021 tggtccttgg tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt
    25081 tcaaaaacgc ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc
    25141 tccagatgtt caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca
    25201 taggcgtatt ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag
    25261 tccagtttat ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct
    25321 tcttggagaa ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta
    25381 aagcccttgt tccacgaaaa agcttggttg acggctcttg ccttctcacg aatccccttc
    25441 tcatcataca agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta
    25501 ttgataaatg gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca
    25561 atcgttccaa cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca
    25621 acatcgatgg cttggttctt gacatcaata ttggttacct tcaagagtga cttgtagtca
    25681 aactgctttt cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct
    25741 gagtcgaact cgcgcaagag actaatcata ccattgaccg ttccgccacc tttcaagaag
    25801 tcatccacaa tcaagacacg gctgcctgcc ttaagactac gttttgaaag gaacattttc
    25861 tcgatacggt caccacttga acctgaaaca tagttgacgc taacagttga accttcggta
    25921 attttcaggt cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt
    25981 gcaagtggca cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag
    26041 cttttggcaa taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac
    26101 agatagatat aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct
    26161 tcaaccattt ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca
    26221 gccccagtca ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg
    26281 acgatatctt ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga
    26341 ctagttagtt tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt
    26401 cttcttaatt tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact
    26461 agaaagctgg tcgctggtgg ttcaaaacac tgttttgaga ttgtcaatag aactgacaaa
    26521 ccctgtaata tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga
    26581 ttttcgaaga gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg
    26641 aacattctta tcctaaaaaa tgctcatttt tcttaaatta tcaatctaaa tctggtttat
    26701 agaaggaacg attatccata gcgaagattt tattggtcat ctctccttta tccaccaaag
    26761 ccagagctgt tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct
    26821 ctgcctccat aatacgtgga cggactggac ttccatattc aagcaagccg tggtgactga
    26881 ggatgacatg acgaagcaaa acgacttctt ccttggtatc atcgatgccg agttccataa
    26941 ctgtcttggt aatttcgcta tcaatgagag cgatatgtcc aagaagatta cctcgcactg
    27001 tgtactctgt ctggtctggc cccgtcaact cgataacctt agctaagtca tgcagcataa
    27061 tccccgcata gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca
    27121 aacgcaccat ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct
    27181 tggcagctgg ataggagtag aattccttat catacttggt gtagagattt cggacaatcc
    27241 gttgccagac aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct
    27301 tgacatcaac tggtgacttg accttgaaat cagctgggtc attgggttca ccagcttgag
    27361 gcaggcggag agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt
    27421 tcatgtggac aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga
    27481 gcttcccatc aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag
    27541 ctcgagtttg cctcaggtca gctgatttga ttaggtaaaa gccttcaaat aactcatctt
    27601 ttttcatgtg actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc
    27661 gcaggctcac cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga
    27721 cggtttaata attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc
    27781 agaataccac caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg
    27841 tcggcactct tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct
    27901 gatagggtac ttggtcctgc aacgataatc tgttcttccc gtctcaaatc atcaaagaag
    27961 accggattgc gcacaatctc tgaataaaga ccttctgtcg gaacaaacaa gattccaaaa
    28021 ttggttgtcc gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg
    28081 cttgctagga gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct
    28141 tcttccaagc ggtaataatc tgccagtgga aacttagagt caattggcag atagacgtat
    28201 tcttggtcgc cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca
    28261 accgttgcgt attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc
    28321 agttgcaatt ctcccagaat acctcgcgtc ttggttccag agagaacctt gttaagagct
    28381 ccgacatcac gggcaactgt ctgcatttct ccaaggccac gattgacaga ctccagttgt
    28441 ttagaaactg tttcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc
    28501 tcgaccgtct ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga
    28561 cgttggtctg tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg
    28621 gtcaggcctt ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac agccacttcc
    28681 aaatcttttt ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg
    28741 tctgacaaat gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc
    28801 tgcctttgcc aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa
    28861 ctttccatcc tacctcctgt ccttgctatg cagtacgacc acataaccat ctgggcaagt
    28921 taccgacact tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt
    28981 ctcctctgtc aactcatact tagctccaag aatagtcagc tggctatccc gaactggcat
    29041 aaaggctaga tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctgaacaata
    29101 ggcaatcaaa ttttgcccat cctcaatttc tatttgacgc atatagggtg ccaacttagg
    29161 attgctaggt agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa
    29221 aatagtgacc tgagcctgag gattttgttc aaagatggtt aagagagcca attccagatc
    29281 tgtatcatcc ttttctggtc gggcttggac aaaatactgg gcacgttttt gaatcacctg
    29341 tcgctcttct tccgtcacag aatcaaaatc tccaactgct agagcaagag gtaagtcttc
    29401 ttccaagacc cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata
    29461 atgaccgcgg tttccgcctg caaaaactgc aaccctagtc cagttgtttt ctgagagttt
    29521 gtactcgctc attgacttct cccttaaaga cataggaacc tgctacaaaa acagtcgcac
    29581 cagcttcttt ggcttgagca atagtttggt catcaatccc accatccact tcgatttcaa
    29641 agttcaaacc tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg
    29701 gcagaaaggc ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta
    29761 gatgaaggac gtgcttgatg gcttcaactg gtgtgccagg attgataacg actgaaggct
    29821 taactccgag tgaacgaatt ttttggaggg cgccatgaat atgaggtgtt gcttctacat
    29881 ggatactgat gatgtctgca cctgcacgcg caaaatcttc cagatgatgc tcagggtttg
    29941 acaccatcaa gtggcaatcg aaaaccatct tactatgagg acgaaggctc tcgaccacac
    30001 ctgcaccaaa actgatttgc ggtacaaaat gactgtccat gatatcgata tgggcatatt
    30061 ctgccccagt tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca
    30121 gaattgacgg agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg
    30181 ctgacttttt tataggtttc tctacgattt tcaatttcac taaggaattg caggtaattg
    30241 tcaaaacgga aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc
    30301 tcatgggtat gggtacaagt acggaactta caatctcggc taacagtagc aatctctggg
    30361 aaagcctgat tgaggtcttc agcccttgat acttcatagt ccaaggatga aaatcctggt
    30421 gtatctgcga ttttaccccc gttgagattg taaaaactaa cagctcgagt ggtatggcga
    30481 ccgcgaccta gactgtctga aatttctccc gtttcaagat tgaggtctgg tgcgatttta
    30541 ttgagaagag ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt
    30601 aacaaagaca ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc
    30661 tgctggtaaa aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca
    30721 atgggatgga tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta
    30781 aaatcaggtt ccttgacgga catgattact acagcttgat cgatattgac aataggcgga
    30841 cgaaccagac tgtttttccg ttcgtgaatt ttgaggatat agccttctga attttcctcg
    30901 gcagagaaat ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca
    30961 cgcgcgcgtg tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct
    31021 ttaatgattt gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagaccggc
    31081 aaattctgcc aagctgagag cttccccacg cacacttggt gacaagcctg tctggtccaa
    31141 agccttggtc agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt
    31201 ccacaaggtc ttgcggcgat gggtaaaact agccttggaa accttaaaga aaaagttctc
    31261 atcttctact gctacggctg gctctggacg acgcaccatt ttcaagatgg ctgaatccac
    31321 atttggcgct ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta
    31381 atactgcacg gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg
    31441 gtccgctact tctttctgca tcatgaccac aaactcacaa aaaggaatgc cactctcaat
    31501 caagtgcatg agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg
    31561 caggtcagga tttttaaaat tctggatatg ttgcgccaaa tcaaccttga gaatatcttc
    31621 gttaactaca gtcacattat caaaatcacg cagggtatct gccaaaattg gcaccaaacg
    31681 gtggtcaatc tcaaaagcca tgacttgggc tgcacgctca gccagaaact ccgtcaaggc
    31741 accaatacct ggcccgattt cgatgacatt gacctggtca tcaatttcag ccgtatccac
    31801 aattttttga aggatattgg tatccgtcag aaaattttgc ccgaaggact ttttaaaggt
    31861 aaaaccgtga cgctccagca ctgccttggt cacgctataa tctgcaattc tcatctattc
    31921 tcttttctat tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa
    31981 atcataccaa aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaaagt
    32041 ggccttaaca gttctctcga aacatgcgtt caaaaaaatc agcttcttga taacttcgat
    32101 tttcaggtag ggtcaaatcc acatcctcct ccacatcatc cactgtcagt tcaaccgtct
    32161 gaggtaaatt tttcaaacga taatgctttt gcctttgccc ttcaatacta gcaaaatcaa
    32221 gcaaatagcc atgcactcgg atttgaacca aaaggagatg attggtcata ttttccatga
    32281 tgaggatatc ttctaaacca cctctggcac taggataatc agataccctg cgaatacgga
    32341 ttttttcaca catgagcaag tttcctcata tcaatgattt catcagcctt attccagact
    32401 aggggattat gggtcgcaat gatgataatt cgattttcat ctttcaaatc caccaagaga
    32461 ttcataacct cctctgaatt ttcaggatca agagctgctg ttggttcatc tgccaaaatc
    32521 aagggtggat ttttcaaaat agtcttagca agggcaactc gttgggcctc tcccccagat
    32581 aaagtataaa ttttttgttc taaatccaaa taccctagat taactttttc taaagccccc
    32641 acttgccttt ccaaacgttc tacttttgag attttctgac caacaaaacc caaatccaaa
    32701 ttttctttga ttgattggtt ttctaagagg ccaaaatttt gaaagagata gcccatctga
    32761 tctcgaaaat actcacgagt gggaatggtt tttaaatctt tcccctgata gagaaccctt
    32821 cctccatcta tcttttctag ctttcccaag atattcagca gcgtcgtctt tccgcttcca
    32881 ctctttccga ttaaggcata aaccttgccc ttctccagct tgagattcaa accagagaaa
    32941 atcgcgcggt cattaaattt cttttccaat ccttgaatat caatcatctt attttccttt
    33001 caatactgcc atgctaccag cttcttcttt tttgtcctgc cttactaaaa tcaagagggc
    33061 gttaagcgta aacaaagcta caactagagc gctaatcaaa ccatctcttg tcaaaatact
    33121 agataggact aggccaagca agagaactcc tccttgcgcc agtaaatact tgccatgaag
    33181 ctcatagatt gtcataccag caagacgttt aatcataagc tcccgtctga actgctcaaa
    33241 atagagaaga ttcatggaat caaataacaa gatagccgta gacagggtca aaatcgtccc
    33301 aataaggaga gagtaaaact ccacccgttt gtcatttagt accttggcaa aaaatagctg
    33361 gctttttacc aagtaagaaa ccttgtgata cagaccttgc tcttttagag ctgtgatgct
    33421 gtctccatat cgatctagtt tcaaggcact attagccgta gttccccaca acatccctgc
    33481 aacaggtctt gttccagtcg cttgcggcgt tagaactaca ataatcggat cttttaggta
    33541 ctggcgtgtt gtcttgtacc catcattata gaggaaacgt tcctgtcctg tttctgtaaa
    33601 agctagcctt acctgtggga agtagtgttt ctgactcgtc acttctacac tttcagatga
    33661 aaagttttgc aggtaatctg taaacaatcc ttggtagtag gcagactgct ctcgcaagct
    33721 ctcaggcaag atcagcccaa actctccctc agacaagttt tgcatcttgt caataaactc
    33781 tgaagaaacg gtaatctttt cttctatcag atagcgcggc gagacataga taacattccc
    33841 tgacggtatg tagtcactga gacgattgcc atctaggtcc acttctgctc catctgagaa
    33901 attgtcaaca ttgctcataa tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa
    33961 tgtctgccac tcacgattat ccttacgcgt tccttcttca tcggcaaatg cactagacca
    34021 accaaaggat agacggtaac ggtctgagga ctggctccat ttattgctag ctctctccat
    34081 ttcctgcatt tcacggtagt ggggtaggag agctgtcgca ctcgatccga ccaccaatac
    34141 agctaagagt tgccccacca tcatcaatgt catcatccgt ttgagaggga gtttcccttt
    34201 caatagatcc accagactat tttcctgtaa accaagtaga tggacgacac ttagtaaggt
    34261 agaaatccct gccagggtca atccataaag tagaagagca atgatgacca gttgtaccgt
    34321 tgccataaac aaggcacctt gataccagag aatccccaat cccaaaagac tggataccag
    34381 cactgagcag ataagctgtc tcacatcttc taacactggt ctgagagcaa ctccaaacaa
    34441 gctctcacca gctattaagc gaatccctgc ctgacgaagg gatttgatcc gataaatcag
    34501 ggtcagactc ataaaggtca gcagaaaaat agctaaactc agtagcacca taggggtggc
    34561 cgccaatagt aagactatcg aaaatggatc ttctccattc gaaacaaagc cttgatagcc
    34621 aagttctttc aaggtggtct gtaagctcac tccatccaaa cttcctgaca caatcaagta
    34681 agaccctaat aaatcactcg tttctgcact ctccttggag gaaatggtca gaccttctgg
    34741 aagctttccc tcaccataag tggcataggt aaagcgtgtt tctccagctt catttggctc
    34801 aacgattcga cgggcgatga gactattatg ctctaccgcc aagtgactca aagcctctgt
    34861 cacctcttcg cgactagcta ctggttgatt tatcatcatt cctgtcacat caacagaagg
    34921 atagttacca aataaaatct cttctcgatg gtcaacggaa gttatcacca tataaagcga
    34981 taccaatacc attgaaatca aaataaataa acgtttcatc atttcctcca aaaagttact
    35041 tggtcactta gtgagaaggt gaccaagtaa agctaaacaa tagggctata ccattctaaa
    35101 cattatagta gaatgcaact ttctctcccc aagaagtacg aatccatgca cgagaagtcc
    35161 ctccagcacc agcatatccc ttgtcagatg aaccagtttt tctgctaaca actgttgaac
    35221 tatggtattt tgaagggtga tagtagtttg agtaagcacc accgttacct gaaccataag
    35281 tccaaacacc accttctggg tattgaacgg ctgcagaggc aactgctaca cttccaccta
    35341 atgttgctgc aatgctcgct acaagagcta attttttaac tgtttgtttc atattgatac
    35401 tcctctattt ttgattacaa gattgttgag ttacttgctc ctctttccat tatcaacgtt
    35461 gatactatta tattaccaaa tgatattcta aaattatttg tttttctcta aattgtcaaa
    35521 atagcaccct gaaatgaact tttatagtca ttatactcca tctttatcac actatcaagg
    35581 acatcaatgt ccttaaaatc taactatttc atattatttt tagcttatat ctaaaaaaac
    35641 agttctaaag acgaacttta gaactgtttt gatacgagga caaggacatt tttgtcactg
    35701 attcactatg tttataaata tttttttaaa tcttcttgcc attgtttttc taacatagta
    35761 actaaataag aattttctat tatatcagca aatagcttcg atttctgata gaactgttcg
    35821 gcagaaacat aatcattgtt tattattaga gataatttcc actccaacat taatataatt
    35881 ggtttcttct gaaaatcttg tgttttttcc attatatgat taaggctaaa gatataagct
    35941 cctagtgaat cataagacga caagttatcc aaacaggcta gacccgaaaa caaagtgtta
    36001 cttaaagcaa acagatattc tgatgcaatt aattctacat gatttgtcaa acgaactaaa
    36061 aacgaatgaa ttctgttaat ttcttcaatc tgattttgac cttgttttat ctttgtaagc
    36121 actatagcaa aatataagtt gataacttct aattcattta tcaaaaacaa ttccttatca
    36181 taaattgttt taaaataatc gtccagtacg gtttccccgt attctggtcg tccacttcga
    36241 ataacatcta tcgttgctct agtagcttca aaccatactt tttcctcatt aggaagttgc
    36301 tcataaaata aatcctctat ctcttccaaa cacgcttcct tcttatcgta ctcctcttct
    36361 ttaccataga ttggttcacg taaaatctgg tatttcaatt ctaaataagc agaaggaaga
    36421 gctgaaaaat ccggcataag gctataaact ggaactccta gccggcgagc aatataggct
    36481 aacttgggca aactcggttg cgaagctcca ctttcaattc gcgacagttg acgaactgtc
    36541 agttcttgct catctccaca aaaatctgga cgactaattc ctttttctat ccgaatctct
    36601 ttaatttttt gaccaattaa catcagacgc ctcctattct acctgcttcg aaaaatactg
    36661 tgaaacttaa aaaattgtaa cggctacatc tttcctactc ataagatttc atagcttctt
    36721 ccacttctgc caaagtaacc ccaaacaact ctaggcgttt gaggagttgc ttgccgttgg
    36781 aatagccgat tcggagagtc tctccgaggt attctctacg cttacggctg tctgcccctg
    36841 ctagaaaacc aaggcgaatc aaatcgctac gactaatgtc aaactggctc tcatgttcaa
    36901 attgttctgt cacctgagct agagccgttt tcaggtcttc atagctggca tgctcaattc
    36961 ccagagaacg ccccttggtc ttggacttgg gaacagcttc atctcgcttg agaaaggcat
    37021 gctgaactgt tggaatgacc gtcatgatca tgcgccgaat ccgttctcca ttaaaatctg
    37081 ggtctgtaaa gacaatgact ccatgacgtt ggtgcaggcg ctgaatccgc tctatatcct
    37141 gatcattgat ggcagaacct cgagtctcat aggtctccac atcgaaataa cgcttgagat
    37201 tgaccgtatc atcacgccct tcaaccacga taacttgaga aattttctct ttcattactt
    37261 gctgtccagt ccaaaaattc gttctgcatt tgcagtcgtt gctaccgcca gctcttctgt
    37321 cgtcatacca cgcaagtcag cgataaagtc gaccacatag cgagtatagg ctgttttatt
    37381 ttcacgacca cgcttgggta caggtgctaa gtaaggcgca tctgtttcca ccaaaatctt
    37441 gtccaaaagt aactctttag ctgcttcttg gaggtcagtt gccttcttaa aagtcaccac
    37501 tcctgagaag gaaatggtca taccaagatc cacaaacttc tctgcccact caagcgtccc
    37561 tgaaaatgaa tgcatgatac caccacgagg accaacgccc tcactcttga taatctcata
    37621 ggtatcttcc agcgcatcac gggtatggac aacaaaaggc aaatccaagt ccttagatag
    37681 ctgaatctga cggcgaaaaa cctgctcctg cacctctttg ggcgctgtca tccaatggta
    37741 atctaagcca atttcaccta aagccacaac cttgggatgt tttaacttat ccaacaagta
    37801 agcctcaact tcctctgtat aagtaccagc ttctgtagga tgccaaccaa tagtcgcata
    37861 gagctgatca tactcatcta ccaactccaa ggcacgctca atcgtcggtt tatcaaaacc
    37921 aacaatattc atctgtgtca cacccatctc agcagccaag gcaatttctt ctgcctcacg
    37981 acctgcaaat tcttctacat tcaagtgtgt atgtgtatca aaaatcatct cttctaacct
    38041 cgttttctat cttctattat accaaaaaag aggaggggca cctaattttt cggtttcccc
    38101 tcctctcttc aatagagagc tattctgcta tcttttctat ccgatattgc ccatctccta
    38161 ttccacagtt agagacagaa gagattggct acattgatag aatattccta ttcagctaaa
    38221 gtatgtgatt atcttgggtt ctcacttttc tcacccatca ctaggattga tgacttctca
    38281 aaatccccct tataatctaa ctttaagtag agaatagaat tttctagctg ttctattttc
    38341 tacgtctagt ctttcttcct agcaaagcaa aaccacttgt tgccaccact agaccaagac
    38401 tagcaagtgc tgcacttgat gctgaacctg tgttaggtaa ttgtttgcca gcaggtgact
    38461 ggtaggtaac atcttgcatt gttcctgcag ttgcttgcgg tgcacttgtt gtcttaggag
    38521 cagcattagg agccactggt ctcttaggaa ctgtaaccat ggcaatggct tgcactccaa
    38581 tcgtttctgc ttccttcaca tcttccatag ttttcgcatt ttcaatctct ttgagagctg
    38641 cttgtttttc tgcttccact cttgctaaaa gttctgcttt ttctttatca gaaagcggtg
    38701 cgcctttgat ttcatcctgc ttgtccttgg ctgctttttc aatggcattt ttagctgatt
    38761 ctttttcagt agctaattgc ttagaagctt gtgattgagc tgagttttgt gaacctgtgt
    38821 gagctgatcc acccgcctgg ctaccaccgc cttcattcgc attagcatct gagcttccag
    38881 tattgcctcc cttatctcca cctggtgtat tttctagctt atactctggt gtagcttctt
    38941 gagttacaga ttcacctttc gcagattgtt gaactgtatc ttttcctaga atcgtcacta
    39001 ctgaaccatc tgggaatgtg attgttgctg taccatctcc agctacttca actttatagt
    39061 aaaataaaat aataacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
    39121 ttagaaacag aggtgtacta ttctagtttc aatctactat aacatcgctt ccgaatccat
    39181 ttgcatctac tgaacttttt tacaaaaata aaaatcagta gactcgagtt cctactgatt
    39241 tttgatagaa ttcgtttgga ttatgcagcc aaaactttgc gtcctttacg acgacgagct
    39301 gccaatacgc gacgaccatt tttagttgac atacggttac ggaatccgtg tttgcgcgca
    39361 cgacgaagtt tacttggttg ataagtacgt ttcacgatga atacctcctc atagattttg
    39421 tattcgttta gccggctata aagtgatcag ttactaaaca tactttacta ttctatctga
    39481 ttctttcact tttgtcaata gccctaggca aatgtttcca gctttttcga atgcaagccc
    39541 tatctacgat actgtttcaa gaaacgagtc atcttttctt ggatttgggc taactcatca
    39601 acacgaggaa ggtaaacgat acggaagtgg tctggttcct gccagttaaa gcctcgacca
    39661 tgaaccaaga gaaccttttc ctgcttcaag aaatcaagga caaactgctc atcatcatcg
    39721 atacggtaca tattgcggtc gatttttggg aagatataga gccccgcctt gggtttaacg
    39781 gcagacaaac ctggaatatc ttgaatggca ttatagatga aatttctttg ctcgtagatt
    39841 cgtccaccag gaagaagcaa ttcatcgact gattggtgac cccccaagga agtttgtacg
    39901 acttgttggg ccaaaacgtt agagcaaagg cgcatattgg acagcatatt gagcccttcg
    39961 atatagccct taacatgagt cttagggcca gacaagacca tccaacccac acggaaacct
    40021 gctatgcggt gggattttga cagaccattc atgctgacac agaagacatc tggtgccaag
    40081 ctcgccacag gcgtatgcac atgtccgtcc attaccatgc ggtcatagat ttcatccgca
    40141 aagataatca aatcgttttg acgggcaatc tcaataatct ccagcaagag tttcttagga
    40201 taaagggctc cagttgggtt atttggattg ataaggacga ttgccttggt attggaagtg
    40261 atttttgact tgatatcgtc aatatctggg taccattcaa cagcttcatc acagatatag
    40321 tgaacggcat ttcctccagc taggctgaca gccgccgtcc atagaggata gtctggcatt
    40381 ggcactaaga cctcatcccc attgtccaaa agcccctgca tggacatgac aatcaactca
    40441 ctgacaccat ttccaaggta aatatcatca atatctacgt ttgggaattt cttcagctgg
    40501 caatactgca tgatggcctt acgggctgag aaaattcctt tggagtcaga atagccttca
    40561 ctatcacgcg cattcataat caagtcatga atgacctcgt ctggcgctgt aaagccaaat
    40621 tctgctggat ttcctgtatt cagacgtaaa atcttttctc cattcgctcg catccgcatg
    40681 gcttcttcca atacaggacc acggatatca taagcaacat gctctaactt actagacttg
    40741 ttatattctt tcatcttgtt tcctcaattc atcaggatag taacattata ccactagaaa
    40801 gagaatgcga caagtttact gaaatgtgtt actagtttcg tatagaagaa aaaccttgct
    40861 aaaggcgagg ttaagaacgt agagatagca ggtattttgc aaagacacat cacataccaa
    40921 aagataaacc tagaaaaagc aagcctagaa aggagtcata aagaagatta aacatgagga
    40981 aaagccccca tatcatcaag taatcccaac gcccacttcg ttttgcaact agaaataaga
    41041 ttagatggta gagtacatga aagactaaaa atccaataaa acctggataa ataagcggta
    41101 ccaaactctc taattgccag atcatgatca cttctaccaa gactgaaact aggataattc
    41161 cataatacag gaaatttgat ttttgaaaag agtttttcat cattctccct tccttcactt
    41221 ctttcctgct atcctttctt ttattttatc atatatttat atagatttta agccctaata
    41281 ttcttttgaa aaatactttt tttgctttac ttctatagtg aaaaggttta caattatagt
    41341 aagaaaattt caggaggttt cattatggca caacgttacc aaaatatcat ggtcgcaatc
    41401 gatggttcta aggaagcgga cttggctttt gtcaagggag ttcattctgc tctacgaaac
    41461 gacgctaaac tcaccatcgt acatgtcatt gacatacgcg ctctccaaag cgtatccacc
    41521 tttgatgctg aagtttacga agaactccaa gtcgacgctg aaagtctgat gaaagagtac
    41581 gaaaaacgtg ctaaagatgc tggggtagca gatgttcata tcgtcattga aatgggaaat
    41641 ccaaagaccc tgctagcacg tactattcca gatgccgagg aagtggacct catcctcgtt
    41701 ggcgcaactg gtctcaacgc ctttgaacgc ctcttagtcg gctcttcatc tgaatacata
    41761 ctccgccatg ctaaggtcga tttgctggtt gtgagagaac aagaaaaaac cttataatca
    41821 caaagaaaag gagcccctag ctcctttttg tttacgattt atttctctct ttatggcgtt
    41881 cgtaagcctt gagctggcgc tgcagttcct ttttaatagc aggttctgga gcatattttt
    41941 cttcccaatt atctggtttt aagattttat gggtcactgg atcaaaatga gccttgccat
    42001 ctggaaaaat tttccccata ttggcctgat ggacaatatc aaaaatacgt tctgggtcca
    42061 cccccatcaa gacaaaactg ccgtaggtga agtaaagcgt gtcaatcaag gcatccactt
    42121 gccctatcaa atcttgctga gcaggtgtct tcttggctac tttacctgct gccttatcaa
    42181 gggcctgatg aagttgcgat acagcttgac caaaatcttc ttcagaagga ctggctgatc
    42241 gaacaaactc caccaattct tctattttaa aaccagccct atgggttgca ccctctaaat
    42301 cccaagctcg aggttcttct tgggttcgtt catccatcat gtggtggaag gtcttgacct
    42361 tattgaaatg atagtcacgg ctgacaaaga ctttttctga agacaaaaca ccaaaatgtt
    42421 ccaaggcctt gtggatccca tcttgttgat tgctagtggt aatgtgcttg gcagcttcct
    42481 tgacactgct actaccattt cccatagcga ccgacatacc gacgccagcc agcatttcaa
    42541 ggtcattatc tgagtcacca aaagccatga cttggttgag gtcaaagcca tattctttcc
    42601 caactcggcg aatgccttct aatttagaat ttccctgatt gatgacatcc gatgcaaaag
    42661 gattgctacg tgtcaatttc aagtcttcaa aatcagctgc cgccttctca gattcttctg
    42721 gtgtcatcag catcaaaact tggtagatag gctgattcat caggtgaagc aggtcctctt
    42781 ccttttgggg aacaaccttg ctgaccatgc gattaaaaga ctgactcacc gtccgagtta
    42841 aaacagaggg aacgaagcga ctaattcgtt gggaaaaaga acccagacca aaggacatga
    42901 ttttagaacc caacatggca tccttggtcc ctagagcaat ctccgtgccc tcttttttag
    42961 catagctaat tagatggcgc aaatgtaact tggaaatagg gctcgtgaac aagactctgt
    43021 ctttactaaa gatatactgg ccattatagg ttaccgcaaa atccagatcc aaatcgtcca
    43081 tcaattcctt aacaaaaaaa ggtcctcgcc ctgtcgctac gccaactagt accccttgtt
    43141 ctttgacaat cttaatcgcg tccttagtgg atttcaaaac actcttgcga ttgttgacca
    43201 aggttccatc gatatcaaaa aaaacagctt tgacttccat cctattccaa tctccccttt
    43261 tgtgatacaa tgattatacc acatttcaga aagagttagt aaatcatgcc taagaaaatc
    43321 cttgttttac atacgggtgg aactatttcc atgcaggccg atgcttctgg cgctgttgtg
    43381 acgagttcag ataatcccat gaaccatgtg tccaacccac ttgaaggaat ccaagtccac
    43441 gccttggact tttttaacct tccaagtccc catatcaaac ccaaacatat gctggtcctc
    43501 taccagaaaa ttaaagagga agcagataac tacgatggag tggtaatcac acacggaacc
    43561 gatactttag aggaaacagc ctatttcctt gataccatgg aagttcccca tatgcctatc
    43621 gttctaacag gagccatgcg tagctccaat gagctcggta gtgatggtgt ttataattac
    43681 ctaagtgctt tacgagtggc cagcgatgac agggctgctg acaaaggagt tttggtcgtt
    43741 atgaacgatg aaatccacgc tgccaagtat gtcaccaaaa cacatacgac taatgtcagc
    43801 accttccaga ctccaacaca tggccccctc ggtctcatca tgaaacagga aatcctctac
    43861 ttcaaaacag ctgaacctcg tgttcgcttt gaccttgatc acatacaagg tttagtccct
    43921 atcatctcgg cttatgctgg tatgacagat gagctgattg atatgctgga tttagaacac
    43981 ttggacggtt tgattatcca agccttcaga gctggtaata ttcccaaaga aacggctcaa
    44041 aaattagaaa gccttctgca aaaaggaatc ccagtcgctc tggtatcacg atgctttaac
    44101 ggtattgccg agcctgttta tgcctaccag ggtgggggcg tacagttgca aaaagcaggc
    44161 gttttctttg ttaaagaact caacgcccaa aaagcccgct tgaaactcct catcgccctc
    44221 aatgccggac taacaggaca ggctttgaaa gactatatgg aaggctaata ctcttcgaaa
    44281 atctctgcaa accacgtcac gtcgccttac cgtatgtatg gtt
//
LOCUS       DAVHSH010000011        43480 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000011 DAVHSH010000000
VERSION     DAVHSH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.011"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            156..1563
                     /locus_tag="VVR08_000722"
                     /pseudo
     CDS             156..1563
                     /locus_tag="VVR08_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            1581..2876
                     /locus_tag="VVR08_000723"
     CDS             1581..2876
                     /locus_tag="VVR08_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6074675.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            2881..3189
                     /locus_tag="VVR08_000724"
     CDS             2881..3189
                     /locus_tag="VVR08_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6074676.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            3186..3494
                     /locus_tag="VVR08_000725"
     CDS             3186..3494
                     /locus_tag="VVR08_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6074677.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(4283..6934)
                     /gene="adhE"
                     /locus_tag="VVR08_000726"
                     /gene_synonym="adhC"
     CDS             complement(4283..6934)
                     /gene="adhE"
                     /locus_tag="VVR08_000726"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU6074678.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRKLAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(7234..7644)
                     /locus_tag="VVR08_000727"
     CDS             complement(7234..7644)
                     /locus_tag="VVR08_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074679.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(7646..8074)
                     /locus_tag="VVR08_000728"
     CDS             complement(7646..8074)
                     /locus_tag="VVR08_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU6074680.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(8120..8419)
                     /gene="yajC"
                     /locus_tag="VVR08_000729"
     CDS             complement(8120..8419)
                     /gene="yajC"
                     /locus_tag="VVR08_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6074681.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(8536..10512)
                     /gene="tkt"
                     /locus_tag="VVR08_000730"
     CDS             complement(8536..10512)
                     /gene="tkt"
                     /locus_tag="VVR08_000730"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6074682.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMNEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEVHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(10625..11716)
                     /gene="ulaG"
                     /locus_tag="VVR08_000731"
     CDS             complement(10625..11716)
                     /gene="ulaG"
                     /locus_tag="VVR08_000731"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU6074683.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(11828..13501)
                     /locus_tag="VVR08_000732"
     CDS             complement(11828..13501)
                     /locus_tag="VVR08_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6074684.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            complement(13680..14384)
                     /locus_tag="VVR08_000733"
     CDS             complement(13680..14384)
                     /locus_tag="VVR08_000733"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU6074685.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(14386..15249)
                     /locus_tag="VVR08_000734"
     CDS             complement(14386..15249)
                     /locus_tag="VVR08_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU6074686.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(15253..15918)
                     /locus_tag="VVR08_000735"
     CDS             complement(15253..15918)
                     /locus_tag="VVR08_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU6074687.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            complement(15935..16420)
                     /locus_tag="VVR08_000736"
     CDS             complement(15935..16420)
                     /locus_tag="VVR08_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6074688.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(16497..16778)
                     /locus_tag="VVR08_000737"
     CDS             complement(16497..16778)
                     /locus_tag="VVR08_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6074689.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKIENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(16801..18258)
                     /locus_tag="VVR08_000738"
     CDS             complement(16801..18258)
                     /locus_tag="VVR08_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6074690.1"
                     /translation="MEVVSNVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(18387..19010)
                     /locus_tag="VVR08_000739"
     CDS             complement(18387..19010)
                     /locus_tag="VVR08_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU6074691.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMIALRLYGNPSDF
                     GISLEVSFIERKKDEQTLGKQAKVLEIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYQVTRG"
     gene            complement(19061..20047)
                     /locus_tag="VVR08_000740"
     CDS             complement(19061..20047)
                     /locus_tag="VVR08_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU6074692.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(20066..20890)
                     /locus_tag="VVR08_000741"
     CDS             complement(20066..20890)
                     /locus_tag="VVR08_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6074693.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(20865..21236)
                     /gene="rnpA"
                     /locus_tag="VVR08_000742"
     CDS             complement(20865..21236)
                     /gene="rnpA"
                     /locus_tag="VVR08_000742"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU6074694.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(21385..22575)
                     /locus_tag="VVR08_000743"
     CDS             complement(21385..22575)
                     /locus_tag="VVR08_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU6074695.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(22626..23579)
                     /locus_tag="VVR08_000744"
     CDS             complement(22626..23579)
                     /locus_tag="VVR08_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6074696.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(23640..24234)
                     /locus_tag="VVR08_000745"
                     /pseudo
     CDS             complement(23640..24234)
                     /locus_tag="VVR08_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(24371..24784)
                     /locus_tag="VVR08_000746"
     CDS             complement(24371..24784)
                     /locus_tag="VVR08_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6074697.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(24762..25223)
                     /locus_tag="VVR08_000747"
     CDS             complement(24762..25223)
                     /locus_tag="VVR08_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6074698.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            complement(25186..25446)
                     /locus_tag="VVR08_000748"
     CDS             complement(25186..25446)
                     /locus_tag="VVR08_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074699.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(25451..25855)
                     /locus_tag="VVR08_000749"
     CDS             complement(25451..25855)
                     /locus_tag="VVR08_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU6074700.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(25848..26174)
                     /gene="comGC"
                     /locus_tag="VVR08_000750"
     CDS             complement(25848..26174)
                     /gene="comGC"
                     /locus_tag="VVR08_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU6074701.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            complement(26176..27192)
                     /locus_tag="VVR08_000751"
     CDS             complement(26176..27192)
                     /locus_tag="VVR08_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU6074702.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LVMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(27140..28081)
                     /locus_tag="VVR08_000752"
     CDS             complement(27140..28081)
                     /locus_tag="VVR08_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU6074703.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(28157..28522)
                     /locus_tag="VVR08_000753"
     CDS             complement(28157..28522)
                     /locus_tag="VVR08_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU6074704.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(28673..29731)
                     /locus_tag="VVR08_000754"
     CDS             complement(28673..29731)
                     /locus_tag="VVR08_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU6074705.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(29894..31045)
                     /gene="nagA"
                     /locus_tag="VVR08_000755"
     CDS             complement(29894..31045)
                     /gene="nagA"
                     /locus_tag="VVR08_000755"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU6074706.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(31198..33015)
                     /locus_tag="VVR08_000756"
     CDS             complement(31198..33015)
                     /locus_tag="VVR08_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU6074707.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(33112..34254)
                     /gene="tgt"
                     /locus_tag="VVR08_000757"
     CDS             complement(33112..34254)
                     /gene="tgt"
                     /locus_tag="VVR08_000757"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU6074708.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQSLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            34384..35241
                     /locus_tag="VVR08_000758"
     CDS             34384..35241
                     /locus_tag="VVR08_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU6074709.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIHLLFYSSFLAKKFVTLHPEFP
                     SLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(35269..35913)
                     /gene="pcp"
                     /locus_tag="VVR08_000759"
     CDS             complement(35269..35913)
                     /gene="pcp"
                     /locus_tag="VVR08_000759"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6074710.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLETIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPI
                     RLDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRQTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(36020..36379)
                     /locus_tag="VVR08_000760"
     CDS             complement(36020..36379)
                     /locus_tag="VVR08_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU6074711.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            complement(36390..36728)
                     /locus_tag="VVR08_000761"
     CDS             complement(36390..36728)
                     /locus_tag="VVR08_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU6074712.1"
                     /translation="MTRYQILLFLLEHSLCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            complement(37242..38354)
                     /locus_tag="VVR08_000762"
     CDS             complement(37242..38354)
                     /locus_tag="VVR08_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6074713.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(38520..39140)
                     /locus_tag="VVR08_000763"
     CDS             complement(38520..39140)
                     /locus_tag="VVR08_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6074714.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(39144..40424)
                     /locus_tag="VVR08_000764"
     CDS             complement(39144..40424)
                     /locus_tag="VVR08_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6074715.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAVISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERAVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPVFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(40485..41969)
                     /locus_tag="VVR08_000765"
     CDS             complement(40485..41969)
                     /locus_tag="VVR08_000765"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU6074716.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            complement(42045..43322)
                     /locus_tag="VVR08_000766"
     CDS             complement(42045..43322)
                     /locus_tag="VVR08_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU6074717.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
BASE COUNT        12932 a         9508 c         7777 g        13263 t
ORIGIN      
        1 aatagtagta taacaaaaat attctaatag tagtataaca aagttcaaga aatgaggcaa
       61 acacaagata tgtatcaaca atttttaaaa atgtctagac aaattttaaa attatgctat
      121 actttatgta taggataata gaaaggaggt tgagcatgaa aaagaagtta gtatttccta
      181 atctgttttg gtggggagct gcttctagcg gacctcagac agaaggtcaa tatggaaaag
      241 tacatgaaaa tgtgatggac tactggttca aaacgcatcc agaagatttt ttcgataatg
      301 tcggacctct tgtagccagt aacttttttc atacttacac cgaagatttc cacttgatga
      361 aggaaattgg agttaattct ttccgcactt ccatccaatg gagtcgactc atcaagaatt
      421 tagagacagg tgagcctgat ccaaaaggta ttgctttcta caatgccatc attgaagaag
      481 ctaaaaagaa ccagatggat cttgtgatga atttacatca ttttgattta ccagtggaac
      541 ttcttcaaaa atacggtggt tgggaaagca aacatgtagt ggagttattc gtgaagtttg
      601 ccaagactgc tttcacatgc tttggagata aggttcatta ctggacaact ttcaatgagc
      661 caatggtcat tccagaagca ggatacttat atgctttcca ttatccaaat ctaaaaggaa
      721 agggaaaaga ggccgtacaa gtcatctata atctaaacct tgctagtgca aaagtgattc
      781 aactatatcg ctcattagga cttgatggaa agattgggat tattttaaac ttgacacctg
      841 cttatccaag aagtaattct ccagaagact tagaagcaag tcgatttaca gatgacttct
      901 ttaacaaagt cttcttgaat ccagctgtta aaggaacttt cccagaaaga ttggtaaaac
      961 agctagagag atggcgtgtt atggagtcat accgaaaaag agcttcaact gatgaaatca
     1021 aatacggttg attttcttgg agtaaactac taccatccaa aacgtgttca agcacaagca
     1081 aatcctgagg aatatcagac gccctggatg ccagatcaat acttcaaaga gtatgaatgg
     1141 ccggagcgtc gcatgaatcc atatcgtggt tgggaaattt ttccgaaagc catttatgat
     1201 attgctatga ttgtgaagga agaatatgat aatattccat ggtttatcag tgaaaacgga
     1261 atgggtgttg aaaacgaagc acggtttatc ggtgaaaatg gagttatcga tgacgtgtat
     1321 cgtattgaat tttatgaaga acatttaaga tggctacata aagccattga agagggaagt
     1381 cactgttttg gataccacgc ttggaccgca tttgattgct ggtcttggaa taatgcatat
     1441 aagaatcgtt acggatttat ctccgttgat ttagaaacgc aaaagagaac catcaagagc
     1501 tcaggaagat ggtatcgcaa agtaagtgac aataacggtt ttgaagtaga aattgaggag
     1561 taaagagagg agatattcat atgaaaaact caaaatttat agaccaattt gccacctttg
     1621 ctggtaaact agggaaccaa attcatttaa aaaccctaag agatgcattc gtaacagtaa
     1681 tgccattata tattttggca ggtttaatcg ttcttttgaa caacacggta tttaagtgga
     1741 ttttccaagg ggatacatta acaagattcc aatattgggg aataacaatt gcaaacggta
     1801 ctttaagtat ttcaggtatg attattgctg taatggttgg ttatttctta gctaaaaaca
     1861 gagatttcga aaacccgtta gcagcatcaa tgctatcatt agtttcttta attgtgatga
     1921 tgccaaatac agtttctgta gttcctgacg gagcaaaaga tgcggtaaac atttcaggtg
     1981 ttctttcatt caacaacaca ggtacaggcg caatgttcgc cggggttatc gtagcgatta
     2041 ttgcaacaga attattcatt gaattatcaa acgttaaagc tttacaaatg aaccttggtg
     2101 aaaatattcc accagctgtt agtagatcat ttagcgtatt acttccagtc atgaccgtca
     2161 tctccttatt tggggttgtt tcagcattat tattcaatat aactggaatg aacttaatct
     2221 caatcattac aatctttatt caagaaccaa ttcgtcatat tggtacaagc ttaatcgggg
     2281 tcattattat ttactcttta ggaaatatgt tatggctatt tggtattcac caagcagtta
     2341 tttacagtgc catcctagaa ccattactat taattaacat tactgaaaac atcactgcag
     2401 caaataatgg acaagccatt ccacacatca tcaacctatc acaaatacaa acattcgctt
     2461 taatgggtgg tagtggatct acattatgtt tattaatagc aacattctta gtgagtcgca
     2521 atgctgtctc taaaaacgtg gctaaattat cttttggacc tggtatcttc aatatcaatg
     2581 aaccagtatt attcggttac ccaatcgttt ataacatttc attagctatt ccatttatca
     2641 cagttccagt ccttggtatt ttaatcagct acttagcaac agttacagga ttcatgagtc
     2701 ctgcatttat acaagttcct tggactacac cagtattctt aaatgcatgg ttagcaacag
     2761 caggggacgt gagagcagtt ctagttcaat tcatcatctt tgcacttgga gttcttctat
     2821 acattccatt tatcaaagtt aatgacaaag ttgttgagca agaaatggaa ggttaagatt
     2881 atgaaacaaa ttttattagt atgtaatgcg ggaatgtcga caagtatgct tgttaaaaaa
     2941 atgcaacaaa gtgcgactga acgtgggatt gaaatttcta tccaagcaaa atcaatgaca
     3001 gaagctaaaa agaatatcca tgaagcagat gtcattctaa ttgggccaca aattcgttat
     3061 gagttacttg ctgtgaaaga aattgcagga aatatccctg tagataccat tgatatgcgg
     3121 gattacggaa tgatgaatgg agcaaaagtg ctggaacaag cacttgcatg gataggagaa
     3181 ataagatgac agaagaaatg gaatatatct gttttcagct cattgccaat agtggagcag
     3241 ccaaatcatc ctttattgaa gccatccaac tagctaaggc aggaaattta aaagaagcga
     3301 aaattaaagt tgaagaagcg gaagactcct tagtagaagc gcacaagatt cactctaatc
     3361 tcatacaaaa agaagctact ggagaaaaaa taggattctc cttgctattt atgcatgcag
     3421 aagaccaaat ggcttcaaca gagattattc agttgctatc taaagaattc atcgatctct
     3481 atcaaaataa ataggaacac tgtcattccc atctgtcttt attaataacg actacattgt
     3541 aggaacctcc aaaagttgga caaaatgatt gaaaggattg gatcctgcat tacacaagat
     3601 ccaatccttt tcttttactc tagtttttat aatatgttga atctagaata gtccactgca
     3661 gtttctaaaa aattgctgga aatagatgtt aagctccaat ttatttgttt atatcttatt
     3721 tcagtttact atactagctt attattctag tgaaaaattg aatgagccac tatttattta
     3781 atatgtatga tgagggaatg actcaaaaac ttcttgtcga tataagaata tctgagatag
     3841 tattttaaaa cgaaaggatt ataaaagctc atttccttcg cacttatttt atagagatct
     3901 atcattatac tctttagaaa tcaaaaagca acacaccttg tcatcgtttt ctcgtttgct
     3961 ctttgatttt aattgggcct tagtaaatac tactcttaaa ttaaactata gtgaattgaa
     4021 ataagatgtg aacaactcta tcagaaaagt aaaattaatt tctataaatg ttttagcagc
     4081 agatgtgtac tattctagtt tcaacctact atatattttg tttctattct agtttttcaa
     4141 aaagggcaaa aaggcctcaa catcataaaa aggcatccta tcaggtattc aaaaaccttg
     4201 ataggatgcc ttttatcata gaaaaattac tggatctttc cctcaaattg agtttttgtc
     4261 ttgcttctag actgataaac aattatttac ggcgtcctgg tctttctttg tagccatagt
     4321 atgcatcttc gatgatttct tgcatatggt ctaccattgg aagacgtggg ttagctggtg
     4381 aacattggtc ttcataagcc aggaaggcta atttacgaga atgttctttc cattcttttt
     4441 cgtcaattcc ttggtctcta aaattcattt ggatcccaat acgttcaccg agttcgtaga
     4501 cagcttttgc gtaagattca accccttctt ctggagtaga agctggaagt ccaagcatgc
     4561 gtgcgatatc ttggtatttt tcatctgcac ggtagtagtt gtacttaggc catgttgctg
     4621 tcttagctgg acgtgtaccg ttgtaacgga taacgtacgg aagcaagatg gcatttgtac
     4681 gtccgtgaac tgtgtggaat tgcgcaccaa tcttatgggc cattgagtga gaaataccta
     4741 ggaaggcatt ggcaaaggcc ataccagcga ttgttgaagc gttatgcatt ttctcacgtg
     4801 agtggaagtc tgcattctta actgagcttt cgagattttc aaagaccaat ttaatagctt
     4861 gaagtgctaa accatcagtg tagtcactag ccatttgtga tacgtatgct tctgtcgcgt
     4921 gagtcaatac gtccatacca gtatcagcag caacaaatcc tggaactgtc aataccaaag
     4981 cagggtctac aattgccaca gttggtgtca atgagtagtc agcgattggg tatttacggt
     5041 tgtttgcttt atcagagata acggcaaatg gtgttacttc agatcctgta ccagatgtag
     5101 ttggaatcgc gatgaattta gtcttcttac caagcaatgg gaacttgaag gcacgtttac
     5161 ggatatccat gaatttttgg acaaggtcac ggaagtccac ttctggttgc tcgtagaaaa
     5221 gccacattac tttggcagca tccattggag acccaccacc gagtgcgatg atggtatctg
     5281 gtttgaaggc acgcataatc tcagtaccac ggtttacagt tgtgatatct ggatccggtt
     5341 ctacatccgc aaagatttgg taaacaacct tattgcgacg aaggtccagt tgttcgatga
     5401 tacgatcaag gaaaccaagc tctaccatgg catggtcagt aacgatcatg acacgttcaa
     5461 cgtcacgaca tttttgaagg tattgaattg aatcacgttc aaagtatgtt tttgaaggaa
     5521 gtttcatcca ttgcatgtta tttctccgtc ttccgacttt tttgatattc aagaggttaa
     5581 tggcactaac gttatcccca actgagtttc gtccgtaaga accacatcca agtgtcaatg
     5641 atggcaagaa ggcattgtaa acgtccccga taccaccaaa agtagaaggt gagttacaga
     5701 taacacgaat agctttaaca gctttaccaa attctttagt caattcttcg tcagctgtgt
     5761 ggatagctgc tgagtgtcca agaccgttaa attcaaccat ttgacgagcc ttagtaatac
     5821 catcttcacg gctttcagat ttcaaaactg caataactgg tgacaatttt tcacgagtca
     5881 atggctcatt ttcgccaact tctttacatt ctgcagcaag aatgtttgtt ccttctggaa
     5941 ctgtaaatcc tgcttgttct gcaatccaag ttgctggttt accaacgatg tcagcgttca
     6001 attttgcacc agcacagttt ttgctgtttg ctttgacgcc gaagcagaac tcttcaagaa
     6061 gagctttttc ttttttgttt acaaagtaag tgtggtaaga tttgaactct gctacaaatt
     6121 catcgtaaat ttctttatca atgataactg cttgttcaga tgcacagacc ataccgttat
     6181 caaatgattt agacatgacg atatcgtgtg ctgcttgacg aatgtttgct gatttttcaa
     6241 cataagctgg aacgtttccg gcacctaccc caagagctgg tttaccacat gaataagccg
     6301 ccttaaccat ggcattacca cctgttgcaa ggattgtcgc aacaccttcg tggttcataa
     6361 gggcacttgt tgcttccata gatggttgag taatccattg cacacagttt tcaggagcac
     6421 cagctgcgat agctgcatcg cggacgatac gagctgcatg agcagatgat tcttgtgctg
     6481 atggatggaa ggcaaagacg attgggttac gtgtcttcaa tgaaatcaat gatttgaaga
     6541 ttgctgttga tgttgggttt gttgttggag taataccaca aacaacacca actggttcag
     6601 caataagagt caatcctgtt acatcgtctt cttcgataac gccaactgtc ttagtgtgac
     6661 gcatgttgtt tactacgtgt tcacaggcaa acaagttctt agttgcttta tcttcaaata
     6721 caccacgtcc tgtttcttca aaggcatgta aagccaattc tccgtgggca tccaaagctg
     6781 ctactgatgc tttggcaacg atgtagtcaa cttgctcttg atccaattta cgcatttctt
     6841 caagggcaac tagagctttt tgaaccaact catctacgtg tttttcagca acgagtttct
     6901 tttcctctgg tgtcacagtt tttttatcag ccatattttc ctccacagct ttcaaggatc
     6961 gatatccttt gttaattttt tcacaagttt attataacgt attatttcaa ctttgtaaac
     7021 agtttcataa acatttcaca aagaattttt aaactcttgt gaaacttttc tcattttctt
     7081 ttcttatcag gttttatctt tgaagtttgt gaaatttatt tcaaatattt tttatttcac
     7141 aaacttgctt ggaagaggga tttggaaaga aagagattta caggtaagcg cttaccttgt
     7201 gattctaata atacctcctt tgataaggag gctttatttt tgttgaaaaa cgccttgttt
     7261 aaaagttcct tcataaacga cttcttgttc tgttgttagt ttcccttttc cttcagcctg
     7321 accatttaca aaatcacctt cgtaggtcca gccttcttta gattgaaagg taccttttcc
     7381 gttgaaggct ccattgttga agccacctgt atattggtct ccattttgga aggtaatggt
     7441 accttggcca ttcattttac cacggacaag actgccatca taaacaatcg ttccattatc
     7501 gagttttaag acaccttttc ctggaatatt tagaaaaaag acgagtacag cacagaaaac
     7561 aatggtaact actgccaaaa gctctaaacg tggacgagtc agatagacac gatacttttc
     7621 gtaaaaattc gtaagatttt ccaccttaac tctccttttc taaacgttct aaccaagctt
     7681 gacagccctc ttgaacacgt cgataggttt cttcaaaatc tcctgtatac caagggtctg
     7741 gaacactttc agatgaaaat gagtaaatct tatcttgaca gtctactgga cacatctgac
     7801 gtaagtcaga aatatttgaa gcgtccattc cgataatata atcaaaggct tcaaaatctt
     7861 ccttactaat ctgaagcgat gtcttgttct tgtcataagg aatctcatac tcttgaaaaa
     7921 ttccctgagt ccccttatga atcggattgc catgttccca agaggaagtt gctcgacttt
     7981 ggatttcgta gttatctgtc attgatttca taacaaactc ggccataggg ctacggcaaa
     8041 tatttcccag acagacaaag actaattttt tcatcccatt tcctttcttt tatagaaaac
     8101 gggagttcgt gatcccgtct tatttttcaa ttgcgccttc tagtgaagct gtttctttca
     8161 gcggtaatac tgtcttgata gcagctagtt caaaagtcaa gtaaactcca tctacgtcaa
     8221 gaactattgt tcccttctcc gtatctactt catcgactgt tccataaagt ccaccgattg
     8281 taatcacttc atagcctttt tgtagtttat ttaagctttc catacgcttt tgagcttgtt
     8341 tcttttgaga acgttgcata aagaacatca aggccatcat acctacaagc atgattaaaa
     8401 aagtaatatt tggattcatt gttttctcct ttgtctttta cataggacta ctatatcaaa
     8461 tttcagctac ttttacaaga ttgtacctta cttttctggt aagaaaaacc agagcttacg
     8521 ccctgatttt taggattatt tcaaatttcg aacaactttt acaagatttt cgacagtaaa
     8581 gccatattct gccaatactt ttggtgctgg ggcagaggct ccgaaggtat caatacctag
     8641 aacggcacca tcgagaccaa catatttgta ccagttttga cttgcaccca tttcgactgc
     8701 aacacgacgg cggactgcat ttggaagaat ttcttccttg taagctgcat cttgtttatc
     8761 aaagacatct gtagatggca tgctgactac gcggattttt tcgccttgac tagccaattc
     8821 tttagcagct gagacagcaa gattaacctc tgaacctgtc gcaatcaaga tggtatcaaa
     8881 gtcggctgca ttttcatata caacataagc acctttagca accttgtcga agtctgttcc
     8941 atcttcaaca gtcaagtttt gacgtgtcaa gacaagggca gttggtgttt tctcacttgt
     9001 cactgcaagg taccaagctg cttgcgtttc acgcgcatct gctggacgga aaacatttag
     9061 atttggcata gcacgaagac ctgctaaatg ctcaactggt tcgtgagtcg gaccatcttc
     9121 cccaactgcg attgaatcat gggtaaagac ataagtcaca ggaagtcctt gtaaggctga
     9181 caagcggaca gctgccttca catagtcaga gaagacgaag aaagttccac cgtatacacg
     9241 aagtccacca tgaagggcca tcccgttcaa gattgttccc attgcaaatt cacgaacacc
     9301 aaactgaatg ttacgattca agcgattggc atcgtcttga agtccatccg tcttgatata
     9361 agtcatgttt gagtgagcaa ggtcagctga tccacctagg aaggttggta atttagctgc
     9421 cacaacattc aaggcatctt gacttgaatt acgagttgct tgagaaaaac cattttctaa
     9481 agctgggaag tctgctggag tcacttcgac tggatcacgt ccgtcgatga tggcttctac
     9541 ttctgcagcc agttctggat gaacttcttt ataatctgca actaatttag tccaagcttg
     9601 ataagctgat gcgccacggt ctgcaacatg ttctttgaaa tcagcatata cttgttctgg
     9661 aatttcaaat ggttcgtagt cccaaccgag ggcttggcga gttgatgcag tttcatctgc
     9721 tccaagaggg gcgccgtgta cagcattagt tccttgtttg tttggagaac cgtatccaat
     9781 aaccgtcttc acttcaatca aagatggctt gcctgaagct tttgctgttt cgatagcagc
     9841 atggatggct tccaagtctg ttccattttc aaccaaggca gtatgccaac cgtaggcatt
     9901 gtaacggtca cgaacacttt ctgtaaagga atcctttgtc tcaccatcca agttgatatc
     9961 atttgaatca taaagaacaa ccaacttatc aagtttttgc aaacctgcgt atgaagctgc
    10021 ctcgcttgag acaccttcca tcaagtctcc gtctccacag ataacgtaag tatagtggtc
    10081 aaagatattg tagccttcac ggttatattt ggctgccaag aaacgttctg cttgggcaaa
    10141 accagtagca gttgaaatcc cttgccctag aggacctgtc gtagcatcaa tccctgccgt
    10201 atgaccaaat tctgggtgac ctggtgtttt tgaaccccat tgacggaagc tcttaatctc
    10261 attcatgctg acatcttcaa aaccagaaag gtgaagaaga gcataaagga gcattgaacc
    10321 atgacctgct gaaagaataa agcggtcgcg gttaatccaa tttggttgag ctggattgat
    10381 atgaagttgt tttgtaaaga ggctgtaagc catcggagcc gctcccataa ccacacctgg
    10441 atgacctgag ttggctttat taatggcgtc aatacctaga aaacgaattg cattaacaga
    10501 tagatttgac atagaatttc ctttctattg aggtgattat tgaatcacac attctatttt
    10561 actattatat gaaaattatc cgtatcatgc aacatacgga taacctccaa agaatatttt
    10621 tatattatag caaagcttta aattgaatgt tagagtcttg ttcaaaacaa tcatcaaaac
    10681 cacgtggatg atggtattct actaagtgtt gatcttgagg ataagtgtac ttaccgccaa
    10741 cttcccagat aaatggatgg aaatcgtatt gcaagcgatc ttttcgcatt ttccaaagtt
    10801 ctagaatctc attagtagaa gccatgaagt tagaccagat atcatagtga actgggataa
    10861 tgactttggt acgcagattt tctgccatac gaagaaggtc gatagatgtc attttgtctt
    10921 ggatacctac cggattttca ccatagttat tcaaagcaac atcaatttta aagtctttac
    10981 catgttttgc aaaatagttt gagaagtgag aatctgcacc atgatagatg gttccacctg
    11041 gtgtttcaaa gatatagtta acagcctttt gagccatttc ttcatctgta acagccaagc
    11101 cagcaagttc accgcctgtc tcatcagcac cgttcactgg gagagttacc aagcaagtac
    11161 ggtcaaatga ttctactgca tgaatcttca tatcttttaa ttcgatagtg tcacctggtt
    11221 taacaacgat gatacgttct tttggaacac cccatccttc ccagattcgt ccacagtggt
    11281 aaggaccgat aaacttaaca tgctctaact taggattgtt gagaattgct gcagctgtgt
    11341 atgggtcgat atgatcactg tggaagtgtg aaactaagta atagtctagt tcgttgatag
    11401 caaatggatc gataaccatt ggctgaacac gcaagtttgg ttgcaactta cgaacacctg
    11461 ccatatttgc catttggtgc ccacgaacca tatctttcac ttttttggtt gattttccac
    11521 ggtttgacca aaggtccatg acaacgttag caccagctgg tgtcttaatc caagtaccac
    11581 agttgcctag ccaccacatg gcaaagttgc cttcaggtac gacttcttct tcgatttctt
    11641 cgttcaacca tgttccccac tctgggaaag tggctaaaat ccatgactct cttgtaattt
    11701 ctttgacgtt tggcatatgt tgcctccttt ggatataatt gttatctttg agattagtat
    11761 accacccttc aaaacactaa aaaagaccaa gaaaaacaca ggtttgtgtt catcattgga
    11821 ctgtccttca aatatcttcc aaaaaagctt gaactactat ttcttgattt ataagtgttt
    11881 gaacctcttc ttggaactta ctagccaact tgctgtctac aatataagac gaaataagac
    11941 tagaaagatt ttcactgaaa cttttgctct tattacgaaa tatattgtgt ttaagatagt
    12001 ctagcatttt caaaatatct tctgcttcaa ggataggatt aacccttaaa atcggaaatc
    12061 tgctatccaa atcatcatta gtagtaatca ctacatcaac ttgtgcaata tcttccacac
    12121 tcttaaattg ttctgttgta aatacagtgt caatttgctc atttggaaaa taaagtttgc
    12181 attgtttcag caaaagtctc gaaaccgcaa caccttcatc acaaacgaga taaacttttt
    12241 tcatattttt ttgagacgat ggtgtatact ttaaaaatcc tccaatatga atcgtcaaat
    12301 aggcaatatc atcgtctgtt agccgaataa accatgctcc ttctaaaatt tccgcagatt
    12361 ttctagtgac taaaaataat tctccatact tggatcgaat ttgttttgtt agaggatttt
    12421 tagaaaaaat accgtaagtc tttctaaata acaaggcttt acagtggatc atcaaatttc
    12481 gtaacaaatc atccttgttc tcaatctcca ttcggatttg tgattcaaaa taccagataa
    12541 attcttctaa agcaagtttt aattgccgaa aatcatcact ttctgcatga atatccaaat
    12601 ctttacgata ggagaggagg agaacagcta caagagaaac ttcaagtcct gacaaagaaa
    12661 tttcaaactt ttgaaacaac cgttctccta atttcttaga cacctgatac tctattcttt
    12721 ttcttatcaa agaaaactct ttctctatat cctgatgtct ttcttgatac tgttcaacat
    12781 tatgacagct taacagcaaa taaggtagaa cctgcaacat aaaagttatt tcatgatgat
    12841 ttattttctt ccctaaatct tgttcaacta aaggaacctg ttccttaaaa aattggttca
    12901 tttcaacaga aagcaaacac tcatcatcta acctctcttt catcttatct tctaaaatag
    12961 atacaaaagt ggcattttct tccataaaaa tatgatatag aagcgattga agatactgaa
    13021 ttttattaag agggtgggca tgaaggtggt atccctgtga cttgctcact tgcaaggtca
    13081 cctgatattg ttccaaagtt agttgataac gaatgctatt caaatcattg agaacagtat
    13141 tcctagatac ctctgttaac tctatcaatt tttcaatcgt aatacgttct ttagaaatac
    13201 ctatccatag taacattatc atcatacgtt catgcgcact catgatataa tcgtacgaat
    13261 ctacttccga taatagttta caacaagcat ctctctgctc ttccgttaag tgaataccaa
    13321 ttcgtggaat actaatgatg tgaagcgcct cgtcaaccag agcagcattg attttgtcaa
    13381 tgtgataata aattttcctt cttgactctt tcaaatcttt cgaaatcgcc ataatcgttt
    13441 tggacgtttc ttgatccatc aaatattgaa gcaaatcaca acttgcctta tccagtacca
    13501 tattaaaaaa tcccccaaat ctattgatat cacagcaatt ctttttattt taccatatat
    13561 atatcaagcg ctatttctaa aaaatctttc aaaattactt caactccaac tttactctca
    13621 ataaaaatca aatgtaaaaa gaggagctaa atttatcttt ttctcctcct tcatcgttct
    13681 tacttttgac cataataagc atttggtcca tgtttacgtt ggtagtgttt ttctagtatg
    13741 tactggggag caggtccaac tcttggattg atttgttctg taaagcgatt catctttgat
    13801 acttcctcta gtacgacaga gtgataaaca gcattctctg gatttttgcc ccaggtgaat
    13861 ggaccgtgat tgcgtacaac aattcctggt acttcaaccg ggttaagtcc gcgatgttca
    13921 aactcttcta cgataaccag gccagtatct ttttcatagg ccacttctac ttcgtccttg
    13981 gtcaaactac gggcgcaagg gattgaaccg tagaaataat ctgcatgggt tgttccgtag
    14041 aaaggaatat cacgacctgc ctgagcccaa ccaacagctt ctgtcgaatg ggtgtgaacc
    14101 acactaccaa tttctgacca agtcttatat aattgcacat gagttgggag gtcggaagat
    14161 ggtcttaaat ccccttctag gatcttacca tctagatcag tcactaccat gttttcaggt
    14221 gtcaattcgt cataatccac gcctgatggt ttgataacaa tgacaccgag ttcgcgattg
    14281 acttcagata cattccccca ggtaaatttg acaagtccat gttttggcaa tgattgattg
    14341 gcatcacaga ctcgtttacg catagcattg attacttgat tcatcttaca tcaaacctgc
    14401 tttcttaatg agtggataga gaaaagcttg cgcctcttga atggctgcgc gtgtttcttc
    14461 tactgtttca caattttcag accacatttc gattaggaaa ggtccattat aattggtttc
    14521 ctttaaaata tcgaaagctt cttcccattt gacacaacct tgcccgaaag gtacatctcg
    14581 gaactggccc tttgaacttt ctgtcactgc ataagtatcc ttgagatgga gagctgcgat
    14641 ggcatgatga ccaagataaa actcactata gatatcatta tgccatgcag acacattacc
    14701 aatatctgga tatacaaaga ggaagggaga gtcaatctct ttttctatag ccaaatattt
    14761 ttcgatgcta ctgatgaaag gatcatccat aatttcaata gcaagtacca cctgagcttc
    14821 ttcagcccag tcacaggctt ttctcaaatt tttgataaaa cgttggcgtg tctggggtga
    14881 cttttcctca tagtaaacat cgtaaccagc taattgaatc gtacgaactc ccaagtcttg
    14941 agctaattcg atacattttt tcatgagttc tagagatttt tcctctagaa ctgaatcttt
    15001 tgatcccaat gggtagcgac gatggcctga aaaacagata gaaggaatac gaacaccagt
    15061 ttcatagatt gctttgacaa cttccaagcg ttcttcctta ctccagtcaa gtcttgctaa
    15121 acgctcgtca cgttcgtcaa tagacatctc gataaaatca aagcctaact ccttggcaaa
    15181 atttaaacgt tctagccaag taaagtgtgt tggggttgcc ttttcataaa ttccaattgg
    15241 acgtaccatg atttaccccc aaattcgttt gatttcatcc ttgaaggcac gcgctgctcc
    15301 tgctggatcc gcagcctctg taattccacg acctgcgata aaggtaaaga tatcaacacc
    15361 ttcaaagagt ttgagagtat ctacatctag accacctgtt acagatacac ggaagcccat
    15421 gtcaatgagt tttttaacct tattaaggtc tttttcaccc caagtttcac cagcaagaag
    15481 agcatcacga gattggtgat aaatagcttg tgagatacct gcatctagcc aaagctgagc
    15541 ttgttcaaaa gtccaatcgc cataaagctc gatctggatt tcgcctcgtt ctcctcgttc
    15601 agtcttgata gcctttagag ctgcttccat agtagggatg gttgcacaac agatacaagt
    15661 catccagtct gctccacgaa ccgcattatt tttagcaact gttccaccag catcagcaca
    15721 ttttgtgtct gccacaataa tcttatctgg gaaaaggcta cgcaagactt cagccagttc
    15781 acttccaact tgaagcaagc aaacagttcc agcttcgata atatctactt cctgaccaac
    15841 agaaacagct gctttaatcg ctccttgcaa gtctgaatgg tctaatgcaa cttgtaaatt
    15901 aggtattctt tttgtcattt ctttattcct ctttctaact ttccaaatcc aatccttcga
    15961 gataagggct atccttagat tcttcaatca tagccaagac atcttcttta gtctggcaag
    16021 cctgtaaacg tgcaatagaa tcttctaatt caaacagggc aataatttgt ggaatggcta
    16081 cacttgtgtg aatttttgaa cttgttgctg ctagtgccaa caaaacagat acctctttcc
    16141 catctgaaaa tacaacagga ttttgtaagg taatcaatga aaaggcatca ctttgcacac
    16201 cagcttcagg tctagcgtgg ggcatagcca tacctggcat caagatatag taaggcccat
    16261 actcttcagt cgattcaatg atagcatcgt aatactctgg caaaattgcc ccactttcaa
    16321 ttaagggatc tactgctacc ttgactgctt ctttccaatt gttagcctct aaacctagtc
    16381 ggatcgagtc attgtcaatt aaagcttgtt ttaaattcat atctgcctcc tttatttaaa
    16441 gagggagaag gacagaaacg ataactctca gtttctgtcc agccccctcc aaccttttac
    16501 tgtagtgctt gactgagttt ttcggtgatt tctttatcat ccatcaagtt atcaagccca
    16561 attaacttcc cattagttcg cccttccaat tcttgaatca aatgaagaga agcgattacg
    16621 atgtcatatc ctactgctaa acctttagct tcaccgacac tgcatgaatt gactgtaaaa
    16681 tctgtttgat taagcttacg gagagcattt tcaatcttca tcttgataac cattgatgaa
    16741 cccattccat ttccgcacgc tgctaatact ttaaccattt tatttctcct tttctagata
    16801 ctaagcttct tcttgaactt caccgttgta atatttctct ttatcttttg ctttggcaaa
    16861 ttgaagttga ggaataacaa gcaagaagag acacacaagt acataaccaa caataccaag
    16921 gtatttgaag atatatccaa atccaagcca tgggaattca aagtcgatat ttccatggta
    16981 gccaccataa gatgccaaat cgagaagggc cacacaaaga gctcctagag caacttgaag
    17041 gacacctgat ataaaggaaa ggataacagc cgctttccat ccgccgcgtt tatcagcgta
    17101 gaccgcaatg gctgcattgt caaagaacac tggtacaaat cctgtaataa taagaatcgg
    17161 atttttaaag acgatgagca agacaattgt aatcaattga ccaatcaaac caaaggtaaa
    17221 tcctgacaag acagcatttg gagaaccaaa tccataagaa gctgcaacgt caaccgctgg
    17281 gaatgaacct ggcaacaatt tgtttgaaat accttggaag gcgtttgtca actcagatac
    17341 gaacattcgg acaccttgca tcaaaacgaa caagtaaact gagaaggtaa aggctgtttg
    17401 gataatgtac ataaagaaat cttgtttagc aggattgaat agagttcctg aagtgatgac
    17461 ttctttatta gacataatgt ctggacccaa gattaaaaga atggctccga agaatacgag
    17521 catcaaggta gcagatgcaa caactgtatc gtggaagatt gagaggaact taggtaattt
    17581 aagattgtct aaactttctt ctttcttacc aaagcgtcct gctactttat ctacaaacca
    17641 gattgcaaat tgctgttggt gaccaatcgc aaatccgcca ccaccagtca agcgttgagt
    17701 tgcctcaaca gtcatatttg aactaactgc ccagtaaagt ccacagatga taccaatcgc
    17761 tgctgtaccg taagcattgc gcaattgtgg tactaagaat agaaccataa gagatactgt
    17821 tgcagcttgt tgtaccatga tgtgaccagt aataaagagg gttcttacct tcgtaatctt
    17881 tcgaagagct acgagcaaga tatttattcc aaaaccaatc aatagagctg tagttgcagt
    17941 tccaacaaaa tctggaaact ctgctgcaat tttgttgttt gctgcagcaa gtccaaagta
    18001 agggtcgata accgctgcac caatttggaa tttgtagtta agagctgcta agattggacg
    18061 aaaggttgta accaaaccac cagcacccac gttaagcaac atatacccta ctgttgcttt
    18121 aacaaaccct gaaaaaacgt catgggcagg ttttttcaaa agtgcatatc ctatcaacac
    18181 caataaacct acgaaaaatg cgggattctg caaaatattg ctagaaaacc aatttagaac
    18241 atttgaaacg acttccataa ttgttctcct tttgaattgt ttttgtaagt ttattatata
    18301 atgcgaaagc gcaaacaaaa agaccaagaa ttacacagcg gactgttcac tcttggactg
    18361 taatcttata ataattgact gacacgttat cctctagtca cctgataata gggaagaatt
    18421 ttagaataag acttcaataa gccttctacg atttcttctt cagacgaatt ttctgtcata
    18481 ggaacatcta ccttcactaa aacttttcga acttcttgac ttctcacctt ctcgcgtaaa
    18541 gtacgacgct tttcttcatt cgcctcccac cgttgacttt gaccattaga gtaggttaga
    18601 taataaatcc ctttaacggt tggaatttct aaaactttgg cctgcttgcc cagtgtttgc
    18661 tcatccttct tacgttcgat gaaactgact tctaaggaaa taccaaaatc agaaggattt
    18721 ccatacaaac gcaaggctat cataggttct gtcacttgtc cgtctctctg tagataaacc
    18781 caaaaatgtg gtctcaaacg ctgggcctga ttcatccact gactagtctg ttggagttgc
    18841 cattctggat ggcttgcttg aaaggctttg gccagttctg taaaagcctt tcgagcctct
    18901 tgtcctttgt ggcggaatgc cagcatcttc tctcgctctg ctcccgcttt atcaggatta
    18961 cggtactgca aaccagcaaa gtctaaatag tctcttatct tattcaacat cagtttaacc
    19021 tcctctagct agcaaaaaat caggtcaacc ctgattttac ttattctgta tctacaacga
    19081 catagcgatt tggctcatca ccttcagagt aactggtcac gccatccata cgtgaaataa
    19141 tacggtggat aatcttgcgt tcactattcg acattggatc tgtttgatga ctacgtcctt
    19201 cttctaaaac acgaatcgcc aatttttgcg cataggtctg caagacttct gcacggtgtt
    19261 caacataatc attgacatta atagtgatat agaaggttct tgaatagcag ttgtaaagat
    19321 aattttgagc caacagttgc aaggccttca agactttacc atggtagccg ataatacgac
    19381 ctggttcgtt agtatcaatt tgcaaattga tgctacgacg gttataatca tttgaaagtg
    19441 tagcctcaac atccatgtca tcaataatcg tttgaacata agccattact tccgtagcta
    19501 cttgttcaat atcaaagttc gtttcaactt tcaagcccaa gtcttctagt tcttgacttt
    19561 cagcttggtc ttgctcagtt tcaaggtcat cagcgcctgc ttcttccctc atcgcttcct
    19621 cgatttgaag ttcatttaaa atctcaatgt gaccagtttc ttctaagata gtgctggcat
    19681 gtctttcatg ttttaagatt tcagccttga cttcatcaga aataccttga ccttcttcct
    19741 ctattttttt aatagcatca accacatgac caaggtcaac ggtttcttca ctaaccgtct
    19801 tcacaggctc gttcaaatca ttgatttttt tcggaacgcc ttttactacc tgttgatttg
    19861 ctttgacaac agtcgtttca ctaatcgctt caatatccac ttgggctggt tttttaccaa
    19921 atagaccaag aaagcctttt ttctccctag aaatgacttt gatatgagcc ttcattcttg
    19981 gaatatctaa ttctttcaat cctttctgga ttgcttcttc aacagttgaa cctgtaaata
    20041 ctaccattac cagattcctc cttatttatt tcgttttctg agcctttttc ttggcttttc
    20101 tttttctatt ttccaaatct ttttgtgcct gtactacggc ctcgcgctct gcgataatct
    20161 tgaatggatt attcaagaaa taggtttgca agacttgata agcattagac actgtccagt
    20221 atagggcgac tccacctggc gcataaactg caaagataaa aatcaagact ggaatcccat
    20281 acatcatcgc agtcgtagcg ccatttcgct cagacaaagc tttgttggac aaccaagtac
    20341 ttaaaaaggt gaatactgct gctaaaatcg gaagaacaag ggttgtatcc acactaccaa
    20401 ggttaatcca taagaaatga cctgtcttta aaaagtcaac tcttgatagg gcttggaaca
    20461 gggccaaaat aaccggcatc tgaatcaaaa tcggccaaag agagtctgac tgtctgacac
    20521 ccatttcttt aaatacttta cgcatttcct gctctagttt ggttctgctt tccatatctc
    20581 gacctggata ttgttctcga agcgccttaa tgcgtggctg agcttcctgc attttcctag
    20641 aagccaccat ttgcacctga aagactggca agaggactgt acgaatcaag accgtaaaga
    20701 gaataatccc cactccgata ctaatatcaa acgataaaaa gcgaataatt tccgcaaaga
    20761 agtaaaccaa tttactccaa aaatcagccg attcggctgt aatatcgcta gttaccccat
    20821 tagtcgcaca ggctgtcatg attaacagag acagtcctag caaactagtc aactttagtt
    20881 tctttttcac tcccatttcc ttcccggtaa atctttgata attttaatac atggagtaga
    20941 tttttctcca tctctgcgta tcccaaggtt tcgactcctt ttcgagcaat gacaacaaag
    21001 tcgacatctt ctaccagact cccttttgca ttctggataa tatgccgaat ccgtcgctta
    21061 atttgatttc tagtgacggc attccccagt tttttgctaa ctgatagacc tactcgaaaa
    21121 tggtttttct ggttttctaa ttggtagacc acaaatttgc gattagcaaa acttgtcccc
    21181 tccttgaaaa tcgccttaaa atctttctct ctttttacac gaaagttttt cttcaaaact
    21241 caactccatc tattaaatta ctactattat accatatttt tcaaaaaagc caatcatagc
    21301 aaggttttgg acaatttcat cagaaaaaga agctggaaaa ataactttcc caactccttg
    21361 tattgaatat ttttttagtt tcacttattt tttcaagcgt tcaacgtcac gggcaatgac
    21421 taattcttca tctgttggaa taaccaagac acggatttta gctgcctctg ttgagatgtc
    21481 tcctgtaacg ccaaagacat tcttttcatc atcaacatca caaccaaacc acgaaatccc
    21541 tgagattaca tcacgacgga aactctctgc attttcaccg acacctgctg tgaaaacaat
    21601 ggcatctgct ccatttagca ctgcaaggta ctgaccgata tgtttttgga tacggtcaac
    21661 atacatttca taagccaagc tagcctcgtg attcccttct gctacagctg cttctatatc
    21721 gcgcatatcg ctagaattag cagaaactcc caaaagacct gattcacggt taagaacacg
    21781 actgatatct tctggtgtgt taaaatcctc tgtatattgc attaaataag gaatgatagc
    21841 tggatcaata tcccctgtac gcgttcccat cataatacca ccaagaggag tgaaccccat
    21901 agaagtgtct acagatttgc cggctttcac agctgtaatt gagcctccgt taccaatatg
    21961 acaggtaatt aacttcaagt cttctaatgg acgtcccaag agttttgcag cttctcctgc
    22021 tacaaactgg tgacttgtac catgagcacc gtatttacga accttgtttt ctgtgtaata
    22081 ttttgttggt agagggtagc gataagcttt ctctggcata cttgtgtgga aggaagtatc
    22141 aaaaacaact acactggtaa tgtctggcaa caattccttg aaggcacgaa cacctgctgc
    22201 atttgccggg ttgtgtagag gagccaacaa actcaactct tcaacttttt ctaaaacatc
    22261 tccctcaaca actgttgatt ctttgaaata ttctccacca gcaacaacac gatgtccaac
    22321 acctgtaatc tcgtcataag ccttgataat atcgaaacga atcaagtcat ccaataaaat
    22381 tttaacagct tgtgtatgat tttcaatatc caaaatttgt tgttcagaac ggccgtcaaa
    22441 ttttacagtt gaaattgaat ctttcaaacc gatacgttca atcaaacctt tcgccaatac
    22501 tttttcttct ggcattaagt ataattgcca tttcaaactt gaacttcctg cattgattgc
    22561 aattgttttt gtcataacat gatacccctt tttaagcgtt ttcaactatt ataacaaaat
    22621 ctattttata tttcagtacc ttgagtccat ttttgaaaat tttctttaaa tttcattaaa
    22681 acacttgcat cttgcaagct agcaagtgga taaacaaaag gctctactgc tatttcactt
    22741 ttcttctgta ggataaaaat agtcttagat tgtttagcat tagcaaagag attttcaggt
    22801 aaactaatca tagcaaccag acttgcctcc tctttcaacc agactttcaa caaattactt
    22861 tgaggactgg tcaacaaatc actcggagct agaaaaatag cgtatccgtc tgacttgagg
    22921 tacttaagtc cttgttccat gagcaagtga tgggtgtaag tatgttcttg actagaagca
    22981 acttgatggc gcgacgcaac ggcatcatca ggataatagc caacaggcaa gtcgctgatg
    23041 accacatcac tttctttgag catttgtgga cgaacggcat ctccttggac aaagccagcc
    23101 tgcaaaccaa ttacatctgc catgctagct gccaaatcaa tcagcaaatc atccacttcc
    23161 attcccaaat aatccacctt tttagtaagc gaggtcaaga aagtagcgcc caaaattccc
    23221 atcccagaac ccatttcgag gatagtaatt tcctcctctt taaacagctc ttccacaata
    23281 aacaccaaaa gtaaagcaat agcatccggt gtaaactggt gattggcctg caagggttct
    23341 gtttgcccag ccttcatcaa gagaaactgg taggtcttga gccattcttc tttgcgtagt
    23401 gctaaacgct taagggtctg attgttgtct ttgacctgtt ctagctcagt ctcaccatcc
    23461 agatagatgc tgttttgctc caccaaggcg tcataaaagt tggtcgccaa atcactttgg
    23521 atgacttgga cattctctag taaataggta taagcttgtt caattttttc aaaatccata
    23581 ttcctatctt atcaaatttc ccttcttttt tccattctta tagaaaaatc actccctgac
    23641 taggcgagtg atttttgggc tactattaaa aagaattctg agtgatttcc ttgaaacagg
    23701 tcttcagcgc tatagagaat ctgactatgc acagatgaaa aaccatgctc aattagcttg
    23761 ttttccagtt cagctaaatc aaatccatga tgattagctt ctgtcttggt aaaatcagca
    23821 atgatgagtt tcccatcttc cttcaaatgt tgatgaaaca gtgagagagc cgcatccaaa
    23881 tcaggcatat gatgaagaac ccgactaaca gcaaggcaat caaactcttt ctccaaggga
    23941 tttttcggta aatcttgctc caaaaactgg atattcttga ttgcttgctg ctccactttc
    24001 aaacgagctt gctccaacat tttctcagaa atgtctacaa gagtgactga cttagcctgc
    24061 ttggctaggg gttaggggca aggctaatag acccgtgcca ccaccgaaat ctaaaatttc
    24121 tttgtatgat agaagatcaa tctgtttctc ggctgcttga cataccaagt ttgcgaggaa
    24181 gatattttta gggaaatcga aagtttctgc tttgtggtta aaatcatgtt tcatatcttt
    24241 aatttagcac aaagtatagt aaactgaaat aagatataaa caaatgaatt ggagcttaac
    24301 atccatttcc agcaattttc tagaaactac agtggactat tctggattca acgcattata
    24361 gttgaattga ctaggaattc tctttctttt caggcttctc ttctgatttt ttcttctcca
    24421 ctttttcgct tgaatcggtc gctacctctt cctttttatc tcttttctct tctttgattt
    24481 tgactgaagg aaacagaaac tcatattggc tcttatccgt acgaaccctc gtcactaagc
    24541 cagttttctt gttttgatag cttacctgac ctagattaaa aacctgttcc ccactttctt
    24601 gctcaacctt atctttggtt cgtttagcca tagcaaaagc aaccaatttt tctttattca
    24661 aagcatagtc ttgatagtgg gcgacttgtc ggttcaaata aaattgcaac aaaagactaa
    24721 agatggctgc tatggtgact gcgtagagga gaacacctgc cttaactttt ttctttttcc
    24781 acacgataga tgaactccct ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt
    24841 tgattgtcct ctgtaatctg agctgatttg aggccataaa ccataggctg ataacctcga
    24901 ccacgagcat tcgttttacg aaaatcgtct gactttgact taccgatggc gatgtccttg
    24961 ccatcttgct tcatgtatag gcgattgcct tctacttttt cgaactgcga acggtctaat
    25021 tctgcctcaa gttggtccac aaacaagagc cactcctttt gctcgctttg ttgctggtag
    25081 cgaacttctg aaatgaggag ctgactcata gtttgaaaaa ggagtaatcc cccactgatg
    25141 acaatgaggg caagtaggga ttctaacaag gtaaaagcct tgaccttatg gctctttgat
    25201 tgccaacaac tgttctgaac catggtagac ctccaatcct ttttcactag aaaatacctg
    25261 aatctcaact ccgttgatgc ttacctgatt ttgccccgtc tgcagggcca tcttagctac
    25321 cctcaagact tcttcctttt gcaagatttt tgcttcctct tgcctatttt tttgaatttg
    25381 tcccaaaagg agggtcgcaa tgctggcaaa gatagctaga gcgactactg cttccagtaa
    25441 aatcactgcc ctaatttttt gtttccttaa tgcgtttaat ttttccattt cctagatata
    25501 attgatagcg aatcgctcct ttactggtct gaaattcaac cttagccagg gacgaattgc
    25561 ccccagctcg gtcaaatgta atactttggc ctgatggtgc ctgaattcct ttaggaactg
    25621 tcaacttttg actgccattg ctaagcgtct gcccatctaa atttagatta gtcttttgct
    25681 gactggctac actgcgtttt tgggtttccc gatagagttc ttcaaactcc ataaagaaaa
    25741 tctgttcctc taccgccgca aaagtggact gaacagagcc ggacaagccc aaggcaagga
    25801 tactcacaag acccaaaacc aagagacttt ccagcatggt aaaggcctta atcattgact
    25861 ttacgatttg ctcccacatt tttatcattg tattctttat aagctttagc ctgttcttcc
    25921 gtgatgcgtc catcttcttt taacttgctt aggctagcat cttcattctt ttccaagcta
    25981 taaagttctg cctggctttc caccacctta acaacagctg cttttccttt gtcattgact
    26041 gcttcttttt gcttggtcag attaggtaca aagagcaaga aaagcacgct gataatcagc
    26101 aagaccacca acatctccac caatgtaaaa gctttaacct tagctttttt caagaatgtc
    26161 atcatttttt tcattttaaa aatttacctc catattttga tacatgggca tgagcattgc
    26221 cgcataaagt aaaacgataa tcagtgccac aaagataaaa accagtggct gcaccaaatt
    26281 catggtgcgg ttgactcggg taaaaaaggc ttcccaagtt ttttcagcat agatttccaa
    26341 ctcactaccc agcttggact taacttcccc atactctatg atgagactca attccttcct
    26401 aaagaaagga taggttccta tcgtctgaga aaattcacgg ccatttttca gggtttgagc
    26461 cagatcttga ccgatttctt taaagagctg ggaaccttgt tcctgcatca tttgaaaaat
    26521 ctgcgtcagc tccattccct gtgaaatcat attcccccat tcacgtgcat aataggctgt
    26581 caagtaggtc tgcacaaaga ttccaataaa gggaaggcgt gctaagatag aaaagacact
    26641 catcttagaa cttcttttat aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc
    26701 taccatgact agaaaaattt gtggcagatt accgataatt cgggtggcaa tattgctact
    26761 atccagttgt gggagcaggt aattccgtag ccccagcata attaagagaa gaaaacccag
    26821 caaaatcaaa ggataggtcg ctacttcaat taactttttc ttgaccttgg ccagattgtc
    26881 tagatattct tctatctttc ccaaactcag gtgaagattg ccatgaactt cagctagaga
    26941 taactgagtg acaatggtac ttgaacatcc caaactttcc atcatttctg agaatgattt
    27001 cccctgagac aagcctgtac gcatctgggt cacacactgc ttgtccaaca aggaactcct
    27061 atctaaaaag gagatagtct ccaccagatg aaaaccgcta gaaaagagat tgttaaatag
    27121 ggtgatgata tttttttgct tagctgtagc taattttttc cgtctcagcc tgaagacttg
    27181 tgatatgtcc atctttaaga agctggtcaa tttgctcatt ccacttggct gcttggtgtt
    27241 cttgataatc tctgtttgca aagtcaacga ttcctcctcc cccgattaat ctctggtagc
    27301 agactccttg cagaacaact gccaattctt cttcactcac acccaactcc agcagacgct
    27361 cataaacacc tcggatactc ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac
    27421 tagctctgac cactgcacgc gccgtctcga tgtcacgaat ttctccgata atcaagagat
    27481 ctggtcgatg acgcaaggaa agtttgatta gattttcata ggttagaccg attgcttcgt
    27541 tcaactgcaa ctgaagcatg tcgtcctgct tgatttcgac aggatcttcg atggacataa
    27601 cttgctgtcc tttaaagagt gacttggaca attcatgcat caaggtcgtc ttaccactcc
    27661 caaccggacc agcaaaaaga tagagtcccc gttgcctgta ctgcttgcct aattcttcaa
    27721 tatcctgaaa ccaaaaatgc aagtcctgct cctcatcgtg caacaaacgg ataaccaaac
    27781 tctcatgccc ccgataatcg cctacagtag ataaacgtag agacgccatc ttctggtcat
    27841 aggcataatc acaggaaccc agttgactac gtcttttttc tcccacattc atacccgcca
    27901 caaacttaaa gtgactgata acggctgcaa acttttcaaa atcatagcta ccaattttac
    27961 agcgctcgtc tcctaccctc atatgaagct cataggcgtc taacttgggg acaaaataaa
    28021 tgtcttgcgc cccttttttc cgagccgagc gaatgatttc ttgtgcaatt tcttgaacca
    28081 tacttacctc ctcacctata ctattcgcaa agcgttagaa aaataaaaaa agcaactcca
    28141 aaaaagttac ttttctctat tttaatttca tacggcaaga acgattcctt tcctgactgg
    28201 tttgtttttc atagcctgag cgtagttttt cgtctgggat aacctgctca tcctgcaaaa
    28261 gagccaaaga atggtattgt tgtaaatact catcacattc atcacaccag cgttggtctt
    28321 ccgggtccca aaaaatggtc atcaagtcgc ttctactttt ataaagaggg gattcttgtt
    28381 ccaatctaaa ccagcaagtt ttgtagtatt tgagagcatc ataatactgg tcaaattttc
    28441 tacttgctac aatatcttct tcccaacctt ctaagaacca ccacggttca aaatctccgt
    28501 acatttctat aacacgatac atattcattc attcctttgt accgtatatt ataaccaatt
    28561 ccgccagaca aggaaagaaa tatgctcatt tcttaatttt ttgataaaaa atccagccat
    28621 ctgatggatg actgaatttc tatttactta tgtacaaaaa tatttttact acttaggctt
    28681 ctgagatatc gttttcgata atgaccttaa tggcatggtg gtctgctgcc ttactgaaga
    28741 cttcgtaggc tttttcaatt tcactgagtt tgaaatagtg agttaccaat ttttctggtt
    28801 caatcttatg actttcaagc gctttcaaca attgtggagt cgtatttgta gataccaaac
    28861 cagttgttac attgatgttg cgaatccaaa gtttatctaa atcgaattca actggtttac
    28921 catgcacacc acagttggca accgttccgt ctacaccgat aatcttttga cagaaatcaa
    28981 atgttgcagg aataccaaca gcttcgatag cgacatccac accacgacca tctgtcaaat
    29041 cataaatttc tttaatggct ttttcagggt ctgaagaatt aaccttatga gtcgcaccga
    29101 atgatagggc agtttccaag cggttatcgt ctaggtctac cataatcaat ttagctggtg
    29161 aatagaattg ggctgttaaa agagcagcca atccaactgg acctgaacca ataatggcta
    29221 cgctgcaacc aggttctact ttccctttta agacaccaat ttcatatcca gtaggcagaa
    29281 tgtctgacag cataaccaaa gcttcatctg acaagtcttc tggagtatgg taaagagtat
    29341 tatctgcatg agggacacgt agatattcag cctgcatacc atcaatcaag tgaccgaaaa
    29401 tccagccccc ttcgtcttca cagtgagcat aaattccttt tttacagtag tagcatttac
    29461 cacaggcaca gacgcaagaa atcaagacct tgtcaccttt tttgaagttg gaaactcctt
    29521 ccccaacttc ttcaacaatc ccaatccctt cgtggccaag aatggtacca ctttggcaag
    29581 taggaacatc ccctttgata atatggaggt ctgttccaca aatagtggtt tttacaatac
    29641 gcacaatagc gtctgttggc ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa
    29701 gtcctggttt aacataagta taggctttca taaagcactc ctccgttttt ttatttgtaa
    29761 tatttatagt tcaattgtaa gcctttttct ttgtttcttc aagctttttt tgtgattttt
    29821 ttaacttttt atttaccagt aaagtaccct gcataaaaaa gcagaagtta gtctctaact
    29881 tctgctttct ctcttatgct tgataacgtt ttacgccatc taggtaggtt gctaccaatt
    29941 ccaaatcttt atctaatacg atgaagtcag cgtcgtagcc ttcacggatt tggccacaga
    30001 cgtcatcgat gtgaacggat ttagctgggt tgaagctggc catcatgact gcttcatgcg
    30061 gattcgcaat tccccattcg accacattct tcaaaccatc tttgagtttg aggatagaac
    30121 ctgccaagtt acctgtcgat ttgaggcgtg cagttccatt tgcaacgaca actgggaatt
    30181 ctcccaacat ataatctccg tcttccaatc ccccagctgt catacagtct gtgataagag
    30241 cgatgttttc tgttcctttt tgtttgataa gaatttcgca agcctttgga tctacgtggt
    30301 gaccatcaca gatcaactct gcataggtat gtggcaattg gtacatggct ccaaccatac
    30361 ccaattcacg gtgagtcaac ccacgcattc cattgtaggc atgcacccaa acactcgctc
    30421 cagcatcgac tgcttttttg gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg
    30481 tcacaccttc gcccgtaact gtacgaacaa agtcttccac cccatcacgt tctggtgcaa
    30541 gggcaatttt attaagcaag ccatttgccg ctttttgcca agaatgaaac tcctcaacac
    30601 ccgggtctct catataagtt ggattttgtg cccccttaaa agtttctgtg aaatatggac
    30661 cttcataata aatcccacga atcttagcac ctgttgcttc tttataatgg tttccaagat
    30721 tttcagtgac tgcaagcaat tgctcataag tggctgttaa agttgtgggt aagaaactgg
    30781 taacaccggt actaagaagt ccttcactca tagtatgcaa tgtaccttca atgttgttgt
    30841 ccatcacatc tacacctgca tatccatgaa tatgagtatc cacaagacct ggggcaatgc
    30901 tataacctgt atagtcaatc acctcagccc cttcaggaat ctgctctaca tgtttcccaa
    30961 acttgccgtc cacaagttcc aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact
    31021 gatccgcttt aatatagtta ggcataatgt taacctcctt aaaagattga ttctacaatt
    31081 tattatgtca attacattat aaacctttct tttttatttg taaatggtat agacctattt
    31141 tttggagata ttttaaaaga gctggatttc tccaactctt ctctttttta atacaagtta
    31201 ttttgattta accggcttgt cttgagctgt ctgcaaagct gtggcaatcg tatctgcata
    31261 caattttgct cctgcttcga tagtgctact ctcactcccg aaatgaacct ggtctgttcc
    31321 tgcccaaatt tctggatgct ctttcgcaac ttgattccaa tctgctatcg taatgtaagg
    31381 tgtcttctct gccaattctc tcatataggc agcagccttc tcaacgatgg cataggtctc
    31441 ttttgtctta tctccctcat aaggagtcac caaaatcata tggtgtccct taggaagatt
    31501 tttcacgata ctgtcccagt catccttgta attctcagga ttatttaccc cagtcgcaat
    31561 gaccaccgtc ttaggtaaaa atttattctg gctattattt agcatgattt catttgcggt
    31621 cttggttgtt acgctgacct gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc
    31681 tgtatttgcc cttaaagcca ctgagtcacc aattaacata gtgccatcag caattcccaa
    31741 actgtttgca tctgcccgtt ctgccatcac cttggtctgg ccaatatttg ttgcagcttg
    31801 cttcaagcca ttgacagtca agtctgtctc aaacgctccc acttgtggtg ccaacaaggt
    31861 caccatgcag acaatgaagg tcaagattcc tgtacctgct gcaagaattg cgtgaatata
    31921 aggcagggga cgaagagttt gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa
    31981 tacatagaat gacagactgg caaagccata agaacaaatc agagtcagta atacagcaag
    32041 aagatttgat gtcaactgtg agaaaatgat atagaaaggc caatggaaaa gataaaccgc
    32101 atagctagta tccgctaaaa agctgataat cttcggctcc tgtatatgat gtgtcttttc
    32161 atgtaagaca cgcgccgcca gaatcatggc aagagctgca agactggcaa gcaagaagcc
    32221 gataagatag gcaaaaagat aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc
    32281 aaagcctcct ccaaaaacta ccaaagtctt tcgtaaatcc cagattttat ccaactgctt
    32341 gacgagggaa gtcgtctgac gaacgcctac aatagttgct aacatacttc ccaaaaagaa
    32401 tggatagaca tgagttaaac tggagaaata aacagaggaa taagaggtca ctagaaaact
    32461 accaataaac atggagaaga aactgatcaa gaaggcagca gcagataaga gaaagaccat
    32521 ccccttcaac tgaccatttg atttagcttg tttggataag aaccaaactg ccaatcccca
    32581 aagaatatag tagtgaacct caactgccaa actccaatta tgaacaaaca aatgaggaat
    32641 gaactgagat tcataactcc cacctgttag gagttcatag aagttggtca taaagcctaa
    32701 gacgcccgca atctggccac caattccagc aacatagtct tggcgaacca agaaagtaaa
    32761 aggcatggtc accaagacca tcaaaaccac aggtggcaca atccgataaa agcgtcttct
    32821 aaaaaatcct atcaaatcaa tctcattgtt cttagaaaat tcttcaatga gtagagctgt
    32881 aatcaggaaa cctgaaaatg tgaaaaagac atctaccccg aaaaatcctc caggaaagat
    32941 cgtctgaaag aagtgataca agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa
    33001 ccatttaatg cgcatacgag tttattcttc ctttcattgt acactttatt ctatcaaaaa
    33061 aaaaagaaaa atcctaagag aaaacttagg attttttata tcaattccat tttagaaatt
    33121 acgtcctgac ttattatagc catatttttc cacaaaatac tcacggaatt ccaagagatt
    33181 gtcatccatg atggcttgtc gcacttgctt catcaggtta agcaagaagt aaagattgtg
    33241 gtagctagtc aagcggatac caaaggtttc atcagccttg agcaggtgac gaaggtaagc
    33301 gcgtgtatag ttattacatg tgtagcagtc acactcagga tccagtggcg taaagtcctc
    33361 agcaaactgg gcatttttca caaccaaacg tccttgactg gtcatacaag tcccgttacg
    33421 agcaattcga gtcggtaaga cacagtcaaa catatccacc ccacgaatga ccccatcgat
    33481 caagctatct ggcgctccca cacccatcag ataacgaggt ttattttcag gtagcagttg
    33541 agttgtaaag tccaagaccg cattcatctc ttcatgggtt tctcccactg ccaaaccacc
    33601 gatagagtag cctgagaaat ccatgctgac aagatcatga gctgattggc ggcgaaggtc
    33661 ttcaaatcct gcaccttgca caattccaaa caaactttgg tcatgtggac gacggtgagc
    33721 cttcaaacca cgctcagccc aacggctggt acgctcgatc gatttcttaa cgtagtcata
    33781 aggttgataa aactgaggac attcatcaaa ggacatcatg atgtctgaac ccagattatt
    33841 ctgaatagag atggcttttt ctggggatag gaacatctta gaaccattta gatgattttt
    33901 aaaggttact ccttcttctg tgatattacg gctatctgct aaagaataaa cctgaaaacc
    33961 accactatct gtcaagatag gctggtccca attcatgaac ttgtggagac caccagcgcg
    34021 tgcaatgagt tcatctccag ggcgaagcca gagatgatag gtgtttgata ggataattcc
    34081 cgaacccatc tccttcaatt cttcaggtga ctgagttttg acagtggctt gtgtcccaac
    34141 tggcataaac ataggtgtcg gaaaggtacc gtggggagtg atgatttctc ccagacgagc
    34201 tcctgtgtgt ttttctttct taatcaaacg atatttgatt ggtgaatctg acatttttta
    34261 cctccgaagc tgggaaagac agtcccagtt catacagtgt gcccaaggac acactgtatg
    34321 attttatcaa aaaaagtagg aactgtcacg aactatgtat aagaactatg gtataataag
    34381 agaatgaact atccaaaaat tgatttaaaa acaattcgtc aggagtcaaa acattttcag
    34441 gctgacaccc cccgtctctt tctcctctat atccttccca gtatgctggt catcttatct
    34501 ggttttctta atcccttatc tcggatccac gggactgttt tagaacagcc atttttcagc
    34561 atacttggcc aaatacttca agcctacctc tttcctctac tagtctcctt tatcgggact
    34621 attcttttga ccagttccgt ctatgcaaca ctgacactca tgaaagattc taaaacggag
    34681 ccatctgtaa aaaacagcct agctctcttt gatgaggagc gcttttctca aacctttttg
    34741 accctacttc tcaaacgttt ctatctcttt ttatggagta tccctaattt acttgggatt
    34801 cacctcctct tttatagtag ctttttagcc aaaaaattcg tcaccctaca tcctgagttt
    34861 ccaagtctag atctctcatc agttgaaacc gagcgtttcc tcatggtctt tggactctac
    34921 tttcttgcaa gtctcatctt gatcattgta ggaaatatcc tctatattcc acagtattat
    34981 gcctattcac aggtggaatt tcttctctgt tatagtctag acctaggaca ggtcccacca
    35041 agacgaatcc taaaaactag ccgttccttt atgaagggct acaagttcca gcactttgtc
    35101 ctagatttac agcttcttcc ttggtacttc ctcaattgga ttacctttgg cattgctagt
    35161 ttttcactcc taccttatat ccaatgcact aaaattatgt tttaccgagc agtattggct
    35221 cgaaaacgtc caaaagcttg aaggtttttc ccctcaagct tttttctatc aatgagtttc
    35281 tccgcctacc aacttgagtt cctgatctcc atgttctatc atagcgccga ttgctgcttc
    35341 tatccctcgc cgaatatcca ctaaactcat agctggagta gtctgtctgt tcaccacctg
    35401 ttccatcata taaggaatat gcataaaacc tgccttaaca tatggaaatt tcttttctac
    35461 caaatagaga gcctgataca tcaaatggct gcagacaaaa gtccctgccg tattggaaac
    35521 agaggccggt aagccctctt tttttatagc ttgaaccatc gctttaatcg gcaaactact
    35581 aaagtaggcc gaagcaccat ctaggcgaat gggacggtca atcggttgat tatcttcgtt
    35641 atcagaagta cgtgcatcgt cttgattaat ggccactcgt tcaggtgtca aactagttct
    35701 tccaccagct tgcccaatac aaaggacaaa gtcaggttga taacgattca tctcttcttc
    35761 caatacttga gcagatttgt gaaaaactgt cggcacctct agccagcgga cctcagcacc
    35821 atggatttca gctggtaaac ctttaatggt ctccaaagtt ggattgccct tttcccctcc
    35881 aaagggctca aaacctgtca ctaatacttt catttctaac tcctcaaaac caattcaatg
    35941 agactttttt cttaaaaaca agtataacat atttccctta ttctggatta aaaaggatta
    36001 gcgagattag aatcgacctt caagtgtatt taaagagtaa aatactaatc aaggccaaaa
    36061 tagctgatcc accttgtttc aaaataattt ttttatccgc tgttaaagag ccgtaagtcg
    36121 cagcaccaat cacaaataag acaaaaatag tcacaatttc taaattctgt gagaaataaa
    36181 tgacatacaa gagaaagact cctagcagag ccttataaat cccttgattt ttgaacaatg
    36241 aacttactga cggatgagcc aattcttcct tttccatatt aaatacacga ctagtcgcat
    36301 ctgattgcgt ggcaatactt tccaaataaa aaatgtaaaa atgctccaaa gcaacgatcg
    36361 ttgttaaaat aattgacatc tatttctcct taaatttcta tattttcaat acccaaaacc
    36421 aatttattta ataaacggct gagttctgtt ctctcaaact ctgttaagat actttccatc
    36481 tcttccttaa ccttgatatg ttgcagaggg ggattcacca ctaactgctc cttggcatac
    36541 ttcgcagcct ctaccaacac ttcccgctga ttttcaggat tacgatgacg ctccaccaaa
    36601 ccttccgttt ccaaaatctt gaaatgccgt gtcaaagcag cctgatcaat tttcaaacgc
    36661 tcctgaaccg ccatttggtt acaaagagaa tgctccagca aaaacagtaa aatctgatac
    36721 cgtgtcaaac taatcccaag cctttttcaa acaattgcgt actcgcttgc tcagacaagc
    36781 ggagttgata cagtaaatct tgaatctcta gcatttcttc ccctctcttt ttattgattt
    36841 atcaatagtt gaccagtcaa ttataatata aagtatagtg aaatgaaata agagcaggac
    36901 aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagcagt tatgtactat
    36961 tctagtttca atctactata aaatagattg caagaatgtt gcttggatta ttacaagata
    37021 ataactttcc attttccatt caaattgata ctcaatgaaa atcaaagagc aaactaggaa
    37081 gctagtcgca ggttgcccaa aggacagctt tgaggtttca gataaaactg acgtggtttg
    37141 aagagatttt cgaagagtat gacaaagaaa aaacgaacga gaatcgcttc ctatcacgaa
    37201 agctagatct cattcgtcaa aatgatgtta ccaagtcggg tttatccatt cattgaaacg
    37261 tgaacgtggt catagtgatt ttctgtcaca ctaccacggt ctggcattgg attccaagtg
    37321 ttagctggcc catatttgct atcgaatgga gcatagaaac gttgtttcca gatgatgtaa
    37381 ctaatgccac ggctggccat gttttgaata gcatattccg caatcttatc ccctaattct
    37441 gaacgttctg gtaccataaa gtcgatagcc aaaccttttc cgtgatctcc actgtctcct
    37501 ggacgataac cactaaagga tgtaatgcca aacaagttag caatttcttc tttaaaggca
    37561 gctgtttgtg gttgaagacc tgcattttca gattttgcta ctgcaagtcc agcataatcg
    37621 ggcgcagctg gagcctcgta agttgttgaa attactttcg tctcttctgg ttgataagta
    37681 gaaactgctg ctgtagctcc atttgatgat gctacttctt ttgcttctga acttgttgta
    37741 gttacttcca ctgctgatgc agcttgaggg cttgcttgtg tttcctgctt ctcagctgga
    37801 gtcgtttcct gaggagttgc ttcttcaact gggcgagttg tttcggtcgt ttgctcctct
    37861 gggacagaag tgcccgtaga tggtgccact tcttcagaag caatcactgt ctttgtaact
    37921 tctgcaattg gttgagaaag gtctgcaacc tgaacagttt gatcatcaac ggtcacttga
    37981 ttagtggtca aatctgctgt cgcagttgtc acttcttcac tagagtctgc ttgaggtgtt
    38041 tggatttcaa cttctgttac ttcttctgct tcattgacag tcgttgtcaa aacagtttct
    38101 gggaaaatca agtccatatt agtgattttg ttcagattcg caagcactgt gacatctaca
    38161 cccaaggctt ctgcaatggt gctcaaagta tcaccatact gtacggtata acttgttttg
    38221 ttgtccgttt tagtcaaatc gttttggatt tgctcaacac tacgtgcagt ccaaagaact
    38281 tcttctgctt gagttgccaa tactggggca aatgacaagg ctactgttga cgctaataac
    38341 attcttttct tcattctttc aaattccttt caaatgagta cctgtctatc ataacacaaa
    38401 aaatgtagaa aaaaagccct ctcgggccta tttaacagaa ctgtctattc cttgtaacaa
    38461 actaggttac ttgaaatagt ttgttaggtc tctgtcacaa aactgacaca atctttttat
    38521 cacttagtct caaaaatacg ggaaatatct gctaacgctt gaatcctgtg attcccttca
    38581 taagtagact ctaaaaagtt gatgctttga atcccactat tctgggcaaa ttccacatcc
    38641 agagtccgat cccctatata ataagtatta tcagaattca actgatactt atctagcaga
    38701 taggtagccg cttctggact tggcttccgc acaaagccac tctgactggt taaaatctct
    38761 gtaaaatagg attccacccc caagtccttg agaatggtaa aagcgttgtt ccccttatga
    38821 gtatatataa actgctgaat tcctgattcg tctgcccaag ctagcacctc acgcgcacct
    38881 ggcatcaaaa ctacctgagc attcttctca gccagactct gggcacgcac ctgatttagc
    38941 acctcaacat ccagatttct atcttctgcc acccgcacaa gcaaatcttg caccgaatac
    39001 ttgaagataa actctctcac cttctcctta tcataaggaa tagaaaactg agcaaaagtc
    39061 tcctcaatcc ctgataaaat cgcttcgtaa gagtccaata aagtcccgtc taaatcccaa
    39121 ataaaagctg ttttttgcat ttcctatcct ttcaagctca tatagcgctg gtaacgatag
    39181 cgtagaaata accagcgaaa accattatcc aagagagacc ctgcccaaat accaggcaag
    39241 ccccaaccaa gcacaatccc cagcagatat cctgttccaa tgcggataca ccacatgcct
    39301 atacttgtcg cataaaaagg gaggcgtgca tttcctaatc cctgccagac tgccgtatag
    39361 atgactgttc ctgtcgtcat aggggttcca agtagtgaaa acagtgtcac tagaacacta
    39421 gcctccaccg ctagagaatc agtcgtatag agatgagtta atggtacacc caagacatat
    39481 atactaaagg acaggggcaa catgaggaac agagaaagcc aaaaggtttg tttactcaaa
    39541 ctagcgactc ttttccaatc atcctctcca actgctcggg ccaacagcat gaccgttgcc
    39601 gtagcgacgc caaagacagg catatagtta aactgggtca agacttctcc gattgcattc
    39661 ccagcaactg cctccgtccc aaaagaaacg accaaggcaa tgatcactac atctccagcc
    39721 ctcatcataa gtcgctctcc agctgctggt aaagccaagg tcaacagttc cttatctaaa
    39781 ccaaaagttg gcttcccata aggcagtttt aattgtgacc acaaaatcac aagaccaacc
    39841 aaacgagaca gaattgtccc ccaagcaaca ccagctatcc ccatatccag aacaaaaata
    39901 gctagacttg aaaaaagaat attcaaggca ttggataaaa aactaacata gagaggcaga
    39961 cgtggattat gcgttgcacg aatcaaggct cccaaactag tcattaaacc taagagaaca
    40021 atcgatccgc ctaccaaaga tagatacagt ccaccactct cagctacagc cctctccgtc
    40081 cccaaaagtc ctatcatctc tttcccagcg aagatggaca aaaatcctaa aaggaaactt
    40141 aatagtaagg taatcttcaa cgcctcagtc acatgatagg ccaacttcga ctggtctttc
    40201 tgtcctatgc tttttgaaat aacactggaa ataacagctc ccagagcgat gaaaatcgcc
    40261 tgataaatgg tgataatatt accagctact gaaacccctg aaatagctat caatcctaaa
    40321 tgagcaacca aataactgtc caccattccc attagcatct gcaaaaagtt ttcacccata
    40381 gctggcaatg caatattaag aatgtcttta tttttcttaa acaatctctc ctcctgatga
    40441 aaagaaactc agttggtttc ccaaccgagt ttactccctc tatcttaaag tcctaaataa
    40501 gcctcaaccg ctacttgcat gtcagcagct gccactgttg tcttgtgacg aacaggagct
    40561 gtctcaagcc catcaactgc tggtggcact gcaacgcctg agatttcatg taattgagcc
    40621 aaagcttcaa agtctgttaa acctgctttt ccagttacag cttctactgc aactactggg
    40681 aacttgtagg gactagctgt tgaagcaatc actgtcttag tcacatcatc agtaaccgct
    40741 tggtattttc tataaactgc tgaggcaacc gccgtatgtg gatcctcaat ataagaatct
    40801 aactcataaa cacgcttgat ttctgccgct gtttcttcct cagtcgcata ttcagctgca
    40861 aagaggtcca aaatctctgc atcaaagtct gtcaacttat attgtccttg catgttcaaa
    40921 gcattcatga gttcagctgt cttttcagca ttatttccca aaagatggaa aatcaagcgc
    40981 tccaagtttg aagataccaa gatatccata gatgggctgg ttgttacctt aaactcacgt
    41041 ttcttgtcgt aaacacgtgt cttgaagaag tctgtcaaaa cattgttgtc atttgaagca
    41101 cagatcaatt taccaactgg gagaccgatt tgtttggcat aaaaggcagc caagatattt
    41161 ccaaagtttc ctgttggtac tgtgaagtta atcttatcac cagccacgat ctcaccagtc
    41221 ttgaccaact gagcataggc ataaacataa taaacaatct gtggcaccag acgaccaatg
    41281 ttcatagagt tagctgatga aaattgcaac ttgttggtag tcaatttttc acgaagagcc
    41341 acgtcgttaa acatgtgctt cacatttgtt tgcgcatcgt caaagttacc atcaatagca
    41401 ataacatgag tattgtcgcc agtttgagtg gtcatttgta actcttgaat cttgctgaca
    41461 ccatcctttg gataaaagac gataatctca gtaccaggca catccgcaaa ccccgccata
    41521 gcagctttcc ccgtgtcacc agatgtcgct gtcaagataa caatcttgtt ctccaaacca
    41581 tgtttcttag cagcagtcgt cataaagtat ggcaaaatag acaaggccat atccttaaag
    41641 gcaatcgttg aaccatggaa aagttccaaa ttgtattgcc catctaattt cactaatggt
    41701 gcaatagctg gagtatcaaa tttgctatcg taggcattgt tgatacagta gtccaactcc
    41761 tcaactgtaa agtcatctaa aaatgctgac aaaactagct tagcaacttc ctggtaagaa
    41821 gcatctttca atttgtcaaa gttcaaatct acctttggat aagtaaccgg tgtaaacaaa
    41881 ccgccgtccg tcgccaaacc ttgcaaaatt gcttggctgg cagttactgt attgttggca
    41941 tcacgcgttg attgataaac taatgtcatt actctctatc ctttatctat agtctcgtcc
    42001 attatatcat gatttttcag aaaattctcc ctttataaga gaaattatag gctcaattct
    42061 tctctcaaag gctgtaaata ggtcatttct tccttatttc tcaccactag tccctcctca
    42121 gctagtagga gtaagtcttt ggaaaattca ataatcgtag tttcttcctc atctgtaaga
    42181 tttttcttag aaaattgtct ccttaaagac ttgtaatcat aaccaaatac tttaaagaaa
    42241 ggtgctgttt ctaagtaagc ttctaacttg tctaaattaa ccaataatcc caagtgaaaa
    42301 gctgcagaag caaaagtcct atcaagtggc tgtgtacaca cactacgaaa ctcaactgtt
    42361 cctcgagtcg ttaagtcttg gtactggtaa ctacgatgag tttcaaaatc cttctcttgg
    42421 gggtaaataa taacctcatc cccattcaga gaaaatgctt ggatttcagg cgtagccaaa
    42481 tagtccccag cctgaatagg ataaaaataa taggtctgcc catcacgttc cgcagtaaaa
    42541 atcgcagaat gatttagata gtcaaaaaaa tcagcttcat cattaaggag tctagcattg
    42601 accccaacat tctctggata gataccatgc atagattctt cccagaaaat atcccttgaa
    42661 attttcgtat cccaatccgc acccgaaaac tcagagtttg caaataaata agccttagcc
    42721 gcttcaattt gagtaaaagc attaatcacc cgtaagtagt tggtttttga aatatccagc
    42781 tgaacctggc tcccacagat aaaagtacca tattcaggga aatgatgtaa atctgattta
    42841 ataatatttc tactcaaatt caaataatcc atcaacatct gatagcgtgg ataagccact
    42901 ggacaattct catttttatc ccagttggga tggataccac agccaacaat agcatgattt
    42961 gattcagcta actttctctg aattacattc atataattat tgaaacgatt ttcgacctct
    43021 tgaatcgttt cagccttacc aaatgcaaac tcaatcgttg tataggaaac ttcaaataaa
    43081 atagcatcct gacttatcgg atctactaac tggatcagat tgccaaaatc atctaccttt
    43141 gctacggtga gatccaaagt agaaactaaa taatgaaata gatcctttat aacttcaaca
    43201 tctgtagcat ccccttctaa acttgcaaca ggatactcca actcaattcc gacaaacaat
    43261 tcaggatttt ctttaatatt tttcaaatac cgatgtttta ataaatcgat agaacaagac
    43321 atactaccct acactttctt aatctaaata aaatttgaat aactataatt ataccaaaaa
    43381 taatataaaa aaagaacgaa gaataacaac gttcctaaca ctatactata ccggcggccg
    43441 gggtcgaacc ggcacgtcct tgcggacact ggattttgag
//
LOCUS       DAVHSH010000012        37290 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000012 DAVHSH010000000
VERSION     DAVHSH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.012"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            194..1957
                     /gene="aspS"
                     /locus_tag="VVR08_000767"
     CDS             194..1957
                     /gene="aspS"
                     /locus_tag="VVR08_000767"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU6074718.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1935..2876
                     /locus_tag="VVR08_000768"
     CDS             1935..2876
                     /locus_tag="VVR08_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6074719.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2996..3076)
                     /locus_tag="VVR08_000769"
                     /pseudo
     CDS             complement(2996..3076)
                     /locus_tag="VVR08_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3212..4198)
                     /locus_tag="VVR08_000770"
     CDS             complement(3212..4198)
                     /locus_tag="VVR08_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6074720.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4208..5008)
                     /locus_tag="VVR08_000771"
     CDS             complement(4208..5008)
                     /locus_tag="VVR08_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU6074721.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5261..6103)
                     /locus_tag="VVR08_000772"
     CDS             complement(5261..6103)
                     /locus_tag="VVR08_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6074722.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHSWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6105..7397)
                     /locus_tag="VVR08_000773"
     CDS             complement(6105..7397)
                     /locus_tag="VVR08_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6074723.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSSFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7508..8779)
                     /locus_tag="VVR08_000774"
     CDS             complement(7508..8779)
                     /locus_tag="VVR08_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6074724.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9329..10846
                     /gene="malQ"
                     /locus_tag="VVR08_000775"
     CDS             9329..10846
                     /gene="malQ"
                     /locus_tag="VVR08_000775"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU6074725.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10872..13130
                     /locus_tag="VVR08_000776"
     CDS             10872..13130
                     /locus_tag="VVR08_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEU6074726.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSNEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14176..14748)
                     /locus_tag="VVR08_000777"
     CDS             complement(14176..14748)
                     /locus_tag="VVR08_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074727.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            complement(15370..16218)
                     /locus_tag="VVR08_000778"
     CDS             complement(15370..16218)
                     /locus_tag="VVR08_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6074728.1"
                     /translation="MNTNLKPKLQRFASATSFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16363..16641
                     /locus_tag="VVR08_000779"
     CDS             16363..16641
                     /locus_tag="VVR08_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074729.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16643..18706
                     /locus_tag="VVR08_000780"
     CDS             16643..18706
                     /locus_tag="VVR08_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6074730.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18784..20040)
                     /locus_tag="VVR08_000781"
     CDS             complement(18784..20040)
                     /locus_tag="VVR08_000781"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU6074731.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20182..22647
                     /locus_tag="VVR08_000782"
     CDS             20182..22647
                     /locus_tag="VVR08_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6074732.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGLVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22712..23623
                     /locus_tag="VVR08_000783"
     CDS             22712..23623
                     /locus_tag="VVR08_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6074733.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23853..24551
                     /gene="dapD"
                     /locus_tag="VVR08_000784"
     CDS             23853..24551
                     /gene="dapD"
                     /locus_tag="VVR08_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU6074734.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATSVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24619..25749
                     /locus_tag="VVR08_000785"
     CDS             24619..25749
                     /locus_tag="VVR08_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU6074735.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKTRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALACELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25761..26300
                     /locus_tag="VVR08_000786"
     CDS             25761..26300
                     /locus_tag="VVR08_000786"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU6074736.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFPHEFQTQELIEQALKDGKRVLTPKIYPKGRMDFVVYDPQQLVKTAFALLESQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26284..26961
                     /locus_tag="VVR08_000787"
     CDS             26284..26961
                     /locus_tag="VVR08_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU6074737.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEELFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTIQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27028..27927)
                     /gene="galU"
                     /locus_tag="VVR08_000788"
     CDS             complement(27028..27927)
                     /gene="galU"
                     /locus_tag="VVR08_000788"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU6074738.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27949..28965)
                     /locus_tag="VVR08_000789"
     CDS             complement(27949..28965)
                     /locus_tag="VVR08_000789"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6074739.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29177..29616
                     /locus_tag="VVR08_000790"
                     /pseudo
     CDS             29177..29616
                     /locus_tag="VVR08_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(29731..30156)
                     /locus_tag="VVR08_000791"
     CDS             complement(29731..30156)
                     /locus_tag="VVR08_000791"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6074740.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(30224..30874)
                     /gene="phoU"
                     /locus_tag="VVR08_000792"
     CDS             complement(30224..30874)
                     /gene="phoU"
                     /locus_tag="VVR08_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6074741.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30889..31641)
                     /gene="pstB"
                     /locus_tag="VVR08_000793"
     CDS             complement(30889..31641)
                     /gene="pstB"
                     /locus_tag="VVR08_000793"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6074742.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31643..32458)
                     /gene="pstA"
                     /locus_tag="VVR08_000794"
     CDS             complement(31643..32458)
                     /gene="pstA"
                     /locus_tag="VVR08_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6074743.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32451..33314)
                     /gene="pstC"
                     /locus_tag="VVR08_000795"
     CDS             complement(32451..33314)
                     /gene="pstC"
                     /locus_tag="VVR08_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6074744.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMNVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33432..34307)
                     /locus_tag="VVR08_000796"
     CDS             complement(33432..34307)
                     /locus_tag="VVR08_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU6074745.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34474..35805)
                     /locus_tag="VVR08_000797"
     CDS             complement(34474..35805)
                     /locus_tag="VVR08_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU6074746.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35806..36513)
                     /locus_tag="VVR08_000798"
     CDS             complement(35806..36513)
                     /locus_tag="VVR08_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074747.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36597..36899)
                     /locus_tag="VVR08_000799"
     CDS             complement(36597..36899)
                     /locus_tag="VVR08_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6074748.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(36886..37107)
                     /locus_tag="VVR08_000800"
     CDS             complement(36886..37107)
                     /locus_tag="VVR08_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6074749.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            37069..37290
                     /locus_tag="VVR08_000801"
                     /pseudo
     CDS             37069..37290
                     /locus_tag="VVR08_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10938 a         7078 c         8041 g        11233 t
ORIGIN      
        1 actgacgaag tcagtaacca tacctacggt aaggcgacgc tgacgtggtt tgaagagatt
       61 ttcgaagagc attagcgcta atttttaggg ctttcacctg acttttaaag actggcaaac
      121 ttttctgatg attttcatga agagcctgcg cttttatggt aaaatagtaa cagaataaaa
      181 gaggagagaa ataatgaaac gtagtatgta tgctggtcgt gttcgtgagg aacacatcgg
      241 acaagaaata accttgaaag gatgggttgg ccgtcgtcgt gaccttggtg gtttgatctt
      301 tatcgatctt cgtgaccgtg aaggaatcat gcagttggtt atcaaccctg aaaaagtatc
      361 tgcagaggtt atggcaacag ctgaaagcct tcgtagcgaa tttgttattg aggtgactgg
      421 tcaggtcgct gcgcgtgagc aagccaatga taagttgcca actggtgcgg ttgagttaaa
      481 cgtgacagct cttattgtgc ttaacacagc taagacaaca ccatttgaga ttaaggatgg
      541 cattgaggca aatgacgata cacgtttgcg ttaccgttac cttgaccttc gtcgtccaga
      601 aatgttggaa aatcttaaac ttcgtgccaa ggtgacccac tctatccgca actacttgga
      661 tgagttggag tttatcgacg tggagacacc attcctttct aagtcaacgc ctgaaggggc
      721 gcgtgattat ttagtgccgt ctcgtgttaa taaggggcat ttttacgctc ttcctcaaag
      781 tccacaaatc acgaaacagc tcttgatgaa tgctggtttt gaccgttact accaaatcgt
      841 taaatgtttc cgtgacgagg acttgcgtgg agaccgccag cctgaattta ctcaggtcga
      901 cttggaaacg tccttcctta ctgagcaaga aatccaagat attacagaag gcttgatcgc
      961 gcgcgtgatg aaggaaacaa aaggcatcga agtaacgcta ccgttccctc gtatgaaata
     1021 cgatgatgct atggctcttt acggttctga caagccagat actcgttttg acatgttgct
     1081 tcaggacttg acagaagtgg tcaaaggtgt agactttaaa gtcttttcag aagcacttgc
     1141 tgtaaaagcg attgtggtca aaggagctgc ggacaactat tcacgtaaag acatcgacaa
     1201 gatgacggaa gtagccaaac agtatggtgc caaaggtctt gcttgggtca aggtggttga
     1261 tggagaatta aacggaccag ttgccaagtt cttgactggt atccaagaag aattgacaac
     1321 agcgcttgct cttgaagata aggacttggt tctctttgtg gcggatacgc ttgaagtggc
     1381 taatgcaaca ctgggtgccc ttcgtggacg tattgctaaa gagcttggct tgattgataa
     1441 tgataagttc aacttccttt gggtggttga ctggccgatg tttgaatggt ctgaagaaga
     1501 aggccgctac atgagcgccc accatccatt cacacttcca caggaagaga ctgctcacga
     1561 attagaaggt gatttggcta aggttcgtgc cattgcttac gatatcgtct tgaacggtta
     1621 tgagcttggt ggtggtagcc ttcgtatcaa ccaaaaagac cttcaagaac gcatgttcaa
     1681 ggctcttggt ttctcagctg aagaagccaa tgaccagttt ggtttccttc ttgaagccat
     1741 ggactatggt ttcccaccac acggtggttt ggctatcggg cttgaccgtt ttgtcatgtt
     1801 gcttgctgga gaagaaaata tccgtgaagt cattgccttt cctaagaaca acaaggcaac
     1861 tgatccaatg acacaagctc catcaacagt cgctctcaaa caactagagg aactcagctt
     1921 acaagtagaa gaagatgaaa caaacaaaac gaattaagcg gtggcgctat tatctgcgcc
     1981 gctttgctta tcagataaaa attttacgtg tcttacaaag tatctctcga gaaaagtatg
     2041 atgagaagat ttcggcctct ctggtctatg gttttttatc agcagtagca gttaatttct
     2101 ttttccaacc agggcatgtg tattcgagtg gtgcaacagg tctggcacag attatctctg
     2161 ctttgagtaa tcactggttt ggttttcata ttccgatttc gctaagcttc tacgccatta
     2221 acttcccttt gatggtctta gcttggtatc agattggcca taagttcacc gtctttacct
     2281 ttatcacggt atctatgagt tccttcttta tccagtttgt ccctgtggca accttgacgg
     2341 aggatcccat tatcaattcc ctttttgggg gtgttgttat gggtttgggg attggttttg
     2401 ctcttcgaaa caatatctcc agtggtggga cggatatcgt cagcctgact attcgcaaga
     2461 aaacgggtaa gaatgtcggt agtatttctt tcttggtaaa tggaactatc atgctgatag
     2521 caggtttgac ctttggttgg aaatacgctc tttattctat gattaccatc tttgtctcta
     2581 gccgtgtgac agacgcagtc tttactaagc aaaagcgtat gcaggccatg attgtgacaa
     2641 atcatccaga gaaggtaatt gaaaaaatcc ataaaaaatt gcaccgcgga gcaaccatga
     2701 tccacgatgc agaaggaacc tataatcacg agagaaaggc agttttaatc actgtcatta
     2761 cacgtgcaga gtttaatgaa tttaaacaga ttatgacaca agtggatcca agctcctttg
     2821 tctctgtctc ggaaaatgtt catattctag gaagatttgt tgagatagat aattagtgat
     2881 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta ggtatgttac
     2941 tgacttcgtc agttctatct gcaacctcaa aaccatgttt tgagctgact tcgtcagttc
     3001 tatccacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta gtttgcactt
     3061 tgatttttat tgagtataaa aagatcttgg gtaacaactc aatttcagaa gaaaaggaag
     3121 taaatcttcc cacaataaaa cgcatagtat caagtttttt caatacctga tagtatgcgt
     3181 ttttgctttt aacgactttt tgcccagtct cttatttttc gataattttg tgggcgatca
     3241 attgacggta acaaatttgt ttattgtttt tattatcatt aataatctgg agaatagttt
     3301 caagggaaac acgaccaagc tctaaactat tgatatcgac ataggctgcc aagttgagct
     3361 tgggattaac cgagtcaaag ctgagaacag ggacatccag ctggtgtttg gcaatatagt
     3421 tacaaacacc ttcagctagg aggctatcgg ttgtgatgat agcatcaatt tgtggatcgt
     3481 gcttgaataa tcgcttgcta aatttatagc ccttttcttc cagaaactcg tcggcaaagt
     3541 agatgcgatt gttgtcagtg gtaagtttgt aatgtttaag cgcctgttca tagcctgtta
     3601 aacggtcttt ggtcacgaag agctttttac ttcctccgat aaaggcaatg cgtttgcagc
     3661 cttttttgat gaaatattca gtcgcatcaa aaccagcttg aacattgtcg ttgtcgacaa
     3721 gtgggatgaa aggagataga gatttaccta ggataaggaa ggggaactgt tcttctgcga
     3781 cgagttttac gagagggtct tcttcttggg catagagaaa gattagccca tctacacgct
     3841 tgccgtagac catttgtgaa atagcgttga gacgctcctt ctcatctttc cctgttgcta
     3901 tctgaatggc atagtggttt tcagatgcga cttgagagat gccacgtaga accgatggaa
     3961 agaaaggatt ctggtagaag gcgtctgagt catcaggaag aactaatccg ataacctgag
     4021 tatagctgct taccaagcta cgagcgttga ggtttgggtg gtagttgagt tccttcatag
     4081 ctttgcgaac gcgttttttt gtttcgtcgc taatggttga tttattttga ataacacggg
     4141 ttacggttga aggcgaaaca ccagcagcct tggccacgtc tttaatcgta acgggcataa
     4201 aaatctccta tttatggtaa tttggatcac ggaaatgtgt tttataaaag atagtgacca
     4261 gatacagaac aaaaagaata ttttgtacag taatcagggt tgtcatattt tggccaaata
     4321 atcccaaaat aagtgtaatc agagtcggca atcctaaaca gttcaagata aagtgatagc
     4381 actctttaaa ggttctaaat gaaaagaggc gtgatttctt agtgatataa aggagaagac
     4441 tagctcctag agagacgata aagaaattca aaccaaagag gaagctcgca ccgagaacta
     4501 ggaagaggct gatatagaca cgattttgtt ggtaccagtc tttagaaatt gcttgggtca
     4561 agctgtcttt gcttttgaaa ctctcagtct gaatggctcg gtaagagatg cgggtcagtt
     4621 ccttgctttc cttgctgatg actagttcat ttgtatcgaa atgcagttgc aagtccttag
     4681 gtaattcctt gatttgactt ggaccaatca caacagaagg ggcttgacta gctgttccag
     4741 tataagttaa tgtgccatcg acaattgtag catgttcaga gagatcctgg acaaccttat
     4801 ctgtcagagg ttcatagaca ttatcgataa aagtttctag cggataggtc tcctgggagc
     4861 tgttttggat agcaatgggt accatagaca agctgataag gaagatactg gtaaagagaa
     4921 gttgaaacca gttgagctcg aaacgtttgg acaggggctt acgaaacccc caaatacttg
     4981 aaaaatagga aaatggatat ggaagcatag gtatctttct aaaaggtgtt ttctatatga
     5041 gtattattat atagagaaat gcgctttatt tcaagtctag gagaaaaatt gcttgctaca
     5101 aggatattat ttacagtgac aattgctaat aatcaatgaa aatcaaagtg caaactagcc
     5161 acaggttgct caaagcacaa ctttgaggtt ggagataaag ctgacgtggt ttgaagagat
     5221 tttcgaagag tataaaatga aaaagggtgg cggggataaa ttatcccttg tcgccaccac
     5281 ttgtaagtcc tgaaacaaag ttcttttgta gaaagaagaa gagaatacag attggaaggg
     5341 cgatgaggat agcacctgct gagaagtagg caatcttcaa gtttttcgca ttgttaacga
     5401 aggtttggag acctacggca acagtaaagt attctttctc acgaagcaag aaactagaga
     5461 ggatgtagtc cccgaaaggt cccatgaagg cccagagagc ttgtacggca accattgggc
     5521 gaacaagtgg aagaacaatt tgccagaagc ggcggaagtg tcctgcaccg tctagttttg
     5581 cagattcgtc taaagacatt ggcactgtat cgaagtagcc tttcatgagc caagcattca
     5641 tcgggatacc accaccaacg tagaggaaga tgaggaacca gctgtggtta agggcgttca
     5701 acataagcgc cataacgaag aaggctgtca aagcggccat agttggcacc atttggatga
     5761 tcaagaagaa gaccaaactt tgtttacgag ccaagaagtt gtaacggctg taagcataac
     5821 cagcaagtac gatgatactt gtttgaacag ccatggtaat taaggcgata atcaaagtgt
     5881 tgaggtacca agtaccgtac aaggtttcag tgaagaggcc tttaaagtta tcaaaattga
     5941 ggtcgatatt agtatctagt ttaaaggctg agacgttacc tgctttaaag gctgacataa
     6001 tggtaatcaa cagtggatag ataattacaa ttgatagacc aatcaggtaa aggtaagtaa
     6061 ggctttgagt cagtctacgt ttgagtttaa ttgagttatt catcttagac gtcctccata
     6121 tcaaatgcgt gtagtttctt gaatgcgatc atagagattg agatgacaat gatagagata
     6181 atcaaggtaa cagctgccgc cattgagtat tgaggagatg tacctgttgt caaacggtag
     6241 atccatgaga tcaagatatc ggttgaacca gctccacctc cgacactacc aggtcctcca
     6301 ccattgaaga ggtacatgat agagaagttg ttaaagttga aggtgtattg gctaatcaaa
     6361 gtaggtgccg caacagccaa aatcattggg aaagtgatgt tgcggaattt ttgccaagcg
     6421 ttggcaccgt caatataagc tgcttcgtaa aggtcgttag gaatagattg caagataccc
     6481 aaggtcagaa cgtagatgta tgggaatccg agccaacctt gcatcataat caaggcaatc
     6541 ttagtccaag ttgggtctgt tttccaagga ataagagctc catcaaggaa aggaaggaat
     6601 ttagccaaga ttggcaatac ttgagtgttg atagcaccga cactatcgtt aaacatgttt
     6661 gagaatgtca agatagtgat gaaggctggg acagcccaag gaagaaggaa aataacacca
     6721 aagatacgtt ttcctttgat aaatggttgg ttggcaatga tagctgtgaa gataccaatt
     6781 acgatttgta aagtagaagc tgccaaagcc caaatgatag tccaagaaag aacagaacca
     6841 aaggcagaac ggaaggaact caagctccaa atgtttgtaa agttggtcaa accaacccag
     6901 tccaacaact tgtttggtgg caagtgttgg aagtcatagt tggtaaaggc gatcatcaag
     6961 gttacgataa ctgggaagat aatcgcgaag gtcatggcaa cataagatgg aatgatcaag
     7021 aggtaaggga agccattttc ataaatccct ttgatcatgt ctttgagtgt gcgtggaact
     7081 ggaattccat tgttaatgcg ttttgcaatc gtatgtgcat ctttgatatt tgagaaataa
     7141 aagagtacat aaacgattac aaagattaga tggaaggcac cacgaatcag cataaagagg
     7201 gaattatcac gacctggttt gtcaccaaga gtgatgaggt tgctcaattc aggggttgca
     7261 agtgctagga agtaaaggac aaatacgatg gttacaccaa ggaagataaa acctttggct
     7321 ttttgtttat tgtaaatctg tcctaaccca ggaatgatag acagcagggc tgctttacta
     7381 ggttgttgct tttccatatt aactcctttc ataggatact acttttttat aagaaagcta
     7441 aattatttgt gtctctattg ataaattcaa agggggattt gatttccacc ccccttgaac
     7501 aaatttttta ttcaccaaat ttttgtttga ttgtttcttt gatcaatgtt acagcatcgt
     7561 tagcagctgt tttagcatct ttttgaccac ttacagcatc aaagagcata tttttcgctg
     7621 gatcccaaac tgcagacatt tgagagatgt ttggcagtgg ttgagtgttc ttgaactgtt
     7681 tgataacagc tgttgtcaac tcatcgtttt taccttcagc gtatgaacga gcctcagtat
     7741 tagctgggat ttcgttagtc ttatcatata atactttttg ttgttcagtt gcaacaagga
     7801 agtctacaaa tttttgagaa gcttcaaggt tcttaacggc ttgaggaatg acccaagctt
     7861 taccaccacc gaatgcagca tattcttttc catttggaag agttgggata gttgcaactc
     7921 cgtagtttac tttagcatct ttaaaggctt gagctttcca aggtccgtcg atgatagcag
     7981 ctgttttacc ttcttggaat tgagtttgga ttaagtttcc agcaccttct gtatcttgca
     8041 tacctttagg ccatttttcg taccaagatt tagcgtagtt gatacctgcg atagaaccgt
     8101 cgtttgcaag accgatgtct ttagcgtctt taccgttttg gccaaagacg taagcaccgt
     8161 taccggcaag aagtccatat gtatagtaga agtttgtcca gtcagctagg aaggcagtag
     8221 ttttaccatc ttcaccagcg aatgcgtatt tgctatcttt agcaaggttt tccaagtcag
     8281 caaatgtttt tggagcatct ttcaccaagt ctttgttgta gtacataaca agtgactcga
     8341 taacggcagg agcaccgtaa actttaccat tagcagctgt tacaagagat ttagttgtgt
     8401 cgtctgtttt agcaccatcg ctcaatttca cttctgaaag ttgtccgtca gaaccaaggc
     8461 tacctacacg gtcgtatgga gccatcataa catcagggac attaccagat tggttgtcaa
     8521 gagaaagttt atcaagacct cctagagcat caccagtttt aagagtgact tttactccag
     8581 cttctttttc ataagcttta gcaacctctt caatatagct cttatatccc tcgtctacat
     8641 atacagtgag ttctttgact tcagatgaac cagaatcagc aggcttatca gcagttttgc
     8701 ttccgcaagc taccaaaagc aagctagcaa gtgtagcagt tccaagcacc gcagtgctct
     8761 tcataaattt agatgacata gtgtattcct cccaaagaat agcaagtttt attgataagg
     8821 aaacgcaaac gttttccttt atgagcttag tatagcacaa atagaaaacg gttgcaagta
     8881 ttttttgtaa aaattttaaa aaatttttaa gcttgatttg atagcataat tttgcatttt
     8941 aatagaagaa aagtatgaaa tagataagaa tacagtattt ttaataaaaa tatatggaat
     9001 ctgtctaaag agggaaatca ggaggggcta cctccctgtt tctaatccct atctattttc
     9061 tatagacgtt tgtgctttgt tgcatataaa ttcaagctcc ctaaggaggt tttgtacttt
     9121 gtagactgtc tcgtgagagt caaactttag gattagatag ttttaagtta tctttgctaa
     9181 aatgagttag tctccttaaa aataatcaaa aaagtttttt aaaaacgctt gcaattatgc
     9241 ttgaaaagga gtatacttat aagtaacgca aacgtttgcg cctgcaaaat acgcaacgtt
     9301 ccattatttt aacacacgag gtgctattat gaaaaaacgt caaagtggtg tgttgatgca
     9361 catctcttct cttccaggag cttacggaat cggatcattt ggtcaaagtg cttacgactt
     9421 cgttgatttc ttggtccgta caaaacaacg ttactggcaa atccttccat taggagcaac
     9481 tagttacggg gattctcctt accaatcttt ctcagccttc gcaggaaaca ctcattttat
     9541 cgatttagat atcttggtgg agcaaggttt gttggaagca agtgaccttg aaggagttga
     9601 ctttggtagc gatgcgtctg aagttgacta tgctaaaatc tactatgcac gtcgtcctct
     9661 tttagaaaaa gcggtgaaac gtttctttga agtcggagat gttaaagatt ttgagaaatt
     9721 tgctcaagac aaccaatcat ggcttgagct ctttgctgag tatatggcta tcaaagagca
     9781 ttttgacaat cttgcttgga ctgaatggcc agatgcagat gctcgtgctc gtaaagcttc
     9841 agcacttgaa agctatcgtg agcaattggc agacaagttg gtttaccacc gtgtgactca
     9901 atacttcttc ttccaacaat ggttgaaatt gaaagcttac gctaacgaca accacattga
     9961 aatcgttggg gacatgccaa tctacgtagc ggaagattca agtgatatgt gggcaaatcc
    10021 acatctcttc aaaacagatg tcaatggtaa ggctacttgt atcgcaggat gcccaccaga
    10081 tgagttttct gtaactggtc agctttgggg taacccaatc tatgactggg aagcaatgga
    10141 caaagacggc tacaaatggt ggattgaacg cttgcgtgaa agcttcaaaa tctacgatat
    10201 cgttcgtatc gaccacttcc gtggcttcga atcttattgg gaaatccctg ctggttccga
    10261 tacagcagca cctggtgagt gggtgaaagg tccaggctac aagctttttg cagccgttaa
    10321 ggaagaactt ggtgagctaa acatcatcgc agaagacctt ggcttcatga cagatgaagt
    10381 gatcgaattg cgtgaacgta ctggcttccc aggaatgaag attcttcaat ttgccttcaa
    10441 cccagaagac gaaagcattg atagcccaca cttggcacct gctaactcag ttatgtacac
    10501 aggaacacac gataacaata cggttcttgg ttggtaccgt aacgagattg atgatgcgac
    10561 tcgtgagtac atggctcgtt acacgaaccg taaagaatac gaaacagtgg tacacgctat
    10621 gcttcgtaca gtattttcat cagttagctt tatggcaatt gcaactatgc aagatttact
    10681 agaattggat gaggcagctc gtatgaactt cccatctacc cttggtggaa actggtcttg
    10741 gcgtatgact gaagatcaat tgacaccagc tgtcgaggaa ggtttgcttg acttgacaac
    10801 aatttatcgc cgaattaatg aaaatttggt agatttaaag aaataagaca ataatcagga
    10861 gacaactaaa catgttatca ctacaagaat ttgtacaaaa tcgttacaat aaaaccattg
    10921 cagaatgtag caatgaagag ctttaccttg ctcttcttaa ctacagcaag cttgcaagca
    10981 gccaaaaacc agtcaacact ggtaagaaaa aagtttacta catctcagct gagttcttga
    11041 ttggtaaact cttgtcaaac aacttgatta accttggtct ttacgacgat gttaaaaaag
    11101 aacttgcagc tgcaggtaaa gacttgatcg aagttgaaga agttgaattg gaaccatctc
    11161 ttggtaatgg tggtttggga cgtttggctg cctgctttat cgactcaatt gctactcttg
    11221 gtttgaatgg tgacggtgtt ggtcttaact accactttgg tcttttccaa caagttctta
    11281 aaaacaacca acaagaaaca attccaaatg catggttgac agagcaaaac tggttggttc
    11341 gctcaagccg tagctaccaa gtaccatttg cagactttac tttgacatca actctttacg
    11401 atattgatgt tactggttat gaaacagcga ctaaaaaccg cttgcgtttg tttgacttgg
    11461 attcagttga ttcttctatt attaaagatg gtatcaactt tgacaagaca gatatcgctc
    11521 gcaacttgac tctcttcctt tacccagatg atagtgaccg tcaaggtgaa ttgctccgta
    11581 tcttccaaca atacttcatg gtttcaaacg gtgcgcaatt gatcatcgac gaagcaatcg
    11641 aaaaaggaag caacttgcat gaccttgctg actacgcagt tgtccaaatc aacgatactc
    11701 acccatcaat ggtgattcct gaattgattc gtcttttgac tgcacgtggt atcgagcttg
    11761 acgaagcaat ctcaattgtt cgtagcatga ctgcctacac taaccacaca atccttgctg
    11821 aagcgcttga aaaatggcct cttgaattct tgcaagaagt ggttcctcac ttggtaccaa
    11881 tcatcgaaga attggaccgt cgtgtgaagg cagagtacaa agatccagct gttcaaatca
    11941 tcgatgagag cggacgtgtt cacatggctc acatggatat ccactacgga tacagtgtta
    12001 acggggttgc agcactccat actgaaatct tgaaaaattc tgagttgaaa gccttctacg
    12061 acctttaccc agaaaagttc aacaacaaaa caaacggtat cactttccgt cgttggctta
    12121 tgcatgctaa cccaagattg tctcactact tggatgagat tcttggagat ggttggcacc
    12181 atgaagcaga tgagcttgaa aaactgttgt cttatgaaga caaagcagct gtcaaagaaa
    12241 aattggaaag catcaaggct cacaacaaac gtaaattggc tcgtcacttg aaagaacacc
    12301 aaggtgtgga aatcaatcca aattctatct ttgatatcca aatcaaacgt cttcacgagt
    12361 acaaacgcca acaaatgaac gctttgtacg tgatccacaa ataccttgac atcaaagctg
    12421 gtaacatccc tgctcgtcca atcacaatct tctttggtgg taaagcagct ccagcctaca
    12481 caatcgctca agacattatc catttaatcc tttgcatgtc agaagttatt gctaacgatc
    12541 cagcagtagc tccacacttg caagtagtta tggttgaaaa ctacaacgtt actgcagcaa
    12601 gtttccttat cccagcatgt gatatctcag aacaaatctc acttgcttct aaagaagctt
    12661 caggtactgg taacatgaaa ttcatgttga acggagcttt gacacttggt actatggacg
    12721 gtgctaacgt ggaaatcgct gagttggttg gagaagaaaa catttacatc ttcggtgaag
    12781 attcagaaac tgttatcgac ctttacgcaa aagcagctta caaatcaaac gaattctacg
    12841 ctcgtgaagc catcaaacca ttggttgact tcatcgttag tgatgcagtt cttgcagctg
    12901 gaaacaaaga gcgcttggaa cgtctttaca atgaattgat caacaaagac tggttcatga
    12961 ctcttcttga tttggaagac tacatcaaag tcaaagagca aatgcttgct gactacgaag
    13021 accgtgacgc atggttggat aaagtcatcg ttaacatttc taaagcagga ttcttctcat
    13081 ctgaccgtac aatcgctcag tataacgaag acatctggca cttgaactaa tactcttcga
    13141 aaatctcttc aaaccacgtc agctttatct gcaacctcaa agcggtgctt tgagcaacct
    13201 gcggctagct tcctagtttg ctctttgatt ttcattgagt ataagataca aatttatact
    13261 aatacatttt gtaaaaaagc gagtttcgat tgaaattcgc ttttttaaat gctgtggatt
    13321 tgggtcaatc ttgtctaaaa atagggaaat cctagataca gtgaaggctt taaatgctgg
    13381 tttttactgt cttcagcctt atattttttc gtagttggtt acctcatatc tcttgtattc
    13441 gcttacataa agtattataa tataattgta ggaaagaagg tgtttttatg atatacacac
    13501 ttaaattggt gttgtttatt acctttcttg taataagctt gttacctgat aagatttttg
    13561 gaaaaaataa aaaaaatttg gaaaatagtt tttgcaatat tgacggcagt ggcagcattg
    13621 tcatttatgt actaagttat tttaagaatg tagggaaata aaccctacat tctttttagt
    13681 tttttctgtt ttctaaattc tatttatcca agcgcttcaa catttcttgc ttcttcgctt
    13741 caagttctgc acgcttttct tcgatttcgg catgtttttt ctcgagttca gaacaacttg
    13801 caccattgct aaattctttt cgccatcagg agatagggtg agtcgacatg tctattactc
    13861 acccaaagca gtcctacaaa gcaggaattt tctgttactt ttttggaaat agtaacgttt
    13921 atacagcttt gacacttcgt atcaaagcgc caaacacact ccgagggatt tacagaaagc
    13981 agaaaaggaa tgatctggta taagatcatt ccttttctct ctttttcttt aagtaattat
    14041 atacaatgta cgacgaagtc gtcattgcaa tgctgatcca ccacctaaag ggaactttaa
    14101 acaacattga taagataaag aatataaaca acgaaaatac gttataccca attaatttta
    14161 ttgtatatct catgattaaa agttaatcct tccgttgtta ggaatggcat catttttatc
    14221 ccataattgt gttaaataag tccccggtga taataaattc atagcggatt ctaaagcaac
    14281 atcatttaca aaccaactac ctagatatct agaaattgct gaacgaatag cactttttgc
    14341 tgcatgtttt ccttttactt taattagatt tgcaaggcct gcagtagttc ctcctaatgc
    14401 taaagctatt gcagtatcta atagagcacc catttgatta actgtaatac cttgccaagc
    14461 tgctctaaat ggagagtatg taggtgggat tgtataatcg ccttgtaatt gtcggttaat
    14521 tacttctttg atccattgtt gtgagacgtc tggatgaaaa gattggattt cgtttgcaag
    14581 tgtattgatt tgttcttctg ttagagaagt gacaggttga agttccatat ttgtttcaat
    14641 ttgtgatact tgttcagaag cgtatacagc tgaaacactt ggaatcgctg atacaattaa
    14701 cacaattgac gtcaaaaaaa ccgaaataaa tttcattaat ttgttcatga acttttctcc
    14761 tttttatttg tatctgctta cattttatca tatactgtta ttatagtcaa aaaaatatgc
    14821 tattatgtta aaaaaatatt tttcaaaata taaatggacg gatttatttt ggattttatt
    14881 tgttattttg acctgcctct atattggtaa ccatgatttg tttactctca atcatcaaga
    14941 attctctttt cgtggtagcg tttggggtct ggtactggcc ttatatcact tattgttcat
    15001 tgataagttt gtaatttcga atcgaaaata aagattagaa ctatgattga ctggctactt
    15061 ttaatattga ttttggagga agattttgtc tctattattt attattttaa atttatttat
    15121 tttgtataag atctattctt tgaggcggga aaaatcgaaa tacttgattt atatggtcta
    15181 tatcatattt ggggtaaatg tagtatatgg tattcaatgg ttattaaaag aactgatttc
    15241 aactatttcc ccttaatgtg tatggaaact ataacaaaac gcataagatt aaggtttgtg
    15301 tacctgttct tatacgtttt tgtaatattg aagattttcg gtaagtttta tacctttggg
    15361 aagtctagtt tagaatgctt tcccaaccag aatctctgct tcgatggtaa tctctgtcag
    15421 ttggctccag tcaatcttgc tctggtcaac gtgaaagagg agaggagtca tactgagtag
    15481 ggcttggagt tgttctgctg tgatagtctt agtcagagag gcagtttgac tagataggat
    15541 ggtaaagtgt tcctggaaat gctccttgat atcttggtta gaatactcct tgtttgtcag
    15601 ctggtcctgt actctttgac ggatttcttt gaggtgattt tcagttggga taacctttat
    15661 caagataccg tctttggata aaacgcgacg aaattctcca tagttggcag gtgagaagat
    15721 atcaagcaga atatccatgc tagcgtcttt tataggaagg cgtgccaagt cgccaacgaa
    15781 ccaattgact gcccagttgg gttcactttt agcagcgatt tggactgaat ctttggagat
    15841 gtcaaaggca tagaaagttt tttcagagtg actttcttgt agtttgcgag aatagaatcc
    15901 ttcaccacaa ccgatatcca aaattgttgt ggtagttttt gagcttgcaa gcaagtcaga
    15961 tacagcatct aagatagctt ggtaaaagcc ggcttctaag atttgttgac ggttttgaaa
    16021 attttccttg tcatagttag cagattgctt gatttgaggt gctagattga catagccaaa
    16081 tttcgccaag tcaaaagaat gacggttgca gcacttgaaa ttagtctcta acagagtcag
    16141 attttcttga cagataggac aggcaaagga agtcgcagaa gcaaaacgct gaagtttggg
    16201 cttgagattt gtattcatag tttaagtgta tcaaaagagg caaatgaaag caactttagg
    16261 aataagtaga ttcagtagaa ataaaactaa ttctccaatt tatagaatga aattgctttt
    16321 atatctaaat tgctatataa taatgataag gaggaaataa gtatgttaaa agaagtatta
    16381 accgttgcaa aagttgcgaa aaaatcttca ttatttttgg gtggtgtcgc atttggtacc
    16441 cttggtttga aaatcttagc aagtaaggaa gctaaaaaag gttattctaa agctttggct
    16501 aaggcttaca agttgaaaga cgagctagat gcatctgttt ctgttgtgaa gcaacatgga
    16561 gacgatgtct tgcaagatgc caaatatttg tacgagcaag agaaaaaaga agagcaatta
    16621 gatagcctta taggtgaata atatgtcttt taaagtgcta catagaggat accaacatat
    16681 ccgactatca tcttcttttt cacttacctt ggatattcaa gactatcttc gttccttggc
    16741 gagagatgaa aaggggattg agtctatcca gttttacatg gatcaacagc actttactct
    16801 acgcataaaa gaaggctttt ctgtattaga taatgcagaa gcctttttaa aaagaattga
    16861 taaagggaaa gtttctgagt tgatgactct tcccattcgt agagaagaga gtgcttattc
    16921 tattgtttca ggtgcagcgg ttaagcgtgt actttttcgt agttttgtgc cgtatcctat
    16981 tcgctatata tggacttgtt atcaggcttt gggttatatt agagaagcct atcaaacact
    17041 agcgcgtaag gaactaacga tggaagtctt ggactgttcg gctattttat tgtccttgtt
    17101 tatgaaccaa tccaagacag ctagcaatat catgtttatg cttgatttgg ggaatcattt
    17161 agatcagtgg tccttgaaaa aaactgcaac agatttagaa cagagtcttc ttgcaaaaga
    17221 gagcgatgta ttcctagtac agggcgatac ggttgttagt atcaagagtt ccgatgttca
    17281 aataggagat gtcttgatct tatctcaagg aaatgaaatt ctgtttgatg gacaagtagt
    17341 ttcaggttta ggtatggtca acgaaagttc cttgacagga gagagttttc cagttgaaaa
    17401 aagagagtct gatttggttt gtgcaaatac agtattagaa actggagagt tacgcattcg
    17461 tgtaacagat aatcagatga acagccgtat tttacagctg attgagttga tgaagaaatc
    17521 tgaagaaaac aagaaaacga aacaacgcta tttcatcaag atggcggata aagtcgtcaa
    17581 atataatttc ttgggggctg ggctgactta cctattgaca ggttcttttt ctaaggctat
    17641 ttctttccta ttggtcgatt tctcctgcgc tttgaaaatc tctactcctg tagcttattt
    17701 gacagttatc aaggaagggt tgaaccgtga aatggtgatt aaggatggag atgttctgga
    17761 gaaatatctg gaagttgata ctttcttgtt tgataagaca ggaacaatca caactagtta
    17821 tcctatagtt gaaaaggtgt taccttttgg agactatagt gaggaagata ttctcagaat
    17881 cagtgcctgt cttgaggaac acatttatca tcctattgct aatgccatcg tcaagcaagc
    17941 tgagatagag ggaattgaac atgaggaaat gcatgggaaa ctccaatata tcgcaagcaa
    18001 ggggatcaaa tctcatatag atggccaacc agttcttatt gggaattatg tcttgatgca
    18061 ggatgagcag attcatatca gttcagaaca aaatgcttta attgaagagt acaagagtca
    18121 ctacaatctc ttattcttgg cttatcaaaa tgaattgatt ggaatgttct gcattcatac
    18181 tcctttgaga aaagaagcaa aaacagcctt ggataaactt aaggcacagg ggaaaaaatt
    18241 gattctggca acaggagaca ccttgattag gacagaggaa ttagtcaaag atttgccctt
    18301 tgatcaggtc tatacagact tgaaacctga tgggaaattt gagttagtag agaaactgca
    18361 gaaagcaggt cacactattt tgatggttgg agatggattg aatgactcag cggctttaac
    18421 tctatcagat atcggtgtgg tgatgaatga gagtgcagat atttctaagc agatgagtga
    18481 tatcttattg ttagataatc gtttggattt cttccaagag ttggattcgt tatcatcatc
    18541 tttgcaaaca ctcatcaaga aaaatattca ggataccgtt gtcgtaaata gtagtttgat
    18601 tggctttggc ttatttaatt ggttcagtcc ttcaaatctc tctatcttac ataatctaac
    18661 aaccttgcgc attgtcctgc gtagcctgtc tattaaaaat agatagatga gagttattaa
    18721 cagcaaaaag gagttacctt tctcgaggtt aactcctttg tttatagata aatgttgaat
    18781 agtttagtaa gtcaatacaa agtatttttt cttcccacga cggataacag tcagttcatt
    18841 ttctaactta tcagcgtcac tcaagacata gtcaaggtct tggatgcggt cgccgtttac
    18901 gtagatggct ccgttttgga cgtcttcacg ggcttggcgt tttgagttaa ctataccaga
    18961 tgagacgagc agttccacga tattgttgtt ttcgtctgcc tgtacttggt agtttggcac
    19021 accacgaagt ccttgtttga gctctttgac agaaaggttt ttgatgtttc ctgcaaagag
    19081 ttgctcagtg atgttaagtg cttctttgta ggcttcttct ccgtgaacaa gtgtaacaac
    19141 ttcacgagcc aagacttttt gagccaagcg ttcgtgtggc gctgcttcaa attgtttacg
    19201 aatatcttca atctcatcaa gtgacaagaa agtaaagatt ttcaagaagc gaacagcgtc
    19261 agcgtccatc acgttcatcc agaattggta catttcgtat ggagaagtct tttcgggatt
    19321 gagccagacg gcatttcctt ctgatttacc aaatttctta ccagttgcat ctgtgattag
    19381 tggaacagtg ataacgtgac cagtcttgtc cgccttacga cgaagcaatt cggtaccagc
    19441 tgtcatattt ccccactggt cagaaccacc gatttgaaga gtgacattat ggtcttggtt
    19501 aaggacgaag aagtcgtacc cttgcatgat ttggtaagcg aactcagtgt aagaaattcc
    19561 tgtttcgatc cgttttttaa cagattcctt actcatcatg tagttgaccg tgaagtattt
    19621 tccaatatca cggaggaagt caatgaagct gatgctgcca aaccagtcgt agttgttgac
    19681 catgacagcc ttgttttcgc cattttcaaa gtcaagaaaa cgagaaagtt gtccttggat
    19741 agacttgacc cagccatcta ctgtgtcttt tgtttggaga ctacgttcag catctttgaa
    19801 ggacggatct ccgatgagac ctgtagcacc gccaacgagc gcataaggtt tgtgacctgc
    19861 tagttgcaag cgacgacttg tcaagattgc gacaaggtgg cctaggtgaa ggctgtcagc
    19921 agttggatcg tagccagtat aataagaaac ttgaccttct tctagggctt tacgcaaagc
    19981 ttcttcatca gtcgtttgaa atatcaaacc acgctctttt agctcatcaa aaatgtgcat
    20041 gtgtcttttc tcctttttaa aattattgtt tctacctatt gtatcacaaa cttgggcaat
    20101 agcctagcag aatagggaag aaagtggcta ttttattgaa aatttccctt ttgtggtata
    20161 atagataaag tgaggaaatc catgcaaaat caattaaatg aattaaaacg aaaaatgctg
    20221 gaatttttcc agcaaaaaca aaaaaataaa aaatcagcta gacctggcaa gaaaggttca
    20281 agtaccaaaa aatctaaaac cttagataag tcagccattt tcccagctat tttactgagt
    20341 ataaaagcct tatttaactt actctttgta ctcggttttc taggaggaat gttgggagct
    20401 gggattgctt tggggtacgg agtggcctta tttgacaagg ttcgggtgcc tcagacagaa
    20461 gaattggtga atcaggtcaa ggacatctct tctatttcag agattaccta ttcggacggg
    20521 acggtgattg cttccataga gagtgatttg ttgcgcactt ctatctcatc tgagcaaatt
    20581 tcggaaaatc tgaagaaggc tatcattgcg acagaagatg aacactttaa agaacataag
    20641 ggtgtagtac ccaaggcggt gattcgtgcg accttgggga aatttgtagg tttgggttcc
    20701 tctagtgggg gttcaacctt gacccagcaa ctaattaaac agcaggtggt tggggatgcg
    20761 ccgaccttgg ctcgtaaggc ggcagagatt gtggatgctc ttgccttgga acgcgccatg
    20821 aataaagatg agattttaac gacctatctc aatgtggctc cctttggccg aaataataag
    20881 ggacagaata ttgcaggggc tcggcaagca gctgagggaa ttttcggtgt agatgccagt
    20941 cagttgactg ttcctcaagc agcattttta gcaggacttc cacagagtcc cattacttac
    21001 tctccttatg aaaatactgg ggagttgaag agtgatgaag acctagaaat tggcttaaga
    21061 cgggctaagg cagttcttta cagtatgtat cgtacaggtg cattaagcaa agacgagtat
    21121 tctcagtaca aggattatga ccttaaacag gactttttac catcgggcac ggttacagga
    21181 atttcacgag actatttata ctttacaact ttggcagaag ctcaagaacg tatgtatgac
    21241 tatctagctc agagagacaa tgtctccgct aaggagttga aaaatgaggc aactcagaag
    21301 ttttatcgag atttggcagc caaggaaatt gaaaatggtg gttataagat tactactacc
    21361 atagatcaga aaattcattc tgccatgcaa agtgcggttg ctgattatgg ctatctttta
    21421 gacgatggaa caggtcttgt agaagtaggg aatgtcttga tggacaacca aacaggtgct
    21481 attctaggct ttgtaggtgg tcgtaattat caagaaaatc aaaataatca tgcctttgat
    21541 accaaacgtt cgccagcttc tactaccaag cccttgctgg cctacggtat tgctattgac
    21601 cagggcttga tgggaagtga aacgattcta tctaactatc caacaaactt tgctaatggc
    21661 aatccgatta tgtatgctaa tagcaaggga acaggaatga tgaccttggg agaagctctg
    21721 aactattcat ggaatatccc tgcttactgg acctatcgta tgctccgtga aaagggtgtt
    21781 gatgtcaagg gttatatgga aaagatgggt tacgagattc ctgagtacgg tattgagagc
    21841 ttgccaatgg gtggtggtat tgaagtcaca gttgcccagc ataccaatgg ctatcagacc
    21901 ttagctaata atggagttta tcatcagaag catgtgattt caaagattga agcagcagat
    21961 ggtagagtgg tgtatgagta tcaggataaa ccggttcaag tctattcaaa agctactgcg
    22021 acgattatgc agggattgct acgagaagtt ctatcctctc gtgtgacaac aaccttcaag
    22081 tctaacctga cttctttaaa tcctactctg gctaatgcag attggattgg gaagactggt
    22141 acaaccaacc aagacgaaaa tatgtggctc atgctttcga cacctagatt aaccctaggt
    22201 ggctggattg ggcatgatga taatcattca ttgtcacgta gagcaggtta ttctaataac
    22261 tctaattaca tggctcatct ggtaaatgcg attcagcaag cttccccaag catttggggg
    22321 aacgagcgct ttgctttaga tcctagtgta gtgaaatcgg aagtcttgaa atcaacaggt
    22381 caaaaaccag ggaaggtttc tgttgaagga aaagaagtag aggtcacagg ttcgactgtt
    22441 accagctatt gggctaataa gtcaggagcg ccagcgacaa gttatcgctt tgctattggc
    22501 ggaagtgatg cggattatca gaatgcttgg tctagtattg tagggagtct accaactcca
    22561 tccagctcca gcagttcaag tagtagttct agcgatagca gtaactcaag tactacacga
    22621 ccttcttctt caagggcgag acgataattc tctaaatgaa gtggccaatc aatggattgc
    22681 cacttttttc ctttcgtgtt acaataaggg tatgaatcag tatcagaaaa agattgttaa
    22741 cggaaaaatt tattcgctcc tatccggctt aatatgggga atctgtggaa ttttaggaga
    22801 gtacttcttt actcattatc aggtgtcttc gggctggatt acctctatgc gtttgacact
    22861 ggcagggagt attgtactca tttggtctgc aatacaatta aaatcgcaag tgctagatat
    22921 ttggcgagac aagaaaaatt acctgccctt tttagcctat gctattttgg ggattttttc
    22981 agtccagtat tttttctatc tctgtgtaga atactcaaat gctacgacag caactatttt
    23041 acagtttatt agccctgttt ttatcctctt ttacaatcgc ttggtttatc aaaaacgagc
    23101 gtcaaaaagc gctgttttct atgttttggt tgccatgctg ggtgtttgct tgatggcgac
    23161 aaagggagat ctctctcagt tatccatgac gccgctagct cttataacag gtttgctgag
    23221 tgccatgggt gttatgttta atgttatctt gccccaacct tttgctaagc gttatggttt
    23281 tgttcctacg gttgggtggg ggatgatttt ggcaggtttg tttagcaatg tcctctcgcc
    23341 ggtttatcag ctttccttta ctcttgatat ttggagtatc ttgatttgcc tcattatcgc
    23401 tttctttgga acggcttttg cttttttcat ttccatgaag gctgtgtcct tggtttctcc
    23461 tttggtggtt tccgttatca gtgccagtga acctctctct tctgctctct tgagtgtttt
    23521 gttcttagga ttagtagtgg attggtccct ccttctagct atagccttga ttattttacc
    23581 catgatattt ttgtctatag aagaagcgaa agaaagtaga taaaaagtct tttcttaatt
    23641 ctaaaagtgt gctatactag aatagtcaat aaaacacggg gagatagttg tgaagagtgt
    23701 ttttaggttg tatcggtagg ggcttgcttt taccgacagc acgttttatc tcacatccct
    23761 aaaaaatcat acctaaaaac agacaaaaag gcttcaaatt tgaggccttt tttggtagaa
    23821 taggtatcat tataacgaac caggaggcac ctatgactgc tacaaaaatg aacgctcaag
    23881 aaattatcca atttatcgcc aatgctgaaa agaaaaccag tgtcaaagta acctttgagg
    23941 ggcaactcgc aacttctgtg cctagctctg ttgtcaaact aggaaatgtc ctattcggag
    24001 actggaagga cgtggctccg cttcttgaag gtttggtaga aaatcaagat tatgttgtcg
    24061 agcaagatgc tcgtaattct gcagttcctt tgctagataa gcgtgctatc aacgctcgta
    24121 tcgagccagg tgctattatc cgtgaccagg tggaaattgg tgacaatgct gttatcatga
    24181 tgggagctgt tatcaatatc ggtgctgaaa tcggtgctgg aaccatgatt gacatgggtg
    24241 ccatccttgg tggccgtgcc atcgttggaa aaaatagcca cgttggtgca ggtgcagttt
    24301 tggcaggtgt gattgagcca gctagtgctg aaccagtccg tgtcggagac aatgttctca
    24361 tcggggctaa tgcagtggtt atcgaaggag tccaaatcgg tagtggttca gttgtcgcag
    24421 caggagctat tgttacccaa gatgtcccag aaaacgtggt agtagcaggt gttccagctc
    24481 gtattatcaa agaaattgac gcccaaaccc aacaaaaaac agcgctagag gatgcgcttc
    24541 gtaccttgta attgtaaaag taaaaaagag gcggaaccct ttttccagcc tctttctgct
    24601 atatcggagg acagatagat gttagatttg attcagacta gacgagattt acaccagata
    24661 ccagagattg gcttggagga gttcaagact caggcttatt tgctggatgt gattgagaaa
    24721 ttgactacgg gcaaggattt tgttcaaatt cgtacttggc ggacagggat tttggtctac
    24781 ctgcagggaa gtcagccgga gcgaaccatt ggttggcgga cagatattga tggcctgcct
    24841 atcgtcgaac aaacaggtct accttttgct tctcaacacc aaggtcgcat gcatgcctgt
    24901 ggtcatgatt ttcatatgac cattgcctta ggctgtcttg agcgcgccct tgaggagcaa
    24961 cccaagaata atctgctctt tctatttcag cctgctgaag aaaatgaagc tggtggtatg
    25021 ctcatgtatg aggacggtgc ttttggagat tggttgccag atcaattcta tggtctccat
    25081 gttcgtccag atttgaaagt cggccagatt gcgactaata ctcatacact ctttgcagga
    25141 acttgcgagg tgaagacccg tttcaaaggc aaaggtggcc acgcagcttt tcctcatgaa
    25201 gccaatgacg ccttggtggc ggctagttac tttgtgaccc aagtgcagtc agttgttagc
    25261 cgcaatgtca acccaatcga gggagcagtg gtgaccttcg gcgtttttca agctggaacc
    25321 accaacaatg tcatcacaga cacagctttt ttacatggaa ctattcgtgc cttgacacag
    25381 gacatgagtc tcttggtgca aaagagggta aaaacagttg cagaaggggt tgcagctgcc
    25441 tttgatatgg aagtcgaagt ggaactcaaa caaggtggat acctacctgt tgagaacaat
    25501 ccagccttgg cgtgtgaact gatggacttc tttgacgaaa aagacggaat cgagttgatt
    25561 gatatcgaac ctgctatgac aggcgaggac tttggttatc tcctttcaaa ggttgatggc
    25621 gtgatgtttt ggctaggtat cgatagtccc tacgctcttc atcaccctca aatgagtcct
    25681 aaggaagaag tcttagctat tggggtggct gcggtgtcta gtttcctgaa aaagaaggca
    25741 gcagaataga gggcttgtct atgaaatcgg aattacgcaa gcaagtcttg catgaaatga
    25801 aggctatatc tcaagagcaa aaacaggcta tagaccaagc tttaaccgag cggcttttac
    25861 accatccctt ctaccaagaa gccaaggtca tcgcaaccta cctctctttt cctcatgagt
    25921 ttcaaacgca ggaactgatt gagcaggcgc tgaaggacgg caagagggtt ctgacaccta
    25981 agatctatcc caaggggcgc atggactttg tggtctatga tccgcaacag ttggtaaaaa
    26041 ctgcctttgc cttactggag tcacagggag atttggaagt ggtggatgta tctcagattg
    26101 atttgattca tgttcctggc ctggctttta cgacggatgg atatcggatt ggatatggtg
    26161 gaggttatta tgaccgctat ctggaacatt tttctggtca tactttgagt acggttcatc
    26221 cttgtcaaat tcaggacttt atacctgaaa accatgatat tcctgttcag gaggtattaa
    26281 ttgatgaagg aaatctttga tagacgttac cctgtgacga gtttcttcct cttagtgacg
    26341 gccttggtat ttttactaat gttggtcact gcaggcggaa actttgacag ggcagataca
    26401 ttatttcgat ttggagccat gtatgggcca gctattcgcc tctttcccga gcaggtttgg
    26461 cgtctcttgt ctgccatttt tgttcatatt gggtgggaac atttcattgt taatatgctt
    26521 tcactttatt atcttggaag gcaggtagag gagcttttcg gctctaagca gttctttttt
    26581 ctctatctct tatcaggaat gatgggcaat ctctttgttt ttgtatttag tcctaaatcc
    26641 ttagcagcag gcgcctctac ctctctttat gggctatttg ccgcgattat cattcttcgc
    26701 tatgcaactc gcaatcctta tatccaacag ctagggcaat cctatctgac actttttgtg
    26761 gttaacatta ttggaagtgt tctgattcca ggaatcagcc tagcaggcca tatcggtggt
    26821 gcagttggtg gcgcatttct agcagttatc tttccagtta gaggagaaaa acggatgtat
    26881 aacaccatcc agagattagg agcggtagtc ttgttcgtag gactcgccat tttgcttttc
    26941 tacaagggaa tgggaatgtg acgaagttga aagaaaattt gtgtaatgaa aaaagataag
    27001 gcattttttg aaccttatct ttttatttta ttccttctca gtcaattctt ttccaagttg
    27061 gatgaggtaa ttcttcaaat catctttgac ttgtgggtgt ttgagggcgt agtcgatgga
    27121 tgttttcata aagccaaact tatccccaac gtcgtaacga gctcctgtaa atttacgggc
    27181 aaaaacacgc tgtgttttat taagagtatc gattgcatca gtaagttgga tttcatttcc
    27241 agcaccagga gcttggtttt cgaggatttg gaaaatttca ggcgtgagga ggtagcgtcc
    27301 gataatagca aggtcgctag gagcgtcctc tggagctggt ttttcaacaa aggtttcaac
    27361 actgtaaaga ccatcttttc cttcgccttg cggagcaata accccgtaag cagatacttc
    27421 gtcatgaggg actggcatga cagcgatagt agacgcgtgg gtacgctcgt agtcatccat
    27481 gagttgtttg gtaagtggaa cagccttttc gtctgtgata tccatcaagt catcaccaag
    27541 cataacgaca aaaggttcat ttccgacgaa agccttggct tgcaaaacag catctccgag
    27601 accgcgtgga tgagtttggc ggataaaatg cagacgcatg tcagttgttt tatcaactag
    27661 cttcaaaaga tctgttttcc ctttttcttt gaggttatat tccaattcga agtttgaatc
    27721 aaagtggtcc tcaatagaac gttttgattt accagtgaca actagaatat cttcaatacc
    27781 tgatttgaga gcttcttcca cgataaactg gatagttggt ttgtctacga ttggcaacat
    27841 ttctttggca agggccttgg ttgctggtaa aaatcgagtt cctagtccag cagcagggat
    27901 aactgccttt ctaacttttg atgtcataaa aatcctttct atagagggtt aagaccactc
    27961 attttctgct ttaaattcat tgttcatgat gtcataaatg gcatctttga tattggttcc
    28021 gtgataaata acttggtaaa tagcctgtgt aatgggcata tagactccaa gttcttgggc
    28081 tagttcatag gctgctcgag tcgttgaaat tccttcgatt accatgccca tattagcttc
    28141 tatatcagct agggattctc ctcgtccgag agcatctcca gctctccagt tacgagagtg
    28201 gatggaagtt cccgttacga tcaaatctcc cacaccagat aagccgctat aggtcaatgg
    28261 actggccccg agtgctaccc ctaggcgggt gatttctgct aaacctcgag cgatgatggc
    28321 tgccttagca ttatcaccaa atccaagacc atgtaaagct ccagcaccga cagcaataat
    28381 atttttaaga gcaccagcag tttcaacccc gataacatcc gtattggtat aaagtcggaa
    28441 gtagtgatta ctaaatagct tctgaacgta ttgagctgtt tgtaaatctt tagaagcagc
    28501 agttattaaa gttaggtcac gcacaatggt ctcttctgca tgactaggcc ctgaaacaac
    28561 gacgatatca ctacggagat gttcaggaat ttcttcttca agaatggttg ataatcgttt
    28621 atggctatca ggttctaatc cctttgatgc gtgcatgatg ataaccttat ggtccaaggt
    28681 ttgtgcaact tgctgggcaa caagtcgtgt cacttttgtt gggacaacaa acaaaatcgc
    28741 atccacatct ttcaatgttt ctgctaagtc ggtgtaggca atgatatttt cgtctagaac
    28801 gacatcttta aagtagtgct tattagtatg gtgtgtatta atttcattga tttgctcggg
    28861 aagatttccc caaatacgta cctcgtgtcc attgtcattt aagacttgtg aaagggcggt
    28921 tccccaagaa ccaggcccca agacggcgac ggtttgtttt tccatgattt cctccttgat
    28981 agagttcttt ctcttattct atcatattct aggggatttt gcacttgcat tactggggta
    29041 tggtggaaaa atacacaaaa accgagacga agggataaac tcttagtctt tagttaaagt
    29101 gagaagaaat ctgatagata gtttgattca gtatatgctt ataatagagg taaacaactc
    29161 aggaggttct tgtaggttgc gagagtttgg cgaaaaaatt aaaagattac gtttggctaa
    29221 aaaaatcagt cgttcagaat tttgtggtga tgagtctgaa ttaagtatcc gtcaattaat
    29281 tagaattgaa aatggagaat ccagaccaat actaacaaag ttaaaatata ttgctgaacg
    29341 tttggaggtt gaagattaca agttgatgcc aagttatata gagttggata aggaatacct
    29401 agaattgaag tatttcttga tgaggactcc tacatacgaa gatgaaacta tcgcccaaaa
    29461 gaaagagagt gttttgataa gatttttgaa gagtattatg ataggctacc tgaggaagaa
    29521 agatttatca tcccaaatta ttcatatctg gcactaacga actacacagt tcaaaaatta
    29581 ccagaaaagc tagttgaaat actgtccttc tggtgatttt gcttaatttc tgatgttcga
    29641 gacataattg aggagatttg tcttgatttt ttcctaaaaa agggcagact cctcccttgg
    29701 tttgatgctc gatttttaaa ataaggtgac ttattctgtt aggcatgttt tcccctgccc
    29761 tctagctcta tatggaacag ggagtatcag atttatctgg cagattgtat caaataaggc
    29821 ttgaaactgt tttgaatagg catatagact tgagaatttg agaatatgtc gtctagcagt
    29881 agagacatat tttccggcaa tatgaaggaa gagacgtcga aaacgcttga tagtcaaggc
    29941 ctttacttca tcaccagcta gctgctttaa aaagaggtag agattataag ccagacagcc
    30001 catcatcata cgtacttcat tcttaatcat ggtcgaacta tctgtcttat ccccaaagaa
    30061 tcctgctttc ctttctttga taaagttttc agcattccct cgttcacgat agaattgaaa
    30121 cagctcctca ctatctacac tgcttaaatt ggtcaaatga acttttttac aaccataaaa
    30181 aagagcactt aatcgtactc ttctctttta aggattagtt gaattaattc aaatccacta
    30241 gttctcctgt ttctaggtag actaggcgtt cacaaatgtt agcaatgtaa tcagcgaagc
    30301 gttccagatg ccctatgata taaaggtatt gtgttccatt gggaattgag gtttcttggt
    30361 ctttcataag tccaatgatt tcctttgata aggcataata atattggtca atctgttcat
    30421 ctttttgagc aatactaata gcttttgagg cttggtgcaa aggaaaggca accaataaat
    30481 cggatagcat gctgagggat aatttaccca tttggtgtaa ctgttcttcg tcaggggcta
    30541 gttgattttc ttttagttgc aaaacagctt tagcaatgcc tgccatatgg tctcccatac
    30601 gttcaaggtc tgaacaagaa gacatgatgc taatcacaaa tcgaaggtca gacacttgtg
    30661 gctgctgcaa ggccaacaaa cgggcacagg tcaattcgat agcgctttga ccttggttga
    30721 tagcatgatc cttattgata attagctctg ccatctcctt gtctttggag gctaaggcca
    30781 gtaaggtttt tgaagctgtt tcaaggacaa gttgccctag tcctaaaaag gattgttcta
    30841 attcatgcaa ttctaagtca aattgatttc tcataggttt ttccttcctt atccgaaccg
    30901 tcctgaaata tagtcttctg tgcgctgatc ttttggattg gtaaacacgt caacggtgtc
    30961 tccaaattcg caaatttctc ctgttaagaa aaaagcagtt ttatctgaaa tacgtgaagc
    31021 ttgttgcatg ttatgggtaa caatgataat cgtataatcc ttttttagtt gctgaatgag
    31081 gtcttcaatt tttaaagtgg agatagggtc taaggctgaa gtcggctcat ccattaacag
    31141 aacatcaggt tctactgcta aagctcgcgc aatgcaaagg cgttgctgct gaccgcctga
    31201 taaggacatg gcactctttt taagattatc tttgacttcg tcccaaatgg ctgccccttt
    31261 taaagatttt tccactaagg catctaattg ttttttgtct cgaataccat gtgtccttgg
    31321 accataagcc acgttatcat agatagacat ggcaaaggga ttaggctgtt gaaaaaccat
    31381 ccctacacgc ttgcgtagct gattaaggtt gaatttgcta ctataaatat cttgctcatc
    31441 taagaggact tggccttcaa tatggcaaga aggaaccaaa tcgttcatcc gattaagggt
    31501 ttttagaaaa gttgatttgc cacaaccaga tgggcctatc aaggcagtaa tctgtctttc
    31561 tggtaattga atcgaaatat tttttaaggc ttgaaaatcc ccgtaaaata agtctaggtg
    31621 tctgactgaa aatgttccca tactaggaag ctcctttcac aagtttccga gataataagc
    31681 ttgatagagt atttatcatt aaaacagtaa taattaaaat cacgccggta gcataggctt
    31741 cattgacatg taacccctca cttgacagca tatacatatg tagggctaga gaacggcctg
    31801 aagacatgag actacttggc gtattggtag aggtacctaa tgtatacatg agggcagctg
    31861 tttcaccaac gatacggcca atagctagta tcactccagc taaaatacct ggcatggcaa
    31921 ctggtagaac aattctaaaa acagtccgta acttacctgc cccaagtcca taacttgctt
    31981 gacgcatgct atcactaaca gataaaaggg cttcttctgt tgagcgaata atgactggca
    32041 acaccatgat aactgaggtt aagattcctg ataacagaga gtattgaaaa cctaagaaga
    32101 ctacaaagaa gagcatgcca aacagaccaa aaacaatgga aggaatccca gacaaggtat
    32161 ctgaggccaa tcgcatgatt ttaacacaaa gggaatcttt ttttgtatat tccacaagat
    32221 aaaaaccagc aaaaatccct atgggcaaag ctaaaagaag agcaccaaaa accagaataa
    32281 cggtggaaat aatcgctggc ataagggaaa tgttctcaga agtataagtc caagaaaaga
    32341 gggatagact tagatgaggt aagcctttga tgaggataaa accaatgatt aaaaagagag
    32401 agccaaaggt taaagctgaa aaacaataaa cgagaagttt tagcaggtat ttactcataa
    32461 gatgattttc ctttcaagta ggcaaagtag gcattaatca agagaataag gaaaaagaga
    32521 actgctgagg ttgcaataag ggcttcccta tgctgacctg atgcgtaagc catttccaga
    32581 acaatattgg ttgttaaggt tctggttcct gaaaagagtc cacttggaat aattggctgg
    32641 ttgcctgcca ccaaaataac tgccatggtt tcacctactg cgcgaccgat tcctaaaata
    32701 actgctgata aaataccaga tctcgcagct ggcaagatga cactaaaaat actccgttca
    32761 tgactagctc ctagagccaa gctaccagaa taatacgttt tgggaactgt tcggatagca
    32821 gattctgaca aactgataat ggttggcaaa atcattattc ctaatagtaa cgaagcggtt
    32881 aggacattca tgccatttcc taaaaaggtt ctaatccaag gcaccaataa ttgtaggccg
    32941 aaaaaaccat aaacaataga tggaatggct gccatcaagt tgatagctga ttttaagaag
    33001 ccatagacgg gctttggaca ataataaacc ataaacaccg atgtcaagat gcctgttggc
    33061 accccaatca caatcgctcc taaggtaatt aataaggaac caacgatcat tggtaaaata
    33121 ccatagcttg ccggaatgtt cgttggcgac caatcactgc ctaataaaaa acgggcaaag
    33181 ccgtagttag ccatgaaagg taagccatta ctaaaaataa agaaacagat tagcaaaata
    33241 gctacaacag ctactgttgc actcatgaaa aaaattgccc taaaaactgc ttctttgaag
    33301 gcttgttttg tcacatcttg tcctttctag tgaagaaagt aagggagata cgacacctcc
    33361 ctacttgcct tctttatctt attgtacgat gaaacgtctg catctcttta gagatttatg
    33421 gagcaaacat tttatttaat cttgtcccag gtggttaatt tgccactaaa aacgtctgca
    33481 agttcagcca tactgacttg gcttgcctta ttgtcattat tgaccacaac agcaataccg
    33541 tctaaagcaa tagcatcatg ggtgagactc ttaccttctt caggagttaa ttccctagaa
    33601 accataccaa tatcagcggt tttctcctta acagcggtaa tacctgctga agacccatta
    33661 gaggtaatat caatcgtaac ttctggattt tcttttttat aagcttctgc taatttttcc
    33721 attaaagaag atactgaagt ggaacctaca acagacaact tgcctgataa gtgttggctt
    33781 gtatattctg tggtttcagt tttagcttca ataaatttat tatctgtgac cacttgttga
    33841 ccttgtttgg agtggataaa gctgataaaa tcttgaccta gcttggaaag attagaagac
    33901 caaacaatgt tgaagggacg ttgaagaggg tattcaccat ctaaaactgt gtctcgacta
    33961 gccttgacac catcaatctc taaagccttg acagatttcg ttaaagatcc caaggagatg
    34021 tagccgatag cattagcatt cccttgaact gctgagagaa caccttctgt actattttga
    34081 atcacagctg ttttggcagt gttgtcaatt tttttatcac cgtctttttt gagaatccct
    34141 gtgatttctg tgaaggcacc ccgtgtccca gagccatttt ctcgtgaaat cacctcaatc
    34201 gttcctgaag ctgactgttt ggaagtagat gactgattgc cacaggcaac aagcccaaat
    34261 cctgataagc caatggctgc aagagtaagt atttttttga atttcataat aatcaccttt
    34321 atctctatgt atttttcttg tgtaggctta ctacatttat agtctaacaa gtctttgtaa
    34381 aggtttatcc ctgattcatg taaagattgt gtaaagaatc aaaaaaagcc acttttgaaa
    34441 aatggctgct cctaaaaata gctttaaaaa ttattagtcc tgtgcgaaag attggttagg
    34501 aagaaaaatc gtgaagcaac tgcctctgcc aagctgactc gtcaccgtga cttggccacc
    34561 taataattga ctgagttctt tgacaatggc aaggccaaga ccagtgccac cagtttgtct
    34621 gcttcgacct ttattaactc ggtaaaaacg ttcaaaaata cgatcctgct ctaattgact
    34681 aataccaatc cctgtatctg atacagaaat cttaatgcct tcgttcacct tttgggtctt
    34741 gacctcaatt tttccccctt gttcagtgta acggatggca ttggataaaa gattgagtaa
    34801 gatttgggaa agtaattgac tatctgatac gagggtgaca tcatctggca cctgcacctt
    34861 tagctgtaaa tccttcttct tgagctgagg ttgcaagctt tgagtcaaat cctgtacaaa
    34921 ttctgccaaa gaaagggtcg tccattgtat aggcatttgt tgagccttag ataaggtaag
    34981 aagatgctca acaatatgct caagacgcaa gctttctttg taaataatgt ctagaaagtc
    35041 atccttgagc gcttcttctt cagctgacat ccccttaatg gtttcagcaa agcccttaat
    35101 cgaagtaact ggtgtcctca attcatggga ggcatttgag acaaaggcta aatttaactt
    35161 ttcataagtt ctaatcgttg ttaaatcata tagcaagacg agcacagctt ccacagattg
    35221 ggtggggcta aaaacgggaa ctgctgtcac ttctaaaatc aagtcaccct catgaaaccc
    35281 acttacttct tgttttaacc ttgttttttg atcaaaggct tggtgaacta aattccgaat
    35341 atccatccgt ttgaggtcat caagtgaact tatgtcgccg tccacatcgg gaaaataatg
    35401 aggcagagag cgactggata ataacatctg accttgagcg gaaactaaaa acgtccccat
    35461 ggttaggtgc gacagaagaa cctccattgt ttcggctagg tccttgtatt gctgatcctg
    35521 ttgggagact ttggttttta ggccagacac atactgagcc aaagacttta agtcttcttg
    35581 ccctttttct aaaaagtatt cactactggt caagagaggt tggtgcaagg tctcaaaagc
    35641 aacttcccat ttccaaaggc aaaagagcca gtagccacct agtcccaaag aaagggctag
    35701 aagaaagaga ccgatgcctt tactgatcca agttaatgcc atccctgcaa tcagaatgag
    35761 gctaacactt agattgacta gccaaaattg aaggtagcgt ttcatctata actccttgaa
    35821 cttataacca taaccccgaa tggttcgaat aaattgaggg gctttaggat tgtcttcaat
    35881 tttttccctc aacttaccaa tatgaacgtc caccaaacgt gtttcctgcc caaagtcata
    35941 cccccagata cgttccaaaa gacgctctct agtcagtgtc atgttgggat gtttcataag
    36001 atagagcaag agttcaaatt cttttggggt caaactcagt aacttattcg ccttgtagac
    36061 ttcatgacgc tcagggtata ctttcaaggt cccaaatagc caagaattgt cagcgatatt
    36121 atctgaatca tctccttctt gttttccttt agttcgcctg aggacagcct tgacacgcgc
    36181 cagtaattct ctagggctaa aaggcttggt caggtagtca tcagccccta attccaaggc
    36241 caaaacctta tcaaattcat cacttttcgc agaaaccatc ataattggag ttttgacgcc
    36301 tttggctctc agccgcttac aaacttctat gccatctaat tgtggtaaca tgatatcaag
    36361 caagataaaa tcaaagggtt ctgtttctgc caaagctaag gccttccgtc catttgttac
    36421 caattgagta gaaaagcctt ccttacttaa atggtagtca agcaatttca gaatgtgttc
    36481 ttcatcatcc actaataaga cttgttttgt catctattat ctcctattgg taacattata
    36541 acacaattat cagaaatcct aacattgcta aatcagatta aatttgctta tcaagactag
    36601 tatctggtca aacgctcaat catctccttg tgctctggat aggtcgccag tagatctacc
    36661 ctttcaaata attcaaaatc ctcaaattca aaaccaggag caacaagaca agaaaccaga
    36721 gcatcatcct tatcaactgt tgatccccaa atagtgccct taggaacaca gtagtgaagt
    36781 tgttgccctt tggatatgtc caggcctaaa gtgactgctt cgtagtgacc atctgctgtg
    36841 atcatgtgaa cagtaagtgg ggatcctgca tgaaaatacc agatttcatc tgctgtcaat
    36901 cggtgaaaat gtgaaggatt cgtttcttct taataagaaa taaatactgg tataaagcgc
    36961 ccttccctta ccagcaaggt ttatagtgtc tgaagctttt tttgtttgtc taaaatagcc
    37021 accttcaaca tggggagcta actctagagt tcttatcaag tcttctttat ccgtcggagc
    37081 caatgggttg aagtaactct tgttcaaagt ggttttacga tttcaagaac tcctctcagt
    37141 tctgaggaca cggtaatgat tgatgcgacg gaagtacaaa tcaatcgccc taaaaaaaga
    37201 attagcgaat gattctggta aaaaaaatgc cacgctatga aggctcaagc gattgtcaca
    37261 agtcaaggga gaattgtttc tttggatatc
//
LOCUS       DAVHSH010000013        36784 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000013 DAVHSH010000000
VERSION     DAVHSH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.013"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            88..225
                     /locus_tag="VVR08_000802"
     CDS             88..225
                     /locus_tag="VVR08_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6074750.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     K"
     gene            232..735
                     /locus_tag="VVR08_000803"
     CDS             232..735
                     /locus_tag="VVR08_000803"
                     /inference="COORDINATES: protein motif:HMM:NF018653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6074751.1"
                     /translation="MSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVK
                     KGIGLIERVRLGLGKPNIIYVKDFMNIFQVKENDLQKSKNLTSEVKDFNLRSKENELQ
                     EVKNLDSNYIENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIR
                     LPAKLES"
     gene            complement(724..1529)
                     /locus_tag="VVR08_000804"
                     /pseudo
     CDS             complement(724..1529)
                     /locus_tag="VVR08_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1524..1778
                     /locus_tag="VVR08_000805"
     CDS             1524..1778
                     /locus_tag="VVR08_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6074752.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            2023..3357
                     /gene="trmFO"
                     /locus_tag="VVR08_000806"
     CDS             2023..3357
                     /gene="trmFO"
                     /locus_tag="VVR08_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU6074753.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            3441..4178
                     /locus_tag="VVR08_000807"
     CDS             3441..4178
                     /locus_tag="VVR08_000807"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU6074754.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            4187..4744
                     /gene="frr"
                     /locus_tag="VVR08_000808"
     CDS             4187..4744
                     /gene="frr"
                     /locus_tag="VVR08_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU6074755.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            4804..5658
                     /gene="cvfB"
                     /locus_tag="VVR08_000809"
     CDS             4804..5658
                     /gene="cvfB"
                     /locus_tag="VVR08_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU6074756.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            5667..5882
                     /locus_tag="VVR08_000810"
     CDS             5667..5882
                     /locus_tag="VVR08_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU6074757.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            5968..6936
                     /locus_tag="VVR08_000811"
     CDS             5968..6936
                     /locus_tag="VVR08_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU6074758.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(6914..7093)
                     /locus_tag="VVR08_000812"
     CDS             complement(6914..7093)
                     /locus_tag="VVR08_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074759.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            7129..7629
                     /locus_tag="VVR08_000813"
     CDS             7129..7629
                     /locus_tag="VVR08_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074760.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGFDLVAVMDFVYAYPDEETVFIGLFMVDPAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            7632..7891
                     /locus_tag="VVR08_000814"
                     /pseudo
     CDS             7632..7891
                     /locus_tag="VVR08_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(8258..8584)
                     /locus_tag="VVR08_000815"
     CDS             complement(8258..8584)
                     /locus_tag="VVR08_000815"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074761.1"
                     /translation="MVDIAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(8530..8943)
                     /locus_tag="VVR08_000816"
     CDS             complement(8530..8943)
                     /locus_tag="VVR08_000816"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU6074762.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(8944..9369)
                     /locus_tag="VVR08_000817"
     CDS             complement(8944..9369)
                     /locus_tag="VVR08_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU6074763.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            9546..10115
                     /locus_tag="VVR08_000818"
     CDS             9546..10115
                     /locus_tag="VVR08_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074764.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVILDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            10183..10833
                     /locus_tag="VVR08_000819"
     CDS             10183..10833
                     /locus_tag="VVR08_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEU6074765.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            10817..13057
                     /locus_tag="VVR08_000820"
     CDS             10817..13057
                     /locus_tag="VVR08_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU6074766.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GYLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLWDITGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLEVDVLKAGQHGSKKSS
                     SSAFLEKLKPELTLISVGKNNRTKLPHQETLTRLEGINSQVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            13199..13423
                     /locus_tag="VVR08_000821"
     CDS             13199..13423
                     /locus_tag="VVR08_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074767.1"
                     /translation="MIICLFQSSVSAVTATKSYKYDWNTVLEYSTNYHDHQYAWIPEW
                     SRYDSYSEYKVGGGWNYARYEVINYYTGGY"
     gene            13455..14042
                     /locus_tag="VVR08_000822"
     CDS             13455..14042
                     /locus_tag="VVR08_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074768.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            14046..15227
                     /locus_tag="VVR08_000823"
     CDS             14046..15227
                     /locus_tag="VVR08_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074769.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIVANERAINENEAKLSQMSDTSSEEYQFAKSNLELQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIIWILEAIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAMSS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVKQEVTIGKMQDVLFPS
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    15387..15518
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            15534..16064
                     /gene="infC"
                     /locus_tag="VVR08_000824"
     CDS             15534..16064
                     /gene="infC"
                     /locus_tag="VVR08_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU6074770.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            16097..16297
                     /gene="rpmI"
                     /locus_tag="VVR08_000825"
     CDS             16097..16297
                     /gene="rpmI"
                     /locus_tag="VVR08_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU6074771.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            16349..16708
                     /gene="rplT"
                     /locus_tag="VVR08_000826"
     CDS             16349..16708
                     /gene="rplT"
                     /locus_tag="VVR08_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU6074772.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            16766..17146
                     /locus_tag="VVR08_000827"
     CDS             16766..17146
                     /locus_tag="VVR08_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6074773.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            17396..18196
                     /locus_tag="VVR08_000828"
     CDS             17396..18196
                     /locus_tag="VVR08_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU6074774.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            18207..19145
                     /locus_tag="VVR08_000829"
     CDS             18207..19145
                     /locus_tag="VVR08_000829"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU6074775.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPVIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            19187..21220
                     /locus_tag="VVR08_000830"
     CDS             19187..21220
                     /locus_tag="VVR08_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU6074776.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(21281..22936)
                     /gene="pavA"
                     /locus_tag="VVR08_000831"
     CDS             complement(21281..22936)
                     /gene="pavA"
                     /locus_tag="VVR08_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU6074777.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            23041..23538
                     /gene="ybeY"
                     /locus_tag="VVR08_000832"
     CDS             23041..23538
                     /gene="ybeY"
                     /locus_tag="VVR08_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU6074778.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            23519..23914
                     /locus_tag="VVR08_000833"
     CDS             23519..23914
                     /locus_tag="VVR08_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU6074779.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            23931..24830
                     /gene="era"
                     /locus_tag="VVR08_000834"
     CDS             23931..24830
                     /gene="era"
                     /locus_tag="VVR08_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU6074780.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            24879..25703
                     /gene="mutM"
                     /locus_tag="VVR08_000835"
     CDS             24879..25703
                     /gene="mutM"
                     /locus_tag="VVR08_000835"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU6074781.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            25703..26308
                     /locus_tag="VVR08_000836"
     CDS             25703..26308
                     /locus_tag="VVR08_000836"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU6074782.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            26295..27494
                     /locus_tag="VVR08_000837"
     CDS             26295..27494
                     /locus_tag="VVR08_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEU6074783.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            27494..27643
                     /gene="rpmG"
                     /locus_tag="VVR08_000838"
     CDS             27494..27643
                     /gene="rpmG"
                     /locus_tag="VVR08_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6074784.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            27683..27916
                     /gene="secG"
                     /locus_tag="VVR08_000839"
     CDS             27683..27916
                     /gene="secG"
                     /locus_tag="VVR08_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU6074785.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            28018..30372
                     /gene="rnr"
                     /locus_tag="VVR08_000840"
     CDS             28018..30372
                     /gene="rnr"
                     /locus_tag="VVR08_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU6074786.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            30335..30802
                     /gene="smpB"
                     /locus_tag="VVR08_000841"
     CDS             30335..30802
                     /gene="smpB"
                     /locus_tag="VVR08_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU6074787.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            30818..31678
                     /gene="tehB"
                     /locus_tag="VVR08_000842"
     CDS             30818..31678
                     /gene="tehB"
                     /locus_tag="VVR08_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU6074788.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            31751..32704
                     /gene="coiA"
                     /locus_tag="VVR08_000843"
     CDS             31751..32704
                     /gene="coiA"
                     /locus_tag="VVR08_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU6074789.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKFLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            32723..34525
                     /gene="pepF"
                     /locus_tag="VVR08_000844"
     CDS             32723..34525
                     /gene="pepF"
                     /locus_tag="VVR08_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6074790.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVVQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREKELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            34527..35240
                     /locus_tag="VVR08_000845"
     CDS             34527..35240
                     /locus_tag="VVR08_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU6074791.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            35307..36248
                     /gene="prsA"
                     /locus_tag="VVR08_000846"
     CDS             35307..36248
                     /gene="prsA"
                     /locus_tag="VVR08_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU6074792.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(36365..36706)
                     /locus_tag="VVR08_000847"
                     /pseudo
     CDS             complement(36365..36706)
                     /locus_tag="VVR08_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        11103 a         6822 c         8237 g        10622 t
ORIGIN      
        1 aatttcataa aaatggttac caaaggcgat agaagaaaaa ctatcgtctt tttctttgca
       61 aatttttaag aagggaggtg atcttgcatg gactttgaat atttttataa cagagaagcg
      121 gaaagattta acttcttaaa agtaccggag atattagttg atagagaaga atttcggggc
      181 ttatcagcag aagcaattat cctttattcc atacttctta aatagacagg aatgtcattt
      241 aagaataact ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt
      301 atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta
      361 aaaaaaggaa taggactgat cgaaagagta aggcttggac ttggtaagcc gaacatcatt
      421 tatgttaaag actttatgaa tatatttcag gtaaaagaaa atgacttaca gaagtcaaaa
      481 aacttaactt cagaagtaaa agattttaac ctcagaagta aagaaaatga acttcaagag
      541 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
      601 tatagttttg gtgaaaacgg acttggaaca tttcaaaatg tgtttttagc tgctgaagat
      661 atatcggatt tacaaatcat aatgaactca cagcttgaga attacattag acttcctgca
      721 aaactagaat cctagttcat gattgataat accagcactc aaattcattc gtaatccgaa
      781 gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta ctttggcaaa
      841 gatattctca accttgcttc tctccttaga tagcgcatga ttacaggctt tatcttcaac
      901 tgttagcggc ttgagtttgc tggatttacg tggagtttgt acttgaggat atatcttcat
      961 gagcccttga taaccactgt cagccaagat ttttccagct tgtccgatat ttctgcgact
     1021 cattttgaac aacttcatat cgtggcaata gttcacagtg atatccaaag aaacaattct
     1081 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaata
     1141 attggctagt tgattttttt aggacgattt atttttacct ctgttgcatc cacaatcacc
     1201 gtatcctcag cactaagatg agtttttgaa atcgtaacac cactttgaac aagagttact
     1261 tcaacccatt ggctccgacg gattaagttg ctttcgtgaa taccaagatc agccgcaatt
     1321 tcttcataag tgcggtcttc tcacacatat tgaagagtgg ccataagaag gtcttctagg
     1381 cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt ttttaataca
     1441 gctaacatct cttcaaaagt ggtacgctga acaccaacaa gacgcttaaa tcgtgcatca
     1501 gttagttgtt tacttgcttc atcattcata gaactactat accatatttt gtttcgcagg
     1561 aagtctattg gaaagtaaga aatattgaag ctgaggctat tagaagaaat tgtgagcgtg
     1621 gtgctatttt ttcaggtaaa ataaaatatc acgaagattc acagtttaaa ggagatcact
     1681 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
     1741 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
     1801 aatactcact atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
     1861 tttttttgtt atactagtag aagaaaaaat agaaagattt gtgggagtga aaaagtcctg
     1921 tggacttttt cagcctgagc caagaaactc gaaagcttgt aagtctgatt ggctttttca
     1981 atgtgaatct taacttcaca ctcccaaaga ggtattagtg tcgtgtctca atcttatatc
     2041 aatgttatcg gtgctggttt ggcaggttct gaagcagctt accaaatcgc agagcgtggt
     2101 attccagtta aactatatga aatgcgtggt gtcaagtcta caccccagca taaaacagac
     2161 aattttgctg agttggtttg ttccaattct ttgcgtgggg atgctttgac aaatgcagtt
     2221 ggtcttctca aggaagaaat gcgtcgcttg ggttctgtta tcttggaatc tgctgaggct
     2281 acacgtgttc ctgccggtgg agcccttgcg gtggatcgtg atggtttctc tcaaatggtg
     2341 accgaaaaag tggtcaacca ccccttgatt gaagtggtac gtgatgaaat tacagaattg
     2401 ccaacagatg ttattacagt tgtggcgact ggtcccttga ctagcgatgc cctggctgaa
     2461 aagattcatg cccttaataa tggcgatggc ttctatttct acgatgcagc agcgcctatt
     2521 atcgatgtca acactatcga tatgagtaag gtctatctca aatctcgtta tgataaggga
     2581 gaagcagcct atctcaatgc tccaatgacc aagcaagagt ttatggattt ccatgaagcc
     2641 ttggtcaatg cggaagaagc accgctcaat tcttttgaaa aagaaaagta ctttgaagga
     2701 tgtatgccaa tcgaagttat ggccaaacgt ggcattaaaa ctatgcttta tggccctatg
     2761 aagccagtcg gtcttgagta tccggacgac tacacaggac ctcgtgatgg agaatttaaa
     2821 acaccttatg cggttgtgca acttcgtcag gataatgcag ctggtagcct atacaatatt
     2881 gttggtttcc agacccacct caaatgggga gaacaaaagc gtgtcttcca aatgattccg
     2941 ggtcttgaaa atgcggagtt tgtccgttat ggtgtcatgc atcgcaattc ttacatggat
     3001 tcaccaaatc ttcttgagca gacttaccgt tccaagaaac aaccaaatct cttctttgct
     3061 ggtcagatga cgggggtgga aggctatgtt gagtcggcgg cttcgggctt agttgcggga
     3121 attaacgcag ctcgtctctt caaggaagaa agcgaggtta ttttccccga gacgacagcg
     3181 attggaagct tagctcatta cattacccat gccgacagca aacatttcca accaatgaat
     3241 gtcaattttg ggatcatcaa ggagttggaa ggcgagcgta tccgtgataa gaaggctcgt
     3301 tatgaaaaaa ttgcagagcg tgcccttgcc gacttagagg aatttttgac tgtctaattt
     3361 ttttgaaaga attgttcatg atactataaa aatcttagaa attgtgataa aataggtagg
     3421 atgaaagaag gagagtgaaa atggcgaatc ccaagtataa acgtatttta atcaagttat
     3481 caggtgaagc ccttgccggt gaacgtggcg tagggattga tatccaaaca gttcaaacaa
     3541 tcgcaaaaga gattcaagaa gttcatagct taggtatcga aattgccctt gttatcggtg
     3601 gaggaaatct ctggcgtgga gaacctgcag cagaagcagg tatggaccgt gttcaggcag
     3661 attacactgg aatgcttggg actgttatga atgctcttgt gatggcagat tcattgcaac
     3721 aagttggggt tgatacgcgt gtacaaacag ctattgctat gcaacaagtg gcagagcctt
     3781 atgtccgtgg acgtgccctt cgtcaccttg aaaaaggccg tatcgttatc tttggtgctg
     3841 gaattggttc accatacttc tcgacagata caacagcggc ccttcgtgca gctgaaatcg
     3901 aagcagatgc catcctcatg gctaaaaatg gcgtcgatgg tgtgtacaat gccgatccta
     3961 agaaggacaa gacagccgtt aagtttgaag aattgaccca ccgtgatgtt atcaacaaag
     4021 gtcttcgtat catggactca acagcctcaa ccctctcaat ggacaacgac attgacttgg
     4081 ttgtcttcaa catgaaccaa tcaggcaaca tcaaacgtgt cgtatttggt gaaaatatcg
     4141 gaacaacagt ttcaaataat atcgaagaaa aggaataaga aagaatatgg ctaacgtaat
     4201 tattgaaaaa gctaaagaga gaatgaccca gtctcaccaa tcacttgctc gtgaatttgg
     4261 tggtatccgt gctggtcgtg ccaatgcaag cttgcttgac cgtgtacatg tagaatacta
     4321 tggagtcgaa actcctctta accaaatcgc ttcaattacg attccagaag cgcgtgtttt
     4381 gttggtaaca ccatttgaca agtcttcatt gaaagacatc gaacgtgcct tgaacgcttc
     4441 tgatcttggt atcacaccgg ctaatgacgg ttctgtgatt cgcttggtta tcccagctct
     4501 tacagaagaa actcgtcgtg accttgctaa agaagtgaag aaggtcggcg aaaatgctaa
     4561 agtggctgtc cgcaatatcc gtcgcgatgc tatggacgaa gctaagaaac aagaaaaagc
     4621 aaaagaaatc actgaagacg aattgaagac tcttgaaaaa gatattcaaa aagtaacaga
     4681 cgatgctgtt aaacacatcg acgacatgac tgctaacaaa gagaaagaac ttttggaagt
     4741 ctaaaaataa acagaaaaac tcagttggca ttgctggctg agttttattc gaaagaagga
     4801 aatatgaata caaatcttgc aagttttatc gttggactga tcatcgatga aaatgaccgt
     4861 ttttactttg tgcaaaagga tggtcaaacc tatgctcttg ctaaggaaga gggccaacat
     4921 acagtagggg atacggtcaa aggttttgca tacacggata tgaagcaaaa actccgcctg
     4981 acaaccttag aagtgactgc cactcaggac caatttggtt ggggacgtgt cacagaggtt
     5041 cgtaaggact tgggtgtctt tgtggataca ggccttcctg acaaggaaat cgttgtgtca
     5101 ctcgatattc tccctgagct caaggaactc tggcctaaga agggcgacca actctacatc
     5161 cgtcttgaag tggataagaa agaccgtatc tggggcctct tggcttatca agaagacttc
     5221 caacgtcttg ctcgtcctgc ttacaacaac atgcagaacc aaaactggcc agccattgtt
     5281 taccgtctca agctatcagg aacttttgtt tacctaccag aaaataatat gcttggtttt
     5341 attcatccta gcgagcgtta cgcagagcca cgtttggggc aagtattaga tgcgcgcgtt
     5401 attggtttcc gtgaagtgga ccgcactttg aacctctccc tcaaaccacg ctcctttgaa
     5461 atgttggaaa acgatgctca gatgattttg acttatttgg aaagcaatgg cggtttcatg
     5521 accttaaatg acaagtcatc tccagacgac atcaaggcaa cctttggcat ttctaaaggt
     5581 cagttcaaga aagctttagg tggtcttatg aaggctggta aaatcaagca ggaccagttt
     5641 ggtacagagt tgatttaggg aggcttatga gaaaatcatt ttacacttgg ctcatgaccg
     5701 agcgcaatcc taaaagtaac agtcccaaag caattttggc agacctcgct tttgaagagg
     5761 cagcttttcc aaaacataca gatgattttg atgaggtcag tcgctttttg gaggagcatg
     5821 ccagtttctc ttttaaccta ggagattttg acagcatttg gcaggaatat ctagaacact
     5881 agcatttatt cattgggttt gggctagtaa tttctccatc cctctgctat aataaaaaga
     5941 aataaaagga ttagagaggt tctttatttg aaggaacatt caatagacat tcaactgagt
     6001 catccagatg acctgtttca tctttttggt tccaatgaac gccatcttcg tttgatggaa
     6061 gaagagcttg atgttgtgat tcatgctcgt acggagattg tccaggtttt gggagaagag
     6121 tctgcctgtg aggaagcccg tcaagttatt caggctttga tggtcttggt aaatcgtggg
     6181 atgaccgttg gtacgccaga tgtagtcact gcgattagca tggtcaaaaa tgatgaaatt
     6241 gacaagtttg tcgcccttta cgaagaagaa attatcaaag ataatactgg gaaacctatc
     6301 cgtgtcaaaa ccctagggca aaagctttat gtggacagtg tcaaacagca tgatgtgacc
     6361 tttggaattg ggccagcagg tacagggaag accttccttg cagtgacctt ggcagtgact
     6421 gcccttaaac gtgggcaagt caagcgaatt atcctaactc gtccagcggt ggaagcggga
     6481 gagagtcttg gatttcttcc gggtgatctt aaggagaagg tggatcctta ccttcgtcct
     6541 gtttacgatg ccttgtatca aattcttggg aaagaccaaa cgactcgtct catggagcgt
     6601 gaaattatcg aaattgcgcc ccttgcctat atgcgtggcc ggaccttgga tgatgccttt
     6661 gtcattctcg atgaggcgca aaacacgacc atcatgcaga tgaagatgtt cttgacgcgt
     6721 ttaggttttc attctaagat gattgtcaat ggagatatca gtcagattga cctgccacgt
     6781 aatgtcaagt ccggtttgat tgatgctcaa gagaaactca agaacatcca tcagattgac
     6841 tttgttcatt tttcagccaa ggatgtggtt cgccatcctg ttgtcgctca gattatccga
     6901 gcctatgaat attctactga agttgcacac gactgatttt gaggaagttc gcctgcaaaa
     6961 gaatatactt ttgagagagg aaaatccagt tgtataggct aaaggtttta tccaaaggtt
     7021 tgagacaacg attaggcacg atggaaagaa cttttatgtg actgatgacg atcagtgcat
     7081 cttcctgtgt cataatcaca gggcacaaga aagtaggaat ttgaaaagat gattgaccaa
     7141 ctatctaagt attacagttg taggatacta actgaaaagg atattccaag tattttatct
     7201 ttatatgaaa gtaatcctct gtattttcag cattgtccac cagagccaaa ttttgcaact
     7261 gtaaaagagg acatgctttg tctacctgaa ggtaaagcta aggctgataa gttttttgtt
     7321 ggattttgga atggatttga ccttgtggct gttatggatt ttgtctatgc atatcctgat
     7381 gaggagactg tttttattgg tttgtttatg gttgatccag cctatcagag gaaagggatt
     7441 ggtagtcata ttgtgacaga agcactagct tattttgcta agaactttcg aaaggcacgt
     7501 ttggcttatg ttaagggaaa tccgcaatct cagcattttt gggaaaagca gggctttaaa
     7561 tcaattggat gcgaggttaa gcaagaactc tatacggttg ttatcgttga acagagccta
     7621 gaagattaga aatggcatca agtaagaact atttggaatt tgttttggaa caattatcag
     7681 gattagatga tgtgacttac cgttccatga tgggggagta tattctttac ttccgcggca
     7741 agattattgg cggcatttat gacgatcgct tttagttaaa cccgtgcaag cagtcttaga
     7801 taagattgac caatcttctt ttgagtttcc atacaaaggt gccaaagaaa tgatttgagt
     7861 ggaagaactt gataataaga tgtttctata agacctgatt ttagctatgt ataaccaact
     7921 gccaacgccc aaacctaaaa agaaaaagca agggtgaacg aagtaaaaaa gaagtctgct
     7981 aaggccctgt ctttgcacgg gtaaaatttt atatataaaa agaagctggg actaaagagc
     8041 tcagcttcct ttggtttata taattgtcat tacaagacga agtggttggg cgaaactctg
     8101 ttgactttat tcaatttaga gtttcttatg cacaattgag tctggaacga aagtctccag
     8161 ttgcaaagta tacagtacaa taaaccaacg atgtaatagc tgatgacaca aagcacagtg
     8221 ggtaggactt gcgaagtcac ccttttcttt tcaaaattta tactaaatca ttgatatcag
     8281 tgtagtcacg attaagtcct tgagcaactg gtaggctagt caagtaacct tgataagtgg
     8341 tcacaccttg acgcaagcct tcatcttcag agattgcttg tgcgaatcct ttgccagcca
     8401 aagcttcgat ataaggaaga gtgacattgg ttagggcgat ggttgaagtg cgggcaaccg
     8461 caccagggat attggcaacg gcatagtgga gaacaccgtg tttttcatag acgggttcat
     8521 cgtgcgttgt cacacggtca gctgtttcga taaggccacc ttggtcaaca gcaatgtcaa
     8581 cgatacagag cctggacgca tttgtttgac catctcatct gtcaccaatt ccggtgcttt
     8641 tgcaccaggg atgagaatgg ctccaatcac cacatcagca tctctcacac ttgcttcaat
     8701 gttgaatgaa ttagacataa gagtttgaat ttgacttcca aagacttctt ctagaactga
     8761 gagacgcttg gcactaatat ctaaaatagt cacttgagca ccaagaccaa gggcgatgcg
     8821 ggcagcatgt gtaccgacga caccatcacc gatgatagtt acttttcctt ttggaacacc
     8881 tggtacacca ccaagtagaa caccagagcc accagcttgc ttagtaagga agtgagctcc
     8941 gatttaaaca gccatacgac ctgcaacctc actcatagga acgaggagcg gtagttgtcc
     9001 ttgattgtca cgaacagttt cataggcaat tcctgttgtt tttgctgcta acatagcatc
     9061 tgctaattct ggagcagcgg ccatgtgcaa gtaggtgaag agaagaagat cgtcgcgcaa
     9121 gtaaccgtat tcagaactta aaggttcttt tactttcaca accaactctg ctgcccaagc
     9181 ttcaccagca gtagcgacaa tctcagctcc ttgcttttga tagtcagcat cagtaaagcc
     9241 agaaccgaga ccagcatttg tttcgataag gacacgatga ccacgactaa ctaagctatg
     9301 aacacctgca ggtgtgaggg cgacacggtt ttcgttattt ttaatttctt ttgggattcc
     9361 gattaacatt gagataacct acctttcaat tgacggtctt gttttggttg tcacattcca
     9421 gttcataaat caaaaatgtg acggtttcat tgtatatgaa accgcttcaa aaatcaagaa
     9481 aaacttgtca tccaaatttt tttatgctag actagtgaaa atcaagctct aatggaggga
     9541 aaagtatgga atcaatattt gtgaaatttg cccagtatcc gtctatagaa acggagcgtt
     9601 tattgcttag acctgtaatt ttggatgatg cggaagcaat gtttgactat gcctcggaca
     9661 agggtaatac acgttacact tttccaacca atcaaagctt ggaagaaacc aagaataaca
     9721 ttgctcagtt ctacttggct aatcccttgg gacgttgggg aatagaacta aaaagcaatg
     9781 gtcagtttat tggaaccatt gacttgcaca agattgattc tgttcttaag aaggcagcta
     9841 ttggctacat tatcaataaa aagtattgga atcaaggatt aacgacagaa gccaatcgtg
     9901 ctgtgattga gctagctttt gagaagatag ggatgaataa gttgactgcc cttcacgata
     9961 aggctaatcc cgcgtcagga aaggtcatgg agaaatcagg catgcgtttt tcccatgcag
    10021 aaccatatgc ttgtatggac cagcatgaaa aagatcgaat cgttacaaga gttcattatg
    10081 tcttgaccaa ggaagactat tttgcaaata aataagcagt tgaaaagaaa tttttcgact
    10141 gttttttctt cctcttacga ataatctaag agaggagaaa atatggaagc aattatcgag
    10201 aaaatcaaag agtataaaat catcgtcatc tgtactggtc tgggcttgct tgtaggagga
    10261 tttttcctgc taaagccagc tccacaaaca cctgtcaaag agacgaattt gcaggctgaa
    10321 gttgcagctg tttccaagga ctcatcgacc ggaaaggaag tgaacaagga agagaaggaa
    10381 gaaccagttg aacaagatct aatcacagta gatgtcaaag gtgctgtcaa atcgccaggg
    10441 atttatgact tgcctgtagg tagtcgagtc aatgatgctg ttcagaaggc tggtggcttg
    10501 acagagcaag cagacagcaa gtcgctcaat ctagctcaga aagttagtga tgaggctctg
    10561 gtttacgttc ctactaaggg agaagaagca gttagtcaac agactggttc ggggacagct
    10621 tcttcaacaa gcaaggaaaa gaaggtcaat ctcaacaagg ccagtctgga agaactcaag
    10681 caggtcaagg gactgggagg aaaacgagct caggacatta ttgaccatcg tgaggcaaat
    10741 ggcaagttca agtcagtaga cgagctcaag aaggtctctg gcattggtgc caagaccata
    10801 gaaaaactta aagactatgt tacagtggat taagaatttc tctattcccc taatttacct
    10861 gagttttctg ttactatggc tttactacgc cattttctca gtatcctatt ttgctttgtt
    10921 gggttttgtt tttctgctag tctgcctctt tatccaattt ccttggaaat cagcaggtaa
    10981 agttctagtg atttgtggag tctttggctt ctggtttctg tttcaaactt ggcaacagag
    11041 tcaagtgagt caaaatttgg tggattctgt tgaaagggta cggattttac cagacactat
    11101 taaggtcaac ggtgacagtc tgtcctttcg tggtaagtct gatggtcgtg ctttccaagt
    11161 ctattataaa ctccagtccg aggaggagaa agaagccttt caagctttaa ctgaccttca
    11221 tgagatagga ctagaaggga agctttcgga gccagaaggg cagagaaatt ttggtggctt
    11281 tgactaccaa ggctatctga agactcaggg aatttaccag acactcaata ttaaaagaat
    11341 ccagtcactc caaaaggttg gtagttggga tataggtgaa aacctgtcca gtttacgtcg
    11401 aaaggctgtg gtttggatta agatgcactt cccagaccct atgcgcaatt acatgacagg
    11461 acttttgctg ggatatctgg acaccgactt tgaggagatg aatgagcttt attccagtct
    11521 aggaattatc cacctctttg ccctatctgg catgcaggta ggttttttca tgaatggatt
    11581 taagaaactt ctcttgcaat tgggcttgac ccaagaaaag ttgaaatggc taacttatcc
    11641 cttttccctt atctatgcgg gactaactgg attttcagca tcggttattc gcagtctctt
    11701 gcaaaagcta ctggctcaac atggggttaa gggcttggat aattttgcct tgacggtgct
    11761 tgtcctcttt attgtcatgc caaacttttt cttgacagca ggaggagtct tgtcctgcgc
    11821 ttatgctttt atcctgacca tgaccagcaa agaaggggag gggctcaagg ctgttgctag
    11881 tgaaagtcta gtcatctcct tgggcatatt gcccattcta tccttctatt ttgcggaatt
    11941 tcaaccttgg tctatccttt tgacctttgt cttttccttt ctatttgact tgaccttctt
    12001 accgctcttg tctattttat ttgtcctttc ctttctctat ccagtcattc agctgaactt
    12061 tatctttgaa tggttggagg gcattattcg cttggtgtca caggtgacaa gtagacctct
    12121 ggtctttgga caacccaatg catggttttt aatcctattg ttaatttcct tggctttggt
    12181 ctatgatttg agaaaaaaca ttaaaaagct aacggtattg tgcttattga ttacagggct
    12241 ctttctcctg accaagcatc cactggaaaa tgaaatcacc atgctggatg tggggcaagg
    12301 agaaagtatt ttcctatggg atataactgg gaaaaccatt ctcatagatg tcggtggcaa
    12361 ggcagaatct tataagaaaa tcgaaaaatg gcaagaaaag atgacgacca gcaatgccca
    12421 gcgaaccttg attccctatc tcaaaagtcg aggagtagct aagattgacc agctaatttt
    12481 gactaacacg gacaaggagc atgttggaga tttgtcagag gtgaccaagg ctttccatgt
    12541 aggggagatt ctagtatcaa aagacagtct gaaacagaag gaatttgtgg cagaactaca
    12601 ggcgactcaa acaaaggtgc gtagtatgac agtaggggag aacttgccca tttttggaag
    12661 tcagttagaa gttctatctc caaggaaaat gggagatgga ggacacgatg ataccctagt
    12721 tctgtatggg aaattcttgg ataagcaatt tctcttcacg ggaaatttgg aggagaaagg
    12781 agagaaggac ttgctgaagc actatcctga cctcgaggtg gatgtcttga aagctggcca
    12841 acatggctct aaaaaatcat caagttcagc ctttctagaa aaactcaaac cagagcttac
    12901 tcttatctca gttggaaaga ataatcgaac gaaattacca catcaagaaa ccttgactcg
    12961 actggaaggt atcaatagtc aagtttaccg aactgaccag caaggagcta tacgctttaa
    13021 ggggttggat agttggaaaa tcgaaagtgt tcgataggaa agataaatgt tgtagattag
    13081 tgaaataaac taaaaatttg ttgcataata atgataaaaa tggtataatg aaaacgtatt
    13141 caatgctgag gatataaaat cattaaaaat tagcaaaaat cgtttaatta gttagtttat
    13201 gattatttgt ctttttcagt ccagtgtatc tgctgtgaca gccactaaaa gttacaagta
    13261 tgattggaat acggttttgg aatatagtac caactatcac gaccatcagt atgcttggat
    13321 tccggaatgg tctcgttatg acagctattc tgagtataaa gttggcggag gctggaacta
    13381 cgctcgttat gaggtcataa actactatac tggaggttat taatccttaa agagtgagaa
    13441 aaggagggct ggatatgtta aatcttactc atgttacctt aaaaacgcga caagtcatct
    13501 tgcaagatgc ggattttacc tttaaaaagg gtaggattta tggccttctt gctatcaatg
    13561 gctcgggaaa gacgacacta ttccgagcta tgagcaagtt gcttcccctt agtagtggac
    13621 acatcgcagt tcctccttct ttgttttatt atgagagcgt tgaatggctg gatggaaact
    13681 taagtgggat ggactacctt cgtctcataa aaaacatctg gaagtcagac ctaaacttga
    13741 gagatgaaat cgcctactgg gaaatggctg actatatcag tcttcccatc cgcaagtatt
    13801 ccttagggat gaagcaacgc ttggtgattg ctatgtattt tctcagtcag gccaaatgct
    13861 ggctcatgga tgagattaca aatggcttag acgagtatta tcgacagaag ttttttgata
    13921 ggctagcaca aatcgataga caagaacagc tggttctttt aagttcccac tataaggaag
    13981 agttggttga tatctgcgat agagtagtaa ccattcatca ggggcagata gaagaggttt
    14041 agtttatgaa agatgttagt ctatttttat tgaaaaaagt tttcaaaagt cgtttaaact
    14101 ggattatctt acttttattt gcatctgtac tcggtgttac cttttattta aatagtcaga
    14161 ctgcaaactc acacagcttg gagagcaggt tggaaagtcg cattgtagcc aacgagagag
    14221 ccatcaatga aaatgaagcg aaactttccc aaatgtctga caccagctcg gaggaatacc
    14281 agtttgctaa aagtaattta gaattgcaaa aaaatctttt gaagcgaaag acagaaattc
    14341 tgactttatt aaaagaaggg cgctggaaag aggcctacta tctgcagtgg caagatgaag
    14401 agaagaatta tgaatttgta tcaaatgacc cgactgctag ctctggctta aaaatggggg
    14461 ttgaccgcga acggaagatt taccaagccc tgtatccctt gaacataaaa gcacatactt
    14521 tggagtttcc gacccacggg attgatcaga ttatctggat tttagaggct atcatcccaa
    14581 gcttgtttgt ggttgctatt atttttatgc taacacaact atttgcagaa agatatcaaa
    14641 atcatctgga cacagctcac ttatatcctg tttcaaaagt gacatttgca atgtcttctc
    14701 ttggagttgg agtgggctat gtaactgtgc tgtttatcgg aatctgtggc ttttcttttc
    14761 tagtgggaag tctgataagt ggttttggac agttagatta tccctacccg atttatagct
    14821 tagtgaaaca agaggtaact attggaaaga tgcaggatgt attatttcct agcttgctct
    14881 tagctttctt agcctttatc gtcattgtgg aagttgtgta tttgattgct tactttttca
    14941 agcaaaaaat gcctgtcctc tttctttcac tcattgggat tgttggctta ttgtttggca
    15001 tccaaaccat tcagcctctt caaaagattg cacatctgat tccctttact tacttgcgtt
    15061 cagtggagat tttatctgga agattaccta agcagattga taatgtcgat ctaaattgga
    15121 gcatggggat ggtcttactt ccttgcctga ttatcctttt gttagtgggg attctattta
    15181 tcgaaagatg gggaagttca cgtaaaaagg aagtttttaa agtttagttt tcctataggg
    15241 aagctaaaga aaaactaaca tagggagaga atcaacttgg ttctctcttt ttgattcgaa
    15301 aaccaaacca aaatataaac acaaactttt caaaaaataa ctttttatct tgacaagagc
    15361 tagaaaactt ggtatcatat aaaagttgag aaaagcagaa gtgagagctt ctcgccttgt
    15421 gacattaagt tgcctggccc tacggatgaa aagtttcgaa gaaacgctat cataacgtgc
    15481 gggcttgtat atttacgagt ccgctattgt ttttctctaa taaaacaaaa gaggtgaaaa
    15541 ccatagcaaa gcaagactta ttcatcaatg atgagattcg tgtacgtgaa gttcgcttga
    15601 ttggtcttga gggagaacag ctaggcatca agccactcag tgaagcgcaa gctttggctg
    15661 ataacgctaa tgttgaccta gtattgattc aaccccaagc caaaccgcct gttgcaaaaa
    15721 ttatggacta cggtaagttc aaatttgagt accagaagaa gcaaaaagaa caacgtaaaa
    15781 aacaaagcgt tgttactgtg aaagaagttc gtctaagtcc aacaattgac aagggtgact
    15841 ttgatacaaa acttcgcaat gcacgtaagt tccttgaaaa aggaaataaa gttaaggtat
    15901 ctattcgctt taagggtcgt atgattaccc ataaagagat tggtgcaaaa gttttagccg
    15961 agtttgctga agcaactcaa gatattgcca tcatcgaaca acgtgctaaa atggatggac
    16021 gtcaaatgtt catgcaattg gcgccagcga ctgacaaaaa ataattgtca gaaagttaaa
    16081 taaaggagaa aaaatcatgc caaaacaaaa aacacaccgc gcatcagcta aacgtttcaa
    16141 acgtacaggt tctggtggac ttaaacgttt ccgtgcttac acttctcacc gtttccacgg
    16201 aaaaactaag aaacaacgtc gtcatcttcg taaagcatct atggtgcatt caggagatta
    16261 caaacgtatc aaagcaatgc ttactcgctt gaaataatag cttgactgta agtaaacaat
    16321 tctaggaaat atttggagga aataaaacat ggcacgtgtt aaaggtggcg ttgtatcacg
    16381 caaacgtcgt aaacgtattc ttaaattagc aaaaggttac tatggagcta aacacatctt
    16441 gttccgtact gcaaaagaac aagtaatgaa ctcttactac tatgcatacc gtgaccgtcg
    16501 tcagaaaaaa cgtgacttcc gcaaattgtg gattactcgt atcaatgcgg cagctcgtat
    16561 gaacggactt tcatactcac aattgatgca tggtttgaaa ttggctgaga ttgaagttaa
    16621 ccgtaaaatg cttgctgact tggctgttaa cgatgcagta gctttcacag ctcttgcaga
    16681 tgcagctaaa gcaaaacttg gtaaataaca actgatgaga ctggaacagg attgtccagt
    16741 ctttttaaaa ataaaggaga aagatatggc ttcaaaaatg ctacacactt gcttacgagt
    16801 agaaaatctt gaaaaatcaa tcgcatttta tcaagatgct tttggtttta aagaattgcg
    16861 tcgcagagat tttccagacc atgccttcac gattgtctat ctaggtcttg agggtgatga
    16921 ttatgagttg gagttgactt ataactacga tcacggtccg tatgtggttg gtgatgggtt
    16981 tgcccatatc gccctcagta cacctgatct tgaggcactt catcaagaac acagtgcaaa
    17041 aggctatgaa gtgactgagc caaatggtct accaggaact acaccaaact attactttgt
    17101 taaagaccct gatggatata aggtcgaagt cattcgtgaa aaataatttc gtgcaagtta
    17161 agtagaatat tcgttttcta cttgactttt tttagctgaa agagtatact aataaaaatt
    17221 caacctttaa ggggagtcca gagagactca caaggtgtca gataaaagaa tagtgcaatt
    17281 ttctagagga gaccttttga gtgtgctctc ttgtgttgta cgattttaac tgaggccttg
    17341 cactagcaag gtcttttctt tatctggtcc ccttaaaatt taaggaggaa aagttatgaa
    17401 tctcacatgt aagaagcgtt tgggtgtcat tcggttggaa accatgaagg tggttgcaca
    17461 agaggaaatc gcgccagcaa tctttgaatt agtcctagaa ggagaaatgg ttgaagccat
    17521 gcgagcaggc caatttcttc atctgcgtgt accagacgat gcccatctct tacgtcgtcc
    17581 tatttcaatt tcgtctattg acaaggcaaa caagcagtgt cacctcattt atcggattga
    17641 gggagctggg actgcaattt tttcaacctt aagtcaggga gacactcttg atgtgatggg
    17701 gcctcaggga aatggttttg acttgtctga ccttgatgag cagaatcagg ttctccttgt
    17761 tggtggtggg attggtgttc cacccttgct tgaggtggcc aaggaattgc atgaacgtgg
    17821 agtgaaagta gtgacagtcc taggttttgc taataaggat gctgttattt tgaaaacgga
    17881 attggctcag tatggtcagg tctttgtaac gacagatgat ggttcttatg gcatcaaggg
    17941 aaatgtttcc gttgttatca atgatttaga tagtcagttt gatgctgttt actcgtgtgg
    18001 ggctccagga atgatgaagt atatcaatca aacctttgat gatcacccaa gagcctattt
    18061 atctctggaa tctcgtatgg cttgtgggat gggagcttgc tatgcctgtg ttctaaaagt
    18121 accagaaagc gagacggtca gccaacgcgt ctgtgaagat ggtcctgttt tccgcacagg
    18181 aacagttgta ttataaggag aaaattatga ctacaaatcg attacaagtg tctctacctg
    18241 gtttggattt gaaaaatccg attattccag catcaggctg ttttggcttt ggacaagagt
    18301 atgccaagta ctatgattta gaccttttag gttctattat gatcaaggcg acaacccttg
    18361 aaccacgttt tgggaatcca actccaagag tggcagagac gcctgctggt atgctcaatg
    18421 caattggctt gcaaaatcct ggtttagagg ttgttttggc tgaaaagcta ccttggctgg
    18481 aaagagaata tccaaatctt cctattattg ccaatgtagc tggtttttca aaacaagagt
    18541 atgcagctgt ttctcatggg atttccaagg caactaatgt aaaagctatc gagctcaata
    18601 tttcttgtcc caatgttgac cactgtaatc atggactttt gattggtcaa gatccagatt
    18661 tggcttatga tgtggtgaaa gcagctgtgg aagcctcaga agtgccagtt tatgtcaaat
    18721 taaccccgag tgtgaccgat atcgttactg tcgcaaaagc tgcagaagat gcgggagcaa
    18781 gtggcttgac catgatcaat actctggttg gaatgcgctt tgacctcaaa accagaaaac
    18841 caatcttggc caatggaaca ggtggaatgt caggtccagc agtctttcca gtagccctca
    18901 aactcatccg ccaagtagcc caaacaacag acctgcctat cattggaatg gggggagtgg
    18961 attcggctga agctgcccta gaaatgtatc tggctggggc atctgctatc ggagttggaa
    19021 cagctaactt taccaatcct tatgcctgtc ctgtcatcat cgaaaattta ccaaaagtca
    19081 tggataaata cggtattagc agtctggaag aactccgtca ggaagtaaaa gagtctctga
    19141 ggtaaactgc aatcaatctg ttcttgattt tttattagtt tgtaatatga atttaggaga
    19201 attttggtac aataaaataa ataagaacag aggaagaagg ttaatgaaga aagtaagatt
    19261 tattttttta gctctgctat ttttcttagc tagtccagag ggtgcaatgg ctagtgatgg
    19321 tacttggcaa ggaaaacagt atctgaaaga agatggcagt caagcagcga atgagtgggt
    19381 ttttgatact cattatcaat cttggttcta tataaaagca gatgctaact atgctgaaaa
    19441 tgaatggcta aagcaaggtg acgactattt ttacctcaaa tctggtggct atatggccaa
    19501 atcagaatgg gtagaagaca agggagcctt ttattatctt gaccaagatg gaaagatgaa
    19561 acgaaatgct tgggtaggaa cttcctatgt tggtgcaaca ggtgccaaag taatagaaga
    19621 ctgggtctat gattctcaat acgatgcttg gttttatatc aaagcagatg gacagcacgc
    19681 agagaaagaa tggctccaaa ttaaagggaa ggactattat ttcaaatccg gtggttatct
    19741 actgacaagt cagtggatta atcaagctta tgtgaatgct agtggtgcca aagtacagca
    19801 aggttggctt tttgacaaac aataccaatc ttggttttac atcaaagaaa atggaaacta
    19861 tgctgataaa gaatggattt tcgagaatgg tcactattat tatctaaaat ccggtggcta
    19921 catggcagcc aatgaatgga tttgggataa ggaatcttgg ttttacctca agtttgatgg
    19981 caaaatggct gaaaaagaat gggtctacga ttctcatagt caagcctggt actacttcaa
    20041 atccggtggt tacatgacag ccaatgaatg gatttgggat aaggaatctt ggttttatct
    20101 caaatctgat gggaaaatag ctgaaaaaga atgggtctac gattctcata gtcaagcttg
    20161 gtactacttc aaatccggtg gttacatgac agccaatgaa tggatttggg ataaggaatc
    20221 ttggttttac ctcaagtctg atggcaaaat ggctgaaaaa gaatgggtct acgattctca
    20281 tagtcaagcc tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga
    20341 tggttatcag cttggaagcg atggtaaatg gcttggagga aaagctacaa ataaaaatgc
    20401 tgcttactat caagtagtgc ctgtcacagc caatgtttat gattcagatg gtgaaaagct
    20461 ttcctatata tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa
    20521 gcgcttggct attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc
    20581 gctagatgct agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca
    20641 ctatgtggct cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg
    20701 caagaaatat tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt
    20761 ccttttcaaa gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt
    20821 tagtttgcta aacattaata atagcctttt ggagaacaag ggcgctactt ttaaggaagc
    20881 cgaagaacat taccatatca atgcccttta tctccttgcc catagtgccc tagaaagtaa
    20941 ctggggaaga agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga
    21001 tacgacccct tacctttctg ccaagacatt tgatgatgtg gataagggaa ttttaggtgc
    21061 aaccaagtgg attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc
    21121 ttctggtatg aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt
    21181 gatgatgaaa atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt
    21241 tgagtgaata gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg
    21301 caattttttt ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc
    21361 cgggttttcc accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca
    21421 gattcgacag gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg
    21481 catcagatgg gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat
    21541 ggaaccaaag ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt
    21601 ttcgtccgac atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc
    21661 gtttctggat tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac
    21721 ggatttcagc gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat
    21781 agagaatagt ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga
    21841 gtttctgata ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa
    21901 gcgcaatcat gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt
    21961 taggcacttg gtggaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt
    22021 tgtctgtcgc cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt
    22081 cattttcaac acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct
    22141 tatccttata gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat
    22201 ttgcaaaagg aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga
    22261 aaaaatttcg gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg
    22321 tatcgcgtcc cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt
    22381 gtaggatttc aaagagcttt tcatccttga tagtaaaagg attgagagat tttgtacttg
    22441 gcggagcgat ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaaaccga
    22501 cgtgtttgat aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt
    22561 gttttcccat aatttcaata atcaaggtag cctggatatg gtctccaatc tcgtttttat
    22621 tggaaactgt aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg
    22681 ccccctgcaa atactttctc aaaaccatga taaaggtaga aggttgagct ggattttcaa
    22741 aagtcgtttg ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat
    22801 ggctttggcg attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt
    22861 tctggatgcg accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa
    22921 atccgtcaaa tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag
    22981 gtagaataaa atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac
    23041 atgtatattg aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc
    23101 caagaaattt tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc
    23161 acttttgtga ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt
    23221 ccgacagatg tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag
    23281 gatttgcttg aaaatccaga attggcagag atgatgtctg agtttgatgc ctatattggg
    23341 gaattgttca tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt
    23401 gagcgtgaga tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac
    23461 tatactccgg aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat
    23521 ggactcacaa gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt
    23581 tgccatcaca gggattttta ctgctatcaa ggaagaacga aatatgcgaa aacatgcagt
    23641 gacggctcta gtggtcatcc ttgcaggttt tgtttttcag gtgtcacgaa tcgaatggct
    23701 ctttctccta ttgagtattt tcttggtagt agcctttgag attatcaact ctgctattga
    23761 aaatgtggtg gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga
    23821 tatggcggcc ggcgcggtat tagtggtttc tcttttcgca gccttaacag gcgcattgat
    23881 ttttctccca cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta
    23941 aatcaggctt tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc
    24001 acgttatggg gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa
    24061 tcatgggaat ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc
    24121 acaaacctaa aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg
    24181 aagtggacac cgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata
    24241 tgattatcga gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg
    24301 ataaggtcca tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact
    24361 ttaaggaaat tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata
    24421 ttttgagtga aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagacc
    24481 atccagaacg tttcttggtt tcagaaatgg ttcgcgagaa agtcttgcat ctaactcgtg
    24541 aagagattcc gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag
    24601 acaaggttca catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca
    24661 tcggtaaagg tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt gatatcgaac
    24721 tcatgctagg agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg
    24781 ataaaaagct agatttggct gactttggct ataatgaaag agaatactaa gtagaggtag
    24841 gctcatgcct gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg
    24901 aaaccgtttg tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa
    24961 ttcgctaccc caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc
    25021 agattatcga gtcaatggga cgtcgtggaa aatatttgct tttctgcctg acagacaagg
    25081 tcttgatttc ccatttgcgg atggagggca agtattttta ttatccagac caagtgcctg
    25141 aacgcaagca tgcccatgtt ttcttccggt ttgaagatgg gggcacgctt gtttatgagg
    25201 atgtacgcaa gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta
    25261 tttctaaaaa attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaag
    25321 ctgcccttgc caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag
    25381 ctggacttgg caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta
    25441 gaccttccca gactttgaca gcagaagaag cgactgccat tcatgaccag accattgctg
    25501 ttttgggcca ggctgttgaa aaaggtggct ccaccattcg gacttatacc aatgcctttg
    25561 gggaagatgg aagcatgcag gactttcatc aggtctatga taagactggt caagaatgtg
    25621 tacgctgtgg taccatcatt gagaaaattc aactaggcgg acgtggaacc cacttttgtc
    25681 caaactgtca aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc
    25741 aggtaagtca actgtgacaa attttctaag acagcaaggc tttcaagcag tggatgccga
    25801 cgcagtcgtc caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca
    25861 ctttgggcaa gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct
    25921 catcttttca aatcctgaag agcaaaaatg gtctaagcaa attcaagggg agattatccg
    25981 tgaggaactg gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga
    26041 tattccccta ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta
    26101 tgtggaccga gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga
    26161 agctgagtct cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca
    26221 ggttcttgat aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga
    26281 gggaggtagg caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg
    26341 gtaattttct gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg
    26401 aaaatctagg tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct
    26461 ctgctatttc cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc
    26521 gaaaacccat gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct
    26581 ttgtcccaaa tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt
    26641 ttgttcctaa tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg
    26701 ccttaggtac tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg
    26761 gctttatcgc agaattattt ggcattcgta cagttttctt actggttggt agttttctat
    26821 ttttagctgc tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg
    26881 aaaaggctat tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca
    26941 atctcttttt aaccagtttt gtcatacaat tttcagccca atcgatcggc cctattttag
    27001 ctctttatgt acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg
    27061 tgtccagtat gggcttttcc agtatgatga gtgcaggagt tatgggaaag ctaggtgaca
    27121 aggtgggcaa tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc
    27181 tttgtgccaa tgcctctagc ccgcttcaac taggactcta tcgattcctc tttggcttgg
    27241 gaaccggtgc cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg
    27301 gcatttcgag ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc
    27361 ccatggcagg ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacaa
    27421 gcctttgtgt tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag
    27481 taaaggaaat ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg gcagtatcaa
    27541 ttacctaacc agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg
    27601 tcccaaggaa agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa
    27661 tagggatttt aaggagtttg atatgtataa cctattatta accattttat tagtattatc
    27721 tgttgtgatt gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt
    27781 tgatgccagt tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat
    27841 gcagcgtttg acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt
    27901 attatcaagt agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta
    27961 aaggatgttt gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg
    28021 aaagatagaa taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct
    28081 caggctttgg gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta
    28141 atggaaagaa agcaccagat tcgctttgaa gaagatggta gtctgacatt agaaattaag
    28201 aaaaaacatg agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt
    28261 gttagtctgg aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct
    28321 attgatggtg ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca
    28381 gcagcagaag ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa
    28441 atcgttctgg atcaggaaaa gcctaagtat gctggctata ttcgttcaaa aaatcagaaa
    28501 atcagtcaac cgatttatgt taagaaacca gccctaaaat tagaaggaac agaagttctc
    28561 aaagtcttta tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc
    28621 gatgtagtgg ggcactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg
    28681 gacattgtat ctgagtttcc agaagctgtt gtcaaggaag cagaaagtgt gcctgatgct
    28741 ccgtctcaaa aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt
    28801 gacggtgcgg atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc
    28861 aatctggagc ttggggttca catcgcagat gtttcctatt atgtgaccga gggttctgcc
    28921 cttgacaagg aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca
    28981 atgcttccag aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg
    29041 acccagtctg ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca
    29101 caaacagtta tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct
    29161 ggcgatgaag aaaagagaaa agaataccat aaaattgtac caagtatcga actcatggcc
    29221 aagcttcatg aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc
    29281 aatgaagcga agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag
    29341 cgtggcattg ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc
    29401 gaacatttca gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct
    29461 gaaaaggttc agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatgggact
    29521 gccagtgaga ttagtcagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct
    29581 tatgcagatg tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag
    29641 cacaatcacg gccactatgg actagctgct gactattata ctcactttac cagtccaatt
    29701 cgtcgttatc cagaccttct tgttcaccgt atgattcggg attacggccg ttctaaggaa
    29761 atagcagagc attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa
    29821 cgtcgtgcca tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa
    29881 gaatacgtgg gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt
    29941 gtcgaattgc caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat
    30001 catttcaatg agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg
    30061 ggtcagcaga tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt
    30121 tcattcgtac ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcatagt
    30181 ggcagagggc gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaatcagga
    30241 cgctcaaatg ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct
    30301 ttttacaagg aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt
    30361 cgcacaaaat aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat
    30421 ggtcctgact ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg
    30481 ctttgctcaa gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga
    30541 agagggcaat atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa
    30601 gcaaattcaa aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa
    30661 ggtctatata aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga
    30721 ctatgacaaa cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat
    30781 gaaagctgtt aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa
    30841 acgcatgcct ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac
    30901 aaaagttggg acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt
    30961 gacagaagaa ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat
    31021 ggcccaacct caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt
    31081 ggaattttat tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca
    31141 ttcagaggtc ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg
    31201 tggtcagggg cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga
    31261 tcaaaatgga ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat
    31321 gcctgttggc ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt
    31381 ttcaacagtt gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat
    31441 gcaggagaaa accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga
    31501 ttatccttgc tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta
    31561 caaggattgg gaattggtta agtacaatga aaatccaggc catttgcacc gtcgcgatga
    31621 gaatggcaat cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac
    31681 acacatgaag attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag
    31741 gagggaattc atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga
    31801 taaacttgag aagcaagcat acacctgccc agcttgtgga ggccagatcc atttgcgtca
    31861 aggaccaagt gtacggacgc attttgccca taaattctta aaagactgtg attttttctt
    31921 tgaaaatgaa agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa
    31981 agagacaaag gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt
    32041 tgtaaatggc aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa
    32101 agagcgaagt gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa
    32161 actgtggctc aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa
    32221 catgggcttt tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct
    32281 gatttaccag gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca
    32341 aggtagttta ttggaaatat tgcgtcttcc ctataagaaa caaaaaatat ctcattttac
    32401 agtttctgag gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct
    32461 cttttggatg aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg
    32521 actgaaagaa tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca
    32581 agacttgact agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga
    32641 ttggcaaaag ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga
    32701 atagaaagga tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac
    32761 atgggatcta tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt
    32821 aacagaacaa ttggagacag tagtccagta tgaaggccat ctcttggata gtgcggataa
    32881 cctactagaa atcactgaat tttctcttga aatggaacgc cagatggaga agctttacgt
    32941 ttatgctcat atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc
    33001 caaggccatg acactctaca gccagttaga ccaagccttt tcattctatg agcctgaatt
    33061 tatggagatt agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt
    33121 ttatcaacac tattttgaca agctcttgca aggcaaggat cacgttcttt cacaacgtga
    33181 aaaagaatta ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat
    33241 cttggacaat gcggatattg tgttccctta tgtactagac gatgatggta aagaagttca
    33301 actatctcat gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg
    33361 tgcctatcaa gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt
    33421 gcaaaccaat gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg
    33481 tcatgcagcc ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc
    33541 agttcgcaag catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg
    33601 gatttcagat ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt
    33661 tacctaccaa gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta
    33721 cttgagccgt gtcaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg
    33781 caagcgttca ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa
    33841 ctggcaggac aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca
    33901 ttcaagctat actcgtgaaa ctcagcctta tgtttacgga gattactcta tctttttggc
    33961 tgagattgcc tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga
    34021 agacgacgca acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt
    34081 tttccgccaa actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg
    34141 ggaggtcttg acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta
    34201 tggtttgagt aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt
    34261 ctactataac tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc
    34321 tgaaaaaatt gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc
    34381 aggtaagtcg gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga
    34441 agactacctc aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct
    34501 tgttgaaaaa ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata
    34561 acatgcgtcg tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc
    34621 aagtcacagg tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta
    34681 ttccccatga aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata
    34741 ttctggaaat tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa
    34801 atgctaagat tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt
    34861 ttgcccagtt tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct
    34921 tatctacact gacagagtct tatgatttcg tctttatgga ttctgccaag tctaaataca
    34981 tcgtctttct gccagaaatt ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg
    35041 atattttcca aggcggtgat gttgccaagg acattatgga agtccgtcga ggtcagcgaa
    35101 ccatctatcg aggccttcaa agactatttg acgcaacctt agacaattca gaactcaccg
    35161 caacattagt gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc
    35221 aattgcctga cagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga
    35281 gtaacactta tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac
    35341 tattatcagt agcaacttta gcagcttgtt cgaaagggtc agaaggagca gaccttatca
    35401 gcatgaaagg ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt
    35461 cagcccaaca agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct
    35521 cagagcttga tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg
    35581 aaaactacca acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa
    35641 ttcgtacaag taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag
    35701 atgaagccta taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc
    35761 gtcttaataa tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg
    35821 attttgctca attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag
    35881 aaattacctt tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg
    35941 ctttagatgt ggatggtgtt tctgatgtga ttacagcaac tggtacacaa gcttacagta
    36001 gccaatatta cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact
    36061 acaaagaaaa attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc
    36121 aaagcattat cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc
    36181 aaaatatctt tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa
    36241 acgaatagtc caaatcaatg agtcagggaa aaaaactcga cttcaggaaa aaatgaagca
    36301 aacattccca caataaaacg catagtacaa ggtttgtact gcccccaaaa gttagacaat
    36361 taatttatct gaaggattta gttctgtatt gcacagggct aagtcctttt agttttacct
    36421 taattctctt attgttctaa taatcaatat agtctataat ggcttgttcc aattgattaa
    36481 gtgatttaaa tgttttctca tagccataaa acatttcgga ttttaaaatg ccaaagaaag
    36541 attccatcct accgttgtct tggctgtttc ctttgcgtga catagatgct tgaattccct
    36601 tactctctag gaagcgatga taagaatcgt gttggtattg ccagccttgg tcactatgga
    36661 gaatcgtatt ctcgtagtgc ttctctttga atgcctgttc caacattaac gatcaatcaa
    36721 tttaatcatg tacctaatat tagaattgtt tatcccaaat ttatttgaaa gcttctctaa
    36781 gcta
//
LOCUS       DAVHSH010000014        34816 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000014 DAVHSH010000000
VERSION     DAVHSH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.014"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            88..1980
                     /gene="pepO"
                     /locus_tag="VVR08_000848"
     CDS             88..1980
                     /gene="pepO"
                     /locus_tag="VVR08_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU6074793.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2103..2732)
                     /locus_tag="VVR08_000849"
     CDS             complement(2103..2732)
                     /locus_tag="VVR08_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6074794.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHNIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3726..5948
                     /locus_tag="VVR08_000850"
     CDS             3726..5948
                     /locus_tag="VVR08_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU6074795.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5978..6421
                     /locus_tag="VVR08_000851"
     CDS             5978..6421
                     /locus_tag="VVR08_000851"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU6074796.1"
                     /translation="MKIIIQRVKKAQVSIGGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6460..6821)
                     /locus_tag="VVR08_000852"
                     /pseudo
     CDS             complement(6460..6821)
                     /locus_tag="VVR08_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014307.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6895..7308)
                     /locus_tag="VVR08_000853"
     CDS             complement(6895..7308)
                     /locus_tag="VVR08_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074797.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFECLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(7410..8087)
                     /locus_tag="VVR08_000854"
     CDS             complement(7410..8087)
                     /locus_tag="VVR08_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU6074798.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGLWTALVPFGLISLTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKATIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            complement(8264..8914)
                     /locus_tag="VVR08_000855"
     CDS             complement(8264..8914)
                     /locus_tag="VVR08_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU6074799.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNIDIAKQLYVEKIN"
     gene            9026..9868
                     /locus_tag="VVR08_000856"
     CDS             9026..9868
                     /locus_tag="VVR08_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6074800.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9944..10381
                     /locus_tag="VVR08_000857"
     CDS             9944..10381
                     /locus_tag="VVR08_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU6074801.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10449..10751
                     /locus_tag="VVR08_000858"
     CDS             10449..10751
                     /locus_tag="VVR08_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074802.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10842..11915)
                     /locus_tag="VVR08_000859"
     CDS             complement(10842..11915)
                     /locus_tag="VVR08_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU6074803.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            12071..12748
                     /locus_tag="VVR08_000860"
     CDS             12071..12748
                     /locus_tag="VVR08_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6074804.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLIDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12741..13715
                     /locus_tag="VVR08_000861"
     CDS             12741..13715
                     /locus_tag="VVR08_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6074805.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLEIYFL
                     YFFLLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13764..15707)
                     /gene="thrS"
                     /locus_tag="VVR08_000862"
     CDS             complement(13764..15707)
                     /gene="thrS"
                     /locus_tag="VVR08_000862"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU6074806.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDSLPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEKEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15765..16088)
                     /locus_tag="VVR08_000863"
     CDS             complement(15765..16088)
                     /locus_tag="VVR08_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6074807.1"
                     /translation="MKLQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFFSDKEKQLN
                     VRTWK"
     gene            16947..17438
                     /locus_tag="VVR08_000864"
     CDS             16947..17438
                     /locus_tag="VVR08_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEU6074808.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVIGGAGS
                     LYIDETKMTRLLDTPDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGN"
     gene            17717..17986
                     /gene="rpsO"
                     /locus_tag="VVR08_000865"
     CDS             17717..17986
                     /gene="rpsO"
                     /locus_tag="VVR08_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU6074809.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18799..19413
                     /locus_tag="VVR08_000866"
     CDS             18799..19413
                     /locus_tag="VVR08_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU6074810.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19706..20455)
                     /locus_tag="VVR08_000867"
     CDS             complement(19706..20455)
                     /locus_tag="VVR08_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU6074811.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWVRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20588..22924
                     /locus_tag="VVR08_000868"
     CDS             20588..22924
                     /locus_tag="VVR08_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU6074812.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDVQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23026..23703
                     /locus_tag="VVR08_000869"
     CDS             23026..23703
                     /locus_tag="VVR08_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU6074813.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23690..24487
                     /locus_tag="VVR08_000870"
     CDS             23690..24487
                     /locus_tag="VVR08_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU6074814.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24504..25607
                     /locus_tag="VVR08_000871"
     CDS             24504..25607
                     /locus_tag="VVR08_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU6074815.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            25608..25688
                     /locus_tag="VVR08_000872"
                     /pseudo
     CDS             25608..25688
                     /locus_tag="VVR08_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            25953..26972
                     /gene="galE"
                     /locus_tag="VVR08_000873"
     CDS             25953..26972
                     /gene="galE"
                     /locus_tag="VVR08_000873"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6074816.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26974..27939
                     /locus_tag="VVR08_000874"
     CDS             26974..27939
                     /locus_tag="VVR08_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6074817.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(27990..28196)
                     /locus_tag="VVR08_000875"
     CDS             complement(27990..28196)
                     /locus_tag="VVR08_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU6074818.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28248..28724
                     /locus_tag="VVR08_000876"
     CDS             28248..28724
                     /locus_tag="VVR08_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU6074819.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28733..29404
                     /locus_tag="VVR08_000877"
     CDS             28733..29404
                     /locus_tag="VVR08_000877"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU6074820.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLVVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29534..29872
                     /locus_tag="VVR08_000878"
     CDS             29534..29872
                     /locus_tag="VVR08_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU6074821.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29875..30504
                     /locus_tag="VVR08_000879"
     CDS             29875..30504
                     /locus_tag="VVR08_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU6074822.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30744..31895
                     /locus_tag="VVR08_000880"
     CDS             30744..31895
                     /locus_tag="VVR08_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6074823.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32208..32957
                     /gene="truA"
                     /locus_tag="VVR08_000881"
     CDS             32208..32957
                     /gene="truA"
                     /locus_tag="VVR08_000881"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU6074824.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFILDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            32947..33720
                     /locus_tag="VVR08_000882"
     CDS             32947..33720
                     /locus_tag="VVR08_000882"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6074825.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33698..34159
                     /locus_tag="VVR08_000883"
     CDS             33698..34159
                     /locus_tag="VVR08_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6074826.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34383..34760
                     /locus_tag="VVR08_000884"
                     /pseudo
     CDS             34383..34760
                     /locus_tag="VVR08_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10080 a         6540 c         7980 g        10216 t
ORIGIN      
        1 aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt taagataaat
       61 gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt ttatgatgct
      121 atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca aactggaggt
      181 tttgttgatt tagaccagga aattgaagac ctgatgttgg cgacaacaga caagtggtta
      241 gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata ccaccgccta
      301 gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc actccttaaa
      361 gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga gtttgagctt
      421 gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga tgctagaatc
      481 aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta ctatgcagaa
      541 gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc aaatctcctc
      601 aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag acttgaattg
      661 gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata tgctaaactc
      721 tatcatccat attcttacga agatttcaag aaattcgctc ctgccctacc tttggatgac
      781 ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga ggaacgtttc
      841 tggcaagcag cagagcaatt ctacagtgag gaagcctggt ctctccttaa agcaaccttg
      901 attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg tgttttgtct
      961 ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt caaagcagct
     1021 tatcatctag cacaagaacc tttcaagcaa gccctgggtc tttggtacgc ccgtgagaag
     1081 ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat tgatgtttat
     1141 aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca ggctatcgtg
     1201 aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc acgttacaag
     1261 gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt tgcgcgtgtg
     1321 gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga atggggcatg
     1381 cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt ctttccagcg
     1441 gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa ctacggtggt
     1501 attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg ggcttccttt
     1561 gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc cttcaaggag
     1621 aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc aaccattaac
     1681 ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc agcgcttgaa
     1741 gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt cggtcgcatc
     1801 tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga tgtgcacgca
     1861 ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt tacaacctat
     1921 gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat tatttggtaa
     1981 tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac cttgatagga
     2041 tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt gtcatcatct
     2101 tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg accatgtcct
     2161 ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatattatg aaggagttgc
     2221 tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag agcatctccc
     2281 gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga gtgccctggg
     2341 gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa gacaaaggtg
     2401 tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag accggagaga
     2461 ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac aggaggattg
     2521 ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc gtgggtcaag
     2581 agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc ttcccaatga
     2641 ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt attttcatag
     2701 gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa gaatgtacta
     2761 atactcttcg aaaatctctt caaaccgcgt caactttatc tgcaacctca aagcagtgct
     2821 ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag tataaattaa
     2881 gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa ccagcatgac
     2941 tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa ttgcccttca
     3001 taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag agtgctaccg
     3061 tagttggctt ctcatttgtc gctatattca ctataagtta tcctactggg caggttctgg
     3121 tcgttagcat agtattgaac gagtttttta tagctttgct ggctgaatag gaacaggcag
     3181 caaactccta acattaggag agcaaagata gaaatagcag tttttttcat aggtattctc
     3241 cttataaact aaaggataga agaaagtatc ttgaggattt ttatactctt caaaaatctc
     3301 ttcaaaccgc gtcaacgtcg ccttgccgta tatatgtgac tgactttgtc agtcttatct
     3361 acaacctcaa agcagtgctt tgagcaacct gcggctagtt tcctagtttg ctctttgatt
     3421 ttcattgagt attaattcca aaatccagtc aaggtaccag tgtatgtgat acgagttcca
     3481 ccgtttatct ttcgtatctt caatggaatt ggggaaatca gaaagtcttt gggttacaat
     3541 atggtttccg ttcttctatc tctccttcta tcacctaagt ttaaaatcta acttcgtagt
     3601 atattatggg tcaataattc agaattatca agcaattttg aattattttt ttcttattct
     3661 gttccaatct agttttcata ttcttaaaaa agtgataaaa tggtaggaag aattggagag
     3721 tagagatgcc gaaagaagtg aatttaacag gcgaagaagt tgtcgcttta accaaagaat
     3781 atttaacgga agaggatgtt cattttgtcc ataaggcctt ggtctatgct gttgaatgcc
     3841 acagtggtca atatcgcaaa tcaggcgagc cttatatcat tcaccctatc caagtggcag
     3901 gtattttagc taagctaaag ctggatgctg taacagtagc ttgtggattc ttgcatgatg
     3961 tggtggaaga tacagatgcg accttggacg atttggaaag agagtttggt cctgatgtgc
     4021 gggtgattgt tgacggagtt accaagcttg gcaaggtcga gtacaaatcg atcgaggagc
     4081 aattagcgga aaatcatcgc aagatgctca tggccatgtc tgaggatatc cgcgttattt
     4141 tggtcaaact gtctgaccgc ttgcacaata tgcggaccct gaaacatctt cgaaaagaca
     4201 agcaggagcg tatttccaaa gaaaccatgg aaatctatgc cccacttgcc catcgtttgg
     4261 ggatttccag tgtcaaatgg gaattagaag acttgtcttt ccgttatctc aatccaacgg
     4321 agttttacaa gattacccat atgatgaagg aaaagcgcag ggagcgtgag gccttggtgg
     4381 atgaggtagt cacaaaatta gaggagtata cgacagaacg tcacttgaaa gggaagattt
     4441 atggtcgtcc caagcatatt tactcaattt tccgcaaaat gcaggacaag agaaaacggt
     4501 ttgaggaaat ctatgatctg attgctattc gttgtatttt agatacccaa agtgatgttt
     4561 atgccatgct tggttacgtg catgaatttt ggaaaccgat gccaggtcgc ttcaaagact
     4621 atattgccaa ccgcaaggcc aatggttatc agtctatcca tacgactgtt tatggaccaa
     4681 aagggccgat tgaattccag attcgaacca aggaaatgca cgaggtggct gagtacgggg
     4741 ttgcggctca ctgggcttat aagaaaggta taaaggggca agttaacagc aaggaatcag
     4801 ctattggaat gaactggatc aaggagatga tggagctcca agaccaggct gatgatgcta
     4861 aggaatttgt ggactctgtt aaggaaaact atctggctga ggagatttac gtttttaccc
     4921 cagatggagc tgtccgttcc cttcccaaag attcaggacc gattgatttt gcctacgaaa
     4981 tccataccaa ggtcggtgaa aaagcaactg gtgccaaggt caatggccgc atggttccac
     5041 tgacaaccaa gttaaagaca ggggatcagg ttgaaattat cgccaacccg aactcctttg
     5101 gacctagccg tgactggctc aatatggtca agactagcaa ggcgcgcaat aagattcgcc
     5161 agttctttaa aaaccaagat aaggaattgt ctgtcaacaa gggtcgtgag atgctgatgg
     5221 ctcagttcca agaaaatggc tatgtggcaa ataaatttat ggacaagcgc cacatggatc
     5281 aagttctgca aaagaccagt tacaagacag aagactccct ctttgcggcc attggttttg
     5341 gggaaatcgg tgcgattacc gtctttaacc gtctgactga aaaggaacgc cgtgaggaag
     5401 agcgtgccaa ggccaaggct gaggcagagg agcttgtcaa aggtggcgag gtcaaggttg
     5461 aaaataaaga aactctcaag gtcaagcatg aggggggagt ggttattgaa ggtgcttctg
     5521 gtctcctagt gcggattgct aagtgttgta accccgtgcc tggtgacgat attgttggct
     5581 acattaccaa gggtcgtggt gtggctattc atcgtgtgga ctgtatgaac ctgcgtgccc
     5641 aagaaaacta cgagcaacgt ctccttgatg tggaatggga agaccagtac tctagctcaa
     5701 ataaggagta tatggcccat atcgatatct acggtctcaa ccgtacagga ctgttgaacg
     5761 atgtactgca agttctttca aatacaacca agaatatttc aacggtcaat gcccaaccaa
     5821 ccaaggatat gaagtttgct aatatccatg tgtccttcgg tattgccaac ctctctacac
     5881 tgaccacggt tgtcgataaa attaagagtg tgccagaagt ttactctgtc aaacggacca
     5941 acggctagtt gtcctagctc ttactagaaa ggctattatg aaaatcatta tccaacgggt
     6001 taaaaaagcc caagtgagta taggaggcca gattcaggga aaaatcaatc agggactttt
     6061 attgctggtt ggtgttggac cagaggacca agaggaagat ttggactatg ctgtgagaaa
     6121 actggtcaat atgcggattt tttcagacgc agaaggcaag atgaacctgt ctgtcaaaga
     6181 tattgaagga gaaatcctct ctatttctca gtttaccctc tttgcggata ctaagaaagg
     6241 caatcgtcca gcctttacag gggcagctaa acctgatatg gcatcagact tctatgatgc
     6301 tttcaatcaa aaattagcgc aagaagtgcc cgttcagaca ggtatctttg gagcagatat
     6361 gcaggttgag ctggttaata acggacctgt taccattatc ctagatacta aaaagagata
     6421 agaaagacca agcccagtcg gcttggtctt tctcatcgat cataaaatac tccaaaaaga
     6481 aatcggttct tgatatgctt gggggaagtc tcttttcagg ctttggcaga tgcgatagga
     6541 agggatgaga tgtcctagga tgaggagagt tccctgaagg aaaagtggaa tatcacttaa
     6601 agacaccaag gagagaatca tcaggctatc ccataggaga atttgtaaag caaaacgcca
     6661 gaatctcggt ctaatctggg aatagagttg actaaagtgg tcacaaagtt ggtttgaaag
     6721 ataggtcaat agcacaggat gaaagaaaat gagccaaccg ctataaatca aaatccagtc
     6781 ccaagtaagc cccccttttt aaatgtcaaa aatgccagca tgattccatc aatgacaagg
     6841 agttgaatgg ttttgatgaa gatgattttt tttcatgcta aaacctcctt ttccttagag
     6901 acactcccat aaagagatgt gtttgtcgta aaagtctgga tagttttctc ctaggtagtc
     6961 agctgtcata taataaaaag tagaatggca agcagtgata attggcataa gagatgaaaa
     7021 acgctgagaa ctaatgaagg ctaagagaac aaaaaataga aaatcaatgg tgagaacccc
     7081 taaatagtag aagcgaatct ttttattgat ttgaggataa atctcagcga attgatgttt
     7141 gagtcggacg accaagagaa atagcaggag tccttgagca aggaagaaaa ttaaaccaga
     7201 gagcaagagg cactcaaaag atgtctcgag tctagtgata aaaaatgcaa atagtagcaa
     7261 atcaataact gcaattgcta taaaatggat tctatagagt tttttcatga caagaccttc
     7321 ctcttttatc taacttcatt ctactccaaa agaatgggag ttacaactaa aatgataaaa
     7381 atagcagaag ggagattctc ttaagttggc tagtattctt tatttgagtt tccttctatg
     7441 tatctaactt cttcatcatt ccagacaaat aaagctccga ttgcattgag gatataaaag
     7501 atgtatttac cgatattggc gaagtttcct tgaataccag cttttgtcag ctgaacgaaa
     7561 ttgtaaatca accaaaagcc ccactgagtt gttagtttca atgcattcaa agcattggca
     7621 atgagggaca gtgcaaaggc aatagttgtt acgtaggcaa ggagattcat cttgccccca
     7681 tatccgatat agttggttac aaaggcaaag aggaaggcga tgatggaaat gatgatggcc
     7741 gccaatttta cctgtttttg gctcatttgg ttgggtctgc cttcttgcga agctttccat
     7801 ttctttatag caaaggtata aatgaggaag gtgacgggat aggtaatgat ggtcgcctta
     7861 tttccaagga tataatcaat agcaccggac aaaatggtat taacaatacc aaagtaattt
     7921 ccccatttgc ttaatttccc cgtgaaacga gtggacaaca tggaaatccc aacgttggtt
     7981 aaggaaatca atccaaaggg tacaagagct gtccatagtc cccagtctac aaatttatcg
     8041 aggcgtgagt tgagataacc agatgcaatc gcaatcccaa cgaccaaagc aaccccgaag
     8101 aggtcaaatc atttagatgt agcaaaaatt tttagtgatt ttttcatagg ttaaactacc
     8161 tttctttttt tcaaatactc taccaccaaa tgaaagtaaa atcaaatgat agaaataaaa
     8221 ccctgaaaat aaaactttca gggttggtag gggacttgag aaattagttg attttctcga
     8281 catagagttg ttttgcaatg tctatattca cttgtaaatc ctcgtcgtta ctgaggatag
     8341 tgaaggtatt gctgaagcca tcaaactgct tgacttggag ctggtcaccg atgtgaagtg
     8401 agtgcttgtc cagataatgg agaatgtcaa aactatcgtg cacccgagtc aggcggtagg
     8461 cgccagcttc cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct
     8521 tggcaggaat agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc
     8581 tttccacgaa caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt
     8641 cacttgtata gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga
     8701 gctcagagac cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta
     8761 ggatgagatt ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt
     8821 gcatgcgagc cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa
     8881 tacattttag atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta
     8941 tctagtatat caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg
     9001 caagagaaaa aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg
     9061 aaataccacc gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata
     9121 ctggcttttg ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt
     9181 ggatcaacta ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg
     9241 tgtccgtaag gaattggata gtactcgccc cagtcaacgc tatctcttgc gccagtgcca
     9301 gtatgtttta gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca
     9361 aattcatcgt cagtttgggg atttgacggt gggaattagc catcatctgc ctgataagaa
     9421 ctgggggcga gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca
     9481 tcctccctgt gatattgctg tttatggaca tattcaccag cagttgcttc gttacgggac
     9541 tggtgggcaa ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca
     9601 gctacggaag gacttgcggg cccagtatat gattttggag tttgatgaca aaggcctggt
     9661 agatatggac ttccgacggg tagactacga tgtggcagcg gaattgcagc tggctaaaga
     9721 cctgagactt ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac
     9781 tcatcatcag gaatttttga gagaattggc tcagaaagag ggctgcgatc gggagttaga
     9841 cgactggttg aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa
     9901 aagaagagta gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag
     9961 atttaccatt gcgactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt
    10021 gaccagtgat tttctggctg ctagtgtcgg ggtcaatcct gtcattatca gaaagatctt
    10081 gtcccagttg aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat
    10141 tgtcaaggac cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg
    10201 taagacaggt caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc
    10261 tcatattcat gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga
    10321 acttggtcaa accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta
    10381 agagggataa atgccctctt ttttctttgg ataattatga taaaatgtag ctattaaagg
    10441 agtaagaaat gtatctcgtt ataggaattg tattagcctt tatagtgtca ttttggaagg
    10501 ataatagaag tttgtggaat ccagtattat ttttattatc cctcatttca agttattttt
    10561 atctatccta ccttttttat aaaaatggat acgagaatgt tcagttagct ttttatgtat
    10621 ttgcctttgt cttacttcct tttttgcttt ttctaagtgg catcttttta atctataatg
    10681 gggtcatttt gttgaaacga gagggacgtt ccaagcccca ttatctctca atgctctttg
    10741 atttttattg actattagat tctatttaaa aagacttata atgcacatga aagtatgtat
    10801 tctaggtctt ttgttttgta tacatttaat tttcaagagt attatctatt tttccatgcc
    10861 tggtaacgag tatcaatcaa taactgggta aggcgaccca aggtttctct ttcttctgga
    10921 gtgagggatt gagcttggac aaagagatga tgaatgtatt caagcgcctt taaggaagcc
    10981 aagtcattga tagagctaat accagcatca agaatagtgc caaagaagag gtcgaagtag
    11041 agctgaagtt cttcgtcagg gactgtggcc acccattctt taaaggttgt gtctacttgc
    11101 tggctatcac tgttggtctt atccagttgg acgaagtgct tgtcctcaat ctgccaacta
    11161 aaggtatcgt gctgggcgat gccacccagg gcagtactct gaacgatgat ttggtgagca
    11221 ggaatttcca gcatcatacc gataatggaa ccttgtggaa tgaatatctt gcttctatcc
    11281 attatccttt gataacccgc agtctgtgtc aattcttgat ggagaccagg tgcatcaaat
    11341 gtataaactg ctgtgatctg attttgcaaa ctttgctcaa tttggctagc agcatagata
    11401 gcgagatttc ctcccttgga atgcccagcc agaataacct tttgcttagg atgatgggca
    11461 aaaaagttct ttaaatagcg aagggcgtgc ttttgagcag gaatttcctt catataggtc
    11521 aggtggaaat cttccttcca gccaatgata ctgtcatctg tcccacgaaa gacaatcaga
    11581 taggtatcga ggctgacacg ataagtcata gccgcaaatt gcttttgcag ttcagggtcg
    11641 atgtcgttga taaaatggga gagtttgcaa tttttgaagc gcttgtgttg agccaattca
    11701 tctaataatt gaaggcgatt tttgctagta agcatggtgg gctctcttgg aacctgaggt
    11761 gctagatcta aaagacgttg aggaagtgtg gagaccagat tatcaaagga gaggtaggtg
    11821 atttctatta aggttagaat gtctaactca ttcaagggaa ggtcgtaata agaatcatat
    11881 gcgacatctt tcagatagtc aaaaatattg gccataagag ctcctttctt tttatttatc
    11941 ttagcaaatt tccctcaaat tagctagtag cattgcctgt ttgtactggc taaaaacagg
    12001 ctatttcaaa ttcagtttca gaccatctgg catggaaaaa tctgttataa taatggaaaa
    12061 ggagaagcgc atgcacaaga ttttattagt ggaagatgat caggtcattc gtcaacaggt
    12121 cgggaaaatg ctctctgaat ggggatttga agtggtcctg gtagaagact ttatggaagt
    12181 tttgagtcta tttgttcagt cggaacctca tctggtcctc atagatattg gtttgccctt
    12241 gtttaatggt tatcactggt gtcaggaaat ccgcaagatt tccaaggtac ctatcatgtt
    12301 tctttcttcg agagaccagg ctatggatat tgtcatggca atcaatatgg gggcagatga
    12361 ctttgtgacc aagccttttg accagcaggt tcttttagcc aaggttcagg gcttgttgcg
    12421 tcgttcctat gagtttgggc gtgatgagag tttgctggaa tatgctggtg ttatcctcaa
    12481 taccaaatcc atggatttac attatcaagg gcaagtcttg aatttgacca agaacgaatt
    12541 ccagatttta cgcgtgttat ttgagcatgc aggcaacatc gtagcacgtg acgacctgat
    12601 gcgagaactt tggaacagtg actttttcat tgatgataat accctctctg tcaatgtggc
    12661 tcgtttgcgt aaaaagttgg aggagcaggg attggtagga tttatcgaga ccaagaaagg
    12721 aatagggtac ggattgaagc atgcttgatt ggaaacaatt ttttctagcc tatctgcgct
    12781 cccgtagtcg tctttttgtc tatctgcttt ctttggcatt tctggtctta ctctttcagt
    12841 ttttatttgc cagtctagaa atttacttcc tctacttttt cctcttgtgt tgctttgtaa
    12901 ccatcttatt tttcacttgg gacatattgg tggaaacgca ggtctatcgc caggaacttc
    12961 tctatggaga gagggaagcc aagtctcctt tggaaatagc tttagcagaa aaattagaag
    13021 cgcgtgagat ggaactctat cagcagaggt caaaagcaga aagaaaactg acggatttgc
    13081 tggattacta taccttgtgg gtccatcaga taaagacccc cattgcagcc agtcaacttt
    13141 tagttgcaga agtggtcgac cgccaactga agcagcagct agaacaggaa attttcaaaa
    13201 tcgactccta taccaaccta gttttacagt acctgcgttt agaaagtttc catgatgatt
    13261 tggtcttaaa gcaggttcaa attgaggact tggtcaagga aataattcgt aaatatgctc
    13321 ttttctttat tcaaaaaggc ttaaatgtta atctacatga ccttgataaa gaaatcgtga
    13381 cggataaaaa gtggctgcta gtggttattg agcaaatcat ctcaaacagt ctcaagtaca
    13441 ccaaggaagg tggtctggag atttatatgg atgaccaaga gctttgtatc aaagatacgg
    13501 gaatcgggat aaaaaacagt gatgtcctcc gagtatttga acgtggcttt tcaggataca
    13561 atggccgttt gacccagcag tcctctggac ttggccttta tctatctaag aaaatttctg
    13621 aagaactggg gcaccagatt cgtatcgagt ctgaggtcgg aaaaggaacg acagtgcgga
    13681 ttcagtttgc tcaagtgaac ttagtccttg agtaaaaata gatgagaaaa agcctccaga
    13741 ttggaggctt ttatgctaga ctcttatttc tcaacgcgtg atttgttggc gatatcagct
    13801 aggatagctt gaacaaaatt atcaactgag acagtttgtg tttctttttg gccgtagcga
    13861 cgaacgttga ctgtttcgtc ttccatttct ttgtctccaa caattaattg gtaaggaatc
    13921 ttgctggttt gtgaagcacg gatcttgaac tgcatttttt cattgcgctc atctacatct
    13981 gcacggacac cgcggtcacg gagtttcttg gctacttccc aagcgtagtc cacgtgtttt
    14041 tcgttagata ctgggatgag ggttacttgg tgtggtgcca gccatgttgg gaaggccccc
    14101 ttgtagttct caatcaagat agctgtgaag cgttccatag ttgagataac cccacggtgg
    14161 atcatgactg gacggtgatc ttcgccatca gctccgatat atttgaggtc gaagcgttct
    14221 ggcaacaaga aatcaagttg gatagtagaa agggtttctt cttttccaag ggcagtttta
    14281 atctggatat ccaattttgg tccgtagaag gctgcttcac cttcggcttc aaagtagtcc
    14341 acgcccattt catcaagagc tgcacgaagc atggtttggg cattttccca catctcatcg
    14401 ttatcaaagt acttatgagt atcttgaggg tcacgaagag agaggcggaa gcggtagtca
    14461 gtcaagttga agtcttcata aacatcgata atcaactgaa gggcacgttg gaattcttct
    14521 tggatttgtt ctggagtaac gaataggtga ccgtcgttga gtgacatttc acgtacacgt
    14581 tgaaggccag tgagggcacc agatttttcg taacggtgca tcataccgat ttcagcgata
    14641 cggattggca attcacggta agagtgaaca tggtgtttga aaacttggat gtggtgcgga
    14701 cagttcattg gacgaaggac aaattcttcc ccgtcaccca tgtccatggt tgggaacatg
    14761 tcttcttggt aatgatccca gtgaccagaa gtcttgtaaa gctcaacaga agcaagtggt
    14821 ggagtgtaga cgtgttggta gccagaagcc aactctttgt ttacgatgta gcgttccaat
    14881 tcacgacgga tagtcgcacc atttggcaac cagaatggca aaccttgtcc cacttcttgt
    14941 gaaatcataa agaggtcaag ctctttacca agtttacggt ggtcacgttc cttagcttct
    15001 tcacgcattt gaaggtagtt tttcaagtct ttcttgtcaa accaagctgt accgtagata
    15061 cgttgcatca tagcgttgtc gctgtttcca cgccagtaag caccagctac atggagaagg
    15121 tggaagattt ggatacgacc tgttgatgga acgtgaggtc cacggcagag gtctacatat
    15181 tcaccctgac gatagatagt caaaccgcct tcgtcttctg agtgttcttc aatcaattcc
    15241 aacttgtaag ggtcattttt gaagatttca cgtgcctcgt ctttagtcac ttcttcacga
    15301 atagatggga agttttcttt gacgattttt tgcatttctt tttcgatacg aggaaggtct
    15361 tcgttagaga tttgaccagc tgtgttgtca gtatcgtagt agaaaccatc ttcgatggct
    15421 ggaccaactc ccaagtgaat gtctgggaaa agacgacgag ctgcttgggc gaacaagtga
    15481 gctgctgagt gacgcaagat tggaagggaa tcttcgtgat caggtgtcac aatttcgatg
    15541 cttccatctt cagtgatagc gcgagtagtg tcgatgagtt tgccgttgaa tttaccagcc
    15601 aaggcttttt tagctaggga attgctgata gattgggcaa tttcaaaagt tgttacgcca
    15661 gattcgaatt cacgaacagc gccatctggg aaagtaatgt taatcatgat gttctccttt
    15721 tttattattt catagtttct aagcattgat tttttatcat cagactactt ccaagtccta
    15781 acgttcaatt gcttttcttt atcagagaag aagttttcca tttccgtcag aatgtctata
    15841 tccaaacgtt gagaaagttc taatagccac cagatatttt ctgaaagttt ttgttccagt
    15901 gtgtagggtg tttcatcata gtagcgtcct tgctttgtca tcaccagtcg ttggaaattt
    15961 ccaatatcat tagataaagc caagaggtct tcttctaccg tccacttgaa atcatgatgc
    16021 ttaacttcca gttcgtgata agcttgtcgg attgcccaac tgcgctccac taattcttgc
    16081 aacttcataa ttagtatcct aataaaaaaa tgcgacatcc tcgaaaggac gtcgcaacgt
    16141 ggttccacct tcatttatgt acctcaaaag agagggacac ctctgattgg ctctaacgtg
    16201 gccaccgttt tatgttttca taaaaaactc aagagtagta tcagtttaga cttcctatgc
    16261 gtttccagca accacgcact ctctagtaga aagggactaa gtgacttgtc tctatggatt
    16321 attatagcat gattgtgaga tttttcaagg attttgtgaa agttttttgt ttttcatttt
    16381 ttgtagaata tgcttgatgc taataccaga atccatgccc accagagcaa ctgtttcata
    16441 gattagcaag taaattagta taaactcacc aaaggttatg atagtaaagt aaaagagcag
    16501 tccgttacca actaaccatc aaagtgagaa acggaaacgg tagctataga gtaacgatac
    16561 aatcaagatt accagaggtg taaagaagag aagattgttt atatagtgta agggggtcag
    16621 aaacaactag caagaacaac tcataaagtg gccaataaaa gaataatatg accagatagt
    16681 aggggagatg ggaatagaat ctacgcatga taatcacctc gttttaaaaa aacagacaac
    16741 ttagatctct tgctatgatt attatagcat gtttaaaaca agaaagtaaa tttgttgaca
    16801 aagaagattt ttcttttcac tagaatcatg gttagttttc ttggtagaaa tattttgata
    16861 ataattaagc aagactattg acattgatta ttaagagtgt cacaatttct gtaactaaaa
    16921 taattacaac aagagaggta taaaaaatga aactagcagt tattgcagca aatggacaag
    16981 cggggaaagc aattgttgaa gaagtagtca aacgaggaca tgaagtaacg gctattgttc
    17041 gttctgaaaa caaaagtcaa tctgagtcta ttattaaaaa agatttattt gagttgacaa
    17101 aagatgatct tactggattt gatgctgtta tttcagcgtt tggtgcttat acaccagata
    17161 cgctaccgct ccacagcaaa tcaatcgaac tatttaatca gcttcttgct ggaacacaga
    17221 cacgttttct agttataggg ggagcaggaa gcctttatat agatgaaaca aaaatgacac
    17281 gacttttaga tacgcctgat tttcctgaag aatttaagcc actagcaaaa gctcaagcgg
    17341 atgaattgga tcttcttcgt acaaaaaata atctcaactg gacttttgtc agtcctgctg
    17401 tagattttat tcccgatggt gaaaaaacag gaaactaaat tctagcagga gaaattttta
    17461 ctactaatgg aaaaggaata agccagatta gttatgcaga ttatgctatt ggattggtag
    17521 atgaacttga aaaaggtcat catataaaag aacgtatctc tttacttgaa aaataataac
    17581 tatgagagta ttaatgtttg acagaaaatt taaatcttgg taaaataggg attgtcgtaa
    17641 agacaaataa cttcttcttg gttacaggca tgccaacctg tcactcggat gaagccaaat
    17701 aaaaaggaga aacatcatgg caatctcaaa agagaaaaaa aatgaaatca ttgcacaata
    17761 tgcacgtcac gaaggtgata caggttcagt agaggttcaa gttgctgtcc ttacttggga
    17821 aatcaatcac cttaacgaac acatcaaaca acataaaaaa gaccacgcta cttaccgtgg
    17881 attgatgaaa aaaatcggtc gccgtcgtaa cttgcttgca tacttgcgta aaaacgacgt
    17941 taaccgttac cgtgagttga tcaactctct aggacttcgt cgctaattca agatacaaag
    18001 gccgtcaaaa gcacaaagca aaaataggaa aattgacgaa gaaacttcag tttctaggag
    18061 attttatctt ttttgccaag tgcttaggcc gtgttcaatt gagcatatct tgataataaa
    18121 gctactctaa attgggtagc ttttttgcgt tgtcacctta cctcgatata ctcaagtata
    18181 atctttggtt acggttccta gcactgtaag gtaaaataaa ccagcttttc tcccttcggg
    18241 gagatttttt ttgtttcact gaaagtttcg tacgatcttc gcctcgtcgc ctagtctata
    18301 aacgatttat ctagcaagaa tcatgatgct aagggcgtca aaaatccgta tgaaaatagg
    18361 gaaatgacac agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc
    18421 cgggctcaaa tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca
    18481 attttggaga ctacaaaaac ctcaaacggt atcagctaat tacaccataa aggtgcgcag
    18541 ttactcggct tttcaagccg agtagctgta tgcaagcccc tagaagagcc cactctttac
    18601 aaagtaaagt atagtatgtt atactttaca tggaagtagt cactgaattc cagttagaaa
    18661 ttactttgta actacgtttt gaggaggagt aaaatgcttt cctacgttcg acattaccca
    18721 ctagcgatag ctaaattaat gtgtctgtgc tctcctaaaa tctgctgatt tattactgac
    18781 taatacagga gtttttttat gggacagaca atcatatctg ctattggtgt ttatatttcc
    18841 accagtatcg attatttaat tattttaatt attttatttg cacagctatc acagaataaa
    18901 cagaaatggc atatttatgc ggggcaatat ctaggcacag gcttacttgt aggggcgagt
    18961 ttagttgctg cttatgtcgt taatttcgtg cctgaagaat ggatggttgg attgcttggt
    19021 ttaatcccta tctatttagg gattcgcttt gcaattgttg gagaagatgc ggaagaagaa
    19081 gaggaagaaa ttattgaaag attagaacaa agcaaggcaa atcaactgtt ttggacagtt
    19141 acattgctga caattgcgtc tggcggagat aatttaggta tctatatacc ttattttgct
    19201 tcgttagatt ggtcacagac cctcgtggcc ttgcttgtgt ttgtaatcgg cataattatc
    19261 ttttgcgaga ttagtcgggt gttatcctct attccgttaa tattcgagac aattgaaaaa
    19321 tacgagcgaa tcattgtgcc cttagtattc attctacttg gactatacat catgtatgaa
    19381 aatggcacga tagagacttt tctgatcgtg tagatttttt tgtttcacta ggattttagc
    19441 ccgagctcaa atcagctctc tgattttcag agggcttttt cattgagtat aaatggacaa
    19501 tcttaaagtt actctattgt agagtggctt ttgatttgat taggagattc ttataaatat
    19561 agtaaaatga aacaaaaaca ggacaaatcg atcaggacag tcaaatcgat ttctaaaaat
    19621 gttttaagaa gtagaggtgt actattctag tttcaatttg atatataaat gaaaacctta
    19681 gctgtttggc caaggttcat ttcttctatg caagttcttc tcttttctta tctgggttcc
    19741 agatgaagct tgcgataaag ctaaagatga tggttaggat agcgaggata atagcaagga
    19801 tgagggcagg gatgcggata aaccaccaga gtggatttgg ttttttatca ttgtgccatt
    19861 gtttcgtttc ttcgtccaga cgttggaatt ctgtttgaat acgattggcg actgtttcaa
    19921 tgccttcatc attcattttc ttgatatctg agatatcgat tggatttcca aagttcatat
    19981 cgacacgttc acggctaatc aagcccttca aagtcatggg accggtgtag gtaaccggca
    20041 tgatacggac cttggccatt ttggcaatca gtgctgcgcc ccccttgaca tcgtttgagt
    20101 ggcggctacc acttggaaac atgatgagag agcggtcact ttttttgaga acgttgatag
    20161 gatatttgat ggctgaggcg ctgggatttt cacggtcgat gggaaaggcg ccacacatac
    20221 gaacccacca accaaagata cggttggtaa agagttcttt ttttgccata aagatgaact
    20281 gttttggctt ggtcgcaaag gccatataaa caggatccca ccaggtacgg tgaggcgcaa
    20341 ctaaaatata attttcatct tgattaggaa ttttatcagt attatgatag tgagcattgc
    20401 cattgatgga ccataagagc aatacaacta atccacgcaa ataagtataa aacatgcgat
    20461 ctccttcgat tgttttcttg ttattattat accttatcaa aggagggctg gcaaactttt
    20521 cccttgacta gatgcatatt tgggatgaaa ttagaattct gttaaaaaaa atgatataat
    20581 agaatttatg gataaaaata agattatggg attaacccaa agagaagtca aggaaagaca
    20641 ggctgagggt ttggtcaatg actttaccgc atcagccagt accagcactt ggcaaatcgt
    20701 taaacgaaat gtctttaccc tttttaacgc tttgaacttt gccattgctt tggcccttgc
    20761 ctttgtgcag gcttggagca atctggtctt ctttgctgtt atctgcttta acgctttttc
    20821 tgggattgtg accgagctac gagccaaaca catggtggac aagctcaatc tcatgaccaa
    20881 ggaaaaggtc aaaaccatcc gtgatggtca ggaagttgct cttaatcctg aagaattagt
    20941 gctaggagat gtcattcgtt tgtctgcagg agagcagatt cctagtgatg ccttggtttt
    21001 ggaaggcttt gcggaagtca atgaagccat gttaacggga gaaagtgatt tggtgcaaaa
    21061 ggaagttgac ggcttacttt tgtcaggaag tttcctagcc agtgggtcag ttttatctca
    21121 agttcaccat gtcggtgcag acaactatgc tgccaaactc atgcttgagg ctaagaccgt
    21181 taaacccatc aactcccgta tcatgaaatc gctggacaag ttggctggtt ttactgggaa
    21241 gattatcatt ccctttggtc tggctctctt gctggaagcc ttgcttttaa aaggcctgcc
    21301 tctcaagtca tccgttgtaa actcgtcgac agctcttttg ggaatgttgc ctaagggaat
    21361 tgcccttttg accattactt cgctcttgac tgcagtgatt aagttgggct tgaaaaaggt
    21421 cttggtgcag gagatgtact ctgttgagac cttggcgcgc gtggatatgc tctgtctgga
    21481 caagacgggc accatcaccc aaggaaagat gcaggtggag gctgttcttc cactgacgga
    21541 aacttacggt gaagaggcta ttgccagcat cttgactagc tacatggccc atagtgagga
    21601 taagaatcca actgcccaag ccattcgcca gcgttttgtg ggagatgttg cttatcctat
    21661 gatttccaat cttcccttct ccagcgaccg caagtggggg gctatggagt tagaaggctt
    21721 ggggacagtt ttcttagggg cacctgagat gttgctggat tctgaagtcc cagaagccag
    21781 ggaggccttg gagagaggat cacgtgtctt ggtcttagct ctcagtcagg agaaattaga
    21841 ccatcacaaa ccacagaaac catctgatgt tcaggctcta gccttgctgg aaatcttgga
    21901 ccccattcga gagggagcag cagagacgct ggactatctc cgttctcagg aggtgggact
    21961 caagattatc tctggtgaca atccagttac ggtgtccagc attgcccaga aggctggttt
    22021 tgcggactat cacagctatg tagattgctc aaaaatcacc gatgaggaat tgatggccat
    22081 ggcggaggag acagctattt tcggacgtgt ttcccctcat caaaagaaac tcatcatcca
    22141 aacgttgaaa aaagcgggtc atacaacggc tatgacaggg gacggggtta atgatatctt
    22201 ggcccttcgt gaggcggatt gttctatcgt gatggcggag ggagatccag caacccgtca
    22261 gattgccaat ctggttctct tgaactcaga ctttaatgat gttcctgaga ttctcttcga
    22321 gggtcgtcgc gtggtcaata acattgccca catcgccccg attttcttga taaagaccat
    22381 ctattccttc ctgttagcag tcatctgtat tgccagtgct ttactaggtc ggtcagagtg
    22441 gattttgatt ttccccttca ttccgatcca gattaccatg attgaccagt ttgtggaagg
    22501 tttcccacca ttcgttctga cttttgagcg aaatatcaaa cctgttgagc agaatttcct
    22561 cagaaaatcc atgcttcgtg ccctaccaag cgctctcatg gtcgtgttta gcgttctttt
    22621 tgtgaaaatc tttggaacga gtcaaggttg gtctgagtta gaaatctcaa ctctcctcta
    22681 ttatctcttg gggtcaattg gtttcttatc cgtatttaga gcctgcatgc cattcactct
    22741 atggcgagtc ctcttgattg tctggtcagt aggaggcttc ctagccacag ctctcttccc
    22801 aagaatccaa aaactacttg aaatttcaac cttgacagaa caaacgttgc ctgtttatgg
    22861 tgtcatgatg ttggtcttta cagtgatttt catcctgact agtcgctatc aagctagaaa
    22921 ataaagaaag actgcaatct gtggattgca gtttttttag gtacaagatt gccagccgaa
    22981 atgtggtata ataagaggta atagagtttt ggaaagtgag agaagatgat ttcaaagaga
    23041 ttagaattgg tagcttcctt tgtgtcacag ggggctattt tactagatgt gggaagtgac
    23101 catgcttatc tgcctatcga gttggttgag agaggccaaa tcaaaagcgc tattgcaggt
    23161 gaggtggtgg aaggtcccta tcagtctgcg gttaaaaatg ttgaggctca cggcctaaag
    23221 gagaaaatcc aagtccgttt agccaatggc ttggcagctt ttgaagagac tgaccaagtg
    23281 tctgtcatta ccattgctgg catgggtggt cgtttgattg ctaggatttt agaagaaggt
    23341 ttggggaagt tagctaatgt agaacgtttg atcctccagc ccaataatcg tgaagacgac
    23401 ttgcgtatct ggctacagga tcatggattc cagattgtag cagaaagcat cttagaagaa
    23461 gctggaaagt tttatgagat tttggtggtg gaagcaggac aaatgaagct atcagccagt
    23521 gatgttcgct ttggtccctt cttgtccaaa gaagtcagtc cagtatttgt ccaaaaatgg
    23581 caaaaagaag ctgagaagct agagttcgcc ctcggacaaa tcccagaaaa aaatctggaa
    23641 gaacgtcaag ttctagtaga taagattcaa gctatcaagg aggtgctcca tgttagcaag
    23701 tgaagtgatc caagcttatg aagccttttg ccctcaggaa ttttctatgg agggagacag
    23761 ctgtggtctg caaattggca ctttagacaa gggtatccaa agggtcatgg ttgccctcga
    23821 tattcgtgaa gagacggtgg ctgaagccat tgaaaagggt gtagacttga ttatcgtcaa
    23881 gcacgcgcct atctttcgtc ctatcaagga cttgcttgcc agccgtccgc aaaatcagat
    23941 ttacatcgac ctgattaagc atgatatcgc agtttatgtc agccatacca atattgatat
    24001 cgttgaaaat gggctcaatg actggttttg tcagatgcta ggaatcgagg agacgactta
    24061 tctgcaggaa acaggtccag aacgtggaat tggacgtatt gggaatattc agcctcagac
    24121 attttgggaa ttggcccaac aggtcaagca agtctttgac ctagatagcc ttcgaatggt
    24181 gcattatcaa gagaatgatt tgcagaagcc tatttcaaga gtagcaattt gtggtggaag
    24241 cgggcagtct ttctataagg atgctttggc aaagggggca gatgtctata tcactggtga
    24301 catctactac catactgctc aggatatgct gtctgatggc ttgttagcat tggatccagg
    24361 tcactatatc gaagtgcttt ttgtggaaaa aatcgcaaca ctccttactc aatggaaaga
    24421 gaaaaaaggc tgggaactag agattttacc tagtcaagca tcgaccaatc ctttccgtca
    24481 tatctagtta gaaagtgaag acaatgaaaa aagttgccat tattggagca ggaattgtgg
    24541 gagcaacagc tgcctactac ctctcgagag aaagtgacct agaggtgacc gtttttgacc
    24601 atgagcaagg tcaagccacc aaggccgcag caggaattat cagtccttgg ttttccaaac
    24661 gccgtaataa agcctggtac aagatggcgc gcttgggggc tgacttttat gtggatttat
    24721 tagctgattt agagaaatca ggacaaaaaa tcgactttta ccagcgttcg ggagtctttc
    24781 tcttgaaaaa ggatgaatcc aagttggaag aactttatca actggccctc cagcgcagag
    24841 aagaatctcc cttgataggg caattagcca ttctggacca agcttcagct aatgaattat
    24901 tccctggttt gcagggattt gaccgcctgc tctatgcttc tggtggagcg agagtagatg
    24961 gccaactctt ggtaactcgt ctgctagaag ccagtcatgt caagctggtc aaagaaaaag
    25021 tgactctgac actcttatca tcaggctacc agattggcga agaggtgttt gatcaggtta
    25081 ttttggcaac gggagcttgg ttgggggaca tgttagagcc tttaggttat gaagtggatg
    25141 tccgtcctca aaaaggacaa ctacgagatt atcagcttgc ccaagacatg gaagattacc
    25201 ctgttgtcat gccagaaggg gagtgggatt tgattccctt tgcaggtggg aaattatcct
    25261 tgggcgctac ccatgaaaat gacatgggat ttgatttgac ggtagatgaa cccttgctcc
    25321 aacaaatgga ggaggcggcc ttgcctcatt acccagtttt agctagagcg acttcaaggg
    25381 ctgagcgtgt gggaatccgt gcctatacca gtgatttctc tcccttcttt gggcaggtgc
    25441 cagaattggc aggtgtctat gtagccagtg gactaggttc atcaggcctc acaactggtc
    25501 ctatcattgg ttaccatcta gcccaactga tccaagacaa ggagttgacc ttggaccctc
    25561 taaattaccc aattgaaaac tatgtcaaac gagtaaaaag cgaataatac tcaatgaaaa
    25621 tcaaagaaca aactaggaaa ctagccgcgg attactcaaa gtactgcttt gaggttgtgg
    25681 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    25741 tcagctcaaa acactgtttt gaggttgtag atagaactga cgaagtcagt aaccataccc
    25801 atggcaaggc gacgttgacg tggtttgaat tggattttcg aagagtataa gcattttact
    25861 gaaattttat caggtagttt aggatggcaa atgacattcc ctgtcaaaaa tggtaaaata
    25921 agaaaaaata atctgagaat cgaggaaaaa agatgcaaga aaagattttg gtaactggtg
    25981 gtgccggttt tattggaacc cacactgtta ttgaattgat ccaagcaggc catcaagttg
    26041 ttgtggtgga taatcttgtc aatagcaatc gtaagagttt agaagttgtt gaaagaatca
    26101 caggagttga gattcctttc tatgaggcag atattcgtga cacagatacc ctcagagata
    26161 ttttcaagca ggaagaaccg actggtatca ttcactttgc tggtttgaag gctgttggcg
    26221 aatcaacacg tatccctctt gcctactatg acaacaatat cgctggaact gtcagccttt
    26281 tgaaagccat ggaagaaaac aactgtaaaa acatcatctt cagttcttct gcgacagttt
    26341 acggggatcc gcacacagtg cccatcttgg aagatttccc actttcagtg accaacccat
    26401 acggtcgtac taagctcatg ctagaggaaa ttttgaccga tatttacaaa gcagactcag
    26461 aatggaatgt tgtcttgctt cgttacttta acccaatcgg agcccatgag agtggtgatt
    26521 tgggagaaaa tccaaacggt attccaaaca atctcttgcc atatgtgact caagtagccg
    26581 ttggaaaatt agagcaagtg caagtgtttg gagacgatta cgatacggaa gatggaacag
    26641 gtgttcgtga ctatatccac gttgtcgatt tggctaaggg tcacgttgca gctttgaaaa
    26701 aaatccaaaa aggttcagga ctaaacgttt ataaccttgg aactggtaaa ggttactcag
    26761 ttcttgaaat tatccaaaac atggaaaaag cggtgggacg tcctattcct taccgcatcg
    26821 tagaacgtcg cccaggtgat atcgctgcct gctactcaga cccagcaaaa gctaaagcag
    26881 aactcggttg ggaagcagaa ctcgacatca cccaaatgtg tgaagacgca tggcgttggc
    26941 aaagcaagca tccaaatgga tttgaagact aagatgatga tttcaatcat cgtcccttgt
    27001 ttaaacgaag aggaagtact tcctcttttt tatcaggctc tggaagcttt acttccagat
    27061 ttggaaacag aaatcgagta tgtctttgtc gatgatggat caagtgatgg gaccttggaa
    27121 ctcttaaagg cctatcggga gcaaaatccg gcagtccatt atatttcttt ctctcgaaat
    27181 tttggcaaag aagcagccct ttatgcaggc ttgcaatatg cgacaggaga tttggtggtg
    27241 gtgatggatg cagacctcca agatcctcct agtatgttgt ttgagatgaa aaatgtacta
    27301 gacaaaaatg tagacttgga ctgcgttggg acacggagaa ctagtcggga gggagaaccc
    27361 ttctttcgca gtttctgtgc tgttctcttt tatcgcctca tgcaaaaaat cagcccagta
    27421 gctctgccgt cgggtgtccg tgattttcgt atgatgagaa ggtctgtagt cgatgccatt
    27481 ttaagcttga ccgagtccaa tcgtttttca aaggggctct tcgcctgggt gggtttcaaa
    27541 acctactatt tggactatcc aaatgtcgaa aggcaggctg gcaagacaag ttggagtttt
    27601 aggcaactct ttttctactc cattgaaggg attattaatt tttcagattt tcccttgatt
    27661 atagcctttg tagctggtct cctatcttgt tttctttctc tgctgatgac cttttttgtt
    27721 gtggttcgga ccctcatttt gggcaatccg acatctggtt ggacctctct gatggctgtt
    27781 attctctttc ttggaggcat tcaactcttg accattggga ttctcggcaa gtatatcagt
    27841 aagatttatt tagagactaa aaaaagacca ctttatctta tcaaagaaaa aagtgacctt
    27901 cctgatttta cagaaaaaaa taaagtgaaa agactataat tttacatgga aatgtgctaa
    27961 actagaggga gtggattatc gccattgatt taggcttcct ggtttccaat cagggcgcga
    28021 gttgggcaat ttttaacagc ctctaagaca tcctgactag gagaaatttc tttttccagt
    28081 tggtcagggt catcgtaaaa acgcacgatt ccattatcgt ggtaatcaaa taaatcagaa
    28141 taagtttggc aaagcccaca ggcgatacat cgttcaggta taagtgtgat tttcatgttc
    28201 atatttatat tgtaataaga aaagtaaaaa aaaacaagga gtaaggtatg gcaaaagaac
    28261 cgtggcaaga agatatctat gatcaagaag aatcaagagc agagcgtcgg catcgaaacc
    28321 acggaggggc tgataggatg gctaatcgta ttttgacgat cctagctagt attttctttg
    28381 taattgtggt ggtgatggtc atcgttctca tctatctatc atcggggggg agtaatcgca
    28441 cagcagcctt aaaagacttt catgattctg atgcaagtgt agtacaaatc tcatcttcaa
    28501 gcagttctca gcctgagcag agttcagagc cagaatctac ttctagtagt tcagaagaag
    28561 ctgctaatcc tgaaggaacg attaaagttc tcgcaggaga aggggaagca gctattgccg
    28621 ctcgtgcagg aatctccatt gctcagttag aggccttgaa tcctgggcac atggctacag
    28681 gatcttggtt tgctaatcca ggtgatgtta taaaaataaa ataggagccg atatgaaaac
    28741 aattcaaatt gctattgatg gtcctgcttc cagcggtaag agtacggtcg caaagattat
    28801 tgctaaggat tttggattca cctaccttga tacaggagct atgtatcgtg cagcgaccta
    28861 tatggctctt aagaaccaat tagtagttga agaagtcgaa gcccttctag ccttgttgga
    28921 ccagcatcca atcagctttg gacgttcaga aactggagac cagcttgttt ttgtaggaga
    28981 tgtggatatt acccatccta tccgtgaaaa tgaagtgacc aatcatgttt ctgctattgc
    29041 agcaattcct gaagtgcgtg agaaactggt ttctctccaa caagaaattg cccagcaagg
    29101 cggaattgtc atggatggtc gcgatattgg aactgttgta ttgccacaag cagaattgaa
    29161 aattttccta gtagcttctg ttgatgagag agcagagcgt cgttacaagg aaaatattgc
    29221 caagggaatt gaaacagacc ttgaaaccct aaaaaaggaa attgctgcgc gtgactacaa
    29281 ggatagtcat cgtgagactt ctcctctcaa acaagcagag gatgctgtct accttgatac
    29341 aactggtttg aacattcaag aagtagttga aaaaatcaaa gcagaagctg aaaaaagaat
    29401 gtaaatgtag aaaagccgat agattgatat cggttttttc taaatttgtc aaaatgctga
    29461 ttttagggta taatagttgc tgttcgagaa attttgattt tcaaagaata gtgaatgatg
    29521 ataaggagaa atcatgaaca atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta
    29581 cgaagacggt gccctactgg tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt
    29641 tgcagaagta gaagaaggtc ttgtcgctat cgatgccaac ggaaataaat tggctgatgg
    29701 tgatacagta actctcatca aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca
    29761 agggacgcgc gtgaaaaata tccgcatcgt agaaggcgac cacaatatcg actgtaagat
    29821 tgatggtttt ggtgccatga aacttaaatc agagtttgtg aggaagattt aagcatgtca
    29881 aaacactata aacttgtatt ttatagccgt atcttcttgt ttctagcggc ttttacggga
    29941 gtttatcttg aaattactaa gcatggtggt tttgggatgc ttctctatta cacggttctg
    30001 tccaacctct tggtaactat ttttaccctt tatcttctaa aggttatgag ccgtgtaggt
    30061 gaaaattggc aaagaccaag tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg
    30121 attacctgtg tgatttacca tttcctcttg gcgcccattg cgactaattt ctatacccta
    30181 gaaaatttcc tttgccacta tatcgttccc atctggtttt tagcggatac cctctttttt
    30241 gacaaacagg gtcaatacaa gatttgggat ccagcagtgt ggaccatttt accctttctg
    30301 tatatgatgt ttgctctttt taatggcttg gttctaaaac tcaatattcc aaatgccaag
    30361 gataatcctt tcccttactt ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag
    30421 tggtgtctga ttatctttgt tgcctatatg gtagcaggat ttattttcta ctttatcaag
    30481 caaatcaaga gaaagtcatc ctaatactct tcgaaaatct cttcaaacca cgtcagtttc
    30541 catctgcaac ctcaaaacac tgttttgaac aacctgcggc tagcttccta gtttgctctt
    30601 tgattttcat tgagtataag atacaaggga ttcattttcg aatttaagaa ggagtctaca
    30661 aaccaatgag gcttcttctt ttcttgctta tttgataact atcaaaaaag tagaagatta
    30721 agagaaatat agaaagagat ttcatgaaac aatttttaga acgggccagc attttggctc
    30781 tctccctcgt tttgattacc tccttttcca tttcgagtgc tctaccagcc atgtttgact
    30841 attatcaggg ttattctaag gaacaaattg agctcttggt gagcttgcct tcctttggaa
    30901 tcatgatgat gttactgcta aatggtttct tagaaaaaat atttcctgag cgcttacaga
    30961 ttagtttggg cttgctgatt ttatcattga gcggtacagc tcccttctgg taccaagcct
    31021 atccctttgt ctttggaaca cggcttctct ttggtttggg tcttgggatg atcaatgcca
    31081 aggccatttc tattatcagt gaacgctacc aaggaaaaag gcgaattcag atgttagggc
    31141 tacgcgcttc tgcagaggtc gttggagctt ctctcattac cttggccgtc ggtcagttgt
    31201 tggcctttgg ttggacagct atctttctag cctatagtgc tggatttttg gtgctgcccc
    31261 tttatctgct ctttgtccct tatggaaaat caaagaaaga agtcaagaaa agagcgaagg
    31321 aagcaagtcg tttaactcga gaaatgaaag gcttgatttt taccttagct atcgaagcgg
    31381 cagttgtagt ttgtaccaat acagctatta ccatccgtat tccaagtttg atggtggaaa
    31441 gaggattggg ggatgcccag ttatctagtt ttgttcttag tatcatgcag ttgatcggga
    31501 ttgtggctgg ggtgagtttt tctttcttga tttctatctt taaagagaaa ctgctcctct
    31561 ggtctggtat tacctttggc ttggggcaaa ttgtgattgc cttgtcttca tccttgtggg
    31621 tggtagtagc aggaagtgtt ctggctggat ttgcctatag tgtagtcttg acgacggtct
    31681 ttcaacttgt ctctgaacga attccagcta aactcctcaa tcaagcaact tcatttgctg
    31741 tattaggctg tagtttcgga gcctttacga ccccatttgt tctaggtgca attggcttac
    31801 taactcacaa tgggatgttg gtctttagta tcttaggagg ttggttgatt gtaatctcta
    31861 tctttgtcat gtacctactt cagaagagag cttaggattg attcctaagt ttttcttttg
    31921 atactcaatg aaaatcaaag agcatagttg attgagtttg gaatagtacg ctgtagttgc
    31981 taaaatattt ctagaaatta atttgacttt tctaatagag ttattcatat cttatttcaa
    32041 tctactatag aaagctagcc gcaggttgct caaaatagtg ttttgaggtt gcagatggaa
    32101 actgacgtgg tttgaagaga ttttcgaaga gtatgagatt tttataccca tacaatattt
    32161 gttttaggtc cttgtttaca gactaatttc ttgataaaat agaggttatg acgagatata
    32221 aagcaactat ttcctatgat ggttatgcct ttgctggctt tcagcgccag tctcatgcgc
    32281 gtagcgttca ggaagaaatt gaaaaaacct tgaccagatt aaataaaggg caaaccatta
    32341 ctgttcacgg tgctggtagg acagatagtg gggttcatgc cctgggacag gtcattcatt
    32401 ttgacctgcc ttatcagatg gatgaggaga aactccgttt tgccttggat acccagtctc
    32461 ctgaagatat tgatgtgatt tcgattgagc ttgtggcaga tgattttcat tgccgttatg
    32521 ccaaacatag caagacctat gagtttattt tggatagagg acgtcccaaa aatcctatgc
    32581 gccgtcacta tgccacccac tttccctacc cactcgatgt ggaacgaatg cagattgcaa
    32641 tcaaaaagct agagggaacc catgatttta ccggttttac agcctctggg actagtgtag
    32701 aggataaggt tcgcaccatc acagaagcta gtttaatagt cgatgagaca ggacaatttt
    32761 tgacctttac cttttcagga aatggtttct tgtataaaca gattcgcaat atggtgggga
    32821 ctcttctcaa aatcggtaac aaccgcatgc cagtagagca gattgatctc atcttggaga
    32881 agaaggacag gcaacttgca ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga
    32941 ttcgttatga agaataatcg tattttagca ctttctggaa atgatatttt tagtggtggt
    33001 ggactgtcag ctgatttggc tacctatacc ttgaacggct tgcatgggtt tgtagcagtg
    33061 acttgtttga cagccttgac agaaaaagga tttgaagtct ttccaactga tgataccatt
    33121 tttcaacatg aattagatag cttgcgtgat gtggaatttg ggggaattaa gattggtctt
    33181 ctccctactg tcagtgtggc tgagaaggcc ttggacttta tcaaacaacg cccaggagta
    33241 cctgtggtgt tggatcctgt cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag
    33301 ctctgccaag agttgattcg ctttttccct tatgtcagtg tgattacgcc taatctccca
    33361 gaagcagaat tattatccgg tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg
    33421 cagaaattgc atgatttagg agcgccagca gtcattatca agggaggcaa tcgtcttagt
    33481 caggacaagg ctgtggatgt cttttatgat ggacagacct ttactatcct agaaaatcca
    33541 gttatccaag gccaaaatgc tggtgcaggt tgtacctttg cctctagcat tgccagtcac
    33601 ttgattaaag gtgataaact tttgccagca gtagaaagct ctaaggcttt cgtttatcgt
    33661 gctattgcac aagcagatca gtatggagta agacaatatg aagcaaacaa aaacaactaa
    33721 aatcgccctt gtatccctat taaccgccct ttctgtggtt ctaggttatt tcttaaaaat
    33781 cccaacacct acaggaattc taactctttt agatgctggt gtcttctttg cggcctttta
    33841 ctttggtagt cgtgaaggag cggtagtcgg aggactagca agtttcttga ttgacctctt
    33901 atcaggctac cctcagtgga tgttctttag cttggtcaac catggcttgc agggattttt
    33961 cgcaggattt aaaggaaaaa gtcagtggtt aggccttatt ttagcaacta ttgccatggt
    34021 aggaggctac gccttgggtt ctactttgat gaatggctgg gcagcagccc tcccagaaat
    34081 tctaccaaat ttcatgcaaa atatggtagg gatgattgta ggatttattc ttagtcaaag
    34141 tatcaagaag attaagtaat actcttcgaa aatctcttca aaccacgtca gtttccatct
    34201 gcaacctcaa aacactgttt tgagcagcct gcggctagct ttctagtctg attttcattg
    34261 agcataaaga ggttgagtaa aaagtctttc aaataagaaa aacgcatagt ataggatgtt
    34321 gaaatgatga actgcccccc aaaagttaga cagaaaaaat ctaacttttg gggtgtttta
    34381 ttatgaaact aacttatgat gataaagttc agatctatga acttagaaaa caaggatata
    34441 gcttagagaa gctttcaaat aaatttggga taaacaattc taatcttagg tacatgatta
    34501 aattgattga tcgttacgga atagagttcg tcaaaaaagg aaaaaatcgt tactattctc
    34561 ctgtttaaaa caagaaatga ttaataaagt ctgacatgaa ggctagacta aagatagagt
    34621 ttctcttgaa tacggtctcc caagtcgtac gatacttctt aactggctag cacaatacag
    34681 aaaaaaacgg gtatactatt gttgagaaaa caagagggag agtacctaaa atgggacgta
    34741 agccaaaaaa gagacctgaa tagaggacag aattagaaca tcttcaagca gaaaatgagt
    34801 acctgagagc ggagaa
//
LOCUS       DAVHSH010000015        34122 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000015 DAVHSH010000000
VERSION     DAVHSH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.015"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            106..288
                     /locus_tag="VVR08_000885"
     CDS             106..288
                     /locus_tag="VVR08_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6074827.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            298..660
                     /locus_tag="VVR08_000886"
     CDS             298..660
                     /locus_tag="VVR08_000886"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6074828.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKTGVKSK"
     gene            657..1847
                     /locus_tag="VVR08_000887"
     CDS             657..1847
                     /locus_tag="VVR08_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6074829.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKTIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(1923..3485)
                     /gene="guaA"
                     /locus_tag="VVR08_000888"
     CDS             complement(1923..3485)
                     /gene="guaA"
                     /locus_tag="VVR08_000888"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU6074830.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3627..4325
                     /locus_tag="VVR08_000889"
     CDS             3627..4325
                     /locus_tag="VVR08_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6074831.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4368..5264)
                     /locus_tag="VVR08_000890"
     CDS             complement(4368..5264)
                     /locus_tag="VVR08_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6074832.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATTKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIILAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5273..6208)
                     /locus_tag="VVR08_000891"
     CDS             complement(5273..6208)
                     /locus_tag="VVR08_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU6074833.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKVGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6205..6930)
                     /locus_tag="VVR08_000892"
     CDS             complement(6205..6930)
                     /locus_tag="VVR08_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU6074834.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7014..7649)
                     /locus_tag="VVR08_000893"
     CDS             complement(7014..7649)
                     /locus_tag="VVR08_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU6074835.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7651..8478)
                     /locus_tag="VVR08_000894"
     CDS             complement(7651..8478)
                     /locus_tag="VVR08_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6074836.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQAI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8500..8836)
                     /locus_tag="VVR08_000895"
                     /pseudo
     CDS             complement(8500..8836)
                     /locus_tag="VVR08_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(8837..9553)
                     /locus_tag="VVR08_000896"
     CDS             complement(8837..9553)
                     /locus_tag="VVR08_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU6074837.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGYP
                     HVVEPSETVEKDGDKKLIVY"
     gene            10066..10677
                     /locus_tag="VVR08_000897"
     CDS             10066..10677
                     /locus_tag="VVR08_000897"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6074838.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEKVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10722..11450
                     /gene="rlmB"
                     /locus_tag="VVR08_000898"
     CDS             10722..11450
                     /gene="rlmB"
                     /locus_tag="VVR08_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU6074839.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11489..12400)
                     /gene="trxB"
                     /locus_tag="VVR08_000899"
     CDS             complement(11489..12400)
                     /gene="trxB"
                     /locus_tag="VVR08_000899"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU6074840.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12466..12690)
                     /locus_tag="VVR08_000900"
     CDS             complement(12466..12690)
                     /locus_tag="VVR08_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU6074841.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12768..13511)
                     /locus_tag="VVR08_000901"
     CDS             complement(12768..13511)
                     /locus_tag="VVR08_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6074842.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13511..14311)
                     /locus_tag="VVR08_000902"
     CDS             complement(13511..14311)
                     /locus_tag="VVR08_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6074843.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14469..14825)
                     /locus_tag="VVR08_000903"
     CDS             complement(14469..14825)
                     /locus_tag="VVR08_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6074844.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14838..15350)
                     /locus_tag="VVR08_000904"
     CDS             complement(14838..15350)
                     /locus_tag="VVR08_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU6074845.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15350..15844)
                     /locus_tag="VVR08_000905"
     CDS             complement(15350..15844)
                     /locus_tag="VVR08_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074846.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGKRLAYQ
                     KLKK"
     gene            15979..16425
                     /locus_tag="VVR08_000906"
     CDS             15979..16425
                     /locus_tag="VVR08_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU6074847.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16422..17069
                     /locus_tag="VVR08_000907"
     CDS             16422..17069
                     /locus_tag="VVR08_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU6074848.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17090..17671)
                     /gene="pdxT"
                     /locus_tag="VVR08_000908"
     CDS             complement(17090..17671)
                     /gene="pdxT"
                     /locus_tag="VVR08_000908"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU6074849.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREGILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17672..18547)
                     /gene="pdxS"
                     /locus_tag="VVR08_000909"
     CDS             complement(17672..18547)
                     /gene="pdxS"
                     /locus_tag="VVR08_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU6074850.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18699..20078)
                     /locus_tag="VVR08_000910"
     CDS             complement(18699..20078)
                     /locus_tag="VVR08_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU6074851.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20372..21295
                     /locus_tag="VVR08_000911"
     CDS             20372..21295
                     /locus_tag="VVR08_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU6074852.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVENLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21355..21960
                     /locus_tag="VVR08_000912"
     CDS             21355..21960
                     /locus_tag="VVR08_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6074853.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            21979..23223
                     /locus_tag="VVR08_000913"
     CDS             21979..23223
                     /locus_tag="VVR08_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6074854.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23340..23597)
                     /locus_tag="VVR08_000914"
     CDS             complement(23340..23597)
                     /locus_tag="VVR08_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU6074855.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23639..25675)
                     /locus_tag="VVR08_000915"
     CDS             complement(23639..25675)
                     /locus_tag="VVR08_000915"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU6074856.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(25935..26852)
                     /gene="glyQ"
                     /locus_tag="VVR08_000916"
     CDS             complement(25935..26852)
                     /gene="glyQ"
                     /locus_tag="VVR08_000916"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU6074857.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27047..27808)
                     /locus_tag="VVR08_000917"
     CDS             complement(27047..27808)
                     /locus_tag="VVR08_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6074858.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDLNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28081..28923)
                     /locus_tag="VVR08_000918"
     CDS             complement(28081..28923)
                     /locus_tag="VVR08_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU6074859.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSITISRIQANLDCFGIELSHKERETLKTIAVQLGAPRVD
                     DVDF"
     gene            complement(29037..30428)
                     /locus_tag="VVR08_000919"
     CDS             complement(29037..30428)
                     /locus_tag="VVR08_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU6074860.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(30663..31040)
                     /locus_tag="VVR08_000920"
     CDS             complement(30663..31040)
                     /locus_tag="VVR08_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6074861.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31255..32232
                     /locus_tag="VVR08_000921"
     CDS             31255..32232
                     /locus_tag="VVR08_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6074862.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            32229..33311
                     /locus_tag="VVR08_000922"
     CDS             32229..33311
                     /locus_tag="VVR08_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6074863.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33375..34122)
                     /locus_tag="VVR08_000923"
                     /pseudo
     CDS             complement(33375..34122)
                     /locus_tag="VVR08_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10327 a         7484 c         6105 g        10206 t
ORIGIN      
        1 ataacaagag gatagaaatg accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa
       61 tattctgata acttaaacat caaagttcaa gagagagttc gtgaaatggc aaatgataat
      121 aagagccatt atttgatata cagagtttta ggtatttcat ttgaagaagg agaaaatatc
      181 gatttgtatc aaaataaagg tcgtttttta tacaaatatg ctggttcatt tttagaagaa
      241 gctgcagtac tatcctttaa cgaaaaattt ggtacagaaa atacttaaaa agttaacatt
      301 cctaattctg aaagtacaaa acctaagact tttgaaattg attgtttagt cggagaaaaa
      361 cacgcatacg aaataaaatg gtgggatgca actacagatg gagaccatat aactaaagaa
      421 cacactagaa taaaagttat tcataacaaa ggatatatac caattcggtt aatgttctac
      481 tatccaaata gaactcaagc tataaaaatt cagcaaactt tagaaacatt gtataacggt
      541 attggaggga aatattatgg agattctgcc tgggaacatt taagagcagt gaccggtatt
      601 gatttactta gtattctaac agatattgca aataaaaaaa caggggtaaa atcaaaatga
      661 cagtattaaa aggagataac ttagaaatat taaaaactat tgaatcctca agtattgatt
      721 taatctatat ggaccctcct ttctttacac agaaaaccca aaaattatct aataacaaaa
      781 atattatgta ttcattcgaa gatacgtgga cttcgattga ggattacaaa gaatttttgt
      841 ctgtaagatt agaagaatgc aaaagagtgc taaaaaatag tggcagtatt ttcgttcatt
      901 gtgataaaat tgcaaatcat catattagat taattttaga taatatcttt ggagcagata
      961 tgtttcaaag cgaaattata tggaactata agcggtggtc taattcaaaa aagggattat
     1021 tgaacaatca tcaaaacatt tacttttatt caaagtcaaa agattttaaa tttaatacaa
     1081 tttttacaga gtattcttct actacaaata tcgaccaaat actagtggaa cgaaaacgag
     1141 atggaaactc taaaactata tataaagttg ataataatgg taactatatt ctagcaaaag
     1201 agaaaaatgg agttcccctt tcagatgttt ggaatatacc atttcttaat ccaaaagcta
     1261 aagaaagagt aggttatcct acacaaaaac ctattctgtt attagaacaa attataaaga
     1321 ttgctactga taaaaatgat atagttttag acccgttctg tggaagtgga actactttag
     1381 tagcctccaa gattttgaat agaaattata tggggattga tttatctgag gaagctatca
     1441 atataactca gcaacgtctg gaaaatgtta taaaaacaag ttcaaattta ttgaataaag
     1501 gaatcgaagc atatagaacc aaaactgagg aagaggaaaa cattcttaaa ttattacagg
     1561 caaaaattgt tcaaagaaat aaaggaattg atggtttttt acctaaacat tttcaaaaaa
     1621 aaacgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt atctctttat
     1681 tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa actcattcag
     1741 ataatttatt atttgatttt gatacgatcc ctgaaaatat aatagtagtt gaccattttg
     1801 aacttacaat cgaaaaatgg ttaagtaaaa gtcaacagtt actatagttt gcaaattatt
     1861 tacagaaaga acaaaaaatg ctctgaaaca ctgatttcaa ggcatttttt gttagtttaa
     1921 aattactccc actcaactgt tgcaggtggt ttacttgtaa tatcgtagac gatacggtta
     1981 acatgatcca cttcatttac gatacgtact gagatttttt gaagtacttc ccatggaatt
     2041 ttggcaaaat cagcagtcat accatcgata gaagtgatag cacggattgc aatcgtgtag
     2101 tcatacgtac gaccgtcacc cataacaccg actgaacgaa cgcctgtgtt aacagtgaag
     2161 tattgccaaa tatcgcggtc aagtccagct ttagcgattt cttcacgaag aatagcgtct
     2221 gattcacgaa cggtttcaag tttctcttca gtgatttcac ccatgacacg gatagcaagt
     2281 cctggtcctg ggaatggttg gcgccatacg atatggtctg gcataccaag ctctgtacca
     2341 agagcacgaa cttcatcctt gtaaagagta ttgagtggtt caatcaattc aaactgcata
     2401 tcttctggaa gaccacccac gttgtggtgt gacttgatag tttgagctgt atccgtacca
     2461 gactcgataa catctgtata taaagtacct tgagcaagga atttcacatc tttgagcttg
     2521 cttgcttcgt catcgaatac atagacaaac tcgttaccga tgattttacg tttttgttca
     2581 gggtcagaaa cgccagcaag tttgtcaagg aaacgtttag cagcgtctgc tttgacgata
     2641 ttcaaaccaa acttaccacc gagcatgtcc ataacttgat cagcttcgcc tttacgaaga
     2701 agaccgtggt ctacgaagat acagatcaat tgatcgccaa tcgctttttg gagaagaacc
     2761 ccaacgacag atgagtcaac accacctgat agaccaagaa ggacacgttt atcaccgacg
     2821 gtttcacgaa tttttttgat ctgcatgtca atgaaattat ccattgacca gtcaccttta
     2881 gccttacaaa tgttaagggc aaagttacga aggatatcat ttccgtatac agaatgacga
     2941 acttctgggt ggaattggat accgtaaatg tgtttatctg ggttttcgat ggctgcgtat
     3001 gggcagtcag ctgatgtacc tgtacgaaca aagtcagcag gaatctcagt aaccgcatca
     3061 ccatggctca tcaaaacagt ctgttcatca ggtgttgatt caaaaagcgc tgatggtgtg
     3121 tgagttaggg ttgattgacc gtattcacga tttccagcat cacctgcagg aacaactttt
     3181 cctccaagtt tatgggtcaa taactgcata ccataacaga ttcccaaaat tggaattccg
     3241 agttcgaaga tttctgggtc aatatcaaat gaaccatctt catatacaga atttggacca
     3301 cctgatagaa taattcctac aggattgact tcacgaactt cagcagctga aattttatgg
     3361 ctttttagtt ctgaaaaaac accaatctca cggatacggc gtgaaatcag ctggttgtac
     3421 tggctaccat agtccaatac gatgattttt tctacatctt gcaaatcagt tgaaatgttg
     3481 ctcatctttt tcctttctca aaagaaatat cttttctcaa tattctatca caaataaggg
     3541 cgaattacca actaaacaag gcgaagtttg actttttcta gtttattggg gtacaataga
     3601 gaaaagatag aaatgaagtg aaaaatatgc tacctgctta tatgaaaatc catgatcaga
     3661 taaaaaagga tattgacgag caccgttggg ctattggtga gaggcttccc agtgaaagag
     3721 atttagctga gcagtttgcg gtcagtcgca tgaccctccg ccaagccgta tctctattag
     3781 tcgaagaagg cgtcttagag cgccgtgtag gaagcggcac ctttgtttcc agtactcgag
     3841 tacaagaaaa gatgcgaggg acaaccagtt ttactgaaat tgtcaaatcc caaggtaaag
     3901 ttccctctag ccagctcatt tcctacaaaa aaaccattcc caatgagcaa gaagttgcca
     3961 agctaggaat ttttccaacg gacaatatta tccgaatgga gcgggtccgc tatgccgacc
     4021 aagttcccct agtttatgaa gttgcttcta ttcctgaaaa attcattaag gactttaaaa
     4081 aagaagaaat caccagtcat ttcttccaaa ccttgcaaaa acatggctat cgtatcggta
     4141 aatcccaaca gaccatctat gctcgccttg ctaaagaaaa gattgcccac tatttggaag
     4201 ttgaaaaagg acatgctatt cttggattga cccagatttc ctacctagaa gatggtactg
     4261 cttttgaata cgtaaaaagt caatatgtag gcgaacgctt tgaattttat cttgaaaata
     4321 attagattac cacgcaaaaa ctctctgtca cggacaaaga gtctttttta tttttctaag
     4381 aataaatctt tcaaagaaat caaagttaca gcaaacaata tcattgccat accaagaaaa
     4441 tcaatgggat aaaattgttc attcattatt aagaaggcaa agaaaatcgc cgatattggc
     4501 tcaattgaag ccaacaagct tgacttgacc ggtcctatca gactggctcc tttaaggaaa
     4561 gctgtatagg caaagacagt cccgataagg ataatgcctg caaacgcaag gagaaaatca
     4621 agactagtcg ggatatcggc ctgtagaacc cctgtaaaag gaagggcgac caaacctgct
     4681 atgaccattc ccacaccaat gaccaagctg ctcccccact ttttaatcaa ggctatgggt
     4741 aaaatgatat acagagcata agtcaaggca gaaaagagac cccagaacag gccagcaggt
     4801 gtcatggata actggtccaa ctgcccatgt gttgcgatca ggaaggttcc tccgatggcc
     4861 aatatgatgg aaactatctc tcccagtgtc ggtgccaccc tatccttgat acagctataa
     4921 attaaaattc cgacaggaca aacatactga agcaccgtcg ctgttcccgc attggtctcc
     4981 tgaatagcag acagataggc gaattggttg agaaaaagac caatcagagc aaaaataaga
     5041 agagacagca aactctttct atcctttaaa aagaccagta ttttatcctt tgtagtagca
     5101 taagccaaga gcatgagaat tccaccagcg attaaaagac gcaagttggt caagaccaga
     5161 gccgaaattc cgtgtgccat taggtattgg ccactcgttc ctgacaaccc ccaagcaata
     5221 ccagccacaa ctgttagtaa agtccctttt aaactatttg acatgtctct ccttactctt
     5281 ctttgcgaat caagttcatc acttgattgc ggtctaatat ccattgagct ctctcgtcct
     5341 tttcataggt acgattcgat aggaaaatag tggcttcttg cttctgacga ttccacatga
     5401 taaaggtacc tgtatagccc gtatggtcta gccaatctcc ttccaaattc catgctaaag
     5461 aacgttcctt gtcatccaaa ggagaaaaat tttgatttaa gtctcttgca aaatcatctg
     5521 ctaaatagtg ttctaaaaag atttgtaaat cctttatagt cgaaaataaa ccagcactcc
     5581 cagcatgtct acccaggaga cgagccttgg gatcatgcac tatgcctgcc tctacacctc
     5641 taactgttgg aacagcaagc tcaactggcc caaccttggt ttccgtcatt ccccaaggtt
     5701 tccagacttg atcctttaaa atcacatcca aatcttgatt aaaaattctt tccaaaataa
     5761 agcccaacaa caaaaaatgg acatccgaat aaagaaaggc tggctgactt cgtctgttga
     5821 gatgaaacat cgcttccttt aattcagggg ctgttaaaag atcacgatta ggaataaaag
     5881 gatcaaggtc tgttgcatga gtcaagagct ggcgaatagt gatgtctgga taatcactct
     5941 caggtaaaaa atctattacc agtctatcaa tatctaattg acctatttcc cacaagaagg
     6001 tacaaactgt gccaacccca acaaccttgc tgacactagc taggtcataa actagtcctg
     6061 cctcagtctg caagccatgc tctggggcac tctggcctaa atagaactct gtccattgat
     6121 tgtccttaaa atacgcaaaa gaggctccgg gataaattcc tgcctcgatt tgttcttcta
     6181 tttttttaat aatcttggtc cacttcatac ttcttcaaac cacaattcaa cattatttct
     6241 atctttacca aggaagaatt tttcagactt aggaataaaa tattcagtag actcaaactt
     6301 ctggcgaaga cttgctatgt ctaattcatt gaccaagaac ttgagcatag ataagtccca
     6361 ggtaaccgta ttgtccacag tcaaatcctg cccctgagct ggaataaaat caagggatgc
     6421 cccaatttca gatgattcca agaaactttc gatatcagtt gggagatgta attccataga
     6481 aatctcaaat ttacttaaag aaattgatgc caaatctgtt tgaaattcag gcttttctcc
     6541 tacttctact agacttgctc tgtcatcttc cgcatgaatc aaaatcaaat catcttctgg
     6601 tgagaaaatt tcaaaagcgt agccattttg acctttatat aatcgatgaa tcgaatctgt
     6661 tttagataag attccttcaa tttctaaggg attttccacc ttgacaatca atctagctag
     6721 tttttttctt ccctctacct tacgagtacg catactggga gcttcttcta aaaccagctt
     6781 ttcaagaccc gtttggtcac ctagtgacag aaaggccgat tcttctaaca gggccttcat
     6841 tccaagggtt tcaatataaa atgtttcatt taattttcta ttattagctt ttaaagtagg
     6901 aataatccgt acaatctgat ttacattcat aaattcctcc gtcacttttt attttaaagg
     6961 attttagaat tttttacaag atattatgct caaatttaac attatttagc tatttagtaa
     7021 agatagtctt tcaaggcttt tgacaaagcc tgataaccag caatactgag gtgcagtcca
     7081 tcagttgtat attctttttt gagttggcct gcttgatctg tcaaacaatc aaatactggc
     7141 acaaattcca cctgcatata ggcagatgca agctcttgat aggcttgatt ccaattctga
     7201 attttttcat tcgagcggat atagactgcc tgctggtact tctctccctc attgacaggc
     7261 aaaatggaaa gcaatttaat ctctgtcaat ggataatcgc gagcaacgga ttgaatgata
     7321 gcttcgagat tattgagagc ctcattcaca ggaacatcct ttccgatatc atttgtccca
     7381 atcagaagaa aaattttatc tactgctcca ccatatagat gagcatcaag gttctctagt
     7441 aacagtcctg tctgatagcc acgaattcct cgattgacaa tcgtctttga agtcccaaat
     7501 agctcctgta gaggataata ctcgacaatg gaatccccaa taaaaagaat gtttggttct
     7561 acaacagaaa tgtgatttag gtgacgatac ttggtttgaa ttttttcttg ttcctttagg
     7621 agccaatttt ctaataactg tactgccact tcattctcct ttttctaacc agttttccaa
     7681 gacttgataa actcctcctt ggctgttggc tggtgctaga gcagtcgcca cagctttggc
     7741 tttctcatca gcattttcca tcgcataggc aattccagcc atttcaagca tttcaacatc
     7801 attttcacta tcaccaaaag ccatgattgc ttgggatttc aagtcccagc gcttgagtaa
     7861 ttcctccaag ccccatgctt tatgaatccc agcttggagg atatcaatgc aaccatagcc
     7921 actggataca gctcggacac ggccatcaaa gagagtattg atttcttcca aaaccgaact
     7981 caaacgttcc tcaccaacaa ccatgctcat cttgagcaca ccaccaaaga ggtcagatgt
     8041 taattcatcc acaaattgca tccgttggta gaatttttca atcatttctg gagtcataaa
     8101 actttcaaga tctgtaaaaa tcgtaccttc cttgacaaaa tcacccttca tccccgttac
     8161 aacaaactgg tcctgacacg ctcgaccctt gaaatgagcc aaagccttgt tgacaatggc
     8221 gtcatcccat gtctgagcct gaatcaattc attgttttca aaaatacgag cgccattagc
     8281 aacaaccaga accactcgat ccaccaaggg actcagtagt tgtctcatgc ggtgaatttc
     8341 attgcccgtc gcaatgacaa aacgaatgcc cctttgatcc aactgatcta aaatcttttc
     8401 caatcgtggg agatcaagct gacctctagc atccagcaag gtcccatcca tatctgtcgc
     8461 aattacctta atcatcattt actttcctct ggattcaagc taataccact tcaatcccac
     8521 atgttcattc atttctttat aggctgtatc aattcgttcc ttagtcgctt catctaactg
     8581 gtcacgatga ctgccacccc tctataaaat cttccaaaat ataagtttgg taatgataca
     8641 agggatatcc ttctggtgaa aaggttccct ttggtgttcg attgacccaa gtaggatgag
     8701 ctttagctgt tccgatagtt gtttttccat ccttcttctt gatggtgaca tccatgagaa
     8761 caccacgttc agtccactta gcattctctt catctcccat agattcaatc cgttgattgg
     8821 aaatgaagtt ccccatttaa tagacaatga gcttcttatc tccatctttt tccaccgttt
     8881 cagatggttc aacaacgtga ggataccctc caaagataat atccgctccc caatcgatca
     8941 tcttgtgata aagagctttt tgttcttcag ttggttccaa tcgatactca acacccatct
     9001 gaggcatgat aatggtgata tctgcttcct tctctgcccg ttcaacttca gcctttatct
     9061 tatcttcgtt taaatctgaa agataacgat tatagtcttc ctgagaaata tactgctcaa
     9121 ttccattgaa accataggaa taggctaaca atgcaacctt gataccattc acttccttaa
     9181 tgaccagcgg agcctgatca cgtggttcgt gcgtataaac tccgattgga gtgattccag
     9241 ctttctcaat aatatcggcc gttgaaataa ctccctcaat ttgcgaatcc aaaatatgat
     9301 tatgagctaa atccagcaca tgataacctg cctccttaat agcatccata acttcagcag
     9361 gagcattaaa gagaggataa cccgctaaat aatgatcctt attaatggtt tcttcaaaat
     9421 caccaatagc taaatctgct tgcttgaacc aaggagtcac atactcaaaa ttttcatgaa
     9481 agtcataggt accgtcttct tttttagctg aaaagaaaag tccatcgtgg tagagcaaat
     9541 ccccgtgggc cataattctg gcagtttttt cctcttccta ctcctgagac ttttgcttag
     9601 ttccctcttg agaaatagta tctcgttttt gactagtaaa gagattcctt ggaagctttc
     9661 aaacaacaag accaagccca ttgataaacc aactgctagc aagagtatcg ccacaaatcc
     9721 cttattgctc cacttgcgat aactcctaaa aagtttacca agcccttcat aaaacgaaaa
     9781 gctaaaccac cctgatttcg attttgtctt ctttgtatct tcgtcctccc tactttctta
     9841 tgcaagcctt ttctttttat tatatcacag ataagtattt ctttcacaat tgaattgaac
     9901 ttcccatcta ttttctataa atcctaaatg ccataatgct ttcaattctt gtcattttgt
     9961 gatatcatgt agaggaaatg aactaatcca cagtggctta ttccaagtat accacttggg
    10021 ctttggcagt agctaactgc actaaacata atataaggag agaaaatgtc tgcaatagaa
    10081 cgtattacaa aagctgctca cttaattgat atgaacgata ttatccgcga gggaaatcct
    10141 actctacgcg cgattgctga gaaagtcact ttccccctat ctgaccagga aatcatccta
    10201 ggcgaaaaga tgatgcaatt ccttaaacat tcccaagatc ctgtcatggc tgaaaaaatg
    10261 ggactccgcg gtggtgttgg actggctgct ccccagttag atatctcaaa acgcattatc
    10321 gctgttttgg tacctaatat tgttgaagaa ggcgaaactc cacaggaagc ctacgatttg
    10381 gaagccatta tgtacaatcc aaaaatcgtc tctcactctg ttcaagatgc tgctcttggc
    10441 gaaggagaag gttgcctgtc tgttgaccgt aacgtgcctg gctatgttgt tcgccatgcc
    10501 cgcgttactg ttgactactt tgacaaagat ggagaaaaac accgtatcaa actcaaaggc
    10561 tacaactcca ttgttgttca gcatgaaatt gaccacatta acggtatcat gttttacgat
    10621 cgcatcaatg aaaaagaccc atttgcagtt aaagatggtt tactgattct tgaataaaga
    10681 aaatcccgtt gcaagacggg gttttgtgtt ataatagagg catgaaaaca aatgatattg
    10741 tctatggtgt ccacgccgtt accgaagctc tccttgcaaa tacaggaaac aaactctacc
    10801 tccaagaaga tctccgaggt aagaatgttg agaaagtcaa ggaactagct acagaaaaga
    10861 aggtgtccat ttcttggaca tcaaaaaaat ctctctctga gatgactgaa ggtgctgttc
    10921 atcaaggttt tgttctacga gtgtctgaat ttgcctatag cgagctagat tacatccttg
    10981 caaaaacacg ccaagaagaa aatccacttc tattgattct agatggtcta accgatcccc
    11041 ataatctggg ttctatcttg cgaacagccg atgcgaccaa tgtttcaggt gtcatcattc
    11101 ccaagcaccg tactgtcgga gtaactcctg tcgttgccaa aacagccaca ggtgctattg
    11161 aacacgttcc aattgcccga gtgaccaacc tcagtcaaac cttagataaa cttaaggatg
    11221 aaggtttctg gacctttgga acggatatga acggtactcc ttgccacaag tggaatacaa
    11281 aagggaaaat cgccctcatc attggaaatg aaggaaaagg tatctctagc aacatcaaaa
    11341 aacaagtcga tgagatgatt accattccga tgaatggaca tgttcaaagc cttaatgcca
    11401 gtgttgctgc ggccattctc atgtacgaag ttttccgaaa tagactataa aaaagtttcc
    11461 agtcatctga ttggaaattt ttttatgatt aactatgttc tgtaatgaat ttataggctt
    11521 cttgaccagc gatagctcca tctccaaccg ctgttgttac ttggcgaagg tctttcaagc
    11581 gaacatctcc aactgcaaag ataccgtcga ctgcagtttt catgtggtta tctgtcacaa
    11641 tccatcctgc ctgatcttgg atattcaatt ctttaacaaa atcgctaaga gggtccaaac
    11701 caacatagat aaagacacca ccgaaggctt gttctgtcac ttgacctgtt ttcacatttt
    11761 caaatacgac tgattctact cggttttcac ccttgatttc ccttactaca gaatcccaga
    11821 taaagctgat tttttcattc gcaaaggcgc gatcttgtaa aaccttttgg gcacgaagtt
    11881 ggtcacgacg gtgaacaatg gtaacagtct tagcaaaacg agtcaagaag agggcttctt
    11941 caacagctga atctccacca ccaactacca ataaatcttg gtcacggaag aaagcaccat
    12001 cacacacagc acagtaagaa acaccacgac tgttcagttc ttcttctcca ggcactccca
    12061 aaggacggtg tttagaacca gttgctacga taactgtacg tgtttcatat gtttggtcat
    12121 cagtcatcac tttcttaaaa tcaccatggt cttcgacatt ttcaacataa ccataaatgt
    12181 gctcaacacc aagattttca agtggttcaa acatcttttc agccaattca ggtccactaa
    12241 tattagcgta tcctgggtaa ttttcgatat cagatgtatt attcatctga ccacctggca
    12301 gaccaccttc aatcaaagct acttttagat tgcttcgagc agcatacaag gccgcagtca
    12361 tccctgcagg tccagcaccg ataataatag tatcgtacat atagattcct tctttcttgt
    12421 tgtaactatc tttattctaa ctctttcttg tcaatcacgc aaggattatg ccttgaaaac
    12481 aagaattaaa ctcataaccg caaaggataa tactgggaca accaagactc caatcataat
    12541 catatcatag agatgggctt ggcgagccct ggctgtctta tcaactcccg acatggctct
    12601 cagaccaatc caaatcccta aaaaaatcag aacaaggatg gtggtcaaga tcaaactctc
    12661 gaaatataaa gaaaatagtt gcagtagcat gatttctctc atttctatct tttttaaaga
    12721 gtaaactcag ctagtccaac taactgagtt ttcctttatc tattatatca aatataagtc
    12781 cgtttgtaac tagcgaagaa ttcttttgtc cgctcttctt taggggtgtg gataatctca
    12841 tccggagttc cagactcgat gattttcccc ttatctaaga agagaatttt atccgcaact
    12901 tgggctacaa agggcatgtc atgactgacc aaaatcatgg tctgacctga cttagcagca
    12961 tctgcaatag acttttctac ttcaccgacc aattctgggt caagggctga agttggttcg
    13021 tctaagagca aaacatctgg tttcatagca agcgcacgcg ctagggcaac ccgttgcttc
    13081 tgtccacctg ataaatggcg aggataatgg ttttcacggt ccgaaagccc aaccttagcc
    13141 aactcttcct tggcaatctt agtcgcttct tggtcagata atttcttgac aacaaccaag
    13201 ccttctttca cattatcaag tgctgttcgg cgttcaaaca aattaaactg ttggaaaacc
    13261 atagacaact tacggcgtag ggcaaggatt tcttcttgag taattttaga aaaatcaact
    13321 gaaaaaccat caatctgaat agagccactg tcaggtgttt caagataatt gagactgcga
    13381 agaaaggttg attttccagc tcctgaagaa ccaatcaagg ctacaacttc ccctttttga
    13441 atatccaagt ccagatgatc caagacagtc tgtcctgaaa aggatttgct taaattcgaa
    13501 atcttaatca ttaacgaagg tctcctttca catctgtttg cactgtatca ggtgcagaaa
    13561 tagccatttt tctctcgatg aaacgaccga ggctttcaat tccgatattg actacccaat
    13621 aaacaagggc aacggagatg aagcgttcaa aatagcgata atcagctcca cctagaatct
    13681 gagcttgggc aaagacttcc acaacacccg cactaaaagc tagagatgtt cccttggtca
    13741 aaccgatgag ggaattaatc aaggttggag tagctaccac cgctgcatta ggaataatca
    13801 ctcgtcgata aacttgcgct cgggtcatac ccagactgcg tgccgcctca atctcaccag
    13861 gattaactga gagaatggct gcacgaatgg tttcactagc ataagctgcc tcattaaagg
    13921 caaaggcgac aatcgcaaaa gctgcagctg gaatcgcatt gatattgaga ccagttcccc
    13981 attgctgatt gagggctttc aaagccaaag ggattccgta gtaggtcaac atgagttgca
    14041 ccaaaatcgg tgtccctttt aagaaactaa caaagaaggc ctgcaaggga tataaaatct
    14101 tgacacgatt gatcttcaca atggcaaaaa gaagcgccaa aaccaagcca aaaagggcac
    14161 caccaattgt caacataatt gttgttggaa gttgttggac aattctaggg attccatcaa
    14221 agaccgaacg taggctaaac agcttgccat ccggaatcaa ttgcatcaag ttttggtacc
    14281 aatctgatgc taaaatcgtt gtaacattca taaaaacatc ctcttctgat aatgattcat
    14341 tctaccatgc ttctgccgtc aatgaaatta tttgctacgg tcagatacag actttgtcta
    14401 cctactagtt tatcatactt tgaaacaggg aagttatata ttttatctat caaagagata
    14461 gataaaaact atttcagtcc cagttcttca taagattttc gataaccgat ttgcttaaca
    14521 gttccatttt ctactaaaat gggccgtttt aacaacatac cgtcacttgc tagcaactca
    14581 gccgcttctt ggtttgacaa acttcctacc ttatctttta gccctaattc acggtatttg
    14641 ataccactgg tgttgaaaaa ttgcttcaat tcaaatcctg aggtttctag ccaattcaaa
    14701 atgacttctt ggctaggtgt ttcttccacg atatggacgg ctttatagtc cacacctaat
    14761 tgatttaatt cttgttttgc ttttttacaa gttgaacatt tggggtattc gataaattct
    14821 aacatgtgct tctccttcta tttgtttata tctttaaaat ctacgccttc atgctccaag
    14881 agccaagctt tcttttccac tcctgcagca tagcctgtca gacgcttgcc tgctcccaac
    14941 acacgatgac aaggtactag gatagaccaa ggattgcgtc ccactgctcc accaattgct
    15001 tgagcagaag ccacttgcag gtcttgagca atttgtccat aggtcactgt ctgaccataa
    15061 ggaatgccct gtaaatagtc ccaaactctc ttttcaaaat tcgttccgat tggcgccaag
    15121 agcaagttgg ataaatcctg aggcttgcct ttaaagtaat catctaagca agcaataact
    15181 gggtctaaaa taggatgact aacaacttct tctatcgttt catctcctag tcccctctca
    15241 aaatgcttct gctcctgaac ccaaattcca tacaaataat ggtcatcagc tacaagtgat
    15301 agaataccaa ttggtgagga gtagaggatt tttacatact tcttttgcat tatttcttta
    15361 atttttgata ggccaagcgt ttgccatcta ctggcacctt accaacttgt ttaaaaccaa
    15421 gtttttcaaa aatatgttgc ataaccttgt tttcagcatg cgtatctgag cgaaaatcaa
    15481 gataatcaaa accttcaatc aagccctcta agaaggtttg agcaactcct tttccctgca
    15541 catctgctgc cacagcaata cggtgaaaga ctagatactc tgactctcca gcttgccagt
    15601 ttccctcata aatagcttca taggcctcct ctggactctt ggtcacagca gcataggcta
    15661 gcagttctcc ctcttccaag gctacgtagg cttgccctga gatgatatca tcgataataa
    15721 catctgcatt tggatagcca ttttgccact ggttactacc agcatctgct aaacattttt
    15781 tggcatcctc tatcacctgc atgatggcat ctacttcatt tggaaaagct aaacgaattt
    15841 ccatcttttt tcctcatttc tgactagttt ctcccatcat agcataattt aagtctttct
    15901 acaagcagtt aaaacttgac tttgtatttt tgttatttta taatctagtt atcaaaacta
    15961 tataaaaagg agttgaaaat gaaaactacc ttttcctacc caaaatgggc agaaattcca
    16021 aacattaacc tctatctgga ccaggttttg ctctatgtca atcaggtctg cgcccctatc
    16081 tctcctaata aagacaaagg cctaacagca tctatggtca acaattatgt gaaaaatggt
    16141 tacctgacaa agcctgacaa aaaaaaatac caacgccaac agattgcccg tttgattgct
    16201 atcacaaccc tcaagtctgt attttctatt caagaaatag cccagacact taatactcta
    16261 caaactcaag caagttcaga ccaactctac gatgcttttg tggactacat gaaccaagga
    16321 attgacccag ctaaccctat tatccaaacc agctgccaaa ccgttaaact ctatcatcaa
    16381 actctagact taatcgatca tactcaagag gaggtaatcc aatgaacact agtcttaaac
    16441 tcagcaaaca actcagtttt ggagaggaga ttgctaatag cgtgacccat gctgtgggtg
    16501 cagtcatcat gcttatcttg ctgcctattt catccatcta tagttatgaa gcacacggat
    16561 ttttatcctc tatcggcgtt tccattttcg tcatcagtct ctttctcatg ttcctatcat
    16621 ccaccattta tcactctatg gcctatggtt cgacccacaa atatgttttg cgaatcattg
    16681 accattctat gatttacgtt gccattgccg gctcatacac gcccgttgtc ttgaccttga
    16741 tgaataactg gtttggctat ctgattattg tcatccaatg gggaacgacc atctttggta
    16801 ttctctataa aatctttgct aaaaaggtca atgagaaatt tagccttgct ctttacctga
    16861 ttatgggctg gttggttctg gctatcattc ctgccattat cagtcaaacg acacccgttt
    16921 tctggagtct catggtaact ggcggactct gttatacagt tggagctgga ttttatgcca
    16981 agaaaaaacc ttatttccac atgatttggc atctctttat cctagctgcg tccgcacttc
    17041 aatacatcgc tattgtttat tacatgtaaa aaagttgaga aattcaatct caactttttt
    17101 ctttacacat attgataaag tactggtgca agcgcacatc atcagtcaat tctggatgaa
    17161 aagaacttac caacatattt ttttcttggg ctgcaacaat ttgattgttc actgttgcta
    17221 gaatttctac accctcacca acactactga taatcggacc acggataaag gtcattggaa
    17281 tcttgccaac tcccttacat tctgcttccg tgtagaaact tcctaattgg cgcccataag
    17341 cattacgctc gaccaccata tccatagttc ctagatgact ctctttctga gaagtgattt
    17401 ccttagccag caaaattaag cccgcacagg tcccaaacac tggtaagcca gatagaatgc
    17461 cttctcggat gggaagtagc atgttctggt cacgtaagag cttgcccatg gttgtagact
    17521 caccaccagg caaaatcaaa cccgacaagt cactctgatc ttgctgaaaa tcatctagat
    17581 ttctgagttc tacactctcg acacctaatt gatctagcac ttttgcatgt tctgcaaagg
    17641 ccccttgcaa ggccaatatt ccgattttca tctattttcc tcgttcagcc atgagaattt
    17701 ggatttcatt ttcattaata ccaaccatgg cttctcctaa atcttcagag atttgagcta
    17761 ggatttgagg attacggaag ttagtcacag ccttaacaat ggcactcgct cgtttaacag
    17821 gatctcctga cttgaaaata cctgaaccga caaagacccc ctctgcccct aattgcatca
    17881 ttaacgcagc atctgctggc gttgcaacac ctccagcagc gaaatttaca actggcaatt
    17941 ttccatgttc atgaacatat tggaccaatt ctacagggac ttgcaaatcc ttggcagcaa
    18001 cataaagctc gtcctcacgt aagttttgaa tgcggcgaat ttcctgattc atcatacgca
    18061 tatgacgaac agcttggacg atatcccctg tccctggttc tcctttggta cgaatcatgg
    18121 aagcaccttc agcgatacga cgcaaggctt cacccaaatc cttagcacca cagacaaaag
    18181 gaacttggaa ttctttcttg tccacatgga aacggtcatc agctggagat agaacttcac
    18241 tctcgtcgat ataatcaatt tcaatagcct ctaaaatctg agcttcaaca aaatgcccga
    18301 ttctgacctt agccattact ggaatactaa ccgcttcttg gatttcctta atcatctttg
    18361 ggtcgctcat gcgggaaact cctccagctg cacgaatatc agccggaatt cgttccaagg
    18421 ccatcacagc tgccgcacca gcagcttctg cgatacgagc ctgttcagga ttctgcacat
    18481 ccataataac accacccttg agcatctgtg ccaagttttt atttagttca taacgatttt
    18541 cagtcatttg ttttatcctc atcatttgta ttggtagcta ccttttcatt ttaagtcaga
    18601 acagaatgaa gcacaagata aaaaaactat aattgtatgg ggacagatta gctaaaaact
    18661 atctgacctt aacttaaggc cagatagctc attcattttt atttttcagc cgtaagggca
    18721 gccattgtga tgtagttgta tggtttgttg aagtgtggca agaagaagag gtctgtcaat
    18781 gccaatttat caattgtcac atgctcttgg atagcaagtg agaacatgtg gattcccatg
    18841 ctaattgcaa tatcatgtga aaccatttgg gcaccaagaa tttcacggct atctttgtca
    18901 aagacaatct taattgctac ttcatggttg tcatgtttca tgaattctgg tttttgaaga
    18961 tcgttaaagc ctgtttcagt tgcgttgtaa ccagcagctt tcgctttttc aagagtcaaa
    19021 ccagttgaaa ccatgtgaag accgtagatt gagataccat ttgaaccttg aacaccgatt
    19081 ccttccaatt catgtccaca agcgttgtag gcaccaacga taccagtgcg aacagcattt
    19141 gaagcaagag cgatatagct tgtatcttta cgagcattgt cataaacagt cgcacagtca
    19201 ccaacagcgt aaacgcctgg gatagatgtt tcttgtttct tgtctacaag gaaggcaccg
    19261 ttgcggaaga gttcgatctt accatctgca agggctgtgt ttggacggaa accaactgca
    19321 aggataacca tatccacgtc aaagctttct ttgtcagtaa tcaagcgttc aactttaccg
    19381 tcaccttcga ttgctttaac agtttgacct agagccaagc ggatgttgtg atcttccaag
    19441 ttcttcgcca tcatttgtgt gaagtctttg tcatagtaac cgttcaagac agtatcaacg
    19501 atatcaacaa ggacaacttc ttttccaaga cgttcaaagg cttcagcaag ttcaacaccg
    19561 atgtaaccac caccaacaac ggcgatacgg tcgaggtgtt ggctcttgtc agaaagttta
    19621 ttgataactt cttcagcatt ttggtacaat ttcacgaatt gtacgttttc aagagttgct
    19681 ttaaattcgc ggtttccttt aacaatttca acaccttcga ttggtggcaa gattggtgta
    19741 gaacctgtag cgaaaatcaa tttttcgtat gattctttgt gctcttttcc ttcaacttcc
    19801 gctgtaacta ctttgttatc atagtcgatt gaaagaacag gtgagttcat gtaaacttta
    19861 gcacctttag cttccaattt ttctttatca gaatagaaca agccttcagc accgtcaatt
    19921 tgttcaccaa tccaaagagc cattccacat cctaggaaag agatgttaga gttttggtca
    19981 aatacaacaa tttcgttctc atttccaaaa ttatccaaca tggtattgat acatgctgta
    20041 ccagcgtggt tagcaccgac tacaacgatt ttactcataa aaatttcctg ccttcattct
    20101 aaatttacct tactagtata ccatttaccg ttagcgttta caaggggggt actattattt
    20161 cagcattttt tatcaaaaat aattccccat ttatcctgtt ttcaagcctc atgaatttta
    20221 tgagcatatt tcttgacttt ttccaaattt tgtttgtgaa aattctaact ttatggtatt
    20281 ataataacat gaaaatgaaa tgtaagggct tcaatttaga tgattatttg atattacaac
    20341 ttattttcta taagagaaag gagttggtag cttgactctt cgttcacatt ctgaacggct
    20401 aatggggact actatcacta tttcattagt ggatgagcaa gccgatatct ttctccaaaa
    20461 atcctttgac ttgctcaaag aacttgaata ccgcttcaac gccaatagtc aagaatctga
    20521 gttgatggaa atcaattatc aagcaggaat agcccccgtc acggttcatc cagacctgtt
    20581 tgagctgatt tcacttgggt tagagcatag cctagcgctc tctagccacc tcaatatcag
    20641 cattggtccc ttaattcaaa cctggcgtat cggtttttca gatgccaagg tcgcccagcc
    20701 tcaagaaatt gaatcggtgc tgcctctaat caatcctcat ggtatcgagt tagattcttc
    20761 tacttctact gtgtttttaa aacagaaagg aatgaagatc gatctaggtt gtttagccaa
    20821 aggatacagt gcggataagg ttgcccaatt tcttaggaaa gagggggtga cttctgcctt
    20881 gatcaatctg ggagggaata tcctgaccat tggaaaaaat caggcaagag gggataaccc
    20941 atggcaaatc gggattcaag acccagccaa tcctagggga aatcatttaa tgaccatccc
    21001 tgttgtcaat aaatctgtcg tgacttcagg catttatgaa cgtcacctga ccgtcgatgg
    21061 acaagattac catcacattt ttgacagtca aacaggatat cctgttgaaa cggaactagc
    21121 gagtctaaca atcatctctg ataaatcagt cgatggcgaa atctggacga ctcgactctt
    21181 tggagaaaga cctgcttcta tcctctggca agtcgaaaat ttggagggca tcgaagtcat
    21241 cctcatcgat aaagaaggcc acctaagctg ttcttcagga attcctactc tatagagaca
    21301 actgtttcaa tggaatttta aaattgtatt atgtaaaaag agaaaggaaa tctcatgtta
    21361 aaacttattg ctattgttgg aacaaattca aaacgttcta caaaccgtca attgcttcaa
    21421 tacatgcaaa aacactttgc tgacaaagct gaaattgagc ttgttgaaat caaggccatt
    21481 cctgtcttca acaaaccagc tgacaagcaa gtacctgctg aaatattgga aattgctgct
    21541 aaaatcgaag agacagatgg cgttattatc ggtactcctg agtatgatca ctctattcca
    21601 gctgttttga tgagcgctct tgcttggttg tcttatggta tttacccact tttgaacaaa
    21661 ccaatcatga ttacaggtgc ttcttacggt acgcttggtt catctcgtgc ccaattgcaa
    21721 cttcgtcaaa tcttgaatgc tcctgaaatc aaggcaaatg ttcttccaga tgaattcttg
    21781 ctctcacact ctcttcaagc atttaaccca agtggcgact tggttgacct tgatgttatc
    21841 aagaaattgg atgccatctt tgatgacttc cgtatctttg taaaaatcac agaaaaatta
    21901 cgtaatgcac aagaattact tcgcaaagat gctgaagact ttgactggga aaatttgtaa
    21961 gataggagac caaaaagaat gaaatttgtt ggacttgttg gatcaaacta cgatcaatca
    22021 tataaccgta agctcttgga atttatccgt cgctacttca aactcaaatt tgaattagaa
    22081 gttcttgaaa ttgacgaagt tccaatgttt aaccaagatg aaaaatggga tgaaagtttc
    22141 caattacgtt atttatataa caaaattact cgtgcagatg gtgttatcat tgctactcct
    22201 gagcataacc acactatctc agcttcactc aaatctgtac ttgaatggct ttcatacgaa
    22261 gttcatccat ttgaaaacaa gcctgttatg attgtgggtg catcatacta tgaccaagga
    22321 acatcacgtg ctcaagttca ccttcgtaaa atccttgatg ctccaggtgt taatgcctac
    22381 acgcttccag gtaacgaatt ccttcttggt aaagctaagg aagcttttga taacaacgga
    22441 aatatcacca acgaaggcac tgttaaattc cttgaaactt gcttagataa ctttgttaaa
    22501 tacgtaggag tcgtttcgaa attgaaaaaa ccaaaaccaa tcgaatcaga agacttggat
    22561 tgtggaaaac caatcgctac aaccatcaca gaagttgacc ctgacgatcc agaatgggta
    22621 gaaaaagttg cagcaatcac tggtgctgtt tctggtgata cctatgtcaa attggaccac
    22681 ggtatcctaa cagttaacca aattgatatg ttcttgaaag ctatgccatt tgaattgaca
    22741 tacgctgacg ataacaacca attcctctac tacaacaacg ctcaccaaga tccagacact
    22801 atgttcgcta aacgtgtacc acctcaatca ggtagccgta tgtcgactgt tcatggttct
    22861 cttccaccag cacgtatgaa gaacgtagag tgggttatcg gaacacttcg caacggaaac
    22921 caagaatacg tccgtacgat cgttccaggt tctcctgcag gtgttatcaa cactcacaac
    22981 taccaagcaa tgtactatcc tgatggatca tacgctggta tcaatgaaat cgtctttaac
    23041 ttccaaccat ggcttgactg gtacctaaaa gagactggtc aacgtttggt gggtggtagc
    23101 ggaccatttg ctcctgctgc cggaggtcat ggagacgccg atgctacttc tggcgcttct
    23161 gattcagggg atgctggagg ccacggtggt gacgcagacg ctacagccgg tgcaagttac
    23221 taatgatagt ttttaggaac cattatggtt ccttttttag cgaaaaaaga ctagcaaaca
    23281 caaactgcta gtctctttgt tatcgtttca tctatctttg ttaaaagaaa gaatacatat
    23341 tatgaatttg gatcatcaag actacggcca tgtaatcctt tttcacgttg tacttggcgt
    23401 agtttttctg gtgtaacatc gtttccttct tcgtccacaa ttttgattcc ttcaatgtgg
    23461 tgacgaacag cgcggcgata accttcgatg tactcctcac gtagtttggc ttgttccact
    23521 ttttcttctg gtgttaagcc ttctgttttt ttctttttag caagctcatt gatacgagca
    23581 atttttttcg gatccatttc ttctcctctg taataagata aagtccgttt atcaaatttt
    23641 atttagtgtt aatttggtta aaacaagcaa acttagctgc tttcttggtt agttgtgaca
    23701 agattgccaa acgattttga cggacagcct gatcttcagc cattaccata gtattttcaa
    23761 agaaagcatc aatgactggg ctaagcgcaa agagttgttt caattgctga cttgcaggtc
    23821 ctgataaaac gagtgtttct actgcttctg ccaaagcttt ttcttggtca ttctcaaata
    23881 gtgctgaatc aaccgtagca accccttctg ccttctcagc caggttaaag gcacgagaaa
    23941 gtgattcaac agatggttta aaatcttctt ccttgcttac ttctacgaga gcacttgctg
    24001 cttccaacat atctgccaca acaaagtttg aacctgcaag aactgcttct ttgatatctt
    24061 ttggagtaga gcccatcatc ttatcaacac gagccttgat aaagtccata acctctgctt
    24121 tattttcata agtcaaactg tcaaatttca atgcataaag gctatcaatc agctcatcca
    24181 tagcaatgtg ccaaccaaag gcatccaaga tacgaaccac accttgagtt gcacgacgaa
    24241 gggcataagg gtcattagaa cctgatggaa tcaatcctac tgagaagaaa ctcaaaatcg
    24301 tatccaattt gtctgcaatg gctagaactg cgccgacctt gctctctgga agttctcctt
    24361 cagctgatgt aggcatgtag tgttcacgaa tagcagctgc caccgctgga gtttcaccag
    24421 caagaagggt gtatttttca cccataattc cttggagttc gtcaaattca ccaaccatac
    24481 ctgtcaacaa gtcaaacttg taaatggctg ctgcacgagc aaggtcaact gtttcatcca
    24541 ctgacaaacc agctttttct gccaaaagta cagtgatttg acccgtacga atcatgtgtt
    24601 cacgaaggga accaatcttc tcatggaagg tgacattgtt taatttttca acaagatctg
    24661 aaatcaccaa tttttggtct tcacgccaga agaattctcc gtcttccaag cgggctacca
    24721 agactttttc atttcctttg atgacatttt tcaaacgctc tgcgtttccg ttacgaacag
    24781 aaatgaagtt tggcaagagt tttccatctt gatcacgaac aacaaagtaa cgctggtgtt
    24841 ccttcataga agtcaccaag acttcttctg gaacttcaag gtatttagca tcaaaacttc
    24901 ccatgaaggc agttgggtat tcaaccaaat tcaagacttc attcagcaaa tccgcatcaa
    24961 tttcgatacg tacaccatgt tttgcctcaa tttccttgat ttggtcaaca atcatttgct
    25021 cacgttcaca tggatctgcg attacaaact gcttacgaag gtcttcttca tagctcaatg
    25081 ctgactgaat tttggtttct ttccccaaga aacgatggcc acggctcaca cgacttccct
    25141 tgatatcaag gaaatccaag tcaaactctt gctcatccaa gagaacagtt aaagtgtgga
    25201 cagggcggat gtattcaaag ctatttccag cccagtgcat gctgacaggg aaagtcaatg
    25261 acttcaagac atctacaaca ccaggaacaa tggcttcaac tgcttgacca acttcttcct
    25321 tagtgacata gacatattct tcacccttga tttcacggaa ttcgatatct tcaacagtca
    25381 agccttttcc acggacaaat ccttgagctg ctttggtgaa gtttccatca ctatccaagg
    25441 caattttctt tgctggtccc ttgaaatctt ctgtcaaatc agactgtttg tctgataaac
    25501 cagtcacacg aacagccaaa cgacgtggtg ttgagaaggt ttgaatggct tcaaaagaca
    25561 ggcggttttc cttgaggaag gctgccattt tttcgcctag ttgtttttca cttggtgtga
    25621 caacataggc tggtaattct tcaagaccga gttctactaa taagtttttt gtcatgtttt
    25681 ttcctttaca ttttcttcaa tcttttttga tatgcacctt aggtactggg gacgtcgcta
    25741 actaactctg tgagtctgta tggaaatcca atgctaaatt tatcaagatt tccaacaatc
    25801 tcatcaaagt ggatttagct gactgatttt tgaacctaag gtttcaaaaa tccccacata
    25861 acagtacggc ggtgcatatc cctctagcaa gtcttcgact tgcctctaac gattttagag
    25921 tacagtatta ctcactattc tgcgtcttct gctaaaagtt tagctcttgt ttcttcatcc
    25981 aaaagtgggt agcctaggcg tttgcgttct gcgacaaagg ttttggctac gacacgggcc
    26041 aagttacgga tacgagcgat atagcctgca cgctctgtta cagatacggc accacgcgcg
    26101 tcaagcagat taaaggtatg tgaacatttg agaacatagt cataggcagg gtgtaccaag
    26161 ccttcttcta atgcacgacc agcttctttt tcaaacttat caaagttttc aagcaacatt
    26221 tcttggtccg aaatttcaaa tgaatatttt gagtgctcat actcaggctg gataaagatt
    26281 tctccgtatt ttacaccatc agcccactcg atatcataga cagagtctac ttcttgaatg
    26341 taagaagcca agcgctccaa accataggta acttccgcag tcacagggct agttgccaat
    26401 ccaccgactt gttggaaata agtgaactga gtgatttcca ttccgtcaag ccaaacttcc
    26461 caaccaagac cagctgaacc agttgatggg ttttcccagt tgtcctcaac aaaacgaata
    26521 tcgtgctcca aaggattgat tcccaatttt tccaaagact caaggtaaag ttcttggata
    26581 tttgatggag aaggcttcat gaccacctgg aattggtggt gttggtagag acggttaggg
    26641 ttttccccat aacgaccgtc agcaggacga cgtgatggct ctacataagc tgcattccat
    26701 ggctcaggtc cgatagcacg aaggaaagtg taaggactca ttgttcccgc acctttttca
    26761 ttatcataag cctgcataag catacaacct tggtcattcc aaaattgttg caaagtcaaa
    26821 ataatttctt gaaatgttaa tttcttagac attgaatact ccttaataaa aaataattac
    26881 ttgcgacacg agtctgcctc gtcgatcata cgaggcaaga cgagttagta ctgcgtctag
    26941 ctcaggcact ctagtgctga gcgtggggca gtccgactgt aaggaggttt ctgccactga
    27001 tgcagtgaaa tgttaatttc tcagacattg aatactcctt tagtttttat atttcttttt
    27061 caattaattt ctgctgaaca aaccaatcta acaagggaaa agttttttct gtatttgccc
    27121 ataaatgata agaatcaaag accgcttgta cactacctaa attttctacc aacttatcta
    27181 ctgtcaaaaa gctgcgccag tattcataaa aaatacttgc atagttctta tcataagtcg
    27241 aagaaccaaa atcattcaat gaatgccaac catacttctt ctgaaaaagt tctacgagag
    27301 attgattaca aattttttcc gcttgaaatt cctcttctgt caagaaatac ttgcgactaa
    27361 tatattcaac catcccctct tcgaaccaga tataagagtc ataaccatca aaatcatcta
    27421 aaaaatgctc cgaccaatga gctaactcat gtcctacaat ctgtaagagg aaattttcag
    27481 ataaagaatg atagtggctt tctattgctt gagtttgctc agaacactcg tagtccatca
    27541 actgatacaa atacaactct ttccaaacag ctaaatcagg cgtcataacc attcgtctat
    27601 tatttgtata ggctggaaca gcactttccc taataatctg tgtagcagca ttaagatctg
    27661 accaaataac ggcttgcggt aaatcacaga ctgcaagttc attctttaaa aaagattgat
    27721 aatctttcaa cttttcagta tttcttacta caaaatcacg aaatgtagct agttgactat
    27781 cgtcttttac aagataaagg ttgtccacgg ctctcctttc tttcacacaa tagactgaat
    27841 aagcaaaaga accacatctg acaagcctag gttgatttaa cctaggggcg tcagaaacgc
    27901 ggttccaccc taatttatta cttcattgtt tttgaaaata ctacagaaag cgccagccca
    27961 ttattttgcc ctacttggct cccactgtcc caagctcgct tgaagaacgc cataagactt
    28021 tctttcctgc tgactattat atcaaaaatt agaataatgt acaattcttt ttatgatttt
    28081 ctagaaatcc acatcatcaa ctcgtggagc acccaattga acagcaatcg tttttaaggt
    28141 ttctctctcc ttatgactca gttcaattcc aaagcaatca agattagcct gaatacgaga
    28201 gattgtgata gattttggaa gtggtaaaaa tccttctgcc aagctccagg ccaaggctat
    28261 ctgagcaacc gattttccgt gatttgctgc tatttcttgg acttgcttgc tatcaaacag
    28321 ttctccttgt ccaaaaggcc cccaagcttc caataaaatt cccttttcac gacagtaagc
    28381 tacgacttga tcttgataca cacctggcgc caagcgaact tgattgaccg caggaacgat
    28441 agttgcagtt tcaagcaagg catccaaatg atggggaaga aaattgctaa cgccgatagc
    28501 acggattttc ccttcttgat agaggtcttc catcgctctc caaacttccg cattgcgagt
    28561 tttccatgcg tcattttctc tgagcggttt tgggttcggc caatgaatca aatacaaatc
    28621 caaataatcc aagcccagtt tttctataga tttttccaaa gcttgacgag tttgctcata
    28681 ggtttgctga ctattccaaa gcttggtagt tacgaacatt tcttcacgtg gaactccgct
    28741 atctttgatt gcttgaccaa cactttcttc attctgataa atcgccgccg tatcaatatg
    28801 acgataacca gccttcaagg cttctaacac tgcacgatag gcttcttctc catccttagc
    28861 cttaaaagtt ccaaatccca atactggaat ttctactcca ttatttaatt gataggtatt
    28921 catatgcttc tccttctatt ttattcatca attatagcat aaaacatttt ttaagtagta
    28981 ctatcttctg taaaaaataa gtctgtcaaa tatctaacag acctattttt tcttgcttat
    29041 tcatcacgac tatagtacag ctcatgagct tttaggcgag tattgagcat ctctggtatg
    29101 gtcacaaagg tataaccttg atttttcaaa tactcaatga cccttggcaa ggcattgact
    29161 gtcggactgt gaatatcatg catcaaaacg atagagccgt tagctacttg atgctgaatt
    29221 tctgtcaaaa tagatgcttc atttttactc ttccagtcca gactatccac atcccacatg
    29281 ataaagctca aatccaagct attgcgaata tcatctgtaa tagcaccata aggtggacgc
    29341 atgagtttag aactagaacc cagcacttta gttagcacat cctcagtatc agtaatctgc
    29401 tttttagctt catcaagaga gagttgcgag agaatcggat ggctccaact atggtttcca
    29461 acaacatgac cttcagattt tatcctcttc accaagtcct cattcccaga aacatttttc
    29521 ccaagcacaa agaaagtcgc tttaatatca tatttagcta gggtctctaa tacctgcggg
    29581 gtcgttgctg gatttggacc atcatcaaag gttagagcga caactttttg atgtttctta
    29641 tcaaagtaag attggtacaa ggccgcatct ttttcgagta agtacgaaga ttggataaca
    29701 tcaaagaaag cagatactgg caaggctatc tcttctaaat tttcaaccac aggacttgga
    29761 taaaggataa tctgactatc cttgtaatca aaattccatg cagacaagtc ttggtcagag
    29821 aagtttttta caatctgctc actctggtct tgctctattt ttttatcctc tatgaaggag
    29881 gtcaactctt ttatcagctg ttccttagcc ttactagcat ctgaaaacag ttggtcaagt
    29941 gtaaaaggtt gcccatcttc tgttaagtga acctttccta gactggtctt ttcagtctct
    30001 tcaatcttaa aagcaactaa atcatagatt tgtttggtca cattacgatt aacgactccc
    30061 tttaaacctg actcttcttg ctctgtatag tagaaaacaa gattgtcctt actttctagc
    30121 ttgtccttaa catcttgatt tatcagctcc ctaacagagg aaatcacttt ctccccttgg
    30181 agaggataat aggcaatcac ttcggcttgc ccctgacgaa aatgctcctt ctgatttccc
    30241 tcactcaatt gatcatcttt ctcttttttg agcgattcaa tcttttgctc aaaacttttt
    30301 tgctggtaga tcttaaaagc aataaatccg cctaataggc aaatagaaat tgctaaaata
    30361 ccaatcaaag ccaataatac atgtctcgtt ttcccgtgtc tgccacgtcc tagtctactt
    30421 ttattcatat ttatatcata acaaatttga gcaataattt caatgataca atttggcaat
    30481 ccacaattcc tctagcaagc caaagcatct tacatcaact ccaacatccg tatctgtaga
    30541 gattatgtag ttttctatct atggaatttc tagtagattg aagctagaat agtagaccta
    30601 tacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttctca
    30661 tttcatttca ctataaaact atgaaaagct aggtcatctg agaagtaatt actatcgaca
    30721 attgcgatag cgtatactag tgcgatttgt ttgtagctct ggtgggtatc accttcacgt
    30781 tggcgaattt tttctaggtt ttgattaacc tgactgcaca gataagccca taggcgattg
    30841 atgaaaaaat tctgatgatg aacctgaatt tcgatgataa cttggattcc attatctaac
    30901 tccgccaaga cgtctatact agtatagaaa tcttgcgctg agtagggcat ggaaggcaag
    30961 acgtgaatgt tacttccctc caaaatcgtc acattttttg ctggcaagtc cagcatatcg
    31021 cggataaatt gacaaatcat tagttgggct gatacctgga tgtctgagaa tcctcctttt
    31081 cctccttcta ttatagcaca ttttttaatc taggtttgct agattctatg cttctatcta
    31141 tttattcgga aaagaaagct aatagcttat ttgaaatttt ctcctctctg ttggatagtc
    31201 ccgtctatct atgttataat gaaagaagga tttaaaatcg gaaaaggagt atttatgcta
    31261 aaattaggtg tcatcggaac tggcgctatc agccatcatt tcatagaagc agcccatacc
    31321 agtggagaat accaactggt cgcaatctat tctagaaaac tagaaactgc agcaaccttt
    31381 gcttctcgct atcagaatat ccaactattc gatcaattag aagtcttctt caaatcttct
    31441 tttgatttag tctatatcgc cagtccaaac tccttacatt ttgctcaggc aaaagctgcc
    31501 ttgtctgctg gtaaacatgt tattcttgaa aagccagctg tcactcaacc acaagaatgg
    31561 tttgatttga ttcaaacagc tgaaaaaaat aactgtttta tctttgaagc agctcgtaat
    31621 tatcacgaga aagcctttac tactatcaaa aactttttag cagataagca agtgttagga
    31681 gcagatttca actatgccaa atactcttcc aagatgcctg acttattggc tggacaaaca
    31741 ccaaatgtct tttcagaccg ttttgctggt ggagccctca tggatttggg gatttatccc
    31801 ctctatgctg ctgttcgtct ttttgaaaaa gctaatgacg cgacttacca tgctcaacag
    31861 cttgacaata gcattgacct aaatggagat ggtatcctct tctacccaga ctatcaagtt
    31921 cacatcaagg ctggaaaaaa catcacttcc aatcttcctt gcgagattta tacaacagat
    31981 ggaaccttga ctctcaacac gattgagcat attcgctcag ctatttttac cgaccaccaa
    32041 ggaaatcaag tccagcttcc tatccaacag gctcctcata cgatgactga ggaagtcgct
    32101 gcatttgcac acatgatcca gcaaccagat ctgaatctct accaaacttg gctgtatgat
    32161 gcaggctctg ttcatgagct actatatacc atgcgccaga ctgctggcgt tagatttgag
    32221 gcagaaaaat gaaaaccaaa ctaccgactg aatggcaaga actgagtgac caactcggtt
    32281 tccaagaatt cacccccatt caaactcaac tatttgagct ccttcttgct ggagaaaacc
    32341 tcctaggagt gagccaaacc ggaactggta agaccctagc gtatctccta ccaagtcttc
    32401 tcagactaca aaagaaaaaa gcccaacaac tcttgattct agcaccaaac acggaacttg
    32461 ctggacagat ttttgatgta tgtaaaacgt gggcagaagc tatcggattg actgctcaac
    32521 tcttcctttc aggttcaagt cagaaacgac aaattgaacg tcttaaaaag gggccagaaa
    32581 ttctgattgg aactcctggc cgtatctttg aactcattaa acttaaaaaa atcaagatga
    32641 tgaatgtgga aaccatcatc ctggatgaat ttgaccaatt actagatgat tctcagattc
    32701 actttgtaga gaaaatcact cactacgcac ctcgtgacca ccaactggtc tacatgagtg
    32761 ccacgaccaa gtttgaccaa gaaaagattg tgccgaatac acgcactatt gatctctctg
    32821 atcaaaaatt ggacaatatc cagcatttct acatgcaggt agaccaacgt catcgagtgg
    32881 atatgctacg aaaactggct catgtagagg atttccgtgg tctagtcttc ttcaatagcc
    32941 tgtcagacct tgggaatgcc gaggaaaaac tacagtatcg tgatatattg gctgtttccc
    33001 tcgctagtga tgttaatgtt aaatttagaa aaatcatctt agaaaagttt aaagataacc
    33061 aactaaccct gcttcttgca actgaccttt tggctcgtgg aattgatatc gatagcctag
    33121 aatgtgtcgt aaactttgat attcctagag atagcgaaac ctacacacac cgtgctggcc
    33181 gtactggtcg tatgggcaag gaaggttatg ttatcactct cgtcactcat ccagaagaaa
    33241 tcaaaaaact taaaaagttt gcaagtatcc gagaaattgt cctaaaaaac caagaactct
    33301 atatcaaata aagccccatt gctctataca catccagtgt atggagcttt tttataagca
    33361 attcaatttt atactcatct gctttcaaaa agcattctag tccatctccg attaacgatg
    33421 gactttatca cctccttctc cagtccttgt atgacatctt gaagttgatt catgacatct
    33481 tccaaagttc gaaaggcctt attcttaaat ccacgtttac gaatctcttt ccacacttgt
    33541 tcaatgggtt catctctggt gtgtatggag gaataaaggt aaaaccaata ttagtcggaa
    33601 tctttaaggt acttgattta tgccatatag cattgtccat aacgagtaaa agataatcat
    33661 ctggataagc ttgtgaaagc tcttctaaaa aggcgttcat ccactcagta ttacatccac
    33721 cagctattaa gaaaaatgat tcgcctgtat gggcatcaac agctccataa caatagtgaa
    33781 attctcgtat atagtgacta tggacatgtg gacctactcc tattggagcc caacaagatc
    33841 ccagtttact gattctaccg aaaccagcct catcttggta catcaagcga accttacgaa
    33901 aacgtctact gcttttaaag cgctttcttt tcttcttgaa ttgagatttt atttttagac
    33961 gcgacaatgg tttgagcgtc tgctttccta ggatgttctg gacgtggcat aatatttcgc
    34021 caaccatggt gcttcaacag ttgatagaag gcatcacgtg tgtaggaacg acctaactcc
    34081 tttttataag cctgaaataa ggcatcaatt gtaacaaatt ct
//
LOCUS       DAVHSH010000016        33738 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000016 DAVHSH010000000
VERSION     DAVHSH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.016"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(1..305)
                     /locus_tag="VVR08_000924"
                     /pseudo
     CDS             complement(1..305)
                     /locus_tag="VVR08_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(486..695)
                     /locus_tag="VVR08_000925"
                     /pseudo
     CDS             complement(486..695)
                     /locus_tag="VVR08_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844245.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(668..853)
                     /gene="briC"
                     /locus_tag="VVR08_000926"
     CDS             complement(668..853)
                     /gene="briC"
                     /locus_tag="VVR08_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU6074864.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1012..1779)
                     /locus_tag="VVR08_000927"
     CDS             complement(1012..1779)
                     /locus_tag="VVR08_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU6074865.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(1776..2642)
                     /locus_tag="VVR08_000928"
     CDS             complement(1776..2642)
                     /locus_tag="VVR08_000928"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU6074866.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2679..4046)
                     /gene="accC"
                     /locus_tag="VVR08_000929"
     CDS             complement(2679..4046)
                     /gene="accC"
                     /locus_tag="VVR08_000929"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU6074867.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4058..4480)
                     /gene="fabZ"
                     /locus_tag="VVR08_000930"
     CDS             complement(4058..4480)
                     /gene="fabZ"
                     /locus_tag="VVR08_000930"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU6074868.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4477..4962)
                     /locus_tag="VVR08_000931"
     CDS             complement(4477..4962)
                     /locus_tag="VVR08_000931"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU6074869.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4965..6200)
                     /gene="fabF"
                     /locus_tag="VVR08_000932"
     CDS             complement(4965..6200)
                     /gene="fabF"
                     /locus_tag="VVR08_000932"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU6074870.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6222..6953)
                     /gene="fabG"
                     /locus_tag="VVR08_000933"
     CDS             complement(6222..6953)
                     /gene="fabG"
                     /locus_tag="VVR08_000933"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU6074871.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(6987..7907)
                     /gene="fabD"
                     /locus_tag="VVR08_000934"
     CDS             complement(6987..7907)
                     /gene="fabD"
                     /locus_tag="VVR08_000934"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU6074872.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7900..8874)
                     /gene="fabK"
                     /locus_tag="VVR08_000935"
     CDS             complement(7900..8874)
                     /gene="fabK"
                     /locus_tag="VVR08_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU6074873.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(8993..9217)
                     /locus_tag="VVR08_000936"
     CDS             complement(8993..9217)
                     /locus_tag="VVR08_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6074874.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9277..10251)
                     /locus_tag="VVR08_000937"
     CDS             complement(9277..10251)
                     /locus_tag="VVR08_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU6074875.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10251..10685)
                     /locus_tag="VVR08_000938"
     CDS             complement(10251..10685)
                     /locus_tag="VVR08_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6074876.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(10779..11564)
                     /locus_tag="VVR08_000939"
     CDS             complement(10779..11564)
                     /locus_tag="VVR08_000939"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU6074877.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11889..13253
                     /locus_tag="VVR08_000940"
     CDS             11889..13253
                     /locus_tag="VVR08_000940"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU6074878.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13256..13627
                     /locus_tag="VVR08_000941"
     CDS             13256..13627
                     /locus_tag="VVR08_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU6074879.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            13841..15115
                     /gene="serS"
                     /locus_tag="VVR08_000942"
     CDS             13841..15115
                     /gene="serS"
                     /locus_tag="VVR08_000942"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU6074880.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNAEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(15140..16039)
                     /locus_tag="VVR08_000943"
     CDS             complement(15140..16039)
                     /locus_tag="VVR08_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU6074881.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILNLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACTGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16149..16697)
                     /locus_tag="VVR08_000944"
     CDS             complement(16149..16697)
                     /locus_tag="VVR08_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU6074882.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTHQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16915..18237)
                     /locus_tag="VVR08_000945"
     CDS             complement(16915..18237)
                     /locus_tag="VVR08_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU6074883.1"
                     /translation="MLELLKSIDAFTWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVMSPVVIAETKKYFDK"
     regulatory      complement(18328..18416)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18579..20915)
                     /locus_tag="VVR08_000946"
     CDS             complement(18579..20915)
                     /locus_tag="VVR08_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU6074884.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELAFWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKAV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21019..21567)
                     /locus_tag="VVR08_000947"
     CDS             complement(21019..21567)
                     /locus_tag="VVR08_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU6074885.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEDQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSQKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(21564..21866)
                     /gene="zapA"
                     /locus_tag="VVR08_000948"
     CDS             complement(21564..21866)
                     /gene="zapA"
                     /locus_tag="VVR08_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU6074886.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21953..22834
                     /locus_tag="VVR08_000949"
     CDS             21953..22834
                     /locus_tag="VVR08_000949"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU6074887.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            22838..23452
                     /gene="lepB"
                     /locus_tag="VVR08_000950"
     CDS             22838..23452
                     /gene="lepB"
                     /locus_tag="VVR08_000950"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU6074888.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            23731..26097
                     /locus_tag="VVR08_000951"
     CDS             23731..26097
                     /locus_tag="VVR08_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU6074889.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGEQKSHHLETIQKHITTIEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDHAIQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWNRIPAMIGITDTDLKEIFGK"
     gene            complement(26145..27428)
                     /locus_tag="VVR08_000952"
     CDS             complement(26145..27428)
                     /locus_tag="VVR08_000952"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU6074890.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28214..29350)
                     /locus_tag="VVR08_000953"
     CDS             complement(28214..29350)
                     /locus_tag="VVR08_000953"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU6074891.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29412..29849)
                     /locus_tag="VVR08_000954"
     CDS             complement(29412..29849)
                     /locus_tag="VVR08_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6074892.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(29851..31806)
                     /locus_tag="VVR08_000955"
     CDS             complement(29851..31806)
                     /locus_tag="VVR08_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6074893.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIGVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(31830..33587)
                     /locus_tag="VVR08_000956"
     CDS             complement(31830..33587)
                     /locus_tag="VVR08_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU6074894.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKGQLVSTSVDAVVSTDSVEKIIFACDAGMGSSAM
                     GASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHVSVDN
                     FLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQGTAT
                     MGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNSQFLI
                     VDSLVTTPEYDKMAARMYK"
BASE COUNT        10002 a         7594 c         6387 g         9755 t
ORIGIN      
        1 aaaaaactat ggcagagaat cgttaatctc agattgtcgg tagaacgata aacaagggca
       61 aaaaagaaac caatcagact ataatataat aaactaattg gatctctgtg agatagtatc
      121 aaatggctaa tcccaaagat gatagcagat aggataacat ccaaatagta cttggactag
      181 ggaaagaagg tattcataaa ataccctcta tcaagagtct cctcaaaaac aggaccgatg
      241 attacaggca ggacaaaaga taagatagtc gataaaaagg ttggttgtcc atttgaaaaa
      301 agcacggtaa aatactcatc atgaatattc ctatgattaa tcaaatgagc atagcgtgcc
      361 caaaaattac cgagaatctg ataaaccaca taagttgcaa ataagtagaa gacaaatgac
      421 cagttccagc tctttttctc aaagataaag agcatctttt tcttttttaa cctccaaatt
      481 aatagaagga aacttcccac taatcccatt gttaaaataa gagaatagac atcagctcct
      541 aaccctaaaa tgatcgtcac atacaatcca attgtttgtg gtaaataggt agatagtaaa
      601 ataataagca aaaatattcc aaattgtctt agtttttttg tgtttctcat cgtacttttt
      661 tgaaagatta ccctgctcgg aagccgtact tccaagcatc tatataagaa ttaagtgccc
      721 cttgcctcat atagggagca aattctctat aatataacca tctactatat ccatcttccc
      781 aaacagcaag accacctgaa gtttgctcca agtcctcagt tgaaagaact gtaaatgtat
      841 ttgtacctgt cattgcaagt accttcttaa aatagattgt tgtaggctca catttatagt
      901 atatttcttt ttttgtctat tttatagccc atctcctcaa ctggcaattt ttcgacctga
      961 attacatttt tccataaaaa atgagacctt tctagtctca tttagtcatt cttagtattt
     1021 tctaaatcgt tgatagcgtt cttccagcaa ctcttctagc ggtttttgtg aaagtctagc
     1081 cagctccgtt tggagttctt ttttgacact cttaatcagt tctttactag aaagtcctat
     1141 ttcagaaatc accttatcca ccacgtccat ttctaacagt tcatgcgaag tgattttcat
     1201 cagttctgct gcttccatgg cgcgagtacc gtccttccat aaaatggaag caaagccttc
     1261 tggactgaga atggcataga tagaattttc cagcatccag acacggtccg cgacagctag
     1321 agccagagcc ccgcctgaac caccttcacc gataataatg gcgataatag gaactttcag
     1381 gtcactcatt tccatgagat tgcgagcgat agcttcccct tgaccacgtt cttctgctcc
     1441 gacaccagga taagcacctg ctgtattaat aaaggtcaca actggacggc caaatttctc
     1501 agcctgtttc atcaaccgca gtgcctttcg gtagccttct ggatgtggtt ggccaaaatt
     1561 ccgtttgagg ttgtcttgca aactcttgcc tttttggata ccaacaactg ttacagcttg
     1621 gtctccaagc caaccaatac caccaacaac tgcaccatca tcacgaaaag aacggtcacc
     1681 atgtaattgg ataaattcat caaaaatgcc tgtcgcaaag tccaaggttg tcaagcgact
     1741 ctgctcacgc gcttctctga ctatttttgc aatattcatc taggactccc tccatgcaat
     1801 ctgactaggc tagcaatcgt atctggtaag tctcttcttt tgacaatagc atccacaaag
     1861 ccatgttcta ataggaattc tgccttttgg aaatcctcag gcaagctttc acgaaccgta
     1921 ttttcaatca cacgacgccc agcaaaacca accaagctct gtggttcagc cagaatgata
     1981 tcgccttcca tagcgaaaga agctgtcaca ccaccagtcg ttggatctgt caaaatggtc
     2041 aggtaaaaga gaccagcatt tgaatgacgt ttaaccgccg cagagatctt agccatctgc
     2101 atgagactca tgattccttc ctgcatacgg gctccaccag aggctgtgaa taggacaact
     2161 ggcaattttt cgacagtcgc atactcaaac aaacgagtga ttttttcacc tacaaccgta
     2221 cccatagaag ccatgataaa gttagaatcc ataatcccaa gagccacagt ctgaccttta
     2281 ataagagcag ttcctgtcac aacggcttca tgcagacctg ttttttcacg catagatgcc
     2341 agtttctttt ggtaaccagg gaaatgcaag ggatccttgc tttcaatccc tgtaaacaat
     2401 tctttgaagg ttcccatatc aatcgtcaaa gccaagcgtt cttgggcaga aatacgaaag
     2461 gtatagctac agtgcggaca gatacgttca cttcccagat ccttctgata gatggtatgc
     2521 ttacagcctg gacactggga aaataattca tctggaacct ctggcttagc ttgaggtttt
     2581 tccctaaccg aacgattggg attgattcga atatacttat cttttttact aaatagagcc
     2641 attgattccc cttttcggtt taaactctta aagtcatttt attctttttc ttgatattta
     2701 ggtaagaagg tttccatcaa gaaggaagta tcataatccc cagcaatgac attgcgatct
     2761 gaaatgaggt caagctggaa atctgcattg gtctgcactc cttcaatctc taattcatag
     2821 agggcacgtt gcattttcat caaggcgtca aaacgatttt cgccgtgtac tatgattttg
     2881 gcaatcatac tatcataata aggcggaatg gtataacctg gataaactgc tgaatccacg
     2941 cgcaagccaa ctccaccact tggcagatag agattagtaa tcttacctgg acttggagca
     3001 aagttaaagg ctgggttttc tgcattgata cgacactcga tggcatgacc gcgtaggaca
     3061 atatcttctt gcttaacaga caaaggctga cctgccgcaa tgcaaatctg ttccttaacg
     3121 atatcaacac ctgaaacaaa ctctgttact ggatgttcta cctgaacacg agtattcatc
     3181 tccatgaaat agaaattgct acttgcttca tcaagaagaa attcaatggt tcctgcattc
     3241 tcatagccaa caaactctgc cgctcgaaca gcagcagcac ctatttcatg acgcagcgtt
     3301 tttccgattg caatcgaggg actttcttcc aaaacctttt ggttattcct ttgaagagaa
     3361 caatcccgct cacccaagtg aatcacatgt ccatgctcat cacctaggat ttgaacctca
     3421 atgtgccgag ctggatagat aacccgttct atgtacatgg caccattgcc ataattggcc
     3481 ttggcctcac tagaggcagt ttcaaaggca gaaacgaggt catctggttt ttcaacctta
     3541 cgaatccctt taccacctcc acctgctgaa gccttgagca taacaggata gccaattttt
     3601 tcagcaacaa tcaaagcttc ttcagagtta tgcacttctc catctgaacc tggtataaca
     3661 ggcacacctg ctttaatcat ctgagcacgc gcattgatct tatcccccat catatccata
     3721 acatgaccag atggaccgat aaacttgata cctacttctt cacacatggt cgcaaatttg
     3781 gaattttcac tgagaaatcc aaaaccaggg tgaatagctt ctgcctcagt caagactgca
     3841 gctgatagaa ctgcattaat attgagataa gactctgttg ccttgccagg accaatacaa
     3901 actgcttcat ctgccaaaag cgtatgaaga gcttccttat cagcagttga ataaaccgct
     3961 accgtcgcaa tccccaattc acgtgccgca cggataatac gaaccgcaat ttcaccacga
     4021 ttggcaatta aaatttttcg aaacatggag aacctcctta gttcccaatt gcaaaagtaa
     4081 ggataccact ggctgcaagc ttgccatcca cttcagcctt tgcttcaacc acagctatgg
     4141 tgccacgacg ttttacaaaa gtcgctgtca taaccaattg gtcgcctggt acaacttgct
     4201 tcttgaactt aaccttgtcc ataccagcgt aaaagaccag ttttccttta ttttcaggtt
     4261 ttgataactc caacacacca gcagtttgcg ccaaggcttc cataatcaga acacctggca
     4321 taactgggta ttgaggaaag tggccgttaa agaaaggttc gttaatggtc acatttttga
     4381 tagcaacaat ggtatcctcg ctcacttcca agacacggtc cactagaagc ataggataac
     4441 ggtggggaag agcttctttg attccttgaa tatcgatcat ttgatacgta ccaatccttt
     4501 accaaactca accatttctt cgttagagac gagaatttcc gttaccacac catccttagg
     4561 agctgggatt tcattcatga ctttcatggc ttcgataatt accaatgttt gacctttttt
     4621 gacactatca ccaactgtaa cgaaggcagg tttatctggt ccagcagcca agtaaaccac
     4681 tccaacaagt ggactctcta caagatttcc ctcactagcc acacttgctt cagctggagc
     4741 tggaacttcc tctgctacag tctctgctgg agcagatgta ggagctactg gactcggtgt
     4801 tgctagaacg ggtgctggag cgacttgagt tgcaacttca ggcacaggtc tcgcttcatt
     4861 cttgctaaac tgcaactcat ccgtcccatt tttataagaa aattctctca aacttgactg
     4921 gtcaaattga gtcatcaagt ctttaatatc gtttaaattc atacttatct attctcccaa
     4981 cgtttgaaag caagaactgc attgtggcct ccaaaaccaa aagtatttga aatagcgtat
     5041 ggaatttctt tctccaagcc ttgtccataa acgacattag cttcgatata atctgatact
     5101 tcacttgtcc cagctgtcat tggtacaaag ttatgacgca tagcttcgat ggtgacgata
     5161 gcttctactg cacccgcagc ccccagcaaa tgtcctgtaa aagacttggt tgatgataca
     5221 ggtacttcct taccaagaac agctacgata gcaccacttt ctcctttttc attggcagga
     5281 gttgacgttc cgtgagcatt gacataggct acttgctctg gagaaatctc agcttcttcc
     5341 aaggctagtt tgatggcctt gatagctccc tgaccttctg gatgtggaga agtcatgtgg
     5401 taggcatcac aagtatttcc gtaaccaacc acttcagcca ggatagtagc tccacgtttt
     5461 tcagcgtgtt caagactttc tagaaccaac atccctgaac cttcacccat aacaaaccca
     5521 ttgcgatcct tatcaaatgg gatcgaagca cgagttggat cctctgtagt agagagagct
     5581 gttaaggctt ggaatccagc gatggcaaaa ggtgtgatag aagcttctgt tcctcccacc
     5641 aacatcacat cttggaaacc aaacttaatg gagcggaagg catccccaat cgcatcattt
     5701 gatgaagagc aggcagtatt gatagattta caaacaccgt ttgcaccaaa acgcatggct
     5761 acattcccag aagccatatt tggtaaagct tttggaagag tcattggttt gacacgtttg
     5821 ggtccttttt catgaaggcg aagtacctga tcttcaattt ccttgattcc accaatacca
     5881 gatgcaacga taacaccaaa acgatcccta ttaagagcct ctacatcaag attggcatga
     5941 tttacagcct cttgggctgc atacaaggca tataaagaat agttatcaaa acggttggta
     6001 tcttttttta caaagtattt atcgaacgga aaatcttgga tttctgccgc attatgcaca
     6061 tcaaagtcac tatgatcaaa ttttgtaatg ccaccaatgc cgattttccc agttgctaaa
     6121 ctattccaaa attcttctgg tgtatttccg attggagatg ttactccata acctgttacc
     6181 actactcgat ttagtttcat tcttttcacc tctagctttc gctacatact taagccacca
     6241 tcaatggcaa ccacttgacc agttagataa tcttggcctg ctaaaaatac tgtcaaatct
     6301 gcaacctgct ctgcctgccc aaattctttc atcggaatct gagctagtgt agcttcctta
     6361 atcttatctg ataagatagc tgtcatatca gactcaatca ttcctggagc aatcacattg
     6421 actcgtatat tccgactagc gacctcgcgt gccacagact tggtaaagcc aatcaagcca
     6481 gccttagaag cagcatagtt agcttgacca atattcccca tcaaaccaac aacactagac
     6541 atattaatga tagcaccttc tctggctttc atcatcggtt tcaagactga ttgtgtcata
     6601 ttaaaggcac cagtcagatt gaccttgagc actttttcaa aatctgcttc tgtcatcttg
     6661 agcataagag tatcttgggt aatccctgca ttgttgacca aaacatctac tgaacccagt
     6721 tctgcaatag cttgatcaat catacgctta gcgtctgcaa aatctgatac atctcctgaa
     6781 atgggaacca ccttgatacc atagtttgaa aactcagcga gcaattcttc tgagattgcc
     6841 ccacgactgt ttaagacaat gttggctcct gcttgagcaa acttgtgggc gatggcaaga
     6901 ccaattccac gactcgaacc tgtaataaag atatttttat gttctagttt catttttttc
     6961 ctttcaaaac ttctacttat tttagtctat ttttctaaaa gtgctactaa actcgcttga
     7021 tcttccacat gagctaagtg agcagtttga tcaatttttt taacaaaacc tgacaagact
     7081 ttccccggtc caatctcgat aaagttgctt atgcctgctt cttgcatgac cccaatactt
     7141 tcatagaaac gaacgggttc cttgacctga cgcgtcaaga gctgagcaat gtcctctttt
     7201 tgcatcacag cagcttctgt attgccgact aggggacaag taaaatctga aaaacttacc
     7261 tgagctagag tttcagctag tttctggcta gcaggctcaa ggagagcggt gtgaaaggga
     7321 cctgacacct taagaggaat caagcgtttg gcacctgctt cttgcaaaag ttcaaccgct
     7381 cgatcaactg caaccacttc tccagcaatg acgatttgtg caggtgtgtt atagttggct
     7441 ggagtaacca ctccaagttc agaagctttt tgacaggctt cttcaatgac ctctactggc
     7501 gtattgagaa ctgctaccat cttgccagag tcagcaggag ccgcttcttc catataggct
     7561 ccacgcttag ctaccaaggc aaccgcatct tcaaaatcca aggcgccgct tgccaccaag
     7621 gcagagtatt ctccaagaga caaaccagca accatatcag gctgatagcc cttttcttgc
     7681 aataaacggt agatagcaac cgaagtcgct agaatggctg gttgcgtata gcgggtctga
     7741 ttgagtttgt cttcttccgt atcgatgaga taacgtaaat cataaccgag cacctgactc
     7801 gctcgatcaa tcgtttcttt gacaatcgga tactgatcat agaaatcccg tcccatccct
     7861 agatactggg caccttgacc agcaaataaa aaggctgttt tagtcatttc ttacaactcc
     7921 tgcccagcga gaggcttctt cttgaatttt cttagcggct ccgtaataca aatcttttag
     7981 gatttcttca gctgtttctt ctttagaaac aagccctgcg atttgacctg ccatgacaga
     8041 gccaccatcc acatcaccgt gaacaactgc tttggctagg gcacctgctc ccatttgttc
     8101 aaagatttct aaatcaggat cttcctgctt aaaggcatct ttttcagcca gttcaaaatc
     8161 tctagtcaac tgatttttaa tagcacgaac agcatgacca aagtgctgag ctgaaatcgt
     8221 agtatcaata tcccttgctt ttaaaatttt ctccttgtag tttggatggg cattcgactc
     8281 ttttgcaact acaaaccgtg tccccacctg tacagcctct gcacctagca taaagccagc
     8341 cgcagcacct tcaccatccg caattcctcc tgcagcaata acaggaatag atatagctgt
     8401 ggctacctgt cgcaccaagg tcatggttgt taatttaccg atatgccccc cagcttccat
     8461 tccttctgca ataacagcgt ctgcaccgat tttttccatg cgtttagcta aagcgacact
     8521 aggaacaaca ggaataacga ttatcccagc ttcatggaaa cgttccatat acttgcttgg
     8581 atttcctgct cctgttgtga caactttaac accttcttca ataacgagat ccacgatatc
     8641 ttccacaaag ggagataaga gcatgatgtt gaccccaaag ggtttatcag tcaatgattt
     8701 gattttatca atattggcct tgacaacttc tttcggggca tttcccccac cgataattcc
     8761 taatcctcca gccttggaaa cagcccctgc caaatcacca tcagcaaccc aggccatccc
     8821 tccttggaaa ataggatagt caatcttcaa taattctgta atacgcgttt tcatagtgcc
     8881 tccaaccttc cttgcttacg taatagttcg atttcaccat aatttgacag tcaaactatt
     8941 acctaaacaa gagggagtgg gtttctccct actccttcta ctaatattct gcttattttg
     9001 cttgctcttc aacgtaagca accaagtcac caactgtttt caagtcattt tctgcttcga
     9061 tttggatatc aaaagcatct tcgatttctg agattacttg gaacaagtcc aatgaatctg
     9121 cgtccaaatc atcaaaagtt gattcaagtg ttacttctga tgcgtctttt ccaagttctt
     9181 caacgataat ttcttgtact ttttcaaata ctgccatgat aggactcctt taaaataaat
     9241 agttttttta taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc
     9301 ccaggtcaag cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat
     9361 gagaccttgt tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc
     9421 atattccatc atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt
     9481 atccaaaata cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat
     9541 aggagattca tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa
     9601 gactgtgcgt ccatccatct tcaaaaacga atctgcactt tcttgatctg aaaatggaga
     9661 atgcaaacct gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact
     9721 ctcagctaag aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc
     9781 aaacaacaca gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc
     9841 aatcaccaag cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc
     9901 aaatacaaat ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcgccaat
     9961 attagcttga acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag
    10021 gatgataaaa tccagttctt ttcctgttat tccagctttt gccatcagtt tcttagcaac
    10081 ctctgtagcc aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt
    10141 tcgacttgaa atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac
    10201 cacttgctct ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa
    10261 tcctccaaaa attggtaaag attagtcaag cctttaccca tgacagcaat ttcttcctcg
    10321 ctcatgccat caataatttt ttctaccatg gccttgtgga agcgtttatg cagtctatga
    10381 atcaagcgac ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga
    10441 actcgctcaa tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga
    10501 gttaccatca actcttttga cacttgactt ggagtcacat ctggagcctt accgatgaca
    10561 tcaatcgtat gcatttcttt gatggagata tccttaaaac gactacctct caagttcact
    10621 tcctcaatta caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag
    10681 tccatttttc atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa
    10741 gaattatatc aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt
    10801 cttcttctct ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat
    10861 ttctgtaggt tcagttctaa agtagcgtaa ccctgccagt ctttaaactg gctctcccaa
    10921 accaacttct taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc
    10981 tgttctctcg tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct
    11041 agggcttttt ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca
    11101 ccgatactgc ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca
    11161 aaggcttgga taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata
    11221 ttcgctgcgg cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc
    11281 ttgattttat aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca
    11341 tcctcatcca ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca
    11401 ttggcattga ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct
    11461 aaaatctcct cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta
    11521 aggattgcca agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat
    11581 tttataagca gtttatactc ttcgaaaatc tctttaaacc gcgtcagctt ccatctgcaa
    11641 cctcaaaaca gtattttgag ctgacttcgg ctagcttcct agtttgctct ttgattttca
    11701 ttgagtgtta aattatttca ctgtcaaagt atatcttttt taggagcaga aagcaagaaa
    11761 aaatcgactg aaagtgtctc agccgataag aaaggctcgc tttaggctag aaagcatctt
    11821 attttcttca ttgaaaaaag cctttctttc tgctataatc gtataaaata cttactttag
    11881 gagttcttat gaaagttgtt aaatttggag gtagttctct tgcctctgct agtcaattag
    11941 aaaaagtttt aaacatcgtc aaaagcgatt cagagcgtcg ttttgtagtc gtttctgcgc
    12001 ctggtaaacg caatgctgaa gatactaagg ttacggatgc cctgattaaa tactaccgcg
    12061 actatgttgc gggtaacgat attagcaaga gccaaagctg gattatcgac cgctatgctg
    12121 ctatggttag tgaattggga ctaaaaccag ctgtgctaga aaaaatttct aaaagcattc
    12181 acgccttggc cactcttcct attgaagaaa atgaatttct ctacgatact ttcctagcag
    12241 ccggtgaaaa taacaatgcc aaattgattg ctgcctactt taaccaaaat ggtatcgatg
    12301 cacgctatat gcaccctaga gaagctggga ttgtggtcac aagtgaacct ggtcacgctc
    12361 gcatcattcc atcaagttat gacaagattg aagaattgac aaacaccaat gaagtccttg
    12421 tcattcctgg tttctttggt gtcactaagg aaaatcaaat ctgtactttc tcacgtggag
    12481 gttctgatat tacaggttct atcattgctg ctggtgtcaa agctgacctc tatgaaaact
    12541 ttacggacgt tgatggtatc tttgcagccc accctggtat tatccaccaa ccacactcga
    12601 ttcctgagtt gacctaccgt gaaatgcgcg agttggccta tgcaggcttc tcagtccttc
    12661 atgacgaggc tcttcttcct gcctaccgtg gaaaaattcc tctggttatc aagaatacca
    12721 acaaccctga ccatccaggt actcgtatcg ttctaaaaca cagtaatgat gaatttccag
    12781 ttgtgggaat tgctggtgac tcaggctttg tcagcattaa catgtcgaaa tacctcatga
    12841 accgtgaggt tggatttggc cgcaaggttc tgcaaatcct ggaagaactt aacatcggtt
    12901 gggaacatat gccaacaggt atcgacgatc tttctatcat tctccgttct cgccaactaa
    12961 ctcccatcaa ggaagaagaa atcctgcgtc agttggttca aaaggctaaa gtagatcatg
    13021 cagaaatcga acacgacctt tctatcatta tgattgttgg tgaaaaaatg aagagccaca
    13081 tcggagtgac tgctactgcg acacgcgctc tatctgaaaa caaaatcaac atccagatga
    13141 tgtctcaagg ttctagtgaa gtttctatta tgtttgttgt caataaagac caagagaaag
    13201 cagcaattaa agccctctac aatgcctttt ttggagaaag taaggaagac taagcatggc
    13261 ccaatcactt aacaaaacag tactcctcag tacgacaggc acttcctacc tctctatcgc
    13321 tgggaaagtt gggaaattcc ttgtcggaga tcaggctttg gaattttacc cagatgtcaa
    13381 tgtcgaacaa tttatccaga ttccttggag ccatatcaat cagattggag ccaatgtcac
    13441 tggatgcaaa atcagccgcc acttcgaagt ctttacagac aaaggaaaat tcctctttgc
    13501 ttcaaaagac tcaggtgcca ttctcaaaat tgcacgcgaa aaactaggca atgacaaggt
    13561 cgtcaaactt ccgaccctga ttcagacaat tagccaaaaa tttaaaaatc tatttgcaaa
    13621 aaagtagaaa ctttagtata atcatagcaa cggataagta ggttatcttc ttctttcaga
    13681 aagtctgcgg gtactgcgag cagataggag ggataggtga aattctaccg ttagtaacaa
    13741 ttacatacac aatcaagtgc acacctgtga agttggatgg aaccgtggcc ctgccactcc
    13801 aacgtcttgt caggtgtgct tttttcataa aggagttctt atgttagata tcaaacgtat
    13861 tcgtacagat tttgaagctg tcgcagaaaa attagctaca cgtggtgtag atgctgctgt
    13921 cttgaatgaa atgaaagaaa tcgatgctaa acgtcgtaac atcttggtca aggttgaaac
    13981 tctcaaagca gaacgtaaca cagtttctgc tgagattgcc caagctaagc gcaacaagga
    14041 aaatacagat gacaagattg ctgccatgca aaatctatct gctgaggtta aagccttgga
    14101 tgctgaattg gcagaaatcg atgctaaatt gacagaattt acaacgactc ttccaaatat
    14161 cccagctgac agcgttcctg ttggggctga cgaagacgac aatgtggaag ttcgccgttg
    14221 gggtactcca cgcgagtttg acttcgaacc taaagctcac tgggatctcg gtgaagacct
    14281 tggtatcctt gactgggaac gcggtggtaa ggtaacaggc gctcgcttcc tcttctataa
    14341 aggcctcggt gctcgtttgg aacgtgctat ctacaacttt atgttggatg aacatggaaa
    14401 agaaggctat actgaagtca tcacacctta catagtcaac catgattcta tgtttggtac
    14461 tggtcagtat ccaaaattta aggaagatac ttttgaactc agcgatacca actttgtctt
    14521 gattccaact gctgaagttc ctctgacaaa ctactaccgt gatgaaatct tagacggcaa
    14581 agatcttcca atctacttca ctgctatgag tccgtcattc cgttctgagg ctggttctgc
    14641 cggtcgtgat acgcgtggct tgatccgttt gcaccaattc cacaaggttg aaatggtcaa
    14701 atttgccaaa ccagaagaat cttacgaaga attggaaaaa atgacagcca acgctgaaaa
    14761 cattcttcaa aaactcaacc ttccataccg tgtcgttgct ctctctactg gagatatggg
    14821 cttctcagct gcgaagactt acgacttgga agtgtggatt ccagcacaaa acaattaccg
    14881 tgaaatctca agctgttcaa acgcagaaga tttccaagcc cgtcgtgccc aaatccgtta
    14941 ccgtgatgaa gcagatggca aggtgaaact ccttcatacc ttgaacggtt ctggacttgc
    15001 agttggacgt acagtggctg caattcttga aaattaccaa aatgaagatg gttctgtgac
    15061 catcccagaa gcacttcgtc catacatggg tggagctgaa gtcatcaaac cataaaaaat
    15121 aaggtttagc tatttctagc tagacctttt ttcgtaacca aatcagataa gcacctagta
    15181 caaagaataa aatagttagg catataatgg tttcagccaa taccaggtaa tccagaaatg
    15241 gaagtttcaa aattccctga gccatcttga gcgaggtcgc tgtgataatg gttgggaagg
    15301 tgagggctga gaaggctggt tgaaaacctt gttttaaaat gttgggcaga cgagttaaaa
    15361 caaagaaaaa gaaggattga gaagccaaaa tcatgacaat caagacccaa gtcggcaggc
    15421 tggttcctcc tactcgaact agagaagcca agagtagaga gaaaggagca cagtagattc
    15481 cttcttgtcc aagcaaggct agtgggagtg gatgtttctt taaatcgcta taaataaggg
    15541 gatagagata gaaggtcaag agaaaaccaa aactcaaggt cgcataggca atttcgataa
    15601 tacctaccag aggataggtc aaggcagcca ctgctatccc cacatagaga accgtccagc
    15661 ttggagtggc atgaaccctc cgccctgtac aagcaaactt gatggtaaaa ccagcaatca
    15721 aggtcaaatc caagagaaat gaaaaccacc aaatcccttg tgctaccaaa ggaagataag
    15781 agaatacgcg aaagacatag gtcgataaaa tcatcccagc cataggaaag gttgccattc
    15841 ctgacaaaag agggggcttg gtcaattctt gcttggtttc tttccaatta aagagattca
    15901 gaattagaaa gtaaatccat aaaaccaaac cagtcagact aaaaagatgg gatagaaccg
    15961 gcaacgtatc taaaataaga tttccagctc ctgccaaacc tagcaaacaa cctgaaaata
    16021 ctaaggggag ttttttcatc ctaacctcca ataatcatgt tagtttcagt ataacataaa
    16081 agcgcttaaa tgaggattta aaaaaacgaa gtccgcttat ttcagacttc attttactca
    16141 gatatgaatt aggcataagg ttgcaattct ggattaattg gtgtattagc taagttgttg
    16201 gcatagttac agaggattgc taggctgaca ccaaaaacca catccaaggc attttggtga
    16261 gtgtagccag cttctaaaaa ctcagacaag gcttcatctc ctacacgacc cttggtattg
    16321 ataactgcca aggtaaactt agctagggta tccaatttag gatctgtttc aattggagta
    16381 cgattgcgaa gagcttgaat caagtcatca ttcatctgga tttgtttgat ggaaaaggct
    16441 gtgtgacctg cgacacagaa ggcacaacca ttggtcacgg ctgccgtgat ttgcaccact
    16501 tcacgctcaa cgggtgtcag gctgttgcgg cggtggatag atgagacaat ttggtaggct
    16561 tctaaaacag tcggggcatt ggccaagaga ccgattaggt tgggaatata gccattgttg
    16621 tctttttcta ctgtttcaag aatttctttc acttctgctg gtgctgactc tactgtatgg
    16681 atagtaaatg ttgtcataag atacctcttt tcttattatt gacactaata ttattggaaa
    16741 atcttataaa atcctgattc ctaagtttat ctaagataaa gctttattct ctcataagat
    16801 tttcgttgtt atattagttt atcacactta caatcacttg tataatatat attatatatc
    16861 aggctgataa aaattattta taggcaaaaa aatcacacga gctgtgtgat tccattattt
    16921 gtcaaaatac tttttagttt cagcaataac gactggcgac atgaccaaga gggcaatcaa
    16981 gtttggcaga gccatcaagg cgttaacgat atctgcgata atccagacca tatccaactc
    17041 gataaatcct cctaacaaga ccatgagcac aaaaaccaca cggtagagcc agataaagcg
    17101 aaccccaaag aggaactcaa aacagcgttc tccgtaatag ttccaaccta gaatcgttgt
    17161 aaaggcaaaa agtacaagga agatggtcaa gagggcaggc ccaaagtgtg aaaagactgt
    17221 tgagaaagct gactgagtca aggcaacccc attcaagtca ccactccaaa ctccagttac
    17281 caagatggtc aaaccagtta gagtacaaat gatgagggta tcaataaagg ttcctgtcat
    17341 ggaaatcaaa ccttgctcta ctggttcatt tgtcttggca gctgcagctg caataggagc
    17401 agaacccaga ccagattcgt ttgagaacac accacgcgcc acaccatttt gaatagccat
    17461 ccgaacgcta gcaccagcaa atccacctac cgcagcaagg ggactaaaag ctgaggtaaa
    17521 gactaaagcg attgtgccag ggatttttcc gatattaaag aaaataactg taagagttcc
    17581 taagatataa atgagggcca taaaaggaac aacagtagtt gaaaccttag aaatagactt
    17641 gagtccacca aagactgcaa tcgctacaaa gacagacaag acgagagctg tgatggctgg
    17701 cgaaatcgtc gttgtatttt ggatagattc tgtaatcgag ttgacttggg tgaaggttcc
    17761 gattcccaag agagcaacca atactcctgc tactgcaaac aaaacagcaa gtggtcgcca
    17821 cttttctccc atccctagaa ggatatagtg catgggacct cccgctactg caccatggtc
    17881 gtccttggtg cggtatttga tggccaagag tccttccgca tacttggtag ccattccaaa
    17941 gaaagccgcc atccacatcc aaaatagagc tcctggtcca ccaaccttga tcgccgtcgc
    18001 aactcctatg atatttcctg ttccaacagt tgatgccaag gctgtacaca gagctgcaaa
    18061 actggataca tcaccatgtc ccttatcctg gataaaaata agctgaaagg ccttgggcag
    18121 acgcaaaacc tgcaagagtc ctagccgcat ggttaggtaa atccctgttc cgaccaataa
    18181 aatcaagagg ggcggtcccc aagtaaaagc atcgattgat ttaagcaatt ctaacatttc
    18241 cttctcctat cgtttcaacc ccaaaagaaa gagcacatgc aagatacatg tactctggaa
    18301 tgcttagata aatgctaaaa agcggtctat cctagctctg tccttttacc tgagagtttg
    18361 agcagttgcc tgccttgccc cttcggtgcc tttacggtct ctccagagtt ccgtccattt
    18421 acagtcatgg aaaatcaaac gattccccac ttctattaaa cttcattcgg tgttggtatt
    18481 aattgattct aattttacaa aaaatgttgg cttttgtcaa tgtgtttatt agtaaaaatt
    18541 agttcaacag tttttacttt ataaagtcca gaatactgct atcctttaaa agtgacaata
    18601 gtcgcaccac tgcctccagc attttgtggg gcatagccga aactcttgac atgtttgttt
    18661 ctttgcaagt atttggtaac tccttcacgg atgactcctg ttccgatacc atggatgata
    18721 tcaacttgag ccatattgtt aagcaaggct tggtcgatga aggtatctag ctcattcatg
    18781 gcttcttcat agcgcttgcc tcgaagatcc agtctagctt gaggtcctcg cccagaagtt
    18841 cgtttcacaa cattgacctg tttcttcttg actgcttttt cttgctgggc ttgaacaaga
    18901 tcaaactctt tctcttccaa ggtcatctta atcaagccaa cttgggcttc ccagcggccg
    18961 tccttgagtt gactggtcaa ggtaccacgc tgaccataac tgagaaccac gatatcatct
    19021 cccacctttg gagctcgttt tttcttggcc ttttgaagga ccttgttttt agacaagtcc
    19081 actttttcag gagccaattt tttcaacttg gccttggctt caatgatttc gtggggcttg
    19141 agttgggatt tactgtggag atttttgaga atctggtcac tttcacttag ggccatatcc
    19201 acaatctcag cagcctgttc acgcgccttg ttaagctcgg tttccttttc acgattaagc
    19261 tcgttgtaga gtttttttag cgcacggttc atcttgagat tttcttgctc cacctcacgg
    19321 atattgtcca agcgtttgcg gctttccagc gtctgctctt ctaattgctc aatgatacga
    19381 ttgacgtcat tgtcctgatc gatctgctga ctggcatctc ctacgataac ttcagatagg
    19441 cctagacgtt tggcaatttc aaaggcatta cttcggccag gaacaccctg cataaagcga
    19501 taggtcgggc gaagagttgc agtatcaaac tccatactgg cattttgcac aaaggctgtc
    19561 tcaataccgt aggccttgag ttctggatag tgggtcgtcg ccatggtctt gatttgacgc
    19621 aggcgaaggt cctccagaat agccatggca agggctgctc cctcttgggg atcagtacca
    19681 gcccccaact catccaaaag taagagtgaa tgttggttga ccttaccaag aatatccacg
    19741 atattggtca tatggctaga gaaggtagac aagctctgct caatagactg ctcatctcca
    19801 atatcagcaa agatttcttc aaaaatacca acacgacttc ccttgtctgc taaaatcggc
    19861 aatcctgact gggccatgac ctgtgtcaag cccagagttt tgagcatgat ggtcttccca
    19921 cctgtattgg gacctgtaat gacaatagct gttaaatctt gaccaaaatg gacatcattt
    19981 gcgacggcat ttttgaccaa aggatggcag acatggagca gttgaatctc ttgattttct
    20041 gacagctgag gcacgactgc ttgtctttct tggataaatc gaaccttggc acgaatcaag
    20101 tccagatgac cgataatcca agcgtcatta gcaatctcag ccgcatgagg gcggacacgc
    20161 tcagaaattt cttggagaat gcgaagcatt tcatagcgct catctgctcg cagactagca
    20221 atttcttcgc tcagtttgac tacctcacgt ggttcgatat agacggtgtt tccactagca
    20281 gaaatatcat gaacgacacc tgcaatctta ttgcggtagg tgtttttgac tggtaaaacc
    20341 tgacggccat ttctgctagc aacaattcct tccgtcaaca tctgcgcttt ttgcttgagc
    20401 aagtcttgta aaacatcgcg tacctgactc tcgctatcat gtatttttcg acggattcgc
    20461 gccaattctt cactggcaaa attttcaatg aaacccgcat cattaaaggc ctgaagattt
    20521 ccttgtaatt gcggaaaatc atgtaatttc tcaaaccaaa aggctaattc ttccaagctg
    20581 acattttcca gattggcgta aaaactttga agttctcggc tggcaagaag cacgcgtttc
    20641 aagagtagga actcctcgat attgagatcc gctcccatct ccaacctctt gcagactcct
    20701 gcaatttcct tagttgagag aatagtaaaa tgcggttgct cgacgaaaag agcctgcatt
    20761 tccttcatct cagcaaaagc ctgtttgatt ttatctgctt tggcagtcgg agccagttgt
    20821 ctcaattgct ccaagccctg ctcggtcaac aaatgaggct caaacaaggc cttgacctta
    20881 tcgaactcta atgtttctaa tattttctta ttcatcttta tttccttgtc tttgaatgtc
    20941 taggtgtggt agctttttac attctgatag attcgagtca aatctgtaaa caaagggcta
    21001 ggaaaactcc tgcccttttt atccgattaa atttgtcacc cagatttgtt tgagccaact
    21061 ggttgttatc ggtatgctct ggatgatgtg ttttgcgacg atactctttt caagaggatt
    21121 ttgtataact gccatgggga tggtcgccaa gattgtcaag gccatttgca agacaaataa
    21181 ggtcaccaac atggacaaga tacctgctga aacttggaac aacttaccac ccagtttttg
    21241 gctaggaatc aagtgtaaga gaagaccaag caaacgacca atgctataga caatcccaaa
    21301 tacaagcaag tagccgatac ctgcataaaa gaccttatcc agctgaaaga gttgatccga
    21361 tgggaaaaag aaagtcccct gatcttcctg cgaatttgca taagggagca ataaatggaa
    21421 ttgctctcca agccccttat aaaactggcc agccataaaa gccgatgcca tggctgaaat
    21481 caggtaataa acctgtaaga gcaggcctct ccgatagccg atataaaatc cccaaaccaa
    21541 gaccaataga agaaggaatg aaatcataag gaatcctcaa tcttgctctg ttcttgctta
    21601 caagtcacaa gcttgtgacg gagttcttct agctcttgct ccttatcgtc aaattcaatc
    21661 tcacggctga gctgagttga taaacagttg actgccaaca aaagagcgat tgtttcatca
    21721 tctgcgctag gcatttgttc tttaattgct tggtattttt ctgtcgcaac cttagcgatt
    21781 tcctccataa aaaggttatc atgttcgctt gtcaaggtta acgatttttt cccgaatgta
    21841 aatttgaatc gatttagatt tgccataaaa ttcacctcac gatattatac caaaattcgc
    21901 taattttgtc agtttttaca aattttactg cttttgtggt acaatagaaa ctatggcaag
    21961 tatcacactc acaccaagcg aaaaggatat tcaggctttt cttgaacact atcaaaccag
    22021 tctggctcct agcaagaatc cctatatccg ctactttttg aaactacctc aagcaacggt
    22081 ttctatctat acttctggaa aaatcttgct tcagggtgaa ggggctgaaa aatacgccag
    22141 tttctttggc tatcaagctg tagagcaaac cagcggacaa aatcttcctt taattgggac
    22201 agatgaggtg ggaaatggtt cctactttgg tgggcttgca gttgtggctg cctttgtcac
    22261 acctgaccag cacgactttt tacgaaaact cggtgtgggg gattctaaga ctctgaccga
    22321 ccaaaagatc cgtcagattg ctcctattct caaggaaaaa atccagcacc aggcactcct
    22381 tctctcaccc agcaagtaca acgaggtcat cggagaccgc tacaatgctg tttcggttaa
    22441 ggttgccctc cataatcagg ctatctatct cctccttcaa aaaggtgttc agcctgagaa
    22501 aattgtgatt gatgccttta ccagtgctaa aaattatgac aagtacttgg cacaagagac
    22561 caatcgtttc agcaatccta tcagcttaga agaaaaggct gagggcaaat acttggctgt
    22621 cgcagtttct tctgtcattg cgcgtgatct ctttctggaa aatcttgaaa atttgggacg
    22681 agaactgggt tatcagcttc caagtggagc tggaacggct tctgacaagg tggctagcca
    22741 gattttgcaa gcctatggta tgcagggact cagcttctgc gccaaattgc actttaaaaa
    22801 cactgaaaaa gcgaaaaaac gcttagaaag gtaagttatg aattcattta aaaatttctt
    22861 aaaagagtgg ggattgttcc tcctaattct gtcattacta gctttaagtc gtatcttttt
    22921 ttggagcaat gttcgcgtag aaggacattc catggatccg accctagcgg atggcgaaat
    22981 tctcttcgtt gtaaaacacc ttcctattga ccgttttgat atcgtggtgg cccatgagga
    23041 agatgggaat aaggacatcg tcaagcgcgt gattggaatg cctggcgaca ccattcgtta
    23101 cgaaaatgat aaactctaca tcaatgacaa agaaacggac gagccttatc tagcagacta
    23161 tatcaaacgc ttcaaggatg acaaactcca aagcacttac tcaggcaagg gctttgaagg
    23221 aaataaagga actttcttta gaagtatcgc tcaaaaagct caagccttca cagttgatgt
    23281 caactacaac accaacttta gctttactgt tccagaagga gaataccttc tcctcggaga
    23341 tgaccgcttg gtttcgagcg acagccgcca cgtaggtacc ttcaaagcaa aagatatcac
    23401 aggggaagct aaattccgct tatggccaat cacccgtatc ggaacatttt aagaaaccta
    23461 agaggccgag aatcaccaat ctcagcctct tcttctatcg tgagaagtga ttgtttattt
    23521 acaaatactc aatgaaaatc aaagaacaaa ctaggaagct agccgtaggc tgcttaaaac
    23581 agtgttttga ggttgtggat agaactgacg aagtcagctc aaaatactgt tttgaggttg
    23641 cagatggaag ctgacgtggt ttgaagatat tttcgaagag tataaaataa aaacaatccc
    23701 aactctcacc tattcatgca aaggaatttt atggaagttt atttttcagg aaccattgaa
    23761 cggattattt ttgaaaatcc cagcaatttt tatcgcatcc tcctcctaga aatcgacgat
    23821 acggacgcag aggattttga tgactttgaa atcattgtca caggaaccat ggctgatgta
    23881 attgagggcg aagactatac tttttggggg caaattgtcc agcactccaa gtatggagaa
    23941 caactgcaaa tcagtcgtta tgatcgcgca aaaccaacta gtaagggctt ggtcaagtac
    24001 ttttcaagta gccatttcaa ggggattggt ctcaagacag ctcaaaaaat cgtagatacc
    24061 tatggcgaaa ataccattga tgaaattttg caacacccag aaaagttaga aggcatcgca
    24121 ggactctctg ccaaaaatcg cgaggctttc gtctccactc tccgtctcaa ctacggaacg
    24181 gagatggttt tggccaaact agccaactac ggcattccca acaaactagc ctttcagatt
    24241 caagactttt acaaggaaga aacccttgat gtggttgaaa attatcccta ccagctagtt
    24301 gaggatatca agggtttggg ctttaccatt gctgaccaac tagctgagga actaggcatc
    24361 gaaagtcagg ctcctgaacg cttccgcgcc ggtctagttc acagtctttt tcaggcctgt
    24421 atggaaacag gggacaccta tgttgaagca cgggatttgc tggaacaaac ccttactctc
    24481 cttgagtctt cccgtcccgt ggaactagac cccagtcaag ttgcccaaga gctctcctac
    24541 ctgatcgaag aagacaaggt tcagcagatt gataccaaga tctttgacaa cagcctcttt
    24601 ttcgctgagg aaggcatccg cagtcacttg gttcgtatcc ttgaaaaagg agaacagaag
    24661 agtcatcatt tagaaaccat tcaaaaacat atcactacta tcgagcaaga gctgggaatt
    24721 gagtatgata acattcaaaa acaggctatc tgtgatgcta tccagaataa ggtctttatc
    24781 ctgacaggtg gacctggtac tggtaagaca actgttatca atgggatcat cgctgtttac
    24841 gccctgttag agggacttga cctcaggaag aaaagcaatc tgcccattct tcttgctgct
    24901 ccaactggac gagccgctcg ccgcatgaat gaattgacag gtttgcctag cgcgaccata
    24961 caccgccact tgggaatgac aggtgacgat gataccagtc atctggaaga ttacctagat
    25021 gctgacttta tcatcgtgga tgaattctct atggtagata cttggctggc caatcaactc
    25081 ttctccaata tctcttctaa cagtaagatc ctcatcgtag gtgacagtga tcagctacct
    25141 tctgtcagtc ctggacaggt tctagcggat ctgcttcata ttcctttgat tcctcagact
    25201 cgcttggaaa aaatttatcg acaaagcaaa gaatcaacca tcgtcaccct agctagtcag
    25261 attcgacagg gcatcttgcc agctgatttc acccaaaaaa aagctgaccg ttcctacttt
    25321 gaaattgcta gtggccatat tcctgccacc attgaaaaaa tcttaggtgc tgccctcaga
    25381 aatggtattc ctgcccgtga tatccaagtt ctggctccta tgtaccgagg gacggcaggg
    25441 attgatgcta tcaatcagct catgcaagac ctgctcaatc ccccacaaaa agatcaactc
    25501 agttttgaag ctcctcagtg ccactatcgt aagagagaca aggtcattca tttggttaac
    25561 gatgctgaaa tcaatgtctt taatggggat ttaggagcta tcacagacct gattcctggt
    25621 aaatacaccg aatcgaaaca agacgagatt gtcattgatt ttgatggtaa tgaagtctct
    25681 tacccccgta acgaatggta caagattcgc ttggcctatg ccatgagtat tcataagtct
    25741 cagggaagtg agttcccagt tgtcatccta ccgattacta gtgctagccg acgtatgctg
    25801 gagcgaaatc tcatctacac agccattaca cgtgccaaaa gcaaactcat cttactaggc
    25861 gaattacaag ccttcgacca tgctatccaa cacatcggaa ctgcccgaaa aacctatctg
    25921 attgaacgct tcagtgatct actggagaat gttgaagaaa agcaacaagc tgtctctgaa
    25981 acagtcacat caagtgcctc tgaacaatcc tacatcctaa ccgaagaaaa ctggaaccgc
    26041 atcccagcca tgattgggat tacagacaca gacctcaaag agatttttgg aaaatagtgc
    26101 atcagaaaac ccaccaattc aggtgggttt tctgtttatt aagattattt tactgttgct
    26161 gtgcttgtaa tcaattcaac agcttttttg attgtgatat catgtttcaa catgtcagct
    26221 gaaagcaagc tttgtacttg agcaacttcc atgttgtagt ctgctgccaa ttgctcaact
    26281 tctttttgga tttcttcttc tgaagcatca aatccttcag ctttggcaac tgcttcgata
    26341 acaaggttag tcttagtacg tgactcagct tctgcttggt attggttgtg aaggtcttct
    26401 tgagtagttc cagtgatttg gaagtacatg tcagggttga tcccttgacg ttgcaagttc
    26461 ccaaggaatt catttactga acggtgaact tcttcgtgga tcatttcttc tggaagttct
    26521 acgatttcag cgttttctac agctgtatca attgctgcac cttcaactgc atctttgtaa
    26581 gcttcttctt tagcagcagc caattctttg cggtattttt ctttcaagtc agcaagtgtt
    26641 tcaacttctt catcaatgtc ttttgcaagt tcatcgtcaa gagctggaac ttctttagct
    26701 tttacttcgt ggatagttgt cacgaattta gcttctttac ctgcaaggtc ttctgcttgg
    26761 tagtcttctg ggaatgttac gataacatca acggtttcgc cagctgagtg acctaccaat
    26821 tggtcttcga aaccagggat gaattgacct gaaccaagtc caagtgagaa gttttcacct
    26881 tttccgccgt caaattcaac accgtcgata gaaccaacga agtcgatcac aacagtgtcg
    26941 ccgttttcag cagcagcttc cttgataacc aattcagcca ggttgttgcg ttcgcgttcg
    27001 atacgctctt caacatcagc gtcagttact tctttttcta catcaactga tacttcaagg
    27061 tttttgtagt cacccaattt tacttcaggt tttgtaacga cttcagcagc gataacccag
    27121 tcttgacctt tttccattga agttacgtca atttttggtt gggcaaccac ttcaagacca
    27181 gcttctttta cagctgcttc ataagcgttt ggcaaaagag cgttcataac gtcttggtaa
    27241 agtgattctt caccaaattt tttatcgaag ataggacgtg gaaggtgacc tttacggaaa
    27301 cctggaacat taagagattt cttcactgac ttgaagacac ggtccaattc tggtttgatt
    27361 tggtcttgag agatagtgaa agtcaagaca ccacggtttg tttctttgtt ttcaaatgat
    27421 acagacattc tgtcatttct ccttaaaatt ttttaaatac agtctattat aacattttct
    27481 ataaataaaa tctagactaa tgcagacaat tatagacaac aagccttttt cctaactaaa
    27541 acactcataa agtatagaca attttagact actttggata tcttttggtt agtcattttc
    27601 caaaactaat ttatctaatt tttcagttat atagtatatt gaaactagaa tagtacacct
    27661 ctacttctaa aacattttta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt
    27721 gtttcatttt actatataga tcgcattcga aagaattcgt tccaaaattg cttggttcgt
    27781 tcttctcttg gacgactaaa gaattgatgg gcattatttt tttcaacaat tttcccacag
    27841 tccataaaaa taacatgatg ggctacatct ctagcaaaac ctatctcata aagctgatca
    27901 aaaactcaat ctgaggagaa aatccaataa ggctttccat aataaaggac atcctatcaa
    27961 gatttttgaa cacccgatag gctgcctttt cccgattttg aagacttttt gtccagcttc
    28021 ttttacctta taaataacaa caaaaatcaa agacaagcta gaaagattac cgcagataac
    28081 tcaaacagtg ttttgaggtt gcagataaga ctgacggagt cagctcaaag cactgctttg
    28141 aggttgtaga tagaacaaca tatgcctaag acaaagcgat gctaacctga tttgaagaga
    28201 ttttcgaaaa agattaaata tactctacaa tttgctcaat caattcttgg tcgtctaaac
    28261 ctgtaacttg tataacaaca tctttgactg attgtttagc caacaattca cctaatcgaa
    28321 tactttcttc atcatttaca tcgcgatagt caaaggcata gccaactgtt ttaagtaggt
    28381 ttttatatga caaactgagt tctttcaatt cacgtatcgg ccggatgaat cgttcattat
    28441 agcctaattt tcggattgga gtacgagcta cgcgactaac ctcgtccact atgaaaggat
    28501 tttcaaaccg ttctataatg actttgtgat aattctccaa ttctttttta tcaaagttcc
    28561 atttggcaat caagagactc cgaatttcag ctaatacaga ttcaatccga gatttgatat
    28621 taggattttg aagagcttcc aaaattgtct tggcaccata atgcgcacca atgtaagctg
    28681 aagttgcatg tccagaattg actgaaaaaa gttttcgctc aataaagggt tctaaatctt
    28741 cttcataatg cacatctttt agacgtaaat ctggattttt aagacgcttg gtttccacga
    28801 cccattcatt aaagggctcg accacaacaa aaagggaatc ttcgtgactt tgtgctggaa
    28861 caatcctgtc tactgcagca tttggaaaac ctatgtagtt atcagcaaat gtcaaacctt
    28921 ccggacttaa atatttcttg acttcttgat aaagaaattg agacccgcca atcatatttt
    28981 cacaggccat aacatccaat acctgtgtat tccctgcaac tcggcgagct tcgattcctt
    29041 tggctagaag ttcagcgata aaagggagta tattaggtcc gattgcagta gtaataatat
    29101 ccgtcttttg aatcgcttca atgacttgct caggatgttc tttgctatta atgccagcca
    29161 cattagttac ttctatacga gactgtcctt tctgtgcaat ttcaatttca tacttgccct
    29221 tttcatttag agcatgaatt atctgattat tgacatccac aaaatcaata tggaaaccat
    29281 ttttaaatag aatttcacct ataaaaccac gaccgatatt accggcacca aaatgaacag
    29341 aatgtttcat tcaatttctc cttttcctat ttgagggaca tatatactag atgacaaatg
    29401 acgaaattca attattcaac agcatcaaat aagcgcaata cttcctcttt tgactgagca
    29461 tctgctagtt taagaacatt atccacatct gcacagaaga tagaaatttt ctgaataatt
    29521 tctaagtgtt cattaccaat accagcaata ccaaaaagaa ccgttgccac ttgagggtta
    29581 gatacattcc caaaatcaac ccctctaggg acttgaacga ctgtaatacc agacttgagg
    29641 acatcatttt ttgctgcatc tgttccatgc ggtatggcga taaagttacc catgtaaaca
    29701 gatagctctt tatctcgctc aatcatggct tcaatatagt cttcattaac atatccaccc
    29761 tcataaagaa cttgcccaca ataacaaata gcttcctcct tgttagaaaa ttgtttatta
    29821 agcttaatca aatgtttttc aagtttcata ttagttctcc aatttcttaa ttttttcgtt
    29881 aaaaatagta tttagcatct gataaataat ggattgattt cccgtcttgt aaatctctgt
    29941 ataaagatga ttttcaataa tcgactgact aatagctgtc attaaatctc tagcttcctc
    30001 gctagcttct ttagacatta gcattagcag acaccttttg acctcttctt cctctcgttt
    30061 cattgacaat gcggagatag gtagtttgag ttcaaacata gtaaaactat ttgttgttac
    30121 tttgctagac tgactatgta aaagcaccag accagtatta ggaatagcca taggactatt
    30181 ctggaagtga gataacaatt ttcttgttag gtaatctctg tcactcacat tcttctgata
    30241 ttggatgatt tgttctaccg tgtgctcaaa tgattgatta ttctccaatt gaaccaactc
    30301 gaattgactc aaaagctgac tactagatat taaataatct tgcaagtcat aacttttctc
    30361 tggagcgata gcatcacgcg cgacaattgt acgatgtgcc tgtacatact gaagtcgttc
    30421 ctgtaattca agcaattctt tgacggttgg aaaactagaa attacaccga tttcctgatt
    30481 agtcagcggc ttggtagata aaatataatc atactgactg agatcaatac tgtggtaatc
    30541 tactagagac tgaatatcta tcaactctac aaaaggagca acactcttaa ttttactgac
    30601 taataaatct ctagtgaccc gacgttcatc cgttaaaagc aaaacacgga ctggataaat
    30661 ctctggacta cggcctaagc tagagataaa atgtagggca atcatgccat actcatactc
    30721 tgtatgaaga tatttcggaa aaatatcatt cactaaaaga ctgatgactg tataaagaaa
    30781 tttattcctt tcaactaaaa tctggacaga ttctggcaaa ttttcaccct gaaaaaggat
    30841 agggacgcct aaactgagcc gaatatgatg gaaaagaaaa ttgaataaaa ccttgtcctt
    30901 aaaaaagtca atcttggtat acatggaaac cgtatcaatc agatttgaaa tattgtagaa
    30961 aaattcacca tcaaatttct ccgtaaagag cggattgtcc tgacgtttaa tgattaattc
    31021 atccaagatg ctcgcaaaat agataatttc ctgaatacta taaaattgtg cagtctgctt
    31081 agagtaagtt tgaaaaattt tttgagaaat ttccaaagcc tgcttactag tattaggtga
    31141 attttcaatg ttttgctcct gacctataag agataacaag atcgcaaaaa acatcttcat
    31201 cctagcatcc atatctggaa aacctgacag ttgcttatta acaatctgac tggccagcct
    31261 agttctatct gcttctaaaa tatcaaagct cccaaaatta ccggttgaaa aatctgctac
    31321 tgagatacag tttgtcagta aaatagccaa aaatcttctc ttaccaactg aatcaccaga
    31381 aatccgataa cctttttgtc gttcaatttt cagatcaaag tctaaaagac gcttatcaat
    31441 atctgaaata tcctgaataa tagttacatt actgactttc gtgcactctt gcaatgcttc
    31501 attggtgaca aaaccgctct cagtcagaag gcgataggta atcaactctt gtctttcttg
    31561 gggactatac tcaactaaca cttcaagttc tgtcggcaaa tcatccaact ctccagtcaa
    31621 aatatagtat ttcccatgct tcgttatttc gattccatat tgctccatgc tatctgtcaa
    31681 atctgataaa gttcgataaa ttgttctaga tgaaacctgt aagatttcag tcatatcttg
    31741 cattgaaagc ttccctacat gtaggaaagc cttcaataat tgttcttctc gtttggttaa
    31801 tagcattcgt aatttagaaa cctctagttc tatttgtaca ttctagcagc cattttgtca
    31861 tattctggtg ttgttactaa actatccaca ataagaaatt gagaattcgg tgctgcttgc
    31921 tgcacttctg cctgtaaaga aatagttgtt acaatcatta tgtttttaga attaaattca
    31981 cctaattctg aaattttggc agtagaaact ggaatacgaa tattcttgtt tctaaagata
    32041 gcccgaatcg tttcacagcc catagttgca gttccctgtg ctttaccata agcaactact
    32101 acagcatcaa tatggttaag gtcaatttcc tgactatcta ctggtgctga agttggtata
    32161 tctccttcaa tttctgctat tggaaaagct cctgttaatg aagctacaat ttcatcataa
    32221 cgaggggacg ctaagaaatt atcaacagaa acatgaatag cacttggact cttgtcttta
    32281 gctcttggtg tcagttcttc ctgagtaaca attaatgttt ttggtgtatc aagcaaattt
    32341 gagattgctt gattagatac tggaatctct agacctgctt ttttaacctt atctcgaaga
    32401 atactagctc ccatagcaga gcttcccata ccagcatcgc aggcgaaaat gattttttcc
    32461 actgagtctg tcgaaacaac tgcatcaaca gaagttgata ctaactgacc tttagctgct
    32521 tgggtagccg cctgagcagc ttcgagcgaa tcctcagttg acttgtctgc atgaagaata
    32581 agggctgcta caaggaaaga aacaactgct gccactaaaa cacctaaaag aacatttaga
    32641 tgaggccaaa caccttttgg cgccgtagcc ataatcgcaa taatagaacc tggtgaagct
    32701 ggagatttaa gaccagcgtc taagagttga aaagtaaaag ttccagagat acctcctgcc
    32761 atagcagcta aaaatagagt aggcttcatc ataacataag gaaagtaaat ttcatgaatc
    32821 cctccgaaga aatgaataac cattgccccc caagaagaag atttagcaga acctttaccg
    32881 aatacagcat aagctaatag aattcccagg cctggtccag gattagcttc caataggaag
    32941 agaattgact taccagcttg agctacctgt tctactccca gaggagtaaa aatgccatga
    33001 ttgagggcat tattgaggaa aaggacttta gccggttcga tgataatatt agccatagga
    33061 aggaggcgag cattgacaat agcctcaaca ccattcccaa cagctccagt aagagtcgat
    33121 acgactggac cgattgcgta gaaagccaaa agcaataatg caaaaccaac gagaccagct
    33181 gagaagttat taactaacat ttcaaatccg ggacgaattt tttcttggaa cttctcatca
    33241 aatttcttga tagtccatcc tcccagtggg cccattacca tagctccgat aaacatagga
    33301 acactagaac ctgtgattgc accaacagta gcaatagctc ctacaacggc accacgttgg
    33361 ccatggatca tatatccacc tgtgtaacca atcaggattg gcaataaata cgttaacata
    33421 ggaccaacaa cagtagctaa ctgttcattt ggcagatagc catcagcgat aaagagggca
    33481 gtcaatactc cccaagcaat aaatgctcca atattgggca taaccatatt tgaaagcgat
    33541 gtccctagtt tttgaaccct gactttcaat gatacttttt cttccattag atcatcctcc
    33601 ttttcttaaa actagtatat acaaagttaa aaacctttaa aactaaagtt ttgtcacaga
    33661 ttttgtgtca aaacattact tttgacgagg ctgggcaaaa aggcttaaaa attataaaac
    33721 gcatcatatc aggtgtac
//
LOCUS       DAVHSH010000017        31685 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000017 DAVHSH010000000
VERSION     DAVHSH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31685
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.017"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            213..1694
                     /locus_tag="VVR08_000957"
     CDS             213..1694
                     /locus_tag="VVR08_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6074895.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2056..3051
                     /locus_tag="VVR08_000958"
     CDS             2056..3051
                     /locus_tag="VVR08_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6074896.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            3179..4489
                     /locus_tag="VVR08_000959"
     CDS             3179..4489
                     /locus_tag="VVR08_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6074897.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            4585..5487
                     /locus_tag="VVR08_000960"
     CDS             4585..5487
                     /locus_tag="VVR08_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6074898.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            5489..6334
                     /locus_tag="VVR08_000961"
     CDS             5489..6334
                     /locus_tag="VVR08_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6074899.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            6344..7663
                     /locus_tag="VVR08_000962"
     CDS             6344..7663
                     /locus_tag="VVR08_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6074900.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVEWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(7873..7945)
                     /locus_tag="VVR08_000963"
     tRNA            complement(7873..7945)
                     /locus_tag="VVR08_000963"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7910..7912),aa:Lys,seq:ctt)
     gene            complement(8210..9481)
                     /locus_tag="VVR08_000964"
     CDS             complement(8210..9481)
                     /locus_tag="VVR08_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU6074901.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            9751..9990
                     /locus_tag="VVR08_000965"
     CDS             9751..9990
                     /locus_tag="VVR08_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074902.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10155..10334
                     /locus_tag="VVR08_000966"
     CDS             10155..10334
                     /locus_tag="VVR08_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074903.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10471..10650
                     /locus_tag="VVR08_000967"
     CDS             10471..10650
                     /locus_tag="VVR08_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU6074904.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10687..11139
                     /locus_tag="VVR08_000968"
     CDS             10687..11139
                     /locus_tag="VVR08_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU6074905.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11430..11900
                     /locus_tag="VVR08_000969"
     CDS             11430..11900
                     /locus_tag="VVR08_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU6074906.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     AIFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            11919..13007
                     /locus_tag="VVR08_000970"
                     /pseudo
     CDS             11919..13007
                     /locus_tag="VVR08_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
     gene            12988..13416
                     /locus_tag="VVR08_000971"
     CDS             12988..13416
                     /locus_tag="VVR08_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6074907.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13551..14504
                     /locus_tag="VVR08_000972"
     CDS             13551..14504
                     /locus_tag="VVR08_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU6074908.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNT
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            14506..15249
                     /locus_tag="VVR08_000973"
     CDS             14506..15249
                     /locus_tag="VVR08_000973"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU6074909.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVSGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15260..17056
                     /gene="pepF"
                     /locus_tag="VVR08_000974"
     CDS             15260..17056
                     /gene="pepF"
                     /locus_tag="VVR08_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6074910.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEATFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            17302..18093
                     /locus_tag="VVR08_000975"
     CDS             17302..18093
                     /locus_tag="VVR08_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU6074911.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADVGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQELNAGFRNDLSNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPINRVHEVFNILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            18239..18871
                     /locus_tag="VVR08_000976"
     CDS             18239..18871
                     /locus_tag="VVR08_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU6074912.1"
                     /translation="MLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAIVVAAYSIGTVSG
                     AHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSNSGMSTASLGENA
                     LANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLSLMAMILVGLKIT
                     GLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFLGTEE"
     gene            complement(18896..19243)
                     /locus_tag="VVR08_000977"
     CDS             complement(18896..19243)
                     /locus_tag="VVR08_000977"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074913.1"
                     /translation="MFEVVDKTDEVSSKHCFEVADRTDEVSSKHCFEVADRTDEVSSK
                     HCFEVADRTDEVSSKHCFEVADRTDEVSSKHCFEVADRTDEVSNHTYGKVKLTWFEDI
                     FEEYHTKKPCSSR"
     gene            complement(19305..19838)
                     /gene="queF"
                     /locus_tag="VVR08_000978"
     CDS             complement(19305..19838)
                     /gene="queF"
                     /locus_tag="VVR08_000978"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU6074914.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(20143..20457)
                     /gene="trxA"
                     /locus_tag="VVR08_000979"
     CDS             complement(20143..20457)
                     /gene="trxA"
                     /locus_tag="VVR08_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6074915.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20474..20695)
                     /locus_tag="VVR08_000980"
     CDS             complement(20474..20695)
                     /locus_tag="VVR08_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6074916.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20794..21174)
                     /locus_tag="VVR08_000981"
     CDS             complement(20794..21174)
                     /locus_tag="VVR08_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6074917.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(21319..22272)
                     /locus_tag="VVR08_000982"
     CDS             complement(21319..22272)
                     /locus_tag="VVR08_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6074918.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RRTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22340..23548)
                     /gene="sstT"
                     /locus_tag="VVR08_000983"
                     /pseudo
     CDS             complement(22340..23548)
                     /gene="sstT"
                     /locus_tag="VVR08_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23687..24247
                     /locus_tag="VVR08_000984"
     CDS             23687..24247
                     /locus_tag="VVR08_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU6074919.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            24304..25212
                     /locus_tag="VVR08_000985"
     CDS             24304..25212
                     /locus_tag="VVR08_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6074920.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            25164..25754
                     /locus_tag="VVR08_000986"
     CDS             25164..25754
                     /locus_tag="VVR08_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU6074921.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25757..26863
                     /gene="yqeH"
                     /locus_tag="VVR08_000987"
     CDS             25757..26863
                     /gene="yqeH"
                     /locus_tag="VVR08_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU6074922.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            27077..27388
                     /gene="yhbY"
                     /locus_tag="VVR08_000988"
     CDS             27077..27388
                     /gene="yhbY"
                     /locus_tag="VVR08_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU6074923.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27440..28069
                     /locus_tag="VVR08_000989"
     CDS             27440..28069
                     /locus_tag="VVR08_000989"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU6074924.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            28069..28662
                     /gene="yqeK"
                     /locus_tag="VVR08_000990"
     CDS             28069..28662
                     /gene="yqeK"
                     /locus_tag="VVR08_000990"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU6074925.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            28663..29163
                     /locus_tag="VVR08_000991"
     CDS             28663..29163
                     /locus_tag="VVR08_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6074926.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            29176..29529
                     /gene="rsfS"
                     /locus_tag="VVR08_000992"
     CDS             29176..29529
                     /gene="rsfS"
                     /locus_tag="VVR08_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU6074927.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29632..30378
                     /locus_tag="VVR08_000993"
     CDS             29632..30378
                     /locus_tag="VVR08_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6074928.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30388..31485
                     /locus_tag="VVR08_000994"
     CDS             30388..31485
                     /locus_tag="VVR08_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU6074929.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARESDLPEGIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
BASE COUNT         9623 a         5662 c         6998 g         9402 t
ORIGIN      
        1 attaaaaata taatctttag acttgaattt gattctgtat tcacgccctc aatagacggt
       61 aaaataagaa aattgtttat atattgtctc cgtagtgtta ttatacgaaa taaaagattt
      121 taggaaaagt cgttatatca tgctatacct attctttgtg gtataattgc aagaggttta
      181 atccgataat ttataaagag agaaagatat tcatgagaga tttattatct aaaaaaagtc
      241 ataggcaatt agaattatta gaattattat ttgaacataa acgttggttt catcgttctg
      301 aactagcaga gttattaaat tgtacagaac gtgcagtcaa agatgatcta tcccatgtta
      361 aatctgcttt tcctgacttg atttttcatt cttctactaa tggtatacgc attattaata
      421 ccgatgatag tgatattgaa atggtttacc atcatttctt taaacattca actcattttt
      481 cgattttaga attcatcttc tttaatgaag gttgtcaagc tgagagtatt tgtaaagaat
      541 tttatatcag ttcatcttcg ctctatcgta ttattagcca aatcaataaa gtgattaaaa
      601 ggcaatttca atttgaagtc agtctgaccc ctgttcaaat cattggaaat gagagagaca
      661 ttcgttactt ttttgcacaa tatttttcag aaaaatatta tttcctagaa tggccatttg
      721 aaaatttttc atcagagcca ctatctcaat tgttagaatt ggtttataag gaaacaagct
      781 ttccaatgaa tttgtcaacg catagaatgc taaagttgct cctagttacg aacctatata
      841 gaataaagtt tggtcatttt atggaagtag ataaagattc ttttaacgac caaagtttgg
      901 attttttaat gcaggcagaa ggaatagaag gtgttgctca gagttttgaa tcagaataca
      961 atatctcttt agatgaagaa gttgtttgcc aattatttgt gtcttacttt caaaaaatgt
     1021 ttttcataga tgaaagtctc tttatgaaat gcgtaaaaaa ggatagttat gttgaaaaat
     1081 cttaccatct attgagtgat tttattgatc agatttcagt caagtatcag attgaaatgg
     1141 agaataagga taatctgatt tggcatctgc ataataccgc acatctgtat cgtcaagagt
     1201 tgtttactga gtttatttta tttgatcaaa aagggaatac aatcaggaac tttcaaaata
     1261 tttttccaaa atttgtttca gatataaaaa aagagctttc tcactattta gagactcttg
     1321 aggtttgttc tagttcaatg atggtaaatc atctatctta taccttcatc actcatacca
     1381 aacatttggt gattaatttg ctacaaaatc agcctaaact aaaggtttta gttatgagta
     1441 attttgatca gtatcatgca aaattcgttg cagagacact ttcttattac tgtagcaata
     1501 attttgaact ggaagtttgg actgaattag aattatcaaa ggaatcttta gaagattcac
     1561 cttatgatat cattatttct aattttatta ttcctcctat tgaaaataag agactcatct
     1621 attcaaataa tataaacacg gtctcactca tatacttgtt aaatgccatg atgtttattc
     1681 gattagatga gtaaccaaaa ataacaaaaa aacgctattt cgcgtttgaa ctgtacctca
     1741 aaagttagac agaaaaaatc taatttttgg ggtgtttttg ttaagaaaag accttcaatc
     1801 atttaagcaa aatgtacatc tagatttata gccctctaaa actcttgctt tttttgtaga
     1861 agatacgaaa aaagccataa aaccaaggct tttcctgttt tatgtagatg tttacacatg
     1921 aaaattgaag tattttcaaa agctaattgg agtgatttta ttcatgatgg gataaatgat
     1981 ctggccaaaa atgattgaga aatagttgct taaaaagcat ttgcatgata ctatatattg
     2041 aaaggaggtg ataatatggt agaacaaaga aaatcaatta ccatgaaaga tgttgcttta
     2101 gaagcaggag ttagtgttgg aactgtttca cgtgtaatta ataaagaaaa aggcattaaa
     2161 gaagtaactt taaggaaagt tcaaagggct ataaaaacat tggactatat ccctgataat
     2221 tatgctcgag gtatgaaaaa gaatagaaca gaaactatcg ctttgattat tccgagcata
     2281 tggcatccat ttttttcgga gtttgcctat catgttgaga aagagttatt aaaatataat
     2341 tataaattat ttatttgtaa cgctgatagc gattcacaaa atgaaatcga atatatcgaa
     2401 atgttgaaac aaaataaagt ggatggaatt attggtatta catattctga tattgacaaa
     2461 tatattttat ctgatttacc gtttgtaagt atagatagac atttttcgga aaatgtatgc
     2521 tatgttactt cagcaaatta caaaggagga caaactgcag cagaggaact ggttagaagg
     2581 gataataagc accttgcttt tattggttca attaatatgt atgagaatga gactatactc
     2641 agaagtaaag gattcagaga aaaagctaag gaattaggag tagatgtcta taattttgaa
     2701 atgaaagaac ctttaataaa tcctgaagat cagataagaa tttttttgca atctcataaa
     2761 gaaattgatg gtatatttac aataaatgat atgatggctc tgagagttat tagtgttatg
     2821 aaagaactgg ggaaaatagc acctgatgat taccagataa ttgggtttga tggtttaaaa
     2881 acttctgtcg atcaatctta tctagtgtct acaatagttc aagatattgg tatgatggca
     2941 aaagaatctg ttgcaatgat actgaaaatg attaagcgag aagagattct agaaaaacga
     3001 atcgtaattc ccacatattt ttggggagat aaaacaacaa aaaaaattta aaaagcgctt
     3061 gacaattaat gaaagcgctg ttataatata atcaacaaat gaaacgtttc aaaaataggc
     3121 tagaagcttg tttaaaaaat aaataaaaaa tgaaacgttt caaaaaagga ggaaaatgat
     3181 gcgtaaaggt acaatgttat ctgttgttgc ggggctatcg ttagctatac ttgcaggttg
     3241 tagtggagga actaactcaa aacaagcgag ttcttcaaat gatattaaag tctgggtaca
     3301 attctctgac gaaacaaatg aaggaaaagc ttggcaaaaa gttgttgata actttaatca
     3361 atcaggaaaa agtaagtaca aggttgtaac tgagtatatt cctcgtagtg gtagtggtgg
     3421 aggatatgaa gacaaggtta atgctgctat tacgactaat agtcttccag atgttattac
     3481 ccttgatgga ccaaatacgg cagcttatgc aaaatctaaa gtaattactc cgctagatga
     3541 ttatctaaaa gataataata tggatgatgt tttggacagt attaaacaac agggaactta
     3601 taatgggaaa ttctatgcat ttggattttc tgaatcgaat gttggtgttt attacaataa
     3661 aaaaatgttc aaagaggccg gaattgcgga atcagagctt ccaacgctag aaaagccatg
     3721 gacatgggac gaatttaata cgattgctaa aaaattgaaa gatcattata acaaaccagc
     3781 aattgatttt cgtattaatt caaacgatga aatgttgcca tatgcttata tgccgttgat
     3841 ttggtcaaat aatggttctg tcgtaaacga agatggaaca aaggcagaag gatacttcaa
     3901 ctccaaagag agtgtagaag cagttcaatt cattcaaaat cttgtaaaag aaggctatac
     3961 aactgttagt ccagtcgaaa aaggttttga aacaggagag tatccaatgc ttttgagtgg
     4021 ttcttggacg attgctgaca tgaatacaaa ctacaaagat attgattttg gtatccttcc
     4081 ttacccagta tctagtaaga cgaaaaaatt agtatcccct tcaggtagtt ggcaattagc
     4141 tgtgacgaca aaatctgata aaaaagaggc cgcatctgaa tttgttaaat ttgctacaaa
     4201 tacagaatca agtgaaatta ttagcttggg gaattcggtc cttccaattc gtaaatctac
     4261 aattgaaaat atcaaagata aagtatccga accaatgcgt ttcttgatgg aacaaaattc
     4321 aaaaacagct catgctcgcc cagttgttgt agcatatcct caggtttctc gagcttttca
     4381 acaagcaatg caagatatta gctattatga agaaaatcca aatgtgcaaa aagtcttgga
     4441 tactcgtaca aaagaaatgc aaactgctat tgatcagtca ctcaaataat ctgtaaaaaa
     4501 gaaggtggaa ggaaaatgtt tggaactacc ttcccctttc ttgttaatag cctagtttga
     4561 tatatatgat taaaggagat ggatatgagt aaagaaactg ttgtggatac aaaaagacgt
     4621 gaaaaaataa aggataacat attaggttat agttttttag ctccagcttt aattttatta
     4681 ggtatctttt tagtaattcc agttggaatg gtcatttatt acgcttttac agattattat
     4741 ttgttgacac cagatgaaag aaaatttgtt ggacttgaaa attttattcg attaacaaaa
     4801 gatccgattt tcttaaagag cttcttgaat actttgaaat ttgttgtttg gattattcca
     4861 gttcaattgg gagcggcctt aggaatggct ttgattgtca ataaaaagcg aaaaggaaat
     4921 atgtttttta aagtggcttt ttttgctcca gttgtcatgt ccttggtagt tatttctatt
     4981 ctttggcttt atcttttaaa tccaaatagt ggcttattga atgctatttt aaataaggta
     5041 ggtattgctt ctcaaccttt cttgactagt cctaaacaag ctatgtatgc aattgttttt
     5101 gtttctgctt ggcagggtgc aggttatcag atgcttttat ttttaggagg aatgcagaat
     5161 attccacaag atgtctatga agctgctgaa ttagatggat tctcaaaatg ggctcagttt
     5221 cgttatatca cgatgcccct actaaaacca acagccctgt ttgtattgtt aacaacttta
     5281 atttctgctt ttaagctgat tgtacaacca atggttatga cgcaaggtgg gccattaaac
     5341 tcaacaatta ctatggtgta ctatatttat caacaaggtt ttactgatcg tcttgtagga
     5401 tattctagct caatcgcttt agtatttaca acgttaattg gtatgattag cttagtacaa
     5461 cgtcgcgttc tgaaggagga tgactaagat gaaacgattt aaaccaacaa caatcttaga
     5521 atatattctg ttaactttat tggcaggact cttccttttt cctatggttt ggatggtagt
     5581 ttcagctatg aagccagaag cggatgttta taaaaatttg actagttggc aagccttctt
     5641 accaagttta aatcccgctg attggtttaa accttatcag gaagtatttg agcgctttag
     5701 tatttttaca tatctaggga acagcatttt ttatgctgga acgtttgcta ttggttctat
     5761 tattgtcaat gcactggccg gtttcgcttt tgcaaaagtc aatttttcag gtaagaaaat
     5821 tttatttggt ttcttacttg ctttacttat tattccagtg gaaactgtgt taattccaca
     5881 atttaccatt atcaattcct taggtttggt caataatcgt cttgcagtta ttattccagg
     5941 attggcgagt gtatttaata tttacttatt taggaatttc tttattgcaa ttccagaaga
     6001 gattcttgag tctgcaaaga tggacggagc aagtatcgtt agaattttct ttagaattat
     6061 gcttccaatg tctaaacctg cagttgctac agttggtgtt ttatcattta tttcaagctg
     6121 gaatgattat atctggccat tgatggtttt gacagattct tctaaatttt caatgcaggt
     6181 tgcaattaca actattaata caactcaacc agtttatatc aatcaggtaa tggctgtatt
     6241 aactatttca acgattccgt tgattttggt ctatgtagtc gctcagaaat atattgttca
     6301 aggtctgggt ggttccggaa ctggaataaa ataggatata cttatgataa ataaaacatt
     6361 tacagtagaa aaagccaatc gttttatagc agaaaataaa catctcgtta atactcaata
     6421 taagcctgaa gaacattttt cagctgagat tggttggatc aatgatccaa atggatttgt
     6481 ctattttcgt ggagaatacc atctctttta tcaattctat ccatatgata gtgtttgggg
     6541 gcctatgcac tggggacatg ctaaaagtaa ggacttggtg acttgggagc acttgccagt
     6601 ggcacttgct cctgaccaag attatgaccg aaatggttgt ttctcaggct ctgccattgt
     6661 caaggatgat cgcctctggc tcatgtacac tggacatatc gaagaagaaa ccggtgtccg
     6721 ccaagtgcaa aatatggcat tttcagatga cgggattcac tttgaaaaga tttcccaaaa
     6781 tccagttgca actggagcag acttgccaga tgagttgatt gctgctgatt tccgtgatcc
     6841 aaaactcttt gaaaaagatg gacgctatta ctccgtagta gctaccaaac acaaggataa
     6901 tgtgggctgt atcgttctac tagggtccga taacctagta gaatggcagt tcgaatccat
     6961 ctttttaaaa ggggtagaac accaaggctt tatgtgggaa tgcccagatt acttcgagtt
     7021 agatgggaaa gattgcctta ttatgtcacc catgcgttat cagcgtgagg gagactcata
     7081 tcataacatc aactcatcgc ttttgttcac gggtaaggta gagtggggag aaaaatgttt
     7141 tatcccagaa tcagttcaag aaattgatca tggccaagac ttctatgcgc ctcaaacatt
     7201 gttggacgat caaaatcgtc gtatcctgat tgcttggatg cagacatggg ggcgtaccct
     7261 tccaacccat gaccaagaac acaaatgggc atgtgccatg actttaccta gaattctaag
     7321 attggaagat ggcaaactaa gacaattccc tgttaaaaaa ggccaatatc aaatccaaat
     7381 agataaagat tgtcattacc acttaggaaa tgatatagat tatcttgaat ttggttatga
     7441 cagtaatgcg cagcaagttt acattgatcg tagccatctt attcaaaaaa ttctaggtga
     7501 agaagaacag gacactagtc gacggtatgt agatattgaa gctaaagaat tggaagttgt
     7561 tctagataaa aattccatcg agatttttgt caatcaaggt gaagcaagct tgactgcaac
     7621 ttattactta acggtgccag ctgagctatc acgaattgat taaaaattaa gttatttctc
     7681 ctaaagaaaa agttctcttt ctaaaatagt ggaaagagga ctttttgtgt tttgggtata
     7741 taagcttagt ttatggtatt tgtaaaattg gtgttggatt atgatttaag ctagttttct
     7801 aaagaatttg aaaaaaattt tatttaagca aaaaaaaacc ttggttccaa gacttttcct
     7861 gttgtattta gatgccccct acagggatcg aacctgtgac ccacggatta agagtccgct
     7921 gctctgccag ctgagctaag gaggcaaaga aaaaagctgt attggtgccg aaacttcacg
     7981 gtttgtattg aacccgcgca attaagcagg tgggcaactc gctctaactg aagctgtttc
     8041 cgtgtgagac ggcctacatg ctgttagaag acttttgttt ccctaataat acaaaaaata
     8101 gtcggtcaac acttaagtgt gaagtcgtac accacagcgt ttctatattt atatgatacc
     8161 acttttttaa aaaaaatcaa gaggaaagtg caattttttg aaaaggattt cagatttttc
     8221 gcaaatggtc gatagcttcc tttctttgag ccaaagcccg ttcatattta ccagtatctt
     8281 ctgcttggaa atagtgatga ttacgaattt tttctggcag atagtcttgc tttacccaat
     8341 ttccaggata gttgtgtgga tagagatagt cttgggcatt ccccagttcc ttgcttccac
     8401 tgtagtgccc atcacgtagg tgtcgcggaa taggcaagtg ccctgatgtt ttgaggtcag
     8461 caagtgcctt atccatagct acataggctg agttggattt tggagaaagg gccaaatcaa
     8521 tcacgacatt ggcaatgaga atgcgggctt cggggaaacc aatcctttgt gcagcatcca
     8581 gagcagtcac ggtatgaatc tgggcctcag gattggctaa gccgatatct tcataggcga
     8641 taacagtcaa gcgacgagcg agactaggca gatccccagc ctcaatcaag cgggcagtat
     8701 agtggagact ggcatccaca tctgagccac gaatagactt ttgcagggca gatagaacat
     8761 catagtgacc gtctccatcc ttgtccatag tgatgtagct tctctgaaga ctattttcca
     8821 tgatgtctaa ggtgatgtgg cgaatgccct cgtcattctc aggggtagat agaacagcca
     8881 agtccagtga gttaaaggca gagcgaaggt ctccgtttgt agaggttgcg atgaaatcca
     8941 gcgcatcctc atctagttct attggaaaat caaaaccacg ttcagggtta cttagagcta
     9001 tctgcagggc ctctttgacg tcttggttag acagaggttc caactcgaaa atttgaacac
     9061 ggctacgaat ggcaggagtg acagagaaga aaggattttc agtcgttgct ccaatcatga
     9121 tgaccagtcc actttccaag agaggcaaga ggaagtcttg cttggtctta tctagtcgat
     9181 gaatttcgtc tagcaatagg acgagaccac cagaaaattt agcttcttcc gagatttctt
     9241 gcagtcgctt tttactatca actgtcgcat tgaaagttcg aaaggcatac ttggtcgttc
     9301 cagcgatggc agaggcaata ctggttttgc cgattcccgg agggccatat agaatcatgg
     9361 aggacaggcg gttggcttcc accatgcggc ggatgatttt tccaggtccg accagatgct
     9421 cctgaccgat gacctggtcg atggttttag ggcgcatgcg aagcgcgaga ttgtctggca
     9481 tagcagtcct ttctaacgtg gatttgagta gaatgactca tctactatat cttactatgt
     9541 ccattctagc ctattagttg tgatatttca atggttttgt aataatcagg gagtgagata
     9601 gaatcttttt tactatttaa tttaatgagg agaggtatca gcatgagaga tttgattttc
     9661 cttaaagctc aaaataggat agttgagcct aaagaagtgg aagtgctgac ttgagaaata
     9721 atattgctaa atgtcattgt atgaactata atgaaaagag aggtgataag caatggaaat
     9781 gatggaccaa gtcaggaaat tttgattttt acaaaacaaa ttcgtcattg gattcttagt
     9841 gatcaagtta tttcagggaa aagaaaactt ttcttccggg aagatactcc aaaagagatt
     9901 ttagatttgt acgaaaacat taaatctaaa cttgattttg cttaccaaga agttcattct
     9961 aataatgggt tgaaaaaata tgaaaaatag aataattgat gtttttgaag tagtaaatcg
    10021 catccttgta ataactgttg aaaatcctga tttcgaagac ttgagagtta atcatactca
    10081 atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt acggtaaggc
    10141 gacgttgacg tggtttgaat ttgattttcg aagagtatca gtttgtaaaa attggagata
    10201 aaaaatatag agtacgcagt gttcctatga ttcattcaac tccgcctcaa tctgtcttag
    10261 atcgagatac ttttacaatt gactatacag atgatgaatt gctcgataaa gaagcagttt
    10321 ttactactca ttagaaaaat aggtctgaat aaattggctt cccttagaac cacatctagg
    10381 ggcttttatg tataatagaa taataagtat cactccttta caatacgtgt aacacgtgtt
    10441 ataatggtgt tgtcaggagg taaaagcgct atgcctatga cacaaaaaga gatggttaaa
    10501 ctccttacgg cccatggttg gataaagact agaggcggta aaggctccca tattaaaatg
    10561 gagaagcaag gggaaagact tatcacaatc cctcatggtg agctgaataa gtacactgaa
    10621 agagggataa gaaagcaagc tgggttgtaa aattcagccc ctgttttttg atatggaggt
    10681 agtgaaatgt tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa
    10741 gcgacttatt ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt
    10801 tctgaggctt tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag
    10861 agtgatggag agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat
    10921 ccttttaaag atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct
    10981 atggtatctg ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg
    11041 accataccaa aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact
    11101 ttgacagacg ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt
    11161 aatagtcaat aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat
    11221 ttattagccc tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact
    11281 tttaagaaaa tcactgatat caagggttta aatgaggtaa tatggtataa ttaggacata
    11341 aaataatttt gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg
    11401 attaaagagt cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag
    11461 aggaagagtt ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc
    11521 atgcggtaga agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg
    11581 atgaagacgg agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca
    11641 atcctgccaa gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta
    11701 aaaaaggatt ttctcgcgag tttttagctt attttgccat tttcctcaaa gatactgctg
    11761 aggttgggct agataccctc atggactttt tggaagatcc agaagcagag gaatttgtca
    11821 tggaatggaa ccaagaagtc tttgaagaag gaaaagttgg tttggaagag ggagaatttt
    11881 atccttatcc aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt
    11941 tggtttatgt gctagctttt gtctttatta tgctagcttt tgcttgtgga acaatcgcat
    12001 ttgcagagtt ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc
    12061 taagcatgta tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga
    12121 caggctatcg gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca
    12181 ggtttcatct tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa
    12241 aagaggatga aagcgatcaa agaatcatcc tgatgctttc aggaggcttg atggttcatc
    12301 tcggcttgat attattggcg atagtgtttg gatttttgac aagaagctgg tattttgcag
    12361 ggacttggat ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca
    12421 ccgatggagc aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc
    12481 tggtattgag acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact
    12541 ttgtttaagc agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc
    12601 aaggtgaagt ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat
    12661 tacttgagag gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata
    12721 tcgccttgtt ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca
    12781 aatcgtttct gtctctcaaa ctgtccaatc ttcaagtgat acaagcttgg tatcaattta
    12841 aggtaaagaa agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg
    12901 atagtagtcg aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg
    12961 aaaaggaaat gttagaagga actgaagatg gaactagaaa tttctgattt cccaggctgt
    13021 aagattgctt tgttttgtgg ggataagctc ttgactatct tacgtgatga taaggcaagt
    13081 attccctggg ccaatatgtg ggaactgcca ggtggtggac gtgaaggtga tgaaagtcct
    13141 tttgagtgtg tagcgcgtga agtttatgaa gaactgggca ttcatctgac tgaagattgt
    13201 ctgctttgga gtaaggttta cccaagtatg ctttttgcag acaaacagtc cgtttttcta
    13261 gttggtcagt tgacacagaa ccagtttgac agtatcgtat ttggagatga aggacagggc
    13321 tatcagctga tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa
    13381 gagagattaa aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct
    13441 aaactgaacc cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaaacgtc
    13501 ttcagagaat ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa
    13561 catggcaaga gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct
    13621 tgattgagct gggagcgcaa ggtgttgcga ttgaagacag tctggactat gtgggaaatg
    13681 ttgaccgctt cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag
    13741 cctactaccc tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat
    13801 cagaattgac ggattttatg gatttgggag agttaaaaat aggcacgact gccttggctg
    13861 aggaagactg ggctgacaac tggaagaagt attatgaacc ggcacgcatc acccatgacc
    13921 tgaccatcgt accgtcatgg acggactatg aggcaacagc aggagaaaag attatcaagc
    13981 tggatcctgg tatggccttt gggacaggga cccacccaac aaccaagatg agcctctttg
    14041 ccttggaaca ggttcttcgt ggtggcgaaa cagtgctaga tgtagggact ggttcagggg
    14101 ttctttctat tgcaagctca ctcctaggtg ccaaggagat tttcgcctat gacctggatg
    14161 atgtggcggt tcgtgtcgct caggaaaata ttgagctcaa cactggtatg gaaaatatcc
    14221 atgtagcagc aggagacttg cttaagggag ttgagattga agcagatgtc atcgtggcta
    14281 atatcttggc ggatattctc attcatctga cggaggatgc ttatcgcttg gtaaaggatg
    14341 aaggctacct catcatgagt ggcattatca aggacaagtg ggacatggtg cgcgagtcgg
    14401 ctgagtcagc tggatttttc cttgaaaccc acatggttca aggggaatgg aatgcctgtg
    14461 tctttaagaa aaccaaggat atttctggtg tgattggagg ctaggatgca acagtatttt
    14521 gtcaaaggca gtgctatctc tcctgtcacc atcgaggaca aggaaaccag taagcatatg
    14581 tttcaggtta tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc
    14641 aagcgcttgg cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta
    14701 aatgacaatg tggaactacc agtccaagtg accatcgcat ctggatttcc caagggagac
    14761 aagctggagt tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt
    14821 cctgcagact ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa
    14881 ctagaaaaaa ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt
    14941 aaacttttcg agaaaaaagc agattttcta gctcagctgg accagtttga ctctatcata
    15001 gtagcctatg aagaatcagc taaagaagga gaagccgctg cgctcttaca agcggtctct
    15061 ggtcttgaaa caggagccaa actgctcttt atctttggac cagaaggcgg tctctcacct
    15121 gcagaaatcg aaagttttga agctaaggga gcagttttgg taggcctagg tcctcgtatt
    15181 ttgcgagcag aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta
    15241 gagaaataag aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact
    15301 ctgggactta acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc
    15361 tcgcgaagac atcaaccaat ttagccgtga ctataagggc aatcttcaca cttttgagga
    15421 tttcgagaag gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa
    15481 ctatgctttt atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca
    15541 agctgggatg gaatttgaaa cagatgccag cgtagccttg accttctttg acgatgcctt
    15601 ggtggtagca gacgaggaag tcttggaccg tttgggtgaa ttgcctcact tgacggcagc
    15661 tattcgtcag gccaaaatca aaaaagccca ctatctaggg gctgatgtgg agaaggcctt
    15721 gaccaatctc ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg
    15781 ggattttgaa atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac
    15841 ctatgagaat ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc
    15901 cttctcagag ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt
    15961 caagtctgaa aaactcttgg ctgatatgaa gggatacgac tctgtctttg actatcttct
    16021 agctgaacaa gaagtggacc gtgtcatgtt tgaccgccag attgacctca tcatgaagga
    16081 ctttgcacca gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa
    16141 gatgaccttt gcagactgga aattggactt ggacagcgcc ctgaatcctg aagtgactat
    16201 tgacgatgcc tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca
    16261 ggaagttgct cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga
    16321 ttccggtggt tatgcggcgg acccatatcg cgtacaccct tatgtactca tgagctggac
    16381 aggccgtttg agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat
    16441 cttttcagac aatcatcaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc
    16501 accgtcaacc ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc
    16561 acgtcaaaaa cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat
    16621 cacccacctc ttggaagcca ccttccagcg taaggtgtat acattgattg aagaagggga
    16681 gacctttgga gcaagcaagc tcaacagcat tatgaaggaa gttttgacag atttttgggg
    16741 cgatgccatt gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta
    16801 tatgggcttg tatagttaca cttactcagc aggactagtt atctcgactg ctggttacct
    16861 tcatctaaaa cattctgaaa ctggagctga agactggctc aatctcctta aatcaggtgg
    16921 tagcaagaca ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc
    16981 actccgtgat accatccaat tcttgtctga cacagttgac cagattatct cctatagtgc
    17041 tgagttggga gagtagggga atagaaaaat tttttagaat gatgtttatg ggcttgttaa
    17101 gcgtcattct atttgtctta gttgtagcta ttttcaaaaa tgtcgttgaa ggtcgtgatg
    17161 ttaaatttga acttactgta gaactggtat tgatagttat ttacgtcatt ttatatcaga
    17221 ttgtatttaa ttgagaattc aatattgagt catttaagac tgcctttttg aacagttgct
    17281 agaaatgtag aggtattgac catgtatcaa gatttactaa gaaaaatagc agaagaaaaa
    17341 ccaaattata accaggagga aattcagtgg ttgcttgatc atttgggaga tccttctcca
    17401 gaaattcgtg atgatcttgt ttttacaagc tttgctaagg agattcagga agagctattt
    17461 acacaggaac aatttcattt cattgctgag gtggtcttag ctgatgtagg gttagataaa
    17521 gagattgata aggtaggcct gtcaacactt gaacgttctt ttagggcact tatttatgca
    17581 aatctcttgt ctgcagatgc caaccagcaa tcggtttttt atcaggaatt aaatgcagga
    17641 tttcgtaatg acctttcaaa tcaaggcttg cactatcttt caaaagaaaa ggatacaaca
    17701 ggtttctcaa gtcagtatgg ttgggttcat tcttttgcac atggagccga tttactgaca
    17761 gaggtggttt gtcatccaga ctttcctata aacagagttc atgaagtatt taatatactt
    17821 ggccaactat ttaaaagaat gtcgattcgc tttacagatg atgaggattg gcgtttagca
    17881 agagtgatct acgaacctat tttacaaggg aagttagcgc aagaacaagt agcttcttgg
    17941 ataaaaactg ttgattttcc gatagaagaa agggaggatt tttacaaatt ttccaacttt
    18001 agatcctgtc tggtggaagt ctatgtccaa cttgaccaga gaaatagttt acaagatgag
    18061 ttgaaagaag ctatccagtc ttttcaatac tagagattag ctaatagttc tatgattttc
    18121 aaaaaatttc caatcaattt tcttgaaacc ctttcctact tttgatagac tagtatctag
    18181 tttttgaaaa aaggagaaag aaaatgaaaa atttgttgct gagttaatcg gtacgttcat
    18241 gcttgtgttc gttggaacag gagctgttgt ttttggaaat ggtcttgatg gccttggtca
    18301 ccttggaatc gcctttgcct ttggtttggc aatcgtggtg gcagcctact caatcggaac
    18361 tgtttcaggt gctcacttga acccggctgt ttcgattgct atgtttgtaa acaaacgttt
    18421 gtcatcttca gaacttgtaa actacatcct tggtcaggtt gttggagctt tcatcgcttc
    18481 tggcgcagtc ttcttcctct tgagtaattc aggtatgtca actgctagcc ttggtgaaaa
    18541 tgccttggca aacggtgtca ctgtctttgg tggtttcttg tttgaagtta tcgcaacttt
    18601 cttgtttgtc ttagttatca tgactgtgac ttcagaaagc aagggcaatg gcgcgattgc
    18661 tggtttggta atcggtttgt cattgatggc gatgattctt gtcggattga agattactgg
    18721 actttcagta aacccagctc gtagcttggc accagctgtc ttggtaggcg gcgcagccct
    18781 tcaacaagtt tggattttta tccttgcacc aatcgctggt ggagttcttg cagcccttgt
    18841 tgcaaaaaat ttccttggaa cagaagaata attgaaacta aaaaagcctt gctcctcatc
    18901 ttgaggaaca gggctttttc gtatgatact cttcgaaaat atcttcaaac cacgtcagct
    18961 tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atctgcaacc tcaaaacagt
    19021 gttttgagct gacttcgtca gttctatctg caacctcaaa acagtgtttt gagctgactt
    19081 cgtcagttct atctgcaacc tcaaaacagt gttttgagct aacttcgtca gttctatctg
    19141 caacctcaaa acagtgtttt gagctaactt cgtcagttct atctgcaacc tcaaaacagt
    19201 gttttgagct gacttcgtca gttttatcta caacctcaaa cactgctttg agtaacctgc
    19261 ggctaacttc ctagtttgct ctttgatttt cattgagtat gactttagcg gttgtcaatt
    19321 ttctctggat aaaggtcgtg ttggaagagg cgttgttctg ccaagccctc atacttagtt
    19381 ccttgcttac cgtagttgta gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt
    19441 ccccagactt ctaaatagcg agggtctagc aagttgacca agtctttccc gatggtgttg
    19501 atacagtttt cgtggaaatc tccgtggttt cggtagctaa atagatatag tttgagggat
    19561 tttgactcga cacagagctt gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc
    19621 tgagcagtga tttgtcccag cagagacata tcgaggatat ggtgacgaat gccctgttcc
    19681 ttagcgattt ctctagtaat ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg
    19741 acagcttcga ctgtttcata gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga
    19801 ccaccactaa agacgaccaa ggctgattga tgtttcatag tactccttcc aaaatgggaa
    19861 atgttcagag cacgcaaaaa gctcccatta gggagctaaa aaataccaaa tcgagttttt
    19921 ttagcgatgg catatcccaa acatcgtaat attctactta tatagtaaaa tgaaacaaaa
    19981 acaggacaaa tcgatcagga caatcaaatc gatttctaac aatgttttag aagtagagat
    20041 gtactattct agtttcaatc tactatagtc tagcatattt tttgaaaaat ggcaaagggc
    20101 aagaaaaaag agaccaaaga aagtacttgg tctctcgttt gattagctca attcagcaat
    20161 gatggccttg atttgttctg ctgtgtgaac acctgcaact tgtttgacaa cttggccgtc
    20221 ttttttgaag agaagagttg gaatagacat gattccaaaa gcacgagctg tgtttggatt
    20281 ttcatcaacg tccattttaa cgattttcaa gacatcttct gaaagttctt cagacaattt
    20341 gtccaagatt ggaccttgca tacgacatgg accacaccaa gttgcccaga agtctactaa
    20401 gaccaaaccg tcttttgttt cttgttcgaa tgttgcatct gtaattgctt ttgccattgt
    20461 atttctcctt tttttagtta tattggctta aatcttgttt catgagatag aagaagatat
    20521 ctccataagt cccatggtag tccaaattat gacccttgta agttaatttt tggacagggt
    20581 agtagtctgc gacgccgata aggcaagctt gttgcgaacg ttcaaagtct tcataagact
    20641 cgaaagtcac agttctttcg ttcttgctgg catctatata ggtaatttca atcatgttta
    20701 aaactccttt gtttaatgct aactttattt tactccttat aaaagagaat gtcaagaaaa
    20761 atgattgcgc acgcaacttt ttttaaaatc atcttaaatc aagaaatcca aacctgcttc
    20821 caagctttct tcgacagtct tttgtagcga ggccagtgtc ttttgcccat catttgtcag
    20881 gcagataaaa ctagagcgtc tatcttgatg gcaacacatg cgactgagta gaccgcaatt
    20941 tttagcttcc aagcgagcca ccatcctaga aactgcgctc gggctcagat gaagcttatc
    21001 tggcaggtca atctggcgta gagatttttc ttcagccaag tccagatagt agagcaggta
    21061 gaactctttc aaggtcagac tttgctcgct ctgttgggca atggtctctt ccaagagact
    21121 ttcaatttct ttctgacgcc gattgaagtc aaaccatttt tccaaatagg tcatagtgtc
    21181 tcctttcttt ttagagtcat aattatagaa gaaagtccat taacgggcag tctttgcgtc
    21241 ataagatgat tgcgcatgca ataattatac tacttttcaa gaatgctggc aagctctgtt
    21301 ttttagtggt tttctttttt actgtctata tttttggtaa aaatcaactt ttacttggat
    21361 gaaggttttg gcttcacgta ggagttgaag aagagtggcg cgggtttcaa actcttctct
    21421 tgtcttgggc agactgcggt tccggaagac ttccagataa cgttcaattt catctagcaa
    21481 atcagaagca ggattggtct ggctcagttg acctgcaatt tttgaaaaga gttgcgctaa
    21541 gatcaggctt tcactggcgg caaggtgaca agtgttaatc tgttgggcca tgtttctcag
    21601 gatacgactt tgtcgttgtc tcatctcaaa gtagtggata tggtagtcgg tctggtgaaa
    21661 gaggtggtca gagtgatcca aatagaccag tctgagggct tctttcaaaa gcgtgtctaa
    21721 ttctgctacc agctgtgctc ggttgcgtcc gtctcctctg gataaatagt atttgaagcg
    21781 ctggaggata tcttttaact tttcttccac cagcgtgtgg tagtgctgga tttcctcttc
    21841 tcgtgaaggc atatagagat taacaagcaa ggcaaatcct gtaccaatag caaagagaag
    21901 gaattcgttg actaggaggt ctggagaggt tgactcttga accaagagat ggctaaccaa
    21961 aaccgtgctt ggtgtgatgc caatttccca gcccatcttg taggctaaag gaacgtagaa
    22021 ggccagatag aggccgagac tccagatatg aaatccgctc aagtgaaaag ctagaacgcc
    22081 gatagccaga gctagaagca tagaaaaaag acgattgcga gccagtttta aagtacgtct
    22141 acgcgtatca gataggctca agagagcgat aattccagcc gaaactgctg acgaaagatt
    22201 gagaaaataa gcaagcaggc aggcaagaca ggtagctaag atgagcttgg tcgtacgttg
    22261 gctaatagac ataagaattt cctaataagt tagaataaaa gcgtaaaaga caagacatga
    22321 gcaggcttgc cttgatgagt tattttttac gggttgctgc gtattcggca acggcggtaa
    22381 agaggacatc tgtagaagag ttaagggctg tttcacatga gtcttggatg acaccaatca
    22441 caaaaccaac cccaacaatt tgtatggcaa tatcgttaga aataccgaaa aggctacaag
    22501 caactgggat aagaaggagg gaacctccgg caatacctga agcatcacag gctgagatag
    22561 ctgctaccac actgaggaca aaggctgtgg caaagtcaac aggaattcca agagtgttaa
    22621 ctgtaacaag ggtcaaaacg ttaatggtaa tcgctactcc agccatattg atagtagaac
    22681 cgagtgggat agaaacagaa taggtatctg ggttgagtcc aaggtcatgg cagagtttca
    22741 tgttgacagg aatgttagtc gcagaactac gagtgaaaaa ggctgtcaca ccgctgacac
    22801 ggaggcagtt ccaaactaga gggtaaggat tgcgtctcat aaagaagaag gcaatcaaag
    22861 ggttgaccac aggggcaaca aaaagcatag tcgttactaa tagaaccaat aaaataccgt
    22921 agttggcaag gcttccgact cccttgtcag aaatggtttt aaaaacaaga ccaaggattc
    22981 caaatggagc cagattgatg atccattcga caattttaga agtcacgtca gcgatagttt
    23041 ttagcaattc tttactattt ttactggctt ctctcatagc gattccaaaa atgactgccc
    23101 aagataagat tctaatatag ttagcagtaa gcagggcgtt gactgggttg tcaaccagtt
    23161 tgagcaagag gttgctgagg acctgcccaa tcccatctgg tggtgcaatt tcagtattgg
    23221 cactatttag ggtaatttca atagggacga tgaaacttgc tagtacagct acaagagcag
    23281 cggcgaaagt ccctatcata ggatatacaa gaaaacaaca gttttcatat tgctatcttg
    23341 tcccttttga tgttggaaag ggcattggca acgagggcaa agactaggat aggagcaaca
    23401 gcttttagac ctccaacgaa taaatccccg agtagcccaa tccctgagag attaggaagg
    23461 gtcagtccta ggattcccca caaagcatac caatcaagat acgcttgaca aggcttgcct
    23521 tattccaagc atgaatgatt cttttcataa taatctcctt tttgtgtagt gattatgatt
    23581 atagtataaa tgatagacaa aatcaagaat tttctgtcta ttttttgaat atttatggag
    23641 aatgagactg atgaaaatat ggtataatga aataaaggag ttttatatgc aaaaatttat
    23701 tcaggcttat attgaaaagc tagatgtgac aaccattatc gagaatattc taaccaaggt
    23761 catttctctt ttactgcttt tgattgtatt ttatattgct aaaaaaatgc ttcataccat
    23821 ggtgcagaga attgtcaaac cttctctaaa aatgtctcgt catgatgtcg gacgccaaaa
    23881 aaccatctca cgtttactag aaaatgtgtt taattatacg ctatatttct ttttactcta
    23941 ctgcattttg tcgattttag gtttgccagt ttctagtttg ctggctggag ctggtattgc
    24001 tggggtagcg attggtatgg gagcccaagg ctttctgtct gatgtcatca atggcttttt
    24061 catcctcttt gaacgtcaac tggatgtggg agatgaggtc gttctgacaa atggaccgat
    24121 tactgtatcg ggtaaggttg tcagtgtggg aattcgtacg acacagcttc gtagcgagga
    24181 gcaagccctt cactttgtcc ctaaccgaaa tatcacagtt gttagcaatt tctcacgcac
    24241 agactagacc tgttatttta agtaatttgt ggtacaatag agggagttta ataaggagaa
    24301 aagatggttt tagaaaagca gttgggcaat ggttgtacct ggatagacct agacctagga
    24361 aagttgaata aactagaaga cctttctgaa atttacggtt tggacaagga aaccattgaa
    24421 tacgcactgg atagaaacga gcgcgcccac atggattacc accgtgaaag tgggacggtt
    24481 acctttatct ataatgtcct agacgtaaaa aaggacaagg cctactatga gacttttccc
    24541 atgaccttta ttgtcgagca tcgtcgcctg attaccatta gtaataccaa gaacgcctat
    24601 gtcattgaac agatgactcg ttatctggag agccatgaca cgctttcgat ttataagttt
    24661 ctctttgcca gtctggaaat tatcagcaat gcctactatc ctgtcattga gcagatggac
    24721 aagagtaggg atgaggtcaa tgacctcttg cgccagcgaa ctaccaagaa aaacctcttt
    24781 gccctgtctg atttggagac tggtatggtt tatctgacgg cagctgccaa acaaaatcgg
    24841 attttgttag agcatattca aggtcatgcc ttgtatcgta gttttgatga gattgagaga
    24901 gaacagtttg atgatgccat gattgaggct catcagctgg tatccatgac agacctaatc
    24961 tctcagattt tacagcagct ttcagcctct tacaacaata ttctaaacaa taatctgaat
    25021 gacaatttga caaccttgac tatcatttca gtcttgctag ctgttttggc agtcgtgaca
    25081 ggctttttcg gaatgaatgt tcccttacct ttaacagatg agccccatgc ttggctctat
    25141 atcagtttgg ctagtgcagg tttgtggatt gttttatcct tgttactaag gaaaattgcg
    25201 aaaaaaagtt aagaaaagga gccagaatgg cgattgaaaa ttatatacca gattttgctg
    25261 tggaagcagt ctatgatctg acagtcccaa gcctgcaggc gcagggaatc aaggctgttt
    25321 tggtcgattt ggataatacc ctcattgctt ggaacaaccc tgatggaacg ccagagatga
    25381 agcaatggct acatgacctt cgggacgcgg gtattggcat tatcgtagtg tcaaataaca
    25441 ccaaaaaacg cgttcaacga gcagttgaga aatttgggat tgattacgtt tactgggcct
    25501 tgaagccctt cacatttggt attgaccgtg ctatgaagga attccactat gacaaaaagg
    25561 aagtggtcat ggttggcgac cagctcatga cagatatacg agcagcccac cgtgcaggga
    25621 ttcggtcaat tttagtcaaa cccttggtcc aacatgactc aatcaaaacg cagattaacc
    25681 gaactcgtga gcgtcgtgtt atgagaaaaa tcactgaaaa gtacggaccg attacatata
    25741 aaaaaggaat ttaactatgg aagaaattct ctgtattggt tgtggagcaa ccattcagac
    25801 gacagataaa gctggtcttg gttttacccc ccagtcggca cttgaaaaag gtttggagac
    25861 tggcgaagtc tattgccaac gctgtttccg tctccgccac tacaatgaaa tcacagatgt
    25921 ccagttgacg aacgatgatt tcctcaagct cttgcacgag gtgggagaca gtgatgcctt
    25981 agtggtcaat gtcattgata tctttgattt taatggatct gtcatcccag gtttaccacg
    26041 tttcgtctcg ggcaatgatg tcctcttggt aggaaataaa aaagatatcc ttcctaagtc
    26101 agttaagtct ggtaagatta gccagtggct catgaaacgt gcccatgaag aaggtcttcg
    26161 tccagtcgat gtggtcctaa cttcagcaca aaataaacat gccattaagg aagtcattga
    26221 caagattgaa cactaccgta agggccgcga tgtctatgtg gtcggtgtga ccaacgttgg
    26281 aaaatcaact ctaatcaatg ctattatcca agaaatcacg ggtgatcaga atgtcatcac
    26341 tacttcacgc ttcccaggta caaccttgga caaaatagag attccgcttg acgacggatc
    26401 ttatatttac gatacgccgg gaattatcca ccgccaccag atggctcact acttgacggc
    26461 caaaaacctc aagtatgtca gtcctaaaaa ggaaatcaag cctaagacct atcagcttaa
    26521 tcctgagcaa accctatttt taggtggttt gggacgcttt gactttatag caggagaaaa
    26581 gcaaggattt actgctttct ttgataatga actcaaactc catcgtagca agcttgaagg
    26641 agctagtgct ttctacgata agcacctggg aactcttctg acaccaccaa atagcaagga
    26701 aaaagaagat ttcccaaggc tagtccagca tgtctttacc attaaagata agacagacct
    26761 agtcatctca ggcctaggct ggattcgtgt aacaggcata gcaaaagtcg ccgtctgggc
    26821 accagaaggc gtcgccgtcg tcacacgaaa agcaattatt taaaacaaaa tcgctgagcg
    26881 aacaaagtga gctcatatag cgatagttat tgccgtggtg tgattgccaa tctgtagatt
    26941 ggcaaggggc acaattgaga ccaaggctca attgtgaggt caggaaatcc atttttcaaa
    27001 gatgaaatct ttggaaaatt agttccgacc gtccctcacc acctaaaata actatccaaa
    27061 aacaaggaag aaaattatgt cattaacatc aaaacaacgt gccttcctca acagccaggc
    27121 acacaccctc aaacctatca tccaaatcgg gaaaaatgga ctcaacgacc aaatcaaaac
    27181 cagcgtccgt caagctcttg atgcgcgtga attaatcaag gttactctct tacaaaacac
    27241 agatgaaaat atccacgaag tagctgaaat tttggaagaa gaaatcggtg tggatacagt
    27301 ccaaaaaata ggacgcatct tgattttgtt taaacaatct agcaagaaag aaaatcgcaa
    27361 gatttctaag aaagtcaaag aaatctaaga ccgaaactcc aaataactgt ttttatagag
    27421 aaataaaggg gactagccta tgacaatcga actattgact ccctttacca aggtagagtt
    27481 ggagccagaa atcaaggaga aaaaacgcaa acaagttggg attttagggg ggaattttaa
    27541 ccctgttcac aatgcccatc tcattgttgc ggatcaagta cggcaacagt tgggactgga
    27601 tcaagttctt ctcatgcctg aataccaacc tcctcacgtt gataaaaagg aaaccatccc
    27661 tgaacaccat cgtctcaaga tgcttgagtt ggcaattgag gggattgacg gcctagtcat
    27721 tgaaaccatt gagttggagc gcaagggtat ttcctacacc tacgacacca tgaaaatctt
    27781 gacagagcaa catccagata cggattatta ctttatcatc ggtgccgaca tggttgacta
    27841 tctgcctaag tggtaccgaa ttgatgaact ggttgacatg gttcagtttg tgggggttca
    27901 gcgtccacgc tacaaggcag ggacttccta tccagttatc tgggtggacg taccgctcat
    27961 ggatatctcg tccagcatgg tgcgggactt cattgcccaa ggtcggaaac ccaactttct
    28021 cctacctcag ccagtgctag actacatcga gaaggagggg ctctactgat gtcctatcaa
    28081 gactatatca actgctcccg tgaggccttg ttggaaaaaa tggcagagct tctacctgag
    28141 aaacgtctaa cccattgtct aggtgtggag cgtgccgcta tggagttagc tcagcgcttt
    28201 ggtgtagatg ttgggaaagc aagtctagca ggtcttcttc atgactatgc taaaaagttg
    28261 tcagatcagg aatttctaga cttgattgac cgttatcagc tagatttcga cctcaaaaac
    28321 tggggtaata atgtctggca tggtatggtc ggaatttaca aaattcagga agatttggat
    28381 ttgcatgatt cagaaatcct gcgagccatt gaagtccata cagtcggtgc tggtcaaatg
    28441 acagacctag ataaggtcat ctacgtcgca gactatatcg agcacaatcg agcctttcct
    28501 ggagtagatg tggcgcgtga gattgcaagt ctatcgctca ataaggcggt ggcctacgaa
    28561 acagctcgta ccgtggagta tctagctcat cagggattcc ccatctatcc ccaaaccctt
    28621 gaaacctata acgcctttgt gcactatttg aaagaggact aaatgaagac ggcttttata
    28681 atcattgatg ttcagaatgt tttagtagaa actgggttcc agacaaaaag tctattggaa
    28741 aaaatttctt atttacaaaa ccaggctaga agcaagaata ttgaaattat ctatgttcaa
    28801 catattgaga attctgaagc tcaaacatca gaagattggc agttatctgc gcttttaaat
    28861 cgaaaacctg ctgaaaaggt ctttcagaag aagtataaca gtattttcaa agaaactggc
    28921 ttaaaagaat acttggataa acaggggatt gaaaaattag ttttatgtgg tatgcagaca
    28981 gaatattgtg tggatacctc tgtcaaggtt gcctttgaat atggctatca gcttattgtt
    29041 ccagaaggtg ctgtcacaac ctttgatggg gatgacattc cagcagaaac gattaatgaa
    29101 ttttatgagg acatttggga ggagcacttt gcagatgtcc tagattacaa acatattttc
    29161 taaaaagagg attaaatgaa cgaaaaagaa ttactagaac tagtcgtgaa agcggctgat
    29221 gagaaacgtg cggaggatat cctcgcactt gatgtacaag atttgactag tgtgacggac
    29281 tactttgtca tcactagctc aatgaatagc cgtcagttgg acgctatcgc agctaatatc
    29341 cgtgaaaaag tagctcaagc gggctttaaa ggtagccatg tcgaaggcga tgcagctgga
    29401 ggctgggtct tactggacct cggtgctgtt gtcgtgcata tcttttcaga agaaatgcgt
    29461 gcccattata atctagagaa gctatggcat gaggcgaatt cagtagatat ttcagaagct
    29521 cttgcttaga agatgaactc agttgtagtc aactgggttt ctttgcttat tttagaaaaa
    29581 ttgatagaaa ggtaaagggc tagtggtgtt taccatggag ctcttagtat catgattatg
    29641 gcgacttatg aaacctttgc ggcggtctat gatgcggtca tggacgatag tttatacgac
    29701 aaatggacaa atttttctct gcgtcatttg cctaagacca aggagaaaaa gaaactcttg
    29761 gaactggctt gtgggacagg aattcaatca gtgcgcttct ctcaggctgg ttttgatgtg
    29821 actggacttg acttgagtgc ggatatgttg aagattgcgg agaagagagc aacttcagcc
    29881 aagcaaaaga ttgcttttat agaaggtaat atgctaaatt tgtccaaggc agggaaatac
    29941 gattttgtca cgtgttattc ggactctatc tgctatatgc aggatgaggt ggaagtaggg
    30001 gacgtcttta aggacgtgta caatgcgctg aatgaagagg gagttttcat ctttgacgtg
    30061 cactcgacct accagacaga tgaagtattc cctggctatt cctaccatga aaatgcggaa
    30121 gatttttcca tgctttggga tacatatgag gacgaagttc ctcactccat cgtgcatgag
    30181 ctgactttct ttatcaagga ggctgacggt tcctttagtc gccacgatga agtacatgag
    30241 gagaggacct atgagatctt gacctatgat atcttgctgg aacaggctgg attcaagtcc
    30301 ttcaaactct atgcagactt tgaggataag gagccaacag aaactagcac ccgttggttt
    30361 tttgtggcgc agaagtagga gattagcatg accatcacag gtattatcgc ggagttcaat
    30421 ccttttcata atggccataa atacctgctg gatcaggcag agggactgaa aattgttgcc
    30481 atgtcaggga atttcatgca gcgtggagag cccgctattg tggataagtg gacaagggcc
    30541 cagatggcgc tggaaaatgg cgcagacttg gtagtggaat tgcccttttt agtcagtgtt
    30601 caggcagctg atttctttgg tcaaggagct gtggatatct tggatcgctt gggcattgat
    30661 agtctagttt ttgggacaga ggaagttcga gattatcaga aaatcgctga cttatacaca
    30721 gagaaaggtg ctgagatgga gaaatttgtg gaaaatctgc ctgattccct ttcctatccc
    30781 cagaaaaccc aagctatgtg gaaggaattt gctggtcttg atttttcagg taataccccc
    30841 aatcatgttc ttgctctggc ctatgcaaag gcggttgcag gacgaaatat caagctgcat
    30901 ccgattcagc gtcagggggc aggttaccat tctgtgaata aagatgtgga ctttgcctcg
    30961 gcgacagccc tccgtcaaca tcagaaggac caagatttct tagaacgttt tatgccttct
    31021 gttgccctat ttgagcaggc cagtaaggtg atctgggaag actattttcc cttgctccgc
    31081 tatcaaatct tgtcaaatcc cgacctaacc accatctatc aggtcaatca agaaatggct
    31141 gtgcgcatta aagaagctat taaaacagcc cagtctgtgg aagaattggt cgagttagtg
    31201 accaccaaac gttacaccaa ggcgcgtgtc agacgcctct tgacctatat cttggtgcag
    31261 gctagagaaa gtgacttgcc agaagggatt catgtccttg gctttaccga aaaaggcagg
    31321 caacatctta aatatctgaa agggcaggtc agtctagtca gcagaattgg caaggaacct
    31381 tgggatgtca tgactcaaaa ggcagaccag atttaccaat tgggaaatcc aagtatagca
    31441 gaacagaatt ttggcagagt gccgattaga atagaaacaa actaagtcta ctgaaaggta
    31501 ggctttttta ttgtagaaat tttagctaac aaattgaaga taaagttttt ggaaaatgat
    31561 aaactcccta atacagaaga caaaaagtca ataaagaaaa ttagtatatg aaccttaatc
    31621 tttatctttg aatccgcttt atgcttgtta ttttgtggta taatgaagag aactggttat
    31681 attaa
//
LOCUS       DAVHSH010000018        29882 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000018 DAVHSH010000000
VERSION     DAVHSH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.018"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            133..891
                     /locus_tag="VVR08_000995"
     CDS             133..891
                     /locus_tag="VVR08_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6074930.1"
                     /translation="MALVEFKNVEKYYGDYHALRDINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            902..1696
                     /locus_tag="VVR08_000996"
     CDS             902..1696
                     /locus_tag="VVR08_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6074931.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            1709..2386
                     /locus_tag="VVR08_000997"
     CDS             1709..2386
                     /locus_tag="VVR08_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6074932.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            2396..3055
                     /locus_tag="VVR08_000998"
     CDS             2396..3055
                     /locus_tag="VVR08_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6074933.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            3350..4540
                     /locus_tag="VVR08_000999"
     CDS             3350..4540
                     /locus_tag="VVR08_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU6074934.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(4861..5742)
                     /locus_tag="VVR08_001000"
     CDS             complement(4861..5742)
                     /locus_tag="VVR08_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU6074935.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(5883..7211)
                     /gene="vncS"
                     /locus_tag="VVR08_001001"
     CDS             complement(5883..7211)
                     /gene="vncS"
                     /locus_tag="VVR08_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU6074936.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYAWTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     NEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(7208..7864)
                     /gene="vncR"
                     /locus_tag="VVR08_001002"
     CDS             complement(7208..7864)
                     /gene="vncR"
                     /locus_tag="VVR08_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU6074937.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIQKLRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(7913..7996)
                     /gene="pep27"
                     /locus_tag="VVR08_001003"
     CDS             complement(7913..7996)
                     /gene="pep27"
                     /locus_tag="VVR08_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU6074938.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(8176..9555)
                     /gene="vex3"
                     /locus_tag="VVR08_001004"
     CDS             complement(8176..9555)
                     /gene="vex3"
                     /locus_tag="VVR08_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU6074939.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(9607..10254)
                     /gene="vex2"
                     /locus_tag="VVR08_001005"
     CDS             complement(9607..10254)
                     /gene="vex2"
                     /locus_tag="VVR08_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU6074940.1"
                     /translation="MTLLQLQDVTYRYKNIAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(10267..11544)
                     /locus_tag="VVR08_001006"
     CDS             complement(10267..11544)
                     /locus_tag="VVR08_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6074941.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(11900..12070)
                     /locus_tag="VVR08_001007"
                     /pseudo
     CDS             complement(11900..12070)
                     /locus_tag="VVR08_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(12213..12812)
                     /locus_tag="VVR08_001008"
     CDS             complement(12213..12812)
                     /locus_tag="VVR08_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074942.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEEIGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNTK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDTIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(12949..13833)
                     /locus_tag="VVR08_001009"
     CDS             complement(12949..13833)
                     /locus_tag="VVR08_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU6074943.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(13837..14223)
                     /locus_tag="VVR08_001010"
     CDS             complement(13837..14223)
                     /locus_tag="VVR08_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU6074944.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(14216..15559)
                     /locus_tag="VVR08_001011"
     CDS             complement(14216..15559)
                     /locus_tag="VVR08_001011"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU6074945.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIERGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(15641..16525)
                     /locus_tag="VVR08_001012"
     CDS             complement(15641..16525)
                     /locus_tag="VVR08_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074946.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(16537..17154)
                     /gene="cysE"
                     /locus_tag="VVR08_001013"
     CDS             complement(16537..17154)
                     /gene="cysE"
                     /locus_tag="VVR08_001013"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU6074947.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(17170..19383)
                     /gene="pnp"
                     /locus_tag="VVR08_001014"
     CDS             complement(17170..19383)
                     /gene="pnp"
                     /locus_tag="VVR08_001014"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU6074948.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(20068..20934)
                     /gene="metF"
                     /locus_tag="VVR08_001015"
     CDS             complement(20068..20934)
                     /gene="metF"
                     /locus_tag="VVR08_001015"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU6074949.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(20998..23247)
                     /gene="metE"
                     /locus_tag="VVR08_001016"
     CDS             complement(20998..23247)
                     /gene="metE"
                     /locus_tag="VVR08_001016"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU6074950.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(23508..23774)
                     /locus_tag="VVR08_001017"
     CDS             complement(23508..23774)
                     /locus_tag="VVR08_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6074951.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(23899..24302)
                     /locus_tag="VVR08_001018"
                     /pseudo
     CDS             complement(23899..24302)
                     /locus_tag="VVR08_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            24458..25459
                     /locus_tag="VVR08_001019"
     CDS             24458..25459
                     /locus_tag="VVR08_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6074952.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSAPNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            complement(25527..27932)
                     /locus_tag="VVR08_001020"
     CDS             complement(25527..27932)
                     /locus_tag="VVR08_001020"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU6074953.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETDQVAADALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(28009..28506)
                     /locus_tag="VVR08_001021"
     CDS             complement(28009..28506)
                     /locus_tag="VVR08_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6074954.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFAYDNTEEQLQEYFEEAYSLKTLS
                     TELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGFGLGK
                     QLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDTDWLL
                     RKKLR"
     gene            complement(28506..29552)
                     /gene="pheS"
                     /locus_tag="VVR08_001022"
     CDS             complement(28506..29552)
                     /gene="pheS"
                     /locus_tag="VVR08_001022"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU6074955.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVASQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT         8377 a         6752 c         5714 g         9039 t
ORIGIN      
        1 atcgatttga ctgtcccgat cgatttttcc tgttcttatt tcactatagt gaattttttc
       61 agatatgatt tgacaagaac attcttttat tgtagaatca tgtcataaaa tctaacacaa
      121 gggagagctc tcatggcttt agtagaattt aaaaacgtcg aaaaatatta cggagactac
      181 catgcactcc gcgacatcaa tctccgtttt gaaaaaggac aagtcgttgt cctactcgga
      241 ccatctggtt ctgggaaatc cactcttatc cgtaccatca atggtttgga ggctgtcgac
      301 aagggaagcc ttctagtcaa tggccaccaa gttgctggtg ccagccagaa agatttggta
      361 cctcttcgca aggaagtcgg catggttttc cagcatttta acctctaccc tcacaaaaca
      421 gtgttagaaa acgtaacact cgcacccatt aaagttctag gaattgataa aaaagaagct
      481 gaaaaaaccg cccaaaaata tctggaattt gtaaatatgt gggacaagaa agattcctat
      541 cccgccatgc tatctggtgg acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg
      601 catccggaac tcctcctctt tgatgaacca acatctgctc ttgatcctga gactatcgga
      661 gatgttctag cagttatgca gaaactggcg catgatggga tgaacatgat catcgttacc
      721 cacgaaatgg gctttgctcg agaggttgcg gaccgcatta tctttatggc cgacggagaa
      781 gttttagtag atacgacaga tgtcgataac ttttttgaca atccaagcga acctcgtgcc
      841 caacaattcc tcagcaaaat tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc
      901 tatgaaaaaa aaattctttt tatcagcatt attgattagc cttttcggcc ttgctgctgc
      961 caaaccagtc caggctgata ctagtatcgc agacattcaa aaaagaggcg aactggttgt
     1021 cggtgtcaaa caagacgttc ccaattttgg ttacaaagat cccaagaccg gtacttattc
     1081 tggtatcgaa accgacttgg ccaagatggt agctgatgaa ctcaaggtca agattcgcta
     1141 tgtgccggtt acagcacaaa cccgcggccc ccttctagac aatgaacagg tcgatatgga
     1201 tatcgcgacc tttaccatca cggacgaacg caaaaaactc tacaacttta ccagtcccta
     1261 ctacacagac gcttctggat ttttggtcaa taaatctgcc aaaatcaaaa agattgagga
     1321 cctaaacggc aaaaccatcg gagtcgccca aggttctatc acccaacgcc taattactga
     1381 actgggtaaa aagaaaggtc tgaagtttaa attcgtcgaa cttggttcct acccagaatt
     1441 gattacttcc cttcacgctc atcgtatcga tgccttttcc gttgaccgct ctattctgtc
     1501 tggctacact agtaaacgca cagaactact agatgatagt ttcaagccat ctgactacgg
     1561 tattgttacc aagaaatcaa atacagagct caacgactat cttgataact tggttactaa
     1621 atggagcaag gatggtagtt tgcagaaact ttatgaccgt tacaagctca aaccatctag
     1681 ccatactgca gattaaggag gacaccccat gacagattta tcatcttgga cagcctattt
     1741 tcaggatttt ggacaatttt tcaatggttt cctctttact cttgccctag cgattggatc
     1801 ctttatcctc gccatggtct taggaatctt ctttggtgcc atgtcaacca gtaaacgtcc
     1861 aattttacgc attttagctc acatctttgt ggaattttac caaaacactc ccctcttggt
     1921 gcagtttgtt attgtttttt atggcctacc tcttatcagt gaccatacta tcatgattcc
     1981 aatttattgg acagctgttc tctgcgtggg actctatcac ggcgcttata tcgctgaggt
     2041 tattcgttca gggattcagt ctattcctag tggtcagatg gaggccgcct tgtcgcaagg
     2101 ttttacctat atcagtgcca tgcgcttgat tatcttgcct cagaccttcc gcatcattct
     2161 ccctccattg accaaccaaa ttgttaacct catcaagaac acctctactg tagctatcat
     2221 ctctggagta gacttgatgt ttgtgactaa gtcttggtcg gctctcaacg gaaactatat
     2281 cccagccttt ttaggtgctg ctcttctcta ctttgctcta tgcttccctg ttgcccagtt
     2341 tggtcgcaag atggagcaag ccaacaaaaa agcctattca ctttaggagg ttactatgga
     2401 atctatttta gaagttttaa ccccagataa cctagtcttt atctttaaag gatttggctt
     2461 gaccctctat atttctctga ttgccatcat cctctctact atcatcggta cggtgctagc
     2521 tgtcatgaga aatggcaaaa atcctgtctt acgcattatt tccagtattt atatcgagtt
     2581 tgtgcgcaac gttcccaacc ttctctggat ttttactatc tttttggtgt tcaaaatgaa
     2641 atccacacca gcaggtatta cagcctttac tctctttaca tcagcagcct tggctgagat
     2701 tattcgaggc ggtctcaatg ccgtagacaa gggacagtac gaagcaggaa tgtcacaagg
     2761 cttcacctca gcccaaatcc tctactacat cattctccca caagccatcc gcaaaatgct
     2821 accagccatc atttctcagt ttgttaccgt gattaaggat accagtctcc tctactctgt
     2881 tatcgcccta caagaactct ttggagccag ccaaattctc atgggccgtt atttcgaacc
     2941 agagcaggtc ttcagtcttt acatcctgat tgccctcatc tacttcagct ttaacctagc
     3001 aatttctagc ctgtctcata tgctagccaa acgttggcaa caagctgcag aataatactc
     3061 ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg tatatatgtt actgacttcg
     3121 tcagttctat ccacaacctc aaaacggtgt tttgagcagc ctgcggctag cttcctagtt
     3181 tgctctttga ttttcattga gtataaacag ccactctcca gttcaattgg agagtttttt
     3241 gatgagagta gatatttata gacctcaatt tgacaccata cattttctat gataaaatgt
     3301 aacaaattca tttacaacaa atcgaaatct aaatgaaatg gaattttcta tgaaatcagt
     3361 caaaggacta ctctttatca tagctagttt tatcttgact cttttgactt ggatgaacac
     3421 ttctccccaa ttcatgattc caggactagc tttaacaagc ctatctctga cttttatcct
     3481 agccactcgt ctcccactac tagaaagctg gtttcacggt ttggagaagg tctacaccgt
     3541 ccacaaattc acagcctttc tctccatcat cctactaatc tttcataact ttagtatggg
     3601 cggtttgtgg ggctctcgct tagctgctca gtttggtaat cttgccatct atatctttgc
     3661 cagcatcatc cttgtcgcct atttaggcaa atacatccaa tacgaagctt ggcgatggat
     3721 tcaccgtctg gtttacctag cctatatttt aggactcttt cacatctaca tgataatggg
     3781 caatcgtctc cttacattta atcttctaag ttttcttgtt ggtagctatg cccttttagg
     3841 cttactagct ggtttttata tcatttttct atatcaaaag atttccttcc cctatctagg
     3901 aaaaattacc catctcaaac gcttaaatca cgatactaga gaaattcaaa tccatcttag
     3961 cagacctttc aactatcaat caggacaatt tgcctttcta aagattttcc aagaaggctt
     4021 tgaaagtgct ccgcatccct tttctatctc aggaggtcat ggtcaaactc tttactttac
     4081 tgttaaaaat tcaggcgacc ataccaagaa tatctatgat aatcttcaag ccggcagcaa
     4141 agtaacccta gacagagctt acggacacat gatcatagaa gaaggacgag aaaatcaggt
     4201 ttggattgct ggaggtattg ggatcacccc cttcatctct tacatccgtg aacatcctat
     4261 tttagataaa caggttcact tctactatag cttccgtgga gatgaaaatg cagtctacct
     4321 agatttactc cgtaactatg ctcagaaaaa tcctaatttt gaactccatc taatcgacag
     4381 tacgaaagac ggctatctta attttgaaca aaaagaagtg cccgaacatg caaccgtcta
     4441 tatgtgtggt cctatttcta tgatgaaggc acttgccaaa cagattaaga aacaaaatcc
     4501 aaaaacagag cttatttacg aaggattcaa gttcaaataa gtaatcatac tctcctggga
     4561 tttcccagga gagtttttta tagccaaatg aaataagacc ggaacgatgg aattttggca
     4621 ttcaaatcaa ttgataagaa tattttatag tggagtgaaa taggatacga acaaattgat
     4681 taggaaaatc aaatgaattt atagaaatct tttagcagtt atgttgtcct attctagttt
     4741 caaaacgcta tagaagcagc attgtgctag tctagattca gtttactata ctaaaacgag
     4801 tagcttgaaa tcaaaaaacc caccctcaca ggcaggtttt atctgtatta ttcagctaga
     4861 ttatgcttta ccttctgaac cgaatacgtc gatacgttct tcaaccgatg cttggatagc
     4921 ttttacaccg tcagccaaga atttacgtgg gtcgaagagt tttttcttgt cgtattctgc
     4981 ttcgtttgct tcgtagtcac gagcaaattt acgagttgcg ttagcgaatg cgatttggca
     5041 ttctgtgtta acgttaactt tggcaacacc aagtttgata gctgcttgga tttgctcatc
     5101 aggaatacct gatccaccgt gcaatacgat tgggaatcct ggaagagctt ctgtcaattt
     5161 ttgcaagtgg tcaaggtcaa gaccttccca gtttactggg taaggaccgt ggatgttacc
     5221 gataccagct gccaagaagt cgataccagt ttcaaccatt gctttagcgt cttcgattgg
     5281 agccaattca cctttaccga tgattccatc ttcttcacca ccgatagtac caacttcagc
     5341 ttctactgag atacctttag cgtgtgcttt ttcaacaact tctttagcca atttaagatt
     5401 ttcttcaact ggaaggtgtg aaccgtcaaa catgattgaa gtataaccaa cttcgataca
     5461 ctcaagtgca tcttcgtagt gaccgtggtc aaggtggata gctactggta cagtgatacc
     5521 cattgattca acaaggttag cgatcaagtt gcgagcaact ttgtaaccac ccatgtattt
     5581 agcagcaccc attgaagttt ggatcaaaac tggagctttt ttagcttctg ctgcgcgcaa
     5641 gatagcttga gtccactcaa ggttgtttgt gttaaatcca ccaactgcat aaccgttgtc
     5701 acgggctgct tggacaaatt tttctgctga aacgattgcc attttatcag gcctcctgta
     5761 tatttttatg ggtcatccca tttacattgt tcattttatc actttttgcc aaaaaaatct
     5821 agtttttccc gcagtttcga ttgattttct tctaactcca tctatgtaaa ccctttctct
     5881 ccctagtctt ggacgacttt tggaaaatct ataaagaagg ttaaacgatt ctcctccatc
     5941 tcgaaacgat aagctaattt ttcatgttct aatagactct taaccacaaa gagccccata
     6001 ccagacccct tgaccttgcg actggcattg tcagaaaaag actgggctag tttttcttgt
     6061 tcctctgagc tacagctatt ttcgataaaa agttctcctt ctctttctcc aattcgaact
     6121 aagccacctg gaacagagtg cttaatggca ttgctgatga gattagaaag aatcaacttc
     6181 ataactgatg ggtttagata agcctgctga tgggtcaaac tattgtctat ctggagctct
     6241 ctttccttgg ctagcaaggc ataatctttg accagatttt tcgtcatctg gaggaggtca
     6301 attgtttccc tatcatctcg caattcctgc acagaagaga gggaaagtat ctgcagaaca
     6361 tggtgattga gttcatccac aatccccaag gcaactccca gatactggtc tctatcctta
     6421 taacgaccga tattctctct catattttcg attaggattt tcaaactagc cagcggtgtt
     6481 ttcaattcat gagaagctcc tcgtaggaat tcgaccttca tcttctccag ctggagaatg
     6541 gcttcattct tttcattcaa gtccgcaata acagtcaaga gatgctggta gaggctattg
     6601 atttgttcct tgagattacc tatctcatcc ttagaatcca cgcgcaatcg cacttgggaa
     6661 tccaggtcca tcatccgacg ggtcacccgc ttgatttcca aaatcggtgc aacaatagtc
     6721 caagcgtaga tgtaggccac caagagggaa atcagaaagg aggccagcaa ggtataggga
     6781 agaaactgga gactgatttg ctccgcttcc ttttgtaaat ccatggaagc tagaaactgg
     6841 agaatcatag taccaccgtc ttgcgttttc acctcgcgct cctcaataaa gagagaggtt
     6901 gtctggcggt ctgtgtccag aggaagactg tccttgactt ctaacttgtc ctcggtcatc
     6961 tcacctttga cggttccctt gatatcacta gtctgggaat acaagtctaa cacttgctcg
     7021 atactctgcc tatctttccc ttctagggac tgggcaatgg ctgttgcctt ttgaccaatg
     7081 gtttcctgac gatgactcag ataagtcgaa ggaaaaagaa aataaatagc taaatgaagg
     7141 cagataacca gaacactaaa tatcgagaag gtatagataa atatctttgc aaataaacct
     7201 gttcgtttca ttttcgctcc aatttataac caacattgcg cacagtgagg atacaatcca
     7261 agtctagctt tttccgcaat ttctggatat aaacatcaat aacacggtca aagggaacct
     7321 catctgtcgc tttccagacg gcatcgataa tctgagatcg agtcaaggcc cggccttcat
     7381 ttttcactag atagtccaga atttccaact ctttggcatt gataggcact tcttgacctg
     7441 cgaggcttgc actgtagctt tcaaagtcca ccttggtatc cttgtaagaa aagattcgtc
     7501 ctgtatcgta gtagcgcttg aaaatcgcgt ccaccctcac ttttaagagg gagagggaga
     7561 aaggtttttc cagatagcca tctgccaaag aagcaaaggc actcatcttg tattcctcat
     7621 cctgaaaagc tgtcaacatc aagacaggaa cctgactggt tttacgaatc tcagctagga
     7681 cttctaagcc gttaagcttg ggcatctgga tatccagtaa aaccaaggcc acctcatagc
     7741 tagaaaattg ctccagagct tcctgaccgt ccgctgcctc aatagtttca tagccacaat
     7801 ccgtcaaata atcactgacc ccctcacgga tcatctcttc atcttctaca attaaaattt
     7861 tcatacttta actgctctct attttttatt tttcttagaa taaataccta ctctattttc
     7921 tattatagtc tcttgctggc cttttgtctg taagcaactg accactagat aaaacgttgt
     7981 gaaattcctt tctcataaat tccataactt tagtatatta tatttaagca ctaaagtaca
     8041 aagaaagcaa ctgaaagcaa tgattttcac cactgctttc ggatttattt tgaattgtta
     8101 aatagccatt cctatccact attcttgaat agaaacacaa gatgcaatct ttattccaga
     8161 ctcatttttt caaatttatt caccatccag caagagctct tttggttgtt ttctaaggag
     8221 attgcttgaa gcaagcgcca taacgagaac cactagaacc aaggcaagga caaaaatgat
     8281 gataaagtct gatgtctgaa tggaaatgtc taggctcgac aaggtcttgc taaagccatc
     8341 tacttctgca ccgccaccaa ggttagaggc ttgagccgcc ttactagcct gtttggcaac
     8401 acctgaagtc acattggcaa ggacagtgtt tccaattgca cgggcagtgt aattagctag
     8461 gaagtaagca gaaactagag cagggatagc aatcaagata gattcggtga tgaattgacc
     8521 caagatactt gcctgcttga ggccgataga gaggagaatt cccacttcct tgcgacgggc
     8581 gttgatccaa aggctgagca agagggcaag gaggagaact gagaagctca agctacccca
     8641 gaagaggagg ttggccatct tgtacatacc agagatagat tgctcaagag ctgggtagtt
     8701 agaggagctc ttgacgagtg tgtagctctt ccagttgata ccactgatgc cattcaactc
     8761 tttcataaca tcatccaagt tcttgtctgc tgttacaaag aaggttgcgt ccccataaat
     8821 ggctgtgtct tctgtgtatc cataaagttt tgcagcagtg tgaatgtctg taatagctgt
     8881 gttttcgtaa agttcttgtg agtaggttac tgctgactta ttatgaccat caaagagtcc
     8941 cttgattgtc acttcaactg tttccttggc tcctttttca ttatctgcat cgtagatatt
     9001 agagtccagt ttaaccttgt cccctacttt ccagccgtgt ttggctgcca agtccttgtg
     9061 caagaggatt ttatccttgt cgtcgttggt taagtgctct ccttcgacta gtttataaga
     9121 accagagaca aacttgtctt ctttagagga gtcattgaca cctgtaatca tcaagctact
     9181 tccaaaacgt ttggcacgat cagcagtgag attcttcttg gtttctggcg tttcaatcag
     9241 gtcatatcca gtcaaatctc cgatagcgtt gatacgtttg acataagact caatggcctt
     9301 gttttcggtg atttttttga tgtcttcacc cttgatattc ccagcaccac gaggcgttcc
     9361 ttggttgacg cgacgattga tttgcatgga gaagctattg gtgatatttt taaaggtctc
     9421 ctgagaagcc ttggcagtag ctcccttgat tgacaagccg accaaactca agctcgccat
     9481 gaggagaata atcaggaaga tgacaatcga tttgaaaaac ttccttgtaa cataagcaaa
     9541 tgcgttgtgt aacatagatt ccctttctag attttgtttt aatcattcta tcaaaataag
     9601 ctcaaattat ttactagtat tgcgcgtttc agtcagtttc ttatccttta attcaagtgt
     9661 aatatctgac gcttgtgcca cttctttact gtgagttacg acaatcacac atttacctgt
     9721 tttctgggca agtgatttga gtagttcgac aatatctcca gcagttttag gatccagatt
     9781 tcctgttggc tcatcagcta gaataactgg agcttctgag accaaactgc gagcaatggc
     9841 aacacgttgc tgttgaccac ctgataactg gagaacattc cgcttgatct ggctttcatc
     9901 caaaccaagc tcaagaagtg tattcttgct tgcctttttg ttgaccaatc ggatattttc
     9961 cagcggagaa agataatcta tcaagttata attttgaaag accagggaaa tatggtgcat
    10021 gcgatggtaa gaatagccct tcttacgaat atcctctcct tgaaaaagga tagaaccttc
    10081 aacaggacta tctagaccag caagtaggga caagagtgtg gattttcctg ctcctgactc
    10141 cccaataata ctgtaaaatt ttccgggttc aaaattataa ttgatctgat ataggactgc
    10201 ttcagcaata ttcttataac ggtaggtaac atcttgtaat tgtaataaag tcatgatttc
    10261 tccttcttaa ctaatagatg ataaaatttc tttcggtgat tttctaaata agaataggaa
    10321 acaaagggct acagataagc aactaagcag aactagaaaa acataggatt ctgcaaaaga
    10381 taagatgcta gttgataaac tgcttgcttt ggctagtgta tcttgtaagc ttgcctgatc
    10441 tccacttgct agtagagttt ggagtaggta agttgtgatt gcgtttcctg caacaaatgc
    10501 tggaagcaaa gctccaagag ataccaaaac tacctctaaa cagaattgta ggaagatcga
    10561 gctcttgcct tttccaagtg caagtaaaat ccccacttca tagacccgtt ctctcaacca
    10621 gagagacaaa accagaatta aggctccagc tcctgctatc aacatcccat aaaggaagat
    10681 ggtcaggaag gtttggaaag ttgcaactga gtctttgatt tgttcaaaag ccttgttttc
    10741 cttttcgact tggtagcctt gattttccaa ggccaagttt tctacctgct tcatgagtcc
    10801 gtccatttcc ttaggatttt ctacatagaa gcgtgctgca ctgacttgag cttcactatt
    10861 gcccaaaagg gtttggctac tttcatagtc tgtaaagact tgattttcac tgaagtcaga
    10921 agacaagcct gtgaatttct cttgtttttt accagaaaag atgccgataa tctcaaactc
    10981 tactgtttgt ccttttccag attcagactg accagcatcc aagccaatct tgtcatgaag
    11041 cgaaagaccg ttcttcttag ccaattcttc gtggataagg attttcttgg aatccccttt
    11101 ttgaaggtgt cgcccttctt ttagattgaa agccgaactg gtaaaggtta catccttgga
    11161 tgaatcctca agagccgtta agctaaccaa gttattgtct gcagctgata aatcatcacg
    11221 ctccacgctc tgctcgccag tcactgcttc cttgtctttt agttttgcga ccgtctcaag
    11281 ttcaggagag acattttcca gccccttaat cttgcttaca gatgctaggt ctgacaactt
    11341 gaatgtctga ccattctcta tcttcttaat agaaaaagat gtattgagtg atttataaag
    11401 attgctttct actgttttgt tggacttcat cagagtcaaa caggctgaaa ttccggccaa
    11461 taagaccaat aaaatcagaa ataaaataaa acttctcagt cgctttctgc tgacataagc
    11521 ccaagatctt tggattggat tcatttgtca cctccatatt tgtaagacta ttataaaacc
    11581 caaatatgaa atgtttatga aatacgaaaa aaaatatcga gtaggggata atctctagcc
    11641 cctctcacac caccatacgt gccgttcggc atacggcggt tcaactaact tttaacgcat
    11701 gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg tttttcaagg actggttttg
    11761 atatggcacg tttaagtacc gacttctgag ctactatagt agattgaaac tagaatagta
    11821 catctcttct tctaaaatat tgttagaaat cgatttgact tccctgatcg attcgtccta
    11881 ttcttatttc attttactat aattgatagt ggtcgcccca gccagatacc ttatctgcta
    11941 tccatttagg aacccctaac ttaagcaatc cccataatcg tctcgatttc ttcttccatt
    12001 gcttccagat aatcactcgt aggcgagtac gcaagcgctc atctatgcta gtgactatac
    12061 ttttcatatt tataattcat tcctttcgtt tcactcaagg cacaacacag aatgaaaaag
    12121 tgttgtgatc tttattttgt tttataataa tagtgagaaa gcctatcact actacaaatc
    12181 acggggaggt gaataagtga gtggtacagc cactacctcg catattttgt cacatcattt
    12241 aacggtacat aataagttgt accatctgaa taagttgcta caatatcatt tgcatgctct
    12301 ccttcacctt tagcaaaggt tggagctcct gctggatgat ttttatttgc ctctttcaat
    12361 ttttcaataa tggcattttt ttctgtatct tttatagtat caggattttt cactaagatt
    12421 ttgtctggat atgtcggttt agcagaaaca atttttactg ttatttcttt tttattcgaa
    12481 gcacttgtcc agtttccagc attatcttta gtatttaatt ttacagtaat tcctgaacta
    12541 ggaacttcag tagcaggttg attatcaaca ttattcaact ttaatttcaa aagagctgtt
    12601 gcatcagacg ttttatcaat cgttgtatat aatgataaat tgttattata accaatttct
    12661 tcatatttag ctgtttgtga gctacttgaa acagaactga aattatgccc actacctccc
    12721 tgattatctt caatgcttac gtctaaatga acttccccac tattatttgg cttagcaaca
    12781 actgttatag taaaataaca taaaatttgc ataaatagat tagggaaatc aaagcaactt
    12841 ctaggaatgt tttagcagtc acagtgtact ttcccagcat caagccacta taactctgca
    12901 cataaaaatg gagaagatgg ccatcctctt ctccaaatat taacttcttt acaaaccaac
    12961 tatagttgac aaagaaccta aaatcaattg ataacacaag gtcaggtcgg tcaactcttt
    13021 caactgaagc cctgtcaact cttcccattt atcaatcttg tattggagag aattgcggtg
    13081 cagatagagt tgctgggctg ttttagtgag aacagcacta ttttcccaaa gagagagaat
    13141 gatttcctga atctgatctt gatccaaaat catctggtgt agacattcct tgattggctt
    13201 caagtccacg agtctttctc ccatactcca aagatagagt tgagaaaaag tatgaacacc
    13261 ttggtgaccc tgacgccacc atgtcttgaa caaatcccgc tcagctttga ttaagtctga
    13321 tagggcttga tgtcccgtct gagaccaaac ctgacccaac atgatagaaa gacgaagtcc
    13381 aaagtcatac tcaaccgctt caatcgtatc acttaaaata tctcttacag aagtgtattt
    13441 gtcttgttga agcacgaaaa cataatcctg agctccgacc tgtagcactg tctgacaatt
    13501 cggaaaaaga gtccgcatca tatctagcca agaagccaga ttttcctgct gaaaataaga
    13561 aagatggcaa taaaccaact gaatcttttt aaaaacttgc ggtgcctgtc ccttgccctc
    13621 aaccagatag gaataccaag ggtttagcga acgagcctgc tcctgctggg tcaaaagggc
    13681 aaccaactgc ttttcacgct cgctgagccc agcttcctcc agcaaaatcc actgctgaga
    13741 agctaaaggg agcgtgagat agccctcttt ctctactggt tggtctgaaa tccgagcctc
    13801 aggaaaccag tcttgtagtt cttttgccct catgttctag ccctccactt tttggatgca
    13861 ccatgaaacc aaactctcaa gacgttccag attctcagtc atatggagat agcccataac
    13921 cgcttcaaat cccgtggaca tacgataagt cacgacatct gcatttttag cctttgtgtg
    13981 gctattggta ttgcggccac gtttgtagat ttcttcttct ttttccgtta ggacctgctc
    14041 ctccaacatg agagcaatca ggcgagcctg agccttggct gacacgtact tagttgcttc
    14101 ttgatggagt ttattgggtt tggtcatacc tttgaggatg aggtgacggc gaatatacat
    14161 agaatacacc gcatccccct caaaggctag cgcaatcccg ttaatgagat tgacatcaat
    14221 cacgtgtcca cctcactcca tccttggtat caaggagctt aattccttga gtaaccaatt
    14281 ggtcacggat ttggtctgct gtctcaaagt ctcgattggc acgcgcctct tggcgttttt
    14341 gaatcaagtc ttcaatctct gcatccaaaa cttcctcaac aaagacaatt ccaaaaattt
    14401 ctaacatatc tgcaagagct tgcttgacac ttgcatcata gttccctgag ttgatccatt
    14461 tggccatttc aaagacaact gtgataccgt tggcagcatt aaaatcttca tccatagctg
    14521 ctacaaactt atctttaaag ttttgtaact cttgggcatc cacgtttcct gtaaatggtt
    14581 gttcgtaagt attcttcaga tacttgagat tggtctcggc atcgcgaact gccttttccg
    14641 tgaagttgat aggcttacgg tagtgctggg tcgcaaagaa gaaacgaagt acttgcccat
    14701 caagagtttt aagggcatcg tgtaccgtaa tgaagttacc caaggactta gacattttga
    14761 cattgtcgat attgacaaag ccattgtgca tccagtagtt agcaaaagcc ttgcctgttt
    14821 tagcttcaga ttgggcaatt tcattggtgt ggtgtggaaa ctctaggtca gctccaccac
    14881 cgtggatatc aatggtatca cctaaaatct ctgtcgacat gactgaacac tcaatatgcc
    14941 aacccggacg tccaggtccc caaggactat cccaagaaat ctcacctggt ttggaagatt
    15001 tccataaagc aaaatctaca ggattttcct tacgagccgt ttcttcatcg gtacgacctg
    15061 aagcacctag atccaaatct tccaaggttt tattagccaa tttagcatag ttgtgggatt
    15121 tttctacacg gaaatagaca tccccttgac tctcataggc aaagcctctc tcgatcaagt
    15181 cttccacaaa acggatgatg tctgccataa actccactac acgcggatgg cgagtcgcag
    15241 gtttcacgcc taaggccgtc acatcctcac gaaaggcagc gatgtactta tccgcaacct
    15301 cctgaggcgt gataccttct tccctggcac ggttgataat cttatcatcc acatctgtaa
    15361 aattggaaat ataggcaacc ttatacccac ggtactcaaa atagcgacga atcgtatcaa
    15421 aagctaccgt cgaacgggcg tttcccacgt ggatatagtt gtacaccgtt ggcccacaaa
    15481 catacatctt gatcttgccg tcctcaatcg ggacaaattc tcgcaaatca cgagacatgg
    15541 tgtcatagat tttaatcata aatcataatc aggaaagctg aaatccaaga acaattagtt
    15601 tcatcactaa aagttcaagt aaatttcagt ccgaatatct ctacacttcg gaatcccttg
    15661 ctcctttctc attcagataa accacctgag tctgtttgac aaagccaatt ttttcataca
    15721 aacgtttggc acctacattg ctatcttcca ctgcaatctg aaattccttg tcattttgct
    15781 caattagttg gttgacgagg gattttgcta agtagcttcc atagcctttt ccacgttcag
    15841 gttccaatat tgctaaacca tagaggtaat tcgtattagt cgataaatca accgtacaag
    15901 ttccaataac ctgaccagct tttaataaaa tatatagtcg gctttctgga tctttcagag
    15961 cttcagcgac atatctatcc acaacttctc tcgattcatg ttcctctgaa aatgcctgaa
    16021 attttaattg actaatttga tcctgatacg aactatctgc taacaaaatt tcaagatggg
    16081 aaacatttgc taacggataa ggtcttctat ccttacctaa ccaagtttct gtctcttcat
    16141 cctcgattag tccccagtta ctggcaaagt caggatgatt ctctaaaaaa atacgttctg
    16201 tctgaaaagt gactgatcga atggggaaag aagctgtttc tctctcaaaa ctagtaaaca
    16261 atgcacgcgc aatcccctga cggcgatgac ctggatgaac cagtatcgtc acttctacat
    16321 cttggtcatc tgcatagaca gttaataaac caacaagttc gcctttttca taataaagga
    16381 aaaaggcggg catgtttggg tcaaaattaa gcatgttaga gagataggga tcgcgatagg
    16441 taccgtcata gttttggcaa cagttaatta cttttttcgc ctcagatagc tcctcttggc
    16501 ttaacttgtt tcttgcttga atcatatagg tatcctctac aaaccagacg atctgtgact
    16561 ggcatcttta gcctgctcga gtttattgac ataatactcc cgtttttctt cgacttcgtg
    16621 aataacaggc tcatctttct taccatgaag acggacaatc ttggccggaa taccgacaac
    16681 cgtcacatca ctaggtacat ctgctacgac aactgctgca gcaccgacct tggcattttc
    16741 accaatttcc acaggcccga taacttgggc atgggctgat atgagggctc cctttcgtac
    16801 agtcggatgg cgtttgccac agtctttccc tgttcccccg agagtcactc cgtgatagag
    16861 aagaacgcct ttttcaacaa tcgctgtctc tccaatcacc agaccagaac catggtcaat
    16921 aaagacacct gaatcaatct gggctcctgg atgaatctca atctgagtcc aaaagcgcca
    16981 aaactgactg tgcatacgag ctaagagttt gaagtcgtac ttccagagaa aatgcgagag
    17041 acggtgggcc gccaaggcct tgacacctgg ataagtcagc aaaacctcca aagtggtgcg
    17101 ggccgctgga tcattttctt ttacgatatc aatggtttcg cgccaccacc ccatacattt
    17161 ctccttttct tactctgaat cttttggtgt ttctgtaaat tctttcttag gtttgtgatc
    17221 cttgtgatga cgtgggcggt gagggcgctc agacttttca cctttttcat catgctcagg
    17281 ttttggcgga cgaggtagaa gagccttcat agaggcatcg atacggcctt tttcatcaat
    17341 cttgataacc ttaacatcaa cttcatcccc gatttctacc aaatcctcta cacgattggt
    17401 acgagtccaa gccatctcag agatatgaac aagggcatct gtcttatcaa agaggttaac
    17461 aaaggcacca aatttctcga tacgaacgac tttagcacgg taaacttcat ccactttggc
    17521 ttcacgaacc aaaccagcaa taatttcttt ggcacggtta atagcatctt ggtcactaga
    17581 gtagatagac acatttcctt cttcgtctat atcaatctta acacctgttt cagcgataat
    17641 cttgtcgatg gtttctccac ccttaccgat gacaatctta atcttgtcta catcaatctt
    17701 gatcgtatca attttcggag cagttggagc caattctaga cgaacttctg gaatggttgc
    17761 ttcaatgaca tcaaggattt caaaacgcgc tttcttggct tgagcaagag cctccgtcaa
    17821 gatttctgca gtaatccctt gaatcttgat atccatttga agggctgtaa tcccatcacg
    17881 agtacctgca accttgaagt ccatatctcc aaagtgatct tccaaacctt ggatatctgt
    17941 caatactgtg tagttatttc catctgagat aagtcccata gcaataccag ctactggcgc
    18001 cttgattggc acaccaccag ccataagggc aagagttccc gcacagatag aagcttgaga
    18061 tgaagaaccg tttgattcca aaacttctgc tactagacgg atagcgtatg ggaattcttc
    18121 caagcttggc aagacttgag caagagcacg ctcaccaagg gcaccgtgac cgatttcacg
    18181 acgacctggc gcaccgtaac gacctgtttc ccctacagaa tattgaggga agttatagtg
    18241 gtgcataaag cgtttcttgt actctggatc caaaccatca atgatttgag tttctcccat
    18301 cggagccaag gtcaagactg aaagagcttg agtttgccca cgagtaaaga gacctgaacc
    18361 atgtacacga ggaaggaagt cgacaaccgc atccaaagga cggatttcat cgaccttacg
    18421 accatcagga cgcaccttgt cttctgtaat taaacgtcgc acttctgcgt gttccatttg
    18481 ttccaagatt tcagccacat cacgcataat acggtcaaat tcttcgtggt ccgcatattt
    18541 ttcttcgtaa acggcagtca cttggtcttt cactacttga gtcgcagctt cacgggccaa
    18601 tttctcttct acttgaactg ccttttggag gtcactgttg taggctgcaa tgatttcagc
    18661 ttgcaattca gcatccacgt gaagcaattc cacttctgct ttttctttac cgacagcagc
    18721 aacgatttct tcttggaagg caatcaattc tttgacagct tcgtgccctt taaggagcgc
    18781 ttccaacatg atttcttctg acaattcttt ggcaccagac tctaccatgt tgatagcgtg
    18841 cttggttcca gctactgtca attcaagaag agattgctct gcttgttctt gacttgggtt
    18901 gatgatgatt tggccatcta catatcccac ttgtacccca gcaattggtc cgtcaaatgg
    18961 aatatctgaa atagacagtg ccaaagatga accaaacata gcagccattg gtgcagatgc
    19021 attttcatca taagaaagca ctgtattgat gacttggact tcattacgga aaccttccgc
    19081 aaacatagga cgaatcggac ggtcaatcaa acgcgctgtc aaggtcgcat ctgttgaagg
    19141 acgtccttca cgtttcataa agccaccagg aaacttccca gccgcataca ttttttcttc
    19201 gtagttgact tggaggggga agaaatcccc agttgccatt ttcttagaca taacggcagc
    19261 agtcaagaca gttgactcac cgtaacgtac gacaacagag ccatttgctt gcttagcaac
    19321 ctgaccagtc tctacaatta actcacgacc cgcaaaagtc gtttgaaaca cttgttttgc
    19381 cattttaatc ccctttggat tgatgaaatt atacgccttg cctacaaaga tcaagatacc
    19441 aaggacgtca aaagcaaagt aaaaatagga aactgacgaa gtcttcgatg aagacaaaac
    19501 agtttatctt ttttacacag cttttcggcc gtgttcaatt acacaagata ttttggacgg
    19561 ttcggcttgc cgaacatttc tgtagaaaaa taggaaggtg acgtcgcact cgacgagtgc
    19621 taggaagctt atcttttttc ctaagaaatg agaccaaaat tcaattactc aagatgctaa
    19681 gccgtcaagc aactcaaagg aaaataggaa atcgaacgac ggagcgactg ctcctaggca
    19741 gatttatctt tttccacaga gttgtaggcg tgttcagttt tcaagataca tcattagaaa
    19801 gatttaatat taaagtatct aaacctttca cgccaatcgc tatcgggcga ttagctaaat
    19861 gctttactaa ctctttcgtc aaataacatc gatttgactc actcgtgtcg ttaaatctta
    19921 cagtttaaat gcattgtatt atttaatacc ttcatctttg tatcaagtac gtacagaatt
    19981 tattttatca tatttttctt aaaaagtgag gtctttacca ttaaaaagga accattcccc
    20041 tcacctgaga agaatggttt gcttttatta tcctagagac tggtgattaa acaaggcatg
    20101 ggttgcttga tggatgtatt ttgctgtatc agcattattc atcgtataga gatgcacacc
    20161 ggcaacatcc tgagttacca agtccacgat ttggtccact gcataggcaa gtcctgctgc
    20221 tctgagcgac tcagggtcat gctcatactt gtctaagatg gctttaaatt tgcgtggaag
    20281 atggatattc tcacaagtct tcaagagtcg gagagcctga tttcgattca gaattggcat
    20341 aattcctgca tgaatgggaa catcaatccc agccaagatg cacttgtcct gaaaatcata
    20401 gaagcgctca ttgtcaaaga agagctgagt tacgaggctc gaacagcctg catccacttt
    20461 cttcttaaga ttttgaatat ctgaaatctg atttggcgaa tctggatgcc cttctggata
    20521 gcaagctcca ataatatcaa agtgaggggt ttgttccttg ataaactcaa tcaagtcggt
    20581 tgcatagcgg aaatcctttt gtggttccac gtctggaata atatccccac gaagagccaa
    20641 gattttctgc accccaactt tgtccaagtc agcaatagtt tcagcaacct tgtccttagt
    20701 tagataaata gctggcaagt gggcaatggt cggaatcgcc aaatcatttt ggataaagtc
    20761 agccaaacga accgtcgttt ccttgatatt aaatttatta ttgctggcag ttacactgat
    20821 aaaatgggga gccaactcct gcatatcctg caaggctgaa ataatgttac cattacccac
    20881 ggctgggttt ggagggaaca cttcaaatga gagtgacggt gtttggcgtg acatatgtaa
    20941 taaccttttc tagttgattt ctttttgaac aaccactgta tggagagaaa tccaatctta
    21001 caatttttca cgcgcagctt tagctgcttc aacaaggcgg atcaagcttt cttttgtttc
    21061 tgggatacca cgtgttttca aaccacagtc agggttgatc caaactttct tgcttggcac
    21121 tttagcaagg atggcttcga ttgtgttgtc gatttcgcct tcatttggta cacgaggtga
    21181 gtggatatcg taaaccccag gtcccacttc tgtttggaag tttttcgctt tgagttcgtc
    21241 caagatttca aggtttgaac ggctggcttc aaaggaaata acgtctgcat ccatgttatc
    21301 gatagctggg atgatatctg taaattctga gtaacacatg tgagtgtgga tttgtgtgtc
    21361 tgacgctact gttgagtgta ccaagcggaa ggcaggaatt gcccagtcaa ggtaatcttc
    21421 gtaccagtca ctacgacgga gtggcaattt ttcacgaaga gcagcctcat caatttggat
    21481 gattttcaca ccagcagctt caaggtcaag cacttcatcc ttgatagcaa gggcgatttg
    21541 aagagtagaa tccttgatag agatgtcttc acgtgggaat gaccagttaa ggatggtaac
    21601 aggtccagtc aacatacctt taacaggttt gtttgtacga ctttgtgcat agctagacca
    21661 tttaacagtg atagggttaa gacgagtgac atcaccccag atgattggtg gttttacccc
    21721 acgcataccg tatgattgta cccatccatt tttagagaag aggtatcctg acaagttttg
    21781 accgaagtac tcaaccatgt cattacgctc aaattcaccg tgaacaagga catcaaagtc
    21841 aatatcttct tgccacttga tccattcgtc aatcgtttca gcaaggaaag catcgtactc
    21901 tttttgagac aattcacctt tacggtaagc caaacgtttg gcacgaactt cttttgtttg
    21961 agggaatgaa ccaatcgttg ttgttggaag agctggaagt ttgaaagctt cttcttggat
    22021 agcttcacgt tctgcaaagg ctggcaaacg agtgtagtct gcgtctgtca agccagcgat
    22081 acgcgcacga agttcagcat tttcaccaac acgctcagtc gcaaagagtt ctttgttggc
    22141 tgcaagagct tctgaacctt gaccattgcg gatagcatcc aagtcacgga tttcatccaa
    22201 tttttcaact gcaaaggcaa agtggttcaa gagtgctggt tcaaattctt cattagcagt
    22261 tgtaaatggc acatgaagaa gtgagcaaga gcttgtcaaa acgatgtttt cagctgggat
    22321 ttgctcaaga acagccaagc tcttttcgta gttgttgcgc catatgtttt taccattgac
    22381 aatacctaca tagagagtct tgtcagctgg gaagccacct ttaactagtt caagagtttt
    22441 cttaccttca acaaagtcaa gaccgatagc atctactggt aagtttacaa ggtcagcgta
    22501 tacgtcacga acatcaccga aataagtttg aagcaagact tcaagacctt ttttgtcagc
    22561 caagagtttg ttgtaaaggt tcaagaagag agctttttct tcagctgtca agtcttttac
    22621 aagagccgct tcatccaatt ggatgcgagt cgcaccaagt tcagccaatt tagcaaaaac
    22681 ttcttggtaa gcagccacta agctatctac gaagtcgtct gctttcacgc cttcttcaaa
    22741 gtctgacaat tgaaggaaag tgaagggacc tacaagaaca ggacgagtgt tcaatccaag
    22801 ttctttggct tcttggaact catcgaaaat cttgtgacca gccaatttta cttgagtgtc
    22861 tttttcaaat ttaggaacga tgtagtggta gttagtgttg aaccatttct tcattggaag
    22921 ggcgcgaacg tccccttttt ctccctggta accacgtccc aaagcgaagt agcgctcaag
    22981 gtcagacaag tccaagtttt gaacggatgc aggcaccacg ttgaaaagga aagccgcatc
    23041 taggaagtta tcatagtgag aaaagtcatt tgatggaatt tcagtgatgc ctttttcttt
    23101 gacaatgttc cagtgtttag cacgcaagtc ttttgctgct gctaaaagtt cttcttctga
    23161 gatttctttt ctaaagtatt tttcagttgt aaattttaat tcacggaatt cgcccaaacg
    23221 agggaaaccg atgattgtag ttgacatgat gtgtcctcca aaatttgttg ttgaaactat
    23281 cttaacagaa aagaaagcgt ctgtataatt gtaaaaaatt agggtttgat atagtttgaa
    23341 actatatatc tgtttcggac aaaagaaaaa gacttgaagc aaacgtctca aatcctttgt
    23401 aattcttact ttacagctat attccaatta gaatactaaa acatgttatt agtaattctt
    23461 ataagtgact atgacctgtt attagaaaag actataactg attctagtca actttttccc
    23521 tgttcaagtg ggacgattgc tagtgtcttt cctaaactgg ctaggacttt taagactgta
    23581 tccaactgag gactagtctt tcctgtctcc atcctagcta tgacaggctg gcttattcca
    23641 ctgacttctt ccagcttttt ctgactgatt ccttgttcat acctagcctc aatcaactcg
    23701 ctcatgatag ccactcgcat atcactttca aggatttcct ccttgctaaa gagctcagat
    23761 ggacatcctt ccaattactc ccaatagcac tattcttcat cacttaaccc tcttttttta
    23821 cgtctatgta tttttaaaaa aatgagcgaa ttatgattcg atagattgac cagtgggttt
    23881 aaagttggtg ctagcctatt tcttaagcga ttttcctttt ctaggataaa gcagatcctg
    23941 cttgcttaac cccaattttc cacgatgaat ccaatagtaa atggttgaaa ttcccacgtt
    24001 aaccccttta gccatcacca tcatttcagg cgaaaatttt tggttatgta tagtggagaa
    24061 tcttttcctt tagtttctta agactgttga gcgtagtcgg cagaataaat ctctttgaag
    24121 cgcccttttc caagacattg tcggactgtc ccacgcttga tttcagtgtg gatagtttga
    24181 ggagcttttc caagtagaga ggcaatttct ctatttgatt ttccttcttt tttccatcgt
    24241 tcgattaagc gacggctatc gattgtcaaa tgtttgcctt ttgtagtata attgtcttgc
    24301 atttctgtgc cttttaatca tttcaatctt aaattggact ttttttactt gggttgtact
    24361 taatctataa ggaagacaag aaaaagaata tcaatcaagt aaagtcacaa agtcacatta
    24421 gctccgagca accattgcaa attgaggtac tcacacaatg attaaaacat ttctctctgc
    24481 cctttcggtc attctctttg ttatccctat catagcttat tctttttttc catcttctaa
    24541 tcttaatatt tggctatcta ccagacctat cttggcacag atttatgcct tccccttagc
    24601 tactgcaact atggcttcta ttttaagttt cgtatttttt tccctatctt tttacaagaa
    24661 aaataaacaa atacggtttt actctggcat tttgctctta ctatcgctca tattactatt
    24721 atttggaaca gataaaaccc tttcttctgc accaaataaa actaaaacct taaaattagt
    24781 aacttggaac gtcgctaatc aaatagaagc acaacatatt gagcgaattt ttagccattt
    24841 tgatgccgat atggctatat tccctgaact agctaccaat atcagaggtg agcaagaaaa
    24901 ccagagaatc aaactattgt ttcatcaagt tggactttct atggccaact atgatatttt
    24961 cacttctcca cctaccaata gtggaatagc tcctgtgact gtgattgtca agaaaagtta
    25021 tggtttctat acagaagcta aaacttttca tacaacacgg ttcgggacaa ttgtattaca
    25081 ttcgagaaaa caaaatatac cagatatcat tgccttgcat actgctcctc ctctgccagg
    25141 tttaatggaa atctggaagc aagacttaaa catcattcat aatcaattgg cttcaaaata
    25201 tccaaaggct attattgcag gtgattttaa tgcaactatg cgtcatggag cacttgcaaa
    25261 aataagctct catagggacg cattgaatgc acttccacct tttgaaagag gaacttggaa
    25321 tagccaaagt ccaaaacttt ttaatgcaac gatagatcat atcttattgc ctaaaaacca
    25381 ctactatgtt agagacttag acattgtaag ttttcaaaac tctgatcata gatgtatttt
    25441 tacagaaatc acattttaat tattttatat aaaatcaccc ctctagtgtt cataaactag
    25501 agggggaatt tgtatcctac tatcgtttaa cgcacttctg cattcacttt ttcttcgagc
    25561 gatgcttgga ttttttccat atagcgtgcg acttcttcgt ccgttaagct atcttctgga
    25621 ttttggaagg tcaagctata agccatggac ttcataccaa gtcccaattt ctcacctgag
    25681 aagacgtcaa agagtttgat atctgtcaaa cgtttcacgc cggcagcttg gatagcatct
    25741 acaacttctt gatgagtcac ttctgccttg aggagaaggg caacgtcacg gctgactgct
    25801 gggaatttgg tgatttctac aaatggagtc gctggctgaa gcgcagcttc gatagctgaa
    25861 aggttaagct cagctacata cgtttctgga atatcgtaag ccttggcagt gactggatgc
    25921 acttggccaa ggaaaccaag aacttggtca ccgagtgaaa tcacggctgt acgacctgga
    25981 tgaaggctag cgatttcaga tgttgctgta taggttactt ggagtcccaa acgagtaaat
    26041 agggcttcaa ggattccctt agcatagaag aaatcaactg gaactgctgc tgtttggaaa
    26101 tctttttcag caaccaagcc tgtcaaggca aaggcaaagc tgttgatctc atttggaagt
    26161 tcttcttttg gattacctgt ttgttcaaag acttttccaa tctcataaag ggccaagttt
    26221 ttattcttac gagccacgtt gtaggcaacg gtatcaagga tccctgaaat catattttga
    26281 cggaggactg aacgatccac agtcattggc cacatgagtt cagtaaggtt acttggttga
    26341 gctgtgaact caactgcttt ttcaggagtt gtcagagcat aggtgataat ttctgtcaaa
    26401 cctgctcctt cagcaatggt acgaacttga cggcggagtt tttgtgtcac agtcaattca
    26461 ccagctgtac catcgtcttt tggaaggctg gttggcaagc ggtcatatcc atagatacga
    26521 gcgatttctt caaagagatc agcttcgatt gtgatatccc aacgacgacg tgggactctg
    26581 actgtaaagc tgtctgcatt tccagaaaga ccaaagccaa gacgacggaa gacgtcttct
    26641 acatcagcat aagacagctc agttccgagg acacggttaa catcagcaag ggttgaagaa
    26701 acttctacat ctgaagtatc aagctcaccc gctgaaacga tgcccttacg caccgtcgca
    26761 cctgcaagtt ccgcaatcag gctagctgcc gcatcaaggg cttcattaac tgttgccaca
    26821 ttaattcctt tttcaaagcg agaagatgac tcagaacgaa ggttcaggcg accacttgtc
    26881 ttacggatag atttgccatt gaaaacagca gcttcaagga caacacgact agatttttca
    26941 gagatttctg ttgcttgacc acccatgaca cctgcaaggg ctactggctt gtctgcgaca
    27001 gtgatgacta ggtcattcac gtccaagtca cgttcttcac cgtccaaggt aaccaatttt
    27061 tcaccagcac gcgcttcacg cacacggatg tcagtccctt caaatgtgtc caagtcaaaa
    27121 gcatgcatag gttgaccaaa gtagagcagg atgtagtttg tcacgtctac aacgttattg
    27181 atgggacgga tgccttcgtt catgagaagg ttttgcaacc attgtggact tggtgcgatg
    27241 gtcacattgt ccaagatacg ggccgcatag taaggtgcct tgtctgtctc aatgcccaca
    27301 gaaagggcat cggctgcaac ttggtctgtt tctgttaaag taaattcttt gaagttgact
    27361 gccttgtcat atatggctgc tacttcgtgc gcaaccccac acatagaaag ggcatctgca
    27421 cggtttggtg tgatagacag ttcgatgatt tcatcatcca agtctaggta agaaaagact
    27481 tcctcacctg gcacggcatc ttcaggcaag atttggatgc catctgcgaa ttccttaggc
    27541 acaactgagt cagaaattcc caattcacca agtgaacaga tcattccaag tgactccaaa
    27601 ccacggattt ttcctttttt gattttgtag ttatcagcga tacgagctcc tggaagagcc
    27661 accatgacct tgatcccagc acgcacattt ggggcaccac aaacgatctg acgctcttct
    27721 tcttcgccaa cgttaatctg acaaacatgg aggtgagtct ctggcacatc ttcgcaagac
    27781 aagacctcac cgacgacaat ttttgagaga ccagcagctg gtgattcgac accctctacc
    27841 tcgatccctg tagttgacat tttttcagcc aactcttgtg atggcacatc aatgtccacc
    27901 aattctttta accatttata agatacaagc ataatttagt tctccagaat gaccattgcc
    27961 acactggttc ttttcctttc ctatcatttc aatagaagaa tcctcttctt accttaattt
    28021 ctttctcagt aaccaatccg tatctacttt ttgaccaacc ataaaatgat gttggctaaa
    28081 tttttcaaaa ccatatcggt tataaaacgc ttgagctttt gtattatgct cccaaacacc
    28141 taaccaagcc caagaaaaac tattttttgt agcaagttca agtgcgaatt caaacagttg
    28201 cttacctagt ccaaatcctt ggaatttttg tagcacatag aggcgttgaa tttcaaaagc
    28261 gtcctctaat tctctctcag tttgagcact tccccagttg actttgagaa aaccagctat
    28321 ctcctcctca tgcataatga aataggtttc agagtcagga tttcccaact cagttgacaa
    28381 agttttcaga ctataagcct cttcaaagta ttcctgtaac tgctcttccg tattatcata
    28441 cgcaaaggtt tgtttggcaa ttttagccaa cacctcaaca tctgccattt ctacttttct
    28501 aatcattatt taaactgttc tgagaagcgg acatctcctt ggtagaatcc acggatatcg
    28561 ttgattccat aacggagcat agctacacgc tcttgtccaa gaccaaaggc aaagccagag
    28621 tatacagtcg catcgatacc actcatttca aggacacgtg ggtgaaccat accggccccc
    28681 ataatttcga tccaacctgt tttcttacat acgttacagc cttctccacc acatttgaag
    28741 caagaaacat ccacctcaac agatggctct gtgaatggaa agtaagatgg acgcaaacga
    28801 atttgacgct cttcaccaaa cattttttgg acaatcaact gaagcgttcc ttgaagatca
    28861 gccatagaga tatttttccc aactaccaag ccttcgattt ggtggaattg gtgactgtgg
    28921 gtcgcatcgt ccgtatcgcg acggaagaca cgccctggcg agatcatctt caaaggacct
    28981 ttagaaaaat catgggcatc catagcacgc gcctgaactg gagacgtgtg ggtacggagc
    29041 aagatttctt cagtgatata gaaagtatcc tgcatatcac gagctgggtg gtcttttgga
    29101 aggttcatac gttcaaagtt atagtagtct tgctccactt caaaaccatc cacgacttga
    29161 taacccatac cgatgaagat atcttcgatt tcttcactgg tttgtgtcaa aacgtgacgg
    29221 tgaccagtcg caactggacg acctggaagc gtcacatcga tactctcgct agccagttga
    29281 gacgcgactt tcttttcttc caagagctta gctgtttctt caaaagcagc agtcaagaca
    29341 tcacgagctt cattgacgtg tttcccgatg attggacgca tctcagcaga aacatctttc
    29401 atccctttga ggatttcagt gagcgaaccc tttttaccaa ggacagagac acgcaaatct
    29461 tgcatctctt tttcatttcc agcagtaatc tgcttcaagc tagccagcgt ttcttcgcga
    29521 agcgctttta attgttcttc aatagttgac atatttcctc catcagtctc tcgtagataa
    29581 aaagaaaacc acatgccaaa aactccactc ggagcgttga cacgcggtac catccgtttt
    29641 catctgacaa gtcagacctt catttctaaa tccatgcgca agtgaattca cccagctttc
    29701 atatagagag cttgcagtca cggctctcct ccctgatata cttcccttgg gctactagtc
    29761 tttcagattc ctattcaatt actacttagt ttatcagatt tttaccattc ttgcaagacc
    29821 tatcttactt ctgcttgtta gcttattctt atctaacttt atagcggatt gaaataagat
    29881 ga
//
LOCUS       DAVHSH010000019        29754 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000019 DAVHSH010000000
VERSION     DAVHSH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.019"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            425..1270
                     /locus_tag="VVR08_001023"
     CDS             425..1270
                     /locus_tag="VVR08_001023"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU6074956.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1417..2478)
                     /gene="dinB"
                     /locus_tag="VVR08_001024"
     CDS             complement(1417..2478)
                     /gene="dinB"
                     /locus_tag="VVR08_001024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU6074957.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2826..5150
                     /gene="pflB"
                     /locus_tag="VVR08_001025"
     CDS             2826..5150
                     /gene="pflB"
                     /locus_tag="VVR08_001025"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU6074958.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5517..5735)
                     /locus_tag="VVR08_001026"
     CDS             complement(5517..5735)
                     /locus_tag="VVR08_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074959.1"
                     /translation="MMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5831..6069)
                     /locus_tag="VVR08_001027"
                     /pseudo
     CDS             complement(5831..6069)
                     /locus_tag="VVR08_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6062..6346)
                     /locus_tag="VVR08_001028"
     CDS             complement(6062..6346)
                     /locus_tag="VVR08_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074960.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(6958..7128)
                     /locus_tag="VVR08_001029"
     CDS             complement(6958..7128)
                     /locus_tag="VVR08_001029"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6074961.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7943..9166)
                     /locus_tag="VVR08_001030"
     CDS             complement(7943..9166)
                     /locus_tag="VVR08_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU6074962.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9334..10656
                     /locus_tag="VVR08_001031"
     CDS             9334..10656
                     /locus_tag="VVR08_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6074963.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10658..12544
                     /locus_tag="VVR08_001032"
     CDS             10658..12544
                     /locus_tag="VVR08_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU6074964.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYMRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12712..13056
                     /locus_tag="VVR08_001033"
     CDS             12712..13056
                     /locus_tag="VVR08_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6074965.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            13066..14478
                     /gene="lacG"
                     /locus_tag="VVR08_001034"
     CDS             13066..14478
                     /gene="lacG"
                     /locus_tag="VVR08_001034"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6074966.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14547..16226
                     /locus_tag="VVR08_001035"
     CDS             14547..16226
                     /locus_tag="VVR08_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6074967.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDISAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWTFPGPLGLLIGTNF
                     QLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIIPGEIDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGANLTEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(16351..17790)
                     /locus_tag="VVR08_001036"
     CDS             complement(16351..17790)
                     /locus_tag="VVR08_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6074968.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFTMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17794..19143)
                     /gene="trkA"
                     /locus_tag="VVR08_001037"
     CDS             complement(17794..19143)
                     /gene="trkA"
                     /locus_tag="VVR08_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU6074969.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19332..20180
                     /locus_tag="VVR08_001038"
     CDS             19332..20180
                     /locus_tag="VVR08_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU6074970.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20195..20743
                     /locus_tag="VVR08_001039"
     CDS             20195..20743
                     /locus_tag="VVR08_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU6074971.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            20750..20962
                     /locus_tag="VVR08_001040"
     CDS             20750..20962
                     /locus_tag="VVR08_001040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074972.1"
                     /translation="MKIKEKTRKQVAGCSKHGFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            21064..22746
                     /locus_tag="VVR08_001041"
     CDS             21064..22746
                     /locus_tag="VVR08_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6074973.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQIQLQTELVKETPALQSLFILEEVSFSYNDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVNEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            22731..23561
                     /locus_tag="VVR08_001042"
     CDS             22731..23561
                     /locus_tag="VVR08_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6074974.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            23754..24257
                     /locus_tag="VVR08_001043"
     CDS             23754..24257
                     /locus_tag="VVR08_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU6074975.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPDKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      24311..24545
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            24710..25273
                     /locus_tag="VVR08_001044"
     CDS             24710..25273
                     /locus_tag="VVR08_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6074976.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TPLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            25287..25913
                     /locus_tag="VVR08_001045"
     CDS             25287..25913
                     /locus_tag="VVR08_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6074977.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            25941..26330
                     /locus_tag="VVR08_001046"
     CDS             25941..26330
                     /locus_tag="VVR08_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU6074978.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            26335..26784
                     /locus_tag="VVR08_001047"
     CDS             26335..26784
                     /locus_tag="VVR08_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEU6074979.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            26912..27499
                     /locus_tag="VVR08_001048"
     CDS             26912..27499
                     /locus_tag="VVR08_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU6074980.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            27889..29496
                     /locus_tag="VVR08_001049"
     CDS             27889..29496
                     /locus_tag="VVR08_001049"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU6074981.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         8864 a         5185 c         6303 g         9402 t
ORIGIN      
        1 ttcaagagcg atgagacagt cttggttgag ctgtcgaaaa gacagatcta agagttcaaa
       61 accagcttta ttatttgaaa aagtgagtgg tttaagaaca gttttcctcg aacattcaag
      121 gctgtaacat cgtgtttatt tttagcgaca tcaatgccca cataaagcat gggagtacct
      181 ccagatatag tatttcaagt ctacttggtt atccacgaac tttttgcctt gttaccttag
      241 acgagatcaa acgtctatgt gttatcaaac tcattaccaa ttgaaacaaa agctgtggtt
      301 agagcctttc ggaaatcgtc aagcgattgg aggaaatgaa ctaatccaca gtggcttatt
      361 ccaagtatac cacttgggct ttggcagtag ctaactgcgc taattataat atagggagta
      421 atctatgtat cttattgaaa ttttaaaatc tatcttcttc gggattgttg aaggaattac
      481 ggaatggttg ccgatttcca gtacaggtca cttgatttta gcagaggaat tcatccaata
      541 ccaaaatcaa aatgaagcct ttatgtccat gtttaatgtc gtgattcagc ttggtgctat
      601 tttagcagtt atggtgattt attttaacaa gctcaatcct tttaaaccga ctaaggacaa
      661 acaggaagtt cgtaagactt ggagactatg gttgaaggtc ttgattgcta ctttaccttt
      721 acttggtgtc tttaaatttg atgattggtt tgatacccac ttccataaca tggtttcagt
      781 tgctctcatg ttgattatct acggggttgc cttcatctat ttggaaaagc gcaataaagc
      841 gcgtgctatc gagccaagtg taacagagtt ggacaagctt ccttatacga ccgctttcta
      901 tatcggactc ttccaagttc ttgctctttt accagggact agccgttcag gtgcaacgat
      961 tgtcggtggt ttgttaaatg gaaccagtcg ttcagttgtg acagaattta ccttctatct
     1021 tgggattcct gttatgtttg gagctagtgc cttaaagatt ttcaaatttg tgaaagccgg
     1081 agaactcttg agctttgggc aattgttttt gctcttggtc gcgatgggag tagcttttgc
     1141 ggtcagcatg gtggctattc gcttcttgac cagctatgtg aaaaaacacg acttcaccct
     1201 ttttggtaaa taccgtatcg tgcttggtag tgttttgcta ctttacagtt ttgtccgttt
     1261 atttgtataa gaaaaacctt gaaggggcaa ctcttcaagg ttttatactc ttcgaaaatc
     1321 tcttcaaacc gcgtcagctt tatctgcaac ctcaaaacag tgttttgagc agcctgcggc
     1381 tagcctccta gtttgctctt tgattttcat tgagctttaa aatccagtca tggtaatccc
     1441 caataggcgg acacctcttt ctttcttgct taattcttca tagagttgca gggctatttg
     1501 gcttatctga ctagcatctt gtgttttttg agcaagactt tttcgtttgg taagagttga
     1561 aaagtcctcg tagcggattt tcaaaatgac aatttttcca gctttttctt gttgatgtag
     1621 attgagagcg actttttctg atagaagagt cagctctttt ttgatatctt cctcagcaag
     1681 gagaatcttc ccgtaggttt tctccttgcc gattgattta cggatgcgat tggatttgac
     1741 tggagagttg tgaatgccac gagcctttcg atacagatca tagcctagtc taccaaaacg
     1801 gtctattagg gttacctcag gaacttcaag taaatcagca ccagtaaaaa cgcccatttg
     1861 atgaagacgt tctactgtct tttttcctac tccatgaaat ttggaaatat ccatttgttt
     1921 gagaaaatcc tcagcctgtt caggtagaat cactgtcaaa ccatgtggtt tttgataatc
     1981 actcgccatt ttagctaaga atttgttgta agaaacgcct gcggaagcag ttagatggag
     2041 ttcttgccag atatcttttt gaatgaggcg agcaattttg accgctgact tgataccgag
     2101 tttattttct gtcacatcca aataggcttc gtcaatgctc atgggttcaa tcaaatctgt
     2161 atagcgctta aaaatagctc gaatctggag tcccacagac ttgtatttct cataattccc
     2221 tgagataaag acagcctggg gacaacgttc ataagcttcc ttggaactca tggcagaatg
     2281 gacaccaaaa gctcttgcct cataactaca ggtagaaacg actccccgtc cacctgtttg
     2341 ccgagggtcg cttccaataa tgacaggttt tcctctgagt ttaggattat ccctgatttc
     2401 cactgcagca aaaaaggcat ccatgtcaat atggatgatt tttcttgaca aatcatttaa
     2461 caaaggaaaa atcaacatgc ctagcacctt tttatactct tcgaaaatct cttcaaacca
     2521 cgtcagctct atctgcaacc tcaaaacagt gttttgagca atctgcggct agcttcctag
     2581 tttgcttttc gatttccatt gagtgttact gcttattttc ttttattata cccttttttc
     2641 tgaaaaaaag aaaaaaggac tttatttttt caaaaatata atacagtttg aaataaaata
     2701 tagactgttt tagaaaagaa agtgtaaaaa tagggaattt tcacttgttg aaatcggtta
     2761 ctatatggta tacttgtctt atgaatgtaa cagatgactg ttactagaaa aaagaggaca
     2821 ttaatatggt tgttaagaca gttgttgaag cacaagatat ttttgacaaa gcttgggaag
     2881 gcttcaaagg cgtagattgg aaagaaaaag caagtgtatc acgatttgta caagctaact
     2941 acacacctta tgatggagac gaaagcttcc ttgcaggacc aacagagcgt tcacttcaca
     3001 tcaagaaaat tgtagaagaa actaaagcac actacgaaga aactcgtttc ccaatggaca
     3061 ctcgtccaac atctatcgct gatatccctg ctggatttat cgacaaagaa aatgaagtta
     3121 tcttcggtat ccaaaacgat gaactcttca aattgaactt catgccaaaa ggtggtatcc
     3181 gtatggctga aactactttg aaagaaaatg gatacgaacc agacccagct gttcacgaaa
     3241 tcttcactaa atatgtaaca acagttaacg acggtatttt ccgtgcctac acttcaaata
     3301 ttcgtcgcgc tcgtcacgca cacactgtaa ctggtcttcc agatgcatac tcacgcggac
     3361 gtatcatcgg tgtttacgca cgtcttgctc tttacggtgc agactacttg atgcaagaaa
     3421 aagtaaatga ctggaatgca atcaaagaaa tcgatgaaga aacaatccgt cttcgtgaag
     3481 aagtaaacct tcaataccaa gcattgcaac aagttgttcg cctgggtgac ctttacgggg
     3541 ttgatgttcg caaaccagcg atgaacgtga aagaagcaat ccaatgggtt aacattgctt
     3601 tcatggctgt ctgccgtgtg attaacggtg ctgctacatc tctaggtcgt gtaccaatcg
     3661 tattggacat ctttgcagaa cgtgaccttg ctcgtggtac atttactgaa tcagaaatcc
     3721 aagaattcgt tgatgatttc gttatgaaac ttcgtacagt taaatttgct cgtacaaaag
     3781 cttatgacca attgtactca ggtgacccaa cattcatcac aacttctatg gctggtatgg
     3841 gtaacgacgg tcgtcaccgt gttactaaga tggactaccg tttcttgaac actcttgaca
     3901 acatcggtaa ctctccagag ccaaacttga cagttctttg gactgacaaa ttgccataca
     3961 acttccgtcg ctactgtatg cacatgagcc acaaacactc ttctatccaa tacgaaggtg
     4021 taacaacaat ggctaaagac ggatatggtg aaatgagctg tatctcatgc tgtgtgtctc
     4081 cacttgatcc agaaaatgaa gaacaacgcc acaacatcca gtacttcggt gctcgtgtaa
     4141 acgttcttaa agcccttctt actggtttga atggtggtta cgacgatgtt cacaaagact
     4201 acaaagtatt tgatatcgaa ccaatccgtg acgaagttct tgaatttgaa tcagttaaag
     4261 cgaactttga aaaatctctt gactggttga ctgacactta cgtagatgcc ttgaacatca
     4321 tccactacat gactgatagg tacaactacg aagctgttca aatggccttc ttgccaacta
     4381 aacaacgtgc caacatggga ttcggtatct gtggatttgc taacactgtt gatacattgt
     4441 cagctatcaa atacgctaca gttaaaccaa tccgtgacga agatggctac atctacgatt
     4501 acgaaacaat cggtgactac ccacgctggg gtgaagatga cccacgttca aacgaattgg
     4561 cagaatggtt gatcgaagct tacacaactc gtctacgtag ccacaaacta tacaaagacg
     4621 cagaagctac agtatcactt ttgacaatca catctaacgt tgcttactct aaacaaactg
     4681 gtaactcacc agttcacaaa ggtgtatacc tcaacgaaga tggttctgtg aacttgtcta
     4741 aacttgaatt cttctcacca ggtgctaacc catctaacaa agctaaaggt ggttggttgc
     4801 aaaacttgaa ctcactttct agccttgact ttagttatgc agctgacggt atctcattga
     4861 ctacacaagt atcacctcgc gctcttggta agactcgtga tgaacaagtt gataacttgg
     4921 taacaatcct tgatggttac ttcgaaaacg gtggacaaca cgttaacttg aacgttatgg
     4981 acttgaacga tgtttacgaa aagatcatgt caggcgaaga cgttatcgta cgtatctctg
     5041 gatactgtgt aaacactaaa tacctcactc cagaacaaaa aactgaattg acacaacgtg
     5101 tcttccacga agttctttca atggatgacg ccttggatgc attgagctaa tcaagttctt
     5161 gaataataaa aaggaaccct cggtcaatcg actgagggtt ttgtgcttgg gatagtgtga
     5221 gcaattcctt tgacgcaata tgcaatgttt ttgggaagga atagtggacc gaatctgaaa
     5281 tatagtagat tgaaactaga atagtacacc tttatttcta aaacattctt agaaatcgat
     5341 ttgactgtcc tgatcgattt gtcctattct tatttcattt tactatagtc cactgaaacg
     5401 tctcaaacag cgctagaaat tgactggaat tctctaagcg atttgttcag attttatttc
     5461 attccatcat aaaaataaga cgactggcta attgacaatc atcttgtttg atactgttaa
     5521 taaaattcgc gaagtttatc ttgattttct ttaaaaaatt tttctaacca atccatacca
     5581 taagcataac taaaaccttc taatagaaca gagaggtcaa tagtatcaaa tcccatgtct
     5641 tttaaatatt taaaggtatc gaatggtgaa tgaaagtttt tgtatttaat aattgcacca
     5701 atatctttca aatcctgctc tctgatactc atcatcttca ttcctaacac atactcaata
     5761 gggactacta aaacggtcag attctcaaat gagtacaagg attcgcataa acttaaggga
     5821 ggttgtttgt tcatatttgc tttgcaacat gattgttgag ccataactct tcgtggatgt
     5881 taagattaaa ctgttttcct acacgagcaa taatttcatt gattttctga ttttggtcat
     5941 aaaaagcatc aacatcttgt gtggcacgta aaccatgata ttctaagaca taaccataat
     6001 tgttaaagtc agattttcct gaattaattt cttatttagg gcttggaaga ccggtttcat
     6061 tttatccatg tttgtatttc tccatcaatt tttgaacatt ggttaactta gcaggtttat
     6121 ttaatgaaat cacatattta tgagttggag tatgctcttg aaaggcatac ttcaagctaa
     6181 ttttttgaaa acgggttagt tctttggagt ctagcaactt ttctacatct tggtttgtta
     6241 aataagaata gtcttcaaaa ataacttttc gcaaatagcg aaaccaatgg cttgcgttga
     6301 attgtgattg tttggatgcc tgtatcatat aatcgtacca atccattgtc ttcctcctat
     6361 aaaatttagt ttatattatt gtagtttata ttcaaaaatg tagtttttct taattagctc
     6421 gtatctatag gatgatactg aaaatcttct tgttgcttta aatcacaatc gaaaaattct
     6481 gtttttcatc ttagaaaaga atgtttagaa atgtaaaatg aatctttttt cttatccgaa
     6541 aacattacta aagtatataa tttaggaagt caattctgta tgataatgtt tgtactatcg
     6601 tcgagttttt gcttgattgc ctaacgagat aaattttaga agaattttcg gtgtgatttg
     6661 acaagcttct gactggaagg atagttacac tagtattgtt tattaaaatg agcagataga
     6721 gaaaatttgg aatctatttg cttattatca atcgtttttt tagcttattt gtcttagatt
     6781 ggtatagaac tgagctatgg attaatactc ttgtatctta tcctgttcct aaatatgttg
     6841 gtagaaaaat gaagcagttg ttacgagtgt ctgtattgga aaaaatttta tctatacaat
     6901 tctttaaatg atatgaaggc taggaatgcc aaaacactga catatttcgt ttaaagccta
     6961 tccagtctct tcaattgtat ttgtagaaat gctatcagta atatattcgc gaacactatg
     7021 atttacaaca gtgtggtcgt acatctttgt aactttatta tacaacaacc atttacaggt
     7081 gtaaagttga gcagtgtctt tagtaaattt agggacttgt tttgtcatag ttttgatacc
     7141 tgtattcgtt gtttcatgag catttgacgt ttcttttcat gtaggcattt caacaattag
     7201 aatgatattt ttccgaggat gaacttatat attgtgactt tttagagtta tgatgcctct
     7261 tgatttgact atcgctatca atttcatcca cttttacagt ttcatggttt tatgaaccga
     7321 aacatctagg tacaggtttt agcatcaatt gattgttttt gagccatatg aagttgaaac
     7381 gtggagatgc ttttcttgtg ataacgccct attcaaagag gcataaccgt ttttggagag
     7441 agttcagtac tatgtggcgc taaataatat atgtaaaata gtatggtgta gagatattaa
     7501 acaagattta actaatactt ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg
     7561 tatagatgtt actgacttcg tcagttctat ctacaacctc aaaacagtgt tttgagcagc
     7621 ctgcagctag cttcctagtt tgctctttga ttttcattga gtataaggag aattgtaaaa
     7681 acaaaaatgg ggatttcata taaagtttat tctaggagta tgtatcttga ataaaaattg
     7741 ttatttaagt tctgggggtt atgatgaatg tttttataat aataaaatgc agctagaaga
     7801 aaagttattt taatataaat cactcaacat agcgagaagg cggtttccta tatggaagtc
     7861 gtcttatttt catattgtct aaatacgaga tatttactac aggttatagt tgatttaaac
     7921 aggtctatag atttctaata tattaaggtg aaataatatc ttgtaataca ttgctatgtt
     7981 ctatgaaaaa agcgacgata gctaatgcac aagctcctat acttccacga tgtttgttgt
     8041 aaggtaaaat ttcaatttct atattacgag taaaaggaac gaagtggagc tgatcttgga
     8101 ttttatccct gacttcatga gtgaaaggtt gataattaag caattgactg ttgatataga
     8161 ttttatcagc aggattgatg aggagaagat ttgcaataga agtggccaat aaattgactc
     8221 ctttatcaat ttgttggcgt aaagcggagt cgcctaagtt gtaagctgtt aaaagggtat
     8281 ctaaatgaat gtctttttca gtctttacaa ggctttttag tacagttagt tgggaatttt
     8341 taaataataa ttgggcgtgt ttgattaacc aagcatccga aatatatgtt tgtaaacaac
     8401 ctttttttcc gcattcacaa tattgcccat tcaattcgac aatggtgtgt ccaatttctc
     8461 cgatataagg atttttagag gctcctattt tttcttttgt gaaaaaggaa gtgtaaatac
     8521 ctaatccagc gtgtaggaaa ataaagttat cgggggtatt gtgtggatta aaaaggtatt
     8581 gtcctatagc catacaatcg atattatttt ttacaataaa aggaaaattg aatcttttaa
     8641 ttacatttaa taaattaaaa gattcccata tggggttgtt tgtaatgata cttccggagt
     8701 ctttgttata atgtccaggt attgataagc caaatccaag taattttgtt tccaaaggga
     8761 cgtactctat agctgttttt atcatattgg taatggtgga attgatttct gaaataggat
     8821 aatcttcatt caaaatttct gtctcgaaaa gagttttccc ttgtaagtca catagactga
     8881 gaaagatacc taggacgttt atttcaatac ctccaacaac atacggaata ttatctgtga
     8941 tagaaatagt ttttctacgt cttccagatc cggaaaactc gctaaattca tcaccagttt
     9001 cgtatatgag ggactgttcg cttagctctt ttatgatgtt agtcgttgtt gctggagtaa
     9061 gtcctgtttc attaacaata tctgtacggg atgttgctgg atttcgatat agaaactcca
     9121 gtatagtggc tctattttgt aaaaaggctg attgttttgt aatcatttgt ttcctccttt
     9181 ggtttatttt atattaaaca taagaaaaaa tcaattaaaa ttattattct atacaaagaa
     9241 aaaaatattg taaaaacaac aaaaaatata ttgacaacgc tttctgttag tggtatattt
     9301 aatttataaa aaataaaaaa aggagttccg gtgatgaaca atattttagc gtttttagaa
     9361 acaaaagtcg ctccgtttgg tgaaaaagtt ggcaaccaac ggcatttgaa agctattcgt
     9421 gaaggattta tgatggcaat gcctttgatt ttagtcggct ctttatttct tattctaatc
     9481 agttggcctc aagaggcttt tacaaattgg ctgaatagtg ttggattgct aagtatcttg
     9541 acaactatga atcagtcaac agtagcgatt atctccttgg tcgcttgttt cggtattgcc
     9601 tacaggttgt cggaaggata tggtacagat ggtccgtcgg cagggatcat agccttatcc
     9661 agttttgtat tgatggcacc tcgtttttcg agtatggttt atgataaaaa tggggagcag
     9721 gtcaagcagt tatttggcgg cgcaatacca ttttctagcc tgaatgcatc ttctttgttt
     9781 atggcgatta ctattggatt ggttacagca gagatttatc gtatgtttat ccagcgcgga
     9841 attacgataa aaatgccaag tggtgtccca gatgtagtaa gtaaatcatt ttcagctctt
     9901 ttacctggtt ttactacttt tgttttgtgg gctttggtct taaaaggtct tgaagcggca
     9961 ggagttgcag gaggtctcaa cggactccta ggtgcaattg ttggaacacc gcttaagtta
    10021 attgcaggaa cgcttccagg tatgattcta tgtgttattg taaactcatt cttttggttc
    10081 tgtggagtta atgggggaca agttttaaat gcttttgtag acccagtttg gttacaattt
    10141 actacagaaa accaagaagc tgtggctgca ggacaaacac tccaacacat tattacatta
    10201 ccgtttaaag atttatttgt atttattggt ggcggtggag cgactattgg tcttgcgatt
    10261 tgtctcttcc tatttagtaa gagtcgtgcg aataaaacat taggtaagct agctattata
    10321 ccgtctattt ttaatatcaa tacagctatt ctatttacgt ttccaacagt tttaaatccg
    10381 attatgctga ttccgtttat tgctactcct acaatcaatg ccttgattac ctatgtatca
    10441 atggctgtag gattagtacc ctatacaaca ggtgtaatcc ttccgtggac aatgccaccg
    10501 attataggag gcttccttgc aacaggggct agttggcgag gagctctatt acaagttgtt
    10561 ttgattttgg tttctgtagc aatttattat ccattcttca aaattgcaga taaacgcaat
    10621 cttgaaaaag aaaaagctac tgttggaggg aaataagatg gttatcagag tatttgatca
    10681 acagaaaaat acttattcta gctttgcctt agaggaatta agttactata tgaatcgggt
    10741 ctttaagact aacatagagc ttgtcgagga gaaggaagcg gatatttttg taggattagt
    10801 caataaagag gacagaaaag accatgttct tatctcatta gacaagggta aggggagaat
    10861 tgagtctaat acaattgtag gtttacttat tggaatttac cgaatgtttc atgaatttgg
    10921 ggttgtgtat actagaccag ggcgcagaca tgactttgtt ccagagttac gatttgaaga
    10981 ttttttagat aaacagctat ctatagatga aacagccagt tactatcata ggggagtatg
    11041 tatagaggga gcggattcat ttgaaaatat actagatttc attgattggc tacctaagat
    11101 tgggatgaac agttttttca tccagtttga aaatccttac tcttttttga aacgttggta
    11161 tgaacatgaa tttaatccat atctaaataa agaacaattt tcaaatgaat tagtacaaga
    11221 attgagtgat aggttggata aagaattgca aaaaagaggt cttattcatc atcgtgttgg
    11281 tcatggatgg acaggtgaag ttttaggtta ctcttcaaaa tttggctggg aatcaggtct
    11341 tagtatttca gaggagaaga aaccctatgt cgctgaaata aacgggaaac gagaattgtt
    11401 taatacggct ccgattttaa ccagcctgga tttttcaaat ccagatgtag ctgataagat
    11461 ggtagaaatt atcaaggatt atgccaagaa aagacctgat gttaactact tacatgtatg
    11521 gttgtcggat gctcgtaata atatttgtga atgcgaaaac tgtagacaag aattggtttc
    11581 ggatcagtat attcgtattc tcaatcaatt ggatagggct ttaacgagtg agggattaga
    11641 tacaaagatt tgttttctgc tttatcatga gttgttatgg gcacctcaga aagaaaaatt
    11701 agataatcct gaacgcttta ccatgatgtt tgcaccgatt acaagaacat ttgaaatgag
    11761 ttatgcagat gtagattttg acaattccat acctacgcct aaaccttata tgcgtaataa
    11821 aattatactt ccgaattctc ttgaggaaaa tttatcttat ctttttgagt ggcaaaaagc
    11881 atttaaagga gatagtttcg tatatgacta tcctttaggg cgtgctcatt atggcgattt
    11941 aggctatatg aaaattagtc aaactattta cagagatgta tcttatcttt ccaacctaca
    12001 tttgaacggg tacatttcgt gtcaagaatt acgtgccgga ttccctcata attttcctaa
    12061 ttatgtcatg ggggaaatgc tctggaagaa gacaagaagt tatgaagaat tgattgaaga
    12121 atacttttct gctttgtatg gggaaaattg gcagtctgtt gttgaatatt tagaaaaatt
    12181 atccatttat tcctcttgtg attattttaa tgcaattggc agccgtcaaa gtgatgtttt
    12241 agcgaatcat tattatatag cttacaatct agctgataat tttttaccaa ttattgagga
    12301 aaatatttct aagttattaa atagtcaaaa ggatgaatgg aaacagctca gttatcatcg
    12361 tgaatatgtt gttaagatgg cgaaggcttt atatcttcaa gcaactggaa aaacaaggca
    12421 agctcaagat gaatggagaa atgtgttgaa ttatatccgt gggcacgaat tgctatttca
    12481 atctaatttg gatgtttatc gtgtaattga agtagcaaaa aattacgctg gtttccactt
    12541 ataaatcata agtatagaaa atgaactaag gtattcagag aagattgatc ctaaatatta
    12601 tgaaatttaa ggatttttaa gatatttagg gtcgactttc tatttatatc gtagcgaagt
    12661 cattttaata atgatgtgta aaagatggat caagattgag gaggaagaaa gatgaaatca
    12721 aaagaagaaa taaatatgct tggttttaca attgtcgctt acgcaggaga tgcaaggtca
    12781 gatttgatgg atgctttggc gtttgcgaga gatggatatt ttgaacaggc aagagaattg
    12841 gttgagtctg caaacgactc aatagtgtct gcccatcgag aacagactaa tttattagcg
    12901 gaggaggcat ctggagataa ttttgaagtg agttttatca tgattcatgg tcaagatacc
    12961 ttgatgacaa cgatgctatt gtatgatcag gtcaagtttt ttattgatga atatgaacga
    13021 attcgaaaga ttgaagaaca tattggtttg caatgaggat tagtcatgga aaatttacag
    13081 gttaaagcct taccgaagga gtttttatta ggagctgcta ccgctgctta tcaagtagag
    13141 ggtgcaacta gggtagatgg caaaggaaca aatatgtggg atgtttattt gcaagaaaac
    13201 agtccgttct taccagatcc agctagtgat ttttattatc gttacgaaga ggatataact
    13261 ttggcggcag aacatggttt gcaggctttg cgtttatcta tttcttgggt tcgtatattt
    13321 cctgatatag atggggagcc taatatatta gctgttcgtt attaccatag agtctttcag
    13381 tcttgcttaa aacataatgt gattccgttt gtttctttac atcattttga ttcgcctcag
    13441 aaaatgttag aaacagggga ttggttgaac agagagaata ttgatcgttt catacgatat
    13501 gctcgctttt gtttccaaga atttacagaa gtcaagcatt ggtttacaat caatgaactg
    13561 atgtctcttg ctgcaggtca atatatagga ggtcagtttc ctccaaatca tcattttcaa
    13621 ttatctgaag caattcaagc gaatcataat atgttgttgg cgcatgctct tgcagtcctc
    13681 gaatttcatc aattagggat tgagggaaag gtaggttgta ttcatgcttt aaagccaggc
    13741 tatcctattg atgggcaaaa agaaaatatt ttggcagcta aacggtatga tgtttataat
    13801 aataaatttc tattagatgg aacttttttg ggctactaca gtgaggacac gctttttcac
    13861 ttgaatcaaa tattggaagc taataattct agctttatta ttgaagatgg tgatttagaa
    13921 attatgaaga gagctgcacc tcttaatacg atgtttggga tgaattatta tcgttcagaa
    13981 tttattcgtg aatacaaagg tgaaaataga caagaattta attcaacagg aataaaagga
    14041 cagtcttctt ttaaattaaa tgctctaggt gaatttgtaa aaaaacctgg tattccgaca
    14101 acagattggg attggaatat ttatcctcaa gggttatttg atatgttgct tcgtatcaaa
    14161 gaagaatatc ctcaacatcc ggtcatttat ttaactgaaa atggtacagc ccttaaagaa
    14221 gttaagccag agggcgagaa tgatattatt gatgacagta agagaatccg ttatattgag
    14281 caacatttac acaaagtttt agaggctcga gatagaggag tcaatattca aggctatttt
    14341 atatggtctt tgcaagatca attttcttgg gcgaatggct acaataagcg atatggtctt
    14401 ttctttgttg attatgaaac acagaagaga tatattaaga aaagtgctct ttgggtaaaa
    14461 gggctaaaac ggaattaagg ttagcgattt gactgatgtt taatatgttt taaatatgag
    14521 gttgaatttt ttataggagg agttttatgg ataagctagt cgctgccatt gaaaagcaac
    14581 aagggaaatt tgaaaaaatt tctactaata actatatgat ggctattaaa gatggattca
    14641 ttgctactat gcctttaatt atgttttcaa gctttttgat gattattatt atgattccta
    14701 aaaatttcgg agtagagtta ccgagtccag ctattgtctg gatgagaaaa gtgtatatgt
    14761 taaccatggg agttttgggt attattgttt cagggactgt tggaaagtca ttagttggaa
    14821 atgttaacag aaaaatgcct cacggaaagg taataaatga tatttctgca atgttggcag
    14881 ccatatgtag ttatctggta ttaactgtaa cgcttgtagt tgatgagaag acgggatcta
    14941 caagtttgtc gacaaactat ttaggatctc aaggattgat aacttcgttt gtcagtgcct
    15001 ttattactgt aaatgtttac cgattctgta ttaagcgaga cattactatt catttaccta
    15061 aggaagttcc tggggctata tcacaagctt ttagagatat tttccctttt tcttttgttt
    15121 tacttattag tggtttgtta gatattgtat ctcggtttag tttagatgtt ccttttgccc
    15181 aagtatttca acaactattg actcctattt ttaagggggc agaatcatat cctgctatga
    15241 tgttgatttg gtttatgtgt gctttgcttt ggtttgttgg aattcatgga ccatctattg
    15301 tcttacctgc tgttacagct ttgcaactga gcaatatgga agagaatgct caacttcttg
    15361 caaatgggca gttcccttat cattctttaa cacctaattt cgggaattat atcgctgcta
    15421 ttggaggaac gggggctacc tttgttgtac catttatttt gattttcttt atgcggtcta
    15481 aacaattaaa atcggtaggt aaagctacaa ttactcctgt tttatttgcg gtaaatgaac
    15541 ctcttctatt tggtatgcct gttattttga atccctatct ttttgtccct tttttgatga
    15601 ctccaccagt gaatgtattt ctaggaaagg tatttattga tttctttgga atgaatggat
    15661 tttatatcca gttaccttgg acctttcctg gtcccttggg attgttaatt ggaacgaatt
    15721 ttcaacttat ctcctttgta tttttatctt tgattttagt tgtcgacata ttgatttatt
    15781 tgccattctg tagagcgtat gatagacagt tactggtgaa agaagatatt gcaagctcaa
    15841 atgatattat tttagaggag gatacaagtg aaataattcc tggtgagata gatgaaataa
    15901 aaagtaagga gttgaaagta ctggttcttt gtgcagggtc tggaacaagt gcgcaattag
    15961 ccaatgcaat taacgagggg gctaacttaa cagaggttag agtgattgcg aattcaggag
    16021 cgtacggagc tcattatgat attatgggtg tttatgattt aattattctg gctccacaag
    16081 ttcggagtta ttatagagag atgaaggtgg atgcagaaag attaggtatt cagatagttg
    16141 ctaccagagg aatggaatat attcatttaa caaagaatcc aagtaaagcc ttacaatttg
    16201 tattggagca ttaccaagct gtgtagtaag tttttccatc ttttatttga gtaagaactt
    16261 tgcttacaga caggcttgga tttaaaaacg ttcccccttt ttaatataaa aatccctctt
    16321 tcacaattgt aaaaagaggg attttgtatt ttatctctta gaccaagttc tcttcataaa
    16381 gagaagtagg attgggtaaa tctccaagcg gcctgcaatc attgtaaagg agaggagaat
    16441 ttttgagata ggactaaaga ttgagaaact agaagtggtt cctagaatag gcccgatatt
    16501 attgaaacag ctaaagacag cgctggtcac gaccagaaaa tcattgctat ctaggctgac
    16561 aataaagata agcgctagca aaatcatagc atagatgaca aagtacttga gaatcttatg
    16621 ctgggtatct ttatcaatca ccgtttgatt cacatggagg gtcaaaacac ggtggggcga
    16681 taggattgac aaaatttggt ttttggcaat ttttgaaagg atgaggcctc gaataatctt
    16741 gagtccacct gcagttgatc cagcagagcc accgattgcc atgaggaaaa ggaggataaa
    16801 ctgagagaag aggggccagt tggtaatatc tccatatcca aaaccagttg ttgtaatgat
    16861 gttggaaacc tggaagaagg tcatttcaaa gctctttgaa aaccctgggt agaggtagag
    16921 ggtgttgagg ctaatcaagc ctgtagaaac cagtacaatg accaagtaag cccgaagttc
    16981 ttcgtcacca aagaaggcct tgatgcgacg gagcatgagg tagtagtaga ggttgaaatt
    17041 taccccaaaa accagaactc cgatactgac cagataggta atcagtgagc tgccatagtg
    17101 ggcaattccg tcgttataga cggtaaagcc tccagttccc gctgtcccca tagcaatgac
    17161 aaaactatcg tagagaggca taccagctag ataatagatg atgacaaaga gggagaagag
    17221 agctagataa aggagataga gaatctgggc agtgtttttt agtttggata caaccttgcc
    17281 aaaaacagga cctggaacct cagccttcat cacctctagg tggctatttt tggcattgtc
    17341 cataatagca agtgcaaaaa caagcactcc catccctcca atcaagtggg taaaacttcg
    17401 ccagaagagg agggaacggc tgagaaccga aacgtcgttc aaaatacttg ctccagtagt
    17461 tgtaaaccca gaactaattt caaaaaaggc atcaataagg ctggggattt gcccagaaaa
    17521 gacaaagggg agaccaccaa agaaagacca aaggatccaa cagagggcaa cgatcaagac
    17581 tccctccttg gcataaatcc gttgattttt tggcttctgt aaactccctg aaccgcctaa
    17641 caatacgaga atccctatgg tcgaaaagag ggctgtaaag acttggctcg attcacggta
    17701 atagacagcg atagccacag gaaccaagag gagaacagct tcaatcaaaa gtaactttga
    17761 aaggaggtaa cgaatcatac ttttattcat ttcttacctc gcaatcaagt cataaatctt
    17821 ggtgatgttt ggcaacaagg ttgttactag gagcttgtct ccaacttcca acatatcctc
    17881 cccagttggg aaaatagtct tgccctttcg aataatggct gcaataagaa cccctttttt
    17941 caatttcagt tgagaaagag gtttggcagt cattttattg gcttccttga tatggaattg
    18001 cagggtttcg atttggccat tggctagatg gtgcatggct tgaaggtctg aatactgggc
    18061 attaactcga ccacgaataa agtgcataat cgtatctaca gcgatgcttt taggtgtgat
    18121 gatacttgaa aaatcaggcg cattgataat ctcgaggaga ctggtacgat tgaccttagt
    18181 aatatttttc tgtacaccta ccctgtcaag gaacatagat gtaatcagat tttcctcatc
    18241 gacacctgtt agagtcgcaa cggcatcata gtgttgagca ctttcttcca gcaggatatc
    18301 ttttgcggtt ccatctcctt gaacgatgta gagatttggg aatttctcgc taaagaagct
    18361 ggcgatttca ggattgattt caatgacttt tgtatcgata cgactatctt tgagaatacc
    18421 aagtagataa taggcaattc tacctgcccc aacgatgaga aggctcttca cggcgcgtga
    18481 tttaaaataa ttatggaaga gtatcatatc gacacggtta ccagtgacaa agattctatc
    18541 tttatcctgt acagtcatgt caccgcttgg aatgataatt tgatgctccc tctctatcgc
    18601 acagacaatg acattaccaa attttttacg aaaatcagaa atgggcattt ggcaaagacc
    18661 gctggtggac ttgacgacaa attccatgag gctaacgcgt ccaccagcaa agcgttcgac
    18721 agacagggcg ttggggaagt caatgatatt cgcgatagcg cgggcagcca agagctcagg
    18781 attaacgata agagaaaaac cgagaatatt cttttccttg aaataagagt tagaatattc
    18841 agggttccgc acccgaacga tagtttcttt agctcccatt ttcttggcta gaactgctgc
    18901 aatcatgttg acttcatcgt gctcagtcag ggcgataaag atatcacaat cttggacgct
    18961 ggcttgctca agaatggcaa aatcggcccc gttaccaagg ataccaatga tatcaaagcg
    19021 actgacaata tgattgagaa cagcttcgtc ttgctcaatc agcaaaacat catgcttttc
    19081 tgcaaccaag gagcgacaga gggcaaaacc aacttttccc cctccgacaa ggataatttt
    19141 cataataaaa cctacttttt catgatgtaa ctatcatacc ctttttcaag aaaaaatgca
    19201 cctactagct aataaccaga gtttttagta ggaaatttgc tataagttaa aactataccc
    19261 taaccaattg aaatagctat tagcgacttt ctctgaaata tggtatgata aaggatatac
    19321 aaggagataa aatgaataat aatttactgg tattacaatc agactttggt ctggttgatg
    19381 gtgcggtatc ggctatgatt ggagtggctt tagaagagtc tccaacctta aaaatccatc
    19441 acttgacgca cgatatcacg ccttataata tttttgaggg gagctatcgt ctctttcaga
    19501 cggtggatta ctggcctgag ggaacgacgt ttgtatcggt tgtcgatcca ggtgtcggtt
    19561 cgaaacgtaa gagtgtagtt gccaagactg caaaaaatca atacattgtc acgccagata
    19621 atgggacgct ttcctttatc aagaaacacg ttggcattgt agccattcgt gagatttctg
    19681 aggtggccaa taggcgtcaa aacacagagc attcttatac cttccacggt cgtgatgtct
    19741 atgcttatac tggtgctaaa ctggccagtg gtcacattac ttttgaggaa gtagggccag
    19801 agctcagtgt ggaacagatt gtagagcttc cagtcgtagc gaccatcata gaagatcatc
    19861 tggtgaaggg agccattgat attctggatg tgcgtttcgg ttcgctttgg acctctatca
    19921 cacgggaaga attttacaag ctggaaccag aatttggtga tcgttttgaa gtgaccatct
    19981 atcatgctga tatgctggtc tatcaaaatc aggttgtcta tggcaaatca tttgcagatg
    20041 tgagaattgg gcaacccatc ctttacatca actctctcta tcgtttaggt ttggctatca
    20101 accaaggttc ctttgccaag gcctataatg taggtgtcgg ttcatcttgg accattgaaa
    20161 taaagaaaat agaaggataa aataggagaa tagtatggaa atcaaattta caattaaaca
    20221 agttgttgct gtcggaattg gcgctgccct ctttgtcgtc atcgggatga tcaacattcc
    20281 aacccctgtt ccaaatacaa gcatccagct tcagtatgcg gtacaagcgc tactttctat
    20341 tatttttgga ccgattatcg gtttgcttgt cgggttgatt ggtcatgcaa tcaaggactc
    20401 tcttgttggt tatggtctat ggtggacttg gattatcgct agcggactct ttggcttagt
    20461 tgtgggactt tttagaaagt acgttcgcgt gatcaatagt gtttttgact ggaaagatat
    20521 tcttattttt aatctcattc aactacttgc aaatgccctt gtttggggtg tcttggcacc
    20581 acttggagat gttgtgattt atcaagaagc ggcagaaaaa gtatttgcac aagggattgt
    20641 tgcgggaatt gccaatggtg tatctgtagc tattgcagga actcttctct tacttgccta
    20701 tgcaggaacc caaactcgtg caggaagttt gaaaaaggac taatactcaa tgaaaatcaa
    20761 agagaaaact aggaagcaag tcgcaggttg ctcaaaacat ggttttgagg ttgtagatga
    20821 aactgacgaa gtcagtaacc atacctacgg caaggcgaag ctgacgtggt ttgaagagat
    20881 tttcgaagag tataaaatga tggggaaggc tgggcaacta gtctttttcg atgtttatag
    20941 attagttagg caagtaagct aggataggaa tctttttggc gctaagattt taagaggaga
    21001 gactgcaaga agggcttgat ttatgataaa atagaagtct aagaagcgaa tgaagagagt
    21061 aagatgaaag aagctataat tgagtggaag gatttctctt tccggtatga aacacaacaa
    21121 gaaccgacct tgcaagggat agacttgacc atttacaagg gagagaaagt cttaattgtt
    21181 ggaccatctg ggtcaggtaa atctaccttg ggtcagtgtt tgaatgggat tattcccaat
    21241 atttacaagg gtcagacata tggagaattt ttgataaagg gtcaagtagc ctttgatatg
    21301 agcatctatg ataagtctca tctggttagc acagttttac aggatacaga tgggcagttt
    21361 attggcttgt ctgtggcaga agatttggcg tttgctctgg aaaatgatgt gacagcccta
    21421 gatgagatga aaggtcgtgt ttataaatgg gctgaaaagc tggaccttct tcctttactg
    21481 gatcagcgtc ctcaggattt gtcaggtgga caaaagcagc gagtcagtct ggctggtgtc
    21541 ttgattgatg aaagtccgat tctcttgttt gatgagccac tcgccaatct agatcccaag
    21601 tcaggtcagg atattatcga attgattgac cagattcata aggaagaggg gacgacgact
    21661 ctgattatcg agcaccgttt ggaggacgtt ctgcatcgcc ctgtggatcg gattgtcttg
    21721 ataaacgatg gtcgtatcct ttttaatggg agccctgacc agttgcttgc gactgattta
    21781 ttgactcaaa atggaattcg agaacccctt tatctaacga ctctccgtca attaggtgtg
    21841 gacttagtca aggaagaaca attagcagat ctggataact tgtctatctc aaaagggcaa
    21901 atccagttac agacggaact ggtaaaagaa accccagcat tgcagtcact ctttatacta
    21961 gaggaagtat ctttttctta taatgataga ccgattttaa aatccctaca tttagatatt
    22021 aaaaagggtg aaaagattgc tattgtcgga aaaaatggag cagggaaatc aactctagcc
    22081 aaggctataa gtagctttat tcagacggaa ggacgctatc tttgggaaaa acaggatata
    22141 aaaggcgatt ctgttgcaga gcgggcggaa cgagtaggct atgtgctaca aaatcctaat
    22201 caaatgattt caaccaatat gatttttgat gaggtggctc tagggctccg tttgcgaggt
    22261 gtgaatgaga aggaaattga aacgagagtc tatgaaacct tgaaaatctg tggactttat
    22321 gaattccgta attggcctat ttctgccctg tcatttggtc agaaaaaacg tgtcaccatt
    22381 gcttcaattt tggtcttagg agctgaaatt attctcctag atgaaccgac tgcaggtcaa
    22441 gatcagaaga actatactga gattatggaa tttctcgaag agttacatca aaaagggcat
    22501 accattgtca tgattaccca tgatatgcaa ttgatgctgg attattcaga ccgggtcctt
    22561 gtcatggtgg atggagaatt gattgccgat actgttccag ccagtctgtt gagcgatcct
    22621 gagctgttag taaaagccaa tctaaaagaa acctccatct ttaacttggc taagaaacta
    22681 gatgtggatc cactggattt aacggcattt tacaaagaaa ggagagaggg atgcaagcta
    22741 aattaatcgg ttaccagcat agagatactg tgattcatcg cttgtcagga gctgggaaac
    22801 ttctcttttt cattctggta tcattggcgg ccatgattag ctatgatacc agaatgctct
    22861 tgctgattgc catcttttca gtctttctcc tctatttatc agaaatccgc tttaaagatg
    22921 tctcctttgt agccgttttt gcgacggtat ttgccgtttt aaacgttttg atggtctatc
    22981 tcttttctcc cgagtatggg gttggacttt atggagagag aagtgtgatt tggcagggaa
    23041 tcggtgtcta cactctaacc agccaggagc tcttttatct gctaaatttg gccattaagt
    23101 atctttgcac cattcctctg gctattatct ttttgatgac aacccatcct agtcagtttg
    23161 cttccagttt aaatcaaatt ggtgtgccct ataagattgc ttattctgtc agcctgacct
    23221 tgcgctatat tccagatttg caggaagaat tctttactat caagatgtct caggaggcgc
    23281 gtgggatgga attatccaag aaagcttctc ttatgcaacg aatcaaaggc aatctgctca
    23341 ttattacgcc cttgattttt agctcgctag aacgcattga taccattgcg actgccatgg
    23401 agcttcgccg ctttgggaaa gagaaaaaac gcacatggta tagttatcag gccttgaaaa
    23461 aaggagacta tattaccttg ctcttggcaa ccttgttttt agtagttagt ttactactta
    23521 tcttgcagaa tcagggacga ttttacaacc cttggaaata gcttgaaaaa attgaaaaaa
    23581 tcaagtcatt tctattgaca atgattctga aagtgttata ctaagaaagt agtttcgctg
    23641 atttacttca aacctgttgt gaggtaagtt aacgatgcct taaccacgct gtttgctgag
    23701 cttgactccg ggcagtgtgg ctattttttt gcaatggtga aaggaagcaa gtcatgacaa
    23761 atcacattgt attatttgaa cctcaaattc cacaaaatac aggcaatatc gcgcgtactt
    23821 gcgctgcgac caattctccc ctccacatca tcaagcctat gggctttcct attgatgacc
    23881 gcaagatgaa gcgggctgga ttggattact gggataagct agagatttat ttttacgaga
    23941 gtttagaaga tttcatatct cagatgaagg gaaaactcta tctgatttcg aaattcgcgg
    24001 aaaaaatcta ttctgaggtg gatttatcga ctgacgagga ccattatttt ctctttggac
    24061 gtgaagacaa gggcttacct gaagatttta tgcgagaaca tcctgataag gctctccgta
    24121 ttcccatgaa tgatgaacat gtccgcagtc tcaatgtgtc taataccgtc tgcatgattg
    24181 tctatgaggc tcttcgccag cagaactttg caggtcttga gctcgtccat acctatgaag
    24241 tggataaatt gaaataaaaa atgaaaatga acaaaatgct tgcgcttgca agcgtttttt
    24301 gttatgataa aagagtcttc agggcagggt gtgattcccg accggcggtg actttaacta
    24361 ggaaatgatc ttttcctttt atactttgtt gacaagcttt gcctaaccag aagttatgcc
    24421 tacagcttgt cgcctagtct aaaagaaaaa tctctatttc tttctcttta aagaagtccg
    24481 cgagcgcaag ctgatgtggt gagattccac aaccgacagt atagtctgga tgggagaaga
    24541 cgaaagaata gctttgtctg ttttgataga tttatagccg gattgtaacc acttgctttg
    24601 tttttcttta atagagtaag agggaacttt tgggatataa aaagtgagaa tagatagagg
    24661 aatcctttcc aacttcttct gattttatag aaaattggag gaacctgtta tgacaaacac
    24721 acgtcgactt tcgaccattg caattctatc agccatctca tttgtgctga tgtactttga
    24781 ctttccgctt ttaccagcgg catctttcct caagatcgaa tttagtatct taccagtcct
    24841 tgtgggtctg gtggtcatgg atttgcctgc tgctctagga gtgctcttgc ttcgctcact
    24901 cttgaaattg cttcttaaca gccaaggagt gaatacttac attggtttgc cgatgaatat
    24961 cgtagctttg ggagtttttg tcatcgtatt tgctttgatt tggaaaaagg aacggacacc
    25021 ccttcgtttc ctactaggct ctctagctgg aactattggt ttaaccttgg ccatgttggt
    25081 tctcaactat gtttatgctg ttcctttgta cgctaagttt gctaactttg atattggaaa
    25141 aattttggga ctttccaact acctaatgac catggtatta ccttttaact tgattgaggg
    25201 tgtaatcttt tccgtttcat tctggttgtt gtacgtcctt ttgaaaccaa ccttaaaaca
    25261 ctatgaaaga taaacaaaca tttttaatga agggcagttt tgccctttta cttttcgtta
    25321 ttcttggcta catggtcaaa ttttaccctg aaacgctggt cggttttgac caatcgattc
    25381 agactgccat tcgaggagac ttaccagatt atttgactat tctttttcga tccctcacac
    25441 gtctgattga tatcccagtg attatcactt gggttgtcat tacagctttt gtcttttatc
    25501 gtaagcgatg gaagatagaa agtttcttca tgctgggaaa tctggctttg gcaggtcttt
    25561 taatcgtgac ctttaaaaat atctaccagc gcccacgacc agctatctta catctggtgg
    25621 aagagaaggg attttccttc ccaagtggtc attctctggc tgtaactttg atggtaggta
    25681 ctctgattgt cattctcagt caacgaatta aaaatccagt ctggagaaaa atcgtacaaa
    25741 tcgtccttgg cctctaccta gtcagtgtgc tggtatcaag agtctatctg ggagttcatt
    25801 acccatcaga cgtccttgcc agtctctgtg tgggcttggg agtcctgttt atcgagtttc
    25861 ccttctatga caagctccgc ttccaatggc gatttaaagg caaacagaag tgagtatcga
    25921 attcccttga ggagaaagaa atgaaagtca atatagcaga tcttcatccg actcaactat
    25981 atttatcaga aaagaagttg caagatattc agatgcttta ccagtcggca gaaacaatcc
    26041 aagtcgatcc aatcagtatt cttgcctttg gagattgttt gctgattaca gatgggcatc
    26101 acagggctta tcaggcttta ttggcaggtc gggatacgat ttctgctgag tgggatagag
    26161 atggtggtga tgaactatat catctctatg cgcaagcttg cgaggaaaga aagatttact
    26221 ctgtttttga tttagaagat cgtatcctag ctcaagatgg gtatgaagca aaatggtata
    26281 actggtgtga tggttttaat caagcagcaa ctcttttgtt gaaaaggtag tgcattgtgt
    26341 tttgttcctt attataaggt caatcattgt gaggaagctt ttgcttggta tcaggatgtg
    26401 aacttggttt acctcgtaga tggggtgaag cttccttaca gtcaagcgac cttggaagcc
    26461 atgtattcct atttggatcg gcatggtgag cttttttgga ttgaagtcaa ggagaaggga
    26521 gaatggtttc caattgggga tattacacta tctcaggata atctccccat tgtgattggg
    26581 aattccgctt accaacatcg aggacttgga aaaaagattc taagtgcttt gattgaattg
    26641 gctcgagtaa aaggatggaa agaattgaga gtcaaggaaa tctacaccta caatcatgct
    26701 tctaggaggt gtttcaagtc gcttggattt gtggaaaatg gagcaacaga aaaaggaatg
    26761 agttttatat tggaattagt ctaatcctgc cattttctcc cccttaacct ttgactattc
    26821 tgcaaaatta tcgtaaaata aagagtaaat gataaaatga ggtcagagtc tgttcgctct
    26881 ggcgatagta gtataaatga ggagaaacgc tttggaatta gaagtatttg ctgggcaaga
    26941 aaaaagtgaa ctatctatga ttgaggtagc gcgtgctatc ttggaacttc gtggtcgcga
    27001 tcatgagatg cattttagcg atcttgtaaa cgaaattcaa aactaccttg gaacatcaaa
    27061 cagcgatatc cgcgaagctt tgcctttgtt ctacacagag ttgaactttg acggtagctt
    27121 catctcactt ggggacaaca aatggggtct tcgttcatgg tatggtgtgg acgaaatcga
    27181 cgaagaaatc atcgctcttg aagaaaatga cgacgatgaa gtagcaccaa aagctaagaa
    27241 aaaacgtgtt aatgccttta tggatggtga ttcagatgcc attgactaca atgcagatga
    27301 tccagaagac gaagatgcat acgaagcaga tccagctctt tcatacgatg atgaaaatcc
    27361 agatgatgaa aaaaatgaag tggaagctta tgatgcagaa atcaacgaaa tcgctccaga
    27421 tgacttggga gaagatgtgg atctcaacga agacgacgac gagttttcag atgacgacgc
    27481 tgaaaccagc gaggaataag agttagctat tgacaattat cctattttta ggtatcatat
    27541 tgtttgggca cctcttttag aggtcggggc tccctagttc ttagggagct atttttgttt
    27601 tttcaagaag ttatcttctt gtattttata ctcaatgaaa atcaaagagc aagctaggaa
    27661 actagccgta ggctgctcaa aacactgttt tgaggttgta gataagactg acaaagtcag
    27721 gaacacatat ctacggcaag gcgacgttga cgcggtttga agagattttc gaagagtatt
    27781 agttgtgaat ctggtgcagt cgtcccagat tattcttatt agtagggtct tgttttctat
    27841 atcccctcgt agttaacaag accttgagca ttttagaaag aggaatctat gtctacgaaa
    27901 tatatttttg taactggtgg tgtggtatcg tccattggga aagggattgt ggcagcgagt
    27961 ctaggccgtc tcttgaaaaa tcgtggtctc aaagtaacca ttcaaaagtt tgacccttat
    28021 atcaatattg atccgggaac catgagtcct taccagcacg gggaagtttt tgtgacagat
    28081 gacggagctg agacagattt ggacttgggt cactatgaac gtttcatcga tattaatctc
    28141 aacaaatatt ccaacgtgac aactgggaaa atttacagtg aagttcttcg taaagaacgc
    28201 cgtggagaat accttggggc aactgttcaa gtcattcctc atatcacaga tgctttgaaa
    28261 gaaaaaatca agcgtgccgc tctaacgacc gactctgatg tcattatcac agaggttggt
    28321 ggaacagtag gagatatcga gtccttgcca ttcctagagg ctcttcgtca gatgaaggca
    28381 gatgtgggtg cggataatgt catgtatatc catacaacct tgcttcctta cctcaaggct
    28441 gctggtgaaa tgaaaaccaa accaacccaa cactctgtca aagaattgcg tggcttggga
    28501 atccaaccaa atatgttggt tattcgtaca gaagagccag ctggtcaagg aattaaaaat
    28561 aaactggccc agttctgtga tgtggcacca gaagccgtta tcgaatcgtt ggatgttgaa
    28621 cacctttacc aaattccact gaacttgcag gcacaaggga tggaccaaat tgtttgtgat
    28681 catttgaaat tagacgcacc agcagcggct atgacagaat ggtcagccat ggtggataag
    28741 gtcatgaacc tcaagaaaca agttaagatt tcccttgttg gtaagtatgt ggagttgcaa
    28801 gatgcctata tctcagtggt cgaagccttg aaacactctg gctatgtcaa tgatgcagaa
    28861 gttaaaatca attgggtcaa tgccaatgat gtgacagcag agaatgtagc agaactcttg
    28921 tctgatgcag acgggatcat cgtaccaggt ggttttggtc aacgtggtac agaagggaaa
    28981 atccaagcca tccgctatgc gcgtgaaaat gatgttccaa tgttgggagt ctgcttggga
    29041 atgcagttga catgtatcga gtttgctcgt cacgttttag gtcttgaagg tgccaattct
    29101 gcagagcttg caccagaaac aaaataccct atcattgata tcatgcgtga tcagattgat
    29161 attgaggata tgggtggaac ccttcgtttg ggactttatc cgtctaagtt gaaacgtggc
    29221 tctaaggctg ctgctgctta tcacaatcaa gaagtggtgc aacgccgtca ccgtcaccgt
    29281 tatgagttta ataatgcctt ccgtgagcag tttgaggcag caggttttgt cttttcagga
    29341 gtttctccag acaatcgttt ggtagaaatc gtggaaattc ctgaaaataa attctttgta
    29401 gcttgtcagt atcaccctga actgtcaagc cgtccaaacc gaccagaaga actctacact
    29461 gcctttgtta ctgcagcggt tgagaacagc aattagcaaa atcagaacct ttgagaaaaa
    29521 tctcagaggt tttttgcata cgatgatatt gcagtatatc tgaggtaggg gtcctctgta
    29581 tgtacctgct accgttgaaa tcaataggga ctccctcttg ccctgtgcta gtgaatggat
    29641 ttatcagtat attgaaatga aataaaattt gaacaaatta attcggaaag ccaaatcaat
    29701 ttctagcaaa gttttaggaa ctggattgta tagtgaattg aaataagatg tgaa
//
LOCUS       DAVHSH010000020        26597 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000020 DAVHSH010000000
VERSION     DAVHSH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.020"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..210)
                     /locus_tag="VVR08_001050"
     CDS             complement(<1..210)
                     /locus_tag="VVR08_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6074982.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMP"
     gene            403..900
                     /locus_tag="VVR08_001051"
     CDS             403..900
                     /locus_tag="VVR08_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU6074983.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            900..2555
                     /gene="dnaX"
                     /locus_tag="VVR08_001052"
     CDS             900..2555
                     /gene="dnaX"
                     /locus_tag="VVR08_001052"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU6074984.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2583..2777
                     /locus_tag="VVR08_001053"
     CDS             2583..2777
                     /locus_tag="VVR08_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU6074985.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2927..3697
                     /gene="sufC"
                     /locus_tag="VVR08_001054"
     CDS             2927..3697
                     /gene="sufC"
                     /locus_tag="VVR08_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU6074986.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3725..4987
                     /gene="sufD"
                     /locus_tag="VVR08_001055"
     CDS             3725..4987
                     /gene="sufD"
                     /locus_tag="VVR08_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU6074987.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4998..6224
                     /locus_tag="VVR08_001056"
     CDS             4998..6224
                     /locus_tag="VVR08_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6074988.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPALARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6211..6651
                     /locus_tag="VVR08_001057"
     CDS             6211..6651
                     /locus_tag="VVR08_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU6074989.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAGQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDVVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6705..8117
                     /gene="sufB"
                     /locus_tag="VVR08_001058"
     CDS             6705..8117
                     /gene="sufB"
                     /locus_tag="VVR08_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU6074990.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8348..9589)
                     /locus_tag="VVR08_001059"
     CDS             complement(8348..9589)
                     /locus_tag="VVR08_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU6074991.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9692..10801
                     /locus_tag="VVR08_001060"
     CDS             9692..10801
                     /locus_tag="VVR08_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6074992.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11447..11794
                     /gene="ssrA"
                     /locus_tag="VVR08_001061"
     tmRNA           11447..11794
                     /gene="ssrA"
                     /locus_tag="VVR08_001061"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11977..12064)
                     /locus_tag="VVR08_001062"
     tRNA            complement(11977..12064)
                     /locus_tag="VVR08_001062"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12028..12030),aa:Ser,seq:gga)
     gene            12226..12966
                     /locus_tag="VVR08_001063"
     CDS             12226..12966
                     /locus_tag="VVR08_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6074993.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPAVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRSILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12963..13874
                     /gene="pfkB"
                     /locus_tag="VVR08_001064"
     CDS             12963..13874
                     /gene="pfkB"
                     /locus_tag="VVR08_001064"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU6074994.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13871..15823
                     /locus_tag="VVR08_001065"
     CDS             13871..15823
                     /locus_tag="VVR08_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6074995.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15987..18212
                     /locus_tag="VVR08_001066"
     CDS             15987..18212
                     /locus_tag="VVR08_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6074996.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18257..18685)
                     /locus_tag="VVR08_001067"
     CDS             complement(18257..18685)
                     /locus_tag="VVR08_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6074997.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18823..19965
                     /locus_tag="VVR08_001068"
     CDS             18823..19965
                     /locus_tag="VVR08_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6074998.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDGVQALTKIPTEKYLTERVDFATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NHPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19974..21188
                     /gene="thiI"
                     /locus_tag="VVR08_001069"
     CDS             19974..21188
                     /gene="thiI"
                     /locus_tag="VVR08_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU6074999.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21323..22136
                     /locus_tag="VVR08_001070"
                     /pseudo
     CDS             21323..22136
                     /locus_tag="VVR08_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            22158..22493
                     /locus_tag="VVR08_001071"
     CDS             22158..22493
                     /locus_tag="VVR08_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEU6075000.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSWMA"
     gene            22490..22897
                     /locus_tag="VVR08_001072"
     CDS             22490..22897
                     /locus_tag="VVR08_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6075001.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            22910..24076
                     /locus_tag="VVR08_001073"
     CDS             22910..24076
                     /locus_tag="VVR08_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6075002.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            24584..26077
                     /locus_tag="VVR08_001074"
     CDS             24584..26077
                     /locus_tag="VVR08_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6075003.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFRGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            26090..>26597
                     /locus_tag="VVR08_001075"
     CDS             26090..>26597
                     /locus_tag="VVR08_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6075004.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNEL"
BASE COUNT         7907 a         4883 c         5841 g         7966 t
ORIGIN      
        1 aggcatacca gttgtttcga ggtaagggat cttagacggt ttttgaaagt catatttctt
       61 cattagactt ccacaatcag ggcaagatgg agcctcataa tccagcttag cgataatttc
      121 tttgtgggta tccatattga tgatatctag aatcttgatg tttgggtctt taatatcgag
      181 cagttttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttggtcgc
      241 ttttcattat aggtcatatg ggactttttt tctacacaaa ataggctcca taatatccat
      301 aggggattta cccactacaa atattataga gcccaaaatc ctttgtttac taaacaaggg
      361 atttttcttt tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa
      421 caatcacgtt atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat
      481 gttttggcta atctttccaa cgccagtgct ctcataaaat cacgttttcc taataccgta
      541 tttgcaggct tttatttgtt cgatggaaag gaattggttt taggcccctt ccaaggaggt
      601 gtttcctgca tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag
      661 gaaactgtta ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta
      721 gctaaaagtg aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat
      781 ctggattctt cagagattga ggattacgat gctatggatc gagattattt ggaacaattt
      841 gtcgctattt tgcttgaaaa gacaacatgg gactttacga tgtttgagga aaaatcttaa
      901 tgtatcaagc actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag
      961 aagttgtggc taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc
     1021 ttttttctgg tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta
     1081 tgaactgtcc caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag
     1141 tgacggacgg tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag
     1201 atgaaattcg cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg
     1261 tttatatcat agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga
     1321 cgctggaaga accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga
     1381 ttcctgctac tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg
     1441 atattaagga acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg
     1501 ctgtggaaat cattgccaga cgggcggaag gtggaatgcg ggacgccttg tctattttgg
     1561 atcaagccct gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta
     1621 ctggcaccat tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg
     1681 ttcccaaagc tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt
     1741 ttgtgaccga tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa
     1801 atactcatca tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg
     1861 aaatgattcg cttagcaaca gtgagtttag cagatattaa gtctagtttg cagcccaaga
     1921 tttatgctga aatgatgacc gtccgtttgg cggaaatcaa gcccgaacca gctctatcag
     1981 gagcggttga aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc
     2041 tttctaatgt aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg
     2101 gcaaaacagt ctatcgtgtc gatcgcaata aagtgcaatc tatcttacaa gaggccgtcg
     2161 aaaatcctga tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa
     2221 ttgaaagtct aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca
     2281 atgaacacca tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac
     2341 gagacaatct caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg
     2401 agattttagc tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag
     2461 ccaaatcttc tcaaactgaa aaggaagtag aagaaagcct gattccagaa ggatttgaat
     2521 ttttggctga taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt
     2581 ttatgaataa acaacaattt attattatgg cgctgtttac agctgctgag acctattttt
     2641 tcaatgaagc ctggatgact ggccgctata ttatggcagc cttttgggca attttactct
     2701 ttagaaattt ccgagtcagt tatgtgatgg gcaaaatcgt tgatgtcatc gatcagcatt
     2761 ttaataggaa agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt
     2821 tgttatacta gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt
     2881 ttttctagta agtactgtaa aagttttgaa aaagaaagga actatcatgt cagtattaga
     2941 gatcaaagat cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac
     3001 cctgaaaaca ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct
     3061 ttctgccgct atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga
     3121 tggcgtaaac atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc
     3181 tatgcaatac ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat
     3241 gaatgcgggt aaagaagatg atgagaagat ttcagttcgt gagtttatta ctaagctaga
     3301 tgaaaaaatg gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg
     3361 cttctctggt ggtgagaaaa aacgcaatga aattcttcaa cttttgatgt tggagccaac
     3421 atttgctctt ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc
     3481 taaaggtgtc aatgccatgc gtggtgaagg ttttggtgct atgatcatca ctcactacca
     3541 acgtcttttg aactatatca cacctgatgt ggtacacgtg atgatggaag gtcgtgttgt
     3601 cctttctggt ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaattagc
     3661 tgaagaactt ggctacgact acaaggaaga attgtaattt cctcgtatct tttaggagaa
     3721 gtaaatgact agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt
     3781 ggctgatctc cgtcaaaaag cttttgacaa gattgagact ttggaattac cagttattga
     3841 gcgtgtcaaa ttccaccgtt ggaatctggg tgatggaacg attacagaaa atgagccatc
     3901 agcaaatgtt ccagatttca cagctttaga tcatcacttg aagttggtgc aagtaggaac
     3961 tcaaactgtt ttcgaacaaa ctccagttga gttagctgaa cagggtgttg tcttcacaga
     4021 ctttcactca gctttagaag aaattccaga gctgatcgaa gaattcttca tgtcatctgt
     4081 taagtatgat gatgacaagt tggcggctta ccacacagct tactttaaca gtggtgctgt
     4141 actctatatt ccagataacg tagaaatcac agagccaatt gaaggaattt tctaccaaga
     4201 tagcgatagc aatgtgccgt ttaacaagca tattatgatt atcgctggta aaaattctaa
     4261 gattagttat ctggagcgtt tagagtcacg cggtgaagga agtgacaaag taactgccaa
     4321 tatcacagtg gaagtgattg cacgttctgg tgcgcaagtc aagtttgctg ctatcgaccg
     4381 tctaggtgaa aacgtcactg cctacattag ccgtcgtggt aaattaggca acgatgcaag
     4441 tattgactgg gctatcggtg tcatgaacga aggaaatgtc gttgctgatt ttgatagtga
     4501 cttgattggt aatggtagcc atgctgacct caaggttgta gctctttcaa gtggtcgtca
     4561 ggtacaaggg attgatactc gtgtaactaa ctatggctgc aactctatcg gaaatatcct
     4621 acaacatggg gttatccttg aaaaagcaac tttgactttc aatggtatcg gccacatcat
     4681 caagggtgct aagggagcag atgcgcaaca agagagccgt gttctcatgc tttcagacca
     4741 agcgcgttca gatgctaacc caattctttt gattgatgaa aatgatgtca ctgcaggaca
     4801 cgcagcgtct atcggacaag ttgatccaga agacatgtat tacctcatga gtcgtggatt
     4861 ggataaggca actgcagagc gtttggttgt tcgtggtttc cttggatctg ttatcgtgga
     4921 gattccagtc aaggaagttc gtgatgaaat gattgcaact atcgaagaga aattgtcaaa
     4981 acgctaaggg gaagcctatg ttagatgtag aagcgattcg caaggatttt ccaattttag
     5041 atcagattgt caatgatgaa cctctggtct atctggacaa tgctgcgacg acacaaaaac
     5101 cactagtagt tctgaaagct attaacagtt actatgagca ggacaatgcc aatgttcacc
     5161 gtggtgtcca taccttagcg gaacgagcga cagcttctta tgaagctgct cgtgaaacca
     5221 ttcgtaagtt tattaatgca ggctctacaa aggaagttct ctttaccaga ggaacgacaa
     5281 ccagccttaa ctgggtggca cgctttgctg aggaaattct cactgaggga gaccaggtct
     5341 tgatttcagt aatggaacac cattctaata tcattccatg gcaggaagct tgtcgaaaga
     5401 ctggagcaga gcttgtctat gtctatctta aagacggtgc cttggatatg gaggatttgc
     5461 gagctaaatt gactgataag gttaaatttg tttccctagc tcatgcctcc aatgttcttg
     5521 gtgtggtcaa tccgatcaag gaaatcactc aattagccca ccaagttggg gcaatcatgg
     5581 tagtggatgg tgctcaatct acacctcata tgaagattga tgtccaggac ttggatctgg
     5641 actttttcgc cttttcgggt cacaagatgg ctggtccgac tggtatcggt gtcctttacg
     5701 gcaaagaaaa gtatcttgag caaatgtctc cagtagaatt tggcggcgag atgattgatt
     5761 ttgtctacga gcaatccgct agttggaagg aattgccttg gaaatttgag gctggaacgc
     5821 caaatatggc aggagctatt ggacttgcga ctgcagttga ttatctggaa aagattggta
     5881 tggatgccgt tgaagctcat gaacaggaat tgattgcgta cgtctatcca aaactgcagg
     5941 caattgaggg attgaccatt tacggttctc aggatttggc tcaacgttcg ggtgttattg
     6001 cctttaacct aggtgatctc catcctcacg atcttgcgac ggctctggat tatgaaggag
     6061 tggctgttcg tgctggtcac cattgtgcgc aacccttgct tcagtatttg gaagtcccag
     6121 cattagctcg tgcaagtttt tatatctaca ataccaaggc agattgcgac aaactagtcg
     6181 atgccctaca aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat
     6241 atggcagtgg tagcagacca ttcgaaaaat ccacatcacc aagggaagtt agaagatgct
     6301 gggcaaatca gtctcaacaa tccgacttgt ggggatgtca tcaacctctc tgtcaagttt
     6361 gatgcagagg accgtttgga agatattgct tttctaaatt caggatgcac gatttcaact
     6421 gcttctgcta gtatgatgac agatgtcgtt ttaggaaaaa ccaaacaaga aattttagaa
     6481 ctggcgacta ttttttctga aatggttcaa gggcaaaaag atgagcgtca aggccaactt
     6541 ggagacgcgg cattcttgtc aggtgttgcc aaattccctc aaagaatcaa gtgtgcaacc
     6601 ctagcttgga atgcccttaa gaaaacaatt gaaaatcaag aaaaacagta agacaagttt
     6661 cttttgtctt atgaattatt agaaatgaag aaagaaagga tactatggct gaagaaagag
     6721 tagaaccaaa accaattgac cttggtgaat ataaatttgg tttccatgac gatgtagagc
     6781 ctgtcttatc gacaggaaaa ggactcaacg aaggtgttat tcgtgaatta tctgctgcta
     6841 agggtgagcc tgagtggatg ttggagttcc gtttgaagtc ttatgaaacc ttcaaaaaaa
     6901 tgcccatgca aacttgggga gcagacttgt cagagattga ctttgatgac ttaatctact
     6961 accaaaaacc atctgacaaa ccagcccgtt cttgggatga tgtacctgaa aagattaaag
     7021 aaacctttga acgtatcggg attccagaag ctgaacgtgc ttatttagca ggggcttctg
     7081 cccagtacga gtcagaagtg gtttaccaca acatgaagga agagttccaa aaattaggta
     7141 ttatctttac agatacagat tccgcactca aggaataccc agacttattt aaacaatact
     7201 ttgcgaagtt ggtaccgccg acagataaca agttggcagc cctcaactca gcagtatggt
     7261 cgggtggaac ttttatctac gtgccaaaag gtgtcaaggt agatattcca cttcaaactt
     7321 atttccgtat caataacgaa aatataggtc agttcgaacg taccttgatt atcgttgatg
     7381 agggagcaag cgtccactac gtagaaggat gtacagcacc aacatattca agcaatagct
     7441 tacacgctgc cattgtagaa atttttgctt tggacggagc ttatatgcgt tatacaacta
     7501 tccaaaactg gtctgataac gtctataact tggtaacaaa gcgtgctaag gctcaaaagg
     7561 atgccactgt tgagtggatt gatggaaact tgggtgccaa aacgactatg aaatatccat
     7621 ctgtttacct tgatggagaa ggagcgcgtg gtaccatgct ctctatcgcc tttgctaatg
     7681 cagggcaaca ccaagacacg ggtgctaaga tgattcacaa tgctccacat accagctcgt
     7741 ctattgtgtc taaatccatc gctaaaggtg gaggaaaggt tgactaccgt ggacaagtca
     7801 cctttaacaa gaactctaag aaatctgttt cccacattga atgtgatacc attatcatgg
     7861 atgacttgtc agcatcagat actattccat ttaatgaaat tcacaactcg caagtggctt
     7921 tggaacacga agccaaagta tctaagattt cagaagagca attgtattat ctcatgagcc
     7981 gtggattgtc agaatctgag gcaactgaaa tgattgtcat gggatttgta gaacccttta
     8041 caaaagaact tccaatggaa tacgcagttg agctgaaccg cttgattagc tatgaaatgg
     8101 agggatcagt tggataaaat ttgattttat gctcttcgaa aatctcttca aaccacgtca
     8161 gcatcgcctt accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac
     8221 agtgttttga gcaacctgcg gctagcttcc tagtttgttc tttgattttg agtattagat
     8281 ttactcaaaa tcaaggattt tgaagatgaa cttgtatcaa aaaatcgcgg tttaaaatcg
     8341 cgatttttta taatttctcg ttaacaaagc ggacaaactg attccaccaa acttttaaga
     8401 agaaggcttt ttcaattttc ttgtctgcta ccatttcgaa actagggcgc tctgtggtga
     8461 tgtaaccttg accaatcaag tccttgtctt cataagtcaa atggccaacc actgttccag
     8521 cttcaagtgg tgctgggatt gctttggaat caggtgtgaa ttgaacagat tgggaagatt
     8581 gattcccaac acgttcgatt agatagatat cctctggagc cactgcagtt actgtatctt
     8641 cttttccatc ttgtacaggg gctttgctat cttgataggc atcgccttgt tgaacgattt
     8701 tgcgaagtgt aaatgtagaa gaaatataat ccattaggga agatgtagct gtaaatcgag
     8761 cgtaaggatt attgtcttga tgatctgcat ttaaaacaac tgtgatgact ctcatgcctt
     8821 tttcgacagt agtaccaaca aaagactctc cagccttatc tgttgttcct gtttttagcc
     8881 catcaaaacc accacggtaa gcaggcatac cttctaacat gtagttggtt gaagtgattg
     8941 tcatcccagc aaaagtagaa gaaggttttt tggtgatttc taagacttgt gggtattttt
     9001 tgatgaggtt gcgagcaacg atagcgacat cataagcact aagcttattt tcctcatctt
     9061 ttttagaacc tgggtaaatg ttatccccta gagtttcatt gttaagacct gtcgtattga
     9121 caacagtggc atcctgaatt ccccattcca agagttttgc ccgcatcata tcgacgaaat
     9181 ctttttctga gccagcaatt ttctcagcta gggcaatagc ggcgctgttg gcactagata
     9241 ccagagttgc ttcaagcaac tcttcgacag tataattacg ggcctccata ggaatattac
     9301 tggcttcaga atttgtcgtc aattgataag gataatcaga aatatctaca ggagtggaga
     9361 gggtaatact tccgttttcc aaagcttcat agaccagata aacagtaatc aattttgtta
     9421 tggaagcaat ttcgacaggt tgcgttgcat ccttctcata gagaatttta ccagtatttg
     9481 cctcaacagc aatcgcatgt ttagcggcaa tggtaaaatc ttgagcaaca gcagtagaag
     9541 caccccctaa aagagagaca gttaacaaag ttaaaaatat ttttttcata gtagtcttat
     9601 tctatcataa agaaaaaaaa tattcttgct ttaataattc atctgttaag ctttttgaaa
     9661 atatggtaaa ataaagtgag ggaggtaact catgtttcgt agaaataaat tatttttttg
     9721 gaccacagaa attttactct taaccatcat cttttaccta tggagacaga tggggtcttt
     9781 gattaaccct tttgttagcg tgcttaatac aattatgatt ccatttttat tagggggctt
     9841 tctttattat ttgacaaacc ctattgttac tttcttaaat aaagtctgta aactcaatcg
     9901 tttgcttggt attttaatta ccttgtgtac tttggtctgg ggaatggtca taggtgttgt
     9961 ctatctctta cctattttga ttaatcagtt atctagtttg attatatcta gtcaaactat
    10021 ttatagtcga gtacaagact taatcataga cttatctaat tatcctgcgc tccagaattt
    10081 ggatgtagaa gctacaattc agcagttaaa cttatcctat gttgatattc ttcaaaatat
    10141 cctaaatagc gtatcaaata gtgtggggag cgtcttgtca gctcttatca gtactgtttt
    10201 gattttgatt atgactccag tttttttggt ttatttctta ttagatggac ataaattctt
    10261 gcccatgctt gaaagaacga ttctaaagag ggatcgcttg catattgcag gcttattaaa
    10321 gaatttaaat gcgacgattg ctcgctatat tagtggagtt tcgattgacg caatcattat
    10381 aggttgtttg gcttatattg gctatagtat tattggttta aaatatgctt tagtttttgc
    10441 cattttttct ggtgtagcca atttaattcc ttatgtgggg ccaagtattg gtttgattcc
    10501 tatgatcatc gcaaatatat tcactgatcc ccatagactg ctgattgcag tgatttatat
    10561 gcttgttgtt cagcaggtag atggcaatat cttatatcct cgaattgtag gaagtgttat
    10621 gaaggttcat ccaatcacga ttttagtttt acttttgttg tcaagcaata tctatggtgt
    10681 agttggaatg attgtcgcag tgccaaccta ttctatcttg aaagaaattt ctaagttctt
    10741 atcccgtttg tatgaaaatc ataaaataat gaaagaacga gaaagagaat tagctaagta
    10801 aaagtcagga gaaccctgat ttttctttac tggaagtggc ctttagatta gaagactgaa
    10861 aataagttaa agtcttaaac taattttcac agttaagaat agtagaagtt aatctgataa
    10921 aaatcgaaaa aaccagtgga attccgtgtc agggtaagtt ccactggttt tcatagtcta
    10981 ttaaagttcg aatgaaacct atttatagta tattgaaact agaatagtac acctctaatt
    11041 ctaaaacatt gttagaaatc gatttgactg tcctgatcta ttcgtcctat tcttatttca
    11101 ttttactata ttttggtgca ataagtgaaa agtagtccga ataatataag gattgatttt
    11161 atagttttta aactcaaatg aattaaaata aagagagtac gaaaattctc atctgaaagt
    11221 attttagaat aattttcttc gtgaatttct tcaaaacaga tagcttcatc ttaggtatgt
    11281 gttaattgga tttcgtaagc tctatttaca atcgtaaagt tatgcactga aaaagttgta
    11341 gttagtcttc cagtttgcta aatttctcga atagtatctt ttttaggtat gtgatttctt
    11401 tttgcatttt tgagttagat aaggtataat ggttttattg tcttttgggg tcgttacgga
    11461 ttcgacaggc attatgaggc atattttgcg actcgtgtgg cgacgtaaac gctcagttaa
    11521 atataactgc aaaaaataac acttcttacg ctctagctgc ctaaaaacca gcaggcgtga
    11581 cccgatttgg attgctcgtg ttcaatgaca ggtcttatta ttagcgagat acgattaagc
    11641 cttgtctagc ggcttgataa gagattgata gactcgcagt ttctagactt gagttatgtg
    11701 tcgaggggct gttaaaataa tacataacct atggttgtag acaaatatgt tggcaggtgt
    11761 ttggacgtgg gttcgactcc caccggctcc attattcctt tgcattcttt tgcattcctt
    11821 ggtaaaacgt tgttaaatca acgtttttta tttttatctt tggtattcct ttgcattctt
    11881 ttgctaaaaa gggagtcaca aacagaccct attttaaaaa aaggatagaa aaaaggatac
    11941 aacatttgtc gcatcctaaa aataatcttt tttccacgga agacatggga ttcgaaccca
    12001 cgcacgctat tacacgccta ccgcgtttcc aacacggcct cttaagcctc ttgagtaatc
    12061 ttccaatact tactcaaata gtctaccata aaggctctta tcttgcaata aaaattctag
    12121 aaatatgaaa aatgatagat tttgaaagaa aatgataaaa aatgcttgac ttcgaaagaa
    12181 agtatgatag aatgaatagt gtaaacgata acaggaggtg attcagtgtt aaaaacagaa
    12241 cgtaaacaac taattttaga ggagttaaat caacatcatg tagtttctct agaaaaatta
    12301 gttagtttgc tagaaacgtc agaatcaacg gttcgaagag acttggatga gttggaagcg
    12361 gaaaacaagc ttcgtcgtgt gcatggtgga gcagaactcc cccactcctt acaggaagaa
    12421 gaaaccattc aagaaaaatc tgtcaaaaac cttcaagaaa agaagttgct ggctcagaaa
    12481 gcagcctctc tcattaaaga aaaagatgtc atctttatcg atgctggaac aacaactgct
    12541 tttttgattc atgaattggt caataagaat gttacagttg tgaccaactc cattcaccat
    12601 gccgctcagt tggttgaaaa gcagattcca gctgtcatgg ttggaggaaa cgtcaagacg
    12661 gcgacagatg ctagtatcgg gggcgttgct cttaaccaga ttaaccaatt gcactttgac
    12721 cgtgccttta tcggaatgaa tggtgttgac gatggctatt atacgactcc tgatatggag
    12781 gagggagctg tgaaaagatc tattttggag aatgccaagc agacctacgt cttggtggat
    12841 tcgtcaaaaa ttggacaaac ttgctttgcc aaggtagcac cactcaaacg cgctatcgtt
    12901 atcactagtc aagggcatga gctcttgcag gttattaagg agaaaacgga ggtaatagaa
    12961 gtatgattta tacagtcaca ctcaatccat ccattgacta tatcgttcgt ttggaccaag
    13021 tcaaagttgg tagtgtaaat cgtatggaca gtgatgataa gtttgctggt gggaaaggaa
    13081 tcaatgtcag ccgtgtcttg aaacgtttga atataccaaa tacagcgacg ggatttatcg
    13141 gtggctttac tggtaaattt atcacagata ctttagcaga ggaagaaatc gagacacgtt
    13201 ttgtccaggt ggcagaagat actcgtatca atgttaaaat caaagcagac caagaaacag
    13261 aaatcaacgg aacgggtcca actgttgaat cggttcagct agaagaattg aaagctattt
    13321 tatctagtct gacagcagaa gatacagttg tctttgcagg ttcaagtgct aaaaatctag
    13381 gcaatgttat ctataaggat ttgatttcct tgacgcgcca gactggtgcg caagtggtct
    13441 gtgactttga aggacagacc ttaattgata gtttggacta ccagcctctt cttgtaaaac
    13501 caaacaatca tgaacttgga gcgatttttg gggttaaact cgaaagttta gatgaaattg
    13561 agaaatacgc tcgtgagtta ctggctaagg gtgctcaaaa tgttattatc tctatggctg
    13621 gtgatggtgc ccttcttgtc acatctgagg gagcttactt cgctaaacca atcaaaggaa
    13681 cagtcaaaaa ttcagttgga gctggtgatt ctatggttgc tggattcaca ggtgaatttg
    13741 tcaaatcaaa agacgcagta gaagccttca aatggggagt ggcttgcgga acggcaacta
    13801 ccttctcaga tgacttggca acggcggaat ttattaaaga aacatatgga aaagttgagg
    13861 tagaaaaacg atgaaaattc aagacctatt gagaaaagat gtcatgttgc tagatttgca
    13921 ggcaactgaa aaaacagctg tcatcgacga gatgattaaa aatttgacag accacggtta
    13981 tgtaacagat tttgaaacat ttaaagaagg aattttggcg cgtgaagctt tgacttctac
    14041 tggtttgggt gatggaatcg caatgcctca cagcaaaaac gctgctgtca aagaagcgac
    14101 agttctattt gctaagtcaa ataagggtgt tgactacgag agcttggatg gacaagcaac
    14161 tgacctcttc ttcatgattg cagctccaga aggtgccaat gatactcact tggcagcctt
    14221 ggcagaattg tctcaatact tgatgaaaga cggttttgca gacaaacttc gtcaagcaac
    14281 atctgcagac caagttatcg aactttttga ccaagcttca gaaaaaactg aggaacttgt
    14341 tcaagcacct gctaatgact ctggtgactt tatcgtagct gttacagctt gtacaacagg
    14401 tattgcccac acttacatgg cccaagaagc ccttcaaaaa gtagctgctg aaatgggggt
    14461 tggtatcaag gtcgaaacca acggtgctag cggtgttgga aatcaactaa ctgcagaaga
    14521 tatccgtaag gctaaagcta ttatcattgc agcagacaag gccgttgaaa tggatcgatt
    14581 tgatggaaaa ccattgatca atcgtccagt tgctgacggt atccgtaaga cagaagagct
    14641 aattaacttg gctctttcag gagatactga agtctaccgt gccgctaatg gtgcaaaagc
    14701 tgcaacagcc tctaacgaaa aacaaagcct tggtggtgcc ttctacaaac acttgatgag
    14761 tggtgtatct caaatgttac cattcgttat cggtggtggt atcatgattg cccttgcctt
    14821 cttgattgac ggtgctttga gtgttccaaa tgaaaacctt ggcaatcttg gttcttacca
    14881 tgagttagct tctatgttca tgaaaattgg tggagctgcc tttggtttga tgcttccagt
    14941 ctttgcgggt tatgttgcct actctattgc tgaaaaacca ggtttggtag caggtttcgt
    15001 ggctggtgct attgccaaag aaggttttgc ctttggtaaa attccttatg ccgcaggtgg
    15061 tgaagcaact tcaactcttg caggtgtctc atctggtttc ctaggtgccc ttgttggtgg
    15121 atttatcgca ggtgccttgg ttcttgccat caagaaatac gttaaagttc ctcgttcact
    15181 cgaaggtgct aaatcaatcc ttctattgcc acttcttgga acaatcttga caggatttgt
    15241 tatgctagct gtgaatatcc caatggctgc aatcaacact gctatgaatg acttcctagg
    15301 tggtcttgga ggaggttcag ctgtccttct tggtatcgtc cttggtggaa tgatggctgt
    15361 tgacatgggt ggaccagtta ataaagcagc ttatgtcttt ggtacaggta cgcttgcagc
    15421 aactgtttct tcaggtggtt ctgtagccat ggcagcagtt atggctggag gaatggtgcc
    15481 accacttgca atctttgtcg caactcttct tttcaaagat aaatttacta aggaagaacg
    15541 taactctggt ttgacaaaca tcatcatggg cttgtcattt atcactgagg gagcgattcc
    15601 atttggtgcc gctgacccag ctcgtgcgat tccaagcttc atccttggtt cagcagtagc
    15661 aggtggactc gttggtctta ctggtatcaa actcatggcg ccacacggag gaatcttcgt
    15721 tatcgccctt acttcaaatg ctctccttta cctcgtttct gtcttggtag gagcaatcgt
    15781 aagtggtgtg gtttatggtt acctacgcaa accacaagca taaaaaatag aaaaatgaaa
    15841 agattggacc gtttggtgca gtctttttct cttcccgaaa tgcctgtgaa atatggtata
    15901 atagaagaat ggcaaacaag aatacaagta caacaagacg gagaccgtct aaagcagaac
    15961 tggaaagaaa agaagcgatt caacgaatgt tgatttcgtt aggaattgcg attttattga
    16021 ttttcgcagc cttcaaatta ggggctgcag gtataaccct ttataattta attcgcttgc
    16081 tagtgggtag cctagcttat ctggcgatat tcggcctatt aatctatctc ttctttttca
    16141 agtggatacg aaaacaggaa ggactcttat ctggtttttt caccatattt gctggcttac
    16201 tcttgatttt tgaggcctac ttggtttgga aatatggttt ggacaagtcc gttctaaaag
    16261 ggaccatggc tcaggttgtg acagatctga ctggttttcg aacgactagc tttgctggag
    16321 ggggcttgat cggggtcgct ctttatattc caacagcctt tctcttttca aatatcggaa
    16381 cttactttat tggttctatc ttgattttag tgggttctct cctagtcagc ccttggtctg
    16441 tttacgatat tgctgaattt ttcagtagag gctttgccaa atggtgggaa gggcacgagc
    16501 gtcgaaaaga ggaacgcttt gtcaaacaag aagaaaaagc tcgccaaaag gctgagaaag
    16561 aggctagatt agaacaagaa gagactgaaa aagccttact cgatttgcct cctgttgata
    16621 tggaaacggg tgaaattctg acagaggaag ctgttcaaaa tcttccacct attccagaag
    16681 aaaagtgggt ggaaccagaa atcatcctgc ctcaagctga acttaaattc cctgaacagg
    16741 aagatgactc agatgacgaa gatgttcagg tcgatttttc agccaaagaa gcccttgaat
    16801 acaaacttcc aagcttacaa ctctttgcac cagataaacc aaaagatcag tctaaagaga
    16861 agaaaattgt cagagaaaat atcaaaatct tagaagcaac ctttgctagc tttggtatta
    16921 aggtaacagt tgaacgggcc gaaattgggc catcagtgac caagtatgaa gtcaagccgg
    16981 ctgttggtgt aagggtcaac cgcatttcca atctatcaga tgacctcgct ctagccttgg
    17041 ctgccaaaga tgtccggatt gaagcaccaa tccctgggaa atccctaatc ggaattgaag
    17101 tgcccaactc cgatattgcc actgtatctt tccgagaact atgggaacaa tcgcaaacga
    17161 aagcagaaaa tttcttggaa attcctttag ggaaggctgt taatggaacc gcaagagctt
    17221 ttgacctttc taaaatgccc cacttgctag ttgcaggttc aacgggttca gggaagtcag
    17281 tagcagttaa cggcattatt gctagcattc tcatgaaggc gagaccagat caagttaaat
    17341 ttatgatggt cgatcccaag atggttgagt tatctgttta caatgatatt ccccacctct
    17401 tgattccagt cgtgaccaat ccacgtaaag ccagcaaggc tctgcaaaag gttgtggatg
    17461 aaatggaaaa ccgttatgaa ctctttgcca aggtgggagt tcggaatatt gcaggtttta
    17521 atgccaaggt agaagagttc aattcccagt ctgagtacaa gcaaattccg ctaccattca
    17581 ttgtcgtgat tgtggatgag ttggctgacc tcatgatggt ggccagcaag gaagtggaag
    17641 atgctatcat ccgtcttggg cagaaggcgc gtgctgcagg tatccacatg attcttgcaa
    17701 ctcagcgtcc atctgttgat gtcatctctg gtttgattaa ggccaatgtt ccatctcgtg
    17761 tagcatttgc ggtttcatca ggaacagact cccgtacgat tttggatgaa aatggagcag
    17821 aaaaacttct tggtcgagga gacatgctct ttaaaccgat tgatgaaaat catccagttc
    17881 gtctccaagg ctcctttatc tcggatgacg atgttgagcg cattgtgaac ttcatcaagg
    17941 ctcaggcaga tgcagactac gatgagagtt ttgatccagg tgaggtttct gaaaatgaag
    18001 gagaattttc ggatggagat gctggtggtg atccactttt tgaagaagct aagtctttgg
    18061 ttatcgaaac acagaaagcc agtgcgtcta tgattcagcg tcgtttatca gttggattta
    18121 accgtgcgac ccgtctcatg gaagaactgg agatagcagg tgtcatcggt ccagctgaag
    18181 gtaccaaacc tcgaaaagtg ttacaacaat aaaaaaatag cttctttccg agtttggagg
    18241 gaagctattt tagtggctat tgattgcttt tattttctga agttggcgca ttggactgtt
    18301 tttcgttttc agtagcaggt ttacttgaag caggagtaga agagtcctga gttgctgttt
    18361 tctgatcttc ttttttctct tccttgacgc tagattttgg tgtttcctct tgctgtgttt
    18421 tttcttgact agtgttagtc tctttagttg gactggtgtt ttccttaggg gattcctttt
    18481 ggatttcttt gacaatggtt gtcgtctggc ttgtcgtagg ttctttttta atatttttgt
    18541 tattatccaa ggcgttcata atcgtgatac ttgcggtaat caagccaagg atactagcga
    18601 ttgtagcaac ggttttttga aagactgtaa agcctttttt gatgtgttct gtttttggtt
    18661 ttgaagttct acgatagtta gacatacatt ctctcctttg attatgattt attatactct
    18721 gtttctttaa aaaaatctta aaaaaagaga aattgccctt tcttgtcgca agctccgttt
    18781 catgatacaa tagaggaagt gattttagaa agcgtgagaa acatgattta ctttgataat
    18841 tcagcgacga ccaagcctta tcctgaagcc cttgaaacct atatgcaggt cgcttcaaaa
    18901 attttaggaa acccatctag tctccatagt ttgggagacc aagcaacacg aatcttagat
    18961 gcttctcgcc aacagattgc agatttaatc ggtaagaaaa gcgatgaaat cttctttacc
    19021 tctggtggaa cagaagggga taactgggtt atcaagggtg tggcctttga aaaagctcag
    19081 tttggcaagc acatcattgt ttcagccatt gaacatccag cagtcaaaga gtcagccctc
    19141 tggttgaaaa gtcaaggatt tgaagtggat tttgctccag ttgataagaa aggcttggtc
    19201 gatgttgagg cgttagcagg tttgatacgg cctgatacaa tcctcgtttc tatcatggct
    19261 gtgaacaatg aaatcggctc tatccaacct attgaggcta tttcagaatt cttggcagac
    19321 aagccgacta tttccttcca cgttgatggg gttcaggcgc ttaccaagat tccgactgaa
    19381 aagtatctga cagaacgagt ggattttgcg actttctcta gtcacaagtt ccacggggtt
    19441 cgaggtgttg gctttgtcta tatcaaatct ggcaagaaga ttacacctct tcttacaggt
    19501 ggtggccagg agcgagatta tcgttcgaca actgaaaatg tggcagggat tgcagcgaca
    19561 gccaaggccc tccgtttgtc tatggaaaag ctagatatct ttaggagcaa gactgggcag
    19621 atgaaggcag tgattcgcca agctcttctg aaccatccgg atatttttgt cttttcagat
    19681 gaggaaaact ttgcacctca tattctgact tttggaatca aaggtgttcg aggtgaagtc
    19741 atcgttcacg cctttgaaga ctatgatatt ttcatctcaa caacctcagc ttgttcatct
    19801 aaggcaggaa aaccagccgg taccttgatt gccatgggag tggacaaaga taaggccaag
    19861 tcagctgtgc gtcttagcct agacttggaa aatgatatga gtcaggtcga gcagtttttg
    19921 accaagttaa aattgattta caatcaaact agaaaagtaa gataggagca ttcatgcagt
    19981 attcagaaat tatgattcgc tacggagagt tgtcaaccaa gggtaaaaac cgtatgcgtt
    20041 tcatcaataa acttcgtaat aatatttcgg acgttttgtc tatctatacc caagttaagg
    20101 taacagcaga tcgcgaccgt gcccacgctt acctcaatgg agctgattac acagcagttg
    20161 cagaatctct caaacaagtt tttggaattc aaaacttttc tcctgtttat aaggttgaaa
    20221 aatctgtaga agttttgaag tcttctgtcc aagagattat gcgggacatc tacaaggaag
    20281 gtatgacctt taagatttct agcaagcgta gcgaccacaa ctttgaactt gatagtcgtg
    20341 aactcaacca aacacttgga ggggctgtat tcgaagccat tccaaatgtg caagttcaaa
    20401 tgaaaagtcc tgacatcaat cttcaggtgg agattcgtga agaagcagcc tatctttctt
    20461 atgaaaccat tcgtggggct ggtggtttgc cagttggaac ttcaggtaaa gggatgctca
    20521 tgttgtcagg agggattgac tcacctgtag caggttatct tgctcttaag cgtggggtgg
    20581 atatcgaggc agttcacttt gctagtccac catatactag tcctggtgcc ctcaagaaag
    20641 cgcaggactt gacccgtaaa ttgaccaagt ttggcggaaa tatccagttt atcgaggtgc
    20701 ctttcacaga gattcaagag gaaatcaaag ccaaagcgcc agaagcttat ttgatgactc
    20761 taactcgtcg ctttatgatg cggattactg accgtattcg tgaggtacga aatggtttgg
    20821 ttatcatcaa tggggaaagt ctaggtcaag tagccagcca aacccttgaa agtatgaagg
    20881 ctatcaatgc tgttaccaac actcccatca ttcgtcctgt ggttaccatg gacaagttgg
    20941 aaatcattga catcgcccag gaaatcgata cctttgacat ttcaatccaa ccgtttgaag
    21001 actgttgtac catttttgca ccagatcgtc caaaaacaaa tcctaaaatt aagaatgcgg
    21061 agcagtacga agcgcgtatg gatgttgaag gcttggttga gcgagcagtg gctggaatca
    21121 tgattactga aatcacacct caagccgaaa aagatgaagt tgatgacttg attgacaatc
    21181 tgctctaatt cagaaaatcc aaaagaatag cgaaaatcag taaaaaaagt tagttttttc
    21241 tctaaaaaca ggtaaaaaac taactttttt tatttttatg atataatgat ataaaatttt
    21301 gaatatagag agttttctga caatgaatca atcctacttt tatctaaaaa tgaaagaaca
    21361 caaactcaag gttccttata caggtaagga gcgccgtgta cgtattcttc ttcctaaaga
    21421 ttatgagaaa gatacagacc gttcctatcc tgttgtatac tttcatgacg ggcaaaatgt
    21481 ttttaatagc aaagagtctt tcattggaca ttcatggaag attatcccag ctatcaaacg
    21541 aaatccggat atcagtcgca tgattgtcgt tgctattgac aatgatggta tggggcggat
    21601 gaatgagtat gcggcttgga agttccaaga atctcctatc ccagggcagc agtttggtgg
    21661 taagggtgtg gagtatgctg agtttgtcat ggaggtggtc aagcctttta tcgatgagac
    21721 ctatcgtaca aaagcagact gccagcatac ggctatgatt ggttcctcac taggaggcaa
    21781 tattacccag tttatcggtt tggaatacca agacaaaatt ggttgcttgg gcgttttttc
    21841 atctgcaaac tggctccacc aaccgctata tcgagtgcca gaaactatcg cctgaccaac
    21901 gcatcttcat ctatgtagga acagaagaag cagatgatac agacaagacc ttgatggatg
    21961 gcaatatcaa acaagcctat atcgactcgt cgctttgcta ttaccatgat ttgatagcag
    22021 ggggagtaca tctggataat cttgtgctaa aagttcagtc tggtgccatc catagtgaaa
    22081 tcccttggtc agaaaatcta ccagattgtc tgagattttt tgcagaaaaa tggtaagtta
    22141 agaaaggaaa aaacgaaatg catattgaac atcttagcca ctggagtggt catcctaacc
    22201 gtgaaatgta ccttaaccgt tatggacatg gtgggattcc agttgtggtc tttgcttcat
    22261 caggtggtag tcacaacgaa tactatgatt ttggcatgat tgatgcctgt gcttccttta
    22321 tcgaggaagg ccgtgtccag ttctttaccc tatctagtgt ggatagtgag agctggttgg
    22381 ctacttggaa aaatgctcat gaccaagcgg aaatgcaccg tgcctacgaa cgttatgtga
    22441 ttgaggaggc cattctttta tcaagcacaa gacaggttag ttggatggca tgatgacgac
    22501 aggttgctct atgggagcct atcatgcact caatttcttc ctccagcatc cagatgtctt
    22561 taccaaagtg attgctctca gtggtgttta cgacgcacgt ttctttgtcg gtgattacta
    22621 caacgatgat gctatttacc aaaactcgcc agtagattat atttggaacc aaaacgatgg
    22681 ctggtttatt gaccgttacc gtcaggcaga gattgtgctg tgtacggggc ttggagcctg
    22741 ggaacaagat ggtttaccat ccttttacaa gctcaaagaa gcctttgacc agaaacaaat
    22801 tccagcctgg tttgctgaat ggggacatga tgtcgcccac gactgggaat ggtggcgtaa
    22861 acaaatgcct tatttcctcg gtaatctcta tttataaaag gagttaccta tgaattacct
    22921 tgttatttct ccctactatc cacaaaactt tcaacagttt accatcgaac tagctaataa
    22981 aggcatcaca gtcttgggaa ttggtcaaga gtcttacgag caattggatg agcccttgcg
    23041 caatagcttg accgagtatt ttcgtgttga taatcttgag aacatagatg aagtcaaacg
    23101 tgcagttgct tttctctttt ataaacatgg tccaattgac cgcatcgagt ctcacaatga
    23161 atactggctt gagctagacg caacactcag agaacaattc aatgtttttg gtgccaaacc
    23221 agaggatctc aaaaagacga aatataagtc tgaaatgaag aaacttttca aaaaagcagg
    23281 tgttcctgtg gtacctggag ctgttatcaa gacggaagca gatgttgatc aagcagtgaa
    23341 agaaatcggt cttccaatga ttgccaaacc tgataatgga gtgggagcag ccgcaacctt
    23401 taaacttgag acagaagacg atatcaatca cttcaagcaa gaatgggacc attcaaccct
    23461 ttatttcttt gaaaaatttg tcacttccag cgaaatctgt acctttgacg ggctcgtgga
    23521 caaggatgga aagattgtct tctcaacaac ctttgactac gcctatacac cgcttgacct
    23581 catgatttat aagatggaca attcttatta tgtgctcaag gatatggatc ctaaactgcg
    23641 caagtatggg gaagcaattg tcaaagaatt tggtatgaaa gaacggtttt tccatattga
    23701 gttcttccgt gagggggacg attatattac catcgagtac aataaccgcc ctgcaggtgg
    23761 ttttaccatt gatgtttata actttgctca ttccttggac ctttatcgtg gctatgcagc
    23821 tattgtcgca ggagaggagt tcccggcgtc agactttgaa actcagtatt gtttggctac
    23881 ttctcgccgt gcaaatgctc actatgttta ttcagaagag gatttgcttg ccaaatatag
    23941 ccagcagttc aaggttaaaa aagtcatgcc agctgccttc gcggaacttc aaggagatta
    24001 cctgtatatg ctgacaactc cgagtcgaca agaaatggat cagatgattg ctgatttcgg
    24061 acaacgtcaa gaataagaac tatcggatta aggaaattca ctcccttaat ccttttgttt
    24121 tgtctggtaa aaaataagag catcttaaca aggtagctat cataaaactt gttcgataac
    24181 tatttgaagc aggattaggt ggctagaaat tgaattttaa catttcaatt tagtcatagt
    24241 attgtgtttt cgtatcctta aatcagctaa aaggatccat gacgacacct atacgatata
    24301 gttttcagga taccaaacca gtctattaat actcaatgaa aatcaaagag caaactagga
    24361 agctagccgc aggttgctca aaacactgtt ttgaggttgt ggatagaact gacagagtca
    24421 gtatcatata cctacggcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat
    24481 aaaatattca ggtgacgcat agatatagtt aattgaagct ttgtttgaaa tctgataaaa
    24541 taatgatatt actaagtttt aaaaactaaa gaaaagggaa gatatgatta caggcgaatt
    24601 aaaaaataaa atcgaccagc tgtgggaaat tctttggaca gaaggaaacg caaatccttt
    24661 aacaaatatt gaacagttga cttatctctt atttatgaaa gatttggata gtgtcgagct
    24721 tggacgtgaa agtgatgctg aatttctagg gattccttat gagggagttt ttccaaaaga
    24781 taaacctgaa taccgttggt caacttttaa aaatatagga gatgctcagg aagtttatcg
    24841 tttaatgact caggagattt ttccgtttat taaaaatctc aagggggata cagatgatac
    24901 agccttttca cgatatatgc gagaagctat ttttcaaata aataaacctg ctacgcttca
    24961 aaaggcaatt tctatcttag atgtttttcc aactagggga ttagatgtag attttgataa
    25021 tgacaaacaa agtattactg atatcggaga tatctatgaa tatctgttat caaaattgtc
    25081 gaccgcaggt aaaaatggac agttccgtac acctcgtcac atcatcgata tgatggttga
    25141 gttgatgcaa ccgactatca aagatatcat ctcagatccc gctatgggtt ctgctggctt
    25201 cttagtatct gctagccgtt acttaaagcg taagaaagat gaatgggaaa ccaatacaga
    25261 taatatcaat cattttcata atcagatgtt tcgtggaaat gatacggata cgactatgtt
    25321 gagacttggg gcgatgaaca tgatgctaca tggagtagaa aatccacaaa tcagttacct
    25381 tgactcgctg tctcaagata atgaagaagc cgataaatat actttggttt tagcaaatcc
    25441 tccttttaag ggctcacttg actacaattc aacctctaat gaccttcttg caaccgtaaa
    25501 aaccaaaaaa acagaattac tctttctttc tcttttcttg cgaactttaa aaccaggtgg
    25561 acgagcagca gttatcgtac ctgatggtgt cctttttggt tcgtctaaag ctcataaagg
    25621 aattcgtcag gaaattgtag agaatcataa gcttgatgct gtaatctcaa tgcctagtgg
    25681 tgtgttcaag ccttatgctg gagtttcaac tgccattctc atctttacaa aaactggtaa
    25741 tggtggtact gacaaagtct ggttttacga tatgaaagcg gatggtttaa gtttggatga
    25801 taagcgacaa ccgattagcg acaatgatat tccagatatt atcgaacgct ttcatcatct
    25861 tgaaaaagaa gcagaacgtc agagaacgga tcaatctttc tttgttccag ttgctgagat
    25921 aaaggaaaat gattatgatt tgtctatcaa taaatataaa gagattgagt atgaaaaagt
    25981 tgagtatgaa ccaacagaag tcatattaaa gaaaatcaat gatttagaaa aagaaattca
    26041 agctggcttg gctgaattgg aaaaattact caagtaggga ggtggctgta tgaaaaaagt
    26101 gaagttgggg gaagtttgtg agattttatc tggttacgct tttaaatcat cacaatttaa
    26161 tgataacaaa attggtctcc ccttaatacg aattcgagat gtagaaagag gtttttctga
    26221 tacctacttt gaaggaactt atcccgaaga atatcttatt aaaaatggag acttattgat
    26281 tacaatggat ggcagtttta tattgaaaaa atgggagggg gatttagcgc tacttaatca
    26341 acgtgtctgt aaaattaaaa ttacggataa aagtgtagat gaaggttata tatcttggtt
    26401 gattcctaaa tttttaaaag aaattgaaga taagacccct tttgttacag tgaaacatct
    26461 ttcagtagct aaaataaaag atatctcatt tgtattgcct aataaactag aacaaaagct
    26521 aattgcaaaa aaactaaata cgataagtca aatttatgat tttcgtaaaa ttcaatcaga
    26581 aaaatttaac gagctcg
//
LOCUS       DAVHSH010000021        24859 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000021 DAVHSH010000000
VERSION     DAVHSH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.021"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            111..275
                     /locus_tag="VVR08_001076"
     CDS             111..275
                     /locus_tag="VVR08_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6075005.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            359..925
                     /gene="amaP"
                     /locus_tag="VVR08_001077"
     CDS             359..925
                     /gene="amaP"
                     /locus_tag="VVR08_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU6075006.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            937..1107
                     /locus_tag="VVR08_001078"
     CDS             937..1107
                     /locus_tag="VVR08_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU6075007.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1146..1754
                     /locus_tag="VVR08_001079"
     CDS             1146..1754
                     /locus_tag="VVR08_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6075008.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1785..1988
                     /locus_tag="VVR08_001080"
     CDS             1785..1988
                     /locus_tag="VVR08_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6075009.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2098..2370)
                     /locus_tag="VVR08_001081"
                     /pseudo
     CDS             complement(2098..2370)
                     /locus_tag="VVR08_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2574..2861
                     /locus_tag="VVR08_001082"
     CDS             2574..2861
                     /locus_tag="VVR08_001082"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU6075010.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3139..3909)
                     /locus_tag="VVR08_001083"
     CDS             complement(3139..3909)
                     /locus_tag="VVR08_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU6075011.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSILGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3924..4772)
                     /locus_tag="VVR08_001084"
     CDS             complement(3924..4772)
                     /locus_tag="VVR08_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU6075012.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGLQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4769..6244)
                     /locus_tag="VVR08_001085"
     CDS             complement(4769..6244)
                     /locus_tag="VVR08_001085"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU6075013.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6568..7923)
                     /locus_tag="VVR08_001086"
     CDS             complement(6568..7923)
                     /locus_tag="VVR08_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6075014.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGCFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7933..8250)
                     /locus_tag="VVR08_001087"
     CDS             complement(7933..8250)
                     /locus_tag="VVR08_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6075015.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8267..8584)
                     /locus_tag="VVR08_001088"
     CDS             complement(8267..8584)
                     /locus_tag="VVR08_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6075016.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8599..9495)
                     /locus_tag="VVR08_001089"
     CDS             complement(8599..9495)
                     /locus_tag="VVR08_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU6075017.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9498..10760)
                     /locus_tag="VVR08_001090"
     CDS             complement(9498..10760)
                     /locus_tag="VVR08_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6075018.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTSFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWAMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11040..12218
                     /locus_tag="VVR08_001091"
     CDS             11040..12218
                     /locus_tag="VVR08_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU6075019.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12446..12892)
                     /locus_tag="VVR08_001092"
     CDS             complement(12446..12892)
                     /locus_tag="VVR08_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6075020.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRVQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12962..13621
                     /locus_tag="VVR08_001093"
     CDS             12962..13621
                     /locus_tag="VVR08_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU6075021.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSKVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            complement(13673..14824)
                     /locus_tag="VVR08_001094"
     CDS             complement(13673..14824)
                     /locus_tag="VVR08_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6075022.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINDQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14839..15570)
                     /locus_tag="VVR08_001095"
     CDS             complement(14839..15570)
                     /locus_tag="VVR08_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075023.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDENSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            15799..15900
                     /locus_tag="VVR08_001096"
                     /pseudo
     CDS             15799..15900
                     /locus_tag="VVR08_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(15872..16648)
                     /locus_tag="VVR08_001097"
     CDS             complement(15872..16648)
                     /locus_tag="VVR08_001097"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU6075024.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(16641..17864)
                     /gene="trpB"
                     /locus_tag="VVR08_001098"
     CDS             complement(16641..17864)
                     /gene="trpB"
                     /locus_tag="VVR08_001098"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6075025.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(17842..18441)
                     /locus_tag="VVR08_001099"
     CDS             complement(17842..18441)
                     /locus_tag="VVR08_001099"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU6075026.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(18428..19195)
                     /gene="trpC"
                     /locus_tag="VVR08_001100"
     CDS             complement(18428..19195)
                     /gene="trpC"
                     /locus_tag="VVR08_001100"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU6075027.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(19192..20196)
                     /gene="trpD"
                     /locus_tag="VVR08_001101"
     CDS             complement(19192..20196)
                     /gene="trpD"
                     /locus_tag="VVR08_001101"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU6075028.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(20207..20773)
                     /locus_tag="VVR08_001102"
     CDS             complement(20207..20773)
                     /locus_tag="VVR08_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU6075029.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(20770..22131)
                     /gene="trpE"
                     /locus_tag="VVR08_001103"
     CDS             complement(20770..22131)
                     /gene="trpE"
                     /locus_tag="VVR08_001103"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU6075030.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(22770..22850)
                     /locus_tag="VVR08_001104"
                     /pseudo
     CDS             complement(22770..22850)
                     /locus_tag="VVR08_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     misc_binding    complement(23011..23240)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23452..24453)
                     /locus_tag="VVR08_001105"
     CDS             complement(23452..24453)
                     /locus_tag="VVR08_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6075031.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(24561..24824)
                     /locus_tag="VVR08_001106"
     CDS             complement(24561..24824)
                     /locus_tag="VVR08_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075032.1"
                     /translation="MVFAFHLPPDELITNVIFKEKINSMLKCYIDRLLYVFINPTHFT
                     EKVNLQFYGSFFSYEFICREVGNILKNKGVKCNLNFFEGEEYL"
BASE COUNT         7829 a         5294 c         4046 g         7690 t
ORIGIN      
        1 ttgatttttt gatattaaaa taaaaaagga gggtaggcag tgttgtgatc aattattgct
       61 ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa aagtagttct atgggaatca
      121 tcgcaaatgt attcgctggt ttagtcgggg catatgcagg acaatctctt ttaggtagtt
      181 ggggtccatc aatcgctgga atggctttgc tcccatctat tgtaggtgca gcgattgtga
      241 ttactgtagt gtcattcttt acaggtagaa agtaaacttt tcgccagtaa agttagcaaa
      301 ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag gattgtatat
      361 gtcaaaagca aagaaaatat gtttcattat tttctgtatt ttaatcttga caattttcct
      421 tcctgttttg atagattatc atcaagttag tgatctaggt attcatctac ttagctggag
      481 acagaactcc gtagttgaat tctatcttgc tagatatgtc ttttggggga cagtggttct
      541 atcaacttta gttttattat ccattttagt tgtgatgttt tatcctaaac gttacttgga
      601 aatccaactt gaaactaaaa acgatacatt aaaattaaag aattcggcaa tcgaaggttt
      661 tgttagaagt ttggtgagtg atcatagatt gatcaagaac ccaactgttc atgtaaattt
      721 acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag acaacatcgc
      781 tgacagatgc caaataattc aaaatgaaat aactaatgga ttgaagcagt tttttggtat
      841 tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac caaccaaaac ctcaaaacaa
      901 aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa acaatatcga
      961 tatccaatta tcgctggtct cataggcgta tttctggctt gtttgattgt ctcctttggc
     1021 ttcttcaaaa caatatttgt attgatttta ggagcactgg gagttgcagc tggattatat
     1081 atcgaaaaaa actatataga taaataaaaa aataaaaatt actaatttaa ttaaaggagt
     1141 ttcatatgtc aaacgaaaaa aacacaaaca ctaacgtaga aaagaaagat gctactgttg
     1201 tagctcacga aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg
     1261 gtctttcact agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc
     1321 ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta
     1381 aaacacaagt tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt
     1441 tatattcaga aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa
     1501 ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact
     1561 cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag
     1621 aacaattcga aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag
     1681 ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca
     1741 ctcgtgtaaa ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa
     1801 aattaaatca agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa
     1861 aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gtcgccgaag
     1921 atgccaaaga cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg agtggcgacg
     1981 ataaataagg ttaaaagtta ctttatcttt ttagtaacat tagtcaaaag agtctgagtc
     2041 aagatgattc tcagaaaaca aaaagctagg gattcccaat tgcggaactc tagcttttta
     2101 attttgcctc tttctcttat tatatttcag caggttgttg gccatgagta cgaatcccat
     2161 gtcaattctc acttgacgct tccctctcag atgacatctc ttataaccca aacaaacctt
     2221 tatctgccca aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt
     2281 ggaagataaa agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata
     2341 cagtcccttt tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct
     2401 gtttgctttc tatctaccct ttttcatgat atattttcgt acaggttctt caatagtttc
     2461 tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata atgttcttgt ggcatattca
     2521 ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa caggtatagt caattgattg
     2581 tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc agaatccatc caagggtggc
     2641 tggcacaatt tctagtgaac ctctttaaat ctattacgtt tgactgtgga aaagagtttt
     2701 caaaatggaa agatatttcc aatcatcacg atagtgagag cttttttgcg aatctaggat
     2761 gttcaagaca gcggtgtctc aacgaacatt caaatagact tttaaggtgt catgacttgc
     2821 caaagcagac agatttcaac gaagtcagtc aagaatttta ggctggacaa aaactcaatt
     2881 tcaggagaaa atgaaataaa tattcccaca ataaaacgca tagtatcaaa gtttttccaa
     2941 cacctgatat tatgcatttt ttaattttaa agactttttc ccagcctcaa gaaatcacat
     3001 cccacctaaa tcctttggat accaaatacc tcatcaggta ttttctgagt tggtaagact
     3061 gtctagctta atttgacaaa tggagggcgt taaatccagt ttttacagga agtctattta
     3121 aatattttca cactgacctt acaaaatatg aaataaatta tataaagtca ttcccatgac
     3181 aaagaataac atccctttaa aacagtatct tacccaattt tcaggtaaga cttttgatac
     3241 aaccgtcccc aatacccctc cgcatataga agcaagaaaa ataactggaa caggtgctaa
     3301 atgatactga tttaaacctg taaccacaac aattgtagcc aaatgagaca gctgggaaaa
     3361 gaaaataatt gcaagagaat acatcgttgc ttcttttatc gaaatagaaa aaaacaccat
     3421 caataaagat acattgagcg gaccaccacc aatccctaaa aaactagaaa ttaagcccaa
     3481 tagaagacca caaatcatat agaatcctat cttatcaaat tgataagttt ttttaaaatc
     3541 tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa atcatttgaa caatggatac
     3601 taaccgtact gataactgag ataacaaaac ttgaaaaata agatgaccta gaaatcctcc
     3661 taaaatagaa gaaaaggata ccgtaaaaat caatctccat tttatctctt tactttgtga
     3721 aaatcttttg attgttgaaa taatcgccat tataaaaaca gagaaactag aataaaaagc
     3781 aatatcactg accgaatggt atccaaaact atccataagt ggcttaatta taattccacc
     3841 acccatgcct gatatagaac ccaatccact agctattata atgattagaa aataaataat
     3901 ctcaaccact ttttaagtcc atcctattct ttcaaacatc taaaacctag atggctacta
     3961 gtggaagtag aaatacatcc atttctagca gctactcggt atcgattaca ataagaacaa
     4021 tgacataaaa aggaacctcc tctgatagca tactcctcat cttgtatccc atattttggt
     4081 aactcatagt catcttcatt aaaactagct aataaggtat atctcggatt gcgacaccat
     4141 tcccaaacat tcccaatcat ttgatataga ccaaaatcat taggtaaaaa ttcatagaca
     4201 ggagccgttc ctataaatcc atctaaggca gtattttcat aaggaaatct tccttgccaa
     4261 gtattggcat gataatatcc accttctaaa agagtatctc cccaaggata ttcagattgt
     4321 cttcctcctc tagcagcata ttcccactgt gcttcagtcg gtaaagacat tccgctccaa
     4381 ttacagaaag ccaatgcatc ttctaaagca acatgaacta ctggatggtc ttctaaaccc
     4441 actagattac tgttctcacc gtagggatgt ttccagcaag cgttcgaaac ttgtaaccac
     4501 cacggagccc cagcaggatg aggatatccc tccctttctg cctccggaac gaacaatata
     4561 aaaacaaaag accactcttg tcgctcagct agtgttttat agcctgtttc tttcacaaat
     4621 tgagcaaatt cttgattcgt aactggagta tccgcaatgg aaaaatcctt tacactaaca
     4681 gcgacttgaa gaccttcaaa atcatctaaa aagccctctt cagaatttgt tcccatcata
     4741 aatgtcccac ccttgatttt tttcattttc atgattgact atcccccgtt ttcgttagag
     4801 ttggcgttat tttagaaagt tcaacaggaa ctaactcttc atccacaaca aaaccttctt
     4861 ctctatatct aagaaagtct actaattttt tcttcatctg acgaacaata ggttgatatt
     4921 tttcacttgg atacaaatca ttcatttcat gcggatcttt tttcatatca aataactgat
     4981 aatgatttaa aacaggaaac cagataaatt tccactggtc tgtcaaaata tattgactag
     5041 aatcttttcc taaagcatgt tcaccatgaa attctgttcg ccacccctcg tactgtccaa
     5101 ataataaatt cttaacactc cgtccatcta gttcatctgt agtagttcct cctgccaaat
     5161 ccacgagtga aggaaaaata tcttgaattt tcactaattg cttgattgtt cccctattac
     5221 cagctatcaa tccagctgga tcgtaaataa acgaaggaat gtggatactt ccctgataag
     5281 gatatccctt tctaaacaga taatgttcac caagctgatc tccatgatcc gaaacaaacc
     5341 agataatcgt atctttatca tgacgaaatt cttttagggc agtcaaaaag cgactaattt
     5401 gatggtctat atgagtaatc aatccaaaat aagcagcaac cattcttctt tgatcatctt
     5461 cctttaattt ccctcttaaa gcataaatag acggaatttg cttttctaat acttcccaat
     5521 tcccgatgtg caaatcgaga aattgaggca agcgttccat atacatatca aaatagtatt
     5581 ttgggggatt taatggagca tgtggttttt caaaagacat tttgagaaaa aaaggaaccg
     5641 ttggatctct tctttgtaaa aatgaaatgg actcactcac aacccagttt gttggatgta
     5701 acttctcatc tttatcccaa ggtctagctt cccaagaatt acaatccatt ccgtcatcaa
     5761 tcaaatcaac atcataacca actttaccct ttaaaaaggc tagatagtca ctagcataat
     5821 caaattgact tccataagcc ttatcatact ttctatcaac atgtagatac ccatcgtgaa
     5881 gtaagacatg atcaaaccca agtctctgtc tggaaggaaa aacatgcatc ttaccaatac
     5941 actctgtttg ataacccata tctttaaaga cttttggaag agtattagta aaattccaag
     6001 gcacctcatc ttgataacca actcgtccac ttttatcttg gtctaagcca gtcaataaag
     6061 ctgccctagc aggaacgcaa gaaggaactg gagaataggc attttcaaaa ttataaccta
     6121 cactagccat catatctaat gttggagtgc taactagctt atccttacta ttcaaggata
     6181 aggcgtctgc tctcatttga tctacaacaa tcaaaataat atttggctgt tttgtctgaa
     6241 ccataaaatc tcctttctaa tatggcaaaa gaggcacaag aagatatcta cctttactgc
     6301 acccctttct atatcaatct ctctatataa aacaataaca ttcttgttat gttttataga
     6361 aaaatgaact aaaatatgac taaatcgatt aggaaattca aatcattttc tagtactatt
     6421 ttagaagtta cagtgtacta ttccaacttc aataaactat aaacctttgt ctaataacaa
     6481 ttttagtgga gataagaaat cctacaccta actcaatctt acacgtaatc tatttctatt
     6541 ttatcacaaa aaacgcaagt aagaccatta actcaattca gttttatctg ccattttcac
     6601 aaatgggaaa taagtcaaga cactaataat caaacaaaca actgataaga tgatggcacg
     6661 ccaatcaaat gctgtagaga agcaaccata taaaattgga ggcattaccc aagtaacatt
     6721 ttgtgtaaca ggtgaaacaa gaccccagct tgttgcccag taagctaccg ttgccatgaa
     6781 aaccgggcta agtacaaatg gtataaatag caaaggattc aagacaactg gtaaaccata
     6841 atttaccggc tcaccaatat taaacagaac tggtgctaga ccaagtttag caacttttcg
     6901 ataatgactg tttcttgaaa aaattaaaat agcaagtacc aatcctaatc ctccaaacca
     6961 gacaaacgcc ccaaaagacc cacttgtcca tatataagga atcggttcac ctttttggaa
     7021 agcatccaga ttcgctaaca tagcaactcc aaacagccct tccatgatgg gagccaatac
     7081 atttcctcca tggagaccaa aaaaccagaa taacttattt aaaaagatca tcagaataac
     7141 tgcaaagaaa ctttgagaca aacctagtaa tggcgtttgt aacaccttgt aaacccaatc
     7201 aatcaataag tcattgctaa gtaaatggaa aacataagtc aagatggcta ctatatacat
     7261 cgccataaat cctggaatga tagaagtgaa cggcttagca atcgcagggg gaactgaatc
     7321 tggtaacttg attacccagt tctttttcat tactttacag aaaataatag aggctaaaaa
     7381 tccaatcatc atggctgtaa agtagcctct ggcattaata tggtttcctg gaatcacatt
     7441 cccaatagtt accatcagat ttttaccatc aaatgctaga ttatcaattc cttgtaagat
     7501 ttgatctaat ttcacatctc ctacatttgc caaagggaaa ctctttgtaa ctgtacttcc
     7561 aatcgaaatg acaaacgaag caagcgatac caaaccagca gaaactgtat caaccttata
     7621 aatcttagcg atattcactc ccaagcaata gatgaacaat aaggaaacaa ttggtatact
     7681 tcccttgaat accaaattat tgatgtcaac aagccactga aaggttttcg taatactttc
     7741 taggtgaaat tgttgtggta aatccactag aaaagcattt aataacaaag caatggaacc
     7801 tgtcataata acaggcatag tccccacaaa tgaatcacgt aaagcaacta aaaacttctg
     7861 attcccaact ttcattgcaa ttggagaaag tttttcttgc attttatcca acattgtatt
     7921 cataccaaac tcctaatttt tttcaaatcg ttcgtatact tctaccactt ctttcgccaa
     7981 gtcaacaaag gtcagactcg tcattaaatg atcttgcgcg tgtaccatca agaggctaat
     8041 tgatgtttct tccccctgtg cctcttttgt caacatttct gtttgagcct tatgcgcctg
     8101 taataaggca gcattcgcat cagctaatct tcgattggct ttagagaaat cccctttttt
     8161 tgctgcctga atagcctcca tagcattact tttggcttcc ccaccataca taattagccc
     8221 cattacagat tctaaattac tttcatccat aacattctcc tcaatcttag tctaataaac
     8281 tttcagctaa atctaagact ttagaaccat tcatcattcc ataatctgtc atcggaataa
     8341 ccgccacagg aatctgtcta tcttttagtt tttcttgaaa gtcccctagt aaatagcgaa
     8401 cttgagggcc taaaagcaac acatttactt cttttgttgc tacaatttct tctgcttcag
     8461 gagctggaac tgcaaaaatt tctgcatcca accccttatc ttctgctgcc ttttgcatct
     8521 ttgtcactag cagacttgta ctcatacctg ctgcacatgc taacataatt gttactttag
     8581 ccatagctta ctcctttatc acctatttac tgacctagcc aagcgagata ctgtatgtct
     8641 cactcctcta attgccttgc tcaatgcata aatattatcg actgttgcca gtcccccata
     8701 tcctgcgtca cctatatgtt gaatatcaac tccacaaatt ttatttctaa gtgcaatttc
     8761 cttgatagta tctgtatcag atgtttcttg gctagtacca atagcactca gtactagccc
     8821 acccttacta tgaacgagat caacgacttc acgcaactct tggtcatgaa aggctggaac
     8881 ggttccaact gctggaacaa gtatcacatc cgcacctgct tccaacaatt gctctgctac
     8941 agaaagctct gccacaggct cattcactcc tgccccgtgc atcttacctg caataatcaa
     9001 accagaaaag ttttccttag cagtttgaac agccttaatg atttctcgat tgctaactcc
     9061 tgttccagga tttccagtca aacagacaaa gtcaaaacct aactcctcta ttcgattcaa
     9121 tgtttcaaca ctagcaacac gacctgcaac aatttcctgt gtttcctcta gcatctttgc
     9181 agatgggtca atcggttcca aatttacacc aattggacaa gcaacaagct ggtgtaagcg
     9241 atgaataaca tcatcacctg aactatccaa agcataaatt ttaggctcaa aaacatcaac
     9301 acaattcaat aaaatcatat cagctccaaa agctctagca atttcagaat tagttatatc
     9361 cccaacaaat gtctcacgag taactacatt ttcagataga acaactctac cttcacttgc
     9421 taaaatactt tgttttaatt cttcagcatt catctgtaat atctcagatg gatttgcact
     9481 aattaaacgt ttcattctca atcctccaat aacttaaacc gtttttcaat agctattaca
     9541 aatggtaaat aaagtaagac atccaaaaca atcaatacaa tttgtaataa tgaaccagaa
     9601 atacttcctg tagcaagtaa accacttata acaggtggca tagcccaacc tggatctgta
     9661 taagttagcg gaaccaaacc tgatgccatt gctccccacg ctactagtaa gttaaacatt
     9721 ggagctaaga taaatggaac tagtaacaaa atgttcaaaa caataggaac accaaacatt
     9781 gctggttcat ttatattaaa taatccaggt ataacagtta taggtgccaa agtttttagt
     9841 tgtttactag ctttcttctt atgtgctaaa tatcctaacg caagaactaa acctatggtt
     9901 gcaccaccgc cacctatgaa tacaaaatta tccataaata cgctagtaaa aatatttgga
     9961 agagtttctc cagtttgata agctacttta tttgcatcta gattagctaa ccataacggt
    10021 ttcataactg cattaacaac atttcctccg tgtaatccta caaaccaaaa actactatta
    10081 aggaaaatta agataagaag accaataaca ttatttccta aaagtccaag tggacctccc
    10141 aaagctactt gagcaatttc atgaagatta ggtaaactta atttatctaa agttgcataa
    10201 acaatcaacc aaccaacaat agtcactgca ccaggaataa tggcactaaa gcttttagat
    10261 actgctggtg gaacaccatc cggcattttt atctgtatat tatgatttat aaaccattgg
    10321 tagatatagc cattaatcaa tcctaaaatc atagcaacaa ataaaccttt tgatgccatg
    10381 aaagcggtag gcattcctgc tccagcctct cctctaatga aagacgtaac tgtaataaaa
    10441 gatgataatg acacaatacc agcaggaata ccatcaactt tgtattgtct agccataaag
    10501 taagcgatac caaaactagc tacaagacca agtaatccaa aactactatc aacacccttc
    10561 cataaatagt cagcaacacc aatatcaccc agatattttt cccatcctgg aataggaaaa
    10621 cttgcaataa ccattagtaa tgaacctatc aacaataaag gtatagttag agtaataccg
    10681 tctcgaatag aaaccaacgc tttattatta cccaatctag ccgctactgg aagtaacttt
    10741 tcttgtaata atttttccat aaccttttcc tcttaaatat attttattat caaaagttat
    10801 caattatctt tattttttga cgtcaagttg ttatttgatt atcttttgtt atttatattt
    10861 tacaactata agaaagcctt gtcaaggatt tgtgtaaata tttgattatt ttttattatc
    10921 aatatataat aaaaagagac cagtaagtaa tgaaaagctt aaaaagatta acatctacat
    10981 ttatccatag caaaaaatca taggatttta agaatctgac aactaggaag aaaactaata
    11041 tgaccttatc taagaaacaa ttacaactaa gagctaaaat actggaaaca gtttacacat
    11101 taggtcccat ttcacgaatt gaaatcgcta ctaaaacagg aataacacct gcaacaacta
    11161 gcagtatcac aaatgatctg attaaagaaa atattctctt agaacttggt gaagacgaac
    11221 acgatacaag cgtaggaaga aaaaaaatcc tgctagacat tcaagctaaa cgattttact
    11281 acattggttg tgaactatct gaaaaacatt tcacttttgc tttaggagat aatctaggaa
    11341 atatcttaaa ggaagagaaa gaaattgtta ctaaacagtt aatccaagaa aagggaaatc
    11401 aactcattaa ccagacacta aagcaattct taaataactg ctctgattat gaaatagaag
    11461 caattggaat cgcgctacct ggtcgctatt tagatgatta taaaataaca acaaacaatc
    11521 ctttatggca acatatcgac ttagaaatga ttcaatccca ctttgataag cctttgtttt
    11581 tctctaacaa tgttaactgt atggctatag gtaaacgcct atttagtcgc caacagaatg
    11641 accctaattt tgcttatttt cattttgcta gaggtatgca ctgttcttat atctacgacg
    11701 gaaacattta tgggaaagga aatctaatga ttggagaaat agggcataca gttgtttcat
    11761 ctgagggaga agaatgtagc tgcgggcgca agggatgctt acaaactttt gctggagaat
    11821 cttggttaat caaaaaatca aaaattctat atcatcaatc tccctattct ctacttccta
    11881 gtttagtcaa aaatgccgat gatattgata tccaagttat tttaaccgct tatcaattag
    11941 gtgacactgg aataatcaca cttatccatc aagccttact ctatcttagt caaaccattt
    12001 taaatatcag tatgatgatt gactctcaaa aaatctacct acatagtcct ttactaacaa
    12061 atcaacacat catccaaaaa ctatatagtg aaatgaacta caaacccaaa ctgctctata
    12121 atcgcctacc tgaagtcatt attgaacctt acaatgattt tacagccgca cactcagcta
    12181 ttgcactttg tttgtatcat acaattctac attcttaatt ttctattaca tttaataaat
    12241 aggctaaaaa gagggagtat atcataaaaa gcgaataaac ctgttttctg aaaatcagaa
    12301 ttctgttttg ttcgctttct ttatatttgg aattatactc ctatctcccc tttttcataa
    12361 tgtataataa aatgaaataa taacaggacg aatcgatcgg gacagtcaaa tcgatttcta
    12421 acaatttttt agaagtagag gtgtactatt ctagtttcaa tctactatat tttcgtacag
    12481 gtgcttcaac catttgaacg atttcaaatc cttctttttg gtaaagattc tgaactcttt
    12541 gatttgcctc gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac
    12601 taacaaattt ccttaaagcc tggctaccta agtcttgctc ctgtttctgg gggttgataa
    12661 aaaatctccc gatatgaaga ttgctgtctt ctagcctgat tttctggata aatcccacaa
    12721 actcttgttc atcaaagatt gaaaagactc cttccaaggc ttgaagggtc agtagaaaag
    12781 gaatccttgg tcccatccat tgttcttgaa aggatttgcc tagggagttg gaccactggc
    12841 atacaaattg agcgttttct gtgctcacct tttcttcaaa acgaattgtc atcttttcct
    12901 caccacctta tctatgtttc tccattatac tatttctccc attttttacg aatagataag
    12961 tatgattgat ttttattttt ttctcgtcgg gagcattcta gcttcctttc ttggtttggt
    13021 cattgaccgt tttccagagc aatccattat cagttcagcc agtcactgcg attcctgtca
    13081 gactcgcttg cgtcccttag atttgattcc gattctctca caggtcttca atcgcttttg
    13141 ctgtcgctac tgcaaggtcc gctatcctgt ctggtatgcc ctctttgaac taggcttagg
    13201 actcctcttt ctgctttact cttgggaatt actttccttg agtaaagtca tcctaatcac
    13261 tgctggtttg accttgggca tctacgactt tcgccatcag gaatatccct tactggtctg
    13321 gatgactttc cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt
    13381 cctcatactt ggaattttgg ctcattttat cgatatccgc atgggtgcag gggatttcct
    13441 ttttttagct tcttgcgctc tcgtctttag cgtaacggag ttactgatct tgattcagtt
    13501 cgcttctgcg acgggtatcc tggcctttct cctgcaaaag aaaaaggaaa gacttccttt
    13561 cgtgcctttc ctcttacttg ctgcttgtgt gattattttt ggtaagctac tgcttgtttg
    13621 ataaattcca atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat
    13681 tatttctttt gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat
    13741 actgatcaaa aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac
    13801 tttgtttaga cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa
    13861 tactctttac tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt
    13921 tgtaaccttt ttgcgcaatt tgacgataaa agtaagaatg ttgctttgga gtcaataatc
    13981 ctaacttaaa agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata
    14041 aaatataact atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa
    14101 actcttcttt tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat
    14161 cgccatcttc attcatatct ttatatttat gtaaaagaat atgtcctagc tcatgagcta
    14221 agtcaaaatt tcgacgtaca gatgatttat tcgttcccaa cacaatataa ggtcttccca
    14281 attttgacca tgcgctataa gcatcagctt ggtcattaat taatcgttcc acgatataga
    14341 tgcctgaacg ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt
    14401 ccctggcata aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta
    14461 cattacttag gtcatgaatt gtaatattag gtataattac aaaactttca aaataatcaa
    14521 tcaaactatc taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta
    14581 ggtctgcatt tctaaaggca attacagaag aatcaaatcg aatgctctct tcttcctgtt
    14641 caaaataagt taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag
    14701 gtttcgtttc gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag
    14761 ctaattctgc tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa
    14821 acatttacat actccttact acttttgacc ttcttgtttt tctattcttg gaataatttc
    14881 aaaatcttct gtttccgata attctgaaaa attaggaata tcttgatatt tagcttcttc
    14941 gaaatggtac gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc
    15001 agttcgtgca tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc
    15061 ataagttaaa atcataaatt tttcgatatt cgaattttta gtagcttgtt caatttcttg
    15121 aatcatttca tcagaaacta actccatctg aattggaaag gaatgactat tttcatcatt
    15181 tttgtaggaa gaatgttgat taagataaag tgtattcatc tgagcatatt caaataagta
    15241 gccactctta tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat
    15301 aattaacaat actttcccat atttttctgt atttgtttca aattctaaat atccccaagt
    15361 ctgtcctgct aattgtaatt tatactcaaa caaatctgct gatgcaaatg cagtatcaat
    15421 atgattaggt cgcgtccatg cataaccatt cgacactatc attgtctctc ttttttctag
    15481 acgttcatct acataatctt tttgcccttt catcaaagta tctacaattt tttgtgcctc
    15541 aagcgaatca aagagatcct gattcaacat aattcttcct cctccaaata ctttttaatg
    15601 aattatatca ttttcttaaa gaaattacta caataattat ctttttctta aagttctgtg
    15661 tcagagtaat ttagaaaatt atatcttcta tagtaaaatc aattaaaaac tgaacaaatt
    15721 tattgggaaa ttcaaatcac tttctgaaaa tattttagga accgtagtgt aatattccag
    15781 attcaattca ctataaaact agcctttctc ctgcaaaaga aaaaggaaag acttcctttc
    15841 gtgcctttcc tcttacttgc tacttgtttg attatttttg gtaagctact gcttgtctga
    15901 taaaatcctg aatcggctct ccttggtgga gagcttttac tatttttgaa ccgacgataa
    15961 caccatctga caccgcattg aagcgttcca gatcggcttg actagataca ccaaaacctg
    16021 tcaagactgg gatgtcggcc acttgatgaa gttgcgccaa gtgcttgtcc aaatctgcac
    16081 ggtaattgcc tgatttccct gttaccccat tgatggcaac ggcatagacg aatccctccg
    16141 ccccttcaat caactctttc tggcgctcaa ttcctgtggt caagcttact aaaggaatca
    16201 aggcgatatc tgtatctgcc aaaaatggtt ctacaaagtt ggcatgttca tgaggcaagt
    16261 ctgggataat caagcccttc acagctgtat cagccagatc tttgacaaag ttctccacac
    16321 cgtactggaa gagggggttg aagtaggtca tgatgaccag tggaatctct gtttcaatgg
    16381 ttttcaaggt ttcaactaaa gcctgggtag aggtcccgtg ggctaaactg cgcaagccag
    16441 cttcttcgat aacaggtcca tctgcaacag ggtctgaaaa gggaatcccc acttcaatag
    16501 cagagacacc caaatcttct aaaaagtgaa ttgtttcagc aagaccgtcc aaaccttttt
    16561 cgtggtcacc agccatgata taaggaacga aaattccttt tccagttact tttatagcat
    16621 tcaatttttc tgttagtgtc ttaggcatga gcttctccct tctttgctgc atctgcttcc
    16681 aagcggtctt tgacttgaac cacatccttg tccccacgac ctgataggca gacaatcata
    16741 gacttttctg gtccaagttc tttggccaat ttcaccgcaa aagcgatagc atggctagat
    16801 tccaaagctg ggataatccc ttccacacga gacaagagtt gaaatccttc caaggcttct
    16861 tcgtctgtca cagggacata gctggcacgt ttaatatcgt ggtagtgaga atgctctgga
    16921 ccgataccag gatagtccaa acctgctgag atagagaagg cttcaagaat ttgaccatgg
    16981 gcatcttgga gcacatccat aagggaaccg tgaaggacac ctggacgacc cttggtcaag
    17041 gtagcagcgt ggtgctctgt atccacacca agccctgctg cttcagctcc atacatagct
    17101 actgactcat cttctacaaa gggatggaag agcccgatag cattcgaccc accaccaaca
    17161 caggctacta gggcatctgg cagatctcga cctgtcaagt cacggtactg ttgtttagct
    17221 tctcgaccaa taacactttg gaagtcacga acgatttctg ggaatggatg aggacccaag
    17281 gcagaaccaa ggatatagtg ggtatcatcg atattagcca cccatgaacg aagggctgca
    17341 ttgaccgcat ccttgagcac gcgcgaacca tctgtcacgg cctcgacctt ggctcccaaa
    17401 agctccatgc ggaagacatt gagggcttgg cgtttgacat cttcctcacc catgtagatg
    17461 gtacattcca tgttaaagag ggctgcagca gttgcagttg ccacaccgtg ctgaccagca
    17521 cccgtttctg cgataatttt ctttttaccc atgcgtttgg caagccaaac ttgtcctaag
    17581 gcattgttaa tcttgtgggc tcctgtatgg ttaaggtctt cccgtttgag ataaatcttg
    17641 gctccgccaa tatgctgggt caagtttttt gcgtaataaa gaggagtttc acgtcctacg
    17701 tactggcgca aaagctggtt taattcctct tggaaacttg ggtctgcctg actttcacgg
    17761 taggccttct ccaactccaa aactgctgtc atcaatgttt ctgggacaaa acgtccgccg
    17821 aattttccgt aaaatccatc tttatttggt tcctgatatg ccatgcttta ccctctctat
    17881 aaatcttcta atcttttcat gatctttttg tccatctgtc tccactccgc tcgatacatc
    17941 tactgcatag ggagtaaagt gttgaattgc ttttactaca ttatcttcat taaggccacc
    18001 tgcgataaag aagggctgtg ctagtccagt cgtatccagt tgaccccaat caaagggctg
    18061 gccacttcct gccacagggg catcaaagag tagataatct gcctgagaat tggggacatg
    18121 cccatttcca tctacctgca cagcctgaat actggcacaa ggcaaattct caaataaatc
    18181 atctgccacc tgaccgtgaa cttgaaccaa gtccaagcca actttgtcaa tcgcttccag
    18241 cagttctacc cgacttggtg aaacaaatac tccaaccttt ttcacatctg caggaataag
    18301 ctttgccaac tcagctgcct cttctaaagt cacctgtctt ttactaggtg caaagacaaa
    18361 accgatatag tcggctcctg ctgaaacggc tgtttccacc gcttctttgg tcgatagtcc
    18421 acaaatttta acctttgtca atctgcaact ccttgattct ctgggccaca ttttctgcct
    18481 gcataagagc tgtccctacc aaaattccgt taaagtatgg ggctagtcgt tccgcatcct
    18541 gccctgtgaa aatggcagat tcagaaatgt aatagcgacc ttcctcaaag taaggggcta
    18601 aatctacact ggtctgcaag tcgacctcaa aggtagtcaa gttgcggttg ttgaccccga
    18661 taatctcagc accaagtctg tgggctacct ctagttcagc tagattgtga gtctccacta
    18721 agacttccag accaagctct gtcgcgtagt catacagttc cttgaggcgt tcttcggaca
    18781 aggctgccac aatgagcaag ataactgtcg cacctgcatt gcgagcgcgg atgatttgct
    18841 tttcatcgat gataaagtct ttgttgagcg tcggaatctc tacctgactg gaaatttccc
    18901 gtagataatc caaatgccct ttaaagaaaa cctcatctgt caacaccgaa atcatcactg
    18961 ctccgttttc ttcataagtc tgggcctgtt gcacaatatc cacatcgaga ttgatatctc
    19021 ccaaactagg gctagctttc ttgacctcag cgattacctg caagcggtcc tgatgattct
    19081 tcaaaaattc tgccaagcga taggtctggc gcagaggctg gatttgctcc agcttcatct
    19141 gctccacctc acgcgccttc tgctctaaga ttcgtgctaa aaattcctga ctcatttttg
    19201 gtactcctgt aacagtctga gtttttcaag ggccttgcct ctagcaatca cttgacgggc
    19261 caaggcaacc ccttccttga tgctatcaat cttaccatta gcatagaaac caagaccagc
    19321 attcaagact gtcgtttcca agaatggact tgcttcgttt ttcagaacgc taagcaaaat
    19381 ttctgcattt tcctgagcat tcccaccacg aatatcttcc atagcatagc cttccattcc
    19441 caaatcctct ggagtaaagc ttgacaagct gatttcgcca ttttcaagaa gtgcaatctt
    19501 ggttgttccg ttcaagccag cttcatccaa cccttctggt ccagcaacca cgatggcacg
    19561 tttgcgaccc atatttttca aaacctgagc tgtactttct aggagttctg gacgactaat
    19621 tccaagaagc tgtgtttcta aagccattgg atgaatcagt ggaccagtca agttcataat
    19681 cgttggaatt cccaattcca aacgagctgg catgatgtat ttcatagctg ggtgcatatt
    19741 tttagcgaag agaaagacga ttccagtttt atcaaagacc ttacctagtt cagctggttt
    19801 gaggtcaaga ttgattccca aggcttcgag gacatctgcg gaaccagatt tagaagaaat
    19861 cgagcggtta ccatgcttgg ccatgtgaat accgccacca gccaagacaa aggctgcagt
    19921 tgtggaaata ttaaaactga aagacttgtc cccacctgta ccacagttgt ccatggcatc
    19981 atgaatctca gttggaatat gctgggcatg tcctctcatg acttgggcaa tggctgtgcg
    20041 ttcttcaggt gtttccccct tcatcttaag agctaagagg agagaagcaa tctgcgcttc
    20101 agttacacgc ccagttacga tacgctcaat gacatccgtc atttccacac ctgataaatt
    20161 ttcaaatttt gctagttttt caataatctc tttcatccta gtttcctcac tttacaacct
    20221 tctcgataaa attccgaata gaagacaagc cgtctggcgt tccaatgctc tctggatggt
    20281 actggaagcc ataaatcggt aggtttttat gttgaatccc catgatggct tggtcatcag
    20341 tcgaacgagc tgtcacttca aagtcttctg gcatttcctc aatcaaaata ctgtgataac
    20401 gcatgaccgc acgtccttcc tcaatacctt gatacaaaac agatggcgct tcaaagttga
    20461 tattgctctg tttcccatgc atgacttttg gagccaaacc tagcttacca ccaaagactt
    20521 ctgcaatggc ttggtggccc aaacaaatcc ctagaatcgg cttcttgcct gcaaaatcac
    20581 gaatcatgtc ttccatcttt ccagcatcaa ctggccaacc aggaccagga gaaaagacca
    20641 gaccatctgc tttttcagct tcttcataca gcttggaatc atcatttctc agaacctgaa
    20701 cttctgcaaa attcccaatg tattgggcca agttataggt aaaagaatca tagttgtcaa
    20761 tcaataaaat catggtctta gttctccaat tctagtcata gattttgctt tgttaatggt
    20821 ttcttggtat tcgttttggg cgatagagtc gtagacaatc cctgccccag cctgcacata
    20881 ggctctttga tttttgagaa tcatggttcg gatggcaatg gccaaatcca tatcacccgt
    20941 cgcagacaag tagccgattg ctcctgcata tacgccccgt ttttccgttt ccagttcata
    21001 gatgcgtctc atcgcccgaa tctttggtgc tccagaaacg gttccagcag gaagtgtagc
    21061 tttcaaggca tccatggccg tgagttctgg aagcaaacgc cccttgacca cgctggtcaa
    21121 atgcatgacg tagcggaaga gctccacctt catatactta gtaacttgga cactggccgt
    21181 ttcagagatg cggccaatat cgttacgccc caagtctacc aacattcgat gttctgctgt
    21241 ttccttctca tcagagagga ggtcagtcgc caaggtcttg tcttcttcat ccgtagcccc
    21301 tcttggtcgc gtccctgcaa tcggattggt tgtcacgatg ccatttttga cagaaactaa
    21361 actttctgga ctagctccga tgatttgata atccccaaaa tcatagaaat aaaggtaatt
    21421 agaaggatta gtcacgcgga gatttctgta gaagtcaaat ggatttccag taacttctgc
    21481 tgagaaacgc tggctgagta cacattggaa catatctccg ttacgaatca agtcacgagc
    21541 tgtttctacc attccctcaa acttatgtgg agcgatatgc ggtttgaagt ctaacggaga
    21601 tagatccaaa tcttcaaatt catttggagc aggaatgcgt aattcctcaa gcacttggtt
    21661 caaggatttt tccaaggcct cttgactgcg ctcactataa agtgcatcct ctatgacatg
    21721 tatcttctcc ttcttgtggt caaagaccat atagctctca tagacaaaga aatgcatgtc
    21781 tggcgtccca attgtatcct cagggatttg accaatttct tcataaagcg aaatcatatc
    21841 gtaacccaca aaaccaatgg ctccaccacc aaaaggtagc tctgagtggt gctgactctt
    21901 atgaatcact tcataaagga aatccaaggg atcccgatca atcacttgac cattttgata
    21961 gagaacccca ttttcaaact taatctcaaa aactggatta taggctagga tagaaaaacg
    22021 agctgtttcc ttgtctctcg gaatactctc taaaataacc ttatgttgcc cctttaagcg
    22081 catataagcc aagattggtg ataagacatc tccatgaatg attcgttcca ttgtaatttc
    22141 cctttcagtt ctacttctag tccgtggtga ctgtatgaaa aatccccacg caaaataact
    22201 tgcgtgagga cgaaattcgc ggtgccacct caattatagg atttctccta tctctcattc
    22261 ctgtctcaga tatctcctgt aacaggctgt gcgataaagg gcactccctt gagaatgatg
    22321 ttttcttctc tcgtttcaga tgaacccaac tttacagctt tctctgcttg ttttcagcaa
    22381 ccacaagctc tctgtgagag aaagaactgt aatttttcca tctattattt tttagcttct
    22441 agtaatctgc aatcgcagct aggtccttgc ctccacgacc agagacattg atgaagagat
    22501 gttcatctcg gtacaccttt atactcttcg aaaatctctt caaaccgcgt caacgtcgcc
    22561 ttatcgtagg tatggttact gacttcgtca gttctatctg caacctcaaa acagtgtttt
    22621 gagctgactt cgtcagttct atctgcaacc tcaaaacagt gttttgagct gacttcgtca
    22681 gttctatcca caacctcaaa acagtgtttt gagctgactt cgtcagttct atccacaacc
    22741 tcaaaacagt gttttgagct gacttcgtca gttctatcca caacctcaaa acagtgtttt
    22801 gagcagcctg cggctagttt cctagtttgc tctttgattt tcattgagta ttactagctt
    22861 ttttcgtatt agtccagcct ttttgtttgc ttttagtagt aggcaaggag ctgtagatag
    22921 aactcaagtt catcaaagcg acttaaggcc ctaataaaag ataaaccaaa cgacggatag
    22981 aaaaaagccc acacacagaa tatacttccg tgtgagggcg ttggtaacgc ggtgccacct
    23041 caattataaa gggactatcc ctttacatct ctgccttgtt taacaacaag ctgcactgta
    23101 aggtgtgcgc accgaatttt cattgtttca aattcatttt caaaatcagc ccactttcac
    23161 tacttccaac cacctattca caaccaccac aggctccctg aagatcaaaa atagttactt
    23221 ttctgatttg ttgaacttat tttaatactt tgttttttct ttgtcaagac ttttttacga
    23281 tttttttgaa aatatcattc gaatgtgacc atgtcttcct tagatcgaac atgaacatgt
    23341 cccacttgtt agaaattgga tccaactcaa tagaaactga atggaggcta aacagaactt
    23401 attttagaac actccatctt ttccactagg attttcaaga attaaacaat actagaaact
    23461 ctgtctccta acaaatttag gagaaacttc aacagatgtg acactttccc ctttaataat
    23521 tgctaaaaca ccttctatca tttctttagc caatttaaca taattgggag caattgtaga
    23581 caaagctgga gtataatact gagaaatagg aatattatca aatccaataa tagaaatatc
    23641 atctggaata agaattcctt tctcatagca cgcacgaatc aagccctgaa ccttttcatc
    23701 tcctgaaaca aaaataatgt ccggataatt ttgggtagtc aagtgctgca ttgcataaga
    23761 ataaactgaa tcaattgtag ataagccata aatgactttt aaatccataa agtaattttt
    23821 atcattcaga aaagaacgca cacctctttc acgatcctta ttaacatgag attctcctcc
    23881 cataagcaac cacatatttt taaatttttc ttcagttaca gctttcatca tatcataagt
    23941 agcttgaaaa ttattattag atacatagac tactccagac gtttgagatt caccgaaaac
    24001 aagaaaaggc atatggttct tctttaaata ctgaattctg atatcatcta cactttcata
    24061 aaaaacaata acaccatcta ctaggctacc tgtgcttgat ataattgaat tactaattgt
    24121 atcctcctct ccaaagtact caactatagc attaacacca aattctttac acgtccgtaa
    24181 cactttatct aacagcgtat gaaaccaaat taaaggaaaa gagtcgattt tttttacaga
    24241 aatcaatata tttatagctt cttttttagt taaatttttt gcatacgcat ttggaatata
    24301 cgacaattcc tctataactt tttgaatcgc ttgataagtt tcttctttaa catttactcc
    24361 accattaata actcgtgaaa ctgtttttgg agaaaaacct gataaacgtg caatatcata
    24421 aatagttacc tttttcccat ttatattttt catttcagtc ctccattacg aacattctaa
    24481 tattactata caatatttaa ttttttttaa caagagaatt tagtaaatta tttaagatcc
    24541 acaaattcac aaaattaatt ttacaaatat tcttcccctt caaaaaagtt taaattgcat
    24601 ttcacacctt tatttttaag aatgtttcca acttcacgac aaataaattc atatgagaaa
    24661 aaactaccat aaaattgtag attaactttt tcagtaaaat gtgtaggatt tataaaaaca
    24721 tataatagcc tgtcaatgta acattttaac atagagttaa ttttttcttt aaagataaca
    24781 tttgttatca actcatcagg aggtaaatga aaggcaaaca ccatttcata aatatcataa
    24841 aaagaaataa atttgtata
//
LOCUS       DAVHSH010000022        24208 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000022 DAVHSH010000000
VERSION     DAVHSH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.022"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..153
                     /locus_tag="VVR08_001107"
     CDS             <1..153
                     /locus_tag="VVR08_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6075033.1"
                     /translation="FAGEFHYPSELNRLYQKIRHYKMEQRMPQSPWVERIVQVLDLDY
                     EDLFRR"
     gene            156..743
                     /locus_tag="VVR08_001108"
     CDS             156..743
                     /locus_tag="VVR08_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075034.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYSSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGLVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            1033..1668
                     /locus_tag="VVR08_001109"
     CDS             1033..1668
                     /locus_tag="VVR08_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075035.1"
                     /translation="MTYTLEWLKTFDGEIDILNIKMNCLANTIEKNVSQYKYIYQTNM
                     ENCPEIILSVPNSSIPHLLGLSREHHVNLPTNNAGSIFEGLKDDWTLESLNKADNGWF
                     NENKFKIVGTLLLYQMLHVMECKFYTTDGILNRRVGSRFRRDNIYFVVFKLSNGISYT
                     VELSREQGNQYFPRSLKINDTSVTDCREIDLRLINKIRFKPVKARKVKWPS"
     gene            2022..2517
                     /locus_tag="VVR08_001110"
                     /pseudo
     CDS             2022..2517
                     /locus_tag="VVR08_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
     gene            2771..3067
                     /locus_tag="VVR08_001111"
     CDS             2771..3067
                     /locus_tag="VVR08_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6075036.1"
                     /translation="MKTSKIILSVLTVIISCSLACPVFADWVSGGNWSYGGYHNPGNW
                     GAFSNYFHDYRWHWSSVTRASDSKANVGYASAHYTSRSFINTSFGETAYFNYGF"
     gene            3129..5138
                     /locus_tag="VVR08_001112"
     CDS             3129..5138
                     /locus_tag="VVR08_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEU6075037.1"
                     /translation="MKRLFIHFSNLFILIFLLWIAFISPNTVIHRSLPVIGILQQERE
                     VVYEELSSSLDQLAKENNSLIARQIQKTDSKGQVKFSYDIYGEGALPNGIKKEEKEFV
                     AKESLLTNYYILSGNLTLEKLDQKLHDLGFSKSFMNKPNPLQNFMVFFSSGSQSLALV
                     IFIISFAALTIIQKTLEMRSAGIRYISGIRRYQLFGHSLMEDGKELFLGCIGGSVLGA
                     ILIYYLQLTPFAYSLIISASIIYNTLLFILSAFLSFFFAFSIQTVHLVSLLKGKIPLK
                     RVLFFLFTCQFLAITVIGLSIHRVSIYGSIWQTYQEGSLAWSKETNWIQISLNRENVL
                     QTTNKEMQIEQIAKWSKLIESGIEKGGLLVHHQLAAFNSKGFMNDPRTGRELSITDYD
                     PLANTLYVTPNYLDIQRILVSPEEKERLNHLQAGEFGLLLPEKLKGQEEELKKRYEDY
                     LTPSDEQGKSQLPMKARVTYLPNNQKRFIYNNTPMIYQQFLTDPILVVVLPRSFGGYD
                     NPYFSHLNSYLYFDGLEKSKKLVVENGLEKNVSQYDYAASVYQQMIQSIQLENLITIA
                     GGIFAIATSILLFNTMNFLYFEEFRRPIFLKKIAGLGFVKIHQMILLSESILLLLGSF
                     LTFLLTQEWWIALVTLLLFITNAWFILLYRSHKEDHLLATVLKGA"
     gene            5140..5772
                     /locus_tag="VVR08_001113"
     CDS             5140..5772
                     /locus_tag="VVR08_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bacteriocin export ABC transporter"
                     /protein_id="HEU6075038.1"
                     /translation="MISIEHLTKSFGQRTVFQDLSLQFTEGKVYALIGNSGCGKTTLL
                     NILAKLEPYEKGSISYQGQELKQIKQHHFFKHELGYLFQNFGLLENETIATNLDLGLI
                     GQKLTKKEKKQQEEEVLKKVGLAYLALDQKIFELSGGEAQRVALAKVILKDPPLILAD
                     ELTAALDPETSQEVMDLLLMLKNQERIIIIATHNPDIWNQADEVINLNQL"
     gene            6366..6665
                     /locus_tag="VVR08_001114"
     CDS             6366..6665
                     /locus_tag="VVR08_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075039.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKRDYIEFKR
                     VGIFDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            6655..7143
                     /locus_tag="VVR08_001115"
     CDS             6655..7143
                     /locus_tag="VVR08_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075040.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFIMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            7143..9020
                     /locus_tag="VVR08_001116"
     CDS             7143..9020
                     /locus_tag="VVR08_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU6075041.1"
                     /translation="MYSGKKFILFSLLGILLGYLFHRLTLLYDSYTGNTLDKWIHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFLHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYKNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWRYLANQESDERWWNYQINPLNQNQENHLEGLRIRDLTFESSL
                     K"
     gene            9041..9283
                     /locus_tag="VVR08_001117"
     CDS             9041..9283
                     /locus_tag="VVR08_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075042.1"
                     /translation="MFTHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            9300..10154
                     /locus_tag="VVR08_001118"
     CDS             9300..10154
                     /locus_tag="VVR08_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU6075043.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSNYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGLGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            10208..10567
                     /locus_tag="VVR08_001119"
     CDS             10208..10567
                     /locus_tag="VVR08_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU6075044.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLLLFGVYKPNDLYFEHYLKYRLHFELTIPLRTISGKKGL
                     EHEKKIKYIKETKDFND"
     gene            10518..12875
                     /locus_tag="VVR08_001120"
     CDS             10518..12875
                     /locus_tag="VVR08_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6075045.1"
                     /translation="MKRKSNTLKKQKTSTTNKKEEVKDKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRHSVLYEEKEDGYDSYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFGSLTGEERVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNIAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            12887..15700
                     /locus_tag="VVR08_001121"
     CDS             12887..15700
                     /locus_tag="VVR08_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6075046.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKNEIKQKLENMREASKARVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFKEAKVEAKEERKESRKERKTNQKFFYGQETKVKSNFFLQGKNLEELKAKKE
                     VKAAKENLKSTKQAYKFKKISRKAKTFLYVLGREGGELASENEDLESYRTLHETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLTKDNPSSFKNR
                     YRKLKKQGLLSVRNIYQKLKGAFSFFTFVAGNPVIWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSALWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDGVVSL
                     DGDDVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYARTQNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYEHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISHADSAISFAYTTK"
     gene            complement(15731..15919)
                     /locus_tag="VVR08_001122"
     CDS             complement(15731..15919)
                     /locus_tag="VVR08_001122"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075047.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALTSK
                     ITIRLTMSRPLIYTIYFT"
     gene            15939..16505
                     /locus_tag="VVR08_001123"
     CDS             15939..16505
                     /locus_tag="VVR08_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075048.1"
                     /translation="MANSRDYRNPNYTETIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYRKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIGELLGKHVHLTGSGRYLYLEFDYALRTRKQIIALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            16657..17067
                     /locus_tag="VVR08_001124"
     CDS             16657..17067
                     /locus_tag="VVR08_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HEU6075049.1"
                     /translation="MEAIYQRDSDQDGLTDAQELALGTNPLSSDSDGDGRSDLVEIEE
                     GTNPLEKDLQDIDQTSITESSSVFMEMKQKISDMMESHYKEFILALISIETGIENQQD
                     LEDLYTYYMRMDAVSLLSSDLETSPQEVEMEIEL"
     gene            17115..23339
                     /locus_tag="VVR08_001125"
     CDS             17115..23339
                     /locus_tag="VVR08_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6075050.1"
                     /translation="MEVIQLLAMFRGTIPKDRDKMDLFLRYQAQHFDEKWQDLVESFL
                     TEEEKIEEIPHVYSFHQDIVSFLEASSENNDQDLESYTRNFGQAGLDKLSQLSNFEKN
                     LVLKVASYNLSTRFYIQSEKEKLTPLSELVFHQNQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKEVKKEVPEIHFEEKEGDVLAYLGSELMATLDIVTDLVHHEENYIQLPLT
                     QKLKIITHFDEVKAKSEKSNQVEKILSPSSDIEQETEETNSFSNVDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFNDSNQLFEENPILYLNSLEEIEQVLSHL
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENVNEKDKDKETKSLISGIEETDVPVLDFV
                     FPDDLEDFYPKTNREKIETNIAAIELVKRLEKERRQANPEEQELLAKYVGWGGLANEF
                     FDELNPKYETERLTLKSLVSKSEYSTIKQSSLTAYYTDPMIIRQIWQKLLDDGFEGGR
                     ILDPSMGTGNFFAAMPRSIREKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVPYQ
                     NNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTMDK
                     RTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVFSG
                     SVPFEEDKRVWINPYFDGKYNTQVLGEYEVRNFNGGTLNVKGESETLATDIMKALENV
                     EAPKQIDNSLKAPVFIQEEVDNSIPSHIRENLALYSFGYEGNQIYYRDTHGIRRSSKV
                     DEISYYVDEKGDFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGLFK
                     KTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRTDFQVLLSKLNRDYDRF
                     VSQFGYLNVSVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPERV
                     ITRVSTALDALNSSLSDGRGVDIDFMVSIYPEHSQAAILDELGDQILMDPESYLRGER
                     NYLSKNQFLSGDILNKIEVVQLLVEENNQECDWTHALDLLESVRPPRIHLADIEFKIG
                     SRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTPFAYRYPSAKDS
                     SLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHLQE
                     LFQDFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAIQR
                     IVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKFFP
                     TKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDKLN
                     ELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEAHH
                     FKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSISEL
                     YTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLPEL
                     MKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVDPS
                     QDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMENKATQMIFS
                     DIGTPKKKDNGFDVYSEIKALLVDRGIPSMEIAFVHDANSDEKKNSLSRKVNAGEVRV
                     LLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYITK
                     GSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKYKM
                     ELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEMSKDQS
                     FSMTIGKQVFEQRAEAGESLHRLIRHNQSDSKEFRTLASYRGFDIKMLSLATNQPLPE
                     TFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKDDQVKTQNLLDELKDKWTTAKV
                     EIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFELD
                     "
     gene            23414..23698
                     /locus_tag="VVR08_001126"
     CDS             23414..23698
                     /locus_tag="VVR08_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075051.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEIALQNHQGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            23712..24008
                     /locus_tag="VVR08_001127"
     CDS             23712..24008
                     /locus_tag="VVR08_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075052.1"
                     /translation="MNDLLLIPVIFLAVGGIIILLWRLFLIASGLFLIGFVSFLIFVE
                     VYGIYLFFTEPSLYFDDIRQYGLTSFTAVYLFINLMLVLGFSWRFINSINKHKM"
BASE COUNT         8091 a         3859 c         4919 g         7339 t
ORIGIN      
        1 tttgcgggag agtttcacta tccaagtgaa ttgaatcgtt tgtatcaaaa gattcgtcac
       61 tacaagatgg aacaacgaat gcctcaaagt ccatgggtag aaaggattgt gcaggtatta
      121 gatttagatt atgaagattt atttcggagg taactatgaa aagaataatt ccagtttata
      181 tattccaaca agtaaatgtc ctattggtat ctctatactt attgaaattt ctttgtatcg
      241 gtgagttaac tatactacag attctctata gttcgtcact catttctttt ttatggatgt
      301 atggtcaacg caaacaagct cataaggtca atatgaaatc taggatgaaa tggcttggta
      361 ttggattcgt tagcctactg attataagtc tatgttttag cctaatccat gctcaaggaa
      421 ctacgaatca agcaaactta attggccttc aacatcaagt cccttggttt tcatttttat
      481 tgttcttaat caatgcgagt atggttgaag aatttctgta tcgagaaatt ttatggaact
      541 tggttagaaa attagatatt cgagttgctt tgacaagtgt tttatttgcc ttagcacatc
      601 atccaggaac cattctagct tggtgtttat atgtttcact tgggatgttt ttagggcttg
      661 tacgctacaa atcggactta tggggcagta tggggctaca tttggtgtgg aacctactag
      721 tttatagttt gctgcttttt taaaataggt gacctgattt ttagatattc ataatgaatg
      781 taattgttga caaatatgga ctaattgcgt ataatgaaga taattaaatg atataattac
      841 ttgtgggcta gtggatatgg tctgcacccg cctgtgggct ccgctctcag ttcagactgt
      901 ttgttgagaa aaagaatagc aggactgcct acccttgagg aatagatagg gcatatctag
      961 cgtgaggtga aactcaatac gtgggagaga aggaagcagg agcttccttc tcttttttag
     1021 gagaaaattc aaatgactta tactttggaa tggctaaaga cttttgatgg agagattgat
     1081 attctcaata ttaagatgaa ttgcttggcc aatactattg agaaaaatgt ttctcagtac
     1141 aaatatattt atcagacaaa tatggagaac tgtcctgaaa ttattctatc agtcccaaac
     1201 tcctccattc ctcatctatt aggattatct agagaacatc atgttaattt accaactaat
     1261 aatgcaggga gtatttttga aggattaaaa gatgattgga cattggaaag cctgaataaa
     1321 gctgataatg gttggttcaa cgaaaataaa ttcaaaatag ttggaacctt gttgctttat
     1381 caaatgttac atgtaatgga gtgtaaattc tatacaactg atggcatttt gaatagaaga
     1441 gttggtagcc gatttagaag agataatatt tattttgtag tctttaaatt aagtaatggt
     1501 attagttata cagtagaact atcacgtgaa caaggtaatc aatactttcc aagaagcctt
     1561 aaaatcaatg atacctccgt tacagattgt agagaaatag atcttagact cattaataag
     1621 attagattta agccagttaa ggcaagaaag gtgaaatggc catcatgatt taaaaattga
     1681 aatcatgatt acatcactat tcttttctta acaaatgtga gtattgtcga agaatttctg
     1741 tatcgagaaa ttttatgaaa gttaatcaga aaattagata tcagagtttc tttgacaagc
     1801 attttatctt gctgtttgta tgtttttact agaaatgttt ctagggcttc atttggagtg
     1861 gaaactatta gtccatggct tacttcttct ttataatagg tggtctagct tacttataga
     1921 ttcagtttga aataaaaaac taaatgaatt gattttaaag aaataaaatg ctaacagata
     1981 tataagatgt tagcatttta tttctaagaa aggagaatga aatggttgat aaaagagaaa
     2041 aactgatgaa ctctttcaat cagtatggtt ttttaacttt taaacaagta atagatgaaa
     2101 atttacacta caaaacctta ttgaaaatgc ttgcagaagg aaaaatcgat gctgaagaaa
     2161 aagggttata tcgcttacct gatatttatt tagatgagtg gtttgtcctt cagtatcgat
     2221 ttccaaaggg aatcttttct ttggagacag cactttggtt acatggttta tctttgacta
     2281 tcccttttaa catgacgatg agttttcctt atggtacgaa taccaaaaac attaaggaag
     2341 cagatatatg tcctattatt ttacgctctc actatagtga aggaattatt gaaatagagc
     2401 gccttcctgg tcaatttatt aaagtttatg aagttgaacg agttttggtt gaatgtctat
     2461 gcccagctat ttaaagtaac tgataagtta caatcttata cggaggtgct atcttaatgt
     2521 tttttaatac aaaaacttta atagttttag aatttggttg atagcttatg aataaacagc
     2581 tatattgttt tgattattaa atattcaaaa atctattata taattagttg aaattatatg
     2641 ttgtaagtgt tataatgcag gcgaaaaggg ttgctctgga aaggagaaaa aacggaaact
     2701 atattttgag caattcataa ttttattgtt aaataaagct tttaattcta attatggaag
     2761 gtgaacagtc atgaaaacga gtaaaattat cctttctgtc ttaactgtaa ttattagttg
     2821 tagcttagcg tgtcctgtat ttgctgattg ggtatctggt ggtaactgga gttacggagg
     2881 ttatcataat ccaggcaatt ggggagcatt ctcaaattat ttccacgact atcgatggca
     2941 ttggtcaagt gtgactcgag caagtgacag caaagctaat gtaggttatg cttctgctca
     3001 ttacacatca agatcgttca taaatacaag ttttggtgaa actgcatact ttaattatgg
     3061 attttaattg ctaaagttta tcctagagag aagaaatctc tctagggtaa actagaaaga
     3121 gtagaattat gaaacgttta tttatacatt tctcgaacct ttttattcta atctttctgc
     3181 tttggattgc ctttatttca cctaatacgg tcatccatcg aagcctacct gtaataggga
     3241 ttcttcaaca agaaagggaa gttgtttatg aagagctttc atctagctta gatcagttag
     3301 caaaagaaaa caatagtttg attgctcgtc agattcaaaa aacggattct aaagggcaag
     3361 tcaagttttc gtatgatatc tacggagaag gagcacttcc taatggcatc aaaaaagaag
     3421 agaaagaatt cgttgcaaag gaaagtttgc ttaccaatta ctatatacta tctgggaatt
     3481 taacccttga aaaattagat caaaaactcc acgatcttgg tttttcaaaa agtttcatga
     3541 ataagcccaa tcccctgcaa aattttatgg tattttttag ttcgggttcc caatctctag
     3601 ccttggttat ttttatcatc agctttgctg cattgaccat tattcaaaaa acacttgaaa
     3661 tgagaagtgc agggattcgt tacatttctg gaataagacg ataccagctc tttggacatt
     3721 ctctcatgga agacggtaaa gaattgtttt tagggtgtat tggtggaagt gtcctaggag
     3781 ctattctgat ttattattta caattgactc cttttgccta ttctctcatc atttcagcta
     3841 gtattattta caatacactt ttatttattt tatctgcttt cctatccttt ttctttgcat
     3901 tcagtattca gacagtacac ttggttagcc ttttaaaggg gaaaattcca ttaaaaagag
     3961 tcttgttttt tctctttaca tgtcaatttc ttgcaatcac tgtcattggt ctctcaattc
     4021 atcgtgtcag catctatggc tctatctggc agacttatca agagggaagt ttggcttggt
     4081 ctaaagagac aaattggata caaattagtt tgaatcggga aaatgtttta caaacgacaa
     4141 acaaagaaat gcaaattgaa caaatagcta aatggtctaa actgatcgag tctggcattg
     4201 aaaaaggtgg acttttggtc catcatcagc ttgccgcatt taattcaaaa ggcttcatga
     4261 acgatcctag aacagggaga gagctttcga tcacagatta cgatcctctt gccaacaccc
     4321 tgtatgtaac accaaattac cttgatatcc aaaggatctt agtttcccct gaggaaaaag
     4381 agcgcttgaa tcacttgcaa gctggagaat ttggactctt gcttcctgaa aagttgaaag
     4441 ggcaagaaga ggagttgaaa aaacgctatg aagattatct gactcctagt gatgaacaag
     4501 gaaagagtca gttgcctatg aaagcacggg tgacctatct tcctaacaac caaaaacgat
     4561 ttatctataa taatacaccg atgatctatc agcaattctt gacagacccg attttggttg
     4621 ttgttctacc tagaagcttt ggtggctacg ataatcctta tttctctcat cttaattctt
     4681 atctttactt tgatggtctg gaaaaaagca agaaactagt agttgagaat gggcttgaaa
     4741 aaaatgttag tcaatatgac tatgcggcgt ctgtatacca gcagatgatc caatccattc
     4801 aattagagaa tctcattacc attgcaggag gaatctttgc aatagctact tccatactac
     4861 tctttaacac catgaatttc ctctattttg aagagtttag aagaccaatc ttcttgaaga
     4921 agattgcagg tctgggattt gtaaagattc accaaatgat tttgctctca gaaagtatcc
     4981 tcttactatt aggaagcttc ctgacattcc ttctcactca agaatggtgg attgctcttg
     5041 tcactctctt gctatttatt actaatgctt ggtttattct cctgtaccgg tctcataaag
     5101 aagaccactt gttagccact gtactgaaag gagcctaata tgattagcat agaacattta
     5161 accaaatcat ttggccaacg aacggtcttt caagatttga gcttgcaatt tacagaaggt
     5221 aaggtctatg ctctgatcgg aaatagcggg tgtggtaaaa caaccttgct taatatcttg
     5281 gcaaagttag agccttatga aaagggaagt atcagctatc aagggcaaga attgaaacaa
     5341 atcaaacagc atcacttctt taagcatgaa ttaggctatc tctttcaaaa ctttggccta
     5401 cttgaaaatg agactatcgc tacaaattta gatttgggat tgattgggca aaaattaacg
     5461 aaaaaagaga agaagcagca agaagaagaa gtgctcaaaa aagtaggatt ggcttacctt
     5521 gctctggatc aaaagatttt tgaattatct gggggagagg cgcaacgtgt cgcattagct
     5581 aaagttattt taaaagatcc acctttaatt ttggcagatg aactaactgc agcactggat
     5641 ccagaaacct cacaagaggt gatggacttg ctcttaatgt taaagaatca agagcgtata
     5701 atcattattg caacccataa tcccgatatt tggaatcaag cagatgaagt tataaattta
     5761 aatcaattat agttacagtc aatagatatc ttctatattt taaagttatt ttatctgaat
     5821 ccgtaaaagc agttcaattg aactgctttt ttcttctacg acttacactg tttggtttca
     5881 tgagcaagcc cctcaaagtg aattaataac aaatcattag aagtcatagt gatgaaattt
     5941 ctgtaacgga agtagagcga attgctgaac cattaaatga gtatctctcg aagtagaagc
     6001 gtctattttg acttttagtt tgatagaatg gtagtttgaa aatgtaaatg atagctactg
     6061 ttcataaaac atataaggta cgtacggtgt tgtgagagga gctagaaatt agcacttacc
     6121 ttattattcc aacaacccca aaaatgtgat aaaaatttca actactctta tctataataa
     6181 agctacctgt tctttgaaaa ttgaatccac tccgtcttga ttagcgtgcc tgtgtaagta
     6241 gggactgaga gtatttccct gtgaagggcg actggcacaa gacgtgtgtg agaattttct
     6301 aacagacacg gagtttatcg ttaccagact taaacgatgc gacaaactag ataaaggagt
     6361 taatcatgaa ggtagtaaac ttgtatgatt tgaaacaaat gggaaataaa ggtggttgta
     6421 ccatccaatt gattcatcac tttccttttg gtatgggctt aggacatctc aaaagagact
     6481 acattgaatt taaacgtgtt ggtatctttg atgggaaagc agtagaagtt actcttcgag
     6541 aaccttattc gagagatcta ctgcaggttg tcaagtcgat taagcaacgt cagaaattga
     6601 tagcttatcg ttataaagaa ggaaagctgc tatttgttaa gaaggaggca tcagatgtcc
     6661 tctgaacaac aggaacgaat ggcagttcaa tatgctgagc gtagtctttt atttactgta
     6721 aaaagtcttt taaagattct agaatggtct agacgtcagg ctttagcaca agattccgcc
     6781 tataagatag gggtgcagaa attagaagaa ttgctacaat ctccctattc gattgatacg
     6841 attaatctga aaaaagattt tttagacaaa ccaattgata tagagaaatt taaagctttt
     6901 ttagaaaaag aagagattcc tttagccatc gcttggcaag gggattctct gcatttctac
     6961 acgaaagacc gttcgattct agacaatcat ttagaccatc tgttagaaaa aatggttaat
     7021 gatccggaga aattagctga ttttatcatg gataagtcat tagacgatgc aattgatgag
     7081 gctaaatccc aaattacctt tagacaagaa ggtgccgtca aacagaaaga gatggtgaga
     7141 tgatgtacag tggaaagaaa ttcatactat tctcactgtt aggtatctta ctaggctatc
     7201 tttttcatcg tttgacgctt ttgtatgatt cctatactgg aaatacatta gataaatgga
     7261 ttcatcttct gatggaaggt caagatgaag ttcttcagtc gccatggaat gtttccttta
     7321 ctggaaaatc aagtgctttt tttctactag gctttgtgat gatgttgctg gtttatctct
     7381 atctagagac tggtaaaaaa caataccgag aaggggtaga atacgggagc gcccgttttg
     7441 gaactctaaa agaaaagaag ctcttttacg gtaaggaatt tttacatgat acgatcttag
     7501 cacaagatgt tcgtttgaca ttattagata aaaaaccacc ccaatatgat agaaataaga
     7561 atattgcagt gatcggaggt tcaggaagtg ggaagacatt tcgctttgtg aaacccaatc
     7621 taattcagat gaatagttct aatattgtag tggatcctaa agatcacttg gccgagaaaa
     7681 caggaaaact ctttttagaa catggctacc aagtaaaggt gttagattta gtcaatatga
     7741 agaactcaga tggcttcaat ccttttcgct atatagagac agaaaatgat ttgaatcgca
     7801 tgctgacggt ttatttcaat aacaccaaag gctctggctc tcgtagtgat ccattttggg
     7861 atgaagcttc tatgactttg gtccgagctt tagcctccta cttggtcgat ttctataatc
     7921 cacccaaaac aagagaacag ctcatagaag aaagtcgttt aagtcaaaaa gaatacaaaa
     7981 acttgttgaa acgtcaaaaa aaagaagtgg aggagcgaaa aaaacgaggg cgttatccaa
     8041 gttttgctga aatctcaaaa ctcattaaac acttatccaa gggtgaaaac caagaaaaaa
     8101 gtgtcttaga aattctattt gaaaattatg ctaaaaagta tgggactgaa aattttacca
     8161 tgcgaaattg ggcagatttt caaaattata aggataagac tctggattct gttatagctg
     8221 taaccactgc taaatttgcc ctcttcaata ttcagagtgt catggatttg accaaaagag
     8281 atactcttga tatgaagaca tggggcaagg aaaaatcaat ggtttactta gttatcccag
     8341 ataacgatag tacctttcgc tttctttcag ccctcttttt ttcaacagta tttcaaactc
     8401 taacaagaca agcagatatt gattttaagg ggcaattacc tcttcatgtg agagtctact
     8461 tagatgaatt cgcaaatatc ggagaaatcc cagattttgc tgaacaaacc tcaacagtcc
     8521 gttctcgaaa tatgagtctc gttcctattc tacaaaatat tgcccaactt caagggctct
     8581 ataaagaaaa agaagcttgg aaaaccattc ttgggaactg tgatagctta gtatacttag
     8641 gtggtaatga tgaagatacc tttaaattta tgagtggttt actcggtaaa caaaccattg
     8701 atgttcgaaa tactagtcgt tcctttggcc agacaggttc aggatccctt tctcatcaaa
     8761 agattgctcg tgatctaatg acacccgatg aggtcggaaa tatgaaacgg catgaatgct
     8821 tggttcgaat tgccaatatg cctgtcttta aaagcaaaaa atacaattca accaagcatc
     8881 caaactggag gtacctagcc aatcaagaaa gcgatgaacg gtggtggaac tatcaaatca
     8941 atcctttgaa tcaaaatcaa gaaaatcatc ttgaaggcct tagaattcgt gatttaactt
     9001 ttgaatctag tttaaaataa aaatagaaaa gaggaaatac atgtttacgc attttaaagg
     9061 ttttgtttat ggagtagacg caagtgctat gtttgcacaa gctatgtctt tgttacagaa
     9121 gggattgatt gccgttggtg cctttctcgt tgttgtgggg attgtcaatc ttgcaaccaa
     9181 cattaaagat ggaggaccag gtgttcggaa tgccattctt gaaattgtcg gtggagttat
     9241 ggtcggggct gctggagcct ttgtaaccca gatttcaatt taggaggata aacaatgaca
     9301 tgaatcttag tttagtctca ccctttgttt accttgcatc tgaaaaaata tcagctgaaa
     9361 atttatttga aggatttaat gtagatttac aatctacggt agatctgatt aaatcactat
     9421 ctaactacaa tccaaccgtt tggacttata tgtctagtat tactaaaagt gtcatgcagc
     9481 cccttggagt tgcgatttta tcggttgttc tcatcctaga attttcgaag atggctaaga
     9541 aaattgctaa ctctggtgga gcgatgacct ttgaagcctt agcgccaatg ctgattagtt
     9601 atattatggt cgcagttgta attaccaaca ctaccgtcat tgtagaagcc atcatcggga
     9661 ttgcgagtca tgccattgaa caagtggcct cgattgtggc tcacggtggg gcaaagtatg
     9721 atacactctc tggattaaaa gggtcaggat ttattggccg gatgattgtg ggctttttcg
     9781 ccctcctcat ttggcttgtt cggatagtaa gtgcagccat ggttaatctt ttggtatcta
     9841 ttcgatttat tcaactctac cttatgatcc catttgcccc tcttacgatt ccaacatttt
     9901 taagtgatga atggaagtct attggtttag gctatttaaa aaatattatg gtctatgcgg
     9961 tacaaggggt tcttattttt ctgattgttt ctcttgttcc tttgtttgaa tctgctggta
    10021 aaatagctgt ttcaaatggt gcaggagtcc tgcaatcact tgcgattatg tttggtagtt
    10081 tggtacaagc tatcttactg attattgccc tcgttggttc tcaacgtacg gctcgctcaa
    10141 tcttaggtat gtaattagat aaaggctagg aagtggttgc ttcttagcct ttttagaaag
    10201 gaaagtcatg aatacacgtg tctttaaaga catctcaaaa taccaacaca gggcttggtt
    10261 aggtttcacc acaagacaaa tcatctttgt tttaccagcc tttattgtca caattattgt
    10321 tttgggcttg aatctctttt tctggcaatt tggagattgg tttgtttacg gttttgtgtt
    10381 tgcttttacc atccccctct tgctttttgg agtctataaa cccaatgatt tatattttga
    10441 acattatttg aaataccgtc ttcattttga actaacgata cccctacgca caatttcagg
    10501 aaagaaagga cttgaacatg aaaagaaaat caaatacatt aaagaaacaa aagacttcaa
    10561 cgactaataa aaaggaagaa gttaaagata aaaaagagga agtgttacca tcaacggcta
    10621 atactctttc ctatcaagcc ttgtatcaaa atggtctgat gcaggtaaaa gaagattatt
    10681 tttcacaaag ctatttactt ggtgatgtca attaccagac cgttggttta gaagataagg
    10741 gagcaatcat tgagaagtat tctgatttga ttaactcttt agatgaccaa accaacttcc
    10801 aattgaccat ttttaataaa agattgaatt tagaaaaatt cagacacagt gttttgtatg
    10861 aggaaaaaga agatgggtac gatagctatc gtaaagaatt gaatcggatg atgaatcaaa
    10921 atttagatag tggtgaaaat aacttttcgg ctgtgaaact gattagtttt ggtagaaagg
    10981 attctaatcc caaacaagct tatcgttcct tgtctcaaat aggcgaatat ttcaagagtg
    11041 gtttctcaga aattgatgct cgatttggat ccttgactgg agaagaacgg gtgaacttgt
    11101 tggcagatat gcttagagga gaacaccatc ttcctttttc ttatcgtgat ttaacgagat
    11161 ctggccagac aactcgtcac ttcatagcac ctaatctctt ggattttaaa aacaagaatt
    11221 acctacaaat caatgaccgc ttattacaga ttgtctatgt gagagactac ggtatggaat
    11281 taggggatca gtttatccga gacctcatgc aaggagatct ggaattgatt gtaagccttc
    11341 atgctcaaag ttcgaccaag gcagatgcca tgaagaaact acgaacaaag aaaaccttaa
    11401 tggaatccca aaagattggg gaacaacaaa aactagctcg tacaggtatc tatttggaaa
    11461 aagtaggtca tgtattagaa agcaatatcg atgaagctga ggaactctta aaaaccatga
    11521 ccgagacagg agataaacta tttcaaacgg tcttcttgat tggggtcttt ggtcaggatg
    11581 aagaagaact caaacaagcc ctagacacta tccaacaagt ggccggctca aatgacctaa
    11641 tgattgataa acttccatat atgcaagaag cagcctttaa tagtttgctg ccatttggtt
    11701 gtgatttttt agagggagta tcacggagtt tattaacgtc caatatagca gtgaactcac
    11761 cttggacttc agtagactta caagaccgta gtgggaaata ttatggtatc aatcaaatct
    11821 caagcaatat tattaccatt gatcgcagcc tattaaatac accgtctggt ctgattttag
    11881 gaacatctgg agctgggaaa gggatggcaa ctaagcatga aattatcacg accaaaatca
    11941 aggaatctgg tgaaaatact gaaattatca tcgtggatcc agaagcagaa tacagtgtca
    12001 ttggacgagc ttttggggga gaaatgattg atattgcgcc cgattcccaa acttatctca
    12061 atgtccttga cttgtctgag gaaaatatgg atgaggatcc tgtaaaggta aaatcagaat
    12121 ttcttttatc ttttattggc aagttattgg atagaaaaat ggatgggaga gaaaaatcga
    12181 ttatagaccg agtcaccaga ctcacctatc agtcatttaa agagccttct ttggaagaat
    12241 gggtctttgt cttgagccaa caaccagaag aagaagcgca gaatttggca cttgatatgg
    12301 aactgtatgt tgaaggttct cttgatattt tttctcataa gaccaatatt cagacaggat
    12361 ctaacttctt aatctataac gttaaaaagt taggagatga gctgaaacaa atcgctctta
    12421 tggttgtttt tgatcagata tggaatcgtg tcgttcggaa ccaaaaatta gggaagaaga
    12481 cttggattta ttttgatgaa atgcagcttc ttttattaga taaatatgcc agtgatttct
    12541 tctttaaatt gtggagtcgt gtcagaaaat atggagccag tccgactggg ataacccaaa
    12601 atgtcgaaac cttattgtta gatccaaatg gtagacggat tattgccaat agtgaattta
    12661 tgattctcct caagcaagca aaaaatgacc gagaagaact agttcaactc ttaggcttgt
    12721 caaaagaact cgaaaaatac ctagtcaatc cagaaaaagg ggcaggacta ataaaagctg
    12781 gttcagttgt cgttcccttt aaaaataaga ttccccaagg tacacaattg tttgatatca
    12841 tgagtacaga tcctgataaa atggcttcta attaagggga aggtaaatga aggataagag
    12901 agaaatcata cgtgcccgaa aggcatttag aagaagtcta aaagatgaga agaaattctt
    12961 aaaacaagga aagaaggagg tgagaaaaca gaaaaaagat tccgctgtac tggatgaaaa
    13021 agcatggaaa aatgagataa agcaaaagct ggagaatatg agagaagctt caaaggctag
    13081 agtaaaacaa gcaaatgaag actacaatca tattcttcaa aatagtcctc catcactttt
    13141 gaatcggaaa gaattaagag atagacgatt gcctcatgct aggaaacgat tgaaaatagc
    13201 caagaaacaa tttaaggaag ctaaggttga agcaaaagaa gaaagaaaag agagtcgtaa
    13261 agaaagaaaa accaatcaaa aatttttcta cggtcaggaa acgaaagtaa aatccaattt
    13321 tttccttcaa gggaagaatc tagaagaatt aaaagctaag aaagaagtca aagccgcaaa
    13381 agagaatcta aaatctacta agcaagccta taagttcaaa aaaatcagta ggaaagccaa
    13441 aacctttctt tatgtccttg gacgtgaagg tggagagtta gcttcagaaa atgaagattt
    13501 agaaagttat cgcacacttc atgagaccat tagaaaaggg aaacgctaca gtcggctttc
    13561 ttataatctt ggaaaagcta gtgtcaaaac aggacaagca acaggtcgtt ttaccaagaa
    13621 aagactgacc aacacaaaag agcgatacca tcattttaag gatggaaaag gatggaaact
    13681 aactaaagat aatccaagtt cctttaaaaa tcggtatcga aaattaaaga aacaaggtct
    13741 tttaagtgtc cgaaatatct atcaaaaatt aaaaggagcc ttttccttct ttacatttgt
    13801 ggctggaaat cctgtaatct ggatagttgg aggaatagtc tttcttcttt tacttatgat
    13861 gagcttcttt ttaggatttt catctgctag tttgattcaa caagatgaat ttgaattaac
    13921 aaaagcttat acccacctaa cttgggaaga tgcagaacat actcgtacaa atgacaaagg
    13981 aattacctat tacacaaaag ttgatgatgt gatgggctat atgaacttta aattccatga
    14041 ctatgagtta cagaaaccag ttcatttgtt tagttcagaa acttacaagg attatctatc
    14101 tgctttgtgg catgatttaa acgatgggga agatttgaaa tccatgcaag acctttatga
    14161 aactcctaag tataaactct cgaaagacga tcaagaggaa ataaaggaac taaaagaaga
    14221 aggtgtgtat gcttccatgc aggaattgga caatccattt gaggggaaaa gtaacgaaga
    14281 tagtttgacc atgacttatc gttatggata ctatgattta gacggaaaac ctactcttca
    14341 ggagtacatt ctattagaag cgaaggctca ccaaacgatt gtcgcaccaa tggatggagt
    14401 tgtatctcta gatggagatg atgttattct cactaacgga aaaggtgaga atgagagtcg
    14461 tttaacctta tattccattc ataatggccg tgcgattgag gggacaaggg tcttaacggg
    14521 tgatgttatt ggtgaaacac cagatgatac aggtttgaaa gtttcctatc aaaagtataa
    14581 gaacaagaaa gaaaaattgg tatatgtcaa tccgcaattt tattttccaa aagtcattca
    14641 acttcagaca actatcttac ctgccattgg tcagtttggt ggagatgagt ttgaacgagc
    14701 aaaacatatt tatgattttt tgaaatctca aggggcaagt ccccaagcca ttgcggctat
    14761 tttaggaaat tggtcggtag agtcttctat caatcctaaa cgagctgaag gggattattt
    14821 atctcctcca gttggcgcta ccgattcctc atgggatgat gaaacctggt tagcgatagg
    14881 agggccagcc atttatagtg gtgcttatcc taatatcctt catagaggtt tggggttagg
    14941 tcaatggacg gataccgcag atggttcaac acgtcataca gctttgttaa attatgcacg
    15001 cacccaaaat aagaaatggt atgatttaga cctacaactt gattttatgc ttcatgggga
    15061 tagtccttac tatcaaagtt ggttaaagga tttctttaaa aatacgggca gtgcagccaa
    15121 tctcgcccaa ctcttcctca cctattggga gggaaattct ggtgacaaac tactggaaag
    15181 acaaaccaga gcaacggaat ggtattacca aattgaaaaa ggcttcagcc aaacaaatgg
    15241 aggacaggca aaaagtgacc cgcaatccct tgaaggtgtt cgtggagact tgtatgaaca
    15301 ttctgttcct ggtggtggag atggtatggc ctatgcctat ggacaatgta catggggtgt
    15361 tgcggctcgt atgaatcaat taggcttaaa attaaaagga agcaatggag agaagatttc
    15421 aatcattaat accatgggaa atggtcagga ctgggttgcg acagcttcaa gtcttggtgg
    15481 agaaacgggt tccacaccaa gagcaggtgc tattgtttct tttgtaggag gtacacatgg
    15541 tacaccagct atctacggtc atgtggcttt tgtagagaag gtctatgatg atggttcttt
    15601 ccttgtgtct gaaactaact atggtggcaa ccctaactat acctttagaa aaatctctca
    15661 tgcagatagt gccattagtt ttgcctatac tacgaaataa agaagtttac acttgcaatt
    15721 ttagctattt tcaggtaaaa taaatagtgt agatgagtgg tcggctcatg gtcaatctga
    15781 tagtaatctt ggacgtaagg gccaagcggt ggcggacacc agaacgaaat ccgatagcaa
    15841 tcttggacgt aagggccaag cggtggcaga caccagaata aaccgactga ctaggtggct
    15901 tacagactct gtaaaccacc tttttttgtg aggaaaatat ggcaaattct agagattatc
    15961 gtaatccaaa ttacaccgaa acaataaaac ttcagcgttt ttttacacag ttacaaattg
    16021 cggcttcttt ttttaaagaa cactttgttg gcaaaattat gtattatgaa acggaaattg
    16081 aaagtgttga acttcatttt tcacctacta atttcatgca cctatgtggt gttgattacc
    16141 gaaaaggtgc aggcagtttc tttgacgatt gtttaaatag acatgtcata attgatgagt
    16201 tgaaaataaa aaaagatgga accacgatgc aaaagttaca agttttagga tccattgggg
    16261 agttattggg aaagcatgtt catctaactg gttcaggacg ttatttgtat ttggagtttg
    16321 attatgctct acgtacaaga aaacagataa tagcattaac attgaaagag acctctagga
    16381 aaattgttcc tcaatcttta ttagatttga agagaaagac agtatttcca aaaggtcaaa
    16441 aagtaatttc aatttactca aaacatttac aaacatcgga acttttttat tatttaaaag
    16501 attagtttac atatcttttg tggtataaaa tatattttta tcattttcag gagaacgcag
    16561 ttttggctcg ttctcttttt ttgttgtgat acttctttca aggaatattt ggtaggattg
    16621 gagtgaaaaa aaattaacta ggaaagaagg aagtatatgg aagccattta tcaacgtgat
    16681 tcggatcaag atggattaac tgatgctcaa gaattggccc taggaaccaa tcctcttagc
    16741 tcagattctg atggtgatgg acgttcagat ttagtggaaa tagaagaagg aaccaatccc
    16801 ttagaaaagg atttacaaga catagaccaa acaagtatca ctgaatcgtc atcagtattt
    16861 atggaaatga aacaaaagat ttcagatatg atggagagtc actacaagga atttatactg
    16921 gctctgatta gtattgaaac agggattgaa aaccaacaag acctagaaga cttatatact
    16981 tactacatga gaatggatgc cgtttctctt ttatctagtg atttagaaac cagtcctcaa
    17041 gaggttgaaa tggagataga gttgtagggg aatcatgtga ttctcctatt ttcgtataga
    17101 tgaaaggagc gagtatggaa gtaatacaat tattggctat gtttcgtgga acaattccaa
    17161 aagataggga taaaatggac ctatttcttc gctatcaggc gcaacatttt gatgagaaat
    17221 ggcaggactt ggtagagagt tttttgactg aagaggagaa gatagaagag atacctcatg
    17281 tctattcgtt tcatcaagac attgtttctt tcctagaggc cagttctgaa aataatgacc
    17341 aagatctaga aagttacaca agaaattttg gacaagcagg actagataaa ttatctcaat
    17401 taagtaattt tgagaaaaat ttggtgctaa aagtcgcaag ctataacctt tccactcgat
    17461 tttacatcca atctgaaaaa gagaaactaa caccattaag tgagcttgta tttcatcaga
    17521 atcaggatgt taatttagtc aatgtctatc gggttgcgaa taatctatct gaccgtatta
    17581 gtagagatat agaggaattt cttctaatgg ttgactcaaa agaggttaaa aaagaagttc
    17641 ctgagattca ttttgaagaa aaagagggag atgttctagc ctatttgggt tcagaattga
    17701 tggctacttt agatatcgtt acggatcttg tccatcatga agaaaactac atacaactcc
    17761 cactgacaca aaagctgaag attattactc attttgatga agtaaaagct aaaagcgaaa
    17821 agtctaatca agtagagaaa attttatctc cttcaagtga tattgaacag gaaacggaag
    17881 aaactaactc cttttctaat gtcgataaaa ttgtagaaga agctttgagg gaatatccaa
    17941 tcggttcaca agtaagttat aaaggacaag tatttcagtt ggtttcgatt gaaaatgcgc
    18001 agttaaatga cttagttcgc ctagagctat tcaatgattc caaccagtta tttgaagaga
    18061 atcctatctt atacttgaac agtttggaag agattgaaca agtattgtct catttagaac
    18121 ttgaaaaaga agattcagag attgagattg attcatcaag tgaaagtcag gaaatagatt
    18181 tgttttcata cctggaagaa gaaaatgtaa atgaaaagga taaggataag gaaacaaaat
    18241 ctttaatttc aggtatagaa gagacggatg tccctgttct agattttgtt tttccagatg
    18301 atttagagga cttttatcct aagacaaatc gagaaaagat tgaaacgaat atcgccgcaa
    18361 ttgaacttgt taaaagatta gaaaaagaga gacgacaagc gaatccagaa gaacaagagc
    18421 tactcgccaa gtatgtcggc tggggcggtc ttgccaatga atttttcgat gaactcaatc
    18481 caaagtatga aacagaacgt ttaactctta agagcttagt aagtaaatca gaatactcga
    18541 ccataaaaca aagttctctc acagcctatt atacagaccc aatgattatt cgccagattt
    18601 ggcaaaaatt actggatgat ggttttgagg gaggaaggat attagatcct tctatgggga
    18661 ctgggaactt ctttgcggcg atgcctagaa gtatacgaga gaaatcagaa ctctatgggg
    18721 ttgaattaga cagtgtgact ggtgcaatcg caaaacaact ccaccccaat acccatattg
    18781 aagtgcgagg atttgaagaa gttccctatc aaaataatag ttttgattta gtcttaacga
    18841 atgttccttt tggaaatttt cgcattgccg ataaaaacta tgataaacct tatatgattc
    18901 atgattactt tgtcaaacac tcacttgatt tagtaagaga cggaggacaa gtgtcgatta
    18961 tctcatctat tgggacaatg gataagcgga cagataatgt cttacaagag attaaatcca
    19021 atactcattt tttaggggga gttcggttgc cggatacggc ttttaaaaag attgcaggta
    19081 cccgagtgac cacagatctc ctattctttc aaaaggatca agcaaagaat cttaatgagg
    19141 aggaacttgt ctttagtggc tctgttccct ttgaggagga taagcgtgtc tggatcaatc
    19201 cttattttga tgggaaatac aatacacaag ttttgggtga atatgaggta cgtaatttta
    19261 atggaggaac cctcaatgtt aagggggaat cagaaacatt agctactgac ataatgaaag
    19321 cattagagaa tgtagaagca cctaaacaaa ttgacaattc tttgaaagca cctgttttta
    19381 tccaagaaga agtggataat tctatcccaa gtcatatacg tgagaactta gcgctctatt
    19441 cttttggata tgagggaaat caaatttatt atcgagatac gcatggcatt cggagaagtt
    19501 caaaagtaga cgaaattagt tattatgtag atgagaaggg agattttaaa gcttgggaca
    19561 gttccttgtc tgaacataaa atagatcgat tcgtgcaact tcatttgaca gatgaggaag
    19621 cactagatgt atacaagtca gaagaagcga gtaaaagagg gaaatataag ggcttgttca
    19681 aaaaaacggt cttttatgaa agccccttat cggataagga tattagtcgc attaagggca
    19741 tggttgattt gagagagacc tatcaagcct taattgaaat tcaacgccat ccagattata
    19801 gtcggacaga ttttcaggta ttacttagta aactcaatcg tgactatgat cggtttgtaa
    19861 gccaatttgg atacttgaat gtctcagtca atcgaaactt atttgatagt gacgataagt
    19921 attctttact agcaagttta gaagatgaat acattgattc taaagatcag aaagtaaaat
    19981 ataaaaaatc tttagccttt gagaaagcat tggttaggcc ggagagagtg attacaagag
    20041 tttcaacggc tttagatgcc ttaaactcca gtttatcaga tggtagaggg gttgatatag
    20101 actttatggt atcaatttac cctgaacata gccaagcagc tattttagat gagttgggtg
    20161 accagatctt aatggatcca gaaagctatt taagagggga aagaaattat ctttctaaga
    20221 accagttttt gtcaggagat attctcaaca agatagaagt agttcaacta ttagtagagg
    20281 aaaacaacca agaatgtgat tggactcatg cgttagattt gttagaatct gttcgccctc
    20341 caaggattca tctggcagat attgagttta aaatagggtc acgttggatt cctcaatccg
    20401 tttatggtaa atttgccttt gaatgtttta ccaaccgtga atttgaattg tcttcgcctg
    20461 atgttgaaca agtcattgaa gtgaatcctg tcgatgggca ggttcattta aggacaccat
    20521 ttgcttatcg ctatccaagt gccaaagata gtagtcttgg agtcagtggc tcacgttatg
    20581 atacaggaag aaagattttt gagaatttac ttaattcgaa ccaaccgact attactatga
    20641 ctgttacgga aggggaaaag aaaaagacca tcacagattt ggaaaaaacc tctgttctaa
    20701 gagcaaaaga gcagcattta caagaactct ttcaagactt tgtctcacgg tatccagaag
    20761 ttcaacaagt cattgaagaa agttataatc gtctttataa tcgaacggtt agtcgagagt
    20821 atgacggtag ccatttagtc attgatggct tggcacaaaa catcagtctt cgtcctcatc
    20881 aagagaatgc cattcaaaga attgtagaag aaaaaagagc cttgttagct catgaggtag
    20941 gttcaggaaa gaccttgacc atgcttggtg ctggctttaa attaaaggag ttggggatgg
    21001 ttcataagcc cttgtatgtg gtgccctcta gtttgtctgc tcagtttggc caagaaatca
    21061 tgaaattttt ccctactaaa aaagtctttg tgaccactaa gaaagatttt gtgaaggcaa
    21121 gaagaaaaca gtttgtgtca cgtattatta caggagatta cgatgccatt gtcattgggg
    21181 attctcaatt tgaaaaaatc cctgtcagta aggaaagaca gatgaattat atcgaggata
    21241 aactcaatga actacgagag attaaaacac attctgaaaa taagtacacc gttaaagaag
    21301 cagagcaatc aataagtggt cttgagaaac aattggaaga actccaacgc tttaatcgtg
    21361 atagttttat tgattttgag aacttaggaa ttgattttct ctttgtggat gaagcacatc
    21421 actttaaaaa tatacgtcca attactggac ttggaaatgt agcagggatt accaatacaa
    21481 cgtctaagaa gaatgtggat atggaaatga aggttcgaca gattcaggaa gaacatgatt
    21541 ttaaaaatat tgtctttgcg acaggaacac ctgtttcaaa ttcaattagt gagctgtata
    21601 ctatgatgaa ctacattcaa ccggatatct taaaacgcta tcaagttgat tattttgact
    21661 cttgggtagg tgcttttgga gaaattcaaa actctatgga attagctcct acaggggata
    21721 agtaccagcc taagaaacga tttaaaaagt ttgtcaatct acctgagttg atgaaaatct
    21781 ataaagaaac agccgacatt caaacacaag atatgttgga tttacctgta ccagaagccc
    21841 atattatccc tattgagagt gagttaactg aaaaccagaa actctatcta gaagaattgg
    21901 ttatgagatc agatgcggtc aaatgtggaa cagttgatcc aagtcaggat aacatgttaa
    21961 aaattacggg tgaggcacga aaattagcta ttgatatgcg tttattggac tctagttata
    22021 gtctagcaga caatcataaa ctgcttcagg tagtggataa tgttgaaaga atttatcgtg
    22081 agggaatgga aaataaggct actcagatga ttttttcaga tattggcaca cctaagaaaa
    22141 aagataatgg ctttgatgtt tattctgaga ttaaggcttt attagttgat agaggaatcc
    22201 ctagtatgga aattgccttt gtacatgatg ccaatagtga tgaaaagaag aatagcttgt
    22261 ctcgaaaggt taatgcagga gaggttcggg ttcttcttgc ctcaactgaa aaaggaggaa
    22321 caggtttaaa tgttcagagc aagatgaaag cagttcacca tctggatgta ccgtggagac
    22381 caagtgacat tcagcaacgt aatggacgta ttatccgaca gggaaatgaa aacaaggaag
    22441 tggatattta ccactatatt accaaaggtt cgtttgataa ttatctatgg gcaactcagg
    22501 agaacaaact ccgttatatt aagcagatta tgacttctaa ggagccgatt cgtgctgcgg
    22561 aagatattga tgaacagact atgacagctt ctgattttaa ggcactagca acaggtaatc
    22621 cttatctcaa atataagatg gaactagaga atgatctaac tctattagaa aatcaaagac
    22681 gcgcctttca acgcagcaag gatcactatc gtcatacaat ctcttactgt gaagaaaata
    22741 tgcccattct tgagaaacga ttaagcaagt atgaaggcga cattcaacag tctgaaatgt
    22801 cgaaagacca atcattttct atgacgatag gtaaacaagt ttttgagcaa cgagctgaag
    22861 caggtgaatc cctacaccgt cttatccgtc ataatcaatc tgacagcaaa gaatttcgaa
    22921 ccctagcaag ttatcgagga tttgacatta aaatgcttag tcttgcaaca aatcaacctc
    22981 ttcctgaaac cttctctgtt aagattgtag gagaaaacca atattctgtc agtttagatt
    23041 tgtattctcc tttggggaca attcaaaggc ttcagcatac gatagaccac attaaagatg
    23101 accaagtgaa aactcagaac ttattggatg aattaaagga taaatggact actgctaagg
    23161 tagaaattga gaaaaatttt ccaaaggaag aggattatca aactaaaaag gccgaatacg
    23221 atgtactcgc gccattgatt gaaacagaaa cggatttaga tattattgat caggccttac
    23281 gacaattcca cgaaaaagga aaagaaaagc aagaacaact ttcttttgaa ttagattaaa
    23341 aaatagatat aaatagcgga caagaaaaga aaagcgcggt agaataaaga tagaaagaaa
    23401 cgaggtaacg attatgatgg aagataccta ttatcaatta gaagaggctt tggtacaggg
    23461 atttcaaaca cctgaagaat accaagccta caaggagtta aaggaacatt atgaggaagt
    23521 gacaggggat tacagttttt ctaaacgaga gctcactagt caattggaaa tcgctcttca
    23581 gaatcatcaa ggtgtggact ttgaagaaca tgaaaaagaa gagtatttgg acttagttca
    23641 aaaattagaa gagtttgatt cctctcttgc cacccattat cgtcagttga ttgattagaa
    23701 aggagaaagt catgaatgat ttactcctta tcccagtaat ttttttagca gtaggaggaa
    23761 ttatcattct tttatggaga ctctttctta ttgccagtgg acttttcctt attggttttg
    23821 tcagttttct tattttcgta gaggtctatg gaatttatct gttctttact gaacctagtt
    23881 tatattttga tgatatcaga caatatggtt taactagttt tacggctgtg taccttttca
    23941 tcaatctgat gttggttcta ggatttagtt ggcgcttcat taactccata aataagcata
    24001 aaatgtgaac tttttagata gttaaaagac tttattcaaa ggtaagtttg aataaagtct
    24061 ttttgttgat gtgcttataa tcccgtctta gtacttagtg tgagaaacaa aaagagatga
    24121 attaaaatta aagtgtacag aatgcttaag agtttctatt tttcttataa tatatagtaa
    24181 tttcggtaca aattaacttg tatatttt
//
LOCUS       DAVHSH010000023        24041 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000023 DAVHSH010000000
VERSION     DAVHSH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.023"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            468..1589
                     /gene="mnmA"
                     /locus_tag="VVR08_001128"
     CDS             468..1589
                     /gene="mnmA"
                     /locus_tag="VVR08_001128"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU6075053.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFALECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1730..2185
                     /locus_tag="VVR08_001129"
     CDS             1730..2185
                     /locus_tag="VVR08_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6075054.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPGWEGQLRHIHLEE"
     gene            2195..4108
                     /gene="mnmG"
                     /locus_tag="VVR08_001130"
     CDS             2195..4108
                     /gene="mnmG"
                     /locus_tag="VVR08_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU6075055.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDAVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKDRHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4303..5982)
                     /locus_tag="VVR08_001131"
     CDS             complement(4303..5982)
                     /locus_tag="VVR08_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6075056.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(5984..6217)
                     /locus_tag="VVR08_001132"
     CDS             complement(5984..6217)
                     /locus_tag="VVR08_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU6075057.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6866..7129
                     /locus_tag="VVR08_001133"
     CDS             6866..7129
                     /locus_tag="VVR08_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075058.1"
                     /translation="MDRSLFPIGSYGNYCGYGNNGYSIPAIDDLDMACFYHDKCFKGF
                     LADNRSCNIAFLARLSPIVANNAWNTTKGAYARAAVVLFSRFV"
     gene            7362..7577
                     /locus_tag="VVR08_001134"
     CDS             7362..7577
                     /locus_tag="VVR08_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075059.1"
                     /translation="MYNLFAFAIGVRVVAFIVFIACVYGGNLLFAKLERRQTKFLWKI
                     TFVTLYSLFLLLVTYVVWFVFYFGLNA"
     gene            complement(7880..8032)
                     /gene="cibB"
                     /locus_tag="VVR08_001135"
     CDS             complement(7880..8032)
                     /gene="cibB"
                     /locus_tag="VVR08_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU6075060.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(8034..8219)
                     /gene="cibA"
                     /locus_tag="VVR08_001136"
     CDS             complement(8034..8219)
                     /gene="cibA"
                     /locus_tag="VVR08_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU6075061.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8397..9080
                     /gene="tsaB"
                     /locus_tag="VVR08_001137"
     CDS             8397..9080
                     /gene="tsaB"
                     /locus_tag="VVR08_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU6075062.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKDASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            9077..9514
                     /gene="rimI"
                     /locus_tag="VVR08_001138"
     CDS             9077..9514
                     /gene="rimI"
                     /locus_tag="VVR08_001138"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU6075063.1"
                     /translation="MIEIKRIQQQPDLAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9504..10514
                     /gene="tsaD"
                     /locus_tag="VVR08_001139"
     CDS             9504..10514
                     /gene="tsaD"
                     /locus_tag="VVR08_001139"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU6075064.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWNLNAKPSLAFDT
                     ME"
     gene            complement(10554..11860)
                     /locus_tag="VVR08_001140"
                     /pseudo
     CDS             complement(10554..11860)
                     /locus_tag="VVR08_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12136..12487)
                     /locus_tag="VVR08_001141"
                     /pseudo
     CDS             complement(12136..12487)
                     /locus_tag="VVR08_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12594..12887)
                     /locus_tag="VVR08_001142"
                     /pseudo
     CDS             complement(12594..12887)
                     /locus_tag="VVR08_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13130..14335
                     /locus_tag="VVR08_001143"
     CDS             13130..14335
                     /locus_tag="VVR08_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6075065.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPYDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            14328..15281
                     /locus_tag="VVR08_001144"
     CDS             14328..15281
                     /locus_tag="VVR08_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6075066.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            15291..16907
                     /locus_tag="VVR08_001145"
     CDS             15291..16907
                     /locus_tag="VVR08_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075067.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            17166..17594
                     /locus_tag="VVR08_001146"
     CDS             17166..17594
                     /locus_tag="VVR08_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075068.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQILVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17606..18354
                     /locus_tag="VVR08_001147"
                     /pseudo
     CDS             17606..18354
                     /locus_tag="VVR08_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
     gene            18367..19545
                     /locus_tag="VVR08_001148"
     CDS             18367..19545
                     /locus_tag="VVR08_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU6075069.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTGTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNE
                     LDSFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAP
                     VIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVG
                     IKILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD
                     "
     gene            19941..20804
                     /locus_tag="VVR08_001149"
     CDS             19941..20804
                     /locus_tag="VVR08_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6075070.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYVPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLIALFE
                     LRFQQYKELID"
     gene            21090..21323
                     /locus_tag="VVR08_001150"
     CDS             21090..21323
                     /locus_tag="VVR08_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075071.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            21345..22022
                     /locus_tag="VVR08_001151"
     CDS             21345..22022
                     /locus_tag="VVR08_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075072.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22034..22699
                     /locus_tag="VVR08_001152"
     CDS             22034..22699
                     /locus_tag="VVR08_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075073.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            22771..23997
                     /locus_tag="VVR08_001153"
     CDS             22771..23997
                     /locus_tag="VVR08_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6075074.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7329 a         4022 c         5095 g         7595 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga tggctataaa gtcaatgcca atggtgaatg
       61 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
      121 agataaggtt cgattgaata gatttatgtt cgtattcttt aggtacctat cttatgattt
      181 caggaaatgt cattaaaaaa acgactcctt ttctctaact tgaaaaatag attagagaaa
      241 atgggttgtt ttatttatta tagttacttg aatgaagata agaagaaggt atactcacgt
      301 cattcacata atctgtatgt tgactataag ttttaaaaaa caatttttaa gctcttcctt
      361 gtcttctcta accaagcgtg ttataatgaa tactgctcaa gcgaccttca atcgtgaagc
      421 acacacgacc ttcaatcgtg aataaacgaa tagatgggag acttaccatg agtgataact
      481 ctaaaacacg tgttgttgtg gggatgagtg gtggtgttga ttcgtcggtg acggctcttt
      541 tgctcaagga gcagggctac gatgtgatcg gtatcttcat gaagaactgg gatgacacag
      601 atgaaaacgg cgtctgtacg gcgaccgaag attacaagga tgtggttgcg gtggcagacc
      661 agattggcat tccctactac tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg
      721 agtatttcct agcggaatac cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca
      781 aggaaatcaa gttcaaggcc tttttggact atgctatgac cttgggggca gactatgtag
      841 cgactgggca ttatgctcga gtggtgcgtg atgaggatgg taccgttcac atgcttcgtg
      901 gcgtggacaa tggcaaggat cagacctatt tcctcagcca actttcgcaa gaacaacttc
      961 aaaaaaccat gttcccacta ggacatttgg aaaagcctga agttcgaaaa ctagcagaag
     1021 aagcaggtct ttcgactgct aagaagaaag actcgacagg gatttgcttt atcggagaaa
     1081 agaactttaa aaactttctc agcaactacc tgccagctca gcctggccgt atgatgactg
     1141 tggatggtcg cgatatgggc gagcatgcag gtcttatgta ctatacaatc ggtcagcgtg
     1201 gcggactcgg tatcggtggg caacacggtg gtgacaatgc cccttggttc gttgtcggaa
     1261 aagatctaag caagaatatt ctctatgtag gacaaggatt ctaccatgac tcgctcatgt
     1321 caactagcct agaagccagt caagtccact ttactcgtga aatgccagaa gagtttgcgc
     1381 tagaatgtac ggctaaattc cgttaccgtc agcctgactc taaggtgacc gtccatgtca
     1441 aaggagacaa ggcagaagtt atctttgcag aaccacaacg cgcgattaca ccaggacagg
     1501 cagttgtctt ttacgatggc gaagagtgtc taggtggcgg tttgattgac aatgcttacc
     1561 gcgatggaca agtttgtcag tacatttaga ttgacaaatt ttctcaattt gctacaataa
     1621 taacagcaat agaaatgatg gtcaaagctc atggatgttg caggcttttt tgtcctgcac
     1681 ttctttgtag ttttgactgt ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca
     1741 agactttcgg acaaaagtag acaatacggt ttttggtgtt cgggctacag ccttgattgt
     1801 ccaaaatcac aagcttctag ttaccaaaga caagggcaag tattacacta ttggaggtgc
     1861 gattcaagtc aatgaaagca cggaagacgc ggtagtccgt gaagtgaagg aagaactggg
     1921 tgtcaaagct caagctgggc agctagcttt tgtggttgaa aatcgttttg aacaagacgg
     1981 cgtttcctat cacaatatcg aatttcatta tctggtggat ttgcttgaag atgccccgtt
     2041 gaccatgcag gaagatgaga aaaggcagcc ctgtgagtgg attgacttgg ataagcttga
     2101 ggatatccag ctagttccag cctttttaaa aacggcccta ccaggttggg aaggccaact
     2161 aagacacatt catcttgaag aataggagag aaacatgact tatcatttta ctgaagaata
     2221 cgatattatt gtaattggtg cgggacacgc tggggttgag gcttccttgg ccgctagccg
     2281 tatgggctgt aaggtcctgc ttgcgactat taacattgaa atgctggctt tcatgccttg
     2341 taatccctct atcggtggtt ctgctaaggg gattgtcgta cgtgaagtcg atgccctcgg
     2401 tggcgagatg gccaagacta ttgacaagac ttacatccag atgaagatgc tcaacacagg
     2461 aaagggtcct gccgttcgtg cccttcgtgc gcaggctgat aaggaacttt actctaagga
     2521 aatgcgcaag acagttgaaa atcaagaaaa tctgaccctt cgtcaaacca tgattgatga
     2581 gattttggtg gaagatggca aagttgtcgg tgttcgtaca gcgactcatc aagagtatgc
     2641 tgctaaggct gttattgtga cgacagggac tgctctccgt ggggaaatta tcatcggaga
     2701 cctcaagtac tcatcaggtc ctaaccacag cttggcttct attaacctag ctgacaatct
     2761 caaggaactg ggtctcgaaa tcggtcgttt caagacagga acccctccac gtgtcaaggc
     2821 ctcttctatc aactacgacg tgacagaaat ccaaccagga gacgcagtac ctaatcattt
     2881 ctcatacact tcacgtgatg aggattatgt caaagatcaa gtgccatgct ggttgaccta
     2941 taccaatggt accagtcatg agattattca aaacaacctc caccgtgcgc ctatgtttac
     3001 aggtgtggtc aagggagtgg ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg
     3061 ctttgcggac aaggaccgtc accaactctt ccttgagcca gaagggcgca atactgagga
     3121 agtctatgtt caaggacttt caaccagtct gcctgaggat gtccagcgtg acttggttca
     3181 ttccatcaaa ggtttggaaa atgcagagat gatgcggaca ggttatgcta ttgagtatga
     3241 tatggtcttg cctcatcagt tgcgtgcgac tttggaaacc aagaaaatct caggtctctt
     3301 cactgctggt cagacaaatg gaacgtcagg ttacgaagag gcagcaggcc aagggattat
     3361 cgcaggtatc aatgcggctc taaaaatcca aggcaagcct gagttgattt tgaagcgcag
     3421 tgacggctat atcggggtca tgatcgacga cttggtgacc aagggaacca ttgaacctta
     3481 ccgtctcttg accagtcgtg ctgaataccg tctcattctt cgccatgaca atgccgatat
     3541 gcgtttgaca gagatgggcc gtgagattgg ccttgtggat gatgaacgct gggctcgttt
     3601 tgaaatcaag aaaaatcaat ttgataatga gatgaaacgc ctagacagta tcaaactcaa
     3661 gccagtcaag gaaaccaatg ctaaggttga ggaaatgggc ttcaagccgt tgacagatgc
     3721 ggtgacagcc aaggaattcc ttcgccgtcc agaagtttct taccaagatg tggtggcctt
     3781 catcggacca gctgcagaag acttggatga caagattatc gaattgattg aaacagaaat
     3841 caagtacgaa ggctatattt ccaaagccat ggatcaggtt gccaagatga aacgtatgga
     3901 agaaaaacgc attccagcca atatcgactg ggatgacatc gattctattg cgacggaagc
     3961 tcgtcagaag ttcaaactca tcaatccaga aaccatcggc caagccagcc gtatttcggg
     4021 agtaaaccca gcagatattt ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat
     4081 ttctaaaact cttcaaaaat caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa
     4141 gcttggcttt gattcatctc caacctccca tagttccccg aactatggga gctaactcaa
     4201 gttatgcatt ttcctagcct tctggtctga ttttcattga gttttaatct caaaagaaag
     4261 catagagaaa aacagctccg aagacggggc tgttttcttg ctttattctt catctggtgt
     4321 gaggatcatc gggatgatga tcggttcacg ttcggtattt tcatagagga aggggcgaat
     4381 agcgttgaca atggcaccat tgacagattg cacgctagca tccttatttt tcagtgcgat
     4441 acgaatggca ttgaagagga tacgctggct ttggcgaatc aagtcgccag actctctcat
     4501 gtagacaaag cctcggctga ggatgtctgg accagataga atcatctgcg atttgaagtc
     4561 aacagttgcg actgccagaa cgacaccgtc ttcagataga tcgcgacgat ctttgaggac
     4621 agctgcgcca atttcaccga tacgatttcc atcgacatag atatcttggg cgttgaaatg
     4681 acctgcgata cgagctgagt cagcagtaag ggcaagcaca tcgccattgc tcatgataaa
     4741 gatattgtct ttctcaacac cagtatccac tgctagtcca gcgtggactt tttgcatgcg
     4801 gtattcaccg tggacaggca tgaagtattt tggcttaatc aagcggagca tgagtttttg
     4861 ctcttgctga ccaccgtgtc cagatgtatg gatattgttc actttaccgt ggataacttc
     4921 gacaccagct tcagaaatga tgttaatcag cttgttgacg ctagtagtgt ttccagggat
     4981 gggactagaa gagaagataa cggtatcacc tggttgtaat tgtacttgac ggtgggttcc
     5041 gttggcgata cgagagaggg ctgccatagg ctccccctga ctacctgtac agaggataag
     5101 aacttctcct gcaggataat ctttgatttc atttggctcg ataaaggttc ccttaggagc
     5161 tttgatgtag ccaagatcga ttccgttgac aatggccttt tccatagaac gaccaaagac
     5221 cgcaatcttg cgtccagtct taacagcagc ttctgttgcc tgctggagac ggaagatatt
     5281 tgaggcaaag gatgcaaaga tgatacgtcc ttcaatacct tggataatct tcataatgga
     5341 ctgaccaacg actttttcag agttggtaaa ggttggtact tccgcatttg tcgagtcaga
     5401 caggagacag agtacgcctt cttcaccaag ggcagccata cgatgcaagt ccgcaggttc
     5461 tccaactgga gtaaagtcga acttaaagtc acccgtacag acgattttcc cttgaggagt
     5521 atgaatgaca atccccaaag gctctggaat agagtgagtc gttctaaaga aagttgcctt
     5581 gagattttta aaggtcaact cggtgttgtg gttgatttcg taaagtttgg cgttgcgcaa
     5641 gaggccgtgt tcttcgagtt tcccacggat caaagccaag gcaagcggtc cagcataaat
     5701 agggacattt gcttgcttga gtaggaacgg aatcccacca atgtggtcct cgtgtccgtg
     5761 tgtgattaaa acagccttga cgcggtcgat attgtctacg atgtaagagt agtcaggaat
     5821 gacatagtcg ataccaagca agtcatcttc tgggaattta atcccagcat cgacgatgat
     5881 aatctcgtct tggtattcaa ttccgtaagt gtttttcccg atttctccta gaccaccgat
     5941 ggcaaaaacg ccgacttctt caggtttaag agtgtaggcc atattagaac tccgtaattt
     6001 cgaaggcgcc agtttctttt tcgtaatcga gcaatttgtc agacaagagt tcgatatatt
     6061 cgatattgta ctctgggcga ttttcttcga caagttggcg agcagtgata cggccctcaa
     6121 gttctgagct ggcatcgatg tctaggtaaa gtgcgcgtgt agtttcacga cgtgggctac
     6181 gttcttttgt ttcttgataa aaaactttgt aaatcatata gttcctttct atttacaggt
     6241 cagcttattc caaactttta gcatagattt gcttgatttc attccatttt gtgtctagat
     6301 tgaccttgat tcgttacaat tatttcaatt ataccacaaa atgaaaaatt agtaaaagac
     6361 gggaacgaga aagtcagggg acgatttctt tagtaagcgc ttgcaatttc aaaaagtatg
     6421 tgctaagtat gtgctataat aatagaaaga aatagtctaa gctggaaagg aaataattcg
     6481 gaaactatat tgtttagtgc tattgctatt atgtttaact ttatagatac tattgatgta
     6541 tttgatagta tgagctcaat agagaaagga ttctgcgatg aaacataagt ttagttttat
     6601 tttgatcgtt ttggcttttt tcaccacaac tttatttgct atttatagtt ctgcttcagc
     6661 actagagtct aatcacagag tagaatattc ttggttatct gaattggata aagttaccga
     6721 attgaatgaa catggtttcc ctgtagttag attagataaa gcagaggagc ttggtttaga
     6781 taatgaagct ttggaggtag ggcgtgtttt aaacgaaatc gtaacggata tagagactaa
     6841 cggagagtca actgctttgg ctagaatgga tcgctctctt tttcctatag gctcttatgg
     6901 taattattgt ggttatggaa ataatggata ttctattcca gctattgatg atttagatat
     6961 ggcttgtttc tatcatgata agtgttttaa gggattttta gcagataata gaagttgcaa
     7021 tatcgcattc ctagcaagat tatctcctat tgtagcaaat aatgcttgga atacaactaa
     7081 aggagcatat gcaagagcag ctgtggttct attttctaga ttcgtataag accaagtttt
     7141 tgtaaaatat gagttgttac gtaaaagtgt tgatatgagt attggtgtct atgaacagaa
     7201 tcttatctta taagttttaa cttatctttt aaggtttctg tttataggcg cttgtagatg
     7261 tgtttatgtc tttaaaaaat atatttgcga tattaaaaat ggatacttat gcaatatttc
     7321 actttactta ttaagataat tttaaactaa ggaggttccc tatgtataac ttatttgctt
     7381 ttgctatcgg agttcgcgtg gtagctttta tcgtttttat tgcttgtgtt tatggaggga
     7441 atcttctatt tgccaaactg gaacgacgac aaaccaagtt cttgtggaag attacctttg
     7501 tgactctcta ttcgcttttt ctcctccttg taacctatgt cgtttggttt gtattttact
     7561 ttggattaaa tgcttagatg ccctgcctat gttggggcat ttttgtttgg gggcaaagaa
     7621 aattccaccc catctatcaa gatgaggtgg tctttgcatt tttctaacat gacatgacaa
     7681 tggaattttc aaagcttatt atttttatgg gagtcattgt tctactcaaa aatagagttg
     7741 aagcataaaa ataaaacaat acaaacagat aaatcgaatg gtaaagggat agtagtaatg
     7801 cttaaatcat tgagaatgct gagcaaactg taagagatga agacaataaa atttatcctt
     7861 ctaaaaatgt gtttcttatc tagcatgact taccaaactt tttacgaagg tcttttccaa
     7921 tggtataacc tgccataaat aaagcgatac caacaccgac accaaagcca cccttgattt
     7981 cttgcaattc cttattagaa atttcacgat aattgttcaa atctttcatc atattaatct
     8041 cctcctaaaa aataaccagc tgccaaacca gaacctataa gtgctgttcc acctgcaata
     8101 gccttccaag atactgctac tccaaagata accaagggag cgagaccgcc atcaatatct
     8161 gataattcat tttcagataa ggataaaaat tgattgtcaa gaatgtcaaa atttgtcatt
     8221 gaactttcct ccttttttct tgttcacttt tatattcgga aaagaaaagg aaaagtgagc
     8281 atttttttaa attattttta gttaagtgag ggcactcttg tctgggggca aagaaaattc
     8341 ccatgtgcca gcttttgtag tataatagta agcagacaaa aagataggaa tgtgttatga
     8401 aagtattagc ttttgatacg tccagcaagg ctctttctct ggctatttta gaggacaagc
     8461 aggttcttgc tgagacgacg attaatatca agaaaaatca cagtattacc ctcatgccag
     8521 ccattgattt tttgatggag agtttggact ggacgcccaa ggatttggac cgaatcgtgg
     8581 tggcggaagg gccaggtagc tacacaggct tgcgaatcgc ggtagccact gccaagacct
     8641 tgactcatac tctgaacatt gagttagttg gtatgtctag cctcttggct ctggtgccat
     8701 atcaacaaga aggcttgttc gttcctttga tggatgcgcg tcgcaacaat gtttatgcag
     8761 gattttatga aaatgccaaa cctgtcatgg cagaagcaca tctgcctttt gagcgagtca
     8821 ttgagctaat caaggacgct agtcaggtaa cctttgtcgg agaagttggc ccctttgttg
     8881 agcagattca aaaacacttg ccaaggactg attacaaaga aacattgccc aatgcagcta
     8941 atctagctct tttggcctgg gacaaggaag cagactcctt gcatgatttt gtgccaaatt
     9001 acctcaaacg tgttgaggca gaggaaaact ggctcaagaa ccataccgag tctggtgaat
     9061 cctacattaa acgcctatga tagaaatcaa acgaatccaa cagcaacctg acttggctca
     9121 agatatctac gctgtcatgg cagctgttta cccagtcagt ccttggacac tagaacaaat
     9181 ccaagcagat ctgtcccaag accagacttg gtatgctctg gcctatgatg gggcagaagt
     9241 gattggcttt ctaactgttc aggagactct ctttgaagca gaagtcctgc aaatcgctgt
     9301 caaaggagct tatcagggtc agggaattgc gtcagccttg tttgctcaat tgccgacaga
     9361 caaggaaatt ttcctcgaag tcagacagtc aaatcaacga gcgcaagcat tttacaagaa
     9421 agaaaagatg gcagttatcg ctgagcgaaa ggcctactac catgacccag tcgaggacgc
     9481 cattatcatg aagagagaaa tagatgaagg atagatatat tttagcattt gagacatcct
     9541 gtgatgagac cagtgtcgcc gtcttgaaaa acgacgatga gctcttgtcc aatgtcattg
     9601 ctagtcaaat tgagagtcac aaacgttttg gtggcgtagt gcccgaagta gccagtcgtc
     9661 accatgtcga ggtcattaca gcctgtatcg aggaggcatt ggcagaagca gggattaccg
     9721 aagaggacgt gacagctgtt gcggttacct acggaccagg cttggtcgga gccttgctag
     9781 ttggtttgtc agctgccaag gcctttgctt gggctcacgg acttccactg attcctgtta
     9841 atcacatggc tgggcacctc atggcagctc agagtgtgga gcctttggag tttcccttgc
     9901 tagctctttt agtcagtggt gggcacacag agttggtcta tgtttctgag gctggcgatt
     9961 acaagattgt tggggagaca cgagacgatg cagttgggga ggcttatgac aaggtcggtc
    10021 gtgttatggg cttgacctat cctgcaggtc gtgagattga cgagctggct catcaggggc
    10081 aggatattta tgatttcccc cgtgccatga ttaaggaaga taatctggag ttctccttct
    10141 caggtttgaa atctgccttt atcaatcttc atcacaatgc cgagcaaaag ggagaaagcc
    10201 tgtctacaga agatttgtgt gcttccttcc aagcagcagt tatggacatt ctcatggcaa
    10261 aaaccaagaa ggctttggag aaatatcctg ttaaaaccct agttgtggca ggtggtgtgg
    10321 cagccaataa aggtctcaga gaacgcctag cagccgaaat cacagatgtc aaggttatca
    10381 tcccccctct gcgactctgc ggagacaatg caggtatgat tgcctatgcc agcgtcagcg
    10441 agtggaacaa agaaaacttc gcaggctgga acctcaatgc caaaccaagt cttgcctttg
    10501 ataccatgga ataaagagtg gctctttgtc aagtgtagtg ggtaggcgaa aagctacaat
    10561 ctggagagta cgaaattcgt actctctttt ttgatgttca aagtcatcaa aatccgtttt
    10621 ttaaaattgt taaagttccg gaaaccaaag gctttgcgct tgataacctt aatcaaatta
    10681 ttggtcgctt caagtttagc gttggaataa ggcagcttaa gtgcgttgat aatcttatct
    10741 ctatccctta aaaaagtcca aaagaccgtt tgaaaaagcg gatgaaccgt tggcagttct
    10801 tgctcaatca atccaaagaa atggtcggca ttcttctctt gaaaatgaaa gagcaggagt
    10861 tgatagagtt cgtagtgaac ctgtaatccc tcagagtaag aaagcagctt atctcgtact
    10921 tcccgatggg ttaagtgcat tcgaaacgtg ggctgataga atcgtttctg acagagcttg
    10981 aagctatact ggtgtagtaa atcagtccag tggactgatt tagcccgagc ctagaaacga
    11041 aaaagcgagg gttccaaaag cgcttgagcg cccgatactc caaggatttt cggtcaaatt
    11101 ggttcatgat ttggattcgt actcggttca tagctcggct cagatgttgg acaatgtgga
    11161 agcggtcaag aacaatcttc gcctttggaa agagttgctt agcgagccga taataagggc
    11221 tgtacatgtt catggtgatg acctcgacca gctcccgaac ctctctctga tagcgttgga
    11281 aatggtttcg aatcaccgca tgagttcgcc cgtctaaaat tgcgaggatg gatttggact
    11341 caaaatcttg ggcaatgaag ctcattttgc tctttttgaa gctatactca tcccaactca
    11401 taacttttag caacttggtc caatcggttt caaacttaaa ttccctcagt tttcggatga
    11461 cggtggaagt tgagaccgcc aatctgtggg caatctcagt catagactgc ttttcaagga
    11521 ggagctgagc gattttttgt ctcaccatgt tggaaatctg gcaatttttc ttgacaatgg
    11581 atgtttgaga aacgaccacc ttaaggcaat tcttgcactg aaagcggcgc tttttgagat
    11641 gcagtaccgt gggtaaaccc tgacagtcga gaagcggaat tttagaggct ttctggaagt
    11701 cgtatttgat catcttccct tgacaatgag gacaaggagg agcgggggaa tccaactttg
    11761 cctgaacgac tagatgggtt tggtatttca gaacagacaa gattttgata tttttgtctt
    11821 ccaatccgag caaatctgtg gtattcttaa gttgttccat atgaaccctt tctaatgagt
    11881 tggttagacg cttttcatta taggtcatat ggggcttttt ttctacaaga aacgacccta
    11941 taattcctgg ggtgggatta cccactacag aaattataga gccaaagcat tccaaagtct
    12001 tgtctgactc tggaatgttt tctgttcaca gttgttttgt aactgcctaa taagtaaccg
    12061 cgctataacg aggtatctac cgagattgtc aattctccag tatactgtta taaaaaacaa
    12121 aactggagga tttttttatg tccccccatc gtcccatcga ctgttccgta gctgcccaat
    12181 aacggagtat agtcggctga aacaagaata ggacaaaagt gcctcaagaa aagcatcgta
    12241 atttgacaat attattctga gatgtttttg atgtaagccc atattttctc aatgggatta
    12301 tactcgggtg aataggtagg aagtggtaac agtctatgcc ctgctcctta cacatgttca
    12361 ttctgtgaaa ccttgcatgg tccataatga taagggatgg tgtatctaaa gtaggtagta
    12421 agaatttttg gaagcaagct tcgaaaaagt cactcgtcat cgtatcttta taggtcatcg
    12481 gagccatagt atattgaaac aaaaaagggc attagtactt ctataacagt atcgcaatct
    12541 ctggtgtgcg ttgtctcgat cttaattcaa ataattatat cttcttccag agagactaac
    12601 tgcctgctca aggctcgatc atattcgaga taaaaatagg tctcaacccc tgtctcataa
    12661 atataaatag gagtcaggta gcttaagtga ttcaattctt taaggaaccg atttactttt
    12721 tctgggtctt gttcgcagta ggtacggctc ttttttagac tatatcccat agcctttaga
    12781 gcgtaatgaa tagttgttgg aggacagttg aattcagcag ctatttcagt caaataagca
    12841 tcgggatgag tttcaatata gatctttaat ttatctctat caactttttc aattaatagt
    12901 ggaagttttc ttgaagttag tgtattgaaa cgtttttata cagtgctaaa atttgaagtg
    12961 tagtgcagat gtatttgtaa tagtattata gcaattcttt ggagaaggtc gagacaagat
    13021 aaaataggta tctttgagat ataagcatga tttactataa aattattgag ttattcataa
    13081 aaatttctct atcaaatatc ataatgcgtc gtttaaggag atggttacaa tgcaatatag
    13141 ttgtggaaaa ataaatatta atatccctga tggatatgga gacattaagg atatagtgtt
    13201 ttcggctcat attatagtta ggtataataa tggacattgt ggaggtatag atccgcatat
    13261 aattggactt tgtaaaaagc agatcagaag gatgtctcta tatcctattt tgataatcgt
    13321 atctagagat tcaaaggtta ttgatgatta taaaaattta gatattgcct atgttgattg
    13381 tactcaatgt tcaaataatt ttgaaactgc cttacacgtt aaaaatattt taaaattatt
    13441 aaaaatccaa cttatacact gtcatggcta ctcaactaat tattttttat atatgttaaa
    13501 aaaacttgac aagaatggat ttggaaaggt taagacagtg ataacatgcc atggatgggt
    13561 tgaatataac ttaaaaaaga aattcttgac ttattttgat ttttggacat attctatggg
    13621 agatgctttt atttgtgtat ctgaaactat gaaaaaaaga ttggagagta taataaaaaa
    13681 taagaagata gttgcaataa ataacggaat taatgtatca aatagcgatt tagatgtagt
    13741 aggtgttcaa gactttaaaa aagaattttg tattccaaat aacaaaaaaa tcatttgtta
    13801 tgttggaagg ttggatccag aaaaaaggcc ggatagattc cttgaatttg cagaaaaatt
    13861 atttttagtc agagaagatg tgatttttat tatggctgga aatggtagta tgtgggctgc
    13921 tttgaaagaa aaaatttgcc atttgaaatg tagagataat ttcaggttac ttggtgaaat
    13981 ctatccagct actatagttt accaaatatc ggatttattg tatattcctt atgatacaga
    14041 aggaatacct atgtgtgttt tagagtcaat gtcacaagga actccggttt tagctagtaa
    14101 tgttggcggg ttaagtgaaa ttattgaaca tagggttgat ggatttttat ttgagaagga
    14161 agatgttgag ggagtgtgtg cttgtgctaa ttttttactc aatgattctg agtatttgaa
    14221 atatataggt gagaatagta aatcaaaaat aagaaaacat ttttctgtgc aaaaaatgtt
    14281 tgtagaaacc atgagagtat atgatgaatt attagagaag agtagtcatg gataggaata
    14341 tagatcaaga attagtaagt attataatac caacacataa taggtatgaa tctctgatta
    14401 gagctgtgaa aagttgttta catcaaagtt ataaaaatat cgaagttata attattgatg
    14461 ataattatag taatgtaaat ttaagaaata aaattatcca tcaatttggc tataccaatc
    14521 atagaattaa gttaatttta agtaatgaag atttaggtgc aactaatgcc agaaacatag
    14581 gtataaaaaa ttctagaggt aagtatatat catttttaga cgatgatgat gaatatatgc
    14641 cagatcgaat tttaaagttg atggcttgtt ttaaaaagag tagaatgaag aatttagctt
    14701 tagtttatag ttatggaata ataatttatc caaatggtac acgagaagag gagaagaccg
    14761 attttgttgg aaatcccttg tttgttcaaa tggttcacaa tatagcaggt acgtcatttt
    14821 ggttgtgtaa aaaagaggtg ctagaattaa ttaatggttt tgagaaaata gattcacatc
    14881 aggacggtgt tgttttatta aaactacttg ctcaaggata ccaaattgat atagtgcgag
    14941 aattcttggt gaattactac gctcacagta aagaaaacgg tatcactgga gtgacacaaa
    15001 aaacaattaa tgcagatgaa gaatattata attactgtag gaaatatttt aatttattga
    15061 gtttcaacga gagaatattg gttacaaaga aatattattc tttaaacata aagcggttac
    15121 tattaatagg agacaaatgc aaggctttaa aagtaatcaa gaaggcaaga gaagaaaaaa
    15181 tttttaacga atttcttttt ttgaaataca tgttattata ttattttggt tttttctatt
    15241 gtatatatga caactatgtt caattaaaat ttagaaagtg agaaactatt gtgtatacta
    15301 ttataaaatc aaatataaaa aaatttagtt tattaacgat atttattgtt gctggtcaat
    15361 tattgctaat ttatgcagca actattaatg ctctggtgtt gaatgaatta attgcgatga
    15421 atttagagcg gtttttgaaa ttgtcaatct accaaatgat tgtctggtgt gggataatat
    15481 tccttgactg ggtagtgaaa aattatcagg ttgaagtgat ccaagagttt aatctagaga
    15541 ttcgaaatag agttgccaca gacatctcta actctaccta tcaagaattt catagtaaat
    15601 catcaggaac atatctttcg tggctaaata atgatgttca gactttaaat gatcaggctt
    15661 ttaaacaact ttttttagta ataaaaggaa tttctggtac tatatttgca gttgtgactc
    15721 ttaatcacta tcattggtca ttgactgtag ccaccttgtt ttcattaatg attatgctac
    15781 ttgtaccaaa aatctttgca tcgaaaatgc gagaagttag tctaaattta actagccaaa
    15841 atgaagcttt tttaaaatct agtgagacta tattgaatgg atttgatgtg ttagcgtcct
    15901 tgaatctttt atatgtattg cctaagaaaa ttaaagaagc aggaatttta ttaaagatgg
    15961 ttatacaaag aaagacaact gtagaaacgt tagcaggcgc tattagcttc tttctcaata
    16021 ttttttttca gatatctctc gtttttttaa caggctatct tgcaataaaa ggaatagtga
    16081 aaattggtac tattgaagca ataggagcac taacaggtgt tatttttaca gcgctaggtg
    16141 aattaggagg tcaattatcc tctattattg gtacgaagcc tattttttta aaattgtatt
    16201 caattaatcc aattgagtca aataaaatga atgatatcga accaaatgag gtgaatagag
    16261 attttccgtt atatgaagca aaaaatattt gctataagta tggagataaa gaaatattaa
    16321 aaaacttaaa tttttgtttt caacgtaatg aaaagtattt aattttaggt gaaagtggaa
    16381 gcgggaaatc tacattatta aaattattga atggcttttt gagagattat agtggagaat
    16441 tgcgattctg cggggatgat ataaaaaaaa cctcctattt aaatatggtt tcgaatgttc
    16501 tatatgtaga tcaaaaagct tatttgtttg aaggtacgat tagagataat attttattgg
    16561 aagaaaatta tactgatgaa gaaatactac agtctttaga acaagttggt ttgagtgtaa
    16621 aagattttcc taataacatt ttagattatt atgttggtga tgatgggaga ttactgtcag
    16681 gagggcagaa acaaaaaatt actttagcta gaggcctaat tagaaataag aaaatagtat
    16741 taattgacga gggaacttct gctatcgata ggagaacttc gttagcgatt gaacgtaaga
    16801 tattagatag agaggatttg actgtcatta ttgttaccca tgctccgcat ccggaactta
    16861 aacaatattt tactaagata tatcaatttc caaaggattt tatttaagaa tataggggag
    16921 ggaaacatga gattctattg tgaagcttat gaggtaatta ctgaagagaa aaaagtatca
    16981 tttttttatg tagatgaaaa acccttaagg tatctgttat ttgactatat atttctacta
    17041 gttctagcta aaaaaatatc ccaatcttat gaactgcacc ccaaaagtta gatttattct
    17101 gtctaacttt tggggtgcag ttcattttgc atagttttgg cattcatcct agatatccat
    17161 ataaaatgtc tgagattgtt gaaatgtcta aaaaaatatc agatctaaac gataaaaaag
    17221 aatttcacaa aaagaactgt gagttgaggt ttcaagatag tgttcttgat aacataaata
    17281 gtgtcccggg tacaactcat ttatttagtt gtttaaatat tcaaatatta gtaaaaatta
    17341 ttttatatat ttttcgatac aacagttgta tgaaaatatt taattttaga gataaagagc
    17401 ttatcttttt taataagatt gtaaatgggc tgatacaaaa tattgaggag aatttagagg
    17461 atgatattga aaggatattg aaatatttat atatatgttt atttaacgaa atattcatta
    17521 ttaagaataa ggtgaatttt tttgatgatg tggaatttaa tcagacactt agtgagtttt
    17581 tagataaatt gtagagggaa tggttatgag taacaatact aagtatatct ttttatctcc
    17641 acatttagat gacgcaattt tttcctgtgg tgattatatt tcaaaattaa cttcagaagg
    17701 agaaattgta cttgttatta ctatattttc tggttaccct ttgagccaac agctacagtc
    17761 ctctgctaag caatttcata agttgtgtaa ccttgggaaa tatccgattg aagaaaggaa
    17821 gaaagaagac aggttagctt gtgaacgtct acaatgtgat tttagacact tatcgtacta
    17881 tgaatgtctc tataggaaag atagaaatgg caattttcta taccgtcata tctatagtga
    17941 attaaaaaat gaggacacat taaagaatga tatcataaaa gagctgttaa tgcatttaga
    18001 cgacaaatgt gtcgtatatt gtccgctttc acttggtgac catgttgatc atgtttttgt
    18061 gaatagtatt ggaagggcgc ttgaatttat gcgttataaa gtaatatatt atgaggattt
    18121 cccatatgta agtgatagta gtatggttag ttatatggga aaaactaaag aattaaaaat
    18181 gtatcaagag gaacttgatg aaaaaattat attgatagaa tatcatcaat attgtgctat
    18241 aaatctcaga ttttgataat ctggaaatca gttgaaaaac ttttaaacaa tattaaagag
    18301 ttgtatttaa ggaatggggc agcttattct attagatttt ggattaagaa ataaggaagt
    18361 agttttatga atatagcagt aattggtttg gggcatgttg ggctggccta cgcgttacta
    18421 tttgcatcta aatataaagt tgttgcatat gatatagatt ctgtaaaaat aaataattta
    18481 aaaaagggca ttcttccatc taaaaatgaa gagcttatga agtttttttg cgagaataac
    18541 ttaaatatta ctttttttga tacattttct gaaattaaaa ataatattga ttattatatt
    18601 attgcgcttc cgacagatta tgatgagaaa attggtagtt ttaatacata tgaaatcgaa
    18661 caaacggtat cgaagattct gagggtaaaa cctaatggaa agattatttt aaagtcaaca
    18721 gttccgatcg gcttttcaaa caaattaaaa aggctgtttg atacaaaaaa tatcattttt
    18781 gtccctgaat ttttgagaga aggttgttct atatatgata atttatatcc aagtcgcata
    18841 gttgttggag atgagacagt tgaaggaaga aaaattgcag agttgttcct ttcgattagt
    18901 actcatagta ctggtactgc caatattaaa aatgttatgt tagtttctcc tactgaagca
    18961 gaagcaatta agcttttttc taacacattc ttagctctcc gtgttgcttt ttttaatgaa
    19021 ctagattctt ttgctgagag gagaagttta aatgctgaag ttgtaataaa aggtgtttgt
    19081 ttagatccaa gaattggaaa tttttataat aatccttctt ttggatttgg aggatattgt
    19141 cttcccaaag atactaaaca attaaaaaaa gaatttatag aaataaatgc cccagtgata
    19201 gaagcgattg atatttcaaa cacaaataga aaacagttca tagttaaaca aatattggaa
    19261 cgaaagccaa agatagtagg aatatataaa ttggggatga aatataattc agataattac
    19321 aaagagtcag ctattttaag tataattaat gaactattga ttgtcggtat aaaaatttta
    19381 gtatatgaac caaatttaaa cgttagtata gataacgtaa tttttgaaaa gaattttgaa
    19441 ctatttacaa aacaaagtga tctaattgtt gcaaatagat gggatagggg ccttgaagct
    19501 tataaagata aagtttacac aagggggatc tggataagag attaactatt gatattaaaa
    19561 aggcaataat ttataaaatt tgtacaaaaa aatgttaaat tttcacattt tcatagtata
    19621 ctgtttaata gaaagtaggt tctttgtaac cgctccatta taaaatcctt tcactcttcc
    19681 ggtatactat taggaaaaac ataactggag gatattttga gctcacacct catcgttcca
    19741 gtggctgttc cccaagctcg tgtactgccc aaaaaagtta gacattctat ttagaacgag
    19801 gattgagttc tgtattgtac aaggctcggt ccttttagag tcagcttaag gctggctttt
    19861 ttattttttc taactatcag aatattttga caaatgaaca caaataatga tataatatgc
    19921 aaaagctagg aggtggtagg atgattgaaa aaatggaatt gggggaattt tacaaggaat
    19981 tacgtttggc gagaaagctc aagcagtcag atgtggcttg tgacgggcta acagcttctc
    20041 agttgtccaa gtttgagcta gggcagtcca tgttgtctgc tgataagctc atattagcca
    20101 tccaagggat caatgtgacc tttgatgagt ttgggcacaa gctcaacaac tatcaagaat
    20161 ctccacatat gcagattggt agaaaggttg tggatcgctt tgctcatcaa gatatagctg
    20221 gcttagagca actgttggag gaagtcgagc aagaacagat ggcagagact tatcgtcgtt
    20281 tgaatgctat tgtaatcaaa gatgccatcc actcactaga taaaagctac ccactagcag
    20341 aggaggatag cgagtttttg accacctatc tctatgctat cgagtcttgg acctggtttg
    20401 aactctatct cttttgcaat accatgccct tcttgagcaa tcaagatctg atttttttat
    20461 caacctcctt actcgaaaaa tccaaagaat ttaaagagtt agtacacaat cgattgtata
    20521 tgaagcaagg actcttaaat atcttatcag aactcatgga gcgaaaactt ttctcctacg
    20581 tcccaatctt cgaagccgag ttggagagga tgttacgacc gtatgatgtt tttgaaaaag
    20641 tatcgtggca atttttaaag aagatgagtg tctttcttca aacaaaggga agcaatcaaa
    20701 aagagattga acgctttatc caatctctgc aggtattaga aaatccacaa ttaatagccc
    20761 tttttgaatt gcgttttcag caatataaag aacttataga ttagttagaa atggcaaaat
    20821 aataataatc tcagcaacga ttttcaataa tgttaaaatt tgtttcttca tatttctcca
    20881 ctcctcatta gtagtaactt tattatacca gagaagtaat caaattcacc aaaatcgcaa
    20941 atctgaaatt tctataagaa aaaatatcaa atatgcgatt ttctaaaata agccaatgtt
    21001 cgtgttatac tgtacttgta aagcacttga agcaaatcct aggtcgcaga agtggtttac
    21061 aaatgaagat aattgaagga gtgtaaaaga tgttaaattt acaatttgca gaaacaatgg
    21121 aattgacaga agctgagttg caagatgtta gaggaggcaa cctcgtaaat tctatgggag
    21181 gtggtggaag aagtggtata tctggttggg gcgtcccagg aatttaccct ggttggggca
    21241 atcaagggat gagtcctaat cgtggagctt ttgattggac tatagattta gcagatggat
    21301 tgtttggccg ccgtagaaga taggctctta taggagataa taggatgaag aaaatgaaag
    21361 aagtgaaatt tcacctagca actggcttgt tgattttgac ttattacctc atttttaatg
    21421 tcacatcaga cttagatttt atggttgctt tgtctgataa tatgtactat gtgttccaag
    21481 ttttattggt acttattctg ggaactatag ctacaattgc ttttgtcaaa agtgaacatt
    21541 ggaaagagtg tggtcgtttc cagtttcgtt ggtcttacct gggtgttttc cttctttctt
    21601 ttttcttatt gttcgtgtgg gcaaatctaa caacctatat ctttcctcgt acccagaatg
    21661 gaagtacagt cgtagaagta gccaccaatt taacaggaat tagctatttt gttacgcgaa
    21721 tactttatac tagtattatc gcacctgtat cagaagaggt tgtttgtcgt ggtcttttga
    21781 tgacaagttt atctaaagtt aagagatact atcttgatgt tcttgtttcc gctgccatat
    21841 ttggcgctat gcatgttttg cagtatggtt ggataacgac agatttcata aagtattttg
    21901 gaatgggctt gatattttgt atgatgtttc gctacacccg atccatctat tgggctatag
    21961 ctctgcatgc ttcatggaat agtttcttac tcattgttac tttattggta tttggatatt
    22021 agaaaggtga tatatgaaaa agataatctc acaccgctac tttattatag tttttctact
    22081 agttattgct gaccagaagt tcagtgttct agttttacgc agcgaccttg ttactgggct
    22141 atctgacttt gcctattatc tgtcggatat gatgttgaat tttcttgtgg ttttatttgc
    22201 tcttattgct atgatttggt cggggaaatg gcagaaaatc aatagtagaa agtttaaagg
    22261 atcctatctt ttctattcct tcctagctct gcttgctttt gttgtttgga atttcgttac
    22321 cttttttctt ttcccaccta ctcgaaatga aatttcttat caacatgctg ctccgacttt
    22381 tacaggggct acagcatttt tgatgtattt tttttatcct gtgattgcag gtcccatttt
    22441 tgaagacatg atttatcgtg gattagtgat gactgctctg gaaaaaggaa agaaatgggg
    22501 gctagatgta cttggttccg ctgttttatt tggggtctcg cacattagta atcacggttg
    22561 ggtcttgaca gactttgtct tctatatggg tggaggtctt atatttgcag tcttatttag
    22621 aatgacaaag tcaatttatt ggcctattgg actgcatata gtctacaatg gcattggtca
    22681 gcttttgatg ttactgtaat tttggttgtt agtagtatcg cggtctatcc ttggggaaag
    22741 attcccattt gaacttaaga aggagttgtg atgaaagtat ttcttcaaaa tagagatttt
    22801 aggcaattaa ctatcaacca gtggatttca acgcttgggg atacgatttt ttatctggcc
    22861 ttcctgaatt atgtggcaga tgcatctttt gcccctttgg cgattttact catcacgatt
    22921 tcagaaaccc tgccccaagt tctacaaatc tttctgggag ttttggcgga ttttcaacat
    22981 catcgtgtct tgaaatacac agtcattagt tttgcaaaat ttttgcttta ctctatagtg
    23041 tctttatcac tttcagggca gtctttctcc ttgttgctag tagcatttat ttgtctgatt
    23101 aacctcttgt ctgacacatt gagttatttt tcaggcgcca tgctcactcc gattttcatt
    23161 agaattattg ggcaagacca tctggcagaa gctattggct ttaaacagtc aactgttagt
    23221 ttagtgaaaa caatcagtaa tatcctagga ggagtcttac taggcattct atccatccag
    23281 tttatttcct tactgaacgc tcttaccttt ttaatcgcat ttttaggtat cctcttcata
    23341 aaaactgacc tcttgaaagt agaaaaaacg attagctatc aagaaggact ctctgtaaaa
    23401 tccttttgcc agcatttgct ccaatcatcg aaattgatat ggaatatgaa taaggtgctc
    23461 ttggttttgt ttattatctc tactagtcaa gcagtgataa atgttacggt tcctatttcc
    23521 actctatttt taaggaacca gccctttttg aatttacaaa ctggtcaatc tcttgccttg
    23581 ttagccacac tagaattatc agccctgatt gtcggaagcc ttgtaagtgg ctatctgcaa
    23641 cataccattt ccataaaaac agctctctat gcctcacttg tcatccagtt gcttcttcta
    23701 gtaggatttg ccacagttcg ttttgactgg attctcatct ttagtacctt ggatgccttt
    23761 ttcgcaggtg ttctctctcc tagattgcaa gaactcgttt ttaaacaaat acctgaggag
    23821 tcaatgggag cagttcaatc ctctatcggt gccattacgg ttgttttacc tagcttattt
    23881 acaatagctt tggtaaccat tgctactagc tttggaactc tggcagttag ctttgtttta
    23941 ttgctatttc ttctagttgc ctttgttatg cttctgaata ttcgtgaaag tatttagtgg
    24001 agaatttcta taatatatgt ttgagactgg attgccagtc t
//
LOCUS       DAVHSH010000024        23724 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000024 DAVHSH010000000
VERSION     DAVHSH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.024"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(98..2356)
                     /locus_tag="VVR08_001154"
     CDS             complement(98..2356)
                     /locus_tag="VVR08_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6075075.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGATREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VVR08_001155"
     CDS             complement(2585..2815)
                     /locus_tag="VVR08_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU6075076.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VVR08_001156"
     CDS             3005..3688
                     /locus_tag="VVR08_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6075077.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VVR08_001157"
     CDS             3688..4422
                     /locus_tag="VVR08_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6075078.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VVR08_001158"
     CDS             4576..5433
                     /locus_tag="VVR08_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU6075079.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VVR08_001159"
     CDS             5575..6447
                     /locus_tag="VVR08_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU6075080.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPESMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VVR08_001160"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VVR08_001160"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU6075081.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VVR08_001161"
     CDS             7426..8637
                     /locus_tag="VVR08_001161"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU6075082.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VVR08_001162"
     CDS             8639..9181
                     /locus_tag="VVR08_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU6075083.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VVR08_001163"
     CDS             9197..10006
                     /locus_tag="VVR08_001163"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6075084.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..10877
                     /locus_tag="VVR08_001164"
     CDS             10482..10877
                     /locus_tag="VVR08_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU6075085.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10887..11462
                     /locus_tag="VVR08_001165"
     CDS             10887..11462
                     /locus_tag="VVR08_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU6075086.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11487..11999
                     /locus_tag="VVR08_001166"
     CDS             11487..11999
                     /locus_tag="VVR08_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU6075087.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12653..13363
                     /gene="deoD"
                     /locus_tag="VVR08_001167"
     CDS             12653..13363
                     /gene="deoD"
                     /locus_tag="VVR08_001167"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6075088.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13386..13910)
                     /locus_tag="VVR08_001168"
     CDS             complement(13386..13910)
                     /locus_tag="VVR08_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU6075089.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13963..14199)
                     /locus_tag="VVR08_001169"
     CDS             complement(13963..14199)
                     /locus_tag="VVR08_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU6075090.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(14267..15187)
                     /locus_tag="VVR08_001170"
     CDS             complement(14267..15187)
                     /locus_tag="VVR08_001170"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU6075091.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTVTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15377..15780
                     /locus_tag="VVR08_001171"
                     /pseudo
     CDS             15377..15780
                     /locus_tag="VVR08_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15996..16577
                     /locus_tag="VVR08_001172"
     CDS             15996..16577
                     /locus_tag="VVR08_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6075092.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16574..17851
                     /locus_tag="VVR08_001173"
     CDS             16574..17851
                     /locus_tag="VVR08_001173"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU6075093.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRSLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17869..18531
                     /gene="deoC"
                     /locus_tag="VVR08_001174"
     CDS             17869..18531
                     /gene="deoC"
                     /locus_tag="VVR08_001174"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU6075094.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18518..18907
                     /locus_tag="VVR08_001175"
     CDS             18518..18907
                     /locus_tag="VVR08_001175"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6075095.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            18998..20050
                     /locus_tag="VVR08_001176"
     CDS             18998..20050
                     /locus_tag="VVR08_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU6075096.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20143..21678
                     /locus_tag="VVR08_001177"
     CDS             20143..21678
                     /locus_tag="VVR08_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075097.1"
                     /translation="MPHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRCG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            21671..22729
                     /locus_tag="VVR08_001178"
     CDS             21671..22729
                     /locus_tag="VVR08_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075098.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22732..23688
                     /locus_tag="VVR08_001179"
     CDS             22732..23688
                     /locus_tag="VVR08_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075099.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6894 a         4294 c         5406 g         7130 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag tagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ctacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttgaccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctagagat taaaagagga
     3781 gaagttgtcg ttatcattgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc aacaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaggaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac tattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa tcgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa aaggatgaaa
     5581 gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagtcta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagttg tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagag
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttaatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaattgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgca gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaatcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aattgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctgatat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt agtaagaata aggtcgtcat
     8701 ggcggagctt catcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttctttg cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcaga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatggggg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagattgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtgtgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggaggctacc
    10741 tagctcagat tgcagcggtt gaagattacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttgggatg
    10861 ctaagaatgg tttctgagat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aataatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagcgc gattctttaa gaaacaggct ctacctcaat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa caggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa acttccaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacgg ttctggtaaa gaaattgagt
    11461 gaaaacgtat aatatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaagataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttccagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgacagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 tagaactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaagaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaacaaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aaggaattga ccccacccta aaagtagtgg gaaaaagata
    12421 gttggtctag cgagcatcgc tcactgcgcc caactcctat tttcccttcg ctttttgatg
    12481 ggtttggtat ctttctcaat ataaaatata aaataaagaa aggtagagcg tgtgttttga
    12541 tttgaacacg agcggaaaac tcggaaaata gataatctga ctgaaaaatc aggatttctc
    12601 gtcaggttcc taattttcag tcgttttctt ctcgctcttt gtatcataaa ttatgtctat
    12661 ccatattgct gctcagcagg gtgaaattgc tgataaaatt cttcttcctg gggatcctct
    12721 tcgtgctaag tttattgcgg agaatttcct tggtgatgct gtttgtttta acgaagtgcg
    12781 taacatgttt ggttacactg gtacttacaa gggtcaccgt gtatctgtca tgggaactgg
    12841 gatgggaatg ccatctattt cgatttatgc gcgtgagtta atcgtagact acggtgtgaa
    12901 gaaattgatt cgtgtgggaa ctgcaggttc tttgaatgaa gaggttcatg ttcgtgaatt
    12961 agttttggcg caggcggctg caaccaactc aaacatcgtt cgtaatgact ggccacagta
    13021 cgattttcca caaattgcta gctttgattt gcttgataaa gcctaccata tcgccaaaga
    13081 acttggtatg actactcacg ttgggaacgt tttgtcatct gatgtctttt actcaaatta
    13141 ctttgaaaag aatatcgagc ttggtaaatg gggagtcaag gctgtggaaa tggaagcagc
    13201 agctctttac tatcttgctg cccaatacca tgttgatgcg ctagctatca tgaccatctc
    13261 tgatagcttg gtcaatccag acgaagacac aactgcagaa gaacgtcaaa ataccttcac
    13321 tgatatgatg aaggttggtt tggaaacctt gattgcagaa taattatagc caaaaaggaa
    13381 gccctttatg aattgtagga cttccttttc ttatccagaa attgatctag ctctctctga
    13441 tttcgaagaa tagtgacttt atgtgaatat tcttggcaaa gtttttggta attttctttt
    13501 tgagttttgc tacgcccatc ccaaagaatc catctgataa actcccagtc aaagcgttca
    13561 gggcaatctg ccgccatact ttctctgact tttccacggt atttaagata acgcttaaag
    13621 gctctaaaga gacaggtcaa tggcaaaaaa ttgagaaaga tgatttggtc agcttcttgc
    13681 attcgttctt ggtagtagca ccaagaataa ttaccatcga tgacccaagc tttatgcttg
    13741 gtgagaaagt tttttatctc ggttaacatc cattcgcagt cactgtcttg ccaaccaggt
    13801 tgaaattgga gtgtgtccat gtgcagtttt ggaatggagt agtagttaga taacttttct
    13861 gctagagttg acttaccaga accagaatat ccgataattg tgattttcat tttctacctt
    13921 ttcctatttg gagacaaaaa aacagcctct atggactgtt tcttatttag caagtttagt
    13981 tgaaagacga gctttatcgc ggcttgcttt gtttttgtga atcaaacctt tagtttctgc
    14041 tttatcgata gctgagctag cagcacggaa aagttcttca gatgggtttg cttcgaaagc
    14101 ttttatagca gtacgcatag ctgatttttg agctgagttc ttttcgtttt gtttaacgtt
    14161 caattcagcg cgtttgatag ctgatttaat gtttgccaat gttcttacct ccatatttac
    14221 taactatacc attatatatg aaaacttacg ttttgacaag ggaaaattac ttttttaagt
    14281 aaatttcatc gatttcatgg ttcttgcttt tatgaagaat cacttctgca cgatttctgg
    14341 ttggttcaat ataattttgc agatttgtga gattgatact gatccagacc tgatgggcaa
    14401 aggactccac ttccccaatc ggcatctgag taaaacgata atagtagcta tcagggtcgt
    14461 tttgggctag gctcagcatc ttcaagaaac ggtccagata ccaactttca atatcatcca
    14521 ctccagcatc tacatagatg gaaaagtcaa agaagtcagt gatatagaga cgatcgtttt
    14581 gtggattttg aaagacatta attccctcaa caattacaaa atcagcagct ttgacacttt
    14641 gtttcttttc gggtacgatg tcgtaaactt catgagaata gacaggaata tctacatctt
    14701 gtccattttt gatgcggtcc aagaagttga gaagagcttc catatcatag ctttcaggaa
    14761 atcctttacg atttaaaatc ccctgctcaa tcaaggtttg attgggatag agaaaaccat
    14821 cagttgtaac caactcaacc gtagcatctg taaccgtacg ggacagtagg atttgaagta
    14881 ggcgactggt tgtggatttt ccaacggcaa cactcccaga aaccccaata ataaaaggtt
    14941 gagatttact ttcacgttgg aggaaaattc cttttgaaaa ggctaaatct tccttagttc
    15001 gcttgtaaat ctgaatcaga tgagccaagg ggagatagat atctgtaacg tcttggagac
    15061 tgatttggtc attaaaactc ttgatagatt ccaattcttc ttctgtcaaa ggaggtgttg
    15121 tctttcgatg taaagattgc caagtctggc ggctgatttt ttcaaaatgt aaaaattcgt
    15181 tggtcatttg ttttccccta gatattttgt ctatcatacc ataaaaagct aaaaaaataa
    15241 agcggtttct tgaatgtggt aagtcaatgg tatatagtat aagtgatcaa tttattgatg
    15301 aaataggaga tagattctac tgatttataa gcttataaag ggggcttttt agttcacaac
    15361 ttataggagg tgtactatga aaatcttaaa acgttacata ttggaactct gttttatttt
    15421 aagttttgct ttacctttta taaaaggaac caatgcagat aatggtagat gctttgtgga
    15481 aacctattac ggttttactt ttttgatgga acatgctatt gtaacagctg tctttatctg
    15541 ttcgttctta attgctttct tactaaaaaa cgatggacga aatggattgc tgcgggtagt
    15601 tattgctttt tagtcctacg gattgcgaca gagggttatt tcttccacat gtcactagaa
    15661 gatttgatac gactttggac aagtttggaa atcctgacac aaacgtatca gttgggcttt
    15721 tatctaaaca ttttgttagg aattttgttg ataataaagt attttaaggt taagcaatag
    15781 aaataataat ctgcctgatt atagatgata aactttttgt ttttatctgg actgtgatat
    15841 ttatagttct aaatggttta ttatttataa gtgttgaaag agattgaaga aaatggcttc
    15901 gtgacttgct ttcttcggtc tttttcgttt tattatcaat ttgtaaacga tttacaattt
    15961 gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta ctatgcagaa aatcctgacg
    16021 ctgctcacga cattcatgag ttgagagtgg acttgttggg agaaaaaatg acttttttga
    16081 cagatgcggg tgtttttagc aagaaaatgg ttgactttgg aagtcaactc ttgctcaagt
    16141 gtctggatgt caaccaagga gagacagtcc tagatgtagg ctgtggttat ggtccattag
    16201 gtttgtcctt ggtcaaggtt tacggagttc aggcgaccat ggttgatatt aacactcgtg
    16261 ccctggattt agctcagaga aatgctgaaa aaaataatgc aaaagcgacg atatttcaat
    16321 ctaatattta tgcaagagtt caagggcgat ttgaccatgt catttccaat cctcctatcc
    16381 gtgcgggcaa gcaagtcgtt catgaaatca tcgagaaaag taaagatttc ttggaaattg
    16441 gtggagattt gaccatcgtc atccagaaaa aacaaggagc tccaagtgcc aaatctaaga
    16501 tggaagatgt gtttggcaat tgtgaaatcc ttaaaaaaga caagggatac tatatcctta
    16561 gaagtgtgaa agaatgagag cagttgattt aatccaaaaa aaacgagacg gtcaagaact
    16621 gacttcaagt gaaattgaat ggctgataga aggctatgta tcaggaactg ttcctgatta
    16681 tcagatgtct gcctttgcta tggctgttta ttttaaagga atgacgactc gagaaatctc
    16741 tgatttaacg atgaatatgg ttaagactgg gcaagagttt gacctgtcag ccattgatgg
    16801 tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat aaggtaacct tgattttagc
    16861 tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg agtggtcgta gtcttggcca
    16921 tacaggcgga acaattgata aattggagtc cattaggggc tatcaagtag aacgtagtca
    16981 agaggatttt attcgtcagg ttcaggatat tggagtatct gtcattgggc aatcagacca
    17041 gctggtcaaa gcagataagc ttctctatgc ccttcgtgat gtgaccgcaa ctgtcgacac
    17101 gattcctttg attgcgagtt cggtgatgag caagaaaatt gcggcagggg cggatgctat
    17161 tttgctagac gtgactgtcg gtgagggtgc cttcatgaag acggttgatg aggcgcgtga
    17221 gttggctcaa actatggtag atcttggtaa ggttgttgga cggaagacag tagcagtgat
    17281 tacggatatg agccagcctt tgggacgagc gattggaaat cgtctggaaa tccttgaagc
    17341 attggagatt ttgcaaggtc aaggacgtca ggatattacc cactttattt gtgaattggc
    17401 tcaaattatg cttggtttgg caaatgttaa caaaactgtt gaagaagttc gccaacatct
    17461 tgaaaatggt caagcactgg ctaagtttga ggaaatggtg caagcccaag gtggagactt
    17521 ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg gaaatccctg ctcaggaaac
    17581 gggtgtcatt tcagctcttc cagctatgga ctttggtctt tatgccatga ggctgggtgc
    17641 tggtcgtgca gttaagtctg atgtcttgga ctatgaaaca ggaattgttt ttgaaaagaa
    17701 gattggagac tccgttcaaa agggtgaaat tgttgcaaaa gtatacacaa atgaaaaaat
    17761 tccacctcaa ctagttacag atttccaaaa atgtgttaaa ataagtgatg aagtgaaaaa
    17821 aatccgtgaa attgtagaaa tcatctccta aatggaggga aaaccgaaat gaaattaaat
    17881 aaatatatag atcatacgct tttaaaacaa gatgcaaaga aaaaacaaat tgatagtttg
    17941 ttgtctgagg ctagagagta tggctttgcc agtgtttgcg ttaatccgac ctgggttgaa
    18001 catgctaaaa aaggacttga aggcacagat gttaaggttt gcacagtagt aggtttcccc
    18061 ttgggagcaa caacttcaac tgtgaaagct tttgaaacaa aagaagctat ccaaaatggg
    18121 gctgatgaga ttgacatggt aatcaatgtt ggggctctca agtcaggtga tttggccttg
    18181 gttgagtcgg atattcgtgc agtagtggaa gcaagtgggg acaagttagt gaaagttatt
    18241 attgaagctt gccttctgac agaccaagaa aaagttttgg cttgccaatt agcccaaaaa
    18301 gcaggagctg actttgtcaa aacatctact ggcttttcaa ctggtggtgc tacgatagca
    18361 gatgttagat taatgcgtga aacagttgga cctgatatgg gtgtcaaggc cgccggtgga
    18421 gctcgttctt atgcagatgc tcttaccttt gtcgaagcag gtgcgacccg tatcggaacg
    18481 tcagctgggg tagctatttt aaaaggagaa ttggcagatg gcgactactg agttgattga
    18541 actggcaatt gaaaccagca aacatgccta tgtcccctat tctcactttc ctatcggagc
    18601 agttttagta gccaaagacg gaagtgttta cacgggagtg aatatcgaaa atgctagcta
    18661 tcctttgacc aattgcggtg agagaacagc tatttttaag gctatatctg aaggccaaag
    18721 agaattttca gaattgattg tctatggtca aactgaaaaa ccgatttcac catgtggtgc
    18781 ttgtcgccaa gtaatggtcg aattttttga acaagattta aaagtgaccc tagtcgcaaa
    18841 agataaatcg acggtcgaga tgacggtcgg ggagttactt ccatactctt ttacagactt
    18901 aaattagtct gagtcgctct ttgagtggca agggtctttg tgaccaatca atccatactt
    18961 gcaacatcgt tgcacatctt atttaggagg ttcagtaatg aacaagaaac aatggctagg
    19021 tcttggccta gttgcagtgg cagcagttgg acttgctgca tgtggtaacc gctcttctcg
    19081 taacgcagct tcatcttctg atgtgaagac aaaagcagca atcgtcactg atactggtgg
    19141 tgttgatgac aaatcattca accaatcagc ttgggaaggt ttgcaagact ggggtaaaga
    19201 acacaatctt tcaaaagata acggtttcac ttacttccaa tcaacaagtg aagctgacta
    19261 cgctaacaac ttgcaacaag cggctggaag ttacaaccta atctttggtg ttggttttgc
    19321 ccttcacaat gcagttgaag aagcagctaa agaacacact gacttgaact atgtcttgat
    19381 tgatgatgtg attaaagacc aaaaaaatgt tgcgagcgta actttcgctg ataatgagtc
    19441 aggttacctt gcaggtgtgg ctgcagcaaa aacaactaag acaaaacaag ttggttttgt
    19501 aggtggtatc gaatctgaag ttatctctcg ttttgaggca ggattcaagg ctggtgttgc
    19561 gtcagtagac ccatctatca aagtacaagt tgactacgct ggttcatttg gtgatgcggc
    19621 taaaggtaaa acaattgcag ccgcacaata cgcagccggt gcagatattg tttaccaagt
    19681 agctggtggt acaggtgcag gtgtctttgc agaggcaaaa tctctcaacg aaagccgtcc
    19741 tgaaaatgaa aaagtttggg ttatcggtgt tgaccgtgac caagaagcag aaggtaaata
    19801 cacttctaaa gatggcaaag aatcaaactt tgttcttgta tctactttga aacaagttgg
    19861 tacaactgta aaagatattt ctaacaaggc agaaaaagga gaattccctg gcggtcaagt
    19921 gatcgtttac tcattgaagg ataaaggggt tgacttggca gtaacaaacc tttcagaaga
    19981 aggtaaaaaa gctgtcgaag atgcaaaagc taaaatcctt gatggaagcg taaaagttcc
    20041 tgaaaaataa tggatggaag tcattttgtc tcagtaaagc ttgctactag acaaactagc
    20101 aagttttatt gaaataaaat aagactctga aaggaagagc acatgccaca cgaaaatgtc
    20161 attgagatgc gtgatattac caaggtgttt ggtggatttg ttgccaacga caaaatcaac
    20221 ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc tggtaagtcc
    20281 acgctaatga acatgttagc aggccttctt gaaccaacca gtggtgaaat cgcggtcaac
    20341 ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat cgggatggtt
    20401 caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat tttaggtagt
    20461 gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat caaggctctt
    20521 tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat ctcagttgga
    20581 gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg gggctgatat ccttatcttt
    20641 gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc tattatgaaa
    20701 aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga tgaaattcgc
    20761 gcagtttctg accgtgttac agttatccgt tgtgggaaat caattgaaac cgttgaaatt
    20821 gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt ttcctttaaa
    20881 acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga tttggtggtc
    20941 aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg tgctggagag
    21001 attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca agccattaca
    21061 ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat tgtaggcttg
    21121 cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg tcaccgtgat
    21181 ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta ctataaagaa
    21241 ccacatagta aaaatggaat tttgaattat tcaaatatta cttcttatgc taaaaagctg
    21301 atggaagagt ttgatgttcg cgctgccagt gaattagttc ctgcagctgc actctcagga
    21361 ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga tctccttatc
    21421 gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca caaacgcttg
    21481 attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt ggatgagatt
    21541 ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg tattgtatca
    21601 ccagaaacaa ccaataaaca aggacttggt gtcttgatgg ctggtggaaa cttgggaaag
    21661 gagaagagtg atgtctaaaa aattacaaca aatttcggtt cccttgattt ctgtattcct
    21721 aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta tttggggcta
    21781 cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa tcttccgtgc
    21841 tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag ctggtttctt
    21901 taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt ggtttgccct
    21961 gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga ttgccttgat
    22021 tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag ggacgtcaga
    22081 ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg cctttatcca
    22141 tgctttccct aaagacttca tgcaaagtac agattcgacc attcgtgttg gggctaatgc
    22201 aacctatcag acaccttggt tagctgagtt gactggtaac tcacggatga atattggtat
    22261 tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa caactcttgg
    22321 ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg gtatttctgc
    22381 caagcggact attattctat ctatgattat ttcaggtgcc ttggcaggtc ttggtggagc
    22441 tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat tagctatcgg
    22501 atttaacgga atggcggtta gtttgcttgc ggccaactca ccaattggta tactctttgc
    22561 agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg cgcaggtacc
    22621 atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg ttcattacct
    22681 tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa gatgtctatt
    22741 ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc tctcatcttt
    22801 acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg ccttgaagga
    22861 attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc agaacaattt
    22921 ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag tgttttctct
    22981 atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag cggtacggta
    23041 ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta taacaaagga
    23101 caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt ggcaaatatc
    23161 ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct ggcgattgcc
    23221 ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg tctccgctct
    23281 gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa gatgagatat
    23341 ttaggggtta ttatttcagg ttttctaggt ggaattggcg gagcgattta tgcgcaatca
    23401 atctcagtta acttctcagt gacaactatt gttggacctg gatttatcgc ccttgctgcg
    23461 atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt ctttggactt
    23521 tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt gccagcggtt
    23581 tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt ctttggaaaa
    23641 gcagtcgcac caaaagcaga tggtatcaac tacatcaaat caaaataagc atacaaaaaa
    23701 acgtcagtcc aatgactgaa ctgc
//
LOCUS       DAVHSH010000025        23316 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000025 DAVHSH010000000
VERSION     DAVHSH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.025"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            187..2340
                     /gene="blpA"
                     /locus_tag="VVR08_001180"
     CDS             187..2340
                     /gene="blpA"
                     /locus_tag="VVR08_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEU6075100.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2351..3712
                     /locus_tag="VVR08_001181"
     CDS             2351..3712
                     /locus_tag="VVR08_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU6075101.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            3769..3897
                     /gene="blpC"
                     /locus_tag="VVR08_001182"
     CDS             3769..3897
                     /gene="blpC"
                     /locus_tag="VVR08_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU6075102.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(3968..5308)
                     /locus_tag="VVR08_001183"
     CDS             complement(3968..5308)
                     /locus_tag="VVR08_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6075103.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLAFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5322..6059)
                     /locus_tag="VVR08_001184"
     CDS             complement(5322..6059)
                     /locus_tag="VVR08_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075104.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6064..6402)
                     /locus_tag="VVR08_001185"
     CDS             complement(6064..6402)
                     /locus_tag="VVR08_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075105.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6679..7008
                     /locus_tag="VVR08_001186"
     CDS             6679..7008
                     /locus_tag="VVR08_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6075106.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7176..8225)
                     /locus_tag="VVR08_001187"
     CDS             complement(7176..8225)
                     /locus_tag="VVR08_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075107.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8222..8953)
                     /locus_tag="VVR08_001188"
     CDS             complement(8222..8953)
                     /locus_tag="VVR08_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075108.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLTPYSGSININGLTLQEDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVTFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9021..9431
                     /locus_tag="VVR08_001189"
     CDS             9021..9431
                     /locus_tag="VVR08_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6075109.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9441..9728
                     /locus_tag="VVR08_001190"
     CDS             9441..9728
                     /locus_tag="VVR08_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075110.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10095..11231)
                     /gene="dnaJ"
                     /locus_tag="VVR08_001191"
     CDS             complement(10095..11231)
                     /gene="dnaJ"
                     /locus_tag="VVR08_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU6075111.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11446..11850)
                     /locus_tag="VVR08_001192"
     CDS             complement(11446..11850)
                     /locus_tag="VVR08_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU6075112.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(11861..13684)
                     /gene="dnaK"
                     /locus_tag="VVR08_001193"
     CDS             complement(11861..13684)
                     /gene="dnaK"
                     /locus_tag="VVR08_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU6075113.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14164..14688)
                     /gene="grpE"
                     /locus_tag="VVR08_001194"
     CDS             complement(14164..14688)
                     /gene="grpE"
                     /locus_tag="VVR08_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU6075114.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(14715..15749)
                     /gene="hrcA"
                     /locus_tag="VVR08_001195"
     CDS             complement(14715..15749)
                     /gene="hrcA"
                     /locus_tag="VVR08_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU6075115.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(15913..16422)
                     /locus_tag="VVR08_001196"
     CDS             complement(15913..16422)
                     /locus_tag="VVR08_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU6075116.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRRRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17029..19362
                     /locus_tag="VVR08_001197"
     CDS             17029..19362
                     /locus_tag="VVR08_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6075117.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLMYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVKKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19375..20838
                     /locus_tag="VVR08_001198"
     CDS             19375..20838
                     /locus_tag="VVR08_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6075118.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGEGVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            20838..22406
                     /locus_tag="VVR08_001199"
     CDS             20838..22406
                     /locus_tag="VVR08_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6075119.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            22463..23260
                     /gene="psrA"
                     /locus_tag="VVR08_001200"
     CDS             22463..23260
                     /gene="psrA"
                     /locus_tag="VVR08_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU6075120.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT         7495 a         4598 c         4304 g         6919 t
ORIGIN      
        1 tgaattgcca tcgaaacgtc ttgaattagc ttttttattt caagccacct ctaaatgttt
       61 aaaaaaaata atttctaatc acttttttac cattcaggaa gttttaatga ctattcaaga
      121 tttcataaaa tatgaactta gttttatggc ataatatacc tatccactat atgaaaggaa
      181 ttgccaatga cttcttataa acgtacattt gttcctcaaa tagatgcgag agactgtggt
      241 gtcgctgcct tagcctcgat tgctaaattc tatggttcag atttttctct agctcacttg
      301 agagaacttg caaagaccaa taaagaaggg acgactgctc ttggcattgt aaaagccgct
      361 gatgaaatgg gctttgaaac aaggcctgtt caagcagata aaactctctt tgacatgagt
      421 gatgtcccct atccatttat cgttcacgtt aacaaagaag gaaaactcca acattactat
      481 gttgtctatc aaacaaagaa agactatctg gttattggtg atcctgaccc ttctgtaaaa
      541 atcactaaaa tgtcaaaaga acgctttttc tctgaatgga ctggagtagc tatttttcta
      601 gctcccaaac ccagctatca accccataaa gataaaaaga atggtctact aagcttcctt
      661 cctctgattt tcaaacaaaa atctctcatt gcttacattg ttctctcaag cttattggtc
      721 actattatca atataggtgg ttcttattat ctccaaggaa tcttagatga atacatccca
      781 aatcagatga aatcaacttt aggaatcatc tcagttggtc tggttatcac ctatatcctc
      841 caacaagtca tgagcttctc cagagattat ctcctaaccg ttctgagcca gagattaagc
      901 attgatgtga ttttatccta tattcgccat atttttgaac ttcccatgtc tttctttgcg
      961 acacgtcgta caggagaaat catttcacgg ttcacagatg ctaactctat tatagatgcc
     1021 ttggcttcta ccattctttc tcttttcctg gatgtttcta ttctgattct tgtagggggc
     1081 gtcttactgg cacaaaaccc taatctcttc cttctttctc ttatttctat tcctatatac
     1141 atgttcatca tcttttcttt tatgaagcct ttcgaaaaaa tgaaccatga tgtcatgcaa
     1201 agtaattcta tggttagctc tgccattatc gaagatatca acgggattga aactataaag
     1261 tcgctcacga gtgaagaaaa tcgctatcaa aatatagaca gcgaatttgt agattatttg
     1321 gaaaaatcct ttaagctcag taaatattct attttacaaa caagtttaaa gcagggaaca
     1381 aaattagttc tgaatatcct tatcctatgg tttggcgctc aattagtcat gtcgagtaaa
     1441 atttctatcg gtcagctgat tacctttaac acactttttt cttactttac aactcctatg
     1501 gaaaatatta tcaacctcca aaccaaactc caatctgcga aggttgctaa taaccgtttg
     1561 aacgaagtct atctagtcga atctgaattt caagttcaag aaaaccctgt tcattcacat
     1621 tttttgatgg gcgatattga atttgatgac ctttcttata agtatggttt tggacgagat
     1681 accttaacag atattaatct cacgattaaa caaggagata aggttagcct agttggagtt
     1741 agtggttctg gtaaaacaac tttagccaaa atgattgtca atttctttga accctacaaa
     1801 ggacatattt ccatcaatca tcaggatatt aaaaacattg ataaaaaagt cttgcgccgt
     1861 catattaatt acctaccaca acaagcctat atctttaatg gctctatatt ggaaaactta
     1921 actttgggcg gtaatcatat gattagccaa gaagatattc taagagcttg tgaattagct
     1981 gaaattcgtc aagacattga aagaatgcct atgggctatc aaactcagct ctctgatgga
     2041 gctggtctat caggaggaca aaagcaacga atagccctcg ctcgtgctct tttaactaaa
     2101 tctcctgttt taatactaga cgaagctact agcggtcttg atgtcttgac tgagaaaaag
     2161 gttatagata atcttatgtc tctaactgat aaaaccattc tctttgtagc ccatcgtctc
     2221 agtatagccg aacgaaccaa ccgtgtcatt gttcttgacc aggggaaaat cattgaagtt
     2281 ggtagtcacc aagagttaat gcaggcgcaa ggtttctacc atcatctatt caataaataa
     2341 ggagaatgtc atgaatccta atctttttag aagcgtcgag ttttatcaga gacgttacca
     2401 taactatgcg acagtgttaa ttatacctct ttcattacta tttactttca tcttgatttt
     2461 ctcccttgtt gccacaaaag aaattactgt tacttcccaa ggagaaatcg cccctacaag
     2521 tgtcattgcc tccattcagt caaccagtga taatcctatc ctagctaatc atttagtggc
     2581 aaatcaagta gttgaaaaag gggacttact catcaaatac tctgaaacaa tggaagaaag
     2641 tcagaaaact gccttagcaa ctcaattaca aagacttgag aagcaaaaag aaggacttgg
     2701 aattttgaaa caaagcttag aaaaagcgac tgatcttttt tctggcgagg atgaatttgg
     2761 ctaccataat acctttatga attttactaa acaatcccat gatattgaac tgggtatcac
     2821 aaagactaac accgaagttt caaatcaagc taatctttcc aatagcagtt catcagctat
     2881 tgaacaagaa attacaaaag ttcaacaaca aattggagaa tatcaagagt tgagagatgc
     2941 tatcataaat aacagagcac gcttaccaac tggcaatccg caccagtcaa ttttgaatcg
     3001 ttatcttgta gcctcacaag gacaaacaca aggaactgca gaggagccat ttttatctca
     3061 aattaatcaa agtattgcag gtcttgaatc atctatcgca agcctcaaaa ttcagcaagc
     3121 tggtatcgga agtgtagcaa cttatgataa cagtttagca accaaaattg aagtactccg
     3181 cactcagttt ttacagacag cctcacagca acaactaact gtggagaatc aattaacaga
     3241 attaaaagta caactagatc aagccacaca gcgtttggaa aacaatacct taacctcccc
     3301 aagtaaaggt atcgttcatc tgaacagcga atttgaaggt aaaaatagaa ttccaactgg
     3361 tacagaaatt gctcaaatat tccctgtcat cacagataca agagaagtac taatcactta
     3421 ctacgtatct tctgactatc tacctctact agataaagga caaactgtaa gattaaaact
     3481 ggagaagatt ggaaatcacg gcaccaccat catcggccaa cttcagacaa ttgatcaaac
     3541 tcctaccaga acagagcaag gaaatctctt taaattaacc gctcttgcaa aactatctaa
     3601 cgaggatagt aaactcatcc aatatggctt acaaggtcgc gtcactagtg taactacaaa
     3661 gaaaacatat tttgattatt tcaaagataa aattttaaca cattctgatt aattttcaga
     3721 taacactcta taactattta ttatcttatc aaaaaggaga atcataacat ggataagaaa
     3781 caaaacctaa cttcatttca agaactaaca actaccgaac tcaaccaaat tacaggtgga
     3841 ggattgtggg aagatttatt atataacatt aatagatatg ctcattacat cacataagaa
     3901 cttcatcatc caatacaact ataaaaaaat aagaccgaga aacaagtact ctcggtctta
     3961 tttttcatca ttctgtatgt atcacagtaa gtacctgacg aaagacttga ttttgacagg
     4021 tggtatttag actggtatta ggatggcttt ccacaatctt catgacggta tagagaccaa
     4081 ctcctctctc ctccccttta gaactggctc caaaggagaa gatttcagaa atatcgatgc
     4141 cctcttcttt gatggagttt tcgatgataa aggtctcctg tgctccattt tttaaaaagg
     4201 cgattgaaac atgaggttga ctagcttcca cactggcttc aatagcattg tcacaaagga
     4261 tagacacaat ggttagaaaa tcaagtagac tcatcccctc gacctgaatc tcctcaggaa
     4321 cttcgacatt aaagacaatg ttcttatctc tggcttttaa aaatttccct gctagaagac
     4381 ttttgagggc tttatcacga atatttacca atctgcccag gtcatattta ttgttctgca
     4441 atttctgact ggaatccttt aagacggagc catagacctc ttttatctgc tccatatcct
     4501 cctcttcaat gcccagacgt aagctagtca agaggttggt ataatcatgg cgaaaactcc
     4561 gtacttcctt gtaaagctcc tctatatgcc gactatagcg ttccatatct ctatagcgca
     4621 gggcctgctc ttgttccaat ctctcataga gtttttcctt caaataggta tccaatttct
     4681 tgataacccc cataaaaaag agtaggtaaa agactaggat gagatggcga acagtctttg
     4741 attgaatact ttgttcatat tcaaaaaaag acagactttc catgactaga tagtagccac
     4801 ccattatcca gttaatctga gtcagggact tttgaaaggc tttatcgaga atctcctttc
     4861 tcaagctagt aaaatcgtag tccaaccatt tcaaaaaagc tagagaaatg aagaaattga
     4921 aaattattat acataaccca gtaaatgagt agccatcata tacttgccct tgtcccaaaa
     4981 atggaagcac aaaataggag actcctctat aaaagagatt caccaatatc attggaaaga
     5041 gaccataaaa gaaaaggagt tttttaggaa gccctctcaa taataagaaa gataagccta
     5101 tgccgtacaa gggttccata aaataagata ggtaaacatt tcctactata tagctaatca
     5161 tcacaaaaac aaaggccaac agtatcttaa aaagaaaggc cttaaaaatc ctctcgaaag
     5221 caagatcaat tccatccacc ttaaagaaga tgacaatttc tagtccatta gtaacaagtg
     5281 tatacaacaa tatccaagca atgttcataa attctcctag ctcagtgtaa tttattgatg
     5341 gcctcagaca cttccctgac cttataacgg gcgattagac aacttccacc attgggaaag
     5401 aaaagcagtt tttctttctt atccaaatgc accacatttg caggattgat gagaaaagag
     5461 cggtggcact gcaagagacg gggctcctgc ttgaaaacct cctctaaact cgctgtaaat
     5521 tccagcctgt ctgtcttggt atagagaata acacgatggg ctctgggcga cgtttcgaga
     5581 tagtaaacct ctttaaaagg atactgaaat tgggcaaatt ttgatttaaa gtaaaagcaa
     5641 tcttccgcca gacttttact atcttgacta ttggcataga ggagggctgt ctcgatccga
     5701 gattcaaact cctctgctga caaggcctta tcaatgtagt ccaaagcaga cacttggtag
     5761 cgaaaagaca ggggcataaa ctccgagtga gtcgtcacaa agacaatcag ggcataagga
     5821 tcccgatccc gaatctttct agccacttcc agtcccttca tctcttcatt tcgaatctca
     5881 atatccaaaa agaatagctg atgggccccc ttctcatgca cttcagccag cagttggtcc
     5941 ggcttgccaa atacctcaaa agagctagga atgatatgat gtgctttcaa aagtttctca
     6001 atcgtcgttt caattctagt ctgttgggaa aaatcatcct ctaaaacaaa tattctcatc
     6061 ttcttactct ccctctttca accatttttg acgaatttct ctatagcgac gtctggcata
     6121 cttgacagcg tattgacctt cttctccgag aaaaaggatt ctttcttgaa aatcaatcga
     6181 ttttaattta tcaagattaa ccaaacaatt tcgatgacat ctcatcaagg tttccccaca
     6241 ttggttctca agattactta aattttgaag catattaaaa ctagcttctt ctgtaacaat
     6301 ctgtacggta tgggctttag ttggatgtgt ttggatatag tagatatcgt cgatgtttac
     6361 tttatagact gttttctgcg tctgaataat catatatttc attggattct cctcctaaga
     6421 aaagaataac agaaaaggtc tagcccaagc acacccaatc ctaaacagtc tttgaaaact
     6481 cctaaaagga ttatttttct acaacatcat gatgagctta caactatttt atcataaaat
     6541 tcactcagcg caattcaaga catttcaatg acaattaaag atttgaataa aaaaaaagaa
     6601 ttaaaaatga taaactaaca gtatcaaaac acagttgcca gaagtaagac tggcacccag
     6661 attaaaggag gcattcccat gacagataca gaccccatca aaagagctca tactttgatt
     6721 actgacttaa acaaagccta ccaagcatgc aaacaggcaa gcgctgacga cgtccgcttt
     6781 caggagcaat taaactctat tcttggtttt ctagccaagg ctgaaacagt ggataatcga
     6841 ttcttgattg aactagaaaa attttaccag acttccagtc ttctcatggg actcagcgct
     6901 cttgatccag atgctccaac tcgcgccgct tggcgggcct atgaccgctt ccactttgac
     6961 caagtcaaga ccaagttaat actcaatgaa aatcaaagag caaactagga agctagccgc
     7021 aagctgtact tgagtacggt aaggtgacgc tgacgtggtt tgaagagatt ttcgaagagt
     7081 ataagtctct acggaccaac cattatcctg tagtaacaaa aaagaagctg agacagactg
     7141 aactcaactt cttttttagt gtcgtatcag caatgttagt cctgcatctg acgttttacc
     7201 tgataaggca aatacaagac tagtaaaacc aaaccagctc ctagtaaggc tagaagggcc
     7261 agtttttctt ggaaggtaat caacccaaca actaattcca caagtaaaac aaaactggtc
     7321 aatcctcgaa ctacctcctg taagcctttt tccttttgcc ccttgtccag cggaaagagt
     7381 tgggtcaaat actggtagtc aaaggcatga tagagggcca gcaactggaa gagcaagagg
     7441 tagttaaaga gaactaccac tgctgtcgca atccaagctt gctcgataaa aacctgcgcc
     7501 agtacggaaa gtaatagaag acgaagactg agagcaaaga ggtcgccatt tcgcagataa
     7561 gaacgcagat agagattttg ccaaatcttc ccaggcacct tctgaacagc ctttaagata
     7621 aagtccagat aggcacgacg cttaacgctg tttgaaattc ccttgacctg cgtaaagagg
     7681 gcaaagaaac gaagcaagac ttgcttacgc ttgctttctt gagaaataac atagtcccag
     7741 tccagtccag tttcagtgaa aaatttgctg gccttttgac gaaagtggaa atattttcct
     7801 acccccaata aaagcacata gagcagaaaa actggcaagc cataacccat tgctaaaaat
     7861 aaaggcgcaa ataacagcaa gaaaagggtc tgtacaaaga gccaaaagac tagggaaatg
     7921 ccagtttgac gcttgagatg gagcttgatt tcctcttctc caactaagag aaagagcttg
     7981 tctggagcct ccatataggt ggcaattcct ccccaaagta aaagtaaaac agacgtaatt
     8041 cctacaaaca aaaggatagg ccaatgattt tcaggaaaat gttgtaagag ttgactgtac
     8101 tggtaggcta gaaagcccaa caggacaagc aggaacaaga caaagtggtc attgagcaca
     8161 tagcgcagat aaccaagaca ctccttacga aaggcctgct ttctctttaa aaacaagtct
     8221 ttcatagatc ctcctctttg gtcagagcca agtaaatatc attcaaacta gcctcaggca
     8281 tatcaaaggc ttcacgtagt tgcaggagat tgcctttggc acgcacctct cccttgtgaa
     8341 gaatgacaaa ggcatcacac atcttctccg ccgaatccag cacgtgggta ctcatgagaa
     8401 tagacttgcc cttttgcttc tccacttcca aaagctgaat caaatcagaa atagccagcg
     8461 gatcaagacc aaggaaaggc tcatccacga tgaaaagact tggatccacc acaaaagcac
     8521 agataatcat gaccttctgc ttcatccctt ttgaaaaatg aacagggaac cagtctaatt
     8581 tctgttccaa acggaacatt tttaacaagg gctctactcg ttcgaaagtc actttttgct
     8641 caataccgta agccatagca accgtttcga tatgctctct gagagtcaat tcctcataca
     8701 gactaggcgt ctcaggaatg tagccaattt gcttgcggta gctcgttgca tcttcttgca
     8761 gggtcaagcc attaatattg atggaaccac tataaggtgt caacagaccg ataatctcat
     8821 taatggtcgt cgatttacca gcaccattga gaccaatcaa accaaccagc tgcccacttt
     8881 caacggtaaa ggacacatct ttcaaaacag gaacatgaac atagccacct gtcaggtttt
     8941 taatttctaa catattttct ccaaatctgg tataatgtag ctatattata tcaaaattca
     9001 gtacagtaga ggtagatttt atgtcagatt gcattttttg taaaatcatc gcaggggaaa
     9061 ttcctgcttc aaaagtatat gaagatgagc aggtccttgc ctttcttgat atctctcaag
     9121 taacactagg acacaccttg gtcgtgccaa aagaacacta tcgcaatctt ttggagatgg
     9181 atgctacgag cgccagccaa ctctttgccc aagtaccaaa agtagctcaa aaagtcatga
     9241 aagtcactaa ggctgctggt atgaatatca tttccaactg tgaagaagtc gctggtcaaa
     9301 cagtttttca tactcacgtt caccttgtgc ctcgctacag tgctgacgat gacctcaaga
     9361 ttgattttat cgcccacgaa ccagactttg acaaacttgc tcaagtcgct gaaaccatca
     9421 aaaacgctta aggagttgct atgaaattat ccaacctact gctatttgca ggagctgcag
     9481 ccggaagtta tctggttaca aaaaatcgcc aaaccatcac agatgaagtc ttgaatacca
     9541 ctgaccgcgt tcaagctatc aaagacgatg tggatattat ccaaaatagc ctgcaaatca
     9601 tcgaccagca aaaagaactt atcaaggaat accaagaaga cttgacttac aagtttaagg
     9661 tcttggaaaa ggatatccag actagactag ctgtgataaa agaaatgcag ggaactgaag
     9721 ataagtaaaa agagcccccc ggctcttttt taaaacgtaa acaagttata gtgaattgaa
     9781 tttagaatag cacatcatag tttctaaagc attgttagag attactttaa aatcctctta
     9841 tcaatttgtt catattctat ttcaatctac tatatatatc ccatcaacta tgcatcataa
     9901 tttaggtaac tcatactcaa taaaaatcaa aaagcaaact agaaagctag gcacagactg
     9961 ctcaaaacac cgttttaagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
    10021 tgaggttgta gatacgactc acatatatac ggcaaggcaa cgctgacgtg gtttgaagag
    10081 attttcgaag agtattattc tccatcaaag gcatctttta tatggtcaaa gaagcctttt
    10141 ttctttggat ttactttcaa gtcaccagca gccgcgaatt ctttcaaggc tactttttgg
    10201 cggtcgttca agcctgtcgg tgttacgaca ttaacagtaa cgtattggtc accaactgca
    10261 ccgccacgaa ggctcggtgc ccccttacta cgtaggcgga atttcttacc agtctgagtt
    10321 ccctctggaa taaccaattc aacatcaccg tgaacagttg gaatatctac tgtatcacca
    10381 agagccgctt ggacaaagtt gaggttgaga ttgtagaaga tagtcgttcc ttcacgttca
    10441 aacttgtcgc tagcttctac agaaactact acatacaagt ccccataagg tccaccgtta
    10501 aagcctgctt cgccttgacc agcgaggcga atttgttgac ctgtttccac accagcaggg
    10561 attttcacat gtacgctatg agcttgtttc tcatgacctg ttccatgaca ggttgtacat
    10621 ggatatttga tttcttttcc tcgaccgtga cagacatcac aggttacttg gcgacgcatc
    10681 ataccaagag gagtctgcgt atcgacgtta atgacaccag cgccatgaca gcgtccacaa
    10741 gtgactggac ttgtccctgg cttagcacca gagccattac atgtacgaca gccagcttca
    10801 cgatgatact taacttcctt ctcagttccg aagatagctt cttcaaaggt caaattgaca
    10861 cgatactgga gatcatctcc ttggcgagga gcgtttggat tgcgcgaaga accgcctccg
    10921 ccgaagaaac ttgagaaaat atcctcaaaa ccaccgaagc cacctgcccc attgaaacca
    10981 ccgaaaccac cagctccacc aaaaccacca ttggcgcctg cagcaccata ctggtcatag
    11041 gcagcacgtt tttggtcgtc actcaaagtc tcataggctt cttgaacttc cttgtacttg
    11101 tcctcagcac caggctcctt gttgatatct gggtgatatt ttttggaaag cttacgataa
    11161 gcctttttga tttcgtctgc cgaagcgttt ttggataccc ccagacgatc ataaaattca
    11221 gtattgttca tacaagatac caagaccgta aaattcgact gaaaaatagg aaatctgacg
    11281 ctggagcgac gctcctagac agatttctct tttttccgag aatttaggtc gggttcaatt
    11341 cctttctttt atattgatga gataatactc cagccactcg gccctatccc tttttatcga
    11401 aaaacagagg ctgggttgca acctctgcaa ataagtaaat taactttatt ttgattttaa
    11461 atatcctata agtacagaaa tatttatata tttttgtctc ttcttagtat ttgctatata
    11521 attccaattg atcataagaa atacaactac tgtccaaatc ataccaatta tgaacggtat
    11581 tacaaattta tatgtttgta tttctaatga tatcatagct gataccagcg ccgatacaaa
    11641 tgcagacaac aatactgagg taacaaaatt ccttaccgct tcatcatttt tgatacaact
    11701 atcatgttca gctaatataa tttctctata tctagctaaa tattctattg gaatattatc
    11761 aataaaatct tttgatgttc tatagttatc agcttgatta caaaaatcat tataaacttt
    11821 tcgtgtattt tttagatact cttcatccaa tacactcgtc ttacttttcc gtaaactctc
    11881 cgtctacgac gtcatcgcct gcgtttcctg ttgcttgtgc gccttctgct ccttcttgag
    11941 cttgttgcgc tgctgcggct tgttcgtaga gtttaacagc aagtccttga gctttttcgt
    12001 tcaatgcttc aagtttcgct ttcatgtcgt ccaagttgtt gtcttcttga gctttcttaa
    12061 ggtcatcaag ggcagcttgg gcagcgtcac gttctgcgtc gaagccttta ccttcagttt
    12121 ccttgattgt cttttcagtc gcaaagattg cttggtctac ttcattacga aggtctactt
    12181 cttctttacg tttcttatca gcttcagcgt ttgcttctgc atctttcatc atgcggtcga
    12241 tttcttcgtc agtcaaacct gagttcgatt ggatgacaat agtttgttct ttttgagttc
    12301 caaggtcttt ggccttaaca gacacgatac cgttcttgtc gatgtcaaat gttacttcga
    12361 tttgaggaat tccacgaggt gcagctggga tatcagtcaa ttggaagcgt ccaagagtct
    12421 tgttatctgc tgccattggg cgttcacctt gaagaacgtg gatatcaacg gctggttggt
    12481 tgtctgctgc tgttgagaag acttgtgatt tagatgttgg gattgtagtg ttgcgatcga
    12541 taagttttgt aaatactcca cccattgttt cgataccaag tgacaatggc gttacatcaa
    12601 gaaggacaac gtccttgaca tcaccagtaa tcacaccacc ttggatagcc gcacccatag
    12661 caactacttc atcagggttt actgatttgt ttggttcttt accagtttca gctttaacag
    12721 cttcaacaac ggcagggata cgagttgaac caccaacaag gataacttcg tcgatttctg
    12781 acaagctcaa acctgcatct gaaagggctt gacgaactgg aacttttgta cgttcaacaa
    12841 ggtcacgagt caaatcgtca aatttcgcac gagtcaaagt catttccaag tgaagaggtc
    12901 cagcctcacc tgcagtgata aatggcaagc tgatttgtgt tgaagttaca ccagaaaggt
    12961 ctttcttcgc tttttcagcc gcatctttca aacgttgcat tgccatcttg tcagtagaca
    13021 agtcgatacc gttttctttc ttgaattctg ctaccaagtg gtcaatgatt ttttggtcaa
    13081 agtcgtcacc accaagtttg ttgtcccctg cagttgacaa tacgtcgaag acaccgtcac
    13141 ccaattcaag gatagagacg tcgaatgtac caccaccaag gtcaaatacc aagatttttt
    13201 cttctttgtc agtcttgtcc aaaccataag caagagctgc tgcagttggt tcgttaacaa
    13261 tacgttctac ttcaagacca gcaattttac cagcgtcttt tgttgcttga cgttgagcgt
    13321 cgttgaagta agccggaact gtgataacag ctttggttac tttctcacca aggtagtctt
    13381 cagcgtagcc tttcaagtat tgaaggatca tagctgagat ttcttgtgga gtgtattctt
    13441 ttccatttgc agaaactttt tcagaagttc ccatcttaga tttgatagag ataactgtat
    13501 ctgggtttgt gactgcttga cgttttgcag catcgccaac gataatttct ccgtttttga
    13561 atgagactac agatggagtt gtgcggtttc cttctgggtt tgcgatgatt ttgctttcag
    13621 ttccttcaag aactgcaact gctgagtttg ttgtacctaa gtcaataccg ataattttag
    13681 acatgtgttt ttctccttgt tagttaattt tctatttttc tttttgatac tcttcttaag
    13741 tggcgacgcc gtcagagctt gacttcgtca atctctttga ctaaactttg agcctaaggt
    13801 ctcaaaattt gcgcaaatag cgccacggcg aagagtatcg tctttggttc gcttcgctca
    13861 ctattacaaa gccaaacata ttttatcttt cttcatagtt tattgtcgtt tcggacaagt
    13921 tttctattat gtaaattgcg acacgaggag tcgaaatcga ttttatttcg acgacgagtt
    13981 agtaaggaag ctagacaaac gccatagcga ttgccatttt ctgacgagtt gctttagcta
    14041 ccgtcagaat tgccgaatcg aacacgccct aagctctgag taaaaaagat agattttctt
    14101 gtgttcatcg aacacttcgt caatctccta tttttactgc gagcttttta cgggctttgt
    14161 atcttaatta tacaccacta ccattgctgg gcgtaggatg cggtcatgga gtttgtagcc
    14221 tttttgaaag acttgggcga tggtatctac tgggtgttca tcgtctgctg ggagagtttg
    14281 gatggccata tggtagttat ggtcaaattc gccatctgct gcgatttctt caattccttc
    14341 ttctttcaaa gcgtgaatca agctttcttg caccatcccc aagcccttct tcacatcatc
    14401 tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca agagatggta agattgcttt
    14461 tgccaagtcc tggctacgat aacgttgcaa gttttgacgt tcttcattgg cacggcgttg
    14521 gatattttgc atttctgcat gagcgcgaag atatttgttt tcgaactcat ctgcacgttc
    14581 atttgccaag tccaactcag acttttcagg agttgtttct tcagctgttt ccacaacttc
    14641 ctcttcttga acttcttcta cttcttcatt ttttatatct tgggccatgt tcgcctcctt
    14701 taatgatttc aatcttaatg tacttcgtaa tgattactgc tgaggtagcg gtaaaaatct
    14761 gtcaacttca tggtcaaaac acggttgacc acattgactt gattgattag ctgttggtaa
    14821 tccagattaa ctggaccgat aatggctaga attccaactc cccgataagg aatgaggaac
    14881 ttactactaa tcaccgctag gtcagctaaa caggactctt gaccgtctgc aacacgaaca
    14941 ttttgcatct gatcctcacg caacccctca cgaatctcca aggccacctt ttgcggttgg
    15001 tcaaagaact gataggcttc tagattggca aaattcaaga gattgacctt gcccgccatc
    15061 acaatgtttt cgttgaacat ttccttaaag atgtgttcaa agagatcgat gacattatcc
    15121 gttgttgtaa agtaacgctg gataatctgc ggaatctccg tccgaatctt gtagtgaata
    15181 tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc tcttcagttt cagcaaatcc
    15241 tcctgcaaga agttccttgg aatcagaaac tgactagtaa ccgttcgcga ctcgtctagg
    15301 gtaaataccg ccaaggctgt atgttgcccc aaaacaacga tatcaaaggc tgtcaaacgt
    15361 tgcctgctcg gctcaacatc cagtgccact accgtacagc cactcaggtc tgttagcaag
    15421 ttagcagcct cttgcagaat atcctccaat ttgaagaatt cctgatcaaa ggctttgaca
    15481 atctcatata cctcattttc agccagtcgg tcaaaatcca gtgagtgttt cacatagtac
    15541 tgaaaaccag caacacttgg catccgaccg cttgaagtat gagccttctc aagcaaccct
    15601 tgtttttcta gttccgccat gtcattacga atggttgcac tgctagagtt aatagactct
    15661 tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa agatgtcaat aatcagattt
    15721 aaaatatcct gctgacgctc tgtaaccatc tcatcactcc tctctgtctg atcaattagc
    15781 actcaatgca tccaagtgct aacttatgat tctattatac acccttagaa gagaatgtca
    15841 agacaaaaac tcaaaaaatt agcactcttt tatcaagagt gctaaaaatc aatctgaaga
    15901 cctagaacct tgctattcat ctactcggta tttccttttt agtctgaaat aaccatgaat
    15961 tagataagaa atcagaaaag catataaaac aaaaataaga aagaaagaca tagaaagatc
    16021 ctctctaaac aaactcgtac aaacaacaag accacctaag aaagtagctg tacaggaacg
    16081 acgtctagat cgcataactt cccatttgag ccccttactc atatagactt gatcctctgg
    16141 aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctgctccta tcaattccca
    16201 acctctatct ctaaaatctt gcagttcatg cttatatttt ttaagaaatc tagaatcata
    16261 gatacggtag atgacatcgt ctggttgaca ttggtcaaaa tagaacaaac caaaacgact
    16321 agttctatac ctccaacctt tcaaatgcat ctcatgtaaa tattcttctt ccttgtccaa
    16381 atcaacaata gtgaaaatcc gaaattctac tctgctattc attgtcttac cccaaaatta
    16441 gaaaacatgc ctggcgttat ttattagata attctttcca cttttgactc aatctccaaa
    16501 aaatataaga aatctgaatc gcaaaaacta tcaataaaac ccaatctatt atgaaagtca
    16561 aaaacacttc ccaactgaaa gaactacctc cagtgacaaa ctttgagaaa aacggtagta
    16621 gagctaaaaa gagaagcaaa ataggaagca tccgcattgt taaaatcctt ttggcataaa
    16681 aaaatcttta tttaaacgaa aatattatgg caaaatttac gccagttttt gaacggctga
    16741 tgtagatatt ttatactttc aaaatgttta aatgtgatta tttatttttg aaaaatagct
    16801 caccagcccg actgaaagtg cttataaatg ataataagtc gcctgccgaa aacagcgaaa
    16861 aatagcggtg ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt
    16921 tcaacaattt agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga
    16981 tagtttattt tatggagaag tagattttta gaatgcggag gattcaatat ggttgagttt
    17041 ataaagtcta agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct
    17101 attgtatcca aaggatggaa aaatggtgag catatcgctt acgaagaata cttcactgat
    17161 ggtcgaattg aagttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat
    17221 tcactgtatt accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac
    17281 agcgttcgag caggattaca acaagctatt gaatatggag agattttaga tgttccattt
    17341 gtttattctt cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt
    17401 gagctggagt tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa
    17461 aaaggattga tgtacgaaat tacagaagct atctcaactc catactatac agacgccttc
    17521 tcaatgaaaa cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt
    17581 gccagaggac aaaaacgagt aatgtttgtg atggcaacag gaacggggaa aacgttcatg
    17641 gcttttcaaa ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta
    17701 gcagatagaa acatcttagt agaccaaacg atggctgaag actttaggcc attcgaaaag
    17761 gtaatgacga aaattacacc aaaacttttg actgctcctg aaaaattaaa ttcttttgaa
    17821 atttatctag ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa
    17881 aaatttgaca aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct
    17941 aaggaagaca gtaactggcg taaggtgatt gattatttca gttctgcgac acagattggg
    18001 atgaccgcta ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtgagcca
    18061 atctatactt atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt
    18121 atgagggtta atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat
    18181 actaacggac aattaataga agataggtac tacggcagga aagattttga taaaaccatt
    18241 gtcattgatg atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaagc
    18301 aatgcacgat ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg
    18361 cgtgctgcac ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg
    18421 caagtaactg gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat
    18481 tctaattttc ccgctattgt aacaacgtct aaattattaa cgacaggagt taatgctaaa
    18541 acatgtcgtt tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt
    18601 attggtcgtg gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat
    18661 tttcgaaatg ttaccaattt gtttgctgac cctgattttg atggtgagcc agtgaaggtg
    18721 ctggaaacag gtgcgaaaac agtcagtggt tctacgcccg gtttcgtaga tgaggaaggt
    18781 gacccagtaa aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt
    18841 caagtattgg atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcggaag
    18901 aatatcttag gtagctacgc cactttgaac gattttatca cagtttggca tacggcggat
    18961 aaaaagaagc ttatcttaga cgaactttat aaaaaaggag tttatctaga tgctattcga
    19021 gagtcggagg gaatatcaga acaagaaatc gatgattttg atttactcct aaaacttgcc
    19081 tatggtcaaa aagaattaac caaaacggaa cgtatcaata aactcaaaca aagcggatat
    19141 ttatataaat atagtgagga agcgcgtgct gttttggaaa ttttactgaa caaatacatg
    19201 gataaaggta ttggagaact cgaaagcatt gaaacattaa aacttccaga atttcagata
    19261 tatggtggaa ccttcaaaat catcaatact tattttggag ataaaaaacg atatttacaa
    19321 gcaattaaag aattggagca agagctattt acagtagctt aatgaaagga aagtatgtca
    19381 attacatcat ttgtaaaaag aattcaagat atcactcgaa acgatgctgg tgttaatggt
    19441 gatgctcaac gtattgagca aatgtcttgg ttattattct taaaaattta tgatagccgt
    19501 gaaatggttt gggaattaga agaagacgag tatgagtcaa ttatcccaga ggaattaaaa
    19561 tggcgaaatt gggctcatgc tcaaaatggg gaaggggtat tgacaggcga tgaattactt
    19621 gattttgtca ataacaagtt attcaaagag ttgaaagagc ttgaaataac ttcaaatatg
    19681 cctattcgaa aaacgattgt taaatcagct tttgaagatg cgaacaacta tatgaaaaat
    19741 ggcgtcttgt tacgccaagt catcaatgtt attgatgaag ttgatttcaa tagccctgaa
    19801 gatcgtcatt cgtttaatga tatttacgaa aaaattctta aagatattca aaatgctggg
    19861 aactcaggag aattttatac gccacgtgca gcgactgatt ttattgccga agttcttaac
    19921 ccaaaacttg gagaatcaat ggcagacctt gcttgcggaa caggaggctt cttgacttcg
    19981 actctgaacc gtttaagtag tcaacgtaaa actagtgaag ataccaaaaa atataataca
    20041 gctgtttttg gtattgaaaa gaaagcattt cctcatcttt tagcagttac aaatctgttt
    20101 cttcacgaaa ttgatgaccc taaaattgtt catggaaata ctttggagaa aaatgttcgt
    20161 gaatatacgg atgatgaaaa atttgacatt attatgatga atccaccttt tggagggtca
    20221 gaattagaaa caataaaaaa taactttcca gcagaattac ggagttctga aacagctgat
    20281 ttatttatgg ctgtcattat gtatcgtttg aaagaaaatg gtcgtgttgg agttatttta
    20341 cctgatggtt ttctatttgg tgaaggtgta aaaactcgct tgaaacaaaa actggtagat
    20401 gagttcaact tgcatacgat tattaggttg cctcatagtg tctttgcacc gtatacagga
    20461 atccatacga acattctttt ctttgataaa acaaagaaaa cagaagaaac ttggttttat
    20521 cgtttagata tgccagatgg ttataaaaat ttctcgaaaa ctaagccgat gaagtcagaa
    20581 cacttcaatc ctgttcgtga ctggtgggaa aatcgtgaag agattctgga aggtaagttc
    20641 tacaaatcta aatcatttac acctagtgaa ttggctgagt tgaattataa tttagaccag
    20701 tgtggctttc caaaagagga agaggaaatc ttaaatccct ttgagttgat tcagaattat
    20761 caagcggaaa gagcaacttt aaatcataag attgataatg tattagctga tattttgcag
    20821 ttgttggagg acaaataatg acaccagaac aacttaaagc aagtattctc caaagagcga
    20881 tggaagggaa attagtgccg caaaatccca atgacgaacc tgcaagtgaa ttattaaaga
    20941 gaattaaagc tgaaaaagaa aaacttatca gtgaaggaaa aatcaaacga gataaaaagg
    21001 aaactgagat atttcgtggt gatgatggga aacattatgg gaagtttgct gatggaagta
    21061 ctcaagaaat tgatgttcct tatgatattc ctgatacttg ggagtgggtg aggttttcta
    21121 cattggttga aattgtcaga ggtggctctc cacgaccaat caaagattat cttacttctg
    21181 aagtagatgg aataaattgg ataaaaatag gtgatactga aaagggtgaa aagtatataa
    21241 ataatgttaa agaaaaaatc aaaaaatcag gacttaacaa aactagattt gtaaaaaaag
    21301 gtacattttt gttaactaat tctatgagtt ttggtagacc ttatattttg aatgttgatg
    21361 gtgcaataca cgatggatgg ttggctattt cgaactatga aaactcatta aataaagatt
    21421 acctattcta tattctttca tcaaatgtag tttattctca atttctatct ctaattagtg
    21481 gagctgttgt gaaaaacttg aatagtgata aagttgcttc tattcttatc cctctccccc
    21541 cactatccga acaacaacgc ataatagaag caatcgaatc agctttagaa aaagtagatg
    21601 aatatgctga aagttataat agactagaac agctagataa agaatttcca gataaactaa
    21661 aaaaatctat tcttcaatat gctatgcaag gaaaattagt tgaacaagac ccaaatgatg
    21721 aatcagtcga agttttactt gaaaaaatac gagcagaaaa acaaaaactc tttgaagaag
    21781 gcaagattaa aaagaaagat ttggacattt ctattgtttc ccaaggagat gataactctt
    21841 attatgagga agtaccttgt gaaataccag aaagttggga atgggtgagg ttaaacgata
    21901 taacctccta cattcaaaga gggaagtctc caaaatattc aaatattcct atataccctg
    21961 tgattgctca gaaatgtaat caatggtctg gcttttctat tgacttagca agatttattg
    22021 atcccgaaac agttcatagt taccagaaag aaagattact aagagatggt gatttaatgt
    22081 ggaattcaac aggtctaggt acgttaggac gattagctat ttaccatgaa aataaaaatc
    22141 cttatggctg ggctgttgca gatagccatg ttacagttat aagagtctta tcgggggtta
    22201 ttaattgcca tttcatctat aatttccttt cctctcctat tgttcagtca gttattgaag
    22261 aaaaagcgtc gggtagtaca aaacaaaaag aattattaac gaaaactata aaagaatatt
    22321 taatccccct cccacccctt cctgaacaat ccagaatcgt tgataaaatc gaacaatttt
    22381 tcgcccatat tgacgcacta atttagtata atagttttac gtgcggtgga atttctatca
    22441 aacataagat aggagtttta cgttgaaaga ttttgaatta catttgaaga aagctggttt
    22501 agctgaaaat actgtgcgtt cgtaccttta tggtgttcga tttttcttgg agaattacga
    22561 actcaaaatg gaagatttat ttgaatacaa aggatattta ttagacaatt ttaaacctaa
    22621 aactgtcaat ttgcgactac aaggagtaaa taaatatctg gcttttattg gtcatgatga
    22681 tttgaaatta aaatttgtca aagtacagca aaaaccattt ttagaagatg tcattagcca
    22741 tgctgattac ctttttctta aacgtagttt gaaaaaagat ggtattttaa aatggcattt
    22801 tgtcgtttgg tttttaggtg caactggggc tcgtgtaagt gaacttatta aactaaaagt
    22861 agagcatgta gaaatcggtt attttgacat ttactcaaaa ggtggtaaaa ttcgtagact
    22921 gtacattcct aaaaaattaa gaaatagttg tcttagttgg ttagaatcag aaaatcgccg
    22981 aagtggttat ttatttttga ataaatttaa cgaaccaatt acagcaagag gagttgctca
    23041 acagttaaaa aattatgctg ataaatacaa aatgaatcct aaagtaattt accctcattc
    23101 ttttaggcat ttatttgcta agaatttttt agcgaagtat aatgatattg ccttgcttgc
    23161 agatttgatg ggacacgaaa gtatagaaac tactcgaatt tatctaagga aaacagctac
    23221 tgaacaacaa aatattgtag ataaaattgt taattggtaa aaaataacag gtggtcaaac
    23281 tgactacctg ctatttttgt gattatggct cttatt
//
LOCUS       DAVHSH010000026        22997 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000026 DAVHSH010000000
VERSION     DAVHSH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22997
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.026"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(50..3226)
                     /gene="carB"
                     /locus_tag="VVR08_001201"
     CDS             complement(50..3226)
                     /gene="carB"
                     /locus_tag="VVR08_001201"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU6075121.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKIAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3539..4618)
                     /gene="carA"
                     /locus_tag="VVR08_001202"
     CDS             complement(3539..4618)
                     /gene="carA"
                     /locus_tag="VVR08_001202"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU6075122.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4668..5591)
                     /locus_tag="VVR08_001203"
     CDS             complement(4668..5591)
                     /locus_tag="VVR08_001203"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU6075123.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEDLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5610..6131)
                     /gene="pyrR"
                     /locus_tag="VVR08_001204"
     CDS             complement(5610..6131)
                     /gene="pyrR"
                     /locus_tag="VVR08_001204"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU6075124.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6342..6971)
                     /gene="nth"
                     /locus_tag="VVR08_001205"
     CDS             complement(6342..6971)
                     /gene="nth"
                     /locus_tag="VVR08_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU6075125.1"
                     /translation="MVLSKKRARKVLEEIISLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(6971..7513)
                     /locus_tag="VVR08_001206"
     CDS             complement(6971..7513)
                     /locus_tag="VVR08_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU6075126.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7683..7999
                     /locus_tag="VVR08_001207"
                     /pseudo
     CDS             7683..7999
                     /locus_tag="VVR08_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            8238..9797
                     /locus_tag="VVR08_001208"
     CDS             8238..9797
                     /locus_tag="VVR08_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6075127.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9946..10845)
                     /gene="htpX"
                     /locus_tag="VVR08_001209"
     CDS             complement(9946..10845)
                     /gene="htpX"
                     /locus_tag="VVR08_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU6075128.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(10847..11407)
                     /locus_tag="VVR08_001210"
     CDS             complement(10847..11407)
                     /locus_tag="VVR08_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU6075129.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11501..12214
                     /gene="rsmG"
                     /locus_tag="VVR08_001211"
     CDS             11501..12214
                     /gene="rsmG"
                     /locus_tag="VVR08_001211"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU6075130.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12468..13751
                     /locus_tag="VVR08_001212"
     CDS             12468..13751
                     /locus_tag="VVR08_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU6075131.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13946..15517)
                     /gene="ffh"
                     /locus_tag="VVR08_001213"
     CDS             complement(13946..15517)
                     /gene="ffh"
                     /locus_tag="VVR08_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU6075132.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15529..15861)
                     /locus_tag="VVR08_001214"
     CDS             complement(15529..15861)
                     /locus_tag="VVR08_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU6075133.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(15952..16329)
                     /locus_tag="VVR08_001215"
     CDS             complement(15952..16329)
                     /locus_tag="VVR08_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU6075134.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKRDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYILTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16401..17705
                     /locus_tag="VVR08_001216"
     CDS             16401..17705
                     /locus_tag="VVR08_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU6075135.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            17718..18524
                     /gene="yidA"
                     /locus_tag="VVR08_001217"
     CDS             17718..18524
                     /gene="yidA"
                     /locus_tag="VVR08_001217"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU6075136.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(18580..18651)
                     /locus_tag="VVR08_001218"
     tRNA            complement(18580..18651)
                     /locus_tag="VVR08_001218"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18616..18618),aa:Arg,seq:cct)
     gene            complement(18694..19041)
                     /gene="rplS"
                     /locus_tag="VVR08_001219"
     CDS             complement(18694..19041)
                     /gene="rplS"
                     /locus_tag="VVR08_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU6075137.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19160..19489)
                     /gene="crcB"
                     /locus_tag="VVR08_001220"
     CDS             complement(19160..19489)
                     /gene="crcB"
                     /locus_tag="VVR08_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6075138.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(19483..19857)
                     /gene="crcB"
                     /locus_tag="VVR08_001221"
     CDS             complement(19483..19857)
                     /gene="crcB"
                     /locus_tag="VVR08_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6075139.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19854..20120)
                     /locus_tag="VVR08_001222"
     CDS             complement(19854..20120)
                     /locus_tag="VVR08_001222"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU6075140.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20236..20679)
                     /locus_tag="VVR08_001223"
     CDS             complement(20236..20679)
                     /locus_tag="VVR08_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU6075141.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            20783..21718
                     /locus_tag="VVR08_001224"
     CDS             20783..21718
                     /locus_tag="VVR08_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU6075142.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21772..22056
                     /locus_tag="VVR08_001225"
     CDS             21772..22056
                     /locus_tag="VVR08_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU6075143.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(22113..22331)
                     /locus_tag="VVR08_001226"
     CDS             complement(22113..22331)
                     /locus_tag="VVR08_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075144.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(22328..22902)
                     /locus_tag="VVR08_001227"
                     /pseudo
     CDS             complement(22328..22902)
                     /locus_tag="VVR08_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6764 a         5150 c         4398 g         6685 t
ORIGIN      
        1 tccctgtgta ctgttctaaa ttcagtctgc tatatcttat tttttctatt taaatcgctt
       61 ctgtaacaaa gctacgactt tcaagtacct taagcatggc attagctgta tctagcgctg
      121 tgaagagggg caccccgtgt tcaatggctg aacgacgaat ttgctcacca tcttcgtcag
      181 cagttcgttt tgttcctact gtgttaatga tagcttgaat tcttcctttg cgtacaaaac
      241 ttgggatatc cttatcgtca tcaccaatct taccaacagg ttgggcttgc aagccatgac
      301 tagcaaagaa ggctgctgtc ccctctgtcg caaggattcc ataaccaatg ttttggaaac
      361 gacgagccaa gttcaaggct tcttctttgg catcatcagc gatggtaaag acgacattac
      421 caaaagttgg caagtgtaga taagaagctt caaaggcttt atagagagct ttttccaaag
      481 tagcatcaga acccataact tcacctgttg acttcatttc aggaccgagc aagctgtcta
      541 ccttagctag tttggtaaag gagaagacag gtgccttgat atgaacacgg gtgctttcag
      601 ggtaaagtcc attttggtag ccaagttctg ataaactttg accaagaatg agcttggtcg
      661 ctacttgagc cataggaata ttggttacct tagataggaa tggaacggta cggctggcac
      721 gtggattgac ctcaataacg tagacttttt catccttgat aacaaactgg atgttcatca
      781 ttccaaggca gtgaagaccg attgctaagc gtttggtgta gtctgcgatg gtctcctgaa
      841 ccttttgcga caaggtttgt ggtgggtaaa cagccattga gtcacctgag tggacaccag
      901 cacgttcgat atgctccata ataccaggaa tgagtacatt tttaccatct gaaatggcat
      961 caacttcgca ctcttgccca acgatgtaag agtcgacaag aactgggtgg tctggactag
     1021 ccttaacagc agttcgcatg taagaacgaa ggtcttcttc gttttcaacg atttccatgg
     1081 cacgtccacc aagtacataa gatgggcgga caagaactgg gaagccaatc ttacgagctg
     1141 caagagctgc ttcttcttca ttggtagccg tttgtcctgg tggctgtgga atatccaatt
     1201 ctttgagagc ttgctcgaag aggtcacggt cttcggcacg gtctaggtca gcaacctgtg
     1261 taccaaggat ggtcacacct gcttttgcca atggctccgc aaggttgatg gctgtttgac
     1321 caccgaactg aacgataact ccctttggtt gttccaagtc aatgacgttc ataacatctt
     1381 cgaatgtcaa tggctcaaag taaagcttat ctgatacaga gaagtctgtt gaaacggtct
     1441 ctgggtttga gttcatgata atagcttcat aaccagctgc ctggatagcc ttaacagagt
     1501 gaacggttgc gtagtcaaac tcaacccctt gaccgatacg gattggacct gaacctagaa
     1561 caagtacaga ttctttatca gatctgatag attcattttc ccaaccatag gttgaataga
     1621 aatatggcgt ttcagagtcg aactctgccg cacaagtatc taccatctta tagactggga
     1681 caatcttgtt ttccaaacga agttggcgaa cttgatcatc agtcgttccc cagagttcag
     1741 caatcttacg gtctgagaaa ccattaagtt tggctatttt caaaacttct agatcttgtg
     1801 gatgagcacc caattcttgc tcaatttcaa agatatgcaa gagtttatca agatagaaga
     1861 tatcaatttt tgtaagctct gcaatttctt caggtgtgta gccacgacga attgcttctg
     1921 atacgtagaa gagacggtca tcttgggctt tgacaacctt ttcaatcaag gtatcatcag
     1981 aaactgctgc aagttcaggt atttcattgt ggtgcacccc aatttcaagg gatcggcagg
     2041 ccttgagaag agattcctcg atgttacgac cgattgccat gacttctcca gtcgccttca
     2101 tttgtgtacc gagacggcgt tcaccctttt caaacttgtc aaatgggaaa cgtggaatct
     2161 tagcaactac gtagtcaagg gctggttcaa acatggcata ggttgaacct gtaactgggt
     2221 ttataacctc atccaaggtc aaacctactg caatcttggc agccaactta gcaatcggat
     2281 atcctgtcgc tttagaagca agggctgacg aacgtgatac acgagggttt acttcgataa
     2341 cataatactt gaaactgtta ggatcaagag ctagctgaac attacatcca ccttcaatct
     2401 tgagggcacg aataatgctc aagctcgcat cacgaagcat ttggttttca tagtctgaca
     2461 tggtttgcgc aggggcaaat acaatggaat cccctgtgtg aatcccaact gggtcaaagt
     2521 tttccatgtt acaaacaacc aaggcattgt cagctgagtc acgcatcact tcgtattcaa
     2581 tttccttgaa accggcaatc gaacgttcaa tcaaacattg ggtaacaggt gacaatttca
     2641 aaccattttc agtgatttca cgcaattctt tctcgttggc acacatacca ccaccagtac
     2701 caccaagggt aaaggctgga cgaacgatga ctgggtagcc aattgtcgct gcaaaggcaa
     2761 ttgcttcttc tactgtgtta acaatttcag attctggaat gggttgctca agctcttcca
     2821 tcaattgttt aaagaggtca cggtcctccg cttggtcaat ggcagacaat ctagtaccga
     2881 gaagctctac accaagctca tctaagatgc catttttaga caattccatg gccatgttga
     2941 gacctgtctg accaccgagt gttggtagca aggcatctgg acgttcctta cgaagaatac
     3001 gtgtcacaaa ctcaagtgta atcggttcaa tgtaaacctt atcagcaatt tccttgtccg
     3061 tcatgatggt tgcaggattt gagttaacca aaacaacctc ataaccttcc tctttcaacg
     3121 acaagcaagc ctgggtccca gcgtagtcaa actcagcagc ctgaccaata ataatcggac
     3181 cagaaccaat caccataatt ttttgaatat cagtacgttt aggcatatat aagatattaa
     3241 gggcgtcaag cggacaaagc taaaatagga gttatgacga agaactgtca gttctaggaa
     3301 taactatctt tttagcaccg tccgtagccc gtattcagtt cagcaaatac ggagcaccct
     3361 tctcctttct attcgtcgcc tctcagggcg acattaaata agatacaaag gacgaataga
     3421 aagcgattga attttagaaa atcaaggaag gagtgacaat ccaagttggt ttctctacat
     3481 tctgagcttt ccgtccgtgt tcagttacat aaattctccg acgagctttt actcgttctt
     3541 agtttgattg tttaaaaact tccatcatct cgataaactc gtcaaatagg tagctagcgt
     3601 cgtgtggccc aggggctgca tctgggtggt attgaacaga gaaagcaggt tggtatctgt
     3661 ggcgcacacc ttccactgac ttgtcattga tttcttcgtg ggtaataatc aagtgctctg
     3721 gcaaatcctc gcggctgact gcataaccat ggttctggct ggtgaagtct actcgtcctg
     3781 ttgcgatttc acgtaccgca tggttgaatc cacggtgacc aaacttcatc ttataggtct
     3841 tagccccgtt tgccattgca aagagttggt gtcccataca aataccaaag attggaattt
     3901 ttccttgtac accgcgaatc atgtcgagtg cttgtggaac gtcttctggg ttacctggac
     3961 catttgacaa cataactccg tcaggattga gatggagaat ttcttcagcc gttgtcgaat
     4021 aaggaacaac tgtcacgtta cagttgcgtt tagaaagttc acgtaggatt gagtgcttga
     4081 gaccaaagtc cactagcacc acgctcaaac caactcctgg agctggataa gacgttttag
     4141 tagaaacctg tttgatattg tctgtcggta aaactgttgc ttggagctgg tccgtcacat
     4201 ggtccatact gtccccaaca tgggtcaagg ttgcacgcat agtaccatgc ttacggataa
     4261 tcttggtaag agcacgcgta tcaattcctg aaatccctgg aattttcttg gctttcaaaa
     4321 attcatccaa ggtcatttgg ttgcgccagt tgctagctct acgcgcttct tcaaaaacaa
     4381 cgactccctt acaagttgga ataatggatt cataatcatc acgattaata ccataatttc
     4441 ctaccaaagg ataagtaaag gtcaagattt gtccattata agactggtct gtaatggatt
     4501 cttggtagcc ggtcattcct gtattaaaga cgatttcgcc tgttacatca atatctgctc
     4561 cgaaggcctt gccttcaaaa actgtgccat cttctaatac tagaattctt tttgtcatat
     4621 tttcacctct cgtggacgct cactggcgtc ttttaacgtc ttgtgtttta gttggcgttt
     4681 ctactcgcta gtacggattc taagattgcc attcgaacaa agacaccatt ggtcatttgt
     4741 tggacaatcc gtgattttgg tgcttcaacc aagtggtctg ctatttctac atcacgattg
     4801 attggagctg ggtgcatgag gattgctgtt tctttcaaac gatcgtaacg ttcttgagtc
     4861 aagccatgtt gggcatggta gtcttctttt gaaaatacag ctccactatc atggcgttcg
     4921 tgttgcacac ggagaaacat catgacatca acctgatcaa tgatttcatc aatggttaca
     4981 aactttccat agtctgcaaa ctcttgactt ctccattcct caggtccagc gaaaaagagt
     5041 tcagctccca agcgtttcaa aatctgcata ttggatttgg caacgcgtga gtggtccaag
     5101 tcacctgcaa tagcaacttt aagatcctca aagtggccaa attcctcata aatggtcatc
     5161 aaatcaagca agctctggct agggtgttgg cccgaaccat ctccaccatt gatgatggaa
     5221 gtcgtaatcg ttggactagc aatcaattct ctatagtagt cgacctctgg atggcgaatc
     5281 acacagacat ccactcctaa agcagacaga gtcaaaatgg tgtcataaag tgtctcaccc
     5341 ttattaaccg aactagtctt cacatcaaag tcaagtcgtt ccaatccaag tttaatctct
     5401 gcgacttcaa aggacttatg tgtccgtgta gaatcctcaa agaagagatt ggaaacaatc
     5461 ggatggtctt catagggaag ctgggctcca tttttaaact caattcctcg cttgatcaat
     5521 ttcattactt gatcgacagt gaggtcttcc atggacacca catggttcaa tgcttgttga
     5581 ttttctgaca tggctactcc tttaactttc taagcttctt cagtaatcag aactctgtct
     5641 tggtcatcaa gttctgtcat ctctacgatg atttcttcag aacgactggt tgggatattt
     5701 tttccaacgt aatctggacg gattggcaat tctctatgtc cacgatcgac tagaactgct
     5761 aaactcacac gcgcaggacg accatgaccg acaatattat caatagcagc acggatggta
     5821 cgacctgtat agagcacatc atccaccaag ataacttcgc ggtctgtcac atcgacagaa
     5881 accaaagaag tatcttctcc acttttaaca tcatcacgga aaggtttagt atccaattcc
     5941 acaacaggaa ctgaaagatt ttctaactgc ttcaaacgtt cttggattcg gtgggcaata
     6001 aagacaccac gagttttaat accagccaag acgatcttat tcaaatcttt gttgcgttcg
     6061 ataatctcat aagtaatacg cgtaatcgct cgtttgacgg tcaattcgtc tacaacttct
     6121 tttgttttca tgacaaacct ccaaaaagaa aagtctcctt aaacaaggag acttgaaatt
     6181 tatagccaag cgagccctac tgcacacagt atagacttca cccttctact ttatcgcgct
     6241 ccttgcctgc ctcacgggac aggtttaaag gaatatttag ttatcattta ctatagcaca
     6301 aagcatgctt aaaatcaagc aaaaagtttc aatgtagtat cttacaaatt gctaaaatca
     6361 tataattgtg ggtactggtc acactctgga ttttttggat ggcaaatggc tcttccaaaa
     6421 taaatcatgg cctgatgggc agctaaccac tgctcaggcg gcaagatatc catgacccgc
     6481 ttttccacct caagtggcgt cgctgatttt ttgacaatat cgtggtgttt gcaaatacgc
     6541 tccacatgag tatccactgc aaaggctgga atcccaaatc ctacactcat gacaacattg
     6601 gctgtcttgc gaccaacacc tgccaaactc tccaattctt cacgtgtctg agggacttga
     6661 ccatcaaaat cgtctagtaa ctgttgggca cattttttaa ggaatttagc tttattccga
     6721 tacaatccca agcgagaaat atgtgaagca atctcactct ctgtcgctac agacatagct
     6781 tggggtgttg gaaaggcaac aaagagacct ggtgtggcct tatttaccgc tgcatctgtc
     6841 gtctgggctg ataacatgac cgcaaccagg agttcaaaat gattggtaaa atcaagacta
     6901 ggcttggcat ctgggaagag ggaaatgatt tcttctagca cctttcgtgc tcgttttttt
     6961 gacaagacca ttattcatct ccgtcaaata gtccttgtaa gccagcaaaa ggactgtttt
     7021 cttctttctt tactgcttgt tgagcttggt attcttcctc tgtcatgatt tgccagtcat
     7081 ttcctgagac aaatccttga ccagcttctt cttcagccgt caagaccttg ataggaatgt
     7141 ttagcaggat attgtctgat acactctcag caaggtcaag ctccccattt tcgatgggca
     7201 agaccaagtc atcatctaaa acttcttgat ctagctggtt agttgcgcct tccatgaaaa
     7261 cttccgtgac tggataagat tcaactaact caactggctc catactgcga ctcgaagcaa
     7321 gaacaatggt ataagatagt tgataatcta agaaatacat acggtcttca tattgtactt
     7381 tcccaactgc aaggatatct tttacatcta aaatttcttg attacgtgca cgcaggtcat
     7441 caactaaatc taacgtttgt tcaaagttca aaccttcaga ctgcttacga atttcttgaa
     7501 tatttaattt catacttcct ccataaagat ttactctctt gattatacca tgaaaaggct
     7561 acaaatcagc acaccaaact ttgtaattaa aattcgaaat tttaacatat tcactatgac
     7621 agttttattt tttagtgcta tactataggg aaagagtaca tcagatcaag gaggatgctc
     7681 acatggaaga caagaaactc attcaactcc tatccaagtt aaataaaagc taccaaaact
     7741 gtaaacaggg tacggcagat gatattcgac tacaagagct gctaaacact actatgcaag
     7801 agctcaaaaa acggaaaagt tgaacaacag tatcttaatt gatcttgaga aattttacca
     7861 acccaccagt cttctgattg gactgggtag cctaaaacta aacgatcaag cacgcactgc
     7921 ttggcgaaac tatgataaat tccattacga gcatgtcaaa cacgtactaa gtctctatgg
     7981 acctgttttt ggattttaga gcatagaatt tccagttttc tgttgacaaa atttccttaa
     8041 aggtataata taaagatact aatactcgga ggtaagggag acatgaacaa ctaagtctat
     8101 caaataaaga acctttattt agtagatctt gtttttgtct ctttttgtgt gctcttttat
     8161 gctctttttc tggcatgtta atagagtttt tttgacatag actttgggct ctactaggta
     8221 aagtagagct ttttgttatg cactatgaac attctagaaa gggaaatcat atgataaaaa
     8281 tcaatcatct aaccatcaca caaaacaaag atttacgaga tcttgtatct gacctaagca
     8341 tgaccatcca agacggggaa aaggttgcta ttattggtga agaaggaaat ggcaaatcaa
     8401 ccttacttaa aattttaatg ggggaagctt tgtctgattt cactatcaag ggaaacatcc
     8461 aatctgacta tcagtcactg gcctacattc ctcaaaaact tcccgaggag ctgaaaaaga
     8521 aaactttaca cgactacttc tttttagatt ctattgattt agactacagt atcctctatc
     8581 gtttggcgga ggaattgcat tttgatagca atcgtttcgc aagtgaccaa aagattggca
     8641 atctatcagg gggcgaagct ttgaaaattc agcttatcca tgagttagcc aaaccctttg
     8701 agattctatt tttagatgaa ccttcaaatg acctagacct tgagacagtt gattggctaa
     8761 aaggccagat tcaaaagacc aggcaaaccg ttattttcat ttcccatgat gaagactttc
     8821 tttctgaaac ggcagacact attgttcact tgcgactggt caaacaccgt aaagaagcgg
     8881 aaacgctagt agagcattta gactatgata gctatagtga gcagagaaag gctaattttg
     8941 ccaaacaaag tcagcaagct gctaacaacc aaagagccta cgataaaacc atggaaaaac
     9001 atcggagagt caagcaaagt gtagaaactg cgcttcgagc taccaaagat agtactgccg
     9061 gtcgcctatt ggctaaaaag atgaaaactg tcctctcaca agaaaaacgc tacgaaaagg
     9121 cagctcagtc catgactcaa aagccacttg aagaggaaca aatccaactt ttcttttcag
     9181 acatccaacc attaccagct tctaaagtct tagtccaact ggaaaaagaa aatttgtcca
     9241 ttgacgaccg agttttggtt caaaaactac aactaactgt ccgtggccaa gaaaaaatcg
     9301 gtattatcgg gccaaatggt gttgggaaat caactctgtt agccaagtta cagagacttc
     9361 tgaatgataa aagagagatt tcacttggtt ttatgccaca agattaccac aaaaaactgc
     9421 aattggattt atccccaata gcctatctca gtaaaactgg ggaaaaagag gaactacaga
     9481 aaatccaatc tcacctagct agtctcaatt tcagttatcc agaaatgcag catcaaattc
     9541 gctccttatc tggcggacaa cagggaaaac tcctgctttt ggatttagtc ctgcgcaaac
     9601 caaactttct cctgctggat gaacccacac gaaacttttc tcccacttct caaccccaaa
     9661 tcagaaaact ctttgccact tatcctggcg gtctcatcac tgtttcgcat gaccgtcgtt
     9721 tcttaaaaga agtctgctcg atcatctatc gcatgacaga acacggtttg aagctagtta
     9781 atttagaaga tttataaatt tgcaacatag cagataggtg gggcaaaaac acaattttag
     9841 gagaaaaaga agtaaatctt cccatagtaa aacgcataat atcaagtttt cacacctgat
     9901 attatgcgtt tttcagattt taaagacttt tttccagcct tcattttaca tatgttttaa
     9961 acgttcaatc cgttctgaga taggtgggtg ggtataaaag agtttttgga accccccacc
    10021 tttcttggga tcattgatat aaagggcact gctagcatca tcgacgtggc gactcatagg
    10081 tttgctattg tccaacttat ctagggcatt aatcattccc tggggattgc gagtcagctc
    10141 gacactagat gcatctgcca gaaattccct ctgacgagaa atagcgagct gaaccaaggt
    10201 tgcagcgaga ggtgccagta caatagctag tagggaaacc actagcataa tgatttcaag
    10261 accatttcca tctcggtcat catcacttcg tctgcgacct gctccacccc accacatcat
    10321 acgacctgcc atactagaaa gcatggtgat agcactagca agggcaactg caatagtcga
    10381 aatacggata tcataattac gaatatgact gacttcatgt cccataacag cttctagttc
    10441 ttcacgattc atgatagcta gtagacctga agtcgcagca acagccgcat tttgaggatt
    10501 agaacctgtc gcaaaggcat ttaaggctgg atcatcaatg atgaaaacac ggggcatagg
    10561 aatctgagcg accagagcca tatcttccac tacatggtag aggtctggtg ccgtttgctc
    10621 atccacctca cgcgctccat tcatggacat gacaatctct gtcgattgaa aaatcataga
    10681 caaagcgtag ataaagccga taatcagtgc gataaccaaa ccaccaagtc cagatcttat
    10741 aaagagataa ccaaccgcat aaccaacaag agctaagagt aggaaaaata ccagcaacaa
    10801 aatccaggtt tttcgtttat tgcttgcaat ttgatcaaac aacatcttag tcacctaaac
    10861 cgctaaaatc aactttagga accgactttt cctcttcagg tgtttgaagg aaatctgccg
    10921 ctttaaatcc aaacattcca gcgataatat tgctcgggaa agtttctaat tttacattgt
    10981 agttgctgac aacactgtta tagagttgac gagagtaaga aattttattt tctgtgtttg
    11041 tcaactcctc ttgcaattta acaaagttag cactagcttt caaatctgga tagctttctg
    11101 caactgcaaa aatacctgaa acctgacgag tgagggcatc actggctttc atagcttctg
    11161 ctggtgaagt cgctgccgcc acttggttac gtagttctgc caccttttca agggtagaac
    11221 cttcatattt ggcataacct tttacagtct caatcaagtt tggcaagagg tcatttcgac
    11281 gtttcaactg aacatcaatc tgactccaag cctccttggt ttgcatacga tttttaacca
    11341 aaccgttata gctaacaatc acaaaaataa caacaagagc taaaactcca agaataatcc
    11401 aagtcataat ataagtcctt tctgctttta gattagtacc agtatatcaa attttctatg
    11461 attgtggtaa aataagatga tactaaagaa ggaaataact atgaaaccaa aaacatttta
    11521 caacttgctt gccgagcaga atcttccact ttcggaccag caaaaagaac aatttgaacg
    11581 ttattttgag ctcttggtcg agtggaatga gaagattaat ttgacggcga ttacggacaa
    11641 ggaagaagtt tatctcaaac atttttacga ttcgattgca cccattcttc aaggtttgat
    11701 tcccaatgaa actatcaaac ttcttgatat cggggctggg gcaggatttc ctagtctacc
    11761 aatgaaaatt ctctatccgg agttagatgt gaccattatt gattcactca ataagcgcat
    11821 caacttccta caactcttgg ctcaagaact ggatttgaac ggagttcatt tctaccacgg
    11881 acgtgccgaa gattttgccc aagacaagaa cttccgtgct caatatgatt ttgtaacagc
    11941 tcgtgcggtt gcccgtatgc aggtcctatc tgaattgact attccctacc ttaaggttgg
    12001 tggcaaacta ttggcactca aggccagcaa tgcgcctgag gaattattag aagctaagaa
    12061 tgccctcaat ctccttttta gtaaggtcga agacaatctc agctacgccc taccgaatag
    12121 agatccgcgc tatatcacag tggtagaaaa gaaaaaagaa acaccaaata aatatccacg
    12181 taaggctggt atgccaaata aacgcccact ttaaattttt tagtaaacaa atgtttacaa
    12241 aatcagcctc gctcttttat ttctaggctc gggaaaaaat gatttacaaa atcatttttt
    12301 tctgctatac tatcctaagc aaaggttttt aatgtcatcc cgtgaggtga cgaagacgca
    12361 aaaatatttg aaactcttta aagtctagat tttagagaag tcttactctg agggcctatt
    12421 gctgtaaaat aatgggctct tttctgatgc ccaaaagtga ggtttatatg aaacaagaat
    12481 caactgttga tttgttacta gacgttgacc aacgtccttc ggatggaaaa ggaattctcc
    12541 ttagcttcca acacgttttc gccatgtttg gtgcgaccat cttggtacca ttgattttgg
    12601 gaatgcctgt atctgttgcc ctttttgctt caggtgttgg aacactcatc tacatgattg
    12661 ctactggttt taaagttcca gtttatctag gttcttcatt tgcctttatc acagctatgt
    12721 cactggctat gaaagaaatg gggggtgatg tatctgctgc ccaaacaggg gttatcttga
    12781 ctggtttggt ctatgtcctt gttgctacca gcatccgatt tgtaggaaca aaatggattg
    12841 ataaactctt gccaccaatc attatcggtc ctatgatcat cgttatcggt cttggacttg
    12901 caggttcagc tgttaccaat gcaggtcttg tagcagacgg aaattggaaa aatgctctgg
    12961 tagccgttgt tactttccta attgctgcct ttatcaatac aaaaggaaaa ggcttcctac
    13021 gaatcattcc attcctcttt gccattatcg gtggttacct tttcgcacta actcttggct
    13081 tggttgactt tacaccagtt cttaaagcca actggttcga aattcctggt ttctacttgc
    13141 catttagcac aggtggtgcc tttaaagagt acaatcttta ctttggtcca gaagccatcg
    13201 ctatcttgcc aatcgctatc gtaacaattt ctgaacatat cggagaccat actgttttgg
    13261 gtcaaatctg tggccgtcaa ttcttaaaag aaccaggtct tcaccgtact cttattggtg
    13321 acggtatcgc aacttctgtt tctgccttcc ttggtggacc agccaataca acttacggag
    13381 aaaatacagg ggttatcggt atgactcgta tcgcttctgt ctcagttatc cgtaacgctg
    13441 ccttcatcgc gattgccctc agcttccttg gtaaattcac tgccttgatt tcaactattc
    13501 caaacgctgt acttggtggt atgtcaatcc ttctctatgg ggttatcgcc agcaatggtt
    13561 tgaaagtctt gattaaagaa cgtgttgatt tcgctcaaat gcgaaacctc atcatcgcaa
    13621 gtgctatgtt ggttcttgga cttggaggag ctatccttaa acttggtcca gttacacttt
    13681 caggtactgc cctttcagcc atgacaggaa tcatcttgaa cttgatcttg ccatacgaaa
    13741 ataaagacta agagtctaaa tacacctaat ccactcagac agctgagtgg atttttcgca
    13801 taccataata aaagtgtctt aacaaaatta ttaaaatcaa aaaacgtata atatcagata
    13861 ttctaaaacc ttgatactgt acgttttatc atagaaattt ttactttatt ttctcatcaa
    13921 atgagatttg catcaatctc ttgtcttact tgcgtttctt cttcgctttc ttcattttgt
    13981 tagccatacg tttcatggac tgtttcatgg caaattcacc aattttacct ttcaaaccgc
    14041 caccaaacat ctggctcata tctggcattc ctgctcctcc gagagctgat aagtcaggca
    14101 taccgccttg tcccatcatt ccttcaaggg cagacatatc cattcctccc atatttggca
    14161 tatttttagg aaggttattt ggattaatcc ccatttgctt catcatttta ttcatatccc
    14221 cagacataac accctgcatg agctgtttag cctggttaaa gtccttgatg aatttattga
    14281 cttcgacgaa tgtatttcca gaaccagcag caatacgacg gcgacggctt ggatttaaca
    14341 aatctgggtt ttcacgctct tcaggtgtca tcgaagacac aatggcacgt ttacgagcaa
    14401 tctggcgttc atccaccttc atgttttgaa gggctggatt gttggccata cctggaatca
    14461 tcttgagcaa gtcttccatc ggccccatat tttgcacctg atctaattga tcgatgaaat
    14521 cattaaaatc aaaggtgttt tcgcgcatct tctcagccat ttcaagggct ttttgttcat
    14581 cgtattcctg agaagctttc tcaatcaaag tgagcatatc ccccatacca aggatacggc
    14641 tagacatgcg gtctgggtgg aaggtttcaa tgtccgtaat cttttcacct gtaccagtga
    14701 acttgattgg ttttccagta atgtgacgaa cagacagagc agcaccacca cgagtatcgc
    14761 catcaatctt ggtaaggatg accccagtca cttccaactg agcattaaac tcacgcgcaa
    14821 cattggctgc ttcctgacca atcatagcat caacgacaag caagatttca tttggttgag
    14881 ccaatgcttt cacatcacga agctcattca tgaggagctc atcaatctgc aaacgacccg
    14941 cagtatcaat caagacatag tcgttatgat tagtttgggc ttgctccaaa ccttgacgta
    15001 caatctcaac agctggtact tctgttccaa gtgcaaagac aggcacatca atctgttgtc
    15061 ccaaggtctt aagctggtca atggcagctg gacgataaat atccgccgca atcatcaaag
    15121 gacgagcatt ttcttctttc ttgagtttgt tggccaattt accagcaaag gttgttttac
    15181 cagccccttg taaaccaacc atcatgatga tggttggaat cttaggtgac ttgataattt
    15241 ctgccgtatc agaacctaaa acggctgtca gttcttcatc aacgatttta ataatctgtt
    15301 gcgcaggatt aagcgtatca atgacctcat gcccgactgc acgctcacga actttcttga
    15361 taaagtcctt tacaacaggc aaggcaacgt cggcctcgag caaggccaag cgaatttctt
    15421 tggttgcctc ttggacatca gattcagaga tttttccttt tttacgtaga tttttaaaga
    15481 cgttctgcaa acgttctgtt aaactttcaa atgccatttt tcttcctctt attctctatt
    15541 atcaatgctt gttaaaattt ctatctgctc ctgcagaaag tcatccttgg gatagcgctc
    15601 caaaatctga tcaaaaatct gactgcggac aatatagtcc gagtacatgt gcaatttcat
    15661 ctcataatct tccagaatct tttctgttcg cttgatattg tcatagacag cctgacgact
    15721 gacaccgaac tcctcggcaa tttcagcaag gctgtaatca tcagcgtagt agagctcgat
    15781 ataattcatt tgcttatctg tcaaaagcgc cgcataaaat tcaaagagcg cattcatacg
    15841 attggttttt tcgatttcca taacttttat tataccaaaa attagcctaa tctaccacac
    15901 taggaagccg atccaagaag atagatagct aaatttgaaa aagacatgag cctagcccca
    15961 agtaatttcc aattgatagc tggcaaaggg atgtccctct tgattttgta gttgataatc
    16021 tagttcaatc ttttgcctat caacttgata atggctcgtt tggatggtaa actcctgcat
    16081 gcccataggt gtaagaatat aggctaaact atcgctatcc tttagaaagc gcataatggt
    16141 cttgggatta gaaaatcggc tcatcacaag ttcttgacca tgaaatttaa tcactacttt
    16201 ttccttttcc tcattataga aaagcaggta gctataatct cttttttcat gcacttccac
    16261 atcataaagc tggtcaatca cttccaactg ctcatcaaac tgaatcgtat ttcgcatccg
    16321 aatcttcaca tcaggccctc tttcttgtct cttgtcctac tattttacca aaaagagcag
    16381 gattttgcta taatggtcat atgaacgaaa aagtattccg tgacccagtt cacaactaca
    16441 tccatgtcaa taatcaaatc atctatgact tgattaatac aaaagaattt cagcgtttgc
    16501 gccggatcaa acaactggga acttccagtt ataccttcca cggtggagaa cacagtcgct
    16561 tctctcactg tctaggagtc tatgaaattg cacgacgcat cacagagatt ttcgaagaaa
    16621 aatatcctga ggaatggaat cctgccgagt ctctcttgac catgatcgct gctctcctac
    16681 atgaccttgg gcatggcgcc tactcccata cttttgaaca tctctttgat acagaccatg
    16741 aagctattac tcaggagatt attcaaagtc ctgagacaga gattcaccaa gtcttgctac
    16801 aagtagcgcc cgattttcca gagaaagttg ccagtgtcat agaccatacc tatcctaaca
    16861 agcaggtcgt acaactcatt tctagtcaga ttgacgcaga tcgcatggac tatctcttgc
    16921 gtgactccta ttttacagga gcatcctatg gggaatttga cctgactcga atcctccgag
    16981 tcattcgtcc tatcgaaaat ggtatcgcct ttcagcgcaa tggcatgcac gccatcgaag
    17041 actatgtcct cagtcgctac cagatgtata tgcaggtcta tttccaccca gcaacacgcg
    17101 ctatggaagt tctcctacag aatcttctca agcgcgctaa ggaactctac cctaaggaca
    17161 aagacttctt tgcacgaact tccccacacc tcctgccttt ctttgaaaaa aatgtgacct
    17221 tgtctgacta tctggctcta gatgatggtg tgatgaatac ctacttccag ctctggatga
    17281 ccagtcctga caaaattctc gcagatttat cgcaacgctt tgtcaaccgc aaggtcttta
    17341 aatccattac cttttcacaa gaagatcaag accaactcgc tagcatgaga aaattggttg
    17401 aggacattgg ctttgatccc gactactata ctgccattca taagaacttt gacctccctt
    17461 atgatatcta tcgtcccgaa tctgaaaatc cacggacaca gattgagatt ttacaaaaga
    17521 atggagaact ggccgaactc tctagcctgt ctcctatcgt ccaatccctt gctggtagtc
    17581 gtcacggaga taatcgtttc tattttccga aagaaatgtt agatcaaaac agtatctttg
    17641 ctagcattac ccagcaattt ttatacttga ttgagaacga tcattttacc ccaaataaaa
    17701 actagaagag gaaatttatg agtattaaac taattgccgt tgatatcgac ggaacccttg
    17761 tcaacagcca aaaggaaatc actcctgaag ttttttctgc catccaagat gccaaagaag
    17821 ctggtgtcaa agtcgtgatt gcaactggcc gccctatcgc aggcgttgcc aaacttctag
    17881 acgacttgca gttgagagac gagggggact atgtggtaac cttcaacggt gcccttgtcc
    17941 aagaaactgc tacaggacat gagattatca gcgaatcctt gacttatgag gattatctag
    18001 atatggaatt cctcagtcgc aagctcggtg tccacatgca tgccattacc aaggacggta
    18061 tctatactgc aaatcgcaat atcggaaaat acactgtaca cgaatcaacc ctcgtcagca
    18121 tgcctatctt ctaccgtacc cctgaagaaa tggctggcaa agaaattgtt aaatgtatgt
    18181 ttatcgatga accagaaatt ctcgatgctg cgattgaaaa aattccagca gaattttacg
    18241 agcgctactc catcaacaaa tctgctcctt tctacctcga actccttaaa aagaatgtag
    18301 acaagggttc agccattact cacttggctg aaaaactcgg attgaccaaa gatgaaacca
    18361 tggcaatcgg tgacgaagaa aatgaccgtg ccatgctgga agtcgttgga aaccccgttg
    18421 tcatggaaaa tggaaatcca gaaatcaaaa aaatcgccaa atacatcact aaaacaaatg
    18481 acgaatccgg cgttgcccac gccatccgaa catgggtact gtaaaaggaa agaatagact
    18541 aaaaccgctc agctgagcgg tttttgatgt ctaattacat gccccctgca ggaatcgaac
    18601 ctgcaactac tccttaggag ggagttgtta tatccattga actaagggag ctagataaaa
    18661 actctgctga aaaagcagag ttttttagtc gaattaacga cggatttctt tgatacgagc
    18721 tgccttacct tgaagagcac gcaagtagta caatttcgca cgacgtactt taccgtaacg
    18781 tacaacttcg attttttcaa cacgtggagt gtggattggg aagatacgct caacacctac
    18841 accgttagag attttacgaa ctgtgtagtt ttctgagatt ccagcacctt tacgtgcgat
    18901 aacaacacct tcaaaaatct ggatacgttc acggttacct tcgacaactt tcgcatgtac
    18961 acgaacagtg tcaccaggac ggaatgatgg gatatctgta cgaagttgac cttcagtcaa
    19021 gctttggatt aatggattca ttttattctc ctatctttgt caatcttgag gaatcttcct
    19081 cagcggataa actgtatttt tgtgcgtcca ttacacacaa gatatagttt accaaatttc
    19141 taaaaaaaag taaagaaatt tatagcaaaa ttcctaaaaa aatcgcaacc aaaccaccta
    19201 tgtaagtcaa agtcaggtaa gaataaaaga ccttcttatc acttagcagt ctttgaagtt
    19261 cgtcattcaa ggtcgaaaaa gttgttaaac cgccacaaaa tcctgttgct agaatagcat
    19321 atacttcctt agactctaca tgattgtaaa atactccaat taaaaaacaa cctaaaagat
    19381 tagctatgag cgttccgagt ggcaatttag aagcttgatt atagcgagaa aagaaatacc
    19441 gtacgagtgc tcccaagcca caggcgattg caagatagac gattaccatt tcttcctccc
    19501 tagaaaataa gctaagagta ggcctccacc gatgctcaaa agcaaataca ggactaaact
    19561 aaaataacgc cctgtatcaa gcagcttcac agtatcaagc attaggctgg aaaaagttgt
    19621 taaacctccg caaaaacccg tccccagtgc taaaatcaag cccttactag tccccttata
    19681 gaccagatag cccttgacaa gaaaaatcaa gcagaaaatt cccagatagt tgacaaagag
    19741 agtgccccaa ggaaagtctg gactggctgg taaccaggtg gaaactagat atcggacaag
    19801 tccgcccaac atagcagcta gaaaaattcc tagcggataa aattgttctt ttttcatttg
    19861 atattttgat cctgataatc acgcgaacgt ttgagtatgt ccgaaaaagt cgctacaata
    19921 gtctcctgat agcgcttgtc ctctacacga ctcccaacct tttcaaaaat aacttcttct
    19981 ctcttagtat ctaaaatcgg tttacctgaa gctttcttat aagcaaccac cccctcaact
    20041 aaatgcattc gttcttctaa cagtttgaca atttggtcgt cgatttgatc gatttcttga
    20101 cgaataatat ctaaatccat acagtctcct cctttatttg aattattgta tcaaaaagcc
    20161 atcaattagg ctagtaaaat cccaactctc gataagaaaa atgcactgat tgattacatc
    20221 agcgcacttt tatgcttatc ctactttagc aaccaattct tctgcgaatt gttccaagcg
    20281 ttcaatatct tcttcctcgg cagaaagatc aactttgaca cactcagaac ctttttctgc
    20341 tcctgttgaa acaaagacac ggtcaaagtc atcaacagcc ttacagaatt catcgtagaa
    20401 ggtatctcct gagccgacca ctccgtagat tttgccattc aagttgagat ctgctagatc
    20461 ttcgtagaag tccatcatct catctggcaa ttcaccatca ccataagtat aggtcgcaac
    20521 gatagcgatg tctgcttcca agaagtctga agcgtcaaca gttgtacatt catcaacatc
    20581 aacatccaag cccaagtcac gtaatttgtc tgctacaata tctgcaattt cttcggtatt
    20641 accggtcata ctggcaaata caatttttgc taatgccata tcgtcctcct caatttatct
    20701 ttctccatta tatcacatct ttttcatttt aaaaataaaa attcttgtgc tacaatgaaa
    20761 tgagaaagaa ttgaggttat ttatggagat ttgccaacaa attttagaaa aaattaaaga
    20821 atacgacacc attatcattc atcgtcatat gaaaccagac cctgatgcct tgggaagtca
    20881 ggtgggattg aaagccttgc tggaacatca tttcccagaa aaaaccatca aagccgtcgg
    20941 ttttgatgaa ccaactctta cttggatggc tgagatggat cttgttgaag atagagccta
    21001 ccaaggcgca cttgtcatcg tctgtgatac agctaatact gctcgtatcg atgataagcg
    21061 ctatagtcaa ggtgattttc tcattaagat tgaccaccat ccaaatgatg atgtatacgg
    21121 tgacctgtct tgggtcgata ctagttcaag tagcgctagc gagatgatta ccctatttgc
    21181 ccaaacaacc caactagcct tggcagatcg cgatgctgag ttgctctttg caggaattgt
    21241 cggtgataca ggtcgcttcc tctacccttc taccactgca cggactcttc gcctggctgc
    21301 ttatttgaga gaacataact ttgactttgc ggctctcact cgcaaaatgg acactatgag
    21361 ctacaaaatt gctaaactgc aaggctacat ctacgaccat ctggaagtgg atgaaaatgg
    21421 tgctgctcgc gttatcctga gtcaagaagt cttgaaacaa tacaatgtaa ccgatgctga
    21481 aactgcagcc attgtcggtg cacctggacg cattgacaga gtgagtctct ggggaatttt
    21541 tgtcgaacag gctgatggcc actaccgagt tcgcttacgc agtaaaatcc atcctatcaa
    21601 tgaaattgcc aaggagcatg atggtggagg ccaccctcta gcaagtggtg ctaattccta
    21661 tagcctagaa gaaaacgaaa tcatctacca aaagttaaaa aacttgctta aaaactgata
    21721 aaatacttgc caaacttttc agaatctgat agactagtat ggtaacaatc tatggctcgc
    21781 aaagagacca tggcagaaag gaaatattgc aaaatgaaaa aagatatcca tccagaatat
    21841 cgcccagttg tcttcatgga cacaactact ggttaccaat tccttagcgg ttcaacaaaa
    21901 cgctctaacg aaacagttga gttcgaaggc gaaacttacc cattgatccg tgtggaaatt
    21961 tcatcagact cacacccatt ctacactgga cgtcaaaagt tcactcaagc agatggacgc
    22021 gtggatcgtt tcaacaaaaa atacggtctc aaataatgat aaaagaacag tttcgactgt
    22081 tcttttttgt ttcttgaaat caactgctgt tttcatgttc cagactcatc tgtaggttcg
    22141 gtttccatgc tactaggcag gaaggaaata gctgtttcaa cacgtccata atgagctgta
    22201 ctattgtcac gaaccacact ttcattgatg gtccaagtgg aattcatttt cttaaaagct
    22261 tctcggactt tttccaaatc tttggaggca atggcctgct ctaaggtttc aaaacgagga
    22321 cttatactca tctgctttca caaagcattc tagtccatct ccgattaacg atggacttta
    22381 tcacctcctt ctccagtcct tgtataacat cttggagttg attcatgaca tcttccaaag
    22441 ttcgaaaggc tttattctta aatccacgtt tacgaatctc tttccacact tgttcaatgg
    22501 gttcatctct ggtgtgtatg gaggaataaa ggtaaaatca atattagtcg gaatatttaa
    22561 ggtacttgat ttatgccata tagcattgtc cataacgagt aaaaggataa gcttgtgaaa
    22621 gctcttctaa aaaggcgttc atccacactc ctttttataa gcctgaaata aggcatcaat
    22681 tgtaacaaat tctcctgcct ctgcagcctt caaatggcga gcaagaaagg ctttctcttc
    22741 ctcaactgtc atatatgcat gattacgacc accacgtgtt tcttgaagga gagagtcgag
    22801 tccgaactcc tcatattttt ttacatttcg ccaaatcgtt gtttgattac agtctaaaag
    22861 ttctataatc tctttataag atttgcccat cagacgaaat atagtagatt gaaactagaa
    22921 tagtacacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg
    22981 ctctgttctt gtttcgt
//
LOCUS       DAVHSH010000027        22489 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000027 DAVHSH010000000
VERSION     DAVHSH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.027"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            77..528
                     /locus_tag="VVR08_001228"
                     /pseudo
     CDS             77..528
                     /locus_tag="VVR08_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            693..992
                     /locus_tag="VVR08_001229"
     CDS             693..992
                     /locus_tag="VVR08_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU6075145.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1253..1576
                     /gene="tnpB"
                     /locus_tag="VVR08_001230"
                     /pseudo
     CDS             1253..1576
                     /gene="tnpB"
                     /locus_tag="VVR08_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(2305..4032)
                     /gene="ezrA"
                     /locus_tag="VVR08_001231"
     CDS             complement(2305..4032)
                     /gene="ezrA"
                     /locus_tag="VVR08_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU6075146.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNTEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4114..6060)
                     /gene="gyrB"
                     /locus_tag="VVR08_001232"
     CDS             complement(4114..6060)
                     /gene="gyrB"
                     /locus_tag="VVR08_001232"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU6075147.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6075..6638)
                     /locus_tag="VVR08_001233"
     CDS             complement(6075..6638)
                     /locus_tag="VVR08_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6075148.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6723..7277)
                     /locus_tag="VVR08_001234"
     CDS             complement(6723..7277)
                     /locus_tag="VVR08_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU6075149.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7288..8511)
                     /locus_tag="VVR08_001235"
     CDS             complement(7288..8511)
                     /locus_tag="VVR08_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6075150.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8548..10998)
                     /locus_tag="VVR08_001236"
     CDS             complement(8548..10998)
                     /locus_tag="VVR08_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU6075151.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11198..12127)
                     /locus_tag="VVR08_001237"
     CDS             complement(11198..12127)
                     /locus_tag="VVR08_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6075152.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            12267..12554
                     /locus_tag="VVR08_001238"
     CDS             12267..12554
                     /locus_tag="VVR08_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU6075153.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12588..13922)
                     /gene="ciaH"
                     /locus_tag="VVR08_001239"
     CDS             complement(12588..13922)
                     /gene="ciaH"
                     /locus_tag="VVR08_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU6075154.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSFNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13912..14586)
                     /gene="ciaR"
                     /locus_tag="VVR08_001240"
     CDS             complement(13912..14586)
                     /gene="ciaR"
                     /locus_tag="VVR08_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU6075155.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14695..17241)
                     /locus_tag="VVR08_001241"
     CDS             complement(14695..17241)
                     /locus_tag="VVR08_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU6075156.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFFAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLTAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17364..17804)
                     /locus_tag="VVR08_001242"
     CDS             complement(17364..17804)
                     /locus_tag="VVR08_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU6075157.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(17779..18648)
                     /locus_tag="VVR08_001243"
     CDS             complement(17779..18648)
                     /locus_tag="VVR08_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU6075158.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18626..19126)
                     /locus_tag="VVR08_001244"
     CDS             complement(18626..19126)
                     /locus_tag="VVR08_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6075159.1"
                     /translation="MEIKKHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(19137..19835)
                     /locus_tag="VVR08_001245"
     CDS             complement(19137..19835)
                     /locus_tag="VVR08_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU6075160.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19828..20064)
                     /locus_tag="VVR08_001246"
     CDS             complement(19828..20064)
                     /locus_tag="VVR08_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU6075161.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(20164..21090)
                     /locus_tag="VVR08_001247"
     CDS             complement(20164..21090)
                     /locus_tag="VVR08_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU6075162.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21165..21980)
                     /locus_tag="VVR08_001248"
     CDS             complement(21165..21980)
                     /locus_tag="VVR08_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075163.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21984..22304)
                     /locus_tag="VVR08_001249"
     CDS             complement(21984..22304)
                     /locus_tag="VVR08_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6075164.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6831 a         4870 c         3985 g         6803 t
ORIGIN      
        1 gattatacca cattgtgtac tatttttggt tcatttcact ataataataa cgatactaga
       61 taatgaggaa aatgcaatgg caaacccaac tttcggagaa aaaaagtgaa tacagactat
      121 attgctcgct atggcgtata tgcagttatc cctaatcctg aacaaaaaca aattgttctt
      181 gttcaagaac caaatggtgc ttggttccta ccatgtggaa aaattgaagc aggtgaaaat
      241 catcaggaag ccctaaagcg tgagttgatt gaagagcttg gtttcacagc agaaattggt
      301 acctattacg gacaagctga cgaatatttc tattctcgtc atcgtgatac ctactactac
      361 aatcctgcct acctctatga agcaactcct ttcaaagaag tacaaaagcc actagaaaac
      421 tttaatcata ttgcctggtt ccctattgac gaggctatca aaaaccttaa acgtggtagc
      481 cataaatggg ccattgaatc ttggaaaaaa cagcataaga ttggctaata ctcttcgaaa
      541 ataaaattca aatcacgtaa gcgtcgcctt accgtactca agtatagcct gcggctagct
      601 tcctagtttg ctctttgatt ttcattgagt ataaatcaag cgactttatt caaaaagtgt
      661 tataatagaa ttagaaaatc ggaggaaata ttatgaagct tatcaatacg acaaactcac
      721 actcgcaact tgtaaaaagt caactagaaa gtaccgatgc aacccttgtt gaggtttatt
      781 ctgcagggaa tacagatgtt atttttaccc aagctccgct tcactatgaa atcctcatct
      841 caaacaaaca ccgtgctatt cgtgagcctg aaatcgaaac cattcaagaa tttttcttga
      901 aacgtaaaat tgataagacc tctgttgatg aagccaatat caagacactc tactcagaga
      961 aattaattgg aatttcaatc ccaatcaagt aagaaaattg agtaaaaact cgatttgaga
     1021 gaaagtccaa taagtctttc cataacaaaa cgcatagtaa caagagtttc tacacccact
     1081 attatacgtt tttatcattt tgaaatctgc tgctaatcaa tgaagaagca aagattaaac
     1141 taggcagcta gttacaagtt acgtaagcgc gtcataacaa ggtatctatc ctaattcccc
     1201 aacttccagt atactagata aaaaataatt atcagaggaa aggtattgta ctatgatgat
     1261 tctactaagt gatttaggtc aagttcacct tgtttgtggc aagacagata tgaggcaggg
     1321 aatagactca ttagcctatg tagttaaaac ccactttgaa ttggatcctt tctccggtca
     1381 agtctttctc ttttgtggtg gacgtaaaga ccgctttaaa gccctttact gggatggtca
     1441 aggattttgg ctactatata aacgctttga gaacggaaaa ctgacttgac caagtacaga
     1501 aaaggatgtc aaagctctca caccagaaca agtagactgg cttatgaagg gcttttctat
     1561 cactccccaa atatagtgga tttaaactag aatagtacac ccctacttct aaaacattgt
     1621 tagaaatcga tttgactgtc ctgatcaatt tgtcctgttc ttgtttcatt ttactataga
     1681 acgatttgaa ggcgtttatg atatttagct gtacgagagt cttttaaaag tgttttgatg
     1741 gtttggattt cttctttagt tgatttcata tcactattgt ataatgcttt ttgattttag
     1801 tctagtataa atagcgagaa atatctatcc tatcttctag aatgtcttcc aaacgaggaa
     1861 actctcgtaa acaaagaggt tttagaggcc tatttaccgt ggactaaaat tgtacaagaa
     1921 aagtgcaaat aagaaatctc cagattagga actatccgtg agttctctag tctggagatt
     1981 tttcaataga cttcgttatt ggacggttac caagttactc aaagtacaga tttgaagctg
     2041 cagataagac tgacgaaatc actttaatac taaatgaaaa tcaaaaagca aactaagaag
     2101 ctagcctcag gctgtacttg agtacggtaa ggcgacgctg acgtgatttg aagagatttt
     2161 cgaagagtat aaaacactgt tttgaggtgg tggataaatc ggctgggtaa aaactcaatc
     2221 tcaggagaaa atgaagtaaa tctccccaca actatagaaa aagatttgat tctgctcctc
     2281 acacaataaa atctttttct tttattaaaa acgaatcgtt tcacgtgttt tctcatatga
     2341 ggtaacaaag cgattagtta caccaggctc tgccacttcc aatgcttgag aaatcttgtc
     2401 aaatgaagcg tgataatcaa attctttttc aaaaatatct aaagcttcgt taaatgcttc
     2461 ttgaatgcgt tcatcaaatg agcgatagcg gttagaatat tgcaagagtt gctctgtcaa
     2521 agttgcatat tgtacaatat tataagtttc cgtttctaaa gcttccatat cattcgttgc
     2581 aatttcaaga actcgggtaa cagattcaat gttaatcatt ttttgttcta actcaaccat
     2641 taaatcctcg gtattattgc ttgccgtaaa gaataacttc aagaaagttt gtggaatacc
     2701 tggcagattg cgtttttcca tgtatcgctt gatagtatgg agacgattga cataaacatt
     2761 ggccttttga cgtgcattaa tatcatcttt ctcaatttgt gtcaggcgct cactaactga
     2821 aatttgctca tcttcaatat cttttagttg agtttgtaaa tcctcaagat tttcttcaag
     2881 aactgaataa gcttgggttg gttcttcttg atttgaagtt acctcaacaa tagctgcctc
     2941 aaaactctct aattctgtct gaatacgacg aacatggctt gcagctgtct caggaagtaa
     3001 ataggtcttg ttcaaacgtg caatatcttc tcccaataaa gtattattct ctttcatatg
     3061 ttgaagataa gttggaagag ttgcaagtag attttccact actttctgag cagcaatttc
     3121 tcgagtaaaa atatcataca aggcattgat ttcctcttgt gcctgtccat tctcatattc
     3181 ggtattatcc aattccaact gacgaatatt ctcttggttt ttcttgaatg cttcataaag
     3241 caagtggaaa cgcgcttcaa tatccgtttc aacaaaatga taattagcat caattagttt
     3301 acgataaccg gcttccaaat cctgtaattg atctggcaat tctgtagaaa gcgtcgtaac
     3361 caaggctgga acacgatcca caatatgact taaggccaaa atgtgatttt ctgtattatc
     3421 caaaatcact gcggcttcca cagggtcacc cgatgaattc aaggttacaa attgtgaaaa
     3481 ttcagattgg atattttcta attgtttttc aatttcatcc aaggcttgac catactgttc
     3541 tgaattttca gcaactctat gctgaagttc ctcaaataaa tccaaagcat gaagaacacg
     3601 accactattt ttagattctt gcttctctaa gtctgccaaa gcattgcgaa ttgccgcaat
     3661 atcttcttca atcaaagtaa tttgactctc aatttggtca atttgatgac tggccttgag
     3721 aaaacgaaat gaatggttat aaccttctgc ttcaaagaga ttattttcaa tatcggcaaa
     3781 agagttgaga gataaatcga cccatttttg attccattca cggaaagcca cttgactttg
     3841 tccaatcaag tgcatatttt ttacagcttc tacttcatca tttactggaa gattgtatag
     3901 ttcttctttt ctttcttcta gcgcctctaa tctcccctcg tttcgcttac gtagaaagat
     3961 tgccactaca taagccagaa ctaaaatgac tgcaattgca accattaaat aaattagttg
     4021 tccattagac atatcaaact ccttttttac ttgaaacaat cgtaacgatt atatcatatt
     4081 ttttagacca agggaactac ttctccctat tttttagaca tcaagtgtac tatagacagc
     4141 attttcttcg ataaactcac gacgaggctc tactcgatcc cccatcaaca tatcaaagat
     4201 tttatctgct tctgcagcat catctacaga aactctagcc atcaagcgat gttcgggatc
     4261 catggttgtt tcccacagct gatgatcgtc catttcacct agccccttat aacgctgaat
     4321 agtcggtttg gtacgacctt cactataacg ggctaaagct tcttggagtt tgatttcttg
     4381 atctgcaccc ggctggatat attctttaat ctcgcttcca accttgacac catagattgg
     4441 tggttgggca atataaacat aaccagcttc taggattggt ttcatataac gataaatcaa
     4501 ggttaaaaga agggtacgaa tgtgggctcc atcgacatcg gcatcggtca tcaaaacgag
     4561 tttttggtaa cgggctttcg aaacatcaaa ttctgcgcca aatcctgttc ccatggctgt
     4621 gaaaagacta cgaatttctt cgttggctag aatcttatcc atacttgctt tttcaacatt
     4681 caaaatctta ccgcgaattg gaaggatagc ctgaaactca cggttacgac cagatttggc
     4741 tgatccacca gctgagtctc cttcgacgat gaagagttct gtttcagcag ggttattaga
     4801 agaacagtct gctagtttcc ctggaaggtt ggaaatttcc aaaccagatt ttttacgtgt
     4861 gacttcacgc gcacgcttgg cagccacacg agccttggca gctaaaatcc ctttttccac
     4921 gatacgtttg gcaatctgtg gattttccat gaggaaatcg gagaaggctt cactgaagag
     4981 gcgattggta atcttgacca cttcgctatt tcccaatttg gtcttggttt gtccttcaaa
     5041 ctgtggattt gggtgtttaa ctgagataac tgcagttaag ccttcgcgaa catcttcccc
     5101 tgttaggttg tcttcattgt ctttcagtaa cttattttta cgagcataat cattgataac
     5161 acgtgtcaag gctgtacgga aaccttgttc atgcgttcca ccttcatgtg tatgaatatt
     5221 attggcgaaa ctcatgacat tttcatggta accagttgtg tactgcatgg ctacctcaac
     5281 tgtgatatca tccatctcac cgtctgtata gattggtgta tcaaagatta catccttgtt
     5341 ctcgttgata tattcaacgt aactagcaat cccaccttca taatgataat gcttggtttg
     5401 ttccaaacct tcacgcttat ctgtaattga aatttgaaga ccgcgattta gaaaggccaa
     5461 ctcttgaatc cgtttattta atttatcaaa atcaaagatt gttgtttcag tgaagatttt
     5521 tgggtccggt gtgaagtgaa cagttgttcc tgttttatcc gtatctccaa ctatttcaag
     5581 atctgcgaca acatgaccac gacggtattc ttggtaatga atcttaccat ttttgtgaac
     5641 atgaacgtct aattgagtgg aaagggcatt aactactgac gaccccaccc cgtgaagacc
     5701 acctgaaacc ttgtatccac caccgccgaa ctttcctcca gcgtgaagga ctgtaaagac
     5761 ggtctcaaca gcaggacggc ctgttttttc ctgaatatcg actgggatac cacgcccatc
     5821 atccacaaca gtaatcgaat catctggctc aataaaaact tgaatatggc tggcaaatcc
     5881 tgccaaggcc tcgtcaattg agttatcaac aatttcccag actagatggt gaagaccttc
     5941 ttttgaggtt gatccaatgt acatccctgg acgcatacga acagcctcta agccctctaa
     6001 aacttgaatt tgactggcat cataatcctg tgcctgcaga tttttgattt cttctgtcat
     6061 cttattcctt tttcttatat gtctaatact tgtcttaaat tcacgatact ggtaaacaag
     6121 tgggtatcaa gtcctgcagc ttgacctgct tcgatatcaa tcggccgatc accaatgaca
     6181 agaccagagc taatctgata cttttctctt aaataaagca tggattcggg atttggcttt
     6241 ctcttaaagc ctgagctaga agtcaccact tctgtaaaat aagctgctat agaggttttt
     6301 tctaaaattt ccaaaacctg atcatttcga tgagagacca aaaaatgacg gccaccttga
     6361 tttgaaatga cttccaatag gtcagaaact ccttcaaata aaatcgggtg ttcaagctct
     6421 ctggcttcat tttccttgta cttttctaaa aaattctcta aattgggagc gaatgtctca
     6481 atcgcaaaag gagtagaaac ctttaaagct tgatagacac tgtcatggtc ttgtgtgata
     6541 ccatacagtg ccaatgtttc aacaaatgca gctgttgaag tttcataatt atccagtaaa
     6601 gttccaccta aatcccagat gtaatcgtga tatttcatac ccttcattat agcatttttt
     6661 tatgaaaaaa gcgatgattt ccctgagttt tccacataaa aaacgagaga ataactcccg
     6721 ttttactgat ttttaccaaa gacatctcga tagagcattc ctgttcgtaa actctctgcg
     6781 tcccctccta gttgctccac caactcgtag gcaaaggcaa gggctgttga aggaccccga
     6841 ctggttgtca actgaccatc taccactact gtttccttga cgtagtgacc atcaaggatt
     6901 tgctcttgaa cgccgtcata acaagtgtat cgcttatttt tcaatatctc tgcttgattg
     6961 agggcaattg gtgccgcaca aatggctgct agtttcttcc cttcttgctc gaagctttgc
     7021 aattcttgaa tcaaggtctg attatcacgt aaatgtgcag aaccaggcat acctccagga
     7081 agaacaatca tatcatagtc tgataaatct ccatcaaaga catgatctgc tcttacttgg
     7141 attgcatgcg aacccgttac ttgctcttca aaaccaacca tatcacatgt gatattggct
     7201 cgacgcaaga catctacaac tgtcaaggct tcaatttctt caaagccctg agctaacata
     7261 actgctactt ttaccatgat tttctcctta tttaatttgt tttaatacaa cctttttccg
     7321 tttgaatggg acttttccgc tcttttcttc agctagatta gtctggtaac tcatcgataa
     7381 aagcaaacca acaccaatca gattactgat aatagctgat cccccttgcg aaatgaaagg
     7441 caagggaatc cccgtcaaag gaagtagtcc agtcacagca ccgatattct caaagatgtg
     7501 gaagagcaac atcataatca aacctgtgga aatataagtg tagaactggt tatttgattt
     7561 aagagtaatc ttcaacatac ggtaaatcaa catgagatag agggcaataa ccaggacaga
     7621 gccaataaag ccaaaatctt ctgcaataac cgtaaaaatc atatctgact ctcgaactgg
     7681 gataagcaga ttcgaagcat taaatccctg accaaataag ccaccactcc caatggcaat
     7741 ctgcccttga gcctgctggt aagtcgttgt ttgggcaaac tcaaagggat tgagccaagc
     7801 caaaatccga ttaatttggt aggtcggcat tccaatctgg tgaagaaaag ctcgtccgtc
     7861 cttgctaata aagatagcta agaaaccagc aactcctgtt acagcagtca caaatactgg
     7921 gataataatt ttccaagaaa cccctgataa taaaacgatt cctgagaaaa tggctacaaa
     7981 aaccaaagcc gtccccaagt cactttgaag tgctaaaaga actaggactg gaatggtaaa
     8041 gagaatcatc cagaaaatta acaaaaagtc cagcggaacc gtgcgtctcc attccttatg
     8101 tttctttgta aattggacaa tgacacgagc caacatgagg atataggata tcttcataaa
     8161 ttctgacggt tggaataggg taattccatt tattgatacc cagtttttgg cacccgttga
     8221 tgcaactaag cttggattat aaaatacaat cggcaagatc ataagtccca agcctaaaat
     8281 atatagaaag ggggtcacct tccaaagaaa ttctgtatta aagagcatga ccacaaaacc
     8341 aatcacaagc cccaaggcaa tccaggcgac ctgctgccct aaaatgggca gaatattatt
     8401 gggataatca tgactaacgg ctatatagat agccaccaca ccgatgacca gtagaaaaaa
     8461 tactggcaag agcaaactgt aatcgactct tgagtcgaga gaacgtttca tatatactaa
     8521 ccttatactt tcatacaata ctatttatca aagttcatta aaaaatctat caatagcctc
     8581 gtcaacttcg gatcgagaga tggttttaac agtcgcttct tctgctagag atgctactat
     8641 ttgtttgccg tatcgttttc cgacgattct cctatccaaa ataagagtta aggaacgttg
     8701 gtattcacgt ctcatacttc ttcccaaagc ctgttttaaa cgaataatgg ccattggcaa
     8761 ttgataatca taaaaggcat ttttcccttc ttgattcagt tcttgattaa tctttttcgt
     8821 caagggttct tgaggatttt ggaaaggaag cctcggtaca acttgaatca caaaaggatg
     8881 gcttgaaaaa tcaactccct cccagaaact tgctgcacca agcaagattt gttgttcacc
     8941 tttttcaaag cgtttcttta gctgatgaac atccccattt ttatactggg ccaagtggct
     9001 aactgtaagt aaatccgata ctgctagaag catgtcttta gcggtaaaga gaaccaaaat
     9061 cggttgctgg aaagcttgaa tttccactag taaagcagct acctctctgg catagacttc
     9121 taaggaggtt tctgttacca gagggaaatc tttgaccatg accacttctt gttcctgttt
     9181 tccccgagat tcaatcttga caaatttagc ttcaggatag cctaaaaggt ctgccaaaga
     9241 aaccctctga ctaatctcaa gagtagccga tactcccagg acttggcaac tctcaggaag
     9301 taaagaggac agaagagtac ggcctgattt tgtagaagaa atctgaattt tcttttgact
     9361 cgtttcagtt acttcaagcc agtaatcacc ttcagctgta aaatagcgaa ccagctcatc
     9421 aaagccttct acttctaatt ctgaaaaata ctgatggaga ttatccagag aatctaagat
     9481 atttttccta gatttgccag actgaaattg ttctatcaag tagagacact caaagcgaat
     9541 actttctagt atccgttgtt gaaccctgtt ttcttctcct actaaagcct tatcaattaa
     9601 atcgataata gattgtatat cgtaggtctc ttgaagcaga ttttctagag ctaacaaaat
     9661 cttttggact tcatcaataa tcagtaaacg gtcactgaca aattcaggat tatcttcaag
     9721 tctggtcacg agataggcat gattagtcac taaaagcttg caagtctctg ccctttcttg
     9781 actacgtttc caaaaatctt ccgtcacaaa taagctatgg gatgataaat tcccatcatg
     9841 acgaaggtct gctagaaaat gttggtaacg gtagagttgc ccgatttcat ccaaatctcc
     9901 tgtctctgtc tcagtaagcc agaccaagac ttgcatttta aagcgtctaa ataagcgatt
     9961 ttcatcattt tcctgcaagg aatgataaaa ggcatccaac ttcagataat tttgtggtcc
    10021 ctttaagcta tgaatatctg tatggaacac ttccttgaga cgtttacctt cttcttccat
    10081 gatttgattt tgaagaatct ttgtcggaac actaagaaca atttgtcgct ctttggattg
    10141 agataaagcg ggtaagagat agccataggt tttcccaatc cctgtcggcg cttgaatcag
    10201 agagacaggt tcatctttca atagcaagcc aacctcttta gcaaaacttt cttgttcctc
    10261 cctcacttca aggttcaaca gagaaatatt tttagaaaag tcttgagata gttttcgtag
    10321 ctccagagaa gctgccgttt tcttaaaata cagaccttga acttggacca agtctggaga
    10381 actcaggata gattggttgc gataagtttc ctcaataacc aggtaggact catataggag
    10441 agcgtcagcc atttccagca agcgttccaa gagaccttta ggaagctggg tcatcttttc
    10501 ccgtaaaaaa agaagtaatt ctgctgtagc ttgggcatct gaaagggctg tgtgtgcgtg
    10561 tttaagagga attcctaatt ctcgacacaa aatcggcaag ctatattttt ccagttcagg
    10621 gaaaaagacc tgggccaatt cgaccgtatc aacacgaggg tttcttagct catagccttc
    10681 aaaaaataaa ttttccgcca agagattagc atcaaactga acattatggg ctacaaaaat
    10741 cccatcctcc accaagtcaa agatttttct ggcaacttgc gaaaaatcag gtgcttgcgc
    10801 cagacgttgg tctgtcaatc ctgtcagttc tttgatatga gcatccaagg gttcatgtgg
    10861 attgacatcc gtcgtatagt gatcgacgat ttctccatcc tcaatcacga caattcccac
    10921 ttggataatt ttagccttac tacctgtgct agttgcctct aaatccacca caacatagcg
    10981 attaccaatc gttttcatta taaaaaatta taccaaaaaa agggccattt ggcacctgca
    11041 aacataggat aattttcaaa ctcaagaaca ctacttttct tagaaatccc atcgaataga
    11101 gcattctagc ctgctgattt ttttaaaata gtgaagaaat acgaaaaatt gagagaagaa
    11161 atgttttcat cttccttctc tcaacgaatc atgtatttta tttaaccatg tcaggatcgt
    11221 agtcataaaa tcctgtatca aggaaacggt ttttagggtg aagtttacga acttcttcat
    11281 ccagcaagaa ggcttggtca tggctaaagt tgccctcttg aatcaagcta cgcgcttgga
    11341 taaagagttt tgcaatctca acaaagttct gaccaggagt gtagagccct tctagtttcc
    11401 agcgagtaaa gccatgctcc accaattctg ttaatttgat catcaaatca aggtcattgt
    11461 tggcaaagat atgggtccca tgattatctt caaaaatgga atagtggctc tctggatcac
    11521 ttggctcagc caagaagagg tcacgtttat gcgtcttttc atcatcgata tgtgtaaagt
    11581 tatagtagtt ttgcaagagt ggacgtttag aatgatggat gacgctagca ccgtaaacca
    11641 aaacttcagc aggaatttcc aaaatctctg gcattttgaa aagttcagct gatggaattt
    11701 cacgcgccaa aacagcctca gatgcgccag ccttttgtcc ccagaagtta atctgacgac
    11761 tgctagttac catggttgaa gcatcgtaga tggtcttaaa tgaataacca tcgcggttaa
    11821 ctacgtaaaa gacgcctgca tccccaatcg taatatagtc tgtcttgatt tcttccaaga
    11881 agtctaagaa aggcttgata cggtccatca tatcttggtg catgagagca ttgaccgcaa
    11941 cgagcaattc cttaccagca tcatgaacca acttagcgat ttcacgtaat tggtcataac
    12001 taaaggtcgt tggcagacga aggccaaaat ctttctcacc gacatagata cggtctacgc
    12061 cagcttcgag tagttgttca acttgttcaa tactttcagc agttgctgta atgacaatct
    12121 tttccataag aaaaattata ccacatttct ccaaaatcat ccatgctttg aaaatgaaaa
    12181 gggactttat tctttttgta acctttctgt aataattttc tgccgaaaaa atgataaaat
    12241 aggtatgtac tgttaaggag agaatcatgc ccgtaagaaa attacaatcc tatgaggtag
    12301 actatcaaga agaattaaac cagcagcttc ctcattacca agcttataca cctgaagcgc
    12361 aatctgatgc caatctcaag gaaatcctat tttttattaa tatcgctgtt ttttgtatct
    12421 gtattgctat ctttagtttt atctttttag cattaaaatt atcaactgct cttgcctttg
    12481 ccgcagcaat cggattcagc ttacttgttt taaaagttca acggtctatt atcaaacgaa
    12541 aacgtagaag ataaatccaa aatatcgccc cagttggagc gatattttta ttttttcttt
    12601 ttagatggtg tctgaatggc aatcttcact tcaaagattg ttcccttggg tttattatct
    12661 ttgacagtaa cagttccttt tagagcatct acaatttgct tggctaggga taatcctaaa
    12721 ccaaaaccac ctttttgccg ggttctagct ttgtctactc gataaaaacg gtcaaaaatt
    12781 ttctttttat cttctgtcga aataccgatt ccattatcag aaacaagtaa ataaagattg
    12841 cgatcggtcg ccgagataag aaaatcaatt tcaccatcct cctcagtata cttgacggca
    12901 ttatcgaaaa gaatggtcat cagttgtttc agaagaagct gatctgtgac aattgttcga
    12961 tggatacgat tttcaaaacg gaagacacga ttattttccg aagcaatcat ctcgtagttt
    13021 gtgaaagttg tattaaaaaa gctagttgga acttctgcaa gctccggctt aatcccatca
    13081 tctctccgag ctaagttcag caagcttgtc gttaaaaaac gcatatttcg gacttcttcc
    13141 aaactcgatg caatgctttc gctcacatcc ataatggtag cttctggctt acgaaaaagg
    13201 gtctctaagc gattttgcaa aactgcgagt ggagttcgta actcatgact ggcattttcc
    13261 acaaaagact gttgcttctg catactctca agcaggggcc taacactgac cctagctaga
    13321 tagagactgg caagtaaaga caaaatccag aaactagcca tcacgaccac aatcaattgc
    13381 tcatgctttt gactagcctg ctccaactga ctggtattaa tcaagacagc agcatacttg
    13441 atattggttg aaaccgaact aatattggtc tccatcaaaa tcacacgata gatttcttcc
    13501 tgcccatagc tattaaaaac ctgaatctgg tagatatgtc ctagttcttt cttttctaac
    13561 ttaatcttat ccaagcccaa aaatcgattt ccagaaagaa gttgagtaaa gtctttatca
    13621 aagagaatga cttccgtatt gaaactgaca ttaggtttta tttctacttt actagcgtcc
    13681 gccctagcat tttctaaatc tttaatctct tctgttgccc tatttatagc cagctgaata
    13741 actgcttgag gattttcact cagtccatga agcttatcgt ccaccgaagt ataaagactc
    13801 gaatgcatga cttgtaaaat aatcagagtc attgtagaaa aaatcagggt gaagacaccg
    13861 aagttgcgga taaaataact aaagtcatcc gcataccatg tttttttaag tttactgaac
    13921 atcttttaaa agatacccaa cactacgcaa ggtttgcaaa ttctctgcaa aagtggttcc
    13981 ctttaatttc ttacggactt ttgaaacata gacttcgaca accgaaatcg ttgtatcact
    14041 atcaaatccc catagacggt caaaaatctg cgtcttaggc aaaatcacat tttgattttg
    14101 aaggaaataa actagtaaat cgaactcttt ccccagcaat tcgacaggag tatcttcaac
    14161 tttaacggta ttggttgata aattaaccac gatattccca taagtcaagg tgttttcatt
    14221 aaacttccct gaacgtttga gaagggcctg aatccgcatt ttaagttctt ctaggtagaa
    14281 aggtttggtc agataatcat ccgctcccag ttcaaatcca tgtcccttgt catccaaact
    14341 ttccttggca gtcataatca gaactggtgt cgtaattccc ttttcacgca attcttttaa
    14401 gacttggaaa ccattttttt ctggcaacat caaatccagc aaaatcaagt catagacacc
    14461 actctcagct tcgtagagac cttcttctcc atcaaatacc tgcataacat ccgcaaaatc
    14521 gtctaaaaag tcaaatactg aatttgacag acctaggtca tcctcaacca ataagatttt
    14581 tatcatgaga aactcctcct tattaaaact attataccaa atttgcctta aaaaaaactc
    14641 aactctctgc attttacatg agatagctga gttttctttt tattttaggc ttatttatgc
    14701 atttccgtat tgaagaacaa ctgcttcgac tgcagctttt tcacggctaa tcaagtcaac
    14761 acgcgctgca atttccttga ttcccatacc gatgttacgg ctaagagcaa ggtcagaaag
    14821 ttgcggttca aagaactcct tgtattccgc caagcgttgc tgagtcttaa atacatgagc
    14881 aggaaggata acaaagctat caaagctcat atctcctcca agggctgcct taatccaagc
    14941 ccagttttca cgcgcccaag accaagctgt tttctgagtt gcttgatgag ctaggaattg
    15001 gtaataccaa gcagacaagt cctgtggttt gaccacaaat ttgtccttcc aagaagtaat
    15061 caagttttgg atattatccg catctgtact gtatgcaaga gctgctgtca actggcgttt
    15121 aaagacagca tctgttgcgt gagtataagt atcaagataa agtgctaaca agtctttagt
    15181 ctcatgatgt ttcatctcat taatcagaac ttgtgaacga atagctgctg ggagttctgc
    15241 aagattctcc ttgtgtgttg cgaagatttg gctagcgact tgacgagctt ctgcatcatt
    15301 tgagcgaatc atcatcgaaa cagccagctg acgaaccaat tcatcctcat ctgattctcc
    15361 gtctttagct tcaaaaccaa gacggtcata gttatgacga gccaatttag caaccagtcc
    15421 tttgaaggct gtttcagcat ccgttccttc atcaataaag cgctcaaggg ctgaaatcac
    15481 ttgagaaaca gctgaaacca ccagataaga ctcttcctta gcaagtttat caagaactgg
    15541 aagcaagtct gcataagaaa tgtgccctgc ctcagccaac aaacgacgtt cttgaacaat
    15601 ttgcagtttg cttgtgttat caagtgtctc tagctcagca agaacagctt ctaacaagtc
    15661 tccttgatag tcggtaatat agtgggcagt attttcagtg ttgagacgaa gagctccttc
    15721 attttcagca agaagagctg cgtagccagg gatttcgata ctttcagttt cgagtgtatc
    15781 aggcaagcct ttccagttgc tattgagggg caccacccag agacggttct tgtcttcgtt
    15841 ctcaccgatg aagaattgtt tttgtgaaat cttcaagaca tcattttcaa ctttgacagt
    15901 aagaactggg taaccaggct gttccaacca agaatccatg aaggctgcga catcacgtcc
    15961 tgacgcttga ccaagggcat cccaaaggtc actaccaatg gtgttgctgt attggtgttt
    16021 ttcaaagtag gcatgcaaac ctttagcaaa atcagcatct cctagccaac ggcgaagcat
    16081 gtgcatgaga cggcttcctt tggcatagac gatagcgccg tcaaagagtg tattgatttc
    16141 atctggatgt ttaacttcga cgtggacaga ctgaacgcca tcagtagcgt cacgttcaag
    16201 agcaagaggt actccacctg tttggaaatc ttcaaagata ttccagcttg gttcgatggt
    16261 atccacacag acgtattcca tcatattagc gaaactttca ttgagccaaa ggtcatccca
    16321 ccatttcata gtcacgaggt tcccaaacca ttggtgagcc aattcatggg ccacaacaag
    16381 ggcaacttgt tgacggctag caaatgtaga gttctcatcg acaaccaagt aaacttcacg
    16441 gtaggtcaca agaccccagt tttccatagc accagctgag aagtcaggaa gggcgatgtg
    16501 gagagattga ggaattggat acttaactcc atagtaatct tcgtaaaact cgatagagcg
    16561 aacagcgata tccagtgaga aatcaagatt tgaaagtgga tgtgctttgg ttgagtagac
    16621 acctaccagg gtaccatttt tagttttagc ggtcacccct tgcaaatcac cagcaaaaaa
    16681 ggccaacaag taagaagaca tgcgaggtgt tgtctcaaac ttccagatac ctgtttcctt
    16741 acggttttca acatcgattt ctggcatgtt tgacaaggcc aattcacctt ctgcttggtc
    16801 aaagcgaaga gagaggtcaa aagttgcttt ggcttcaggc tcatccacac atgggaaagc
    16861 ttcgcgcgca aaatggctct cgaactgagt agacaagacc tccttcttga ctccatcaac
    16921 tgtataataa gaagggtaaa tccctgtcat gttgtctgta attttaccag aaaaggcaag
    16981 aaccaattca acttgaccag cctcagccaa ttcgatatga agggcttcat tgtcatggtc
    17041 aactgtaaat ggacgagctt gacctgcaac ttctacagag gtgatttcca agtctttttg
    17101 gtggagggag atgcggtcac tctgtgcttg accagtgatg gtcactttcc cagaaaaagt
    17161 cttggtctca cgactcaaat ctaaaaataa atcataatgt tcaggaacaa attgcttaat
    17221 aaaatgttca actgcttgca tagttttctc ctattctaag tttaagagct gctgctcttc
    17281 ttcaaacaaa cttattatat catattttgc ttgaaaaaaa aggattggac agcgatttcc
    17341 aaaactttct tccttctaat agtctacagt gggtagacct tgcgaaattc ttctaaaaca
    17401 accttgcttt cagatgtaaa agtcagccct acttcaccca aacagtctgt gaaaaagtcc
    17461 tcatgaacct ggcgccaata ggcaagtgat ttgtctccct caccttcctt aaaggcatgt
    17521 tgcgcagaaa cttgattgaa gagttcaaca gaaacctttg taatttcgac aatgcagaca
    17581 gactgatttt gactatctaa aatgatatcg aaggtcccta cttggggaag tggttcgtct
    17641 tctagtacat agaggtcata ggctgatgct gttgctgtct tttctccttt aaacaccaaa
    17701 tccgctaaaa ggtctggttc aactccaaaa gcccaagcat cgatttcatc tccgatcaaa
    17761 ggattgattt gcttgtattt attccacatt tcttgcggta tcatgggtac tcctttgtaa
    17821 ttttttactt tcttctttta tgtgtttaag atgatctgga tggtcaatct ctaaatcaaa
    17881 aatctctgga atagaactgt agtggataat gcacttgata cccaactgat tcattttttg
    17941 tatgaaagaa gtattcagat agcctgctac agcaaaatca atcttgttct ttcttgcttt
    18001 atcctgcata tctcttagca tatctaacat tattggactt tccatatcat gccattgact
    18061 gtttctcata gtcgcaaaaa caaaggaagt caaatcattc attccaacta caatctttga
    18121 aatgcccgtt tccagtatac tagataagtc aaaatacgct gacggtaatt caatcatcgt
    18181 tccgactttc ccagtaaaac cctgctgacg caatactgta atagcttgtt ttaattggtc
    18241 gtcatcattg acaaaaggaa agataacaga tagattgggg ttggtttgat aaacttctgt
    18301 aacgacatgt gcttcagcct gaaattcatc caaacacgcc agtaaacgcc tggttcctct
    18361 atagccaaac aagggatgcc cttcgtcaaa aaactctcta gtccccacta aacaattggc
    18421 ttctgtattc gttaattcag aaaaacgata ccaaacttct tcatctgagt acagggagca
    18481 gatagtctct agataatctt ttacaaattg ctgacaactt gctaatatga tgttttgatt
    18541 aagctctctc aacaaatatt ccccacgaat catgccgacg tggtgaaata gttgaggata
    18601 aattttttca agaatttttt cgccactaag ggcaagttga tttctcatca ttcaccttcc
    18661 aattcatgta agaagtcttg tccagttctg gaaatcctaa taattcagac ttaaccttca
    18721 agactaatgg cgatgcattt tcttctgtaa tttcttgaat atccatccaa atatatccaa
    18781 gtgaatcatt cgcaccatca gacacagctt ccgaagtcgt aacttgaggt gcactctcat
    18841 tcatttcaac atcatacaag gccatgacat ggtgaaccat aaaatttttt aactcttctc
    18901 tgacgaaaac atcgtagatt cgaggattag agtagcttct aacagtaaat ctcgtctctt
    18961 ccataacttc tctagtcagc gtttccgtca gtccttcacc aagttgctga ctgcctccag
    19021 gtagatcata ccgatgttga taagggcctc tcgttttttc aatgcaaagt aactttccat
    19081 tttcaaagca aacacagtag accccaaagt gttttttgat ttccatccaa ctcctcctac
    19141 ttcaaagacc agccaccatc tattgtcaag atttgtcctt gcatggcgct cgcttttcca
    19201 cttgctaaaa aaagactaag ctctgctatt tcctctggct caatccagcg cttgattggg
    19261 gtttcactag ccacccagtc agccaaacca cctggttcaa aatccgcagc ggtcatagct
    19321 gtcttgactg ctcctggagc gataccaaag acctgaatcc cagcttcagc atagtctaga
    19381 gccaactgct tggtgaagcc agccaaggca tgcttggatg aagtataggc gtgaccacct
    19441 ccacctgcta ggctagaagc aatggaacac atattgatga tgattccctt tttattttcc
    19501 agcatttgtg tcaaataata ccgagtcaac tctactggaa taatgtagtt gatttcaaaa
    19561 atctcttgaa tgtcctgcgc cgtttgttcc aacagtggtt tgtaatcatc caaaactccg
    19621 gcagtattac acaaaacatc cacctgaggg caccagtcaa aaataggttc caagtccaag
    19681 gtcaaatctc tctgtaaaaa gtgaaaatca ccctctaaga gtggcttttc accttggtca
    19741 actccataaa cttgatagcc cttctctaaa aagaggcgag cttgagccaa tccgatccct
    19801 gaactcactc ctgtaatgag tacacgttta gtcatgcact tctacccaat ccgttgccaa
    19861 aacatcacaa gctgtcgggc tccacatgga aaaaccttct ccttctccag acacgttgat
    19921 taggaaataa ggtgtcactt caagtgcaag cccattttgc tcgatggtat caaagagttg
    19981 gacatagttt tccgcacctc cccaaccagt tcgtacatat tttttcttag cctttaagcc
    20041 aggtaaaatt tcttcaaatg tcatgttttt ctcctttaat gtcaataatt ctccccttca
    20101 ttataacaaa aaaaccgctt taaaacggct ttttgactgt gatttattca aacctgctac
    20161 tacttacggc aaattattcc ctgcagcaag ataaatttca taccattctt ttcttgttaa
    20221 gctaaagttt gccgctcggc taacttctct caagtgctta ggatttgttg tacctacgac
    20281 tgcctgcatt tttgctggat aacgcaatat ccaagaaatg gcaatagttg aagaggttac
    20341 tccatattta atagctaaac gatcaagtac ttgatttaaa gcttgaaatt tctcatttcc
    20401 aacaaagttc cctttaaaat acccgaattg caagacagac catgcttgaa tgaccacatc
    20461 gtgtaatttg caatattcaa aaatgctgcc atctcgcata gctgcttgac tatcttccat
    20521 attaacatga aaagctgatt caaatcctgg agtaaaagcc gcactcaatt gtagctgatt
    20581 aacagctaac ggctgcttga catctttttt aagcaactcc atcatcatag gattttgatt
    20641 agaaactcca aaatctcgaa ctttaccttg tttataaagg agatcaaagg cttctgctac
    20701 ttggtcagat tccatcaaag catctggtcg atgaaggagc aagctatcta gatgatcaat
    20761 cttcaatctt tgcaaaatac cgtctactga ttttataata tagtccttag aaaaatcaaa
    20821 ataggtaaat tcttcaatgc gaatgccaca tttggactga atccacatct tttctcttaa
    20881 atctggacga ttttttagga caagacctaa cagttcttca caacgaccac gaccataaat
    20941 atcagccaag tcgaaggcat tgattccaac agaaagtgct gtttctacaa gctcttcaac
    21001 ttcttttaca gacttatctt ttattctcat cattccgaga acaatttctg ataattcttt
    21061 gtcatcttga ccaagagtta tgtatctcat caaatttttc tcctttaatt tctaacattc
    21121 ttcccttcat tataacaaaa aaccgctttg caacggcttt ttgactatac ttcactccat
    21181 tttatcttct taaacccacg gaacaagaca aagattccaa taaagaggac agctaaagga
    21241 ataacttttg taaggaaaac atttgaaatt cccatccact cataataacg gagcagagaa
    21301 cccaccacaa gatgggcaat aatcatactg acaaatggac gaaagaccgc ttctttccaa
    21361 ttccaaatac cgataactag cgaaatcgta aagacagaca aactatccca gggagccgga
    21421 atataaaagg ctccttcttg tatgaagctt gccattccta catatcctaa aacaactaga
    21481 agaactatag tcccaacaac aatgtaagtg ccaattttca ttttaggaga atcttggact
    21541 aaacttcttc gtaaaattgt ggccacaagt ccaaatccaa tcagaaaaat aagaagttgc
    21601 cctaaaaatg tgagcaaatt gactgttaag agaggacctt tagaaaaatc acttagtagt
    21661 tgataataac gtaataccgc caggacaaga attggcgtca aaagggactc tttgatagaa
    21721 ctgcgaggtg ctcccttgag aatctctttc attatttttt taggattctt acctagataa
    21781 tcctctgcac tcatgccatc tcgttctgct tctgagaaat ctagcatcat caaatagatc
    21841 tgctctctga gatagtcttc atcatagaga aatccagcaa gattaaaact ttcccacaac
    21901 tcctcaaaat acttttgatt ctcctcagaa aactcatgta gcaaagcgct tgtttcttcg
    21961 taatacttca ttttcttcat ggtttaaccc ccattcttaa tcccttctac tttttgactc
    22021 aaatcgtccc attgttgcca aaagactgag acacgctctt ctccttcttt cattaatgaa
    22081 aaatacttcc gatctggacc atctggcgac gggcgcatgt cgcctcttat ccattgattt
    22141 ttttctaact tttgcaacaa aggataaata gttcctggaa cgatagtatc aaatccagcc
    22201 tctcgcaaag tctgaaccaa ctcataacca taccgctctt tttgaccaat catatccaag
    22261 acacaacctt caagaacacc ttttaatagc tgagtttctt tcatcacttc tcccttctaa
    22321 tctattttgt aatacctact agtaacttca cctatagtat atcacttcta cactagtttg
    22381 taaagcataa tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccctac
    22441 cgtatgtagg gttactgact tcgtcagttt catctacaac ctcaaaact
//
LOCUS       DAVHSH010000028        22143 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000028 DAVHSH010000000
VERSION     DAVHSH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.028"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(100..1119)
                     /gene="adhP"
                     /locus_tag="VVR08_001250"
     CDS             complement(100..1119)
                     /gene="adhP"
                     /locus_tag="VVR08_001250"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU6075165.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1458..2270)
                     /locus_tag="VVR08_001251"
     CDS             complement(1458..2270)
                     /locus_tag="VVR08_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6075166.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2460..3878
                     /locus_tag="VVR08_001252"
     CDS             2460..3878
                     /locus_tag="VVR08_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU6075167.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     NVHAMIWILDALFILNYISMAL"
     gene            3931..4638
                     /locus_tag="VVR08_001253"
     CDS             3931..4638
                     /locus_tag="VVR08_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075168.1"
                     /translation="MKEKNMWKELLNRAGWILLFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            4733..5713
                     /gene="folP"
                     /locus_tag="VVR08_001254"
     CDS             4733..5713
                     /gene="folP"
                     /locus_tag="VVR08_001254"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU6075169.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5715..7037
                     /locus_tag="VVR08_001255"
     CDS             5715..7037
                     /locus_tag="VVR08_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6075170.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            7018..7572
                     /gene="folE"
                     /locus_tag="VVR08_001256"
     CDS             7018..7572
                     /gene="folE"
                     /locus_tag="VVR08_001256"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU6075171.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7615..8427
                     /gene="folK"
                     /locus_tag="VVR08_001257"
     CDS             7615..8427
                     /gene="folK"
                     /locus_tag="VVR08_001257"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU6075172.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8472..8789)
                     /locus_tag="VVR08_001258"
     CDS             complement(8472..8789)
                     /locus_tag="VVR08_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU6075173.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9144..9590
                     /gene="rplM"
                     /locus_tag="VVR08_001259"
     CDS             9144..9590
                     /gene="rplM"
                     /locus_tag="VVR08_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU6075174.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9610..10002
                     /gene="rpsI"
                     /locus_tag="VVR08_001260"
     CDS             9610..10002
                     /gene="rpsI"
                     /locus_tag="VVR08_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU6075175.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10265..10690)
                     /locus_tag="VVR08_001261"
     CDS             complement(10265..10690)
                     /locus_tag="VVR08_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6075176.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKKAGMSLE
                     AISEALTHSDTVTTKTYVNTSNIVPLSAGQVAYQHLKNK"
     gene            10837..11013
                     /locus_tag="VVR08_001262"
     CDS             10837..11013
                     /locus_tag="VVR08_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075177.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            11414..13627
                     /locus_tag="VVR08_001263"
     CDS             11414..13627
                     /locus_tag="VVR08_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU6075178.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(13849..14325)
                     /locus_tag="VVR08_001264"
     CDS             complement(13849..14325)
                     /locus_tag="VVR08_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU6075179.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            14548..17751
                     /locus_tag="VVR08_001265"
     CDS             14548..17751
                     /locus_tag="VVR08_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU6075180.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WLHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENSETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            18104..18489
                     /gene="tnpA"
                     /locus_tag="VVR08_001266"
                     /pseudo
     CDS             18104..18489
                     /gene="tnpA"
                     /locus_tag="VVR08_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(18868..19497)
                     /locus_tag="VVR08_001267"
     CDS             complement(18868..19497)
                     /locus_tag="VVR08_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6075181.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(19507..20508)
                     /locus_tag="VVR08_001268"
     CDS             complement(19507..20508)
                     /locus_tag="VVR08_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6075182.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSSTSIENLLANAQDIIR"
     gene            complement(20539..21180)
                     /locus_tag="VVR08_001269"
     CDS             complement(20539..21180)
                     /locus_tag="VVR08_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU6075183.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLSK"
     gene            complement(21199..22014)
                     /locus_tag="VVR08_001270"
     CDS             complement(21199..22014)
                     /locus_tag="VVR08_001270"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU6075184.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6647 a         4038 c         4868 g         6590 t
ORIGIN      
        1 tatgttgagt ttttgaggag taatcttgaa ttcttattta aaatttaata taaaaaagtt
       61 ggaagaagct tccaactttt aaaataggtt tctattaaat tagtgggtga agtcgagtac
      121 catacgtcct tggatttggc ctttttccat ttcgtcgaaa atggcaacag catcttctac
      181 tggacgtttt tgaacaactg ggactaccag accttctgca ccaaattgga aggcttcttc
      241 taagtcttta cgagttccga caagagaacc gatgacttgg attccatcga ggactgtttt
      301 aacgatgctg agttccatca tttcagaagg aagaccaaca gcgacgacgc gaccaccagc
      361 acgaatggag tcaacagcct ggttgaaggc aactttagac acagcagtta cgacagctga
      421 atgagctcct ccatcagttt tttctttaat gagtccagct acatcttcaa cttcgaggcc
      481 gttaatcaca atgtcagcgc ctacttcttt tgcaagggta agtttgtcat tgttgatatc
      541 gactgcgata acatgagcat tgaatacttt tttagcgtat tgaacagcga ggttaccaag
      601 tccaccagca ccgtaaagaa caacccattg gcctggttca acttttgctt ctttgatagc
      661 tttataggtt gttactccag cacatgtgat agaagaagct tgggctggat caagtccgtc
      721 aggaactttg acagcatagt cagcagttac gatacattgt tcagccatac caccgtctac
      781 tgagtagcca gcatttttca ctgtacggca aagggtttcg cgaccagttg tacagtattc
      841 gcaagtgcca catccttcaa agaaccaagc aacgctgacg cggtcaccga ctttaaggct
      901 tttcacatct ggagcaatct ctttaacgat accgatacct tcgtgcccaa gaacacgtcc
      961 tgggacttga ccaaagtcac catgagcaac gtggaggtcg gtgtggcaaa cgccacagta
     1021 ttcaacttct acaagtgctt ccccagtttc aagtggacgg agtacttttt cttcaatagc
     1081 aacaccagtg ctttctggat ttacaacaac agctttcata gctatcctcc ttgatattga
     1141 ccgagaacag ggacaacggg actggattga ttttttgtca acagagtcga gtgtgacgag
     1201 ctctcttgta tttatatgtg aagtatatca caaaaggaag ccttttccaa ggttttggag
     1261 acaaaaagta gaacaatcga ttaactggtt gatgagactg tgaaaagagc acaaagacca
     1321 gcttgcaagc tggtcatact cttcgaaaat ctcttcaaac cacgtcagct tcatctacaa
     1381 cctcaaagca gtgctttgag caacctacgg ctagcttcct agtttgctct ttgattctca
     1441 ttgagtatca gtataggtta taagaataag tcttgtaggg ttttggcaac cccatcttgg
     1501 tcgttggtaa gggaaatttg ctcatctgca taagggagta gctctggatt ggcatttttc
     1561 atggcataac ccttcccagc aaaagcgagc atttcggtat cattgtgttc atctccaaag
     1621 gcaatcaaat cttttttgtc acgattcatt atcttgagca agtagtccaa agcaaaggcc
     1681 ttgttgacac cttttggggt acattcaagg atattgagcg gacctcccca ggtattgata
     1741 gaaagttgat gctggtagaa ggcgttcatt tcttttgcca aggcatattt gtcactggct
     1801 ctggtctgca agaggataca gttagggtcc ttggtcacca attcaggctg gaattgatct
     1861 tcaggctgga aagcttctac accaaatagt ttgggattgg caatttcttc attgggattt
     1921 gtaatgtaga attttttacg atattctcca gcgataaaat cggcttgaat gtcctctgaa
     1981 cgttgaacca tatctagcag atattttttg tctacagtca aacacttttc aaaatcccaa
     2041 acttggtctg gtaaatgagt aagggatccg ttgaagttaa tcataggagt gtctaagccc
     2101 agttcacggt aaaaatcttt tgacatacgg taagggcgac ctgtcgtaat aataacctga
     2161 tggccttttt cagcaacttt tttgatggtt cttttggtaa agtcagaaat ttgactgtct
     2221 gagttgagca gggttccatc caggtcaact gcaataattt ttttcgtcat atggaccttt
     2281 ctagtgtgtt ttcagataag atgtcttcta ttataacaga aagcaggcag aaaagcagat
     2341 tccaaacaaa aaatgaaatt ggattaattt cttaaacaaa tcaaacaaag acattgaaaa
     2401 agtgaatgat aaatgatata attctattat tgttcgtaaa aattaaaagg agattgatga
     2461 tggacaaatt atttaaacta aaagagaacg gtacagacgt tcgtacagag gttctcgctg
     2521 gtttaacaac tttctttgca atgagctata ttctctttgt aaacccacaa atactttcac
     2581 aaacaggaat gcctgctcag ggcgtcttcc tagcgacgat tattggtgca gtagcgggta
     2641 ccttgatgat ggctttttat gctaacttac cttatgccca agcaccaggt atgggactca
     2701 atgccttctt tacctttaca gttgtattcg ggcttggtta ttcttggcaa gaagccctag
     2761 ctatggtctt catctgtggg attatttcat tgattattac cttgacaaat gttcgtaaaa
     2821 tgatcattga atcgattccc aatgctcttc gctcagctat ttcagctggt atcggtgtct
     2881 tccttgccta tgtagggatt aagaatgctg gacttttgaa attcacgatt gatccaggca
     2941 actatactgt tgtaggagaa ggggctgaca aagctcaagc aacgattgca gcaaactctt
     3001 cagcagttcc aggattggtc agctttaata atccagctgt tttagtggct cttgcaggac
     3061 ttgccattac tatcttcttt gtcatcaaag ggattaaagg gggaattatt ctctctatct
     3121 tgacaacaac tgttcttgct attgcagttg gtttggttga tttgtctagt atcgattttg
     3181 ctaataacca tgttggtgca gcttttgaag atttgaagac aatctttggt gcagctcttg
     3241 gttcagaagg tttgggagct ttggtttcag atacagctcg cttgcctgaa actctgatgg
     3301 ccattcttgc cttctcattg acagatattt ttgacacaat tggtaccttg atcggtacag
     3361 gtgaaaaagt tggtattgta gcgacaaatg gtgaaaatca ccaatcagcc aaattggata
     3421 aggctcttta ctctgatttg attggaacga cagtcggtgc cattgcaggt acttcaaacg
     3481 taacgactta tgttgagtct gctgctggta tcggtgcagg tggacgtact ggtttgacag
     3541 ccttggttgt agctatctgt tttgcgattt caagcttctt tagcccactt ctagcgatcg
     3601 taccaacagc ggctacagct ccaatcttga ttatcgttgg gattatgatg cttggtagct
     3661 tgaaaaatat ccattgggat gatatgtctg aagcagttcc tgccttcttc acatctatct
     3721 ttatgggatt cagctactct atcactcaag ggattgcagt tggtttcttg acttacactt
     3781 tgactaagct tgtcaaaggt caagttaaaa atgttcatgc catgatttgg attttggatg
     3841 ccttgtttat ccttaactac atcagcatgg ccttataata gaatgaccca gggggatttc
     3901 cccccttttt taatacaaag gagataggtg atgaaagaga aaaatatgtg gaaagaattg
     3961 ttgaatcgtg caggctggat tttgctcttt ttacttgccg tccttttata tcaggttccc
     4021 ctagtggtta cctctatttt gactttaaaa gaagtagccc tgctacagtc agggctgata
     4081 gttactggcc tttcaattgt ggttctggct ctatttatta tgggagctcg taaaaccaag
     4141 ttagctagtt ttaatttttc tttttttaga gctaaagatt tggcacgttt gggcttgagt
     4201 tatttagtta ttgtcgggtc aaatatactt ggttctatct tgttgcaact gtcaaatgag
     4261 acgacaacag ctaaccagtc tcagattaac gatatggttc agaatagttc tctgatttct
     4321 agcttcttct tgctagcctt gcttgctcca atttgtgagg aaatcttgtg ccgtgggatt
     4381 gttcctaaaa agattttccg aggcaaggag aacttgggat ttgtagtcgg tacgattgtg
     4441 tttgctttat tgcatcaacc aagtaattta ccttctttat tgatttatgg aggtatgtcg
     4501 acagttctat cttggacggc ctacaagacc caacgtttgg aaatgtcgat cttgcttcac
     4561 atgattgtta atgggattgc tttctgtttg ttggctcttg tggtgattat gagtcggaca
     4621 ttaggaattt ctgtgtaaaa gtttttatgt aggaaccgac ctctttctac tagggaaaga
     4681 tgaatgcaat cgtgtccatc tttttctttt tatggtaaaa tagaaaaata atatgatgaa
     4741 aatccttgag ggagtgaccg atatgtcaag taaagccaat catgcaaaga cagttatttg
     4801 cggaattatc aatgtaaccc cagattcctt ttcggatggt ggtcaatttt ttgctcttga
     4861 gcaggcactc cagcaggctc gtaaattgat agcagaaggg gctagtatgc tagatatcgg
     4921 cggagaatcg actcggcctc ggccgggaag tagctatgtt gagatagaag aggaaatcca
     4981 gcgtgttgtt ccagtgatta aagcgattcg caaggaaagt gatgtcctca tctctattga
     5041 tactcggaag agtcaggtgg cagaggctgc tttggctgct ggtgccgatc tagtcaatga
     5101 tatcactggt ctcatgggtg atgaaaaaat ggcccatgtg gttgctaaag ctggagcgaa
     5161 agtggtcatc atgtttaacc cagttatggc tcgacctcag catcctagtt cgcttatctt
     5221 ccctcatttt ggctttggtc aaacctttac agaaaaagag ttagctgact ttgaaacatt
     5281 gccaatcgaa gacttgatgg tggctttctt tgaacgagca ctagcgagag cggcagaagc
     5341 tggtattgca ccagaaaata tcctgttgga tccaggaatt ggctttggtc tgaccaagaa
     5401 agaaaatctt ctccttttac gggacctgga taaactacat cagaagggct atccaatctt
     5461 tctcggagtg tcgcgcaagc gatttgtcat caatatcctt gaagaaagtg ggtttgaagt
     5521 caatcctgag acagagcttg gtttccgcaa tcgggacacg gcttcggctc atgtaaccag
     5581 tatcgctgca agacagggtg tagaagtggt gcgcgtgcat gacgtagcta gtcacaggat
     5641 ggcagttgaa attgcctctg ccattcgtct ggctgatgaa gcggaaaatt tagatttaaa
     5701 acaatataaa taagatgaaa gaaattgaaa acaatcagtg gattgctaac taccggacgg
     5761 atcaaccgca ttttggcttg gaacgaatgg tggaactgtt agctttgcgt ggcaatcccc
     5821 atctcaaact caaggtcctc catatcggag gaactaacgg caagggctcg actattgctt
     5881 ttttgaaaaa gatgctagaa aagctagggc tgagagttgg cgtgtttagc tcgccctatc
     5941 tcattcatta cacagaccag attagcatca atggggaatc gatctcagaa gcgaggctag
     6001 aagctctcat ggcagactat cagtctttgc tggagggaga agcggtcgcc aatttacagg
     6061 gcacaaccga gtttgagatt atcacagccc tggcctatga ctactttgcc tcagagcaag
     6121 tagatgtggc catcatggaa gttggcatgg gtggactttt ggatagtacc aatgtctgtc
     6181 agcccatttt gacaggaatt acaactattg gcttggatca tgtggcccta cttggtgaca
     6241 ccttggaggc catagcagag cagaaggcag gtattatcaa acaagggatg cccttggtaa
     6301 cagggcgtat tgctccagaa gccttggctg tgattgaccg cattgcggaa gggaaagatg
     6361 cgccgagact tgcctacggg acagattatc aggttcgtca tcaagaaagt gtggtgacag
     6421 gggaagtctt tgactataca agtgctgtca gacaaggtcg cttccagact agcctgcttg
     6481 gtttgtacca aatagagaat gctgggatgg ccatagcttt acttgatact ttttgtcaag
     6541 aagatggtcg agagctagca agcaatgact ttcttggtca agccttggaa gaaacaagtt
     6601 ggccagggcg tttggaaatc gtgtcaagag atcccttgat gattttggat ggagcccaca
     6661 atccccatgc tatcaaggcc ttgttggtaa ccttgcaaga acgttttgcg gattatcata
     6721 aggaaatcct cttcacttgt atcaaaacca aggccttgga ggatatgttg gacttgctgg
     6781 gagccatgcc agataccgag cttactctaa cacattttgc ggatagtcgg gcgacggatg
     6841 aaagcgtgct gaaagaggca gctaagtcta gaaatctcag ctaccaagat tggcatgatt
     6901 ttctagagca gaatttgaca gataaaaaag aagagaaaca aacagttagg attgtcacag
     6961 gttccttgta tttcttgagc caagtgaggg cctatctgat ggagaggaag aacgagaatg
     7021 gatacacaaa agattgaagc agctgtgaaa atgattatcg aggctgtagg agaggacgct
     7081 aatcgcgagg gcttgcagga aacacctgct cgtgtagccc gtatgtatca agagattttt
     7141 tcaggtcttg gtcaaacagc agaggaacat ttgtcaaaat cctttgaaat tattgacgat
     7201 aatatggtgg tagaaaagga tatctttttc cataccatgt gtgaacacca cttcttgcca
     7261 ttttatggta gagcgcacat tgcctacatt ccagatggtc gtgtggcagg cttgtctaag
     7321 ctagcccgta cggttgaagt ttattcgaaa aaaccacaaa ttcaagaacg tttgaatatc
     7381 gaagtggccg atgccttgat ggactatcta ggtgctaaag gagcctttgt tgtcattgag
     7441 gcggaacata tgtgtatgag tatgcgtggt gttagaaaac caggcactgc aaccttgacg
     7501 acagtagctc gtggtctatt tgaaacagat aaggacctcc gcgaccaagc ttatcgttta
     7561 atggggctat aaaaagaatc cgcttcaagc ggatttttct agaaaggaat cattatggat
     7621 caactgcaga ttaaggattt ggaaatgttt gcctatcatg gtctttttcc tagtgagaaa
     7681 gaattggggc agaaatttgt cgtttcagcc atcctatcct atgatatgac caaggcagct
     7741 acagacttgg atttaacagc ctctgtccat tacggagaat tgtgtcagca gtggacgact
     7801 tggtttcagg aaacgagtga ggatttgatt gaaacggtag cctataaact ggtggaacgt
     7861 acctttgagt cttatcctct tgtccaagaa atgaagttgg aactgaaaaa accttgggca
     7921 ccggtgcatt tgtcactaga tacttgctcg gtaaccattc atcgccgcaa gcaacgagcc
     7981 tttatcgccc taggaagcaa tatgggagat aagcaagcaa acttgaagca agccattgac
     8041 aaactgcgag ctcgtggcat ccatattctc aaagagtcca gtgtcttagc gacggagcct
     8101 tggggtggag tggagcagga tagctttgcc aatcaagtgg ttgaggtgga aacctggcta
     8161 ccagcacaag acttgttaga aaccttgtta gccattgagt cagagctggg acgggtgaga
     8221 gaagtgcatt ggggacctcg tttgattgat ttggacttgc tctttgtgga ggaccagatc
     8281 ctttatacag acgacctcat attgcctcat ccttacatag cggaacgcct ttttgtcctt
     8341 gagtccttac aggaaattgc gcctcatttt atccatccga tattaaaaca accgatccgc
     8401 aacttgtatg atgctttgaa aaaatagaaa aactctagtt ttcagttact tgcaactgaa
     8461 ggctagagtt tttaaaatag gtcattttct tctgggagga ggatagtttc tctaccgtcc
     8521 atgtctaaaa ccagtactct tgggggataa cgagggtcga aaggatggtt aaagtcaaaa
     8581 tcaatggctg tagggaggtg ttgacttgaa aagtggaagg taatctttcc ttggttatta
     8641 agcaattgaa actcgagttc ttcttccaat tcaaagacat tttttaagaa atggtcgata
     8701 atataccaaa aagagtcaat gatgtcatca ggcaagctgg taacaatgcc aaaactagca
     8761 gaccgcatgt gggtattggt aaaagccata tctctgtctc ctttcttttt ccttatcata
     8821 cagcaaatag gattaaaaat caagaaaagg tgattttttg aaaaggattt tagttacagg
     8881 gagaaatagg gaaaaattcc caaaaatcta ccgaagttaa taggtaactt cccaaattaa
     8941 cttgattata taactttcag ttattttgag aagttaccga aaaatatttt tcatatctat
     9001 tgacttttag gggtgaaatt tggtatgata gtaggcggta ttgtttaccc catttgaaag
     9061 gccccggaac cttccaaata cttttcgatg ggaaggaaca cccatcaccg taaacaaaaa
     9121 tcgaactata tataggagaa atcatgaaca aaacaacatt tatggctaaa ccaggccaag
     9181 ttgaacgtaa atggtacgta gttgacgcaa ctgatgtacc acttggacgt ctttctgcag
     9241 tagttgctag cgtacttcgc ggaaaaaaca aaccaacatt tacaccacac actgatacag
     9301 gtgacttcgt gattgttatc aatgctgaaa aagttaaatt gactggtaaa aaagcaactg
     9361 ataaaatcta ctacactcac tcaaaccacc caggtggatt gaaacaaatc tctgcaggtg
     9421 aacttcgttc taaaaatgca gtacgtttga ttgagaaatc agttaaaggt atgcttccac
     9481 acaatacact tggacgcgct caaggtatga agttgaaagt atttgttgga gctgagcaca
     9541 ctcatgctgc acaacaacca gaagttcttg acatttcagg acttatctaa ggaaaggaac
     9601 aaataaagta tgtcacaagc acaatatgca ggtactggac gtcgtaaaaa cgctgttgca
     9661 cgcgttcgcc ttgttccagg aactggtaaa atcactgtta acaaaaaaga tgttgaagag
     9721 tacatcccac acgctgacct tcgtcttgtc atcaaccaac cattcgcagt tacttcaact
     9781 gtaggttcat acgacgtttt cgttaacgtt gtaggtggtg gatacgctgg tcaatcagga
     9841 gctatccgtc acggtatcgc tcgtgccctt cttcaagtag acccagactt ccgcgattca
     9901 ttgaaacgcg caggacttct tacacgtgac tcacgtaaag ttgaacgtaa gaaaccaggt
     9961 cttaagaaag ctcgtaaagc atcacaattt agtaaacgtt aattcgaaag aattactata
    10021 cttatacaga gcacctttcg gggtgttctt tttttatact ttcttactaa attggtgcaa
    10081 ttgacacagt tgttgcgact ttagtcgctt acaaatgtgg ctgcaacctg acatggtcag
    10141 ttgcctcaaa acgttaatca atacgattat atcaacgttt caaagcactc aaaggtttgc
    10201 cctatgggtg cttttttcta tactttctaa aaaagtttgc cctaaaattt gccctaaaat
    10261 taccctactt atttttaaga tgttggtagg caacttgtcc agcagataat ggaactatgt
    10321 ttgaggtatt aacataagtt ttagttgtaa cggtatcgct atgagttaat gcttcagaaa
    10381 tggcttctaa gctcattcct gcttttttag cgagcgttgc tccggtatga cgtagtttgt
    10441 gtggcgtagc gtgtgtaagc tctgggtgtc gttttctgat agttttcatc ttattattga
    10501 gatagtcaga atgtaaaggt ttattgatat tgcctttggt atctatgtaa gtaaagatga
    10561 attgttctgg attactgatg ataccaaact ttgccagttc atatttttgt tgttttttcc
    10621 atgaagtcag aagttgaagt aagtcattag aaatagagaa aatgggaaat gtttccacaa
    10681 taaaacgcat attatcagat ggttaatgcg ttttatattt gggtttgagg tttataaaat
    10741 aggataagcg tgctgaaaac ttagatatga caaacaaaat aaaattttta aaagctacag
    10801 agaaacatgg tataatgtat ctaaaggagg tagcatatgt ccttagatat agataaagaa
    10861 aagatgacaa tcatgggaat agcttttgaa aaccgatccg tttttaagag tgtttggtat
    10921 gctttaagta caaatatgat tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta
    10981 cgagatgaag ctcttgctct ggggatgact taatgaagcg caactgttat gaatcttatg
    11041 actatgttga ttcggataat ttatataccg atccgggttc ttcagttcta agaaataagc
    11101 aggaaggaaa aaagcacgcg agcttgaata tcgtatgatt gctagtaaga gtttgaaatt
    11161 atttatcaat cctatcttag ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc
    11221 ttagaaaagt tgaaaagtga taactcttta ataaactctt ggtttgttaa aagatatttt
    11281 gtccactaca ttttttcaat tgactattat ttgtcataga tataacagat agaacattgc
    11341 attcagaata atgaaaaacg catcaaaaat ggtgcgttct gtttttatgc taccataaaa
    11401 ggagggaaac aaattgaaaa tttttaaggg agagttttat cgcatctctg tattaacaga
    11461 caagctagta aggttagaat actctaaaac tggcagtttt gaggatagaa ctacacaact
    11521 tatctataat agagattttg gccaagtttc gttagattat atcgagacat caaacgtact
    11581 agatattatg acggactatt ttcatctgca ctttaataaa ggagaattta acgccgaaaa
    11641 tttatttata gaattaaaag gaaattttgc cgtatatggt agtcgctggt attttggtga
    11701 atcgattgaa acgttaaaag gaacagctcg gactctggat aaggcagatg gagcaatccc
    11761 attagaagat ggaattatta gtcgaaatgg tatagcctta ttggatgatt ctcaaggatt
    11821 tatttgggat gaacagtctg gttatattga gagagaaaat caaattgacc tctatttctt
    11881 tgcctatggg catgattata gaggagcaat cagagacttt taccatttga ctggttcaac
    11941 acccttgtta ccaagatatg ctttagggaa ttggtggagt agatattggc cttatacgtc
    12001 ggatgaatac ttggatttaa tagacagatt tgaaacagag aaaattccat tatctatcgg
    12061 tgtgttagat atggattggc atataactga cattccagct cgttttggaa gtggctggac
    12121 aggatatagt tggaataaaa acttaatacc taatccagaa cagttattgc aacaacttca
    12181 tgatagaaag ttaaaactct ctttaaatgt ccatcctgct gatgggatac gggcttatga
    12241 agaagcttat cctcaagtcg ccaaacgatt agggttaaat gtagaactag aagaacctgc
    12301 catttttgat ttttttaatc cctcttttag ggaagcctac tttaaagatg ttcattatga
    12361 gctagaaaag cagggagtag atttttggtg gattgactgg caacaaggga ctcaaggcat
    12421 attggatcca ctatggcttt taaaccatta tcattatcag gatagttgta aaaatgcaga
    12481 aggtggtttg attttatcaa gatatgcagg tcctggtagc caccgctacc ctgttggttt
    12541 ttcaggggac actattatta gttggaattc cttaagattt caaccttatt ttacagcgac
    12601 agcatctaat atcggttata gttggtggag ccatgatatc ggtgggcaca tgctggggga
    12661 ttatgacgaa gagctgcaaa ctagatggct acagtttggt gtttttagtc cgatcactcg
    12721 attacatagt tctagaagtc cttttaatag taaagaacct tggttttttt cagaaacaac
    12781 atctaagatt atgaagaaat accttcgttt gaggcatcag atgattccat atctatacac
    12841 tatgaatgta aagacacacg aggaaggtgc cccattaatc agcccaatgt attatttcta
    12901 cccagagaat gatgagagct ataatgttcc aaaccaatac ttttttggaa cagaactaat
    12961 ggtggctccc attgtagaaa agatggactt ggcattccaa tctgcaaaag tggatgtatg
    13021 gttccctgaa ggtgaatggt atgacttctt ttcagagaaa aaatatacag gtggtgtgaa
    13081 gttgagtgtt tatagagaca tttcgactat acctgtgttt gcaaaaagtg gtgcgatcat
    13141 tcccttggtt ggttctgaga tagatatggg tgttgattta cctgaagttg tagattggta
    13201 tgtattccca ggcaaacaac attcttttga aatgcttgaa gatcaaaatg gtcaaagata
    13261 taaaacaaga ttatcaatcg attgggaaat ggggatggta gagttaacat tacaaggaga
    13321 ttctagtatc gttccaagca atagaaggca tagaattcat tttaaaggaa cgaatgtgtc
    13381 tataattgaa ttaccaaata agaatgatac agctagattt gaatgtaaag ataataaaac
    13441 aatatcttta aatgatgaag tttttagact actaaagaca gcttctcttc catatgaatt
    13501 aaaagataga ttgttaaatc aattcatcaa tgcgaaaaac tctcatgact taatgaatat
    13561 cttgcatcat caggataagg aattgagagg gcgtttgttg gaaatgatat ttactagcca
    13621 aaactaattg atataattag aaagtcattt gtttagtgta tatgaagatt ctgtatggta
    13681 ttcgttatca ctggtcacat tgaaaatgtg aaataagcac ctacaacata gactttacaa
    13741 cacttcatgt ttcatatcat ggggtgtttt tctatttaag tcaaagccaa tcaaaaaatc
    13801 tcactattca tcaggttaaa ggaaacctaa tcatagtgag attgtgaatt atagtagagt
    13861 ttgtatcgcc tcttcaattt gttttgggtc tgtttttgaa gaaaagcgtt caaagacttg
    13921 cccatctcga ccgatgagaa acttagcgaa attccattcg actcgttttc ctagtgggcc
    13981 ggatttctgg tcttttaacc agacatagag agggtctgct tccttaccgt tgaccttaat
    14041 cttggcaaaa cgtgggaagg tggtttgaaa atgtaggcta cagaaggcgt tgatttcctc
    14101 tgcgctgccg ggtgcttgtc ccataaactg attgcaaggg aaatccaata tttcaaagcc
    14161 ctgatcttga tagcgttcat agagttcttg aagtccctgg tactggggcg ttaaaccaca
    14221 tccagtagca gtgttgacaa tcaagagaac tttgccacga tagctatcca agggagttgc
    14281 ttggttgttt tggttcaaaa cggaaaaatc ataaagtgaa gtcatgaggg cctcttttct
    14341 ttttctacat tgtaacagtt tttacttttt tcgtcgagtc ggatggaaga tattgttgaa
    14401 gaataagccc tcaatatgat agaaaccgtt tacaaataac tttaaaaatg gtataattta
    14461 attaaaccgg tttacttagt tgctataaat ctctaatttg agatttagtt cctattgatt
    14521 ttacaatatg tttattggag tgtatacatg caaacaaaaa caaagaagct cattgtgagt
    14581 ttgtcttcac ttgttttatc aggattttta ttaaaccatt atatgacagt tggagcggaa
    14641 gaaacgacta cgaataccat tcagcaaagc cagaaggaag ttcagtatca gcaaagggat
    14701 acaaaaaatt tagttgaaaa tggtgatttt ggtcagacgg aggacggaag cagtccgtgg
    14761 acaggaagca aagctcaggg gtggtcagct tgggtagacc agaagaatag ttctgcagat
    14821 gcctcaactc gagtcattga ggctaaggat ggggctatca ctatctcaag ccctgagaaa
    14881 ttaagggcag cggttcaccg tatggttcct attgaagcta agaaaaagta taaactgcgt
    14941 ttcaagatta aaacagatca taaagtcggg attgccaaag ttcgtatcat tgaggaaagt
    15001 ggtaaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga ctggcagacc
    15061 attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga gttattctat
    15121 gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt agcagaccag
    15181 ctttctgagg attctcaaac agataaacag cttgaggaaa agattgattt accaattgga
    15241 aaaaaacatg ttttttctct tgcggactat acttataagg tagaaaatcc tgacgttgct
    15301 tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt cattgtcagt
    15361 aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt taaggatgca
    15421 tacacagccc gtttggatga ctggaatggc atcatcgctg ggaatcaata ctatgattct
    15481 aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc tgatagccta
    15541 tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc aaattataaa
    15601 atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa gcaagtgacc
    15661 aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag ggattccatg
    15721 gaatggctgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa ctggtgggat
    15781 tatgagatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa agaatacttc
    15841 tctgatgagg aaattaaaaa atatacagat gtaattgaaa aatttgtacc agaccccgaa
    15901 catttccgaa agacgactga taacccattt aaggctctag gtggaaactt agttgatatg
    15961 ggaagagtaa aagtaatagc tggtttactg cgtaaagatg atcaagaaat ttcttctacc
    16021 attcgctcga ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt ttatcaagat
    16081 ggatcctata tcgaccacac caatgttgcc tatacgggtg cttatgggaa tgttttgatt
    16141 gatggcctgt ctcaactgtt gccagtcatt caaaagacca agagtccaat cgataaagat
    16201 aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct ggtgaatgga
    16261 gaactgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga ggggcacgtg
    16321 gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga aggagaaacc
    16381 aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta ttatgatgtc
    16441 tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt aagtgatgca
    16501 ggagtcgcaa gtgttccaag accaagttac ctatctgcct ttaacaagat ggataaaaca
    16561 gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc cagtcgtacc
    16621 ttgaattacg aacacatgaa caaggaaaat aaacgtggtt ggtatacgag tgatgggatg
    16681 ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc aacagttaat
    16741 ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag cgatacaggt
    16801 aaagttttac cgtctgcttt cgttggaacg agcaaactag atgatgccaa tgcgacagca
    16861 accatggatt tcaccaactg gaatcaaaca ttgactgctc ataagagctg gtttatgcta
    16921 aaggataaga ttgccttttt aggaagcaat atccaaaaca cttcaacaga tactgctgca
    16981 actacaattg accagagaaa actggaatca agtaatccat ataaagtcta tgtcaatgat
    17041 aaagaagcct cccttacaga acaagaaaag gattatcctg aaacccaaag tgtcttttta
    17101 gaatcgttcg attcgaaaaa gaatattggt tactttttct ttaagaagag ttcaatcagt
    17161 atgagtaagg ctttgcaaaa gggagcctgg aaggatatca atgaaggaca gtcagacaag
    17221 gaagttgaaa atgaatttct tacgattagt caggctcata agcaaaatgg agattcttat
    17281 ggctatatgc taattcctaa cgtggatcgt gccaccttca atcaaatgat aaaagagtta
    17341 gaaagtagcc tcatcgaaaa tagcgaaacc cttcagtctg tttatgatgc taaacaagga
    17401 gtttggggca ttgtgaaata tgatgattct gtctctacta tttccaacca attccaagtt
    17461 ttgaaacgtg gagtctatac cattcgaaaa gaaggggatg aatataagat tgcctactat
    17521 aatcctgaaa cccaggaatc agctccagat caggaagtct ttaaaaagct agagcaagca
    17581 gctcagccac aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga aaagaaccat
    17641 tcggatcaaa agaatctccc tcagacagga gaaggtcagt caatcttggc aagtctaggg
    17701 ttcttgctac ttggggcatt ttatctattc cgtagaggaa agaacaacta atttgttcat
    17761 catctagatg aattacatga aactgtggaa aatagaaaaa atccgaagaa ggccaaatat
    17821 cttcggattt ttcttttaaa aaaggataag ttgatactta tcctttttta cttcattatt
    17881 atatgactat agcgttttga aactagaata gaacgttata actgctaaaa gatttctata
    17941 aattcatttg attttcctaa tcaatttgtt cgtatcctat ttcactccac tatataagtc
    18001 cgtctcgctc cgtgaggtgc gcgtcgaagg ttataccaaa aaaactccaa acgcgataca
    18061 ataaaggtgt tcaatccaat tgtaaagcga aaggagaaaa aatatggcac aaaagactca
    18121 tagtttatca tacacaaagt ggatgtgttc tatcatattg tgttcacccc taagtataga
    18181 cgaaaagtca tctataatca atatagaagt agtttaggcg aaatatttca tcgcttgtgt
    18241 agttataaag gtgttgaaat gatcgagggt cacttaatgc cagaccatgt acacatgtta
    18301 gtcagtattc cgtcgaggct aagtgtttca agttttatgg ggtatttaaa aggcaaaagt
    18361 gcactcatga tgtttgacaa acacgccaat ctcaagtaca agtttgggaa tcggaatttc
    18421 tgggcggaag gttattatgt aagtccagta gggcttaatg aagccacaat taagaaatat
    18481 agtcaagatt aaagaaatta tcgagtggat gatttcttca cgagtatgaa aatttgagaa
    18541 ctagtaaagt atgatatata gtaaaatgaa ataagaacag gacaaaatcg atcaggacag
    18601 tcaaatcgat ttttaacaat gttttagaag tagaggtata ctattccagt ttcaatctac
    18661 tatagcacta gataaattga gtgtaaaaga atatgaggat ccctttaggg atagtggtaa
    18721 gtaataccaa agtctcttaa agaggcaagt gacgagtcaa gagcaataag gcttgaacaa
    18781 cgtgaaagcc agcgtcttta ggcgctggct ggtaatttgg gcttatagct ctgggataaa
    18841 ccacccgttt gacgggtggt tatgatttta tctgagtgta atatactgtt gggcaatctc
    18901 gctgatgcgg tcaaagttgc cttgggaagc gagtttattg agttcgccac caattccaac
    18961 ggcatctgca ccagcagcga accattgagg gatgttgttt aggccgactc ctccggttac
    19021 cattacggaa acttgtggga tcggtgcctt aactgcagag atatatgctg gactgagagt
    19081 actacctggg aagagtttga tgatttcact accggcttca agtgcagtcg tgatctctgt
    19141 gagggtaata cagcctggaa tgtacggtgt gctgtagaga ttgcacattt tcgcagtttc
    19201 agcatggaaa gatggagaaa caacgtaatt tgctccagct agaatggcat ctctagcagt
    19261 tacggcatca agcacagtac ctgcaccgat acaaacactc tgatcgtcct gatacaagtc
    19321 tacaagttcc ttgatgattt gtcctgcata ctgattggta taggcgattt caatagcttt
    19381 gataccgccc ttgatacaag caatcgaggc ttgtagtcct tcttcctttg tatttcctcg
    19441 aatgacagcg acaattttct gtttttttag ttcaataatc gtatctgatt tggtcatgta
    19501 attctcctaa cgaatgatat cttgtgcatt tgccagtaaa ttttcaatac tagttgagga
    19561 agtggagaga tggtctcctg gaagagtgca tttgagagtt gcgctcgcaa ctgcaaagtc
    19621 aatggtagtt tttagggagg aatgatggag tagttggtaa agggcaccag atataaaggc
    19681 atccccgcta ccaattcgtt gatagactgc agtttttagt tggacagact cttcaaatcg
    19741 ttcttccaga gcataggctt gatagacatt tttgtcttgc tcatcactag atcggagggt
    19801 atggaaaatg gccttgaaac cataggcttc ttttaaaagt cgcatgcgat tttccacctc
    19861 ttctaggcta gcactgtctc ttggaaacat ctctagattt tggtcatcaa tcatgagagg
    19921 atcaataccg aagcaatagt cagtaaaacg tgcaaactta gaaaattcat acttggcttc
    19981 taggactgaa atcatctttg ttctcagatt gagatccatt gaaacgacaa ttcctcggcg
    20041 cttggcttct tccaagagta ggagaaggat cgcacggacc tcttgaccga tagctatggt
    20101 gattccacta aaatgaaaat ggctaatccc ctgaaagaga gaatccatat ctagcatgtt
    20161 tggccgaatc tggctgatac tcgtatgctt acgatcgtag aaaacttcac tttgacgaca
    20221 accaaagccg ttctccaaat agtagaggcc gattcgatcg ccaagccgac agattgaact
    20281 ggtatcgatt tggtgctgtt tcaagaatgt gagaaaacga tctccaatct cgttggcagg
    20341 gagtgcggta aagactttcg ttgagatacc cagggcttgc aaattacaag cgatgttaat
    20401 ttctgatccg ccaaaataag tcgaactggc aacatgatcg ccgatactgg tggcatctaa
    20461 tggtgagatt cgaattaatg gttcgccaaa cagtaatatt ttcgtcatcc attagttcct
    20521 ttctggttta gaatagcttt acttggataa tacttctttc aaataagcag cgacttcatc
    20581 atcttggcag ttttcaaaga agtattcttg gaagtatttg ccagagatgg tgtctttgag
    20641 gaagtcttgg tcgattgttt taaggatggt catcaaatca ttgtgggtga tttgtttcac
    20701 ctcgtttaag atacgagcgt tacgttgttc agggattaca cgttctcttg ggtagccacc
    20761 gcccatttct tcagcaaata agcgttcaaa catcaatttg agggtcagtt ctgcccccca
    20821 gccaaatcct ttggcataag ggatagacaa ggcgttacca ccattgattt gagaataaag
    20881 gtaagcgtca gttgggtcca ctgctagacc acagacaaca ccagggaagc tgtttaaagc
    20941 aagcatagcc cctacacccg taccacagcc ggtaacaaca aagtcaactg cctttgtatt
    21001 taaaaggatg gcagccatta gtccgttctg cacataagtt aattgacttt ctccttcttc
    21061 tccacgcata ccatagttaa ataattggta gtctttttta tctgtcgctt cttttagact
    21121 atcgtaaata atgtgattct tgctagcttg actattttca ttgattaatg cgattttcat
    21181 aagatcttct ttctattttt actcaggttg ttttccgatg taggctaaga taccgccatc
    21241 tacatatagg atgtggccat tgacaaaatt gctggcatca ctagcgagaa agacagcagg
    21301 gcccatcaaa tcttcaggat ttccccaacg tgcagcaggt gtttttgcaa tgatgaactg
    21361 gtcaaatggg tggcgagaac catcttcttg caactcacga agaggtgctg tttgaggagt
    21421 ggcaatataa cccggtccaa ttccgttaca ttggatattg gctccaccgt attcagacgc
    21481 aatgttgcgg gtcaacattt tcaagccccc tttagcagca gcataagcgc taactgtttc
    21541 acgtcccagt tcgctcatca tcgaacaaat attgataatc tttccatgcc ctttctttat
    21601 catagaagga ataactgcct ttgaaacgat aaatggtgcg tttaagtcaa tatcgatgac
    21661 cttacggaaa tcagcggcgc tcatttcgca cattggaact cggcggataa taccagcgtt
    21721 attaacgagg atgtcaatga caccaacctc ttgttcgatt tgcttgacca tggcttggat
    21781 accgtcctcg tctgtcacgt cacagacata tccatgggct tcgatgccaa cttcacgata
    21841 agcttcaatc cctttattga ccagatcttg attgatatcg ttaaagacaa tagtagcgcc
    21901 ggcttcagcg taggatttgg caatagcaaa tccaattcca taagaagcgc cagtgatgag
    21961 agcaattttt ccttttaaag aaaactgctc aattgagaat gatgtatttg tcatttgata
    22021 cttcctttca aatttgttaa gacttctcta taaccaaatt atattctagt aaaccggttt
    22081 tgtcaataaa taaatatttt tatttataaa aagatttatt ttcctaaaaa aacggaagat
    22141 ttt
//
LOCUS       DAVHSH010000029        21220 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000029 DAVHSH010000000
VERSION     DAVHSH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.029"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..259
                     /locus_tag="VVR08_001271"
     CDS             <1..259
                     /locus_tag="VVR08_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075185.1"
                     /translation="WFQKFFLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLP
                     PYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            complement(252..419)
                     /locus_tag="VVR08_001272"
     CDS             complement(252..419)
                     /locus_tag="VVR08_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU6075186.1"
                     /translation="MKKRILSAGLTFTSALLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(584..2191)
                     /locus_tag="VVR08_001273"
     CDS             complement(584..2191)
                     /locus_tag="VVR08_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU6075187.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2344..3828
                     /locus_tag="VVR08_001274"
     CDS             2344..3828
                     /locus_tag="VVR08_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU6075188.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3923..4405
                     /locus_tag="VVR08_001275"
     CDS             3923..4405
                     /locus_tag="VVR08_001275"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU6075189.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4472..4807)
                     /locus_tag="VVR08_001276"
                     /pseudo
     CDS             complement(4472..4807)
                     /locus_tag="VVR08_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(5259..7364)
                     /locus_tag="VVR08_001277"
     CDS             complement(5259..7364)
                     /locus_tag="VVR08_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6075190.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEDLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGCLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(7973..8953)
                     /locus_tag="VVR08_001278"
     CDS             complement(7973..8953)
                     /locus_tag="VVR08_001278"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU6075191.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKIFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8955..11207)
                     /gene="pbpX"
                     /locus_tag="VVR08_001279"
     CDS             complement(8955..11207)
                     /gene="pbpX"
                     /locus_tag="VVR08_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU6075192.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     DYKSATGKILYVEKTQFNKVAEIFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMTLAAAIDNNTFPGGEVFNSSELKIADVTIRDWDVNEGLTGGRMMTFSQGF
                     ALSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEVVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(11211..11528)
                     /gene="ftsL"
                     /locus_tag="VVR08_001280"
     CDS             complement(11211..11528)
                     /gene="ftsL"
                     /locus_tag="VVR08_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU6075193.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(11540..12490)
                     /gene="rsmH"
                     /locus_tag="VVR08_001281"
     CDS             complement(11540..12490)
                     /gene="rsmH"
                     /locus_tag="VVR08_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU6075194.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQACLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            12656..12850
                     /locus_tag="VVR08_001282"
     CDS             12656..12850
                     /locus_tag="VVR08_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075195.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            12866..13408
                     /locus_tag="VVR08_001283"
     CDS             12866..13408
                     /locus_tag="VVR08_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU6075196.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            13419..13661
                     /locus_tag="VVR08_001284"
     CDS             13419..13661
                     /locus_tag="VVR08_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075197.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            13672..14007
                     /locus_tag="VVR08_001285"
     CDS             13672..14007
                     /locus_tag="VVR08_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075198.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(14117..15118)
                     /locus_tag="VVR08_001286"
     CDS             complement(14117..15118)
                     /locus_tag="VVR08_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6075199.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(15178..17079)
                     /locus_tag="VVR08_001287"
     CDS             complement(15178..17079)
                     /locus_tag="VVR08_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU6075200.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(17101..17394)
                     /gene="yajC"
                     /locus_tag="VVR08_001288"
     CDS             complement(17101..17394)
                     /gene="yajC"
                     /locus_tag="VVR08_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6075201.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLISLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(17394..18212)
                     /locus_tag="VVR08_001289"
     CDS             complement(17394..18212)
                     /locus_tag="VVR08_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6075202.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(18199..18978)
                     /locus_tag="VVR08_001290"
     CDS             complement(18199..18978)
                     /locus_tag="VVR08_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6075203.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(18993..19484)
                     /locus_tag="VVR08_001291"
     CDS             complement(18993..19484)
                     /locus_tag="VVR08_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6075204.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(19495..20685)
                     /locus_tag="VVR08_001292"
     CDS             complement(19495..20685)
                     /locus_tag="VVR08_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU6075205.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(20697..21131)
                     /locus_tag="VVR08_001293"
     CDS             complement(20697..21131)
                     /locus_tag="VVR08_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6075206.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT         6155 a         4840 c         3806 g         6419 t
ORIGIN      
        1 atggtttcag aagtttttct taccaacatt aaccacacca tcggttatta ttatggataa
       61 tgcaagattc catagaatgg gtaagttaga actcttgtgt gaagagtttg ggcataaact
      121 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      181 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttatgagg ctcttttgtc
      241 ctgttcttgt ttcaattgac tatattatca gcgtaatagt ctaatagata gttaaatgta
      301 gttggatttc cactaaaggt tgatgagtaa gtttttgtat ctgaacctga ttggccgcaa
      361 gcagctaaaa gcaaagcaga tgtaaaagtc aggcctgcac taaggatacg cttctttatg
      421 ttcgtcttct ttctccttaa tagtgggaat ttgtaaagtt aattgaattt cgagaatgaa
      481 ggtttataaa ccttggttat aaaaaacaaa ggatttctgc cttttataca gtcctccctt
      541 gtttttatac gatttcaatt ttaaattttt ctgcaaaaaa tatttatagt aattccacac
      601 agaaagcatc ccatggaact aagatttgtt tttcaaagac ttcttgagct agggtgtttt
      661 caatcaagac agatttgact tttccttcta ctgtcaagtc ttgctcttca ttggacaagt
      721 tagccacaac taggaagcga cggtcgccat ccttacgtat ataagcaaag accttatcag
      781 ccgtatcaag caattcaaag tcagctcgaa ttagccagct attctccttg cgaatttgga
      841 ccagtttctg ataggtatag aaaatagaat ctggatttgc cagcgcttct tggacattga
      901 tcatctcgta atttggatta accgccaacc aaggttgacc tgttgagaaa ccagcgtttt
      961 tgctctcgtc ccattgcata ggggtacggg cattgtcacg tccaataaca cggatactgt
     1021 ccatgatttc ttcaatcgga acaccttttt caagagcctc acgcgcatag ttgagggatt
     1081 caatatcttc tacttgatcc agtgtttcaa acggatagtt ggtcatccca atctcctcac
     1141 cttggtagat ataaggagtt cctctcatga gatgaagtaa gattgcaaag gctttggcag
     1201 atttttcgcg gtattcttgg tcatttcccc agattgagac aatacgaggg aggtcatggt
     1261 tgttccagaa gagggaattc cagccgtcct caactcctaa ctctgtctgc catttgttga
     1321 agatttcttt taacttagcg atattcagct ctttttgata gtgccattta ggctgacctt
     1381 cctgatactg aagaccgata tgttcaaact ggaagaccat agacaattct tgcccctttg
     1441 gatcagagta gagcttggca atctctggcg ttgctcccca agtctcccct actgtcaaga
     1501 gatccttatc tccaaaggtc gcctgattca tttccttgag atagggatgg agcataggac
     1561 cattattgac taccttctcg tcaggaattt tgccaatcat gtcaataaca tccatacgga
     1621 aaccaccaat acctttatca atccagaagt tcatcatctc ataaattttc tggcgaagtt
     1681 tttcattttc ccagttgaga tccggctgtt tcttgctgaa aaagtggaga tagtattgac
     1741 ctgacttttc atcgtattcc caagcagacc cactaaagat agaatctagg tcattgggtt
     1801 catcgcgcca gatatagtag tctcgctcag ggctgtcagg attttcacag gcctctacaa
     1861 accaggcatg ctcatccgag gtatgattga ccaccaagtc catgatgata cggatatcac
     1921 gcttcttagc ttctgcaatc agttgatcca tatcctccat ggttccaaaa atcgttgcaa
     1981 tcgcttgata atcagcaata tcgtagccat tatcatccat agggctgtca taaacgggag
     2041 aaagccaaat tgctgtgatt cctagcttgg ctagatagtc caacttactg gtaattcctg
     2101 gcaaatcacc aactccatct ccattactat ccataaaact ctttggatag acttgataga
     2161 ctacggcatt gtgccaccat ttttcttgca tcttcttacc tcattatttt cataatctat
     2221 agtctatgat agcacttttt aaaattttgt gcaagcgttt gcttaatctt tttaatttct
     2281 tttttagctc cgtagtttcc taacttccaa ttttttatta taatagagtc cagaggtaaa
     2341 aaaatgaaaa aacaagcttt tagttctgaa caatatttaa atctacaacg cgaccacatc
     2401 ttagagcgca ttaaccaatt tgacggcaag ctttacctag agtttggtgg caaaatgtta
     2461 gaagatttcc acgctgctcg tgtccttcct ggttatgaac ctgacaacaa aatcaagctc
     2521 ttgcaagaat tgaaagagca ggttgaggtt gtgattgcca ttaatgctag caacattgaa
     2581 cattccaaag cacgtggcga cctaggcatt tcttatgacc aagaagttct tcgtttgatt
     2641 gacaaattca atgaattagg gatttttgtt ggttccgttg tcattacaca atacgctggg
     2701 caacccgctg cagatgcctt ccgcaaccaa cttgagaaaa acggaattga ttcttatctt
     2761 cattatccaa tcaaaggata tccgacggat atggatcaca tcatttcccc agaaggcatg
     2821 ggcaaaaacg actacatcaa aaccagtcgc aacttgattg tcgtaaccgc tcctggaccc
     2881 ggttctggaa aattggcaac gtgtatgtcc aatatgtacc acgaccaaat caatggcatc
     2941 aagtctggct acgctaaatt tgaaaccttc cctgtttgga atcttcccct tcatcatcca
     3001 gttaacttgg cttatgaagc tgccacagct gaccttgatg atgtcaacat gattgacccc
     3061 ttccatcttc aaacctatgg agaaaccact gtcaactaca accgtgatat cgaaatcttc
     3121 ccagtgctca agcgcatgtt ggaacgtatt ctcggaaaat caccatacgc ttcaccgaca
     3181 gatatgggtg tcaacatggt tggtttcgct attacagatg acgaggctgc tgtcgaagct
     3241 tctaaacaag aaatcatccg ccgttactat caaacagttc ttgacttcaa agctgaaaaa
     3301 gttggcgaag ctgccgtcaa gaaaattgag ttgctcatga acgacctcgg tatcacacct
     3361 gcagaccgta aggttgctgt cgttgcgcgc caaaaagcag aagaaactgg tggaccagcc
     3421 ctagcctttg aattgccaaa tggggaaatc gtcactggta agaactcaga actctttggt
     3481 cctacagccg ctgccttgat caacgccatc aaaaaatcag ctgacatcgc taaagaagta
     3541 aaactaatcg agcctgaagt tgttaagcca atccaaggtc ttaaaatcga tcatctcggt
     3601 agccgcaatc cacgccttca ttcaaatgaa atcctgattg cacttgctat cacagctaca
     3661 gaaaatcctg atgctgcccg cgctatggaa gaactcggca acctcaaagg aagcgaagcc
     3721 cactcaacca tcatcttgac tgatgaagac aagaatgtcc ttcgtaaact gggtatcaac
     3781 gtaacctttg acccatacta ccaatacgac cgcttatatc gtaagtaaag atttcaacct
     3841 ctccagcctc ggagaggttt tctctctgtc tcaggagcaa cctttatgat ataatgagag
     3901 aagaaaactg aaaggattta ccatgtcaaa agaagttatt gtcgaaagtt ttgaacttga
     3961 ccacaccatt gtcaaagcac cctatgttcg cttgattggg gaagaaacag gacccaaagg
     4021 agacatcatc tccaattatg atattcgctt ggtgcaacca aacgaagact ctatccctac
     4081 tgccggcctt cacactatcg agcacctctt agccaaactc atccgtaccc gcattgacgg
     4141 catgattgac tgttcaccat ttggttgccg cacaggcttc cacatgatta tgtggggacg
     4201 tcacaccagt gctaaaatcg cagctgttat caaggattcg ctcaaggaaa tcgctgaaac
     4261 tactacttgg gaagatgtcc cagggacaac catcgaatct tgcggaaact acaaggacca
     4321 cagcctcttc tctgctaaag aatgggcaaa actcatcttg gaacaaggga tttcagatga
     4381 tgcctttgaa cgtcatgtga tttaaaatcg agtaggggat aatctctagc ccctctcaca
     4441 ccaccgtacg taccattcgg catacggcgg ttcaactaac ttttaacgca tgtcgttcaa
     4501 ggtaataatc caaacacgaa accagtccgc gtttttcaag gactggtttt gatatagcac
     4561 gtttaagtac cgacttctga gctactaatt gatagtggtc gccccagcca gataccttat
     4621 ctgctatcca tttaggaacc cctaacttaa gcaatcccca taatcgtctc gattttttct
     4681 tccattgctt ccagataatc actcgtaggc gagtatgcaa gcgctcatct atgctagtga
     4741 ctatactttt catatttccc aatgagaaat agtttatcca tcctcgaaca gacaaattca
     4801 gttgctctcg tgatttacgc atataggcta cgactacctt tttgaacttt agagtttgag
     4861 gccccttatc cgctatatac gccttattat cacgttccta ttcgtagagc cacgatttcg
     4921 ctatcccttc ctctgacgat tcttatttcc agcgtcagac ttaaaacggt ctatccccag
     4981 accgttttaa tccgctacct cacgatagtc aggcttggga atcgctattg ggttcaccgg
     5041 taacaggtgc ccaccgagga cttacacctc agatatatag taaaatgaaa taagaacagg
     5101 acaaatcgat cgggacagtc aaatcgattt ctaaaaatgt tttagaagta gatgtgtact
     5161 attctagttt caacctacta cacgacatgc ccgtcgtacc tagaaaggaa ccagtttttt
     5221 tcagctggct ccttcttttt tatcctcaaa attctgtctt aggctttctc acgaataacc
     5281 aaaacgccat cttccatatc tgcttccaga tgtttagcat ctaaatgatc caagtggaag
     5341 tctgtcacct tatcacgaat ttcttgttca accactcgac ggagaggacg aacccccatg
     5401 acttcgtcgt aaccttcttc tgtgatataa tctttagccg cttgactgac taccaagtca
     5461 atgtctttct tagccaaggt ttggttaact tcagccaaca tcaaatctac aatcttagaa
     5521 aggtcttcct tagtcaagtg tgagaactcg atgactgcat taaagcggtt gaggaattct
     5581 ggacggaaga agggtttcaa acggtccatc aattctggtt tatccgcatc ttctgtcaag
     5641 ttggcttcat agccaaatcc agcatttgag gtcgcaataa tgacagtgtt cttgaagttt
     5701 actgtatttc cttgaccatc tgtcaaacaa ccatcatcta gaacttggag gagaagggta
     5761 ataacttgag ggtcagcctt ttcaatttca tccaagagaa tgatagagta tggattgcga
     5821 cgaacacgtt ctgttaaggt attgctattg tcatcataac ccacatagcc tgctgttgta
     5881 ccaattagct tagaaacagc tgtgcggtca ctgtattcag acatatccaa acggataatc
     5941 gcatcctggg ttccaaacat atcgagtgcc aattgcttag caagctccgt cttaccaacc
     6001 ccagtagacc ctacaaagag gaagctgccg attgggcgat ttccttcatc aaaaccagca
     6061 cggttacgac ggatagcacg agctacagct tctacggcct tatcttgacc aatcaccttg
     6121 tcttgcaagc gatgagccat atctttcaaa cgttcgatat ctgaagctcc catttgcgat
     6181 actgggatac ctgtcattcg ttccacagat tcagccacat cgttgacact tgcagtcact
     6241 ttcatatctt ctgtgtggtt ttcgattttc ctttccaatt ctgcaatgcg cgttttatag
     6301 tttagagctg cttcaaaatc ttctgcttca actgcttttt cttgcttgtc tttttccgtt
     6361 tcgatttctc gttcaacagc atgcacatct gttactggat gttgagccgc caagtgagca
     6421 gccgttacat cgacaaggtc aatagcctta tctggcaagc tacgttgagg aatgtattga
     6481 acagaataat ccaccgctgc tttcaagact tcgtctggca agatgacatt gtggtgttgt
     6541 tgatagaggt cacgaatgcc ttgaagaatt ttaaaagtat tctctgctga aggagcattg
     6601 accttcactt cgttgaaacg acgagcaaga gcagcattct tcaagatggt gttacggtat
     6661 tcgtcttgag ttgttgcccc aatcactgtc aattctccac gagagagagc tggcttgaga
     6721 atatccgcaa gtcctttaga accactgtct ccaccagtgc taccagcacc aagaatttgg
     6781 tgaatttcat caaagaagag gataatattc cctgcttctt tcacttcatt gactaagttt
     6841 tggacatttt cttcaaagct accacggtat tgagtaccag cctcaagacc tgagatatca
     6901 atagaaataa tttccttgtt cttgatagca gcaggaacat ctccgttcac aatggcttgc
     6961 gctagatctt cgacaactgc tgtcttacca acacctgcat ctccgaccaa aacaggattg
     7021 ttcttggtgc ggcgtgagag gatttcagat gtttcttgaa tttccttgtt tcgtccgata
     7081 acaggatcca acttgccctc acgcgcttct gctgtcaagt ttcgacctag ttttgcaagg
     7141 acaccgtctt gtttcatacc tgatgcctgt tgtggcattt gcacatcagt ttctgcattt
     7201 cctggtaatt gaccagtcgc acgatagtga gcaaattcct caggtgtgac ttcgcgtcca
     7261 ttaattaagt aacggcgatt ttcagaactg tatcctcgca taccacccat caattggtta
     7321 aataaatcat ccatgttatt aaaattatta aagttgttat tcatattctt tacctctttt
     7381 tgtttacaaa gttatgatta ctgatattga ctatctttga ccattgtttt aaaaaattta
     7441 gactagctaa accgctaccc tacgtactat ttctggtttt tctttttcaa gcaggagtag
     7501 actatcttta cttctgaaaa tttctagatg aaacatagac ccacctcttt ctattttact
     7561 ttaaataagt gttctagtaa ggctttcatt taccttacgt tcataatata ctacattggt
     7621 cagaaaaggt caagagtttt gactttaact gaccaatatt tttttacact cttcgaaaac
     7681 ctcttcaaac cacatcatct tctccttatc tacaacctca aaaccgtgtt ttgagctgac
     7741 ttcgtcagtt ctatcaacca tctcaaaact gtatattaaa atgaaataag aacagtacaa
     7801 atcaatcagg acagtcaaat cgatttctaa caatatttta gaagtagagg tgtactattc
     7861 tagtttcaaa ttactatgtt ttgagcagcc taaagttagc tttctagatt gttctttgat
     7921 tttcattgtg tatttaaaca caaaaacacc ctgaaacatc agggtgccat tcttacatca
     7981 aatataaaat tgctagggtc aggagacttg ctagaagccc aactccccaa aagaagaagt
     8041 caaccttcca ctcgctccaa ggatttcctt taccagacaa tcccccaagc tcaaaatggt
     8101 gatgtacagg cgtcatacgg aaaatacgtt taccacctgt cagtttgaaa taactgactt
     8161 gcatcataac agaagttgtt tcaaaaacat acacaattcc gataatcaag agagtccatt
     8221 cttggtggag agccatagag atagctgcca gcattccacc taaagccaaa cttcccacat
     8281 cacccataaa tatcttagca ggcttatggt taaagatgaa gaaactgagc aaaccaccaa
     8341 tcatggccag aatcactaga agaatatcca tctgaccttg cacataggca ataactccat
     8401 aggcagacaa actaatcaca acggaaatac tagctaaacc gtcaacaccg tctgtcaagt
     8461 ttactgcgtt tgaaaaaccg actagccaga aaagagcgaa gacaatatag aaaatcccta
     8521 gatgcacttg ataaccaaag acagaaagca tatcgccacc gcgctcatag aaaagataga
     8581 agataactcc acctagaagc tgaagagcta atttttgctt aggattaagc ccctcattga
     8641 ttttacgaaa gaccttgaga aagtcatcta aaaatccgac caagccatac aagactaata
     8701 tgaacaaaat cattcccaca ttattgctga attggctact aaatagggcg aaaaagaaag
     8761 caaccaaaac agaagtaatc aagaaaacca aacctcccat tgtaggagtc ccagcttttg
     8821 cctgatgctg tttgacatcc tcatgcatct gctggcctgt aatttgcgcc tttctataaa
     8881 attggataaa ggccggaatt cctactaaag ttagtaaaaa tgtcacaatt ccagcactga
     8941 tggaaataaa catattagtc tcctaaagtt aatgtaattt ttttaatgtc cttgatagct
     9001 gtgttagcac gaacatcttg cttctgcaca gtagagcccg aaccttgaaa ttcaagttct
     9061 atattgagcc acttagcaag ggtctcagca gtctcctttg tccaaccata catatctgga
     9121 acttcctctg ctttatcaga taagataagg acttgctgat tcggggcaag attcttccct
     9181 tcttcagcag aactgttttt aatcttcgtt cctgttccca caacgatggg ttgtacaaga
     9241 ttgcgacgca attcttctgc taaatcacca ggtgaaatat ccttgacact aggcatagga
     9301 taaggacttt gttgacttac ttgctccaaa gctttagctg ttgtttgaag attgagagag
     9361 tctttcatgg ctgaagcccg ctccaagata ggattggcaa attctcccaa ctggatacct
     9421 gaataatgct caggctgttg aaccgttaca tacaagataa aatcaggatt ttcagcagga
     9481 ttcatagtca caactgagaa aatataattg gtagaaccaa ccaagtatcc tccatttttc
     9541 tcatcagcga tttgagccgt accggattta actgctacat tttgtccagg aactgttata
     9601 attggctttc ctgtgtagtg gttatacatg gttccataaa ccggatccgt ccctaccaaa
     9661 accatgttag tccgagttag actagctgca tctttggaaa caggatttcc cacaacttct
     9721 ttttgagatt tccgagcagt ttgatcattt ggatcataaa tggcactaat aaatttaggt
     9781 tccagcatga caccgtcatt agcaatagct gtaaaggcac gaatcatttg cgtctgggtc
     9841 actgaaatcc cttgcccaaa tgagctttgc gcaatgttaa cgatattatc cgcaggaagc
     9901 tgaccagcat actcatccgt caaaccgaaa cgggtcggaa caccaaattt aaaacgatta
     9961 agataatcaa gccaggtagc atctcccatc ttttgctcaa ggagggtcat cccaacgtta
    10021 cttgagagtg caaaaccttg agaaaaagtc atcattctgc caccagtcaa tccttcattg
    10081 acgtcccaat ctcgaatcgt gacatctgca atttttaact cactactatt gaagacttct
    10141 cctcctggga aagtattatt atcaatagca gcagcgagcg tcatgacctt catggttgac
    10201 cctggctcat agttactttg atagagaata tcccgccaaa caaagtcctc tgtaatgcct
    10261 tcttttgtat ctgcatcaaa ggtcggtcgt tgcgttgttg ccagaatttc ccctgtttta
    10321 gcactgacca aagtcgctgt catgtacttt ccttttacct tctcttgaaa agcatccatc
    10381 tgggtttcca taaaggactg gagggggctg gaaatggttg tataaacatc cttaccgtcc
    10441 atcgttcgtt gggaaacttg ttctgttccg ggtacaatat tacccagacg atccttttca
    10501 taggtaataa tgccgtctgt ccctgcaaga atactgttca aggaactctc cattccagag
    10561 gttcccagca agctcttgct tccatcttca ttttcatgga gctgagctag gccgataaaa
    10621 ctagaagcaa attgtccgtt tgggtaacta cgattgggac tggttgtaaa atcaatcccc
    10681 ttgacctctg cagcttccaa ttcttttttg atagacatca tattggcata ggtaatccca
    10741 tttccctttg ctccaaagga aacttgcttg agattaggtt gcgagagttg ctctcttaca
    10801 taagattctt ccatgtccag atacttatga aagatctctg caaccttgtt aaattgtgtt
    10861 ttttctacgt aaagaatctt acccgttgct gacttatagt cctcatcaat gaccgcatag
    10921 acattatagg aggttgcatc ctcagcaatc gggactccat ttcggtcata aatagtccca
    10981 cgtttggcag gaactgtacg ggtggtttga tgaaccttct tagcttcctt cgctaaatct
    11041 gttccaaagc gagtgcctgt cccaataatg accgcaaaat tgactaaaaa aatggcaaaa
    11101 acaaagacag ataataaact cagacttttt ccaactctgc gtctgttttc agccggcgat
    11161 ttccgatttt tggtcgcata acggattact ctttttgtcc acttcatatc ttactccgct
    11221 attctaatat tttcattgtt taattgcaaa tcgtgtgaat tggcaatttc tttcaaacgt
    11281 tctgcacgta atagttcatt gacctcttgc ttggcatcgt ccaattcggt cttcttttcc
    11341 tctatctgcg cattgatttt tgtcaaatca ttctgcactt gcaagagctt ggtctgcata
    11401 aaaataatac taatggctac aataagagtg gttacagcaa tggaaaagta aaaagctttt
    11461 tccacacgcg aaaaccgttt aagttgcatc tgtagtattt gacctgtttt ttccattttt
    11521 tctgccatct ttttccctct tacttgtgaa tttttctggc cacgcgcaac ttggctgagt
    11581 gcgagcggtt attggcttct aactcttccg cacttggcaa gattggctta cgggacacca
    11641 attccatctt gggcttgaga tcatctggga tgaaaggcaa gccttttgga acttcaactg
    11701 ttgaagcttc cttgaacaat tgcttggtca agcggtcttc taaggaatga aaggtaatca
    11761 ctgaaattct accatccaga gccaacatat ccatagcctg ctggatggac tcatctgccg
    11821 cccccagttc atcattgact tcaattcgaa tagcctggaa aatctgctta gcaggatgcc
    11881 ccttcttctt gagttccttg gcaggtttga ccaacttgat aatctctgct aactcagtcg
    11941 ttgtctcaat cggcttcact tcacgcgctt gctcaatctt acgcgcaatc tgtttagaga
    12001 atttgtcctc tccatacttg aagaaaatac gaaccaagtc atgatagtca taattgttca
    12061 ccacttcata cgctgtcaga ctagcatcct gattcatccg catgtccagt ggcgcatcct
    12121 ttttataaga aaaaccacgc tcacgctggt ctaattgagg actagacact cccaagtcat
    12181 aacaaattcc atcaatttcc tgaacaccag cttcgcgcaa acatgcctgt aaatgacgga
    12241 agttgtcctt gataaaggtc accattccct tctcaatgta aggtgccaag cgtttttgcg
    12301 cattgtcaat ggcattctga tcctggtcaa aggcatagag atggcctttt tcacttaatt
    12361 tacttaataa atactcgcta tggcctgctc cacccaaagt cgcatcaacg tagataccgt
    12421 caggttttac gtcaagcata tcaatcgttt cgtggagtaa gaccgttaca tgatgaaatt
    12481 cttttgtcat atcttatcta ttttaccaca aatccgacca gcttgcactt gtcagacaaa
    12541 taggacaagg agactactat ttcttcaaaa aatatgtcaa aaatacttga cactttatgt
    12601 ttaaaagact ataatatagt caaatatata cgacataaat cagaaaggag accagatgaa
    12661 tcgtgtgaaa gaatttcgca aggaactggg catttcccag ctcgagctcg ccaaggatat
    12721 cggtgtctcg agacagacca tcaatatgat tgaaaacgac aagtacaatc caaccttgga
    12781 actctgtctc aatctcgccc gcagcctcca aactgacctc aacagtctct tttgggagga
    12841 agatttttaa aaaaggagca aactcatgaa aaaagaaacc ttcactgaaa aactgatcaa
    12901 acgcacatac ggtatttctg gtccccttga cgaatacaaa cggcgtgagg ccgatagtat
    12961 tgggaaccaa gtctttatcg tcctctttta tctgatgatt ttcggaaata ttattccact
    13021 ccttctggcc tataaatacc ctcaagaagt ggctctaatc tatcctcctc tgattttagt
    13081 gattgccctc atcgcttctg gctatgtcac ctaccaaatg aaaaaaacag gcatcacagt
    13141 cattgaacca gatatgctga atgagaaaga aagcaagcaa ctacactacc caggtctgaa
    13201 agcaggtttg ttctttggtc tatggatgtt ttttataact cctcttctca gtatactcat
    13261 agatgaaggt caggactatt ttcattctct tctcactata agaaatggtg tatcaagtat
    13321 tctcggttct attttcttcg gagcgagcat acagttcctc atctcccgtc gcattgcaaa
    13381 aactaagaaa aatcaagatg aggattagga ggaaactcat gaaaaaagaa aagaaacagt
    13441 tacgttatcc tggtctgaaa gcaggttcga tttatggaac agtgatattt tttataattc
    13501 cactcattga taccctaaca agtgaaaatc caaattttat cagttctctt ctaaatacaa
    13561 aacatatttt taaaactata ctgggagctt tctttttcgg agtgatgata catattgtcg
    13621 actcacttcg tattgcaaga gctaaaaaag accaggatta ggaggtgcct tatgaaatca
    13681 ctagctagac tactgatcat tcatgttttt atcagtattt tccttttctt cgcccttact
    13741 tcaggagcta tttctcatac agttttacta ctcctactcc tctttcttcc tgcgctcaat
    13801 aaaggacttg agaaaataca atcaaaacgg atacctgtcc tcaacgcagc cctcttcttt
    13861 ctcctcatat cctttccaca acttttaacc aaccctgtcc aatggaaatt ttcaatattc
    13921 ctagtcgtaa ccatcatttc aagtttggcc tacttctata acttttatca agtagttaaa
    13981 gaagtagatc aaaaacagtt gatttaggag cttgctccca taatttctca tttcataggc
    14041 aaataatccc acctagcttg ttctaggtgg gattatttta tttcttaaca gagattgcaa
    14101 gtcattttcc tttattttag aaagtcgact ctttccaatt cacactacaa tccaaaactt
    14161 gttgcctttc ttcttgattg cggccttcaa tctggtcaat caaaatcttt gtagcctgtt
    14221 gtccttcctc aaaggagggc tgaaccagcg tcgaaacact tggagaagaa aagcaagtcc
    14281 actccgtatt gtcaaaacca atcaacccaa cttgcggcaa gttataattc aactccttga
    14341 taacggtaaa gactagaggt agggcccaac agttagggat aaataccaga gttttttcat
    14401 cgggatcgat ttctttttgt aaaaattctt taatttgttc caaattcgta tgcttatctt
    14461 caatggttag actggcgtga cgcatattag catctgttaa agcatccaca aaaccacttg
    14521 cccgctcaat ccgagtactc aaacgactcg tatccgctgt aatcaagaga aaatgctcat
    14581 aacctttttc gatacaggac tgggtcatgt cataaacggc atcatagtta ttggttttaa
    14641 cccagctagt ccggtgttca tagagctgac tatcaaaaaa gaccattttc ttctttttct
    14701 catcgatgat acgagaatat tttcggaaat tagaggtcgg ctgaataata aagccgtcta
    14761 ctcccaagag aagcatgctt tcaatatacc ggtcctcact ctcttggctg taattactat
    14821 ttcctatcat tacctggtag ccattctggc tggcgatatc ctcaattccc ttaacaattt
    14881 ggtttgagaa actgttggta atatcaccga tcaaaacacc gattaatttt gttcgtttgg
    14941 agtttaagct acgcgcaaca atgctcggtt tgtaatttgt ttcatgaata actttttcaa
    15001 tcttttcacg tgtctcttgg gacatttttt catatttccc gtttaggtaa aatgacacgg
    15061 ttgttttcga ggtctgagcc atttccgcaa tgtcttttat ggtcagtttc ttctccaatc
    15121 taaaacacct cctactaata cttattataa catattcact attcaaaatg cctatttcta
    15181 gcactgcaag cgaatcattc tctcatttat tttatcatat actagacatt ttccacgcat
    15241 ttttgttccg tcaacgaggc acaatttttc acctacacga atatcctcgc ttaataacag
    15301 aatcagcttg tctgtttcgt catttttcac ttcaaaagcc aaagcatttt ccacttcacg
    15361 atcatctgtc tggtagacag aatgacggat gatttcaaaa ctctcatgcg caatgatggt
    15421 ataatccagc atctgattct caaagaattg gcgcttggtg agtttgctac ttctttcaag
    15481 ctcattgtat ttaggagaaa tgatggtatc ttccaaatca aaatcaactt cactccatag
    15541 tctcaactga ttgattttcc catcttgata ggtcacatcc ttgtcaagga taaactgagt
    15601 caacgcctca tgctgacctt gacacctgat gtcatctacc aagagccaga catcctctac
    15661 caacatgagg atttttctct tgtgaagata aggcaaatca ggttctgctg accaataagc
    15721 cccctcaata taatgcactc cctccctttc tttatggtga caaaacaggg agtgaggata
    15781 gtattcatat tcccaggatc ccgtgattct ttccggagct ttcccatcta caatgcaggt
    15841 cgaatgactc caagcactct ttaagagata acgttcatat atctcccgat aagaataacg
    15901 cccagcatct atgaaaatag gttggccttg atactgtaag caaaaactat tctcgtcact
    15961 atggctatgg gcacttccta gcggaccatt tttgaaaaat agataacgat gttcatcctt
    16021 aatgcagaca tgtccagagt cttcaaagat catggactta ggctgccaag ctctcttttc
    16081 aaattcctgc agtcgcttga ccttttctcg ccccaggaac aagaggctaa gcaaatcaac
    16141 tttaacatcc agaccgttaa gaaggtcttc cttgttcaaa accacagcag acaggctcaa
    16201 aatttctgtc gtttctgtag aatcgctatc accaaaagcc aaagttcgtc catctaagcc
    16261 tgtcatcatt tgaatatagg tcgccatctt ttccagcaac tctcggtaac tatcttgcaa
    16321 gtctggaagc aagagacaca aatccagtaa ggctttataa acctctacat gatagagaat
    16381 cgactgttca aactgacttc catctcctaa aatctgtgtc tcaatttgct gtttcaactc
    16441 ctctgaagca aaatggtaag cttcttctag gtccatctta tctgaaaaga aataatagat
    16501 agcaagcatc ggaattgttt gtaaaatccc ccagttacta agggtgtact tggcgcgata
    16561 gtggcttttc ataaagtcaa tctgcttttc tagactgacc aaaattttct ctagttcttt
    16621 ctcctctagc aagtcaaatt tcaagaggag caagagtagt ttcaaccaag taaaggaacg
    16681 aatacccgta tccaaggttc tagtcatcaa ggattgagga gaaaattctc tcacctgctc
    16741 aatccaatca aatagaaaga acttgcactt ttgaatatag tccttatctc cttctaccac
    16801 ataccctatc ataaactgca agagatattc ttgtcgattg agcatataag cccattctgg
    16861 atcatcttca aatacttgat cccataccat cggctggatt tgatggattt ttgaacaagg
    16921 ctccatatcc caaggactat caaacataaa acgattgtcc atcaagcgtt caagggaact
    16981 cttgactttc tcatagtctt ttgaacagtg ggacaagata taatcacgac attggtttcc
    17041 atcgattctt tcaaaaaatt gtcttctttc ttctttcatt atctattacc agaaaaagaa
    17101 ctacttaaaa agcagttctt ttgtctttcc cattacactt tccttttcta catagatgac
    17161 cacacctttt gcaatctgca aggagatcaa gtcatctttg atagaaatga tttttccatg
    17221 aattccagac aataacaaca cttcatcacc agatgttaaa gaagctaaat actcttgtcg
    17281 ttgctccatc tgtttgcgaa gcaacttttg ctgacgaata gaatgaaagc ttgacagtaa
    17341 aaggggactc actgccaaga caatcactat tccataaaac aatgttgtat ccattaagct
    17401 ataatcttaa gccagcttcc gataattccg atgataactg ttaaaataac gagtttatat
    17461 gttgtccatt tcttttcttt gatcaagtag taaactaaaa gtgtaaatag ggctggtaga
    17521 agagctggag caaccttatc aagcattccc tgaatactta cgatactttg tttagcgtct
    17581 gctttaactt cccctgcagc aaaggtaatc ggcaccataa tcttaacaga tgtcgctgcc
    17641 aaaccagcaa ttacggttac accgataata ttggcaatac gagaaatcgt tgccatctgt
    17701 tcgcttagtt tatcaatcac agttgttcct agtttgtatc catacagacc agttgacaat
    17761 ttaatcgctg ttaaaatcgt attcatcgca aggaagaaca agattggacc gacaaccaag
    17821 ccttcttgag caaacgaagc tgcgatggtt gagaacaatg gagctaaaca gaattgagaa
    17881 agagaatccc caatacctgc caatggtccc atcaaggcca tcttgatgct acgtgtttct
    17941 tttgccggac ggccattttc caacattaca agatgcaagc tggtaataaa aggcaggaag
    18001 tgtgggttgg tattatagaa ttcacagttt tcttccaagg cttggtagaa accttcctga
    18061 tcctctccat agtgtttttt caaagcagga tacatcacat tggcatatcc caacccttga
    18121 tagttactat agttaaatcc attttgacaa aagaatgccc gcaaagacgt tttaagataa
    18181 tcacgttttg ttaatttgtt agatccagtc atcgtgtgct tcctcctcta ccacatgatc
    18241 cgctgttttt ggcttgttat aaaattcaat caaagcaaag atagtaccta caattgcaat
    18301 accaattgtt gggatgttta gataagctgc acaaacatat cccaacaaga caaagggaat
    18361 caactctttc ttagccatca ctgacaagat catcgcaaaa ccgatagctg ggagcatttt
    18421 accagcaact gtcaaacctg taagtaatac cggtggaatg tagtctacga gtttcaacaa
    18481 ggtatccatt gaaagggcac ccaagcaacc caaggtaaat ccaataaagg caaacaacca
    18541 aattgttgca tttagagtga acttaaattt cttcaaatta tggtttttca agtgcttcat
    18601 cgccgtttca ggcgcaccag cacgtacagt gtaggcgaaa gtttgtaaga attgaatcgc
    18661 cacagcaatc ggagtagaga gggcaagagc cgcttctgga ctgactttac cagcactagt
    18721 gatagccatc aaggtaccaa agataccagg tccgattggg tttggtggaa cagtacctcc
    18781 agcaccaaca ccgaatccca tataagccaa ttcaccaata gctcccattg caagagcagt
    18841 aggcagatca cctagaataa ttccgacacc aaatgacaga acaatacatc tattggtgta
    18901 aattcctaat agcattccac taaaacagaa agctgtccat agtccaatta aaatcgcttg
    18961 aaatacatta atcgacataa cgatctcctc ttttaaatat agtccataat gttgacttga
    19021 acagctccat catttcctgt tggagttgtt ttcgtattaa atgttacttg atgagtttgg
    19081 cttaattcct tgagggctgc cttgtcctct tcacccagga agatggagcg tgtcacttgc
    19141 tctttaccag gggcattgtg aatgttccca atattgattt ctttgatagg gacaccacct
    19201 tctaccaagg ttaaagcgtc ctttacatcc tttacaacga taaagatcgt ttgagcagga
    19261 ttagccttgt gaatgatatc aatcaccttt tgcaaaggga agaaacgcat ggcaactgag
    19321 tctggcacaa ctgttttcat cagagtttgt tgcatcttgt ccgtgcttac ttcgtcattg
    19381 gcaacaatga ccgtattaca acctaggtat tttacccaaa gttgtccttg tccatgaatc
    19441 aaccgttcat cgatacgggt cataataata tttggcattg tcatatttct cctcctacca
    19501 atataggttc cagtctttgt agaaacggat aagggcttct aggtaatagt agtcacccca
    19561 gatattgcct tcatccactc ctttacctga atgccatgag tacacaccgt ggaggagact
    19621 tgtcccacca ggggtaaatt gatcatttgc ataatgttcg atcaaggaac gaagcatggc
    19681 atgcatagca tgtttataaa tatctttgtc agcatccacc tctgggagat gttttagcat
    19741 ttcatgaatc ccacagacgg cgatagctgt tgctgaagaa tctcgtgatt gatcactacc
    19801 atcattaaaa atcaaatccc aataggacac atgatctttt ggcagacgat tcaagaaata
    19861 attggtcaca cccttaaaca agtcaaagca ggactcgtct tttaagtgac gataagtcaa
    19921 aggaatacca taaactcccc atgactgacc acgtgcccag catgaatcat cactataccc
    19981 ttgtctcgtt acacctttaa agggttgacc tgtctcagga tcaaaataga aggtgtggaa
    20041 ggacgaagcg tcatcacgga ttacattatt agctgaagca tagaaatggc tttctgcaat
    20101 atcgtagtat ttttgatcgc ctgtttcttg ataagcaaag aataagagtt ggatattgag
    20161 caagcaatcg ataatcaaac ggtaatgctc tttcttgccc aagtctcccc aagcttgaat
    20221 aaaaccacct ttttcttgat agcgttcaat caacttatct gcagctttca aggctgcttc
    20281 tctagcctct ccatctccat ttatcttata ttcagccata caagacggtg tgtacaagaa
    20341 gccgagatca tggtgagcca attctactct cttattgaca cgatccagga aagaaagaac
    20401 atttttatga gcgatgtttt taaatgcatc ctgttgactg tattcataag ccaaccacag
    20461 ttctcctgtc cagaaaccat tggtccattc cgtgttatcc atgattggat agacattatc
    20521 aaaggtagct ggcgtcggga aatcttcctt gaaatagtca aggttgagtt ctaactgccg
    20581 aataacctta tcgattgcct ggccgacttc ttctttcgtc agaagtggta cttctaagaa
    20641 gcgctcaggc gattttattt cttcaatcgt aacctttttt atcattcttt caccctttaa
    20701 atacccgatt cgaaatcttc ttcctcttcc tctgcatccg ttgaaaacaa ttctttacca
    20761 tttacgactc cgccctgggc cgccactact gatttattaa caacttcatc aaagctatga
    20821 gccattctag caaaaactgc ttccattaac atggctaagt tcaaacccga gagaacattc
    20881 attgttttgg ctggattttc tcccattatg gtagaagaaa ccttgaatgg cgatcctccc
    20941 aagagatcac ttaggattaa aacttcttct tcatttgaaa ttgcaagtaa gattttttgc
    21001 ttgagttcat ctgctgacat tccttccaca aagtcaatcg cctccacatt ttcttgatta
    21061 cctgcaatca attgtaaaga actataaatc cctgtagcaa aatgtccatg ccctacaagt
    21121 acaattttca tcttttctcc tttcttgttt aggtttaccg gtttacttta tattccccat
    21181 tgtaatcctt tatttttatc ttgtcaatag ttttttaaaa
//
LOCUS       DAVHSH010000030        21004 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000030 DAVHSH010000000
VERSION     DAVHSH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.030"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..241)
                     /locus_tag="VVR08_001294"
     CDS             complement(<1..241)
                     /locus_tag="VVR08_001294"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6075207.1"
                     /translation="MTLRTEDQVKDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFID"
     gene            complement(264..464)
                     /locus_tag="VVR08_001295"
     CDS             complement(264..464)
                     /locus_tag="VVR08_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002839984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6075208.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIIRSAR"
     gene            complement(710..988)
                     /locus_tag="VVR08_001296"
     CDS             complement(710..988)
                     /locus_tag="VVR08_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075209.1"
                     /translation="MKKDKEVYDNVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1202..2833)
                     /gene="rlmD"
                     /locus_tag="VVR08_001297"
     CDS             complement(1202..2833)
                     /gene="rlmD"
                     /locus_tag="VVR08_001297"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6075210.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2907..3881)
                     /locus_tag="VVR08_001298"
     CDS             complement(2907..3881)
                     /locus_tag="VVR08_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU6075211.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3955..4569)
                     /gene="pmp23"
                     /locus_tag="VVR08_001299"
     CDS             complement(3955..4569)
                     /gene="pmp23"
                     /locus_tag="VVR08_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU6075212.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4569..5543)
                     /locus_tag="VVR08_001300"
     CDS             complement(4569..5543)
                     /locus_tag="VVR08_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU6075213.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5551..6807)
                     /locus_tag="VVR08_001301"
     CDS             complement(5551..6807)
                     /locus_tag="VVR08_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU6075214.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(6869..7300)
                     /locus_tag="VVR08_001302"
     CDS             complement(6869..7300)
                     /locus_tag="VVR08_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6075215.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7302..7904)
                     /locus_tag="VVR08_001303"
     CDS             complement(7302..7904)
                     /locus_tag="VVR08_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU6075216.1"
                     /translation="MMDRIRQELEKGGAVILPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7888..8727)
                     /gene="prmC"
                     /locus_tag="VVR08_001304"
     CDS             complement(7888..8727)
                     /gene="prmC"
                     /locus_tag="VVR08_001304"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU6075217.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNFN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(8727..9806)
                     /gene="prfA"
                     /locus_tag="VVR08_001305"
     CDS             complement(8727..9806)
                     /gene="prfA"
                     /locus_tag="VVR08_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU6075218.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9803..10393)
                     /locus_tag="VVR08_001306"
     CDS             complement(9803..10393)
                     /locus_tag="VVR08_001306"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU6075219.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10517..10699
                     /locus_tag="VVR08_001307"
     CDS             10517..10699
                     /locus_tag="VVR08_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU6075220.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAIVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10837..12210
                     /gene="mnmE"
                     /locus_tag="VVR08_001308"
     CDS             10837..12210
                     /gene="mnmE"
                     /locus_tag="VVR08_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU6075221.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTNSFAIAQKIFKGKDL
                     SQVASHTLNYGHIVDPLTGKVMDEVMIGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12257..13192)
                     /gene="dapA"
                     /locus_tag="VVR08_001309"
     CDS             complement(12257..13192)
                     /gene="dapA"
                     /locus_tag="VVR08_001309"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU6075222.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13248..14324)
                     /locus_tag="VVR08_001310"
     CDS             complement(13248..14324)
                     /locus_tag="VVR08_001310"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU6075223.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14666..14738)
                     /locus_tag="VVR08_001311"
     tRNA            complement(14666..14738)
                     /locus_tag="VVR08_001311"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14703..14705),aa:Thr,seq:ggt)
     gene            complement(14838..15347)
                     /locus_tag="VVR08_001312"
     CDS             complement(14838..15347)
                     /locus_tag="VVR08_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU6075224.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15345..15441)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15470..15901
                     /locus_tag="VVR08_001313"
     CDS             15470..15901
                     /locus_tag="VVR08_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU6075225.1"
                     /translation="MKKPIQKFFNNEILAYLFFGIVTTLVAILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15983..16360
                     /gene="mscL"
                     /locus_tag="VVR08_001314"
     CDS             15983..16360
                     /gene="mscL"
                     /locus_tag="VVR08_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU6075226.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTDEKKPTELEVLQEIKALLEKK"
     gene            complement(16402..17496)
                     /gene="hemH"
                     /locus_tag="VVR08_001315"
     CDS             complement(16402..17496)
                     /gene="hemH"
                     /locus_tag="VVR08_001315"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU6075227.1"
                     /translation="MKKAILMMTFGSPEEIIFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGSEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17651..18871
                     /gene="pepT"
                     /locus_tag="VVR08_001316"
     CDS             17651..18871
                     /gene="pepT"
                     /locus_tag="VVR08_001316"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU6075228.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(18914..19543)
                     /locus_tag="VVR08_001317"
     CDS             complement(18914..19543)
                     /locus_tag="VVR08_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075229.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE"
     gene            19508..19729
                     /locus_tag="VVR08_001318"
     CDS             19508..19729
                     /locus_tag="VVR08_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075230.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19838..20407)
                     /locus_tag="VVR08_001319"
     CDS             complement(19838..20407)
                     /locus_tag="VVR08_001319"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6075231.1"
                     /translation="MLEITLKSPYQFAHILFQPTIVPHGGHYHFIPESDLSAGELAAT
                     YVFNPNDIVRDTGDAYIVRHGDHYHYIPKSSLNNPPSHSNTEEVGSSSSSVLSNTSLH
                     VHHEEEDGHGFDANRIISEDSEGFVIPHGDHNHYIKVQTKGYEAALKNKIPSLQSNYQ
                     PGTFDEKAVLAKVDQLLADSRSIYKDRLS"
     gene            complement(20451..21004)
                     /locus_tag="VVR08_001320"
                     /pseudo
     CDS             complement(20451..21004)
                     /locus_tag="VVR08_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6074 a         4377 c         3895 g         6658 t
ORIGIN      
        1 catcaataaa aatttgtttg ctaatatctc tttcttctga ttttgtttca aggattattg
       61 ctacatcatt catattttta ggtaaatacc aaccatctgg cttatctgaa tatcccttga
      121 agcctaattg attaaaagta gttatttgac cagtaccttg attgatgttt tcttcaactt
      181 cattaaagcc taatacttct cttgcataat ccttaacttg atcttctgtc cttaaagtca
      241 ttttctattc ctcgtcacta aaattatctt gcactcctaa taatatcatt aggagtgcaa
      301 gataaagcct tacatattct ttctaaattc ttaaatgtaa ttggtttatc ctttcccatt
      361 tgtgccataa catttgttgt aagtcctgcc atagctatta catctgtttt ctttagtcct
      421 ttttttgcta actgtatcca taatggttta tagttaagtg ccataatatc cctctttttt
      481 tcttcattag atttatttaa ttatagcata aatattgatt tcattcaatc ttacattgat
      541 ttagtgattt gttttagaga atttgttgtg ttattccgtc cttattttgc cataaattgt
      601 tttaagtggg acctcttatc cttaccattt ttacctccta attttgagta taaaaaagac
      661 gatagagttt ttaatttcta tcgtctgaga tttacatatt aaattttcat cacaaaataa
      721 gactctttaa agaatcttta aattcattgg tatgctgctt acaatatcca ttattaaaat
      781 ggatactata agcagcacac caactattta ttttttgagt tttaaacttt ggtagaagtc
      841 ttgaactcct tatatttaca taactatttg cctctataac tattatgaca cgaaaccaac
      901 aagcaagttc aagcacctcc atatctttat tcaaatgagg actaagatat tcacaaacat
      961 tatcataaac ctctttatct tttttcataa aagaggcata caacttagca aatttatcct
     1021 aaaatttttt gttgccttta tcaatcattt caacgctcct ttaaatataa aaatgatcct
     1081 atcaatcttt atattgagcc tattttctaa ttgatacctt gcaagaaagg aataatagct
     1141 gttcctatac caagtaggaa tgtaataaat gcagaaagtc atatactgtc attcttttct
     1201 attaaatcat tttgaagtgt ctcaaagcat ccatgatggc ttcttctttt tcaggtgtac
     1261 actgtggaat aatttgttta tcctttttag acttgttgta atgttctcgt aattctattc
     1321 cacatttctt ttttatctgt gcaatatata atgtcgaaac ttttaattca aatttattcc
     1381 aaacatattc tttgatttga gcatatgttg ctttgctctc cgcacttgtc aaatccatct
     1441 catccagctc aatttcaaca cttatatgct tatcgacatc gagtttggac aaaagtgcta
     1501 ccgtctcgac gtgatgcgtt tgaggaaata gatccaccgg ctggactttc ttcaattcat
     1561 atcccaactc ttggtatagt ttaatatcac gcgccatggt tgcgacattg caggagatat
     1621 aggcgatgcg atcggctcct gtttgggcgc ttgctttgat aaagctttct gtcaagccct
     1681 tgcgtggagg atcaaccaag ataacggttg gttgaatccc atctttaagc caattcttca
     1741 tagcattttc agctgtgtca cagacatagt gggcgtttga aatattgttc agctgagcat
     1801 tttttttact attctcaacc gcttctggaa tcagttcaac accgtagact tctttgacat
     1861 gcttggcgac tgataaacca atggttccaa taccagaata ggcatcaata atcacgtcat
     1921 ctttttttaa ctctgcaaag tcaatggctg tttgatagag tttctccgcc atttcagtat
     1981 tgacttggta aaaggctggg ccagcgattt ggaagtcatt tcccaacatc tggtccgtaa
     2041 tatagtcttg accataaaga gtgcgccact ccttaccaaa aatcgcattg gtattctggt
     2101 cgttgatatt ttgcatgaca gacacaatct ctgggaactg cttgataact tgttcaatca
     2161 attggtcaac acgaaaaact tttggacgag ttgtcaccaa aacgaccatg atttgtcctg
     2221 aatagtgacc acgacgcacc acaagattcc gaatcaatcc agactgttcc ttttcgtcat
     2281 aaggttttaa atcaaaacga cggagcaggt ctcgaagagc tactacgact tggtcaatga
     2341 caggatcctg gataaagaaa tcttcaaggg gcatgaggtt gtgcgaattc ttacggaaaa
     2401 atcctgtttc caagacacca ttcactcgac gaacgggcac ctgcgcctta ttgcgatact
     2461 tgactggatg ttccatacca agcgtttcag caacttctac atctgcaatt ccagcaatct
     2521 tgtagagact gtccttgact tgcttggttt taaacttgag ctgttctgga taagaaaggt
     2581 gtcctaaatc cgcgattcct gaacgcaggt aagccaaatc tagatcttga ttacggtgtg
     2641 gtgactggac aaggtatttt tcaacttttc caaagccaat ctttttattg accttgagga
     2701 cacgcatgag aattttttca ctcggtaaag cattctctac aaaaaagacc aaaccatcta
     2761 ccttggcaac tcctgcccct tcatgggtca aatcaacaat ttcaacttct acaatatcat
     2821 ttttctttaa cattcttttc tctttctatt ggccgacaaa aaagacggca acgttacggt
     2881 taccatccat tataccatga aatttcttaa gaaccaaaac tcttgaagaa gttgacaagg
     2941 gcttgccaga gggagcttaa gaagttacca ccgtcctcta gcgccttatc cgcatcaaag
     3001 ttaaggttga tatttttaaa actgtcgcca gcttgtgata cgatgctttg tttaaggtca
     3061 tttagggttt tagtgaaatc tgcattgctg aggatatcac tctttgagag attcaaggca
     3121 aaattgatga tgatattgat ctggtttcct gttatgacct gatcaagttt gtaatttttt
     3181 aaggtatctt caacaatctt gcggatatct tcttctgtca gatttccctt gctttcttta
     3241 gctttggcga gtcctgactt gatatcagct agggcaacgt ttaatttatt agcatcatag
     3301 cctgatttgt ccttgttttc agcattgata tctgacaaag cctttagctc ttcttgagcc
     3361 aaatctttat tggcttgcgg caccttggct ccattagctt ctagcgaata gtagatccca
     3421 gccaaagcac tctcacctgt aactggaatg ggtgctgcta cagtgatttt ggcgtgttcc
     3481 acacccaaag ttacggctgc atttcggtac atatcctgag ttaccttagt gatgttttca
     3541 ggtgtttcaa tcttgacctc aagtggcgat ttgtcaccta gcttttgaat cttggctgat
     3601 gaatacaact gtaagctaga gtcattggcc acattcatga ttttagaata aacatcaggt
     3661 gtcatggtct tgagttcttt ggtatctgtt gaggcattgt agcccagttt tttaagagtt
     3721 tgattttttt ggtcttcaga tagggaagaa cctaggacat attcaggttg gacataggtt
     3781 tcatcgataa ctttttgaac atctgttgct gcatggacgc tattcatagc tgttactgcc
     3841 cacaagatcg cagcgctagt cagaaagagt ttctttctca tagggaattt cctcctttac
     3901 ttctttagag taatatatct atcttaaaga aaacttataa caaaaacacc tggtctagcc
     3961 agatgttgaa aagagagtga aacatttgat gatgtaaagg ttaagtcgta cctgtctaga
     4021 ataataatag tttcctccat ttacatagag ttcagcaccg tgaaaaatgg aaatggggtg
     4081 aatataacta taagtctttc cagtcgtatt accaagcaag ggggcaacag tctcacgaga
     4141 gtactgtttg gctagagcca aggtattttc cttgccattt tgggcgataa aatcgatata
     4201 ggcaggtcca aaattatagg cttgaacagc tgtccagata tctacaccct tcttctgcgc
     4261 cagatagaga ttgcctgtca gagtttgaat gccttgccga atgctagagg cattatcatt
     4321 gatggtgttg gtggaaccac ttgcagactc actagactgc ataacatcgc cttcttttcc
     4381 ttttgtttca gtataaatca tagcaagcac aagctcttcg tttgctgggg tgtctttttc
     4441 actcaatatt tctcgcacca tgggttgata ggtcatgact tgtttgacat cttgatgaac
     4501 gcggtaagct ttatagccag caaaaaggaa gactgctagt acaagcactc ttcgaattcg
     4561 tttaaacatt atttactttg gatatcctcg atatttttga ttaagataga gtaggttcca
     4621 ttttcgtttt ggataaactc aacagactcg gcgtcttgat agacgttatt gggaacgatg
     4681 agctcaattc catttgataa ggagagtttt tggttttcaa atttctttaa ttggcgactg
     4741 acatcaattt catcaaattg aacaggttct ggtacggctt ctttgacttg gtcaataaag
     4801 ctcaaacgag ccgtcagatt gttgtcaaaa aggtcattag ccaatttctc aggtgacaat
     4861 tcattgcttt cttctaggtt gttgaaaata gctgatttga ccttggattg aaattgaaaa
     4921 tcatctgtgt taaaagattc agcaattctc tgggctgttt tttccagttc cttgatagat
     4981 tttttaggag aaatcttagg agcgacagca agaagattat ctgaaaaata gttcaaaaaa
     5041 gtcccgttgt acttgattcg tttttcaatc aggtgatact tgctactctg aagattgacc
     5101 accaaggcct catcagctcc tgttccaaat ccaggcaggt tattctgagt tagcttgatt
     5161 ggattatcaa cttctcctcc gaggtgggtc aaggtctccc gcagggcaat tcgcaagaaa
     5221 gcgaaatgtt ctacaccttc tttagaaaat tgaacaaaaa tcaagtcatt ggtcttgaga
     5281 ttttcagaaa tgctaaactc ctctttccag agattagcca gcgttactga tgtctccaac
     5341 aaatcgtctg taatatgatt gaagaaggga ttttcttctt cgaaaatccc agtcttggct
     5401 tcatctgaat acacatgttc aattttttta cgcaggtatt cttcgatttt tggagtaata
     5461 ttgagaaact tatctgctaa gaacagttcg gtatcatccg gactgaactg gtgaataatg
     5521 gctttcttaa tataaatgtc cataaaagtt ttagtcctcg tatagtagga aggcatctgt
     5581 caattctttg actgcacttc tcacttcttc taatacagcc tcattttctg aattcttaag
     5641 ggttttaatg atgagttcag ccactttgcg actttcttct tcaccaaatc cacgtgcagt
     5701 aatggctgct gctccgatac gaatcccact tgtcttgaat ggtgacaagc tttcgtaagg
     5761 gattgagttt ttatttaagg taatattgac ttcatccaac aagttttgag caactttgcc
     5821 gttttctaca actttagtca catcaacaag gaagagatgg ttttcagttc cacctgaaat
     5881 aatacggaaa tcagggtctt gcaagaagac atctgccata gccttgctgt tcttaattac
     5941 attggcagca tattccttga aggctggatc caaaacttct ttgaaggaaa ctgccttagc
     6001 cgccacaaca tgctctaaag gaccgccctg aatacctggg aaaatagctg aattgatttt
     6061 tttagcaagt tcttcgtcat tggtcaaaat caaaccacca cgaggaccac gaagggtttt
     6121 gtgggtcgtt gttgttgtga tatgagcgta tggaactggg cttggatgaa ggccagccgc
     6181 aaccaaacca gcgatatggg ccatgtccac catgagcttc gcaccgacag catctgcgat
     6241 ttcacggaat tttgaaaaat cgataatttg agaatatgct gaagcaccag ctacaatcag
     6301 ttttggtttt acttcttggg cttgtttcaa gatagcatca aagtctaaga gttccgtttc
     6361 aggatcaaca ctataagaaa caaagttgta ggtttgacca gagaagctaa caggagcccc
     6421 atgagtcaaa tgaccacctg atgccaaatc cattcccata accgtatcac ctggctcaat
     6481 caaggacatg taagccgcac agttagcttg gcttcctgaa tgtggttgga cattggcaaa
     6541 tttagcaccg aaaatttctt ttgcgcgttc aatagcaaga gtctctacaa cgtctactac
     6601 atcagttcca ccataataac ggcgtcctgg gtaaccctcg gcatatttat ttgtcaagat
     6661 agacccttga gctgccataa cagccttgga aactacgttt tccgaagcaa ttaactcgat
     6721 attattttgt tggcgttctt cttctttggc aatagcattc cagagatcag catcatatgc
     6781 tttaaaatca tctttgtcaa aaatcatagg tcttctcctt tattgtgtga ctagtccatt
     6841 agtttgattt tacaataaga aaatcaaact aaaagatgcg aataaaccgt ttctgcattt
     6901 tatcacaagt atagccaact ttttcataaa atgcatgagc acccagacga tgattggcag
     6961 aatttaagcg gataaaccca taaccacatc ttttggcttc ttgttccaac ccttgtagta
     7021 aacttttacc gataccttca ccttgcgctt gaggtgaaac tgctaaagct aagatattaa
     7081 atcctgcttt ggaatagagt gattcgtaaa cttcagcgtg gacatatcca agtaagacat
     7141 gattagctgc atcctcatag ccaagtagga aatgatggga atcctgagac agtctagcta
     7201 gttggctagc cgtttcctct ggactaaaag tataacccaa agcctcttgg ttgatgtcac
     7261 atatcgcttt cacatctgtt tcttgcaaat ctcttagcat ttcaagcctc ctcaaaagaa
     7321 atctctggca accgagcaag aatatcttct cgtttaattg cgccttggcg taagattttc
     7381 accttgtctc cagacaaatc cacaatagtt gaatcctgtc cagttagaaa agcatcgtct
     7441 tccagaccca gaacctcttg gtcaaaatcc ttcagaattt gttcaaaggt tacaccactt
     7501 gcctgacctg agatattggc agacggccca atcaagggac ctgtctctcg aattaaatcc
     7561 agtgtgatag ggtgactggg catccgaaat ccaatagttg caaggtcaga atttacccaa
     7621 tagggaactc ggtcattggc ttcgagaata atggtcaagg gacctggcaa aaaggtctct
     7681 acaagttttt gtagataagc tggctgattc ttagaaaagt gcaagatatc ctctaaagag
     7741 gcgatattga gattgagtgc cttatctcta ggacgacgtt tgagctggta aacatggtca
     7801 actgcttttt cgtctaaggc cttggcaaaa agaccataaa ccgtctctgt aggcagaatg
     7861 acagctccac ccttttccaa ctcttgtcta atcctgtcca tcatcaacca cgaccatcct
     7921 atcttgacca aattggtcct tgagtgttcg aactcttttt tcaggaagat gtttcctaaa
     7981 aagttcggga acactttgac cttgcttgta tccaatttca aggtaaatct taccaccatc
     8041 cttgagatag tcttttgcat cttccgcaat tctacagtaa atagctaggc catcctcgtc
     8101 tgcaaagaga gctagatgag gctccgaatg caaaacattc aagcctacct ctgactcatc
     8161 ttcacgagag atatagggtg gattggatac aattatatca tatttttcag aaatttctgc
     8221 aaaacaatca gattttttaa aaaatatatt aaaattttga tcgctagcat tctctgatgc
     8281 aagctctaag gcctcttgag aaacatctgc tgctgtcact gaccaatctg gtctattttt
     8341 tgctagagcg agagcaatag ctccactacc tgttccaata tccagaactg agagattcgt
     8401 ctcaagattt tcagttagaa taagctccac taactcctct gtttctggac gaggaatcaa
     8461 aacccgttca tccaccttta aatgcattcc ataaaaatct gcctgtccaa tgatgtactg
     8521 agctggcttg tgagctgcta gttgctggta aatatcttct acaaattgtt tttcttcctc
     8581 tgttgtcacc tcctgctgga gggcaaaaat aaagtctgta aaagatagat ttttcagact
     8641 acgatagaca aaagagaggc tttccgcttc ctctccttgt cttatcaact cttcttcaaa
     8701 atttgaaaac aattgagcta atttcattat ttgtttaatt cttctagttt ttgtgtttgg
     8761 tcataaagca ccaaggcatc cacaacttcg tccaatttac cagacaaaat cgtatctagt
     8821 ttttggagag tcaagccgat acggtggtct gtgacacggt tttgtgggaa gttataagtt
     8881 cggatccgtt ctgaacggtc accagtaccg attgtcgact tacgctcagc gtcttgttca
     8941 tcctgagcaa tctgagcaaa gtggtcagcg acgcgtgcac ggataatctt catagccttc
     9001 tcgcggttct tctgctgggt acgttcttcc tgcatctcaa ccttgatatt ggttggcaag
     9061 tgaacgatac gcacggcagt cgcaacctta ttgacgttct gtccaccagc accagaggcg
     9121 tgatagatgt cgacacgaag gtcttttgga tcaatgtcgt attcaacctc ttcaacttct
     9181 ggcataacaa gaactgtcgc tgtcgaagta tgaacacggc cttggctttc tgtcacagga
     9241 acacgttgca cacggtgggc acctgattca tacttaagct tagagtatac agactgacct
     9301 gaaaccatag caaccacttc tttgaaacca ccgacaccat tcatagaagc ctccatgact
     9361 tcaaagcgcc agccttgggc ttcagcatac ttttggtaca tagttagcaa atctccagcg
     9421 aaaagtgccg cttcgtctcc accagctgct ccacggattt caaggatgat attcttgtca
     9481 tcgtttggat cctttggaag gagcaaaatt ttcagttttt cttcatattc ttctttttca
     9541 gccttggcat ctttgagttc ttgcttggcc atttcttcca agtccgcatc tccacctgat
     9601 tccttaatca tctcttcggc atcgacgata ttttgaagga cttgtttata ctcacggtag
     9661 gctattacgg tgtcacgatt ggaggcttct tcttttgaaa gctccataaa acgcttggtg
     9721 tctgaaacga catcagggtc actcagcaat tctcctagtt cttcataacg gtcttctaca
     9781 gcttgtagtt gatcatagat gttcattttt cttcattctc cttattgatt tcaggggcaa
     9841 aataatgttt acggcaaacc gagatatagg tttcattacc accaatctgg atctgttctc
     9901 catcgtaaac gggcagtcca tcctgtgttc gcaacaccat ggtcgccttt ttcttgcaat
     9961 actgacagat ggtcttgatt tcgtcaatct tgtccgctaa aagcaagaga tatttggaac
    10021 cttcgaacaa ttcattgcga aagtcatttt tcaagccaaa agccatgacg ggtatgtcta
    10081 actcgtctac aacacgagct aggtcgtaaa catggtggcg tttgagaaac tgggcttcat
    10141 cgaccaaaac acagtaaggt ttttctggta ggtctcggat atagccaaag atatccgttg
    10201 tttcctcaat cgcaagggca gggcgtttca tgccaattcg actcgacaca tagccaacac
    10261 cgtcacgcgt atccagagcc gaagtcataa tgacaacacc ttttccttgc tcctcgtagt
    10321 tataggccac tttgagaatc tcaatcgtct taccagagtt catggtccca taacgataat
    10381 acaactgtgc catgtttctt gcttcacgtc catttctaaa tttttgctac attctagtat
    10441 atcataattt tctgaagctt taaacggcaa aatgtggtaa aatagaagaa atcaaaaact
    10501 agtggaggaa gctattatgc catttgtacg catcgattta tttgaaggac gcacgctcga
    10561 gcaaaagaaa gctcttgcta aggaagtaac ggaagctatt gtccgtaata ctggagcccc
    10621 ccaatctgct gtccatgtca tcatcaacga catgccagaa ggaacttact tcccacaagg
    10681 ggaaatgcgt accaaataag ctagcttaag cagaattgct taggcttttt caatctccaa
    10741 gtaacatcca ttgaagaaat agcctaaatt tgttacaatt tgaaaggata cttggaaaaa
    10801 tttccaagaa aagagctatt tattaaagga aacattatga ttacacgtga atttgatacc
    10861 atcgctgcta tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga
    10921 acaaacagtt ttgctattgc gcaaaagatt ttcaaaggaa aagacttgag tcaggttgct
    10981 agccatacac ttaactacgg tcacatcgtt gaccctctga ctggtaaagt catggacgag
    11041 gtcatgattg gggctatgaa atctccaaaa accttcactc gtgaagatat tatcgagatt
    11101 aacacccacg gtgggattgc ggtgactaat gaaattctcc agctagctat ccgtgaagga
    11161 gctcgattgg ctgaacctgg tgaatttact aaacgtgcct tcctaaatgg acgtgttgac
    11221 ttgactcagg ctgaggcagt aatggatatc atccgtgcta agacagataa agccatgaac
    11281 attgcggtca aacaactaga tggttctctt tctgacctca ttaacaatac ccgtcaagaa
    11341 atcctcaata cacttgccca agtcgaagtt aatatcgact atcctgagta tgatgatgtt
    11401 gaggaagcga ctactgctgt tgtccgcgag aaaactatgg aatttgaaca attgctaacc
    11461 aatctcctta ggacagcccg tcgcggtaaa atccttcgtg aaggaatttc cactgccatc
    11521 atcggacgtc ccaacgttgg gaaatctagc ctcctcaaca atctcttgcg tgaggacaag
    11581 gctatcgtta cagatattgc tggtaccaca cgtgatgtca tcgaagagta cgtcaacatc
    11641 aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga tgacatagtg
    11701 gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt ggttctacta
    11761 gtgctaaatg ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa
    11821 gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg
    11881 aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt
    11941 gaagagcgaa tcaacaacct cttctttgaa aatgctggct tggtcgagca agatgctacc
    12001 tacttgtcaa acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc
    12061 gttaatcaag gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt
    12121 acttgggaaa tcctcggaga aatcactggg gatgctgctc cagatgaact tattacccaa
    12181 ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg
    12241 gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg
    12301 cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg
    12361 gaacaagagg tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa
    12421 ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa
    12481 ttgctgcggc tttcttcata tcgctttctg caatcgcagt aaacatctcg tgcatttcat
    12541 ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga
    12601 aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt
    12661 aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca
    12721 agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa
    12781 taattggtag gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag
    12841 aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta
    12901 cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag
    12961 gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg
    13021 tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca
    13081 ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc tcatggaagg
    13141 gggtaataaa ggctgtaatg attttacatt tttttaaatc ttgataagac acgaaaacac
    13201 ctttctattt caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca
    13261 aatttcaatt cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga
    13321 actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct
    13381 ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca
    13441 ttgatagctt gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag
    13501 gctgcgatag ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca
    13561 gactcagagt gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta
    13621 tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca
    13681 ttatcagtga aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg
    13741 tcaccacctg aaggcaagat ttccgcatgc aaatcacgtg gtttcacacc atcattcaag
    13801 acttcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct
    13861 tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc
    13921 accatcattt gaattgttga acaattaggg caggcaatga ttccgttgtg agcatcaagt
    13981 gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat
    14041 gtattatcta ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta
    14101 gaactacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct
    14161 tcaattgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca
    14221 aggtaacgaa ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca
    14281 ccgacagcac ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg
    14341 aattttctaa aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc
    14401 tttttcatca ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat
    14461 cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc
    14521 tcatgctcaa tagtagtccg aagactacct atcgactcat cgcatattct atattactag
    14581 agatacttga ttttgtcaat aagaaatttt tcagatcgag tataacaaaa aactctcgta
    14641 ttcaagagtt tccctataca tatcatgcta attgccggga ttgaaccggc gacctcatcc
    14701 ttaccatgga tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat
    14761 tcagaaaaac ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaaaaact
    14821 acctagctta tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata
    14881 atcgctccaa taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag
    14941 aatggtaatt ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag
    15001 aggattgaaa agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta
    15061 tattttgcaa aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca
    15121 aagacatcta gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg
    15181 atgatgtact taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga
    15241 taagcaccat agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca
    15301 gcgacgattg caatatctgc aacatcacga atagttaatt ttttcatctt ttctcctttg
    15361 gcggttatcc gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgattcatt
    15421 caaccttact agtatagcac aatagcctgc tttatgctat acttaaagca tgaaaaaacc
    15481 tattcaaaaa ttttttaaca atgaaatctt agcctatctc ttttttggta tagtgactac
    15541 tcttgttgct atactatcac gattagtcat ttatcagcta agtcatcagg aactccttgc
    15601 tacggccttg gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt
    15661 atttaagcaa aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgcccgcct
    15721 ttctactttt ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat
    15781 catagggcaa ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc
    15841 acaaatattc attattatca tcaattatat cttgagcaag gtctatattt ttagaaaata
    15901 atgctccatt tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac
    15961 gaaacattga aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa
    16021 tgttattgac cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc
    16081 acttgtaaac gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt
    16141 tgaacgtatc gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat
    16201 tatcaatttt atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc
    16261 acagaagctg actggcataa aggaagaaaa aactgacgaa aaaaaaccaa ccgaattgga
    16321 agtccttcaa gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg
    16381 caaagctaaa tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt
    16441 tttgataaga taaggcatct taacattttc acgacctttt ttctcaatca attttttcac
    16501 aaattctggc atttgtaaat cttgagattc agccaaaatg tttttcgtct cgtctgaagg
    16561 aactaactca tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt
    16621 gactctaact gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg
    16681 acgatggtag tttaccccaa attcctgaca taagtcataa cattccacat cattgtcaaa
    16741 caagacctca atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg
    16801 ttctgtctgt tctctgagat actccaaaac atctggttta atccatggaa taccaatatc
    16861 actctcactt tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac
    16921 tagcttgcta ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat
    16981 aggcacacta tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa
    17041 aatcttagca atttcatctg cccaatagtt taagagcgct tcttcctgat accagtcctt
    17101 aatgaccaaa aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta
    17161 gaaagaataa tggggctcca aaatcaagca aatacactgt tcaattccgt ctgcttccat
    17221 ttgaccgatc acatctggaa taaagggact ggaaaactta ttagcaaagt agacactgta
    17281 ttcactcccc agcctagctt ctaccaaggc aacctcttga cgggtaattt tttgcagagg
    17341 cgtgcctcca attcgtacat aattatcata aagagtctga atctcgtggt cttggggtct
    17401 caccccacga cgaatatttg tgaaaaaatc agctacacct tcaaagataa tctcttctgg
    17461 tgaaccgaag gtcatcatta aaattgcttt tttcatgact gcttccttgt gatgttttta
    17521 tcaagtttat tttatcatta attcatcgat aagtaaacgc tagcataggg acattctcaa
    17581 tcttctgtct tttgtttttc tcttctttct atgatacaat ggaaaaaata aattcaaaag
    17641 gagttttttt atgacttatc caaatctctt ggaccgcttc ttaacctatg ttaaggtcaa
    17701 cacgcgctct gatgaacact ctactactac tccaagtaca cagagtcagg ttgacttcgc
    17761 aacaaatgtc ctaattcctg aaatgaaacg tgttggactg caaaatgttt actatctacc
    17821 gaatggtttt gctattggaa ccttgccagc caacgatccg tctttaacac gtaagattgg
    17881 ttttatatcg cacatggata ctgctgattt taatgctgaa ggagtcaatc cacaggtaat
    17941 tgaaaactac gatggtggtg tgattgaact agggaattct ggtttcaaac tcgatccagc
    18001 tgacttcaag agtcttgaaa aatatccagg acaaacgctc atcacaacag atggaacaac
    18061 cttgctaggt gctgatgaca agtcaggaat tgctgaaatt atgacagcca ttgaatatct
    18121 aactgctcat cctgaaatta agcactgtga gattcgtgtt ggttttggtc cagatgaaga
    18181 aatcggtgtt ggtgccaata aatttgatgc agaagatttt gatgtggatt ttgcctacac
    18241 tgttgatggt ggtccactag gtgaacttca gtacgagact ttctcagccg ctggtgctga
    18301 attgcatttc caaggtcgta atgtccaccc tggtactgcc aaagggcaga tggtcaatgc
    18361 ccttcagcta gcaattgatt ttcataatca acttccagaa aatgaccgac ctgagttaac
    18421 tgaaggttac caaggttttt accatctaat ggatgtgaca ggtagtgttg aggaggcgcg
    18481 tgcaagctac atcattcgtg attttgaaaa agatgccttt gaagcgcgta aagcatccat
    18541 gcaatctatc gctgataaga tgaatgaaga acttgggagc aaccgtgtca ctctcaactt
    18601 gacagaccag tactacaata tgaaagaagt cattgaaaaa gatatgactc caattaccat
    18661 tgctaaagcc gttatggaag atctaggtat cacgcctatt atcgaaccaa tccgaggtgg
    18721 aacagacggc tctaagattt cctttatggg aatcccaact ccgaatatct ttgcaggtgg
    18781 cgaaaatatg cacggacgtt ttgaatacgt tagccttcag actatggaac gtgcagttga
    18841 taccatcatt ggcatcgtac gtagcttata aaagctaaaa agacgaggta gctcagctac
    18901 ttcgcctttc tttttattct actggttttt cttgatttcc agtagttgta gaagattctg
    18961 ttgttttatt ttctgaagtt gattcagcag gtttagaatc tcttgtattg cttggtttgt
    19021 tttcgtcgct agcagtttca atgttagatt ctgcagttgc gtttggttgg ttctcagcac
    19081 tggtgttatc accatttgct tcagcatttc ttgctggact tgtttcttca cttgcgctag
    19141 cttttgactg gatttgatga ttcaaaacta gaatagcttt tgtcgattca agtaaagctg
    19201 ttttgtcttt actcttagca gaaagttgat ctaataatgc atccacctta tcaaagtccg
    19261 catcagatcc attattactt tctaaataag agtgaagcga catgagaata tcgtagagtt
    19321 tttgatagag tacaagtgtc tgaggatctt gctcagcatt ttccttttct tgttgaaggg
    19381 cgctagcgat acgagtcaaa acatctttta cctgactgtt tacttcatcc aagtctgcat
    19441 cagccttgtt tgtggcagct tttagatttt ctacttcttc tgccaaggat tgtctgattc
    19501 cttcttcatg gatttgttcc aagagttgat ttgccttgtt caaaagactt tctacttctt
    19561 ccttgctatc tgtcgcagat tattggttgc tatctaccat gtactcctaa aacaggagag
    19621 ttataatcca agattacaag gccttacaga aataagaaat ccagataaga caatgttcgt
    19681 ccaagacgct attcgcttcg cacagcagca cggattcaat atgctttaat tttaaagttt
    19741 aggtgtcaag acctcttttt agtgtgccca aaatttagag aagtaatcaa tcaactaact
    19801 tttatttttt tcaaactttc agtaaactga cctaaagcta actcaatctg tctttgtaga
    19861 tgcttctgct atcagctaga agttgatcta cttttgccaa gactgccttc tcatcaaaag
    19921 ttccaggttg atagttggat tgcagggatg gaatcttgtt tttcaaagcc gcttcatatc
    19981 ccttagtttg aaccttgatg tagtgattgt ggtcgccatg aggaattaca aaaccttctg
    20041 aatcttcact tataattcga ttggcatcaa aaccatgacc atcttcttcc tcatggtgga
    20101 catgtagtga cgtattactt aatacagaac tagaagaact tcctacctct tccgtgttag
    20161 agtgtgatgg gggattgtta agagatgact taggaatata gtgatagtga tccccatgtc
    20221 ttactatata agcatcacct gtatctctga caatatcatt agggttaaag acatatgtgg
    20281 ctgctaattc acctgccgac aagtcactct caggaatgaa atgatagtga ccaccatgtg
    20341 gtactatagt aggttgaaat agaatatgag caaattgata aggggatttt aaagtaattt
    20401 ctaacaatga tttagaaact atgatgtgct attctaaatt caactcacta tatataacca
    20461 tcatcggtag tataacgtcc ctgtaatttt gctacagata cttctgcact agctccttta
    20521 tcgtctttac catgttcttg tttttggcga ttgatttcat cttttgttcg tacattttct
    20581 gcatgagctt gatctttaag gtaaacataa tactttccat ctaccttaat aatatatcct
    20641 cccttaacct aactgacgat atcttgatct ttcggctgat agttgggggc tttcattaat
    20701 agctcttcac taaagagcgc atcaaaagga actttaccat tatagtagtg ataatgatcg
    20761 ccatgagaag ttacataacc ttgacctgta atcttaataa caatttgttt tgcttgaatt
    20821 ccttcttttt gactaaccta gtctggagtc aaattttcag tcttcttagt gtctttatta
    20881 ctgtttacat atgaaacacg atttttatct gtattggcct gttagctatg ttggttcaga
    20941 gcataaacac acagacttaa ggaaaggata acaacagatc cagctgctat atatttcttt
    21001 ttaa
//
LOCUS       DAVHSH010000031        20746 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000031 DAVHSH010000000
VERSION     DAVHSH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.031"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            113..3214
                     /locus_tag="VVR08_001321"
     CDS             113..3214
                     /locus_tag="VVR08_001321"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU6075232.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3297..4304
                     /gene="pfkA"
                     /locus_tag="VVR08_001322"
     CDS             3297..4304
                     /gene="pfkA"
                     /locus_tag="VVR08_001322"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU6075233.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4363..5868
                     /gene="pyk"
                     /locus_tag="VVR08_001323"
     CDS             4363..5868
                     /gene="pyk"
                     /locus_tag="VVR08_001323"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU6075234.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6559..6784)
                     /locus_tag="VVR08_001324"
                     /pseudo
     CDS             complement(6559..6784)
                     /locus_tag="VVR08_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7632..8504
                     /locus_tag="VVR08_001325"
     CDS             7632..8504
                     /locus_tag="VVR08_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU6075235.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTESTTDVKVHAEKMEAFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8650..8994)
                     /locus_tag="VVR08_001326"
                     /pseudo
     CDS             complement(8650..8994)
                     /locus_tag="VVR08_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9137..9448
                     /locus_tag="VVR08_001327"
     CDS             9137..9448
                     /locus_tag="VVR08_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075236.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKECEELRQIITTIFEQKMNKHSI
                     K"
     gene            9452..10168
                     /locus_tag="VVR08_001328"
     CDS             9452..10168
                     /locus_tag="VVR08_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6075237.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEEFICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10297..11112)
                     /locus_tag="VVR08_001329"
     CDS             complement(10297..11112)
                     /locus_tag="VVR08_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU6075238.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVISFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQVTNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11109..12014)
                     /locus_tag="VVR08_001330"
     CDS             complement(11109..12014)
                     /locus_tag="VVR08_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU6075239.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSIVVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSHLSPAKKVFQVFVQAIDEFFDTGRYLVFGCLFASVIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            12426..14555
                     /locus_tag="VVR08_001331"
     CDS             12426..14555
                     /locus_tag="VVR08_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU6075240.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14542..14991
                     /locus_tag="VVR08_001332"
     CDS             14542..14991
                     /locus_tag="VVR08_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU6075241.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLT
                     NSHSKPLKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            15050..15322
                     /locus_tag="VVR08_001333"
     CDS             15050..15322
                     /locus_tag="VVR08_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6075242.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15675..15866)
                     /locus_tag="VVR08_001334"
     CDS             complement(15675..15866)
                     /locus_tag="VVR08_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075243.1"
                     /translation="MKHKEHILIGLLYLLSSFIGQLLVEKTYFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16294..17052
                     /locus_tag="VVR08_001335"
     CDS             16294..17052
                     /locus_tag="VVR08_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075244.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTTENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17054..19042
                     /locus_tag="VVR08_001336"
     CDS             17054..19042
                     /locus_tag="VVR08_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075245.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMNVVIAVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19084..19728)
                     /locus_tag="VVR08_001337"
     CDS             complement(19084..19728)
                     /locus_tag="VVR08_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU6075246.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(19754..20692)
                     /locus_tag="VVR08_001338"
     CDS             complement(19754..20692)
                     /locus_tag="VVR08_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU6075247.1"
                     /translation="MLQKANKGKSNREIASLLGKAPQTIHTEIKRRTVRQCLGKGRFK
                     EVYSADYAQQFYENNRKHSVKRSSVTKELKEKILHYHNQKFSPEMMVMAKGVNVGIST
                     IYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQSIEQRLEAINFRLENGHYE
                     IDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVNQALKLILKQHKILSITADN
                     GTEFNRLSNVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEK
                     WINNYPKKCLDYKSPREDFLMANLNLKFSVRNKSRN"
BASE COUNT         6305 a         3777 c         4393 g         6271 t
ORIGIN      
        1 aatacaaatg aatagaaaat aaattagtaa gctgatgaaa tttttctcaa gagaagccat
       61 ttataggtga aaatggtata atatagtgag aaggatagag gagaagtgta aattgatcgc
      121 acaactagat acaaaaacag tctatagttt tatggaaagc gtcatttcga tcgaaaagta
      181 tgtgagagca gctaaagaat acggctacac tcatttggct atgatggata ttgacaatct
      241 ttatggcgct ttcgactttc tagagattac aaaaaaatac ggcattcatc ctttgctagg
      301 gcttgaaatg acagtgtttg tagatgatca ggaagtgaat ttgcgctttt tagctctatc
      361 tagtgtgggc tatcagcagt tgatgaagct ttcgacagcc aagatgcagg gggagaaaac
      421 ttggtcagtc ctgtcccagt acctggagga tatcgcggtc attgtgcctt attttgatag
      481 agttgagtcg ttagaactag gctgtgatta ctatataggg gtttatccag aaacactagc
      541 aagcgaattt catcatccta tcttacctct ttatcgggtc aacgcttttg aaagcaggga
      601 tagagaagtt cttcaagttt taacagcgat taaagaaaat ctaccgctca gagaagttcc
      661 cttgcgttcg agacaagatg tctttatatc agcaagttct ttagagaaac tattccaaga
      721 gcgttttccg caagctttgg acaatttaga aaagcttatt tcaggcattt cttacgactt
      781 ggatactagt ctgaaactgc ctcgttttaa tccagctaga ccagcagtag aggagttgag
      841 agagcgtgct gaactggggt ttgttcagaa ggggttgact agtaaagaat atcaagatag
      901 actagaccaa gaattgtctg ttattcatga tatgggcttt gatgattatt tcttggttgt
      961 ttgggatttg ttgcgttttg gacgatcgaa tggctattat atgggaatgg gaaggggttc
     1021 tgcagtaggc agtttggttt cttatgcctt agacatcacg gggattgacc cagtagagaa
     1081 aaatctgatt tttgaacgct ttcttaatcg tgaacgctat accatgccag atattgatat
     1141 tgatatccca gatatttatc gtccagattt tatcagatat gttggtaata aatatggtag
     1201 taaacatgcg gcacaaatcg ttactttttc aacctttgga gccaagcaag ctctacgaga
     1261 tgtcttgaaa cgctttggtg ttcctgagta tgaattatct gcaattacta agaaaatcag
     1321 ttttcgtgac aatcttaagt cggcctatga gggaaatctc cagtttcgtc agcaaatcaa
     1381 tagtaagtta gaataccaaa aagcttttga gattgcttgc aagatagagg gctatccaag
     1441 gcaaacctct gtccatgcgg ctggtgttgt aattagtgac caagatttaa ccaactacat
     1501 tcctctaaag tatggtgatg aaattccact gactcagtat gatgctcatg gagttgaggc
     1561 tagcggactt ttgaagatgg actttctggg actacgaaat ttgacctttg ttcagaagat
     1621 gcaagagttg cttgctgaaa cagaaggtat tcatctgaaa attgaagaaa tcgatttaga
     1681 agacaaagaa acgttagctt tatttgcctc tggtaataca aaaggtatct ttcaatttga
     1741 gcaaccaggt gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg aagatgtcgt
     1801 cgcgactact tctctaaatc gaccgggtgc tagtgactat atcaataatt ttgtggcaag
     1861 aaagcatggg caggaagaag tgactgttct ggatccagta ctggaggata ttttggctcc
     1921 aacctacggc ataatgctct atcaggagca ggttatgcag gttgcccagc gatttgccgg
     1981 atttagtctt gggaaggccg atattttgcg tcgggctatg gggaaaaagg atgcctctgc
     2041 catgcatgag atgagggctt cctttattca aggttcatta gaagctggtc atactgtgga
     2101 aaaagcagag caggtctttg atgttatgga gaagtttgca ggctatggtt ttaacaggtc
     2161 acacgcctat gcctactcag ccttggcctt ccagttggct tattttaaaa cacattatcc
     2221 agccatattt tatcagatta tgttaaattc tgccaacagt gattacttaa tagatgcact
     2281 tgaagcaggt tttgaagtgg cgcctctgtc catcaacacg attccctatc acgataaaat
     2341 tgccaacaag gccatctatc taggtttgaa atccattaaa ggagtcagta atgatttagc
     2401 tctctggatt attgaacata gaccttattc taatattgaa gattttatag ctaaattacc
     2461 tgagaattat ctgaaacttc ctctgctaga acctttggta aaagttggtc ttttcgattc
     2521 atttgaaaaa aatcgtcaaa aagtatttaa taacttagct aatctatttg aatttgtgaa
     2581 agagttggga agtttgtttg gagatgctat ttatagttgg caggaatcgg aagattggac
     2641 ggaacaagaa aaattttata tggaacaaga gcttttaggg ataggtgtca gcaaacatcc
     2701 actacaagct attgcaagta aggctattta cccgattacc ccaatcggaa atttgtcaga
     2761 aaatagctat gctattattt tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa
     2821 gggtgaaaat atggccttct tacaggcaga tgatagtaag aaaaaattgg atgtcactct
     2881 cttttcagac ttatatcgtc aggttggaca ggaaataaaa gagggagcct tctactatgt
     2941 aaaaggaaaa atacaatcac gtgatggccg tctgcaaatg attgcacaag aaataagaga
     3001 agcagttgct gaacgctttt ggatacaggt gaaaaatcat gaatcggatc aagaaatttc
     3061 acgtatttta gaacaattta aaggcccaat cccagtcatc atccggtatg aagaggaaca
     3121 gaaaaccatc gtttctcccc atcattttgt agctaaatcc aatgaattag aggagaaatt
     3181 gaatgaaatc gttatgaaaa cgatttatcg ctaaaaatac ggaaaataga agaattttaa
     3241 aatcaaatgt gatataatca agaagaatgt taaaagaaaa aggagcataa accaatatga
     3301 aacgtattgc tgttttgact agtggcggag acgcacctgg tatgaacgct gctatccgtg
     3361 cagttgttcg tcaagcaatt tcagaaggaa tggaagtgtt tggtatctat gacggatatg
     3421 ctggtatggt tgccggtgaa attcatcccc tagatgcagc ttcagtagga gacatcattt
     3481 ctcgtggtgg tacttttctt cactcagctc gttatccaga gttcgctcaa cttgaagggc
     3541 aacttaaagg gattgagcaa ttgaaaaaac acggaattga aggtgtagtt gttatcggtg
     3601 gtgacggttc ttaccacggc gctatgcgtt tgactgaaca tggcttccca gctattggtc
     3661 ttccaggtac aatcgataac gatatcgttg gtactgactt tacaatcggt tttgacacag
     3721 cggttactac tgccatggac gctattgata agattcgtga tacatcatca agtcaccgtc
     3781 gtacttttgt aatcgaagtt atgggacgta acgctggtga tatcgctctt tgggctggta
     3841 ttgcaactgg tgctgatgaa atcatcatcc ctgaagcaga cttcaagatg gaagatatcg
     3901 tagcaagcat caaagctggt tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg
     3961 aaggtgtgat gtcagcggct gaatttggtc aaaaacttaa agaagctgga gatacaagcg
     4021 accttcgtgt aacagaactt ggacatattc aacgtggtgg ttctccaact gcgcgtgacc
     4081 gtgttttggc gtcacgtatg ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg
     4141 gtgttgcggt tggtattcgt aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag
     4201 aagaaggggc attgtttagc cttactgcag aaggtaagat tgtggttaac aacccacaca
     4261 aagccgatat tgagctatct agcttgaata agagcttgtc ataatttaca atttagttaa
     4321 taagaccaaa aaggtcatat atataaagga gtcacaaaaa tcatgaacaa acgtgtaaaa
     4381 atcgttgcaa ctttgggtcc tgcggtagaa atccgtggtg gtaaaaaatt cggtgaggac
     4441 ggatactggg gtgaaaaact tgatgttgaa gcttcagcta aaaacattgc taaattgatt
     4501 gaagctggtg ctaacacatt ccgattcaac ttctcacacg gcgaccacca agaacaaggt
     4561 gagcgtatgg caactgttaa acttgcggaa aaaattgcag gtaaaaaagt tggtttcctt
     4621 cttgatacaa aaggacctga aatccgtaca gaattgttcg aaggtgaagc taaagaatat
     4681 tcatacaaaa ctggtgaaaa aattcgtgtt gcaactaaac aaggaatcaa atcaactcgt
     4741 gaagtgattg cgttgaacgt tgctggtgct cttgatatct atgatgatgt tgaagttggt
     4801 cgtcaagttt tggttgacga tggtaaactt ggtcttcgtg tggttgctaa agatgatgaa
     4861 actcgtgaat ttgaagttga agttgaaaac gatggtatca tcgctaaaca aaaaggtgtg
     4921 aacatcccta acactaaaat tcctttccca gctcttgctg aacgcgataa cgacgatatc
     4981 cgtttcggtc ttgaacaagg tatcaacttc atcgcaattt cattcgtacg tactgcaaaa
     5041 gatgtgaacg aagttcgtgc aatctgtgaa gaaactggaa acggacatgt tcaattgttc
     5101 gctaaaatcg aaaaccaaca aggtatcgat aacttagacg aaatcatcga agcagctgat
     5161 ggtattatga ttgctcgtgg tgatatgggt atcgaagtac cgttcgaaat ggttccagtt
     5221 tatcaaaaaa tgattatcaa gaaagtcaat gctgcaggta aagttgttat cactgcaaca
     5281 aacatgcttg aaacaatgac tgaaaaacca cgtgcaactc gttcagaagt atcagacgta
     5341 ttcaacgctg ttatcgacgg aactgacgct acaatgctgt caggcgagtc tgcaaacggt
     5401 aaatacccac tcgagtcagt aactacaatg gctacaatcg acaagaacgc tcaagctctt
     5461 cttaatgaat acggacgtct tgattcagat tcatttgagc gtaactctaa gacagaagta
     5521 atggcttctg ctgttaaaga tgctactagc tcaatggata tcaaattggt tgtaactctt
     5581 actaagacag gtcatactgc acgtttgatt tctaaatacc gtccaaatgc tgacatctta
     5641 gcattgacat ttgacgaatt gacagaacgt ggcttgatgt tgaactgggg tgttatccca
     5701 atgttgacag atgctccatc ttcaactgac gatatgttcg aaatcgctga acgtaaagcg
     5761 gtagaagcag gtctcgttga gtcaggcgat gatatcgtta tcgttgctgg tgtgccagta
     5821 ggagaagctg ttcgcacaaa cacaatgcgt atccgcacag tacgttaaga aaaatataaa
     5881 aacctatcat atccagcttt ctagtctgta tgatgggctc tttttttgtc caggggggca
     5941 aaaagggggc aaaactttca taatggattg atactcttcg aaaatcaaat tcaaaccacg
     6001 tcagcgtcgc cttaccgtac tcaagtacag cttgcggcta gcttcctagt ttgctctttg
     6061 attttcattg agtatgaaat aagatatgca caaattgatt aggaaattca aatgaatttc
     6121 tacaaatgtt ttagcaatcg taatgtactt gtctagattc gatctgatat attttcgatt
     6181 taatgatatg gtatttaaaa cctccaaagt agcttgctcc attcttttac ttacgtgagt
     6241 gtagatgtta tttactgttt tagcgttttt gtgttccact ctaaccatta tagcattctt
     6301 ctcagctagt gtactaagga gtgtgtgcct gaaaatatgg gaactaaggg gctggtttat
     6361 cggtttctct agtttagtat ttgccttttg caaagtgatg ttaaatgcct ttctctaaat
     6421 ttacatatca ctattgttta acaaaatcta atctacttta ggtcacttat tctttttttg
     6481 aaatgtagaa tgaacttttt caaagttttt cgaatctttt aaaatctgtt tgttttatat
     6541 cgccattctc cccctttttt aattctccct atatagcctg acaactttcc cgatggtacg
     6601 aatatggttg ctttcgtcta ggtggatgtc ggggtatttg ggattgagtt tttttaaggt
     6661 agccttggcg gagtttcttg acatagttag cgccgtctac ttggaagatg ccgatggtat
     6721 tatagtcaat ctgtggggta ttcttgataa ataggtagtc gctgtttctt atctttggct
     6781 ccatggactt gctgatgaca taagcgattg ggtcgtagtc gtctgggata atggaaactc
     6841 catatctaaa tcgttgtcct gcatcgagcg gctacctgca gagataaact atctaacacg
     6901 agagtaagta gtctgtctgt agtcgtccag tctgatgatt tttacgatac ttcgtttttc
     6961 tgatcataca gttgcctctc ggcataggtc agaactttac cttgtctgga tggtgcccgt
     7021 tggtcgtaga tagattggat atcgctagga gaatcctttt gaactggaga aaagagggca
     7081 tcaatcaagc tactgaatac tttaactaag tcaaatatag tatttttctt agtagaccta
     7141 accctttttt cataatttcc aatggtgttt ttacttatac caatcttagt acccaattct
     7201 tattgagttc aaccattact agtctatatt gttttatagt tgattgagtt tggaatagta
     7261 cgctgtagct gctaaaacat ttctaggaat taatttgcct ttcctaatag agttgttcat
     7321 atcttatttc aatctactat atttttcgcc tctaacaatc gcaatctctt ctttatctac
     7381 gaacgaaatc gctttctatt tttgtaagta aagcatcaca cgaaatccac gaaaatgaaa
     7441 acctttgttg tgttttcgta aaaaatttgt tgacagagca cgaaacgcct actataatta
     7501 aatcaagctt aaggaaataa caaaaaaaca aatcggaggg aaagacgatg aacacattaa
     7561 atgagaaagt aatcaatatc tgtaaagcaa tagttaaaga aactttaatc caagacattt
     7621 aggagaaaga aatgaagaaa tcaagaaaat tagccacatt aggaatctgt tcagctttgt
     7681 ttttaggctt ggctgcttgt caacaacaac atgctacttc tgaggggacg aatcaaaggc
     7741 aaagcagttc agcgaaagtt ccatggaaag cttcatacac caacctaaac aaccaggtaa
     7801 gtacagaaga ggtcaaatct ctcttatcag ctcacttgga tccaaatagt gttgatgcat
     7861 tttttaatct cgttaatgac tataatacta ttgtcggctc aactggctta tcaggagatt
     7921 tcacttcctt tactcacacc gaatacgatg ttgagaaaat cagtcatctc tggaatcaaa
     7981 agaagggcga tttcgttggg accaactgcc gtatcaatag ttattgtctt ttgaaaaatt
     8041 cagtcaccat tccaaagctt gaaaagaatg accaattgct tttcctagat aatgatgcga
     8101 ttgataaagg aaaggtcttt gattcacaag ataaggaaga gtttgatatt ctattttcga
     8161 gagttccaac tgagtcaact acagatgtca aggttcacgc tgaaaagatg gaagcattct
     8221 tctcacaatt tcaattcaat gaaaaagctc gaatgctgtc tgtagtcttg cacgacaatt
     8281 tggatggcga gtatctgttt gtaggccacg ttggggtctt agtacctgct gatgacggtt
     8341 tcttatttgt agagaaattg actttcgaag agccctacca agcgattaaa tttgctagta
     8401 aggaagattg ctacaagtat ttgggcacca agtatgcgga ttatacaggc gagggactgg
     8461 ctaagccttt tatcatggat aatgataagt gggttaaact ttaatagtgt tatgatatga
     8521 cagtaatctt aggattttta tttctatttt tgataagttg gtgggttatt tcaatcgtta
     8581 atagccagaa accacgcaaa aatgaaacat ttattggcta tgtccaaaga tacgatattg
     8641 atgggaatgg ctatcaatca ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt
     8701 aacaccactt tgaacaagag ttacttcaac ccattggctc cgacggatta agttgctttc
     8761 gtgaatacca aaatcagccg caatttgttc ataagtgcgg tattctcgca catattgaag
     8821 agtggccata agaaggtctt ctaggcttaa tttaggtttt cgtccacctt ttgcgtgttt
     8881 aagttgataa gctgttttta atacagctaa tatctcttca aaagtcgtgc gctgaacacc
     8941 aacaagacgt ttaaatcgtg catcagttag ttgtttactt gcttcataat tcatagaact
     9001 actataccat attttgtttc gcaggaagtc taatgctaaa atcttatcag tgagaagatt
     9061 tcttaaagtt tattctttgt agtttcatct gtattagtac ataatttaac ttagagaaaa
     9121 taggaggact aatcgaatgg aattaaaaga ttttacagaa aaagaacagg aaatgattaa
     9181 gaaaaggctt acaatgtcta atattagtga caaagaaact actgagaaga ttctggcgct
     9241 agtaccacaa gacttgatta agcgaatccc gttttttgtc agaaaacatg ctacaacacg
     9301 tacgattaaa cgcatttcaa ttgaacaccc tgaactctac gctgtagctc aaacaagtgg
     9361 tgagattcca gaaaaagaat gcgaagaatt gcgtcagatt atcacaacta tctttgaaca
     9421 aaagatgaat aagcatagta ttaagtagag aatgaaaaaa tattttattg gcggtttggg
     9481 aagcaatgcc tatcatagca aggattttct tcaagaacta gattcgcagg tctattttct
     9541 aaatccatat gaaaagcatc ttcgagatga aacagaattg aaatcatggt ttaaaaatga
     9601 gattgtagag gaagaattta tctgtctgat aggtcattct cttggaggag atttagctcg
     9661 ttatctcgca tcggaatttg aagaagtaaa gaaactgatt cttttggatg gtggctatct
     9721 agatttagat aagattttac ctttggatac agagttagag gaaactaaaa attatatcaa
     9781 atctcaaatt gttttggact tagatgttct tacttctaaa gaaaaatctg aagcaaagca
     9841 ttggtcagaa aatatggaga aagctgtaag acagtcctat cactggaatg ttgagtataa
     9901 tagatatgag ttggctataa attatgaaaa tatagaagcg atactccgcc tacggagaaa
     9961 aatacaagct tttaagagag aagtgggaga taccttgttt attagtcctc gctatcctaa
    10021 tgaagctaca tggagagagg aagccctaaa agaattgcca gactattttg atactatttt
    10081 tttagaaaac tttggccatg agctttatac tcaagcacct aaagaaatcg ctagtctaat
    10141 gaatgagtgg ctcgcttatt ttctatgagc tacttgtatt gctggaaatg gtataagatg
    10201 aaaatctaca agtcactaat tttcatataa caaaaaacga acaggctctt tttctgttat
    10261 tcagaagaga acttgttcgt ttttatcttg attttcttaa aaagctctat atacataggg
    10321 attttctggt ttatcgactt tggtaaagct gtcgatttcc aaggttggaa ggttttgttt
    10381 gagttcttta tggtagtgat tgaccagttt tcctttggct gttatccaag tgttgttttc
    10441 atactgccgg gtattgccct tggtcagcaa tccatagaca ccagaatctg cgatacagtg
    10501 gataatgccg aatcggaaca gaaattgact attggcatga ctggggtcgt tatagacaaa
    10561 gcctgtaaac tggattgtct tgccctcaaa ctcatctgga tagtcgtaga tagcctccat
    10621 gacttccata tagttttcat tagtgacctg aatactatct tgggataagt atttatccgc
    10681 cgccgttcgc atttcctttt cataggctga ttttgaaaaa taagaactgg tatctggttt
    10741 caaatattgg cttgtcgtcc cttcgcttgt ctgaatggct agatccgttc cttccgatag
    10801 ggggaaatga taacctttag cagaaacagt ctgagaatcc aagctaacag ttgggaaagt
    10861 taagccgatg acaagtggaa tagccagaag agaaatactc gtcatcttgg ctaatcggct
    10921 gttcagatga ctgtgggttt tgacttgctt catccagata tacaattgaa cgatagccaa
    10981 gataaaagaa atcaccatgg agatataggc cagataggaa tagtgcatgt tgatgtactg
    11041 gtttagtttg cccgacagat ggaggtaaat agtcagttca aaatagccag ctaaaactaa
    11101 aaatcgaatc ataggatgac tccaatcaag agagaatagg ctaaaacgac cagagtcaca
    11161 atcgtaatga agtgactaat aaatcgtgct ttcaagtaat ttttcatcat aagaatattt
    11221 ttgatatcca gcattgggcc aatgacgaga aaagccagaa ctggagccaa accgaaactc
    11281 gagagtagag aagccccgat aaaggcatcc gcctcactac agagcgaaag aagaaaggcc
    11341 aaaatcatca agagcaggat ggcaaaaaga ggagtcgcac tgatagaggt cagaatccga
    11401 gtcggaacat aaacctgtat aacagaggca aagagacagc caaataccaa ataacgtccc
    11461 gtatcaaaaa actcatcaat ggcttgcaca aagacctgaa aaactttttt tgcaggactt
    11521 aagtgagaaa aatcatgctc atgacaggct agacgatttt ctttttgaat cggttcttgc
    11581 cagaaaaatc ctagaaaaat tcctagtatt acagccacaa cgatggaacc cagagctcgt
    11641 aatagggcga catggaagga gttgccaaag gcagaatagg tcgcaaaaag aacaatggga
    11701 ttgataacag gtgctgtcac aagaaaagga acggccgtgt aacttggaac ctttttttcc
    11761 agaaaacgat tgatgatggg gacgattcca cattcacagg aagggaaaag tataccgaca
    11821 aaggtcccaa aaaagattct cccccaacga tttcgaggga gaaaatgata aaccttgtca
    11881 ggtgtgatat aaacttcaat cagccctgag acaatacttc ctatcagaac gaagggaagg
    11941 gcttcaatga taatggagag aaaaatggct ccagtttgaa gtacactaga tgggagttgt
    12001 tgaaaagcag tcatctagtt tttcttttct gctttggctt ttttctcttt gtcatcaggg
    12061 aaagtgactt gtttcaaatc agggagttta gcaaactctt caaacatctt gtccaagtcg
    12121 tctcgttttg taaatttgac agccataggt gtacctcgat tctaaattct acctctatta
    12181 tactattatt ttgcggaaaa gggagttttt taatttgttt tcgatagttg atactcttcg
    12241 aaaatctctt caaaccacgt cagcttcgcc ttaccgtagt acggttactg acttcgtcag
    12301 ttctatccac aacctcaaaa cagtattttg agcagcctac ggctagcttc ctagtttgct
    12361 ttttgatttt tattgagtat gaaaaggatt ggagaaagcc ttccagcttg tggtataata
    12421 gatttatgga taaaaaatat gaaaaaatct ctcaggattt gggagtgacg ttaaagcaaa
    12481 ttgataccgt tctaagtttg acagctgaag gggcgactat tccctttatc gcgcgttatc
    12541 gcaaggacat gactggtagt ctggatgagg tggcgattaa ggctattatt gatttggata
    12601 aaagtctgac aaatctcaat gaccgtaagg aagctgtctt agctaagatt caagaacaag
    12661 gtaagttgac caaggaattg gaagaagcta tcttagttgc cgaaaaatta gcagacgttg
    12721 aagaactcta tcttccttat aaggaaaagc gtcgtaccaa ggcaaccatt gcccgtgaag
    12781 ctggactctt tcctcttgct cgtttgattt tgcagaatat agttgactta gagaaagaag
    12841 ctgaaaagtt cgtctgtgaa ggatttgcga ctggcaagga agccttgacc ggtgcagttg
    12901 atattttggt cgaagcctta tcggaagatg tgaccttgcg ttctatgact tatcaggaag
    12961 tgctgagaca ctctaaactc acttctcaag ccaaggatga aagtcttgat gaaaagcagg
    13021 tttttcagat ttattatgat ttttcagaga cagttggaac tatgcaaggc tatcgtacct
    13081 tggctctcaa tcgtggggag aaacttggtg tcttgaagat cggttttgaa catgcgacgg
    13141 accgtattct tgccttcttt gctactcgtt tcaaggtgaa aaatgcttat attgatgaag
    13201 ttgttcagca atccgttaag aaaaaggtct tgcctgctat tgagcgtcgt attcggacag
    13261 aattaactga gaaagctgaa gagggagcta tccaactttt ttctgacaat ctgcgcaatc
    13321 tcctcttggt tgctccactg aaagggcgcg tggttcttgg gtttgaccca gcctttcgta
    13381 caggtgccaa gctagctgtc gtggatgcaa caggaaaaat gctgacaact caggttattt
    13441 atcctgttaa accagcatca gctcgtcaaa tcgaagaagc caagaaagat ttagcagatt
    13501 taattggtca atatggtgta gagattattg ccattggaaa tggaacggcc agtcgtgaaa
    13561 gtgaagcttt tgtagcggaa gttctgaaag atttccctga agtcagctat gttatcgtta
    13621 atgaaagtgg tgcttctgtc tattctgcca gcgaacttgc tcgtcaggag tttccagact
    13681 tgaccgttga aaaacgctct gccatttcta tcgcccgtcg tttgcaagat cctcttgcgg
    13741 aattggtcaa aatcgatcct aagtcaattg gtgtcggtca ataccaacac gatgtcagtc
    13801 agaagaaact atctgagagt ctggactttg ttgtcgatac agtggttaac caagttggtg
    13861 tcaatgtcaa tacagctagc ccagctcttc tttcacacgt agctggactc aataaaacca
    13921 tttctgaaaa tatcgtcaaa taccgtgagg aagagggaaa aatcacttca cgctcccaaa
    13981 tcaagaaagt tcctcgtttg ggggccaagg cttttgaaca ggctgctggt ttcctccgta
    14041 tccctgaaag tagcaatatc cttgataata caggagttca cccagaaaat tacgctgccg
    14101 ttaaggaact cttcaaatgc ttggacatta aggatctgaa tgaagaggcc caaagcaaac
    14161 tcaagtcgct ttcagtcaag gaaatggcgc aagagttaga ccttggtcca gaaactctta
    14221 aagatatcat tgcagatctt ctcaaaccag gtcgagattt ccgtgattcc tttgatgctc
    14281 cagttctccg tcaagatgtc ctagatatca aggacttagt ggttggacaa aagctagaag
    14341 gagtggtgcg taacgttgtt gatttcggtg cttttgttga tatcggaatt catgaggacg
    14401 gtctcatcca tatttcccat atgagtcgca agtttatcaa acaccctagt caagtggtgg
    14461 cagttggaga tttggtgagc gtttgggtta agaaaattga tactgaacgt gaaaaagtta
    14521 atctgtctct cctagctcca aatgaaactg actgattacg tcaagcaggt ttcactagaa
    14581 gacttcggca gaccttttat ccatcatgtc cagtggaata ggcgtctacg ttcgacaggt
    14641 gggcgatttt tccccaaaga tgggcatttg gattttaatc ccaaggttta tcaggaactg
    14701 gggttggacg tttttaggaa aattgtccga catgaactct gtcattatca cctctatttt
    14761 caagggaaag gctatcaaca caaggatcgg gattttaagg aactgttgaa agcagtggat
    14821 ggattacggt ttgtaccatc cttgacaaat agccactcta aaccactcaa actttatcgt
    14881 tgccaatcct gccagcaaac ttatcagcgt aagcgtagga ttgataccaa acgctatcgc
    14941 tgtggacttt gtcgaggaaa gttgctatta gtaaatcagc ctgaggactg atgaaagccg
    15001 agcctatccg tgatatacta tgtctaacct agcagaaaga ggaaatatca tgaacagtaa
    15061 gttttataaa atgagacgaa atcgcatgat ttcaggagtt ttagcaggtc tgtcagacaa
    15121 gtggaacttt gatgttaccc ttgtacgttt tctgtttgcc atttttacag tcgcaaactt
    15181 tggacttggg gtgattatct atatcatcct agcttctatc atgccaacca aggaagaaat
    15241 cgaagcagaa atgtacggaa caggcccacg taaacgcaaa gaagctcaag ccattgacga
    15301 taatgaaggc tggttttggt gaggttttac aaaagatttg gaatacgcaa aagctttaaa
    15361 tcaatagtct aaactgcttg atttaaagct tttttacttt tatactcaat aaaaatcaaa
    15421 gtgcaaacta ggaagccagc cgcaggctgt aatttagtcg gcaatgtgaa gttgatatag
    15481 tttgcacttt gatttttgaa tagtattaat aatatttcgc cagcttcatc cacaaactat
    15541 agtggattgg aactagaata ggacacctat acttctaaaa aattgttaga aatcgatttg
    15601 actgtcctga tcgatttgtc ctgttcttat ttcattttac tataaaagca gtaatttaaa
    15661 cgcagttttt taatctattt ttgctgctga gacaatacat ttttggaaaa atggtggatg
    15721 ctgataacaa ctgataacca gcaaataaca taagcagtgc cggtaaattc tgtaccgata
    15781 aagtatgttt tttcaactaa gagctgaccg atgaatgaag agaggagata gagaagtccg
    15841 atgagtatat gttctttgtg tttcattaag gcgcaccttc tttccttata ggttgaacga
    15901 cttgcaagtg ttaaattgaa tggtatgtta tctaggtaac cttactaaaa tgttagttcc
    15961 cgcttcctcc ttttcaaagt aagccttttc acacttatat tttacaactt taaaaatagg
    16021 aaatcaaatc attttctaag taattttgct tatatttcac ccaatcttac aaaaatgtaa
    16081 gattaaagtc tcttttgtaa ggttaggtta tggcaagcgg tctttttttg atgtaaacta
    16141 gattcataaa gaacaaagga gtaacatcat gaaacaaatc ttacataaga aaactagaaa
    16201 accaagtcac aaagaaattg agcgcgttca gctgggatgc actatgatgc aagctacatt
    16261 tcatttgatg ggatattaag aaaggagatt ctcatgacac ttttagatgt aaaacacgtt
    16321 caaaaaattt ataaaacacg ttttcagggc aaccaagtag aggccctcaa ggatattcac
    16381 tttaccgtag aaaagggtga ctatgttgcc atcatgggtg agtctggttc tggtaaatcc
    16441 actcttctca atatcctagc tatgctggac aaaccaagtc gtggtcaggt ttacttaaat
    16501 ggaactgata cagcaactat taaaaattca caagcttcta gcttccgtcg tgaaaagttg
    16561 ggctttgtct tccaagactt taacttgcta gatactctgt ctgttaaaga caatatcttg
    16621 cttccacttg tcttgtcaag aagacctatt acggaaatga tgaagaaatt ggtggtgaca
    16681 actgaaaatc tgggtatcaa ccaattgcaa gagaagtacc cttacgagat ttctggtggc
    16741 cagaaacagc gtgtagcagt agcccgcgcc atcatcacag aacctgaaat tctccttgcg
    16801 gacgagccaa caggagccct tgattccaag tcatctgcag ccttacttga tgtctttaat
    16861 gaaatcaatg agcgtgggca aaccatcctc atggtaaccc actcaacagc agctgctagc
    16921 agggccaagc gtgttctctt tatcaaggac ggcattcttt acaatcaaat ctaccgtgga
    16981 gagaagacag aacgtcagat gttccaagaa atctctgata ccttgactgt catggcaagc
    17041 gaggtgaatt agtatgtttc gattaaccaa taagttagcg gtatcgaact tgattaaaaa
    17101 ccgcaaactc tactatcctt ttgcgctggc tgttctcttg gcagtcactg tcacctatct
    17161 cttttactct ctaaccttca atcccaagat tgcggaaatc cgtggaggaa caaccattca
    17221 ggctacactt ggatttggta tgtttgtcgt cacccttgcg tcagccatta tcgttctcta
    17281 tgccaatagt tttgtcatga agaaccgttc caaggaacta ggaatttatg gcatgttggg
    17341 cttggagaag cgccatctaa tcagtatgac ctttaaggag ttagtggtat ttgggattct
    17401 aactgttgga gcgggtatcg gtattggagc cttgtttgac aagttaattt tcgctttcct
    17461 gctcaaacta atgaaactga aggttgagct ggttgctacc ttccaaatga atgttgtcat
    17521 tgcagtactt gttgtctttg gattgatttt cctaggcctc atgttcctga atgctcttcg
    17581 aatcgcccgt atgaatgccc tccagctctc gcgtgagaaa gcaagcggag agaaaagagg
    17641 tcgcttccta cctctccaaa cgattcttgg ttccataagt ttagggattg gctattatct
    17701 tgcccttacg gtaaccgatc ctcttacagc cctaacaact ttcttcctag ctgttttgct
    17761 ggttatcttt ggtacttatc tattgtttaa tgcagggatt acagtcttcc tacaaatctt
    17821 aaagaaaaac aagaaatact attaccaacc taataacctc atatctgttt ccaacttgat
    17881 tttccgtatg aagaaaaatg cggttggact agcaaccatc gctattttgt caacaatggt
    17941 tttggtaacc atgtcagcag cgacaagcat tttcaattcc gcagaaagct ttaaaaaagt
    18001 tctaaatcct catgattttg gggtttcagg gcaaaatgtt gaaaaagaag atttggacaa
    18061 actcttgagc cagtttgcaa gtgacaaagg ttatagtgtc aaagagaaag aagtacttcg
    18121 ttacagtaac tttggtattg caaatcaaga aggaaccaag ttaactattt ttgaaaaagg
    18181 acaaaaccgt gtccaaccca caacagtttt catggtattt gaccaaaaag attatgaaaa
    18241 tatgactggt caaaaactgt ctctatcagg aaatgaggtc ggtctctttg ccaaaaatga
    18301 cggactgaaa ggacagaaag ctctaactct aaatgatcat caattttctg tcaaagaaga
    18361 atttaataaa gatttcattg tgaaccatgt tccaaataag tttaatatct tgactactga
    18421 ttacaattac cttgttgttc ctgatttaca agcctttttg gatcaattcc cagattcggc
    18481 tatctataat cagttttacg gtggtatgaa tgtaaatgtc agtgaagaag aacaactcaa
    18541 ggtcgctgag gagtatgaaa actacctcaa tcaatttaat gctcaattag acacagaagg
    18601 tagctatgtt tatggtagca atctagcaga tgctagttct cagatgagtg ccctctttgg
    18661 tggtgtcttc tttatcggta ttttcctatc cattatcttt atggtcggaa ctgttctggt
    18721 catctactac aaacaaattt ctgaaggcta cgaagaccgt gaacgcttta ttatcttgca
    18781 gaaagtcggt ttggaccaaa agcaaatcaa gcaaaccatc aacaaacagg ttttaactgt
    18841 tttcttcctt cctttgctct ttgccttcat acatctcgcc tttgcctacc atatgcttag
    18901 cctgatttta aaagtgattg gtgtactgga tacgactatg atgttgattg tgaccttgtc
    18961 tatctgcgct atcttcctca tcgcctatgt gctgattttc atgattactt caagaagtta
    19021 tcgcaagatt gtgcaaatgt aaaaaagata cctcgacttc aaaatcgagg tatttcttgt
    19081 attctaaatg ctgaaaagtt gtccgagcag gaaggtaact cccatggtca agagaccaat
    19141 agcaaggttc cgaatcatag ctgttttggt tggggctttt ccaagtctag cacttgtgta
    19201 accagtgaga agaagggcca caccgacaat aaggacggta gcagggatgc ggtaatcact
    19261 tggaaaaatg gtcactgaca gcattggagg caaacttcta aggaaaaagg caacgaagct
    19321 agaaatggca gcgtgccaag gattggtaaa ttcttcatac tcaatcccat atttttcctc
    19381 taccagagcc ttgagtggat ttttaagaaa gatcttattg gtcaagagtt gggcagaagt
    19441 tttgcattct ccattttgga tataagcagc atagagggat tttttggcta gttccctatc
    19501 ttggtctagc aagagttttt ctcgcgaaac ggcagcttcc tcggtatctt ttggagttga
    19561 aacggataca tattctccac cagccattga aaaggcacca gctaagatag ccgtaaaacc
    19621 tgataaaaag ataatccaga tattggtcgt ggcactggca actccgataa ccacaccagc
    19681 aatggaaata attccatcgt tagcatcaag aacacccgca cgcaggatat ttaaacgacc
    19741 tgcaaaattt gaatcaattt cgtgatttgt ttctgacgct aaatttcaag ttcaagttag
    19801 ccatcaagaa gtcttctctg ggtgacttgt agtccaagca ttttttagga tagttgttaa
    19861 tccacttttc gatgaatgcg acttctttgg gagtcatttt cttggttccc ttaggtaacc
    19921 atctacgaat gagcctgttg tgattctcat tagttcccct ttcccaagag gcatagggat
    19981 gtgcataata aatgtgctcc tcagaaaata cattagacaa gcgattgaat tccgttccat
    20041 tatctgccgt gatggaaaga atcttgtgtt gttttaagat gagttttaga gcctgattga
    20101 ccacatcagc acttttattt ggaatcaatc ggatgatctg atgtctactt tttcgatccg
    20161 tcaagacaag caagcagtag tttttcgctc tcgtaagtag aactgtatca atctcataat
    20221 gcccattctc caagcgaaaa ttgatagctt caagccgctg ttcgatggat tgaccagcag
    20281 gtttaaagtt ggtgctggcc tgtttcttaa gcgcttttcc ttttctaggg taaagcagat
    20341 cctgtttgct taaccccaat tttccatgat gaatccaata gtaaatggtt gaaattccca
    20401 cgttaacccc tttagccatc accatcattt caggcgaaaa tttttggtta tgatagtgga
    20461 gaatcttttc ctttagttcc ttggtcacgc ttgatctctt gaccgagtgc ttgcgattat
    20521 tttcataaaa ctgttgagca tagtcggcag aataaacctc tttgaagcgc ccttttccaa
    20581 gacattgtcg gactgtccta cgcttgattt cagtgtggat agtttgagga gcttttccaa
    20641 gtagagaggc aatttctcta tttgatttcc ctttgttcgc cttttgtagt ataatggttt
    20701 tgcatctctg tgcctttctt gtgtttgtgg ttgaacaaca agtata
//
LOCUS       DAVHSH010000032        20253 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000032 DAVHSH010000000
VERSION     DAVHSH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.032"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            120..275
                     /locus_tag="VVR08_001339"
                     /pseudo
     CDS             120..275
                     /locus_tag="VVR08_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            475..3750
                     /gene="rexB"
                     /locus_tag="VVR08_001340"
     CDS             475..3750
                     /gene="rexB"
                     /locus_tag="VVR08_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU6075248.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3747..7397
                     /gene="addA"
                     /locus_tag="VVR08_001341"
     CDS             3747..7397
                     /gene="addA"
                     /locus_tag="VVR08_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU6075249.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7612..8790
                     /locus_tag="VVR08_001342"
     CDS             7612..8790
                     /locus_tag="VVR08_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075250.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLMFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLGRLVI
                     "
     gene            8999..14836
                     /locus_tag="VVR08_001343"
     CDS             8999..14836
                     /locus_tag="VVR08_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6075251.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAVQPELPEAVVTDKGEPEVQPELPEAVVTDKGEPEVQPALPEAVVSDKGEPEQVAP
                     LPEYTRPQAGAVVEPAIQPELPEAVVTDKGEPAVQPELPEAVVTDKGETEVQPESPDT
                     VVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYT
                     GKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNK
                     YRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQ
                     HENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPD
                     DQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVSSKEDAA
                     TISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTVGY
                     EIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNV
                     NNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAISGDNFDNMKEDHA
                     YSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDADKVKEKKAELVSKHSTKVEDFDFTS
                     RYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRETIVKYGNLVDESSELFTKELLSVVP
                     MKNNEVITDINKNKQEINKLLLHFEGNKSQVLNIAYKNDFSKVAEYSIEYQGLLYTPN
                     TLLHDYSNIVDNVLTDLNSVQYDSNAIKKILDISDKVKNTELYLDEQFVKTKANIKDT
                     LSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALLLGLTYLERWYNFKYGETKAKDLV
                     MYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNVITYNVLLSKNYGTESLFKALEGY
                     RKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKKQSEQGTKYSIGIYDRLTSPSWKY
                     QSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSKVHPKGDNLNKFVEDNVREAAKR
                     FRDHYDYWYKILEPENREKLYRSLLVYDAFKFGRDNTEDKVTYQADFETDHPAIKYFF
                     GPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRS
                     GLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTRLQVADPTQRFNSAEDLHNY
                     MHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYKQDPDGNSVYATNVVRRLTM
                     DEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMG
                     RRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKIKSYGKEVGLVTDKLVLEKVFNN
                     RYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSWGRTNRITITSIANLQNMINTAVN
                     EDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTNDFRRSIFENKK"
     gene            14880..20117
                     /locus_tag="VVR08_001344"
     CDS             14880..20117
                     /locus_tag="VVR08_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6075252.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVSEDGERQIVT
                     SYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPVLTLTKVTEDAMNRSANLNY
                     ELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDWFKDYKIATTMIYDRG
                     QGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMY
                     LKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKP
                     HPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEG
                     KHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVT
                     GNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYV
                     DANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLS
                     HHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKE
                     HHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTKKEDEYKSTQDYKVDRDL
                     AYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMV
                     HYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASV
                     QLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADH
                     QLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSV
                     DLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDW
                     FIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYN
                     TMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRV
                     PTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNP
                     NNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTP
                     SSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHV
                     EADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSS
                     INDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKH
                     NAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKY
                     WYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVF
                     KALLKNTDGFFNPLFKKDI"
BASE COUNT         6960 a         3534 c         4142 g         5617 t
ORIGIN      
        1 gattgaaata agatacgaac agcttgatta gggaaatcaa attaatttct agaaatattt
       61 tagcatccac gatgtactat tatagtttca atttactata gttcaatcat tctatcaaga
      121 atattgaata tataaaggca cgtaatatta aaacttcttc tgatatcgaa ttagagtccg
      181 atgttgatgg cgataaatca gacaatctac ccgtcgacat taagatactg ggacaacaca
      241 ttgaagtgta ttccgtacct aagaaacaat cataaaactc aaagtcttgt taccgaggct
      301 tttttattat gtgattttca gtagccagac ttattctatc taatacaagt aaagctaagt
      361 atttaagatt tagcagatga tgaagaaaag aaaggatggc ctaaatattt taacagattt
      421 acgaggctaa tcatggtata atatagggtg atgaaaaatt ccaacgaggc tgagatgaaa
      481 ttactttata ctgatattcg aacttctttg acagaaattc taacaagaga ggcagaagag
      541 ctagttgcag ctggcaagcg ggtcttctac attgccccca actctctttc ttttgaaaag
      601 gaacgcgccg tgctggaatg cttgtcccag caggcttctt tttctattac cgtcacgcgc
      661 tttgctcaaa tggctcgtta tctggtcctg aatgatttac cagttaaaac tactcttgat
      721 gatatcggtc ttgggttggc cttttacaaa tgccttgccg aactcgatcc caaggacttg
      781 cgtgtttatg gcgctattaa gcaggatcct caattgatcc agcagttaat tgagctttac
      841 catgagatga ccaaatctca gatgagtttt ttggacttgg agaatttaac agatgaggat
      901 aagaggacgg atttactctt gatttttgag aaagtaacag cctatcttaa tcaaggtcag
      961 ttagcccagg gaagtcagtt gtcccatttg attgaggcta ttgagaatga caaggtaagt
     1021 agtgatttta atcaaatcac cttggtcatt gacggcttta ctcgtttttc tgctgaggaa
     1081 gagcgggttg tggacttact tcacggcaaa ggtgttgaga ttgttatcgg ggcttatgct
     1141 agtaagaaag cctataccag tccttttagc gagggcaatc tctaccaagc cagcgtaaaa
     1201 tttctccatc atctggcttc taaataccaa acgcctgctc aggactgttc tcaaactcat
     1261 gagaagatgg atagttttga caaggcttct cgtttgttgg agtcttctta tgacttttca
     1321 gaactcgctt tggatgtcga tgagaaagac cgtgaaaatt tacaaatctg gtcttgtttg
     1381 acgcaaaagg aggagttgga gctagtagcc cgtagcattc gtcagaaatt acatgagaac
     1441 tcagacctga gctacaagca ttttcgtatt ctcttggggg atgtagcttc ttaccagtta
     1501 tctctcaaaa ccatttttga ccagtatcag attccttttt atcttggtag aagcgaagcc
     1561 atggctcatc atcccttgac tcagtttgtc gagtctattt tagctttaaa acgttaccgt
     1621 tttcgtcagg aggatttgat taatcttctt agaactgatt tgtatactga cctcagtcag
     1681 tctgatattg atgcttttga gcaatatatc cgctatcttg gtatcaatgg cttgccagcc
     1741 tttcagcaaa tcttcaccaa atcccaccat ggaaaattta atcttgagcg tttgaatgtc
     1801 ctccgcctga gaattttagc acctcttgaa accctctttg ccagccgaaa acaaaaggct
     1861 gaaaacctcc tacaaaaatg gagtgtcttt ctaaaagaag gagctgtgac caagcagtta
     1921 caagatttga caaccacttt ggaagctgta gaacaggaaa gacaagccga agtttggaag
     1981 gctttctgcc atgttttaga acaatttgcg actgtttttg ctggttcaca ggttagtctg
     2041 gaagacttcc tagccttgct ccattctgga atgagtttgt cccaataccg taccattcca
     2101 gcaacagtgg acactgttct ggtgcagagt tacgatttga ttgcaccatt gactgctgac
     2161 tttgtctatg ctattggact aactcaggac aatttaccaa aaatttctca aaacaccagt
     2221 cttctgacag atgaagaaag gcaaaatcta aaccaagcga ccgaagaagg cgttcaatta
     2281 ctgattgcca gcagtgaaaa tctcaagaaa aatcgctaca ctatgctttc cttggtcaat
     2341 tctgctcgta agcagttgtt cttgtcggct ccaagccttt ttaacgaaag tgaaagtaag
     2401 gaatctgcct atcttcaaga gttgatccat tttggattta ggcggagaga gaagaggatg
     2461 aatcacaaag gactgtctaa ggaggatatg gggtcctatc acagtctttt gtctagtctg
     2521 gttgcctatc accagcaggg tgagatgagc gatactgagc aagatttgac ttttgtcaag
     2581 gttctgtcgc gtgtcatagg taaaaaacta gatctgcaag gtctggaaaa tccagctatc
     2641 ccaaccagtc caagcagcaa gaccttagcc aaggacacct tgcaagctct ctatcctgcc
     2701 aaacaggagt tttacctgtc tacgtcgggt ttgacagagt tttatcgcaa tgaatacagt
     2761 tatttcctac gctacgtttt aggcttgcag gaggaattac gtttgcgtcc tgatgcccgt
     2821 agtcacggga atttcttgca tcgtatcttt gaacgcgcct tacagttgcc taatgaagat
     2881 tcctttgacc aacgtctaga acaagctatt caagaaacca gtcaagaacg cgaatttgaa
     2941 gctatttatc aagaaagttt ggaagcccag tttaccaagg aagttttgct tgatgttgca
     3001 cggacgactg gacatattct ccgacacaat ccagccatcg aaaccatcaa agaagaagca
     3061 aattttggtg gaaaagacca agcctttatt caattagaca atggacgcag tgtctttgta
     3121 cgaggcaagg tggaccggat tgaccgtttg aaagctaatg gagcgatagg agtagtagac
     3181 tacaaatcca gtctgactca gttccagttt cctcatttct ttaatgggct caattctcag
     3241 ttaccaacct atcttgctgc cctaaaaaga gaaggggagc agaacttttt cggcgccatg
     3301 tacttggaaa tggctgaacc tgtccaatct ctgatggcgg taaaaagtct ggcaggagca
     3361 gtggtagaag ccagcaaatc tatgaaatac caagggctct tcttggaaaa agaaagcagt
     3421 tatttaggcg aattttataa caaaaacaag gctaatcaac tgacagatga ggaatttcag
     3481 ctcctactgg actacaatgc ctatctttac aagaaagctg ctgagaagat tttagcaggc
     3541 cggttcgcca tcaatcctta tactgaaaat ggcagaagca ttgccccata cgtccagcaa
     3601 catcaggcta ttacaggctt tgaagccaat taccatctgg gccaagcccg tttcctagaa
     3661 aagttggacc tagctgatgg caagcgtctg gtcggagaaa aactcaagca agcttggttt
     3721 gaaaaaataa gagaggagtt aaatcgatga agcttattcc ctttttaagt gaggaggaga
     3781 ttcaaaaact gcaagaagca gaagcaaatt cgagcaagga acagaagaaa actgccgaac
     3841 aaatcgaagc tatctacact tctggtcaga atatcctggt ctcagcatcg gctggttctg
     3901 gaaagacctt tgtcatggta gagcgcattc tggaccaatt ggcgcgtggt gtcgaaattt
     3961 ctcaactctt tatctcaacc tttaccgtca aggctgcaac tgaacttaaa gaacgtttag
     4021 agaaaaaaat cagcaagaaa atccaagaaa cagatgatgt cgatctcaaa caacacttgg
     4081 gtcgccagtt ggcagaccta cccaacgctg ccatcggaac catggactct ttcacacaaa
     4141 aattccttgg caaacatggt tatctgcttg atattgcacc taatttccgt attttacaaa
     4201 accaaagcga gcaacttctt ctcgaaaacg aagtctttca tgaggtcttt gaagcgcatt
     4261 accaaggtaa acagaaagag agctttagtc atttgctgaa aaactttgct gggcgtggca
     4321 aggacgaacg gggtctgcgg cagcaagtct ataaaatcta tgacttcctc caatccacca
     4381 gtaatcctca aaagtggctg agtgaatctt tcctcaaagg ctttgagaaa gctgatttta
     4441 ccagtgaaaa agaaaaactg actgagcaaa tcaaacaagc cctctgggat ttggaaagct
     4501 ttttccgtta ccatctggat aacgatgcca aggagtttgc aaaggctgcc tatttagaaa
     4561 atgttcagtt aattctggat gaaattggct ccctaaatca ggagttcgat agtcaggctt
     4621 atcaggcagt acttgcgcgt gttgtcgcca tctctaagga gaaaaacggt cgagctctga
     4681 ctaatgccag ccgtaaggct gatttgaagc ccctggctga tgcctacaac gaagagagaa
     4741 agacccagtt tactaaacta ggacaattat cagaccagat agcgattctc gactatcaag
     4801 aacgttatca tggagacact tggaaactag ctaaaacctt ccaatctttc atgagcgatt
     4861 ttgtagaggc ttatcgtcag agaaaacgac aggaaaatgc ctttgaattc gctgatatca
     4921 gccattacac cattgagatt ttagaaaatt tcccacaagt tcgtgagtct tatcaggagc
     4981 gcttccatga agtcatggtc gatgagtatc aggatatcaa ccatattcaa gaacggatgc
     5041 tggaattgtt gtctaatggc cacaatcgct ttatggtggg agatatcaag caatccatct
     5101 atcgtttccg tcaggcagac ccgcagattt tcaatgagaa attccaacgc tatgcgcaaa
     5161 atcctcaaga aggcaagctc attctcctca aggaaaattt ccgtagtagt tcagaagtgc
     5221 tgtcagcaac caatgatgtc tttgaacgtc tcatggacca agaggtcggc gaaatcaact
     5281 atgataacat gcaccagctt gtttttgcca ataccaaact gactcccaat ccagacaaca
     5341 aggccgaatt tctcctctac gacaaggacg atacaggtga ggaagaagag agtcaaacag
     5401 aaacgaaact aacaggcgaa atgcgcttag ttatcaagga gatccttaaa cttcatcagg
     5461 aaaaaggtgt tgcctttaag gaaattgccc ttctgacctc tagtcgtaat cgtaatgacc
     5521 aaattctact tgccctgtct gagtacggga ttcctgtcaa aactgacgga gagcaaaaca
     5581 attatctcca atccctagaa gtgcaagtca tgctagacac ccttcgtgtc attcacaatc
     5641 ccctgcaaga ctacgccttg gttgccctta tgaagtctcc aatgtttggt tttgatgagg
     5701 atgagctagc acgtttgtcc cttcagaaag cagaggataa agcccacgaa aatctctatg
     5761 agaaactagt caatgcacaa aaaaaggcaa gtagtcaaaa aggcttgatt cacacagctc
     5821 tagctgaaaa actaaagcaa ttcatggata tcctagcttc ttggcgcttg tatgccaaac
     5881 cccactctct ctatgacttg atttggaaga tttacaacga ccgtttttat tatgactatg
     5941 ttggggcttt gccgaatggt cctgctaggc aggccaatct ctatgcccta gcactgcgtg
     6001 ctgatcaatt tgaaaagagc aatttcaaag gtttgtcgcg ttttattcgt atgattgacc
     6061 aagtcttaga agcccagcac gatttggcaa gcgtggccgt cgcaccgcca aaagatgcag
     6121 tagagctcat gaccatccac aagagtaaag ggctggagtt tccttacgtc tttatcctca
     6181 atatggatca agatttcaac aaacaagact ctatgtcaga agtcattctc agtcgtcaga
     6241 atggtcttgg tgtcaaatat attgccaaga tggagacagg ggcagtagaa gaccactatc
     6301 ctaaaaccat caaactctcc attcctagtc tgacctatag gcagaacgaa gaggaattac
     6361 agctagcaag ctattctgag cagatgcgtt tgctgtatgt tgctatgacg cgggctgaga
     6421 aaaagctcta tcttgtcggc aagggttctc gtgaaaagct ggaatccaag gaatacccag
     6481 cagccaaaaa tgggaaacta aatagcaata ctagactgca agcacggaat ttccaagatt
     6541 ggctttgggc tatcagtaaa gtgtttacta aggacaagct caactttagt tatcgtttta
     6601 ttggcgaaga tcagttgacc agagaagcta tcggagagtt ggaaaccaag agtcctctcc
     6661 aagatagctc ccaagcagac aatcgtcagt cagataccat caaagaagct ctggaaatgc
     6721 tgaaggaggt ggaagtttat aatactcttc accgcgcagc tattgaactt cctagtgttc
     6781 aaaccccaag tcaaatcaag aaattctacg aaccagttat ggatatggaa ggtgtcgaga
     6841 ttgctggtca aggtcagtca gtaggcaaga aaatcagctt cgatttgcca gatttttcaa
     6901 ccaaagaaaa ggtaactgga gctgagattg gtagtgctac tcacgaactc atgcagagaa
     6961 ttgacctcag ccagcaacta acccttgcta gcctaacaga aacactcaaa caagttcaaa
     7021 ctagccaagc tgtcagagac aagatcaatc ttgataaaat tcttgctttc tttgacacag
     7081 cactcggtca ggaaattttt gctaataccg accatctcta tcgcgagcaa cctttctcca
     7141 tgctcaaacg agaccaaaag agtcaggaag actttgttgt ccgtggtatc cttgatggct
     7201 atctgcttta cgaaaacaaa attgttttgt tcgactacaa gacagaccgc tatgatgaac
     7261 caagtcaact cgtagaccgc tatcgtggtc agttagctct atacgaagag gctttatcac
     7321 gagcctattc gattgaaaat attgaaaaat acttgatttt actcggtaaa gacgaggttc
     7381 aagttgtaaa agtataactt atactcttcg aaaatctctt caaaccacgt cagcttcgcc
     7441 ttgctgtata tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
     7501 gagctgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcggct
     7561 agctttctag tttgctcttt gatttttatt gagtattaga aaggagacct catgacactt
     7621 ccagttagaa aatccctgca cgatgcagtt ttacaggctt cgaaagcgga tacttgggaa
     7681 caagctacca aggaatggaa tgaagtttcc ttgatgttta acggtatcgg ccgtagcaat
     7741 tgtgtctgtg gaaatgccat caaatacgct tatgaactct ttaacggtgt cacaggccaa
     7801 cgcctctttc caattggtag cgactgtgtt cgtcattttc atcgattgtc ccttgaccag
     7861 caattggaag aggaagaaaa actgctcaga aaggttgaaa atctaaccag aaaagctcag
     7921 aaaaaggaaa aaatcaaggt caataaaagt gactttgacg agcgacttct aaaatggctc
     7981 tgggaaaaag gtgttttcaa acccaatcgt ggcaatcaat ttgcgcctga gagagactac
     8041 cagcttttcc tagaagtctt tcagggagga agttggacca aggcggaacc aaagaaaaag
     8101 gctcggatgg aagaagtcct tgaaaagtgt atcaaaccct ttttacttgg gaaatcggat
     8161 gaccaactct accttgtcaa gctaggcaag gagaaaattg actacgaaca agaactccgt
     8221 atccaggcag agaaagaacg caagaagagg gataaaatcg ccaagcaata tgcagataat
     8281 ctggttctag ccatgggacc cgcagagcgt gcttatcaag attactttgg ctttacagag
     8341 accctgactc aagaagaacg caagtgggaa aaaattcttt ttggtaaaaa tagagcagaa
     8401 cgggctatca aggccaaaca ataccaaaaa gagctggaaa aagaccaacg aattgccagt
     8461 caggatccaa ttgaaagaaa acagaagcag acttggctcc tcaattccta ttttcgagag
     8521 cttcctgaag aaaaagctcg attttctagg ctcttattag aatatcgaaa aagtggtgaa
     8581 gtaccctttt caactgaata cctgtcagat catctcatcg actttttcta taaaatgaaa
     8641 gcctttgaat ttgaaatcgc accagaacaa gtccgagatt ttctaaaaaa aagcctgcag
     8701 gaagaccatc gctcatcagc acaaggaagc tggatagaag gaattctcct caactgcctc
     8761 aaaccatttt taggacgatt agtgatatga gtaacaccta ccgtgtaaat ttcatggtag
     8821 gtgttattgt accccaaaat aatataaaac aaagtatgaa agcgcatctc aattttaaga
     8881 cttttttgta aattaagagt ataattaagg tatactgcct tttctataga taatagataa
     8941 tacactaata taataaaggt ctttgtaaca tatataaatt ttatttcaag gaggaataat
     9001 ggaaaagtat tttggtgaaa aacaagagcg tttttcattt agaaaattat cagtaggact
     9061 tgtatctgca acgatttcaa gtttattttt tatgtctgta ttagctagtt catctgtgga
     9121 tgctcaagaa actgcgggag ttcactataa atatgtggca gattcagagc tatcatcaga
     9181 agaaaagaag cagcttgtct atgatattcc gacatacgtg gagaatgatg atgaaactta
     9241 ttatcttgtt tataagttaa attctcaaaa tcaactggcg gaattaccaa atactggaag
     9301 caagaatgag aggcaagccc tagttgctgg tgctagctta gctgctctgg gaattttaat
     9361 ttttgctgtt tccaagaaaa aggttaagaa taaaacggta ttacatttag tattggttgc
     9421 gggaatagga aatggtgtct tagtttcagt ccatgcttta gaaaatcatc ttttgctaaa
     9481 ttacaatacg gactatgaat tgacctctgg agaaaaatta cctcttccta aagagatttc
     9541 aggttacact tatattggat atatcaaaga gggaaaaacg acttctgatt ttgaagtaag
     9601 taatcaagaa aaatcagcag ccactcctac aaaacaacaa aaggtggatt ataatgttac
     9661 accaaatttt gtagaccatc catcaacagt acaagctatt caggaacaaa cacctgtttc
     9721 ttcaactaag ccgacagaag ttcaagtagt tgaaaaacct ttctctactg aattaatcaa
     9781 tccaagaaaa gaagagaaac aatcttcaga ttctcaagaa caattagccg aacataagaa
     9841 tctagaaacg aagaaagagg agaagatttc tccaaaagaa aagactgggg taaatacatt
     9901 aaatccacag gatgaagttt tatcaggtca attgaacaaa cctgaactct tatatcgtga
     9961 ggaaactata gagacaaaaa tagattttca agaagaaatt caagaaaatc ctgatttagc
    10021 tgaaggaact gtaagagtaa aacaagaagg taaattaggt aagaaagttg aaatcgtcag
    10081 aatattctct gtaaacaagg aagaagtttc gcgagaaatt gtttcgactt caacgactgc
    10141 gcctattcca agaatagtcg aaaaaggtac taaaaaaact caagttataa aggaacaacc
    10201 tgagactggt gtagaacata aggacgtaca gtctggagct attgttgaac ccgcaattca
    10261 gcctgagttg ccagaagctg tagtaagtga taaaggcgta ccagaagttc aaccagcgtt
    10321 accggaagca gtcgtaaccg acaaaggtga gcccgctgtc caacctgaat tacccgaagc
    10381 tgttgtaact gacaaaggcg agcctgaagt tcaacctgaa ttacccgaag ctgttgtaac
    10441 tgacaaaggc gagcctgaag ttcaaccagc gttacccgaa gcggttgtaa gtgataaagg
    10501 tgaaccagag caggtagccc cattgccaga atatacaaga ccacaagcag gtgcagtagt
    10561 tgaacctgca atccaaccag agttaccaga agctgttgta actgacaaag gagaaccagc
    10621 agtccaacca gagctaccgg aagcggttgt aactgacaaa ggtgagactg aggttcaacc
    10681 agagtcgcca gatactgtgg taagtgataa aggtgaacct aaacaggtag caccgcttcc
    10741 agaatataca ggaccacaag ccagcgctat tgttgaacca gagcaagtag caccactacc
    10801 agaatacaca ggggtacaag ccggatcgat agtcgagcca gagaaagtag aagcaccgaa
    10861 agaatatact ggtaaaatcg aacaacctag tgcagaagat actaaacctg aaaatgaggc
    10921 aagctctaca aatggggaat cggaacgtcc taaagataaa attaaagaag aaaaacaagt
    10981 cgacaagaaa ctagaactta gaaatgtttc aaacgtggaa ttatatacgg tagaaaataa
    11041 taaatatcga catattacgg ctgtagatgg tgctttagat agttcattga agtatttcat
    11101 gaaggtaaaa tcagaaaatt ttaaagatat aatgttgcct gttactaaaa ttgaaagtac
    11161 aacaaaaaac aataaagaag tatacaaaat tgtggctcat gcagaaaatc taattcaaca
    11221 cgaaaacaat gttatttcga atgactatac atattattta ccaaaaactc agcaaagtga
    11281 aactggcgtc tatacatcat ttaaaaattt agttgatgca atgaatagtg accctaatgg
    11341 aacattccat ttaggtgcaa ctatggatgc tcgtgaagtt gaacttccgg atgatcaaga
    11401 aagttatgta aaaaatgaat tttacggaaa attaataggt gaaaataatg gtaagtatta
    11461 tgctatttat aacttgaaaa aacctttatt taaaactcta aacaccgcta ctattcagaa
    11521 tctttcaata aaagaagcga atgtttcttc taaagaagat gctgctacaa tatcgaaaga
    11581 agcaaaatac aatactctta tagataatgt tcattctgat ggtattatag ctggtgaacg
    11641 tggaattggt ggattggttt caaaagtaga taactcgaga atttctaata gtagttttac
    11701 aggcagaata actaacacat atgatacaac tgtagggtat gaaattggtg gtttagtagg
    11761 taaactttct ggttcgcttg cttctataga gaaatcaata gcatcgattg acatagcctc
    11821 taatgcaaaa tcaggagatc aaattgttgg tggtatagcc ggagttgttg agaaaagtgc
    11881 gacaattaag tatagctatg ttgaaggaaa tgttaacaat gtgcgacact ttggtaaagt
    11941 tgggggagtt gcaggtaatc tttgggatag agattcacaa gatgtaagta aatcaggtaa
    12001 actatcatat gttttaagtg atgttaatgt aacaaatggt aatgctatat cgggtgataa
    12061 ttttgataat atgaaagaag atcatgctta tagtagtaaa ggcaataaag tagtaaatgt
    12121 agtccaagta gatgatgaac ttgtgactaa agattcagat gtacaaagag gtacggtatt
    12181 agatgctgat aaagtaaaag agaaaaaggc agaattggtt tccaaacaca gcactaaagt
    12241 agaagatttt gatttcactt caagatacac tactatttac aatgaagtaa caggttatca
    12301 aaagtcgaga gaacaagtat ataaaaatat tgaaaaacta ttaccgttct ataatcgaga
    12361 gacaattgtt aaatatggta atttagtaga tgaaagcagc gagctattta ctaaagaact
    12421 tctatcagtt gttcctatga agaataatga agtaataact gatattaata aaaataaaca
    12481 agaaataaac aaattgttat tacattttga aggtaataaa tcacaagtat taaatattgc
    12541 atataagaat gatttctcta aagttgctga gtatagtata gagtatcaag gattattata
    12601 tactcccaat actctattgc atgactacag taatattgta gataatgttt taactgactt
    12661 gaattctgta caatatgatt caaatgcaat taagaaaata ttagatatct cagataaagt
    12721 taaaaatacg gaattatact tagatgagca atttgttaaa acaaaagcaa atataaaaga
    12781 tactttatca aaacttctgt cagcggatgc agcaatcgct gagaatagta attcgataat
    12841 tgataattat gttattcaga aaatcaaaca gaataaagaa gctttattgt taggattaac
    12901 atacttagag cgttggtaca attttaaata tggtgaaacg aaagcaaaag atttagttat
    12961 gtatcacttg gatttcttcg gtaaatctaa tagttctgca ttagataatg ttattcaatt
    13021 aggtaaatct ggatttaaca atttactagc aaaaaataat gtaattactt acaatgtatt
    13081 attatctaaa aattatggaa ctgaaagttt atttaaagca ttagaaggat atagaaaagt
    13141 attcttacca acaacttcta acaatgagtg gtttaaagct caaactaaag catatattgt
    13201 tgaagaaaaa tcttctattc cagaagtaag taaaaaacaa tcagaacaag gaactaagta
    13261 ttctatagga atttatgata gattaactag tccgtcatgg aaatatcaaa gtatggtctt
    13321 accactatta actttacctg aagaaaaaac agtatttatg atagcgaata tttcaacaat
    13381 aggatttggt gcttatgata gatatagaag taaagtccat cctaaaggag ataacttaaa
    13441 taaatttgta gaagacaatg taagagaagc tgcaaaaaga tttagagatc attatgatta
    13501 ttggtataaa atattagagc ctgagaatag agagaaactt tatagaagtt tattagtata
    13561 cgatgcattt aaatttggtc gagataatac tgaagataaa gtaacttatc aagctgattt
    13621 tgaaactgat catccagcta taaaatactt ctttggacct gcggggaata atgttgttca
    13681 taatggacac ggagcatatg ctaccggaga tgcattctat tatatggcat atcgtatgtt
    13741 ggataaagat ggagctgtaa catatactca tgaaatgaca cataactctg atagagaaat
    13801 ttatcttgga ggatatggaa gaagaagcgg attagggcct gagttttatg ctaagggctt
    13861 attacaagca cctgaccacc catatgatcc aacaataaca attaactctg tgttgaaata
    13921 tgatgattca gaaaattcaa caagacttca agtagctgat ccaactcaac gatttaatag
    13981 tgcagaagac ctacataatt atatgcataa tatgtttgat ttaatatata ctcttgaaat
    14041 attagaaggt cgtgctgtag ctaaattaga ttataatgcg aaaaatgatt tattaagaaa
    14101 aattgagaat aaatataagc aagatccaga tggtaattct gtttatgcga caaatgttgt
    14161 tcgcagatta acgatggatg aagttaataa attaaattct tttgatagtt taattgaaaa
    14221 tgatattatt actagcagag ggtacaaaga ccaagaatat aagagaaatg gttattatac
    14281 aattgattta ttttcaccga tttattcagc tcttagtgga gagaaaggga ctcctggtga
    14341 tttaatggga cgtcgtatag cattcgaatt attagctgca aaaggatata aagagggcat
    14401 ggtaccttat atctcaaatc aatatgaaaa agatgcaaaa gctgcgggaa gtaagattaa
    14461 atcttatggt aaagaagtag gtttagttac agataaatta gtacttgaaa aggtatttaa
    14521 taatcgttac tcatcttggg tagaatttaa aaaagcaatg tataatgagc gaatagctaa
    14581 atttaataat ctaataagtg ttagctttaa taatccaaat gtaagttggg gaagaactaa
    14641 tagaataaca ataactagca tagccaacct tcaaaatatg ataaatacgg ctgtcaatga
    14701 agatgctgaa gattttagag cacaattata ccctgataca aatagtagag ttcttaaact
    14761 gaaaaaagca atatataaag cctatcttga ccaaacaaat gattttagaa gatcaatttt
    14821 tgagaataaa aaatagtgtt tactattagg aaataaaaag tgaatgtgga ggattagaat
    14881 tgtcattatt aaaaaaagat aaattttcca ttaggaaaat aaagggtatt gttggttcga
    14941 tattcttggg gagtttttta tttgcactgt cagttgttgg tgtatcgact tatcattact
    15001 tagattatag tactttgaca caaactgaac gtgatcaact caaacaaggt agacctgatg
    15061 aatcaaaaga gtcatatgct ttggtttatg aaaaagacgc attaccaaac acaggaagtt
    15121 ctcaatctat tatgactgta ttgggtttgt tagctatcgg gagtcttatt gtgattatca
    15181 caaaagataa aaagaggaaa aaaatagcta catttttgat tgtaggggcg acaggtttag
    15241 ttacactatc aactgcttca gcacttaatt tgaatgctaa catccatgag tctggacgtg
    15301 atggtgtgtt gcaaatttct ggttacagat atgttggtta cttggagctt gatgatagaa
    15361 ctgtttcgtc ggtttctcca gcatcaactg tttctccagt tgagcaaccc aaagttgtga
    15421 ccgacaaagg cgaaccagaa gttcagccag cgttaccaga agcagttgta actgaaaaag
    15481 gggaaccaga agtacaacca gccttacccg aagcagttgt aactgaaaaa ggggaaccag
    15541 aagttcatga gaagcctgac tatacgcaac caataggtgc aaaccttgtt gagcctgaag
    15601 ttcatgagaa actagcatac actgaacctg taggtacaac aggagtagat gaaaatggaa
    15661 acttgattga gccacctgtt aacgatattc cagagtatac tgaaccaata tctacagttt
    15721 cagaagttgc atcagaaaga gaagagttgc cttctttaca taccgatatt cgtacagaga
    15781 ctattcctaa aaccactata gaagaatctg atcctagcaa atttataggc gataattctg
    15841 ttaaacaagt tagtgaggat ggcgaacgtc aaattgttac tagctatgaa gagttacatg
    15901 gcaaaaaaat cagcgagtca gttgaaacag taacaatttt gaaagaaatg aagcctgaaa
    15961 ttattgtaaa aggtacaaaa gaaaaaacgg ctcctgtttt aaccttgacc aaagtaacag
    16021 aagatgctat gaatcgttct gccaacttaa attatgagct tgataataaa gataatgctg
    16081 aaatatcaag tattgtagct gaaattaaag atggtgatac agtagttaaa agggttgatt
    16141 tatctaaaga aaaattaact gacgctgtac aaaatttgga ttggtttaaa gattataaga
    16201 ttgcaacaac aatgatttat gatcgtggtc aaggttctga aacgtctaaa ctggatgaaa
    16261 gacctctgcg tttggagttg aaaaaggtcg aaattaaaaa tatcgcatct actaatttag
    16321 tgaaggtaaa tgatgatggt actgaaacac ctagtgattt tatgaatgaa aaaccttcag
    16381 aagaagatgt taaaaaaatg tacttaaaaa tcactagtcg cgataataag gtaactcgtt
    16441 taactgtaga ctctattgaa gaagtgactg aagaaggtca aaaactttac aaaataactg
    16501 ctgaagcaca agatttgatt caacacacag acccaacgaa ggttcgtaat aagtatgttt
    16561 attatataga aaaaccccat cctaaagaag ataatgtcta ctataacttt aaagatttag
    16621 tagatgctat gaatactgat aaaaatggta catttaaact tggtgcagat ttgaatgcca
    16681 ctggtgttcc aacacctaag aaatggtatg ttgacggcga ctttagaggt acattgaaga
    16741 gtgtagaggg gaaacattat actatccaca acacggagcg tccgttattc cagaatatta
    16801 ttggtggtac agtaaccaaa gtaaatctgg gaaatgtaaa tatcaatatg ccatgggcag
    16861 accgcatcgc accgattgct gacactatta aaggtggcgc taaaattgaa gatgtcaaag
    16921 tgactggtaa cgtattaggt agaaactggg tatctggatt tattgataag attgacaacc
    16981 aaggtacact cagaaatgta gcctttatcg gaaatgtgac atctgtaggt gatggtggtc
    17041 aattcttgac cggtatcgtt ggtgagaact ggaaaggact agtcgaacgt gcgtatgttg
    17101 acgcaaatct tattggcaag aaagccaagg ctgctggtat tgcttattgg acacaaaaca
    17161 gtggtgacaa tcataaagtt ggtgtcgaag gtgcagtcaa gaaaggaatt gtgaagggta
    17221 ccattcaggt agaaagtcct gttgaagtcg gcggtgctgt tggacgtttg agtcatcatg
    17281 gttatatcgg ggaagtcgta tctatgatga aagttaagaa gggtgaaatt ttttatggtt
    17341 ctagtgatat gaatgatgac ccatattggg tggcgaataa tgtacgagga aattatgtcg
    17401 ttaatggtgt gagtgaaggt acgatatctt atgctcgtgc taaagaacac catcgtatca
    17461 aaccaatttc acagtcagaa gcagatacta aaattatgat gttaggtatt acagcacaag
    17521 attttgctat caacgaacct gtggtcaatc gcttaaaccg tttaaccaaa aaagaagatg
    17581 aatataagtc aacccaagac tataaagtag atcgagatct ggcttatcgt aatattgaga
    17641 aacttcaacc attttataac aaagaatgga ttgtcaacca aggtaacaaa cttgcagaag
    17701 attcaaactt agctaagaaa gaagtccttt ctgttacggg tatgaaggat ggacagtttg
    17761 taactgactt atcagatatt gataagatta tggttcacta tgctgatggt actaaagaag
    17821 aaatggacgt cactaagaat gctgattcta aagtgaaaca agttcgtgaa tataccatcg
    17881 ctggacaaaa cgttgtttat acaccaaata tggttgagaa agaccgtaac caattgattc
    17941 aagatatcaa agataagttg gcgtcagttc aattgatttc tcctgaagta cgtgctttga
    18001 tggatgcacg taagaaacca gaagaaaata ctgatgaacg taagaatggt tatattaaag
    18061 acctttactt agaagaaagc tttgctgaaa cgaaagctaa tcttgataaa ttggttaaat
    18121 ccttagttga aaatgcagat catcaattaa atagtgacga aacggctatg aaagcacttg
    18181 ttaagaaggt ggatgaaaat aaagctaaaa tcatgatggc tctgacttat ctcaatcgtt
    18241 actatgatat caagtatggg gatatgacta tcaagaactt gatgatgttt aaacctgatt
    18301 tctatggtaa atcagttgac cttcttgatt tcttgattcg aattggatca agtgagagaa
    18361 atatcaaagg tgacagaact ttggatgctt atcgtgatat gattggtgga actattggta
    18421 agtctgaatt acatggattc ttagattaca atatgcgtct cttcactaac gatactgatt
    18481 taaatgattg gttcatccat gcagctaaga atgtatatgt atcagaacct caaacaacga
    18541 acccagattt tgttaataaa cgacatcgtg catttgatgg tttgaacaac ggtgttcata
    18601 atcgtatgat tctacctcta ttaactctta agaatgcaca tatgttcttg atttcaactt
    18661 acaatacaat ggcttatagt tcttttgaga aatatggtaa gtatacagaa gaagctagaa
    18721 atgaattcaa aaaagaaatt gataaggttg cacatgctca acaaacatac ttagacttct
    18781 ggtcacgttt agcattgcca agcgtacgtg accaattact caagagtgag aatagggtac
    18841 caactcctgt gtgggataac caaaactata gtggtattaa aggaataaac cgtatgggtt
    18901 atgatgagaa gaaagtacca attgcgccaa ttcgtgagtt atatggtcca acttggaaat
    18961 tccataatac caactggaat atgggagcta tggcatctat tttcccaaat cctaataaca
    19021 atgaccaagt ttatttcatg ggaacaaata tgattagtcc gtttggtatt tcagccttta
    19081 ctcatgaaac tacacacgtt aatgatagaa tgctttactt cggtggtcat agacaccgtc
    19141 aaggtacaga cgtcgaagcc tatgctcaag gtatgctaca aactccgtca agtattggtc
    19201 accaaggtga atatggtgct ttaggtttga acatggctta tcatcgtgaa aatgatggtg
    19261 accaatggta taactatgac cctgataagc ttcaaactcg tgaagatatc gatcgatata
    19321 tgaaaaacta taatgaagca ctgatgatgc tagatcatgt agaagcagac gccgtacttc
    19381 cacaattgaa tggtgataat agcaagtggt tcaagaaaat tgatagagaa atgcgcagaa
    19441 atcttgggga tggtttgaat aacttagtag caccgcacca atgggacaac gttcgtgact
    19501 taaatcaaga agagagttct aagaaattat caagtattaa cgatttgatt gataataatt
    19561 tcatgaccaa acacggaaat ccaggtaacg gacgttatag accagaggat tttagaccaa
    19621 actcagctta cgtaaatgtc aatatgatgg caggaattta cggtgggaat acgagtcaag
    19681 gtgctcctgg ttcattatcg ttcaaacata atgccttccg tatgtggggt tattatggat
    19741 atgacaaagg tttcactagt tatgtatcta gcaaatatca aggtgaagct gataaacaaa
    19801 accagggtag attaggtgat gatttcatta tcaaaaaagt ttcaaacaac caattctcaa
    19861 atcttgaaga ttggaagaaa tattggtatc atgatgtgaa atccagagct gaaaaaggat
    19921 tcacagagat tacaattgat ggacaaacca ttcacaacta taatgaactg aaagacttat
    19981 tcgacaaagc tgtcacagaa gacctcaaga aagctggaaa ctactcaaat actgagaatt
    20041 tgaaatccaa agtcttcaaa gctcttctta aaaacacaga cggtttcttt aatccattgt
    20101 tcaaaaaaga catttaaacc ccaattattc accccaaatc taaaaaccat ccagaatcct
    20161 tgccttagct tagatcctgg atggtttctt tttcacccaa tgggtgtttt ttactagaca
    20221 aaaaagagtt tcccctttat ggtataagtg tag
//
LOCUS       DAVHSH010000033        20190 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000033 DAVHSH010000000
VERSION     DAVHSH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.033"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..494)
                     /locus_tag="VVR08_001345"
     CDS             complement(<1..494)
                     /locus_tag="VVR08_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU6075253.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPKNLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKI"
     gene            complement(721..1590)
                     /gene="rsmI"
                     /locus_tag="VVR08_001346"
     CDS             complement(721..1590)
                     /gene="rsmI"
                     /locus_tag="VVR08_001346"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU6075254.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1593..1910)
                     /gene="yabA"
                     /locus_tag="VVR08_001347"
     CDS             complement(1593..1910)
                     /gene="yabA"
                     /locus_tag="VVR08_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU6075255.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1950..2840)
                     /locus_tag="VVR08_001348"
     CDS             complement(1950..2840)
                     /locus_tag="VVR08_001348"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU6075256.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2837..3475)
                     /locus_tag="VVR08_001349"
     CDS             complement(2837..3475)
                     /locus_tag="VVR08_001349"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU6075257.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(3695..4492)
                     /gene="proC"
                     /locus_tag="VVR08_001350"
     CDS             complement(3695..4492)
                     /gene="proC"
                     /locus_tag="VVR08_001350"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU6075258.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIVGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(4496..5758)
                     /locus_tag="VVR08_001351"
     CDS             complement(4496..5758)
                     /locus_tag="VVR08_001351"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU6075259.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQVLLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADDDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(5768..6898)
                     /locus_tag="VVR08_001352"
     CDS             complement(5768..6898)
                     /locus_tag="VVR08_001352"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU6075260.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6978..8861)
                     /gene="cbpE"
                     /locus_tag="VVR08_001353"
                     /gene_synonym="pce"
     CDS             complement(6978..8861)
                     /gene="cbpE"
                     /locus_tag="VVR08_001353"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU6075261.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENRMEIGWVNTGGQSYYLSKDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(8864..9751)
                     /locus_tag="VVR08_001354"
     CDS             complement(8864..9751)
                     /locus_tag="VVR08_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6075262.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9741..10202)
                     /locus_tag="VVR08_001355"
     CDS             complement(9741..10202)
                     /locus_tag="VVR08_001355"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU6075263.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10199..11107)
                     /locus_tag="VVR08_001356"
     CDS             complement(10199..11107)
                     /locus_tag="VVR08_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6075264.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11100..11297
                     /locus_tag="VVR08_001357"
     CDS             11100..11297
                     /locus_tag="VVR08_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075265.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(11349..12020)
                     /locus_tag="VVR08_001358"
     CDS             complement(11349..12020)
                     /locus_tag="VVR08_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075266.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12074..12295)
                     /locus_tag="VVR08_001359"
     CDS             complement(12074..12295)
                     /locus_tag="VVR08_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU6075267.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            12633..13586
                     /locus_tag="VVR08_001360"
     CDS             12633..13586
                     /locus_tag="VVR08_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU6075268.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            13813..14622
                     /locus_tag="VVR08_001361"
     CDS             13813..14622
                     /locus_tag="VVR08_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6075269.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14803..15678)
                     /gene="aguB"
                     /locus_tag="VVR08_001362"
     CDS             complement(14803..15678)
                     /gene="aguB"
                     /locus_tag="VVR08_001362"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU6075270.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15688..16773)
                     /gene="aguA"
                     /locus_tag="VVR08_001363"
     CDS             complement(15688..16773)
                     /gene="aguA"
                     /locus_tag="VVR08_001363"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU6075271.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16770..17897)
                     /gene="nspC"
                     /locus_tag="VVR08_001364"
     CDS             complement(16770..17897)
                     /gene="nspC"
                     /locus_tag="VVR08_001364"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU6075272.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17897..19156)
                     /locus_tag="VVR08_001365"
     CDS             complement(17897..19156)
                     /locus_tag="VVR08_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU6075273.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(19153..20013)
                     /gene="speE"
                     /locus_tag="VVR08_001366"
     CDS             complement(19153..20013)
                     /gene="speE"
                     /locus_tag="VVR08_001366"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU6075274.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5918 a         4610 c         3683 g         5979 t
ORIGIN      
        1 ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat ttacatgaat aaacttatac
       61 acttcccaag tcgctgtttt agtcgcttca tcagcccact ttctcatatg cggttcaaat
      121 aattcttcct cactcaacga atcaatcatt gcagagatag aattaatatt ttcatttaat
      181 tttgctttca actcttgcag agataaatga gcgtaggtat ctgtgaacca ctgatataat
      241 tcaccaagtt gattccattt aaatttatcc gatggtgttt ttacttgaag cccctttctt
      301 tcatcttctt cccatttaag aaccaagttg gtccaaccaa cctgataagc aaggttttct
      361 gctggagttc tgtcaacttc atcagctctc ttatctttta aattttttgg aatattatca
      421 aattctaaaa tatatttctc aaatgttttc tctatctcag cttttagttc ttctttattt
      481 tcgtatgttc gcaaaaaatc accttctttc tgatttatca atcctttgat ttaaaatgac
      541 cttatttttc tatttatacc ttctaagaac gctataactg ctgctccaac catcggtatt
      601 ccgtatgggc ttaataaaaa acttaatacc aaagcttcta taccaagtga tacatcttta
      661 tattatcatc actaattaag ttaaacagaa acagacagaa ttattacatc ctgtctccct
      721 ttattgtttt tcttcccagt cgtggtaggc agcgtagagt tgactcttat tccactggta
      781 aatcttagct acttccttaa tagcttgatt tttcttcata ccttgctgga tacgagcttg
      841 gatttctaag aacaagtctt cctcgtcttt ttcttccaca tcctgactgg caccttcaac
      901 aatcagaaga cattcaccct tgagagacgt ttcagagatg ctttccagca attcagaaat
      961 tgtacctctt tggtattctt catagatttt ggtcaattcc ctgaccaaga caacggagcg
     1021 gtcaccgtag acttctagca tattttccaa tgtatctgcc acacgatggg gcgattcata
     1081 aaaaatctga gtttcaggat agtctttttt cgagtcgaaa aattgctttt gctggcctga
     1141 ttttctcggt aaaaagccgt aaaagatatg tggctgcggc gctaaaccac tggcaatcaa
     1201 ggcggaaatt cctgcagagg cacctggaac tgtaacaact gcaatttctt cctcaatagc
     1261 tgccttaacc aaatcatgac cagggtctga aatgctaggc aaaccggcat cagagacctg
     1321 agcaatactt tgccctgctt tcaagaaacc aatcaaatca ggaatttttt ccttggcatt
     1381 gtgctcatga aaactgatct gcttggtgga aatgtcaaaa tgcttgagca aaagacctgt
     1441 attgcgcgta tcctcagcag caatccagtc cacttctttc aaggtctgga tagcacgaaa
     1501 agtcatatca tctagattgc caatcggcgt tgccactaga tacagcttgc catagggaga
     1561 ctgcccctta aaactttttt gaatttgcat gcctactccc tgtataacaa ctcatcacaa
     1621 aacatacatt cttcgtcctg ctctcgacgt tgtccataaa aatcattaca tacgtgaaat
     1681 ccatcacggt aaatacgacg gacactttcg cgaacatgtt tggccttgac gggagcgtct
     1741 gcttccacct cacccaagcg ttctcgcaac ttactatttt ccaagcgaag agctgtattt
     1801 tcttctacca agctcttgag atttttcttg atggcttcca catcggctaa ggttaccaat
     1861 aattgttggg aaaaatcatc cagcgcgtca aataattctt ttttgtccat aaaacagccc
     1921 tttcctttct ttatcattca tttttgagtt tatatttctt tcaagaccag atattccatg
     1981 gcattttgaa agctgacatt agcttgccac atttttctag cttctagtaa atcttgtaga
     2041 atcactctta ctcttacctg caagaggtcc tgcccgcaga gaacttcaag aatccgtaaa
     2101 acctgatcct gtttttcctt atcatctgcc aagttggcta atttggcaac ctgtagataa
     2161 ctttcttttt tcttagctac taaccaagtc agcaggcgtt cactttcatc gaccaaggtc
     2221 caaaaacttg cctgattagc caacttttct gcttcagctc gcgattgact aaacttagct
     2281 aaaagagtcg cttttttctt aacaagtccc atttgttcta agagtaagat aagtttttct
     2341 tcttgctttt taaagtggaa gatctgagtc cgacttcgga ttgtcggtaa catcttttcc
     2401 tcatcgctag tcaagaagaa aatataaact tcactctggg gttcttcgat gaccttgagc
     2461 agagaattgg ctgcgttggg atgcatttta tccgcttgct cgataataaa gacctgttgc
     2521 tggctttcaa tccctgcttg agaaaactgt cccaccaatt ccctaatgcg ttctgtcttg
     2581 atgacctgat tgactggctt aatcaaggtg acatcgggaa attctccctg ttcaatcagc
     2641 ttgcaacttc ggcatttctc acatggtaag acgccaactt tatccgtaca aaagaggctc
     2701 ttagctaaaa attgcgctat ttccaagctt ccaaagaaac ctgaaaagag ataggcgtga
     2761 ttgagctggt cttgttctaa gatacggaca aaacggtcaa actgagctgg ttgccaagcc
     2821 tttagttgat cttgtttcat ttggccaagc ccattccgtc aaacaagaca gccttggtag
     2881 tttccacaac ttgctccaaa gggagactag catcaatctt gacaatgcga tttccctctt
     2941 tatccagaag agaaaggtag ccttgacgaa cttttttatg caagtccaac ccttccaaat
     3001 ccaaacgatt aacctcgcgg tcactattag cagcaatacg agccagccct tcttccacct
     3061 cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc tgtcgcaaac tgattgagcc
     3121 agtcaatggc ttcaatatct aagccacgac caaatccctg ataggcaaca gaactatcga
     3181 taaaacgatc catgatgacc aacttgccag cttcaagggc tggaagaact ttttccacca
     3241 aatgctgtct gcgactggca atatagagaa gtagctctgt tttagcatcc atctgagtat
     3301 gacttggatc caaaatcact tcccgaatct tctccccaat caagactccg ccaggttcac
     3361 gggtcgtcaa cacctctact cctttttcct ctaaaattgg tagcagagcc tctaaaacac
     3421 tggtcttgcc tgctccctct ggtccctcaa gagagactaa aaatcctttt gacatgtcta
     3481 actcatttct tttttactac ttctattcta tcaaaaaaat aggggtttgt gacaatcttt
     3541 ttgtcttctc atttcatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
     3601 ctgtacttga gtacggcaag gtgaagctga cgcagtttga atttgatttt cgaagagtat
     3661 caaccaccat aaaagaggca gataaaacta cctcttattt acctagttct tgtgttcgtt
     3721 tataggcttg atgaactgcc tccatgacta tgcctcgaaa agcatgcgct tctaagcttg
     3781 ctacgccaac aatagtcgaa ccgcctggac tacaaacttg atctttcaaa actccaggat
     3841 gttgctggct ttctaggacc aattgcccag ctcctaccac agtttgggct gccattttca
     3901 aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc tgccaaggcc tcaataaaga
     3961 gatagacaaa ggctggtcca caacctgcaa gacctgtcgc tgcattgatt aagctttctc
     4021 ctaattcaac caagagacca gccttggcta aaagctgaca aaagatctca ctgtcctcag
     4081 ccctgcaatt aggagacaag gcataactaa tcactccttg cccgatagaa gcaggggtat
     4141 taggcatcat acgaataatt cgatgttggc ttgggataag acttgctagt ttttctaagg
     4201 tcaatccagc tgccatcgaa atcaaaagaa gactttctct tttttcaagg atggtctggt
     4261 attgagaaag cagttcagaa aactgagcag gcttaacacc tagaaaaatc acatctgctt
     4321 cttcgaatat ttcttcattg ttagaagtct gaccaccgaa gttagcgatg aaagcatcca
     4381 ccttgacttg actacgattg gcaaggagaa tctcatctga cggtctagcc tgcaagacag
     4441 acttggctaa actagcaccc atattcccca aaccgataaa tccaatcttc atctcttact
     4501 cccttatctg tccatcacca gtgaccacat acttgtagct agtcaattcc ttcaagccca
     4561 tgggaccacg cgcgtgcaat ttctgagtag aaatccccat ttcacaacca agaccaaatt
     4621 gtcctccatc tgtgaaacga gttgaggcat taacatacac cgctgcagag tccacttgat
     4681 ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat agcatccgaa tgatgggtac
     4741 tgtgggattc aatatgcgca accgcttctt ctaaactgct cacaacctta acagctagaa
     4801 tatagtctaa aaactcggta tcaaagtctt gtgcttgagc agcttgacct gaaacaaact
     4861 ggcttgcttt gctatctagg cggaattgaa ttggttccaa cccagcttct tttcgatctg
     4921 caaccagcac ttgctccaag cgaggaagga agcttgctgc cttgtcttca tgaaccagca
     4981 gaacctccat ggcattgcag acagaaggac gactggtttt ggcattgttg atgatagaca
     5041 gtgccttgtc gtcatctgcg tccttatcga cataaacatg gacaatccca gttcctgtct
     5101 cgataacagg cacaatggca ttctcaacta ctgcattaat caagccagct cctccacgag
     5161 gaatgagaag gtctagatag cccttggcct tcatcatagc ataactactt tcacggctag
     5221 tatcctccac cagttgaatc acatttggat gaatagtagt cgtctccaag cccttcttca
     5281 aggctgtgac aatggcatgg gttgtttgat aggcatcctt accactacga agaacaaccg
     5341 catttccact cttaagagtc aaagcagccg catcagacgt cacatttgga cggctttcat
     5401 agataatacc gatgaccccc atagctacac gtttttttgt gataaccaaa ccattttcaa
     5461 gctgacttgt ttctaaaact tcaccgattg gatctggtaa ggcaaccact tcacgaattc
     5521 ctcttgccat cgcttctata cgatctgcat ccaaataaag acgatccaac atcacatctg
     5581 agattttccc cttagccgct gccatatcga gggcattagc cgctaaaatt tcctcagtag
     5641 cagccactaa gtgatcagcc atggctagca agacttggtt tttcacttct tcactagctg
     5701 tgttaatcga ttttttaaca gcctgtacct gttcaaattg ttcttgtcta ctcaccatag
     5761 tttacctcta aaattctgta aaaagtagtt ggatttcagg agtaatggaa atccagtcgt
     5821 cacggtaaat caagacaccc ttggcttttt gagaacgcaa catatcctcc aaagcagatg
     5881 ctccaaattg cacgcgtcct tttccaagtg attttccact ttccttgtca aatactgtca
     5941 cgatatcacc gtaagaaaag actccttctg cttcaacgat accagataag agaagactct
     6001 ttccatgttg agagagagct tccgcagccc ctttatcaac ccaaatagaa ccttgactct
     6061 gagcatagaa ggcaagccat tgtttctggg tacgaagccc cttctcttga gcaacaaagt
     6121 aagaaccatc ctcggtctcc tctgccgcct caatcatgga atctgatttc aaggatgagc
     6181 agatataaac aggaactcct gattccgtcg cgatagttgc agccttgatt ttggttaaca
     6241 tacccccagt tccgtttgac gaaccagctc caccagccat atcaataatc tcacgattga
     6301 tggtctcgat tctctccaag cgtttggctc ttggatctga attaggattt ccagtataga
     6361 gaccgtccac atctgtcaag agaaccaaaa ggtctgcttg gaccatcgcc gctacttggg
     6421 cacttagagt gtcattgtcc ccaaccttga gctcatcaat aacgacacta tcattctcat
     6481 tgatgatagg aattgcccca cggttgagca aaaccgacaa agcctgatgg gcatttttat
     6541 aacgacgctt atccacaaag tcatcttggg tcagcaagat ttgtgcagaa acgatttgac
     6601 gcaagagaag attggtcgta tattcttcca acaaaagtcc ctgccctacc gctgctgaag
     6661 cctgtttatc agcaatctta gtcggacgct ttttaaatcc taaggctcca aaaccagccg
     6721 caatggcacc tgaagacacc aaaatcaact catgaccagc ctcgtgcagc atagccaact
     6781 gctgggtaat atcctttacc ttactacgtg ataaacttcc atcctcattt gtcagagaag
     6841 aagtacccac cttaaagaca atccgtttgt atttcatagt ctcactccga ttattcatat
     6901 ttatccatta taacatgaat aacaggaaat agaaaagagt tgataggaaa aagaaggccc
     6961 taaaaccttc ttttctacta ctgttctgat tccgatttgt ttacactcgt ttcagagctt
     7021 tgtgaagttg aggatgtcaa atcttgacta gttgaagaat ttgtaacact ttcatgttga
     7081 ctcgtttctt tattttcaag atcctttttc actacttctt tggattcttt tatttctgaa
     7141 tgacttgtag ttttaattgt agcagatttc tcgatcggaa catccactaa ccaggcacca
     7201 cttgaatcca cagtatagcc ttctggtgtc ttaccattca caagtaattg accattttct
     7261 ttcaagaagt accatttatc cttgtcttta atccaaccta tagctcgtga accatctgtc
     7321 ttgtagaaat accaatcatt tgccttttta agccagcctt gcttcatagc tcctgattct
     7381 tctagatagt aatgatgtcc agcaacttct atctcacctg tcttcatgat accagtagaa
     7441 tccatatagt accaggcttc tttatctttt acccagcccg ttttcatttc ccctgatgga
     7501 gcaaagtaat accattgccc cttatattga agccaacctg tcttcataga accatccttt
     7561 gatagataat aggactgacc tccagtattt acccaaccaa tttccatccg gttttctttg
     7621 ttaaaataat accagattcc agcgattttc ttccaatttt tagcagcaac accagagtct
     7681 gtcaaataga accaacgatt gttccatttt ttccattgat tctgtaataa gatacccgtt
     7741 tggttaaagt aataccattc acccttaatt tcattccaac cgacagcata ttctcctgta
     7801 gaatcaggcg cttgatacca ccagtttcca tatgaactct tatgccaacc agcttgaaaa
     7861 cttggaatag gcttgtagga agttgaaatg tttactaaac cgtcttttcg aatatcaaaa
     7921 actgtcgcat catagtcttt gctggctgcg ttgattctct caattcctcg ttctttgagc
     7981 caattaacat actcactatc aacaccattt ttccaaggta gactatccga agtttgaaca
     8041 atcaaactcg gactcaaatt tttaatgaaa tccttggtat ttgatttgtt ggtatcatgg
     8101 tgatgattaa acttcatcaa atcaactttt ccaatgagag gaccatactt gtcttctgct
     8161 ccatgaacat tatctaaatc gcccccaagg taaattttct tgccattgac tttcaccacg
     8221 ctaatcaagg aattggaatt gtcatcccaa attttcttta attcacccga tgaatcagtt
     8281 tcattttcat aattatagag ctgaatatcc atgtccccaa actgaaaatg agcatcccct
     8341 tgtgtgatat tttgaataac tgaaacacct gtttctgcag cagtctgtaa aaccttatca
     8401 tagccataca gattatccca tagacgttca gaattagtaa tacgactatc actatatttc
     8461 ttaagataga ctcggtcaac tggataggta gacagtaatt catcaacatt tccaatatga
     8521 tcactgtggg tatgggtcac caaaataaaa tcaagttttt ggacacccaa ttccttcaaa
     8581 cgacgaaaga cacggtctgt tagaacatgc ttataagacg tttcaattcc ttctctccat
     8641 ggatagcgag aatcacttcc atctgggaaa tcataatctt ctcctgtatc caccatggca
     8701 aaatgtccat tgctttcaag aataatcgca tcactgccac cttcttgaac attgataaag
     8761 tggattttat ttcctgaact ttcttgagcc tgaacattcc cataccatga caaacctaaa
     8821 aaagcgccta caagtgctaa actagttaat ttctttttca ttcttacttt ctcaatctct
     8881 ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa ttccaaggtc ttacctgttc
     8941 tcggatgagt aaaacctaaa gtcttggcat gaagaaattg tccatgtcct ttcaaagtct
     9001 tgcgaggacc atagacttca tcaccagcga ctggatggcc aatataagcc atgtgaacac
     9061 ggatttgatg ggtacgccct gtctccagtt gcaactccac taagctataa tcaccaaagc
     9121 gttccaagac gtggaaacgg gttactgcag gctttccttt agcagtcaca gcctgtttct
     9181 tacgatcttt ttcactacgg ccaatcggcg cttcaatcac accacgatca ttaggcagat
     9241 ttccatgaac aatcgcccaa tatttgcgaa gagacttttt atccttgagt tcttgagcaa
     9301 gtgctagatg cgcatcatcg tttttagcaa tcatgagaag acctgacgta tccttatcaa
     9361 tacggtgaac aatccctgga cgcagaaccc cattgatacc cgacaagtcc ttaatatgat
     9421 acatgagggc atttactagg gttccactgg tatgaccagc actcgggtgc acaaccattc
     9481 cctgaggttt gttaacgaca gccacatcct catcttggta gactatttct agcggaagat
     9541 cctcagccac atactctaat acctctggtt ctggcacatg gtaagtgacg acatcaccct
     9601 cttggactgt gtatttagct ttcttgactt gaccattgac caagacctgg cctgatttaa
     9661 tttgttcatt cgcgagacta cgtgataatt ctgacaaatc tgacaaagcc ttatccaaac
     9721 gcagaccacc agtttcaatt ttaatttcca tttatttcct cttttagcat tgcaatcaat
     9781 aaaataatca ctccaaccgt cagatagcta tctgccacat tgaaaattgc aaagttgata
     9841 aagtcaaggt ggaacatatc cacaacaaag ccctgactga ccctgtcaat aaagtttcca
     9901 agaccacccg cgattattag agtcaaaccc aagaccatcc agaatgagtc ctccatgtgt
     9961 ttatgtaaat accaaatggc acctatcacg acaaccagag taatgacagc gaataacaac
    10021 tgctgatctt gtaagataga aaaggctgca cctcgatttt gcaggtaggt caagctaacg
    10081 aaattgggga tccaggagcg cacttcaccc agtggaatct gctggacgat ataggatttg
    10141 accaactgat ccagcccaat caaaagcagt acaatgactg ccactattgc tctttttttc
    10201 atgatttcct cttttgatca aaatattctt gcatgacttc tacgaagaga gtcccagctt
    10261 gactaagctc cacttcttca cgtttaacat agaccatgcg gttatctagg ttatccttga
    10321 gacgaataac tgtaatgcca ttaacactgt cactatctaa aaatccagaa cctgtcgcat
    10381 aggcgtccgt ccgctccaaa ataccattca aggtggcacg gtctgtcaca ttaaacatct
    10441 gtgagctagc gctggtatca acaaagttct ctgaataata aaggtactcg tctttctctt
    10501 gagtgaaacg aaccgttggt aaatccgcta aatcctccat gactaattcc tctttctggg
    10561 ctaaaggatg accctcacag agataaatat gggtatggaa aggaatcaat tcgatgacct
    10621 ccagacctaa cttttcaacc cgttgcataa tccccttttt attttgattg ttgaggtaga
    10681 taatcccaat ctcactatgc ccttgcgcca cttcatctaa tatttgaaca gtagttgatt
    10741 caaaaatacg gaagttctta tagtcaggat agcgctctga aaaggccgta atagttggtg
    10801 gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc tttttcttct tcaggattgg
    10861 catactgatt ttgaaaaata tcaaatcctt taaccaattc ttgcgctttt tcataaaatt
    10921 ccatcccacg acgggtcaag aaagtccctg agctggtccg acggaaaatc ttaaagccca
    10981 actctttttc caaatcacga acagaaatag acagactcgg ctgactaaca tacatctttt
    11041 cagcagcttc acgaaaagta ccactattgg caatagccac aacatagcgt aattgttgaa
    11101 tgttcatctt ctacccccaa cttctttatc ttttcattat accatatttt agaagttttc
    11161 caaaaaggaa aaaagaacat cctattcttc ttaactatct tcactatctg cctttctcac
    11221 gccaatctta ttttcaaaat caattcaaaa aaataagtgg ctacacacca cttcagtatc
    11281 ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc cggaaaattc cgacattttt
    11341 ttagtaagct aacttcctga aaataggagt aaccaaacat cccagaaggc agtgatattg
    11401 atgagaatat gaactagtat tggatagtag agatttttag tcatgcgata caatagagct
    11461 aaaataagac ctccactagc ataaatgaaa aaagcaagag gagttaaagc aaaattgata
    11521 tgaatataac cgaaaataat agcagaaagc aaaacatctc cgtaccaagg cgagtttttg
    11581 aaaaaggttg tcataagcac accgcgataa atcaattcct cagcaatagg ggcgatgaag
    11641 caaacgatga gcaagaaata agggaactcc tgtcgtccca tcatttctat cgtttcattc
    11701 aaagaaattt gatttgaagg cggggatatg aaatacgaaa agagaaagtc agacatatac
    11761 gaaatgatgt agcccagtaa aaggtagatg aagtacctca gctgccactt gaaatgaaaa
    11821 attttctttc ctgcaaaaac cagtagatag atgaccgcta agaaaagaac tccgctctcc
    11881 atcaaaagca gaatctgaaa aaattcacga cttgctggta gatagggctt tgcgaggtga
    11941 ttgaaaactc tccaaaacca agttgatttg taaaaaatta aggacaatgc tagtaaaatt
    12001 tgaatagccc gttttttcat attaaattct ctgctttctc cccttgtttc ttcatattac
    12061 taataaattt tacttaaaat ctcgcagcac ttcctttgca aagatgattg cctcctccaa
    12121 tatatcctaa atcataggtg cctctgggac aaaatccatg aaccggcaga gttaatactg
    12181 gttctatttc ccaatcgtac ctaccattag gatttttacc atatgaatct gctccacctt
    12241 gtatcagctc taattcttca tttgttagat ttatattttt tgtcattaaa atcatgatat
    12301 atttcctcca ttattcttca gattagttga gtaatctgat actcatacct acttacaaaa
    12361 aaactattat atttgaaagt tctataatga agttagccac cttaccttag tcaagaatta
    12421 gatgtttcac tatgtttgag taagttgatg atttcatttg ataacaggtt tgaaactgtt
    12481 aggctaggtg gccaaggcta atcatagcct tggtttagct gaaaaaacag gttcaagggt
    12541 tcctgttgtc aaatgaaatg tgatttaagg tataagaaaa cacctctgtg ctatacttgt
    12601 tgttcaccac aaacacaagg aaaggcacag agatgcaaga acattatacc ccaaaaggga
    12661 aacatttgac aatagataac cgtcgcttga ttgagcggtg gaagaatgaa aataagtcca
    12721 atcgtgaaat tgcaggcttg ttaggaaagg cgcctcaaac gattcatact gaagtcaaaa
    12781 gaggtacaac tttacaacaa gtgagaaaag ggctatacaa aaaggtctat tctgccgatt
    12841 acgcacaaac tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta attttaacaa
    12901 aggaaatcag agagaagatc ttacactatc ataagcaaaa attttcgcct gaaatgatgg
    12961 ttaacaagaa gcaagtgaaa gttggtattt caaccatcta ctactggttt cataatggtc
    13021 atttaggatt gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt gtcaagaagc
    13081 aagctagtcc gaactttaag ccggcaggta aatctatcga agaacgtcct gacgttatta
    13141 atcttcgctt ggaaaatggt cattatgaaa ttgataccgt cctactgact aagataaaaa
    13201 attattgcct gttagtctta accgaccggc ggagcagaca ccaaattata aggttaattc
    13261 caaataaaac tgctgaatct gtcaatcagg cgcttacgtt actattaggg gagcatcgta
    13321 ttctgtccat tactgcagat aatggttcgg agttcaaacg attgtctgag gtatttcctg
    13381 aggaacatat ctactacgca catgcttact cttcatggga gagaggttca aatgaaaatc
    13441 ataatcgatt aattcggaga tggttaccta aaggaaccaa gaaaacgact ccgaaagaag
    13501 tagcttttat cgaaaattgg attaacaact accctaaaaa atgcttggac tacaagtcgc
    13561 caagtgaatt tcttttgggt ggctaacttc aacttgaaat ttgggaaaac tattatatta
    13621 agttggtttt ttaatttgtc tagttgcaac attgacaaac atagtatagc atatctttgc
    13681 caaatatcct cttcaaatca tgaattgtca tcaaaacatc ttaaactata aaatcaatta
    13741 gtctcaagct ttctatcaat ttcttctcca aaatatgcta taataatagc aaaagataaa
    13801 gaaggaagac ctatgattaa actactagcc ttggatatgg acggcaccct cctcaatgaa
    13861 gccaaggaaa tcccacaagc tcacattact gctattcaca aagccattga aaaaggtgtc
    13921 aaactggttc tctgtacggg tcgccccctt ttcggtgtcc tcccctacta caaaaaactg
    13981 ggactcgacc tccagaatga gtatgtgatt gttaacaacg gttgttcaac tcaccagact
    14041 agcgactggg gcttggttga ctggcaagaa cttagtccag ctgacatcga atacctctat
    14101 gaccttgctg aaaagagtga tgttcagttg acactttttg acgagtcaca ttattttgtt
    14161 ctcggtggaa agcccaatca agttattgaa aatgatgcta aactagtatt ttcagacctg
    14221 actgaaattt ctcttgagga agcgactagt ggaaagttcc ggatgttcca aggtatgttt
    14281 ttaggaacaa aagaacaaac agacgatttt gagcagcgtt ttgctgaaga gctttgccaa
    14341 cgattcagtg gagttcgttc gcagcctgtc atttatgaag caatgccgct tggaacgaca
    14401 aaggctactg ctctttcacg actagctgag attttgaaga ttgattcctc agagattatg
    14461 gccatgggcg atgctaataa cgatatcgaa atgctccagt ttgcagggct tgggattgca
    14521 atgggaaatg ccagcgatta tgtcaaatct cttgcggatg ccgttacctc aagcaacgaa
    14581 gaagacggcg ttgcgcgtgc tattgagaaa tatattctat aaaaaagaaa agcaaataga
    14641 cagaagttac tgctatttgc ttttttgcta atattttaaa atacggacta atcaatagac
    14701 aagaatagcg aatcataaaa atcgatttac tagatgccat agtatcttat agttgctaat
    14761 aagaagttag tctagcagaa tgaatctctc atttctccca cactaatctg taatttgtct
    14821 atacatttct ggtcttctat ctcgaaacaa gccccagttt agacgttcac ttgctccctt
    14881 gtctaggtca taagtagcta acagaacagc ttcttcttgt ctttcagctc gttctagaat
    14941 agctcctgtt tcatccgtca taaaggagga accgtagaag tcaagactgg aactctgtcc
    15001 gccattttcc tcactaggag taacctcctc taaaccataa cgattggctg cgatgactgg
    15061 aacaatattc gctgctgcgt gcccttgcat agtacgttgc cagtgaccac aactatctgt
    15121 atccaaaatt ggctctgaac cgatagctgt aggataaaag agcaattcag caccattcaa
    15181 tgcaagacag cgggctgttt cagggaacca ttgatcccaa cagataccga taccaatctt
    15241 agcatagcga gtattccaga ccttgaaacc agtgttacca ggcgtgaaat agaatttttc
    15301 ttgataataa tggtcatctg gtatatgggt ctttcgataa acgcccagca cttccccatc
    15361 tgcatcaatg acggcaatag agttatacaa gacattacca tctttttcat agaaactgat
    15421 tggtaaaaca acttgtagtt ccttagcaat caccttaaaa tgctgaatgg cagtattttc
    15481 cgctacagat tgggcatact ggtagtagtc atactgacgt tcctgacaga aatagggatg
    15541 ttcaaacaac tcgggcaaga gaataatttg ggctccttgc tcagcagcct gacgtactaa
    15601 acgctctgcg gtttggatat ttgttgccac atccttagcg cattgcatct gaatggttgc
    15661 aactcttaca tttctcatct ttttctccta ttctggaatt tgttgggtga tacagtggat
    15721 attgccacca cctaagagaa tatctctggc tggtattccg acaactttac ggtctgggaa
    15781 acacttgctg aggatatcta aggccacttg gtcgtttaca tcctcaaact gtggaaccaa
    15841 gacagccttg ttggcgatat aaaagtttac gtaggaagct gctagtcgtt cacctgcgta
    15901 tcgctcttct tctccttctt catagatgta gcctggcaaa tcttcttctg tcacaacttg
    15961 tcgaactgca gggataggca atttatgaat ggtgaagtga caaccttttg catctgtttc
    16021 ctgttctaag agttcgagat ctgcttttga catggcatac tggggatcat tttcgtcatc
    16081 tgtccaagcc aaaacaacct cagcaggacc aacaaaggca gcaacattat cgacgtgttc
    16141 attggtttca tcctgataaa taccataagg aagccaaata actttttcag caccaagact
    16201 ttctaataat gtgttttcaa tctcctcttt agtcaagtta ggattgcgac caggactaag
    16261 caagcaactt tcagttacga gaatagttcc ttgaccatcg ctatggattg cgcctccttc
    16321 cagtacaaaa ggtttagcat catagacagg cctttccaag gcctcagcaa aacgactggc
    16381 tacttggtca tcctcttcat aatcttgata aagaccatca taggtgcctc cccaagcatt
    16441 gaaggcccaa tccacggcta atttcttacc tttgtcattg acgagaatgg ttgggccagt
    16501 atcacgcgcc caggcatcat tggtgggaat gtctaaataa acaaccttgt ctccaagata
    16561 ggattgggct tcagatagat aggcctgctc caccaaaaga tagactcttt ccccttctgc
    16621 tatagtctcg atgatctgag taaatgctct tttagcatcc tttccttgaa aaggccatga
    16681 tcctggtcga gtcggccata tcatgagggt accatgatgg ggttcgtact ctgctggcat
    16741 gtgatagcct aatttttttg gactgtccat catgataatc tccctttaaa gtcttgatag
    16801 ccaaaagctt tgagtaagct acagtctccc tgttcgtcca tgagatagag acttggcaat
    16861 ccaataccat taaaggtatt atttttgaca aaagaataaa tggccatgtc ttgaaaataa
    16921 agtctgtctc cgatttggac tggattttca aaactataat caccaatcac atcgcccgtc
    16981 agacaggtat tagaagaaag tctgtaggta tgggcttttt cctgtgcctc aaagccattt
    17041 ctcaaaggtg gacgataggg catctcaagt acatcaggca tatggcaggt cgcagaggcg
    17101 tctaaaacca agatttccat accgttttct acaatatcta atacctcagt tgctaaataa
    17161 cccgcattaa gcgcaatggc ttcaccaggc tcgatataga tttcaagatt gtaagttttt
    17221 cggatacgct tgatttctga aatcagcaaa tccacatcgt aaccttctct tgtaatatga
    17281 tgaccaccac ccatattgag ccattttacc tcatgtaagt agggaccaaa ctgttcttct
    17341 actgctttca aagttgtttg taaatcatct gctccctgct cgcaaagggt atgaaaatga
    17401 agtccgtcaa ccaaatctag caaatcactc ggaatcttgt ctatagtaac tccaaagcga
    17461 gaacctggtg cacaagggtc atagagcgcg tgatctcctt gagttgaaca ctgagggttg
    17521 aggcgcaaac caacactgac accagcctct cgacaacgcg aaccatgctt acgcaactgt
    17581 ctctctgagt taaagacgat atggtctgtt atcccaagca attcctccat gtcctcatcc
    17641 ttgaaagctg gtgcaaaaac atggacttca ccaggaaatt cttcccttgc caatttggcc
    17701 tcatagagtc cactagctgt cgtacctgat agatactggc taatcaaggg ataagttttg
    17761 tagagggaat atgccttctg ggcaagcaag accttgcaac cggcctcttc ttgtacatat
    17821 tgtagaatgc ggcaattagc ttctaacttg gccaagtcaa taacataggc tggtgttggt
    17881 acttgttcta acttcattag tccaccattt gtggattttc aaccacaacc catggcaaac
    17941 catactcatt caaagcttcc atgaatggat ctggatctaa ctcctcaagg ttatacactc
    18001 cagcttgttt ccaagttccg ttcatgacta attttgtccc aatcatggct ggaactcctg
    18061 tcgtataaga aatagcttgc gaaccaacct ctgcgtaaca ttcctgatgg tcgcagacat
    18121 tgtagatata gatagtcttt ttgacaccgt ctttgacacc tgtaaagata catccaatat
    18181 tggttttacc tacagtacgt ggaccaaggc tagcaggatc tggaagcaag gctttcaaaa
    18241 attgaattgg aacaatttct tggccgttaa agttaatggt atccgtacga aggagtccaa
    18301 cattttcaag acatttcatg tgcgtcaagt aagattgacc aaaagtcata aagaaacgaa
    18361 tgcgtttgac acctggaatg ttcttggcca atgattcgat ttcttcatgg tgaaggagat
    18421 acatatcttt ttgtccaact tgagggaaat catactcacg cttgatagac atagcttcga
    18481 cttcgaccca tttcccatct tcccagtaag aacctggcgc agaaacctca cggagattaa
    18541 tttctggatt aaagttggtt gcaaatggat aaccgtggtc accgccatta cagtctaaaa
    18601 tgtcgatata atggatttca tcaaaatagt gtttgagggc ataagctgaa aagacactag
    18661 ttacacctgg gtcaaaacca gaaccaagaa gagcagtcaa gcctgcttct ttgaatttct
    18721 cttgataagc ccactgccat gagtagtcaa agtaggctgt aaaaccaagt tccttacaac
    18781 gtttttcgta gatagcacgc cactcagggt cttctgtgtc ttctgcttcg tagttggctg
    18841 tatcgatata gtgaacacct gttgccaaac aagcatccat aatggttaaa tcttgataag
    18901 gcagagctac attcaaaaca gcttctggtt tgtagctttc aatcagagca atcacttctt
    18961 caaccttgtc agcatcaaga gcagctgtct caatctttgt acttgttttg ccttccagtt
    19021 tagctttcaa gtcatcgcat tttgacttgg tacggctagc aatcataatc tctgtaaatg
    19081 tttcgctatc ttgacaaatc tttgaaatag caacttgggc aacgccccca caaccaataa
    19141 ctagtaaacg actcattttt ttccttcctc ttcttctaaa atgtcctcaa catacttggg
    19201 caacataaag gctcccacgt gtaagtttgc agtgtagtat tctgtgaaaa gctggcgttt
    19261 tttccagcct tccttgtcaa aatctttgac agggtggtat tttttcgatg caaatccaaa
    19321 caaccaatag ccagctgggc tagttggaat atgggcctga taaacccgac tgattggaaa
    19381 ggcttgattg accttgcggt gcatgcttcg gcaggccgac tcatcctcgt caaagaacgg
    19441 actcccatgc tggtaaatca tgatgccgtc ttccttcaga gctcgataac tattgccgta
    19501 gaattccttg gtaaagagtc cttccgtatg gccaaatgga tctgtcgcat cgttgatgat
    19561 aatatcatag tcatattcgc agtttcgcaa aaagcgtagc ccattttggt agtaaatggt
    19621 aacacgagga tcatctaggc ctgcagcaaa gtctgggaaa tactcacgac agacctcgac
    19681 caacatctca tccggttcca cgatatcgat ttgttccagt tcaggataga gtgttaatac
    19741 ttgggcaaca ccgccgtcac cacccccaat aaccaatact ttctttggat ttgggtggac
    19801 agccatggga acgtgaacgg tcatttcatt gtagacgaaa tcatccgcat ctgagaacaa
    19861 gacatggcca tttaaaatca gtattttccc aaaagctggc gtatccaaga cttcgatatc
    19921 ctgccattca ctttttccag cgtaaagttg cttggctgtt ctcagagaca atttgacatc
    19981 tggagtatga acttcagaaa accataaatc catctatttc tccttatatt atatttagcg
    20041 cagttagcta ctgccaaagc ccaagtggta tacttggaat aagccactgt ggattagttc
    20101 atttcctcca atcgcttgac gatttccgaa agggtctaac cacagctttt tgtttcaatt
    20161 ggtaatgagt ttgataacgc atagacgttt
//
LOCUS       DAVHSH010000034        18334 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000034 DAVHSH010000000
VERSION     DAVHSH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.034"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            88..5406
                     /locus_tag="VVR08_001367"
     CDS             88..5406
                     /locus_tag="VVR08_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6075275.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTVYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(5573..7732)
                     /locus_tag="VVR08_001368"
     CDS             complement(5573..7732)
                     /locus_tag="VVR08_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU6075276.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLRELSLPQLALLAGMPQAPNQYDP
                     YSHPEAALDRRNLVLSEMKGQGYISAEQYEKAINTPITDGLQSLKSVNSYPAYMDNYL
                     KEVIDQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSTMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVPAVETLNKVGLDRAKNFLN
                     GLGIDYPDMHYSNAISSNTTESNKQYGASSEKMAAAFAAFANGGIYHKPMYINKIVFS
                     DGSEKEFSDAGTRAMKETTAYMMTEMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(7729..8325)
                     /gene="recU"
                     /locus_tag="VVR08_001369"
     CDS             complement(7729..8325)
                     /gene="recU"
                     /locus_tag="VVR08_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU6075277.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            8391..8918
                     /locus_tag="VVR08_001370"
     CDS             8391..8918
                     /locus_tag="VVR08_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU6075278.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGRLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            8988..9317
                     /gene="gpsB"
                     /locus_tag="VVR08_001371"
     CDS             8988..9317
                     /gene="gpsB"
                     /locus_tag="VVR08_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU6075279.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            9338..9718
                     /gene="rnpB"
                     /locus_tag="VVR08_001372"
     ncRNA           9338..9718
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVR08_001372"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9803..10960
                     /locus_tag="VVR08_001373"
     CDS             9803..10960
                     /locus_tag="VVR08_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU6075280.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVHFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            10973..12367
                     /gene="mapZ"
                     /locus_tag="VVR08_001374"
     CDS             10973..12367
                     /gene="mapZ"
                     /locus_tag="VVR08_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU6075281.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     PASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            12443..13867
                     /gene="gndA"
                     /locus_tag="VVR08_001375"
     CDS             12443..13867
                     /gene="gndA"
                     /locus_tag="VVR08_001375"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU6075282.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKMLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            13879..14568
                     /locus_tag="VVR08_001376"
     CDS             13879..14568
                     /locus_tag="VVR08_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075283.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            14666..15685
                     /gene="cbpC"
                     /locus_tag="VVR08_001377"
     CDS             14666..15685
                     /gene="cbpC"
                     /locus_tag="VVR08_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU6075284.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGITWYYLDQPNGDMKTGWQYLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNTSNGDMTTGWFQVNGKWYYAYSSGALAVNTTVDGYYVNYN
                     GEWVR"
     gene            complement(15803..17035)
                     /locus_tag="VVR08_001378"
     CDS             complement(15803..17035)
                     /locus_tag="VVR08_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6075285.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKIGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(17564..17921)
                     /locus_tag="VVR08_001379"
                     /pseudo
     CDS             complement(17564..17921)
                     /locus_tag="VVR08_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
BASE COUNT         5685 a         3342 c         4127 g         5180 t
ORIGIN      
        1 ggttaagcat tgcattttca gaggaaggag tattttttaa aaaggaaatg taaacgcttg
       61 ctcaaaaatg aaaggattta gaagtttatg aataaaggat tatttgaaaa acgttgtaaa
      121 tatagtattc ggaaattttc attaggtgtt gcttctgtta tgattggagc tgcattcttt
      181 gggacaagtc cggttcttgc agatagcgtg cagtctggtt ccacggcgaa cttaccagct
      241 gatttagcta ctgctcttgc aacagcaaaa gagaatgatg ggcgtgattt tgaagcgcct
      301 aaggtgggag aagaccaagg ttctccagaa gttacagatg gacctaagac agaagaagaa
      361 ctattagcac ttgaaaaaga aaaaccggct gaagaaaaac caaaagagga taaacctgca
      421 gctgctaaac ctgaaacccc taagacggta acccctaaga cggtaactcc tgaatggcaa
      481 acggtagaga aaaaagaaca acagggaaca gtcactatcc gagaagaaaa aggtgtccgc
      541 tacaaccaac tatcctcaac tgctcaaaat gataacgcag gcaaaccagc cctgtttgaa
      601 aagaagggct tgaccgttga tgccaatgga aatgcaactg ttgatttaac cttcaaagaa
      661 gattctgaaa agggcaaatc acgctttggt gtcttcttga aatttaaaga taccaataat
      721 aatgtttttg tcggttatga caaggatggc tggttctggg aatacaaaac tccaggtaat
      781 agcacatggt ataaaggcaa ccgtgttgct gctcctgaaa caggatcaat aaaccgtctt
      841 tctatcactc tcaagtcaga cggtcagcta aatgccagca ataacgatgt caatctcttt
      901 gacacagtga ctctaccagc tgcggtcaat gaccatctta aaaatgagaa gaagattctt
      961 ctcaaggcgg gctcttatga cgatgagcga acagttgtta gcgttaaaac ggataaccaa
     1021 gagggggtaa aaacagagga tacccctgct gaaaaagaaa caggtcctga agttgatgat
     1081 agcaaggtga cttatgacac gattcagtct aaggtcctca aagcagtgat tgaccaagcc
     1141 ttccctcgtg tcaaggaata caccttgaat ggacatactt tgccaggaca ggtgcaacag
     1201 ttcaaccaag tctttatcaa taaccaccga atcacccctg aagtcactta taagaaaatc
     1261 aatgagacaa cagcagagta cttgatgaag cttcgcgatg atgctcactt aatcaatgcg
     1321 gaaatgacag tacgcttgca agttgtggac aatcaattgc actttgatgt gaccaagatt
     1381 gtcaaccaca atcaagtcac tccaggtcaa aagatcgatg acgaaagaaa actactttct
     1441 tctattagtt tcctcggcaa tgctttagtc tctgtttcta gtgatcaaac tggtgctaag
     1501 tttgatgggg caaccatgtc aaacaataca catgtcagcg gagatgatca tatcgatgta
     1561 accaatccaa tgaaggattt ggctaagggt tacatgtatg gatttgtttc tacagataag
     1621 cttgctgctg gtgtttggag taactctcaa aacagctatg gtggtggttc gaatgactgg
     1681 actcgtttga cagtttataa agaaacagtc ggaaatgcca actatgtagg aatccacagc
     1741 tctgaatggc aatgggaaaa agcttataag ggcattgttt tcccagaata cacgaaggaa
     1801 cttccaagtg ctaaggttgt tatcactgaa gatgccaatg cagacaagaa agttgattgg
     1861 caagatggtg ccattgctta tcgtagcatt atgaacaacc ctcaaggttg ggaaaaagtt
     1921 aaggatatca cagcttaccg tatcgcgatg aactttggtt ctcaagcaca aaatccattc
     1981 cttatgacct tggatggtat caagaaaatc aatctccaca cagatggtct tgggcaaggt
     2041 gttctcctta aaggatatgg tagtgaaggt catgactctg gtcacttgaa ctatgctgat
     2101 attggtaagc gtatcggtgg tgtcgaagac ttcaagaccc taattgagaa ggctaagaaa
     2161 tatggagctc atctaggtat ccatgttaac gcttcagaaa cttatcctga gtctaaatat
     2221 ttcaatgaaa aaattctccg taagaatcca gatggaagct atagctatgg ttggaactgg
     2281 ctagatcaag gtatcaacat tgatgctgcc tatgacctag ctcatggtcg tttggcacgt
     2341 tgggaagatt tgaagaaaaa acttggtgac ggtctcgact ttatctatgt ggacgtttgg
     2401 ggtaatggtc aatcaggtga taacggtgcc tgggctaccc acgttcttgc taaagaaatt
     2461 aacaaacaag gctggcgctt tgcgatcgag tggggccatg gtggtgagta cgactctacc
     2521 ttccatcact gggcagctga cttgacctac ggtggctaca ccaataaagg tatcaacagt
     2581 gccatcaccc gctttatccg taaccaccaa aaagatgctt gggtagggga ctacagaagt
     2641 tatggtggtg cagccaacta tccactgcta ggtggctaca gcatgaaaga ctttgaaggc
     2701 tggcaaggaa gaagtgacta caatggctat gtaactaact tatttgccca tgacgtcatg
     2761 accaagtact tccaacactt cactgtaagt aaatgggaaa atggtacacc ggtgactatg
     2821 accgataacg gtagcaccta taaatggact ccagaaatgc gagtggaatt ggtagatgct
     2881 aacaataata aagtagttgt aactcgtaag tcaaatgatg tcaatagtcc acaatatcgc
     2941 aaacgtacag taacgctcaa cggacgtgtc atccaagatg gttcagctta cttgactcct
     3001 tggaactggg atgcaaatgg taagaaactt tctactgata aggaaaagat gtactacttc
     3061 aatacgcagg ccggtgcaac aacttggacc cttccaagtg attgggcaaa gagcaaggtt
     3121 tacctttaca agctaactga ccaaggtaag acagaagagc aagaactaac tgtaaaagat
     3181 ggtaaaatta ccctagatct tctagcaaat caaccatacg ttctctatcg ttcgaaacaa
     3241 accaatcctg aaatgtcatg gagtgaaggc atgcacatct atgatcaagg atttaatagc
     3301 ggtaccttga aacactggac catttcaggc gatgcttcta aggcagaaat tgtcaagtct
     3361 caaggggcaa acgatatgct tcgtattcaa ggaaacaaag aaaaagttag tctcactcag
     3421 aaattaactg gtttgaaacc aaataccaag tatgccgttt atgtcggtgt cgataaccgt
     3481 agtaatgcca aggcgagcat cactgtaaac actggtgaaa aagaagtgac tacttatacc
     3541 aataagtctc tcgctctcaa ctatgttaag gcctacgccc acaatacacg tcgtgacaat
     3601 gctacagttg acaatacaag ttacttccaa aacatgtacg ccttctttac aactggatcg
     3661 gacgtatcaa atgttactct tactttaagt cgcgaagctg gtgatcaagc aacttacttt
     3721 gatgaaattc gtacctttga aaacaattca agcatgtacg gagaaaacca tgatacaggt
     3781 aaaggcacct tcaaacaaga ctttgaaaat gttgctcagg gtatcttccc attcgtagtg
     3841 ggtggtgtcg aaggtgttga agacaaccgc actcacttgt ctgaaaagca tgatccatat
     3901 acacaacgtg gttggaacgg taagaaagtt gatgatgtta tcgatggaaa ttggtcactc
     3961 aagaccaatg gactggttag ccgtcgtaac ttggtttacc aaaccatccc acaaaacttc
     4021 cgctttgaag ctggtaagac ctaccgtgta acctttgaat acgaagcagg ttcagacaat
     4081 acctatgctt ttgtagtcgg taagggagaa ttccagtcag gtcgtcgtgg cactcaagca
     4141 agcaacttag aaatgcatga attgccaaat acttggacag attccaagaa agccaagaag
     4201 gcaaccttcc tcgtgacagg tgcagaaaca ggagatactt gggtaggtat ctactcaact
     4261 ggaaatgcaa gtaatactcg tggtgattct ggtggaaatg ccaacttccg tggttataac
     4321 gacttcatga tggataatct tcaaatcgaa gaaattaccc taacaggtaa gatgttgaca
     4381 gaaaatgctc tgaagaacta cttgccaacg gttgccatga ctaactacac caaagagtct
     4441 atggatgctt tgaaagaggc ggtctttaac ctcagtcagg ccgatgatga tatcagtgtg
     4501 gaagaagcgc gtgcagagat tgccaagatt gaagctttga agaatgcttt ggttcagaag
     4561 aaaacggctt tggtagcaga tgactttgca agtcttacag ctcctgctca ggctcaagaa
     4621 ggtcttgcaa atgcctttga tggcaatgtg tctagtctat ggcatacatc atggggcgga
     4681 ggagatgtag gcaagcctgc aaccatggtc ttgaaagaac caactgaaat cactggactt
     4741 cgttatgttc cacgtggatc aggttcaaat ggtaacttgc gagatgtgaa acttgttgtg
     4801 acagatgagt ctggcaagga gcataccttt actgcaactg attggccaaa taacaacaaa
     4861 ccaaaagata ttgactttgg taagacaatc aaggctaaga aaattgtcct tactggtacc
     4921 aagacatacg gagatggtgg agataaatac caatctgcag cggaacttat ctttactcgt
     4981 ccacaggtag cagaaacacc tcttgacttg tcaggctatg aagcagcttt ggttaaggct
     5041 cagaaattaa cagacaaaga caatcaagag gaagtagcta gcgttcaggc aagcatgaaa
     5101 tatgcgacgg ataaccatct cttgacggaa agaatggtgg aatactttgc agattatctc
     5161 aaccaattaa aagattctgc tacgaaacca gatgctccaa ctgtagagaa acctgagttt
     5221 aaacttagat ctttagcttc cgagcaaggt aagacgccag attataagca agaaatagct
     5281 agaccagaaa cacctgaaca aatcttgcca gcaacaggtg agagtcaatc tgacacagcc
     5341 ctcttcctag caagtgttag cctagcccta tctgctctct ttgtagtaaa aacgaagaaa
     5401 gactagtatt tagtaaaacc tcttaacaag attacggaag cagtctctat cttttccaat
     5461 gaggtttata gtacagaaaa agcctgagaa gatatcttct caggcttttg ttaagcacat
     5521 aaatacaata gtgctatgaa aaaatcaccc agaaaaatct ggatgataaa tgttatggtt
     5581 gtgctggttg aggattctga ttttgttgat caggggttgt atttgattgt tgcgtattat
     5641 tgttaggatt ggtagtcgta ctattatttg tgcttggagt ggttgagcta gactgtgaag
     5701 ttgaactatc tgatgatgag cttgaacttt cagttgatgg gggttgttgt ggagcaggtg
     5761 agctccacgt agaacgagca ccatttttaa atacgaattc tccatttctg tagagcccct
     5821 ctggtatatt ccaatcctct ggattgcttc cttcagacag gtaggtcatc atagagcggt
     5881 aaactttggc agcgaccgta aggccattgc ctacaagtgg tgtcagacgg ttagaatagc
     5941 ctgtccatac agccattgaa tatttacgcg tatagccagc aaatagttca tcaggtgcta
     6001 caaattgaga ggtcttgatg tggttttcaa tttcctcgtc tgtatagtta gaggttcctg
     6061 ttttaccagc ctgagggagc caagcaagat aggcatttcg tccagttcca taactcaaga
     6121 ctgttttcat catttcggtc atcatatagg cagtagtttc tttcatagct cgtgtaccag
     6181 catcagaaaa ttctttttca ctaccatcac taaagacgat tttattgata tacattggtt
     6241 tgtggtaaat accaccatta gcaaaggcgg caaaagcagc agccattttt tcactacttg
     6301 caccgtactg tttgttggat tcagttgtgt tacttgatat ggcgttagaa taatgcatat
     6361 ctggatagtc aattcctaaa ccatttagga agtttttggc tctatctaaa ccaaccttgt
     6421 ttagtgtctc aacggcaggt acgttacgag attgttgaag ggcatattgc agagtaatat
     6481 taccaaaata tgctcgatcc cagttgtaga caggtgtgct tgttcccgga tagttataag
     6541 gaatatcatt aaccatagtt gcagtggaat catatacacc gtattctatg gcaggtgcat
     6601 aatcggtgat tggtttcatt gttgaacccc agtcacgatt ggtttccaca gcttggttgg
     6661 tcccaaatga aacgttactt gcttggtgac gagctccaag ttgggcgatg actttaccat
     6721 ttgaaacatc tacgaccgtg gatgcgactt gcaaatcatc gtcagggtaa gagacgtatt
     6781 gatcggagtt gtagatatcc cacagatgtt tttgagcttc ttggtctaca tttgtgtaaa
     6841 catccatccc agtagttaga aggttatagc cagtttcttg ttctacttgg tcgataacct
     6901 ctttgagata attgtccata tatgctggat agctattgac tgatttcaaa ctttggagtc
     6961 catcagtaat aggggtattg atagccttct catactgttc ggcagaaatg tagccttgac
     7021 ctttcatctc tgaaagtacc aagttacgac ggtcaagggc agcttctgga tgagaatagg
     7081 gatcgtattg attcggagcc tgtggcattc ctgctagtag ggcaagttga ggtagtgata
     7141 gttctctcaa atctttgccg taatagtttt gggcagccgt ctgcattcca tagttcccat
     7201 tagacatgta gaccttattt atatagtagg tcaagatttc ttgcttggtt gctttttgtt
     7261 ctaactgaat cgctaaccaa gcttcctgag ccttacgaga aatagtctgg tcggaagtcg
     7321 aagttgaaaa gtaagtcaac ttaatcaact gttgagtgag agttgatcca ccttggaggg
     7381 aattgctttg cagattgcgc aagaaagctc ccaggatacg gatggtatca atccccctgt
     7441 ggtcgaagaa gcgatggtct tcgatagaaa cgattgcttt aaccaaatct gtgggaatat
     7501 cattagcttg ggcattgacg cggcgttcag aacccaagtc agcaatgagt tgatttttat
     7561 tgtcgtagat tttactagaa gttgttgcaa ctagtttact ctcggatagg ctaggagcct
     7621 tgctaacgta gtagaaaaaa actcctccgc ctaagacaat ggctgcgata accaagctta
     7681 agaagctaat gctcagatac ttgattaggc gcagaatcgt tggtttgttc atcttgtttt
     7741 accacctaat aaatgttctt tgataacatt gagataagga atttgaggga aggcaccagc
     7801 cttgatttca tatccatatt ctcgaatata ttcaagtggc attgattttt gtcccttatc
     7861 ttgatgatag aagcgaatca aatcgaatgc cggcaataag taggtttctt gctgagaaga
     7921 aaagtgaaga aggacaaagc agattccttg ttgggcaagg acttgttcca tatgctgaat
     7981 ctgatgtgga tgaaaatttt tcatcggaat cgcacgtttt tgttttgttt ccttgacttc
     8041 aaagtcgatg taatatccat tataaacgcc agaatagtcc gtcgttgaag cttgtcgaaa
     8101 ataggcttca acaatcttgg cacgacttcg ttgtggatag tccacttgta cgatttgaat
     8161 aggagttggt ttcttatgta tgacagccaa gccctgagac aaatagtagt cgttggtagc
     8221 attgatcatc ttttcaaaag acattcctcg atttgcgaaa tttttgggtt gagaaagaga
     8281 tgtttgtctt ttttgtgatg aaactttatg tggatagttg accataattc tccttattgg
     8341 tacaataaca tcactttatt ataccataat ttgcacagaa agggttaaaa atggctacag
     8401 ctttggtttt aggctattct gcttttgatt tgggtttatt ttctgataag gatcctcgtc
     8461 ttaaattgat taaaaaagcg atacgtaaag atttagaggc tatggcagca gatggggtgt
     8521 cttggcttgt gtttacagga aggttgggtt ttgaatattg ggttttagag gttgctcagg
     8581 agatgaaaac cgaatacggt ttccagttgg ccaccatttt tgcttttgaa acccatgggg
     8641 aaaattggaa tgaaggcaat cagatgaaac tgagtcgctt taagcaggta gactttgtca
     8701 aatatgctta tcctcgctat gaacacaagg ggcagttaag agattaccag cagtttttgc
     8761 tggaaaacac gactagttcc tatctttttt atgatgaaga aaatgaaaca aaactagctt
     8821 atttttacca aaagatgaaa aatcaagagg actattttat aaagagatta acatttgatc
     8881 aattaaatga acttgctgaa aatttttccg aaaattgaag ctttgacctt gatttttgtt
     8941 tgcctttttt tatataataa tactagcaag cgagaatgga gagagacatg gcaagtatta
     9001 ttttttcagc gaaagatatt tttgaacaag agtttggacg tgaagtccgt ggctataata
     9061 aagtagaagt tgacgagttt ttagacgatg tcatcaagga ctatgaaacc tatgctgcct
     9121 tggtcaagtc acttcgtcag gaaattgcgg atttgaagga agaattaact cgtaaaccga
     9181 aaccttcacc agttcaagca gaaccccttg aagcggcaat tacaagttct atgacgaatt
     9241 ttgatatttt gaaacgcctg aatagattgg aaaaagaagt ttttggtaaa caaattttag
     9301 ataactcaga tttttaagta gttatttgag atgtgcaatt tttggataat cgcgtgagga
     9361 gaattgcttc tcatgaggaa agtccatgct agcacaggct gtgatgcctg tagtgtttgt
     9421 gctaggcgaa accataagcc tagggacgag aaatcgttac ggcagttgaa atggctaagt
     9481 ccttggatag gccagagtag gcttgaaagt gccacagtga cggagtcttt ctggaaacag
     9541 agagagtgga acgcggtaaa cccctcaagc tagcaaccca aattttggtc ggggcatgga
     9601 gtatgcggaa acgaacgtag tattctgact gctatcagct agagctgtta gtggtagaca
     9661 gatgattatc gaaggaagtg gtcctagtca cttctggaac aaaacatggc ttatagaaaa
     9721 ttgcatatag gttggggctg agaaattttc tcaacctcat tttttaaagt ggacatatag
     9781 aaaggtcttg caagactgta acatgaaaaa agaatttaat ttaattgcaa ctgtggcagc
     9841 agggcttgag gctgtcgttg gtcgtgaagt gcgagagttg ggctacgatt gtcaggttga
     9901 aaatggacgt gttcattttc aaggagacgt gagagctatt atcgaaacca acctttggct
     9961 tcgggcagca gatcgtatca aaattatcgt aggaacgttc ccagctaaga cttttgaaga
    10021 gctatttcag ggagttttcg ctttagattg ggaaaattat ttaccacttg gagctcggtt
    10081 cccgatttca aaagctaaat gtgttaagtc caaacttcac aatgagccca gtgttcaggc
    10141 tatttctaag aaagctgttg tcaagaaatt gcagaaacac tatgctcgcc cagaaggggt
    10201 tcctctgatg gagaatggcc cagagtttaa gattgaggtc tctattctca aagatgtggc
    10261 aactgtcatg attgatacga ccgggtctag cctctttaaa cgtggttatc gtaccgaaaa
    10321 aggtggcgct cctatcaagg aaaatatggc agcagccatt ttacaacttt ctaactggta
    10381 tccagacaag cctttgattg atccgacctg tggttcgggg actttctgta ttgaggcagt
    10441 tatgattgct agaaagatgg cgccaggtct tcgtcgctct tttgcatttg aggaatggaa
    10501 ctggatcagc gatcgcttga ttcaagaagt gcgcacagaa gcggctaaaa aagtagaccg
    10561 tgagcttgag ctggatatca tgggctgtga tattgatgct cgcatggtgg aaattgctaa
    10621 ggccaatgct caggcagctg gtgttgcagg agacattact tttaagcaga tgcgcgtgca
    10681 ggatttacgt tccgataaaa tcaatggagt aatcatttcc aatccgcctt atggtgaacg
    10741 tttgtcagat gatgcagggg tgaccaagct ctatgctgag atggggcaag tatttgcacc
    10801 gctgaaaact tggagcaaat ttatcctgac tagtgatgaa gcttttgaaa gcaagtatgg
    10861 tagccaagca gataagaagc gtaagttata caacggaacc ttgaaagtgg atctatatca
    10921 atattttggt cagcgtgtca aacggcaaga ggtaaaatag aaagggatac tcatgagtaa
    10981 aaaaagacga aatcgtcata aaaaagaagg tcaagaaccg caatttgatt ttgatgaagc
    11041 aaaagagcta acagttggtc aagctattcg taaaaatgaa gaagtggaag caggagtctt
    11101 gcctgaggat tccattttgg acaagtatgt taagcaacac agagatgaaa ttgaggcgga
    11161 taagtttgcg actcgtcaat acaaaaaaga ggagttcgtt gaaactcaga gtctggatga
    11221 tttaattcaa gagatgcgtg aggctgtaga gaagtcagaa gcttcttcgg aggaagttcc
    11281 atcttctgaa gacatcttac tacccttgcc tctggacgat gaggagcaag gcttggatcc
    11341 tctattgcta gatgatgaaa atccaacaga aatgactgaa gaagtggaag aggagcaaaa
    11401 cctttctcgt ctggatcaag aggactcaga aaagaaaagt aaaaaaggct ttattttgac
    11461 cgttttggcg cttgtatcag taattatttg tgtcagtgct tattatgtct accgtcaagt
    11521 ggctcgttcg accaaggaaa ttgaaacttc tcaatcaact acagccaatc aatcggatgt
    11581 ggatgatttt aatacacttt atgacgcctt ttacacagat agcaataaaa cggctttgaa
    11641 aaatagccag tttgataaac tgagtcaact caaaaccttg cttgataaac tggaaggtag
    11701 tcgtgaacat acgcttgcca aatctaaata tgatagtcta gcaacgcaaa tcaaggctat
    11761 tcaagatgtc aatgcacaat ttgaaaaatc agctattgtg gatggtgtgt tggataccaa
    11821 tgccaaagcc aaatcggatg ctaaatttac ggatattaaa actggaaata cggagcttga
    11881 taaagtgcta gataaggcta ttagccttgg taagagccag caaacaagta cttctagctc
    11941 aagttcaagt caaactagca gctcaagttc aagtccagca agttcaaata cgactagtga
    12001 gccaaaacca agtagttcaa atgagactag aagtagtcgc agtgaagtca atatgggtct
    12061 ctcgagtgca ggggttgctg ttcaaagaag tgccagtcgt gttgcctata atcagtctgc
    12121 tattgatgat agtaataact ctgcctggga ttttgcggat ggtgtcttgg aacaaattct
    12181 agcgacttca cgttcacgtg gctatatcac tggagaccaa tatatccttg aacgtgtcaa
    12241 tatcgttaac ggcaatggtt attacaacct ctataagcca gatggaacct atctctttac
    12301 ccttaactgt aagacaggct actttgtcgg aaatggcgct ggtcatgcgg atgacttgga
    12361 ctactaagca gtcgttacaa aattctttct tttcaaaagt aaaaatgata aaataaaaca
    12421 aatgaaacaa gaggagtgtc aaatgacaaa agctaacttt ggtgtcgtag gtatggccgt
    12481 aatgggtcgt aaccttgccc ttaatattga atcacgtggt tacacagttg ctatctacaa
    12541 ccgtagtaaa gaaaaaacgg aagatgtgat tgcttgccat cctgaaaaga attttgtacc
    12601 aagctatgac gttgaaagtt ttgtaaactc aatcgaaaaa cctcgtcgta tcatgctgat
    12661 ggttcaagct ggacctggta cagatgctac tatccaagcc cttcttccac accttgacaa
    12721 gggtgatatc ttgattgacg gaggaaacac tttctacaaa gataccatcc gtcgtaatga
    12781 agaattggca aactctggta tcaactttat cggtactggg gtttctggtg gtgaaaaagg
    12841 tgcccttgaa ggtccttcta tcatgcctgg tggacaaaaa gaagcctacg aattggttgc
    12901 ggatgttctt gaagaaatct cagctaaagc accagaagat ggcaaaccat gtgtgactta
    12961 catcggtcct gatggagctg gtcactatgt gaaaatggtt cacaatggta tcgagtacgg
    13021 tgatatgcaa ttgatcgcag aaagctatga cttgatgcaa cacttgctag gcctttctgc
    13081 agaggatatg gctgaaatct ttactgagtg gaacaagggt gaattggata gctacttgat
    13141 cgaaatcaca gctgatatct tgagccgtaa agacgatgaa ggccaagatg gaccaatcgt
    13201 agactatatc cttgatgctg caggtaacaa gggaactggt aaatggacga gccaatcatc
    13261 tcttgacctt ggtgtaccat tgtcactgat tactgagtca gtgtttgcac gctacatttc
    13321 aacttacaaa gaagaacgtg tacatgctag caagatgctt ccaaaaccag ctgccttcaa
    13381 ctttgaagga gacaaggctg aattgattga aaagatccgt caagcccttt acttctcaaa
    13441 aatcatttca tacgcacaag gatttgctca attgcgtgta gcctctaaag aaaacaactg
    13501 gaacttgcca tttgcagata tcgcatctat ctggcgtgat ggctgtatca tccgttctcg
    13561 tttcttgcaa aagattacag atgcttacaa ccgtgatgca gaccttgcca accttctttt
    13621 ggacgagtac ttcttggatg ttactgctaa gtatcaacaa gcagtgcgtg atatcgtagc
    13681 tcttgcggtt caagctggtg tgccagtgcc aactttctca gcagctatta cttactttga
    13741 tagctaccgt tcagctgacc ttccggctaa cttgatccaa gcacaacgtg actactttgg
    13801 tgctcacact taccaacgta aagacaaaga aggaaccttc cactactctt ggtatgacga
    13861 aaaataagta ggtcagccat ggggaaacgg attttattac ttgagaaaga acgaaatcta
    13921 gctcattttt taagtttgga actccagaaa gagcagtatc gggttgatct ggtagaggag
    13981 gggcaaaaag ccctctccat ggctcttcag acagactatg atttgatttt attgaacgtt
    14041 aatctgggag atatgatggc tcaggatttt gcagaaaaat tgagccgaac taaacctgcc
    14101 tcagtcatca tgattttaga tcattgggaa gacttgcaag aagagctgga agttgttcag
    14161 cgttttgcag tttcatacat ctataagcca gtccttatcg aaaatctggt agcgcgtatt
    14221 tcggcgatct tccgaggtcg ggacttcatt gatcaacact gtagtctgat gaaagttcca
    14281 aggacctacc gcaatcttag gatagatgtt gaacatcaca cggtttatcg tggtgaagag
    14341 atgattgctc tgacccgccg tgagtatgac cttttggcga cacttatggg aagcaagaaa
    14401 gtattgactc gtgagcaatt gttggaaagt gtctggaagt atgaaagtgc gaccgagaca
    14461 aatatcgtag atgtctatat ccgctatcta cggagcaagc ttgatgttaa aggacaaaaa
    14521 agctacatta aaaccgtgcg tggtgttggt tacaccatgc aagaatagaa aagcagttgc
    14581 agttgtgtaa ctgctttttt gaggagtttt tatatattga catgcagtcg ggtctttgct
    14641 acaatcgttt taggaggata tataaatgaa acttttgaaa aaaatgatgc aagttctact
    14701 agcagtcttt ttctttggtt tgctagctac aaatacggta tttgcgaata ccacaggtgg
    14761 ccgatttgtt gataaggata atagaaaata ttatgtaaaa gatgaccata aagcaatcta
    14821 ttggcataaa atagacggta aaacttacta ttttggtgat attggagaga tggttgtcgg
    14881 ttggcaatac ttagaaattc atggaacagg ttatcgtgat gatttatttg ataatcgtcc
    14941 agtcttcgaa attggccttc aggagaagtg gtactatttt ggacaagatg gtgctttgct
    15001 agaacaaaca gataaacaag tactagaggc aaaaacgtct gaaaatacag gaaaagtata
    15061 cggtgaacaa tatcctctat ctgctgaaaa gagaacttat tattttgata ataattatgc
    15121 tgtaaagaca ggctggattt atgaagacgg caattggtat tatttaaata agctaggaaa
    15181 ttttggcgat gattcttaca atccactacc aattagtgaa gttgctaagg gttggactca
    15241 agattttcat gttactattg acattgatag aagcaaacct gctccatggt actacctaga
    15301 cccagaaact ggcattatgc gaacaggatg gcaatatcta ggtaataact ggtactacct
    15361 ccgttcatca ggagcaatgg ccactggctg gtatcaggaa ggtatcactt ggtattattt
    15421 agaccagcca aatggcgata tgaaaacagg ctggcaatac cttggtaaca agtggtacta
    15481 tctccgttca tcaggagcta tggcaactgg ctggtatcaa gatggttcaa cttggtacta
    15541 cctaaataca agtaatggag atatgacgac aggttggttc caggtcaatg gcaaatggta
    15601 ctatgcttat agctcaggtg ctttggcggt gaatacgacc gtagatggct actacgtcaa
    15661 ctataatggc gaatgggttc ggtaatgaca gggcgcttat aattatatta gaacactcgc
    15721 ttaatcaaag aagtgacttt gttgtacttg acctgacgat tggggagatt aaaagcatgt
    15781 gaaatctaca catgcttttt cgttagttat gagtgttgaa cttgactaac cattgacaaa
    15841 agataagagc aatcaaaata agatacaaaa atatcaatgc taactgcacc gaaacgcccg
    15901 atgctatgga cagggctaat agggagagca gggacggggc gagaatgtct actgtgctca
    15961 gagcagagcc caccgtccca atcttgtcac tggggatatg ggcaaagaca gctgcttgta
    16021 ggcgagggct gagaatgccg ataatcgtag aactgatgaa actggtcatg aaaattacga
    16081 tataggcttg acaaaggata ctagttatta gagtcaatag ggaaatctca cagaaaacca
    16141 agaggtgcgt gaaacggata tttttaaata gattactgct ggtcatattg ccaaggatag
    16201 ctccacaaga aatgatgatg gagagcatgg cgaggagttg cccaatgctc agttgtgcta
    16261 gtgtctgttg gatgaagcgg agggcaatca gccgagggga cacatccaag atggcaatca
    16321 tactggtcgt cagaaacagt agtatgacgg tatcttttaa cctcaggagc acagccagcg
    16381 actgtttaag atgttgaaaa tatttcttaa aactcagtgc tgtatgtgac atttcaatcc
    16441 ttttttcaac ctcatacaag gtatgtctaa taacatacag acccaaaaag gcaatgacaa
    16501 aagtcagagt gttgataagg gaaatagttt gaatactcat aacattgata aggaatgcgc
    16561 cagccagatt ggcgacaatg tggacaaccc tcatcagaga ctgcctgaac cccatggcat
    16621 catgcaggtc gtccttaatt acactgatgt agagggcgtt catcatgtag gcagacaggt
    16681 agctcaaggt gtcagagatg aggttgatga tgacaatcat aatgactgaa actaatgaaa
    16741 agggcgacaa gacgagaaat actgtcaaaa tagcgtagag caggattttg attttggcaa
    16801 tccagagtgc gtgtttgact ctattttctt gaaaatctcc tagaatcccg agaaagagtt
    16861 gcgatagtag gggaaccatc tctgaaatgg aaatcagtaa aatcgctagc ggagcgaaat
    16921 tgtactgagc cacataattg ataatggcga ggtagaaaat actgtcgccg aatgatgaaa
    16981 aacagctgtt tagcagcaac tgtctatata tgttgtttgt ccaaaataat ttcatacttt
    17041 tctccttatg tctgcacatc gaatgggaat ttattattta atagacacca atatacccca
    17101 tgcttcctat tccgaagtca aacaaatctg ttttaccact atctccttga aacatcagta
    17161 aaccgtgatc atctcgttca gaacatgcta aaattacctg ttggattttt tcatcagtaa
    17221 tttgttttga ttgtagacag tggtttgtag taagctagtt attccgtggc aatatcctgt
    17281 catcattttt agatgatggt taaaaacaaa ttcttgatat ttactaataa tatctttgtt
    17341 tccgtcacaa tcgtacatac aaagatataa gattattccg gaaattcctt cgcaccaaga
    17401 aagttgtaaa tttcctaaat tttcagtatt agaagtaact ttttctaata atttttttaa
    17461 ttcagtatgg aatgtatgga gatcattata gaacatagaa ggttctaaga ctttagaata
    17521 ggcaaataaa gcctatgcaa ttccacaata tccatgagca aagctatagt ctaaaatgct
    17581 ttctttggct atatctcttt gtaggaaata atgctaaatt tcccctatac tattgtggat
    17641 gaaagtttta agagtattgt cattggtaaa ttgatagtat tttattaatg ataataggac
    17701 accagatttt cccaatgcaa agtctatttc ctctagagta tcataattct ctattaattt
    17761 cttagcggtg acgtttgcta attgtagata gtattgattt ttactgatag aaaataaatg
    17821 taggagtaac catagatagc ctgcatcacc aaaagatagc ctgcatcacc aaatagcagt
    17881 gagtattgat attcatatgt gtgtgtcgtt ctaattgtca ctgccttctt gatgatagag
    17941 agtattttag aatccagttc tggggggtac aatttattta gaggaaacag tagtccagct
    18001 attccgtgtt ggaatgataa attacttacg aaatttccaa attctgttga agaagtgatc
    18061 cttccttcag aatttacagt tttatctagt aaaaatcgta gaacactatt acattctgtt
    18121 ttgtaatcat atttatgttc ctctattttt ttaattttga ctaaattatt tgtttgactt
    18181 aaatttagta gacattgtaa ccaaaatagt tgctcatctg tgagctgacc ttgagtatgt
    18241 gatagttcta gtaattgaat aggatccttt agttagattc aatcaatcta taacacaaca
    18301 acataataac acttttagga taacttatca aata
//
LOCUS       DAVHSH010000035        18301 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000035 DAVHSH010000000
VERSION     DAVHSH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.035"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            256..537
                     /locus_tag="VVR08_001380"
     CDS             256..537
                     /locus_tag="VVR08_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU6075286.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            669..1613
                     /gene="manA"
                     /locus_tag="VVR08_001381"
     CDS             669..1613
                     /gene="manA"
                     /locus_tag="VVR08_001381"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU6075287.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1634..3112)
                     /locus_tag="VVR08_001382"
     CDS             complement(1634..3112)
                     /locus_tag="VVR08_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEU6075288.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGPLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFRLDIEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKIFFDAMDFLASNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE"
     gene            3217..3966
                     /locus_tag="VVR08_001383"
     CDS             3217..3966
                     /locus_tag="VVR08_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU6075289.1"
                     /translation="MYHIKETAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKDYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3986..4441)
                     /locus_tag="VVR08_001384"
     CDS             complement(3986..4441)
                     /locus_tag="VVR08_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6075290.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4461..5636)
                     /locus_tag="VVR08_001385"
     CDS             complement(4461..5636)
                     /locus_tag="VVR08_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6075291.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5695..6540)
                     /locus_tag="VVR08_001386"
     CDS             complement(5695..6540)
                     /locus_tag="VVR08_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6075292.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6665..7222
                     /locus_tag="VVR08_001387"
     CDS             6665..7222
                     /locus_tag="VVR08_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6075293.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFRETRKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7241..7708
                     /locus_tag="VVR08_001388"
     CDS             7241..7708
                     /locus_tag="VVR08_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU6075294.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7797..8426
                     /gene="upp"
                     /locus_tag="VVR08_001389"
     CDS             7797..8426
                     /gene="upp"
                     /locus_tag="VVR08_001389"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU6075295.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKVLQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8600..9190
                     /gene="clpP"
                     /locus_tag="VVR08_001390"
     CDS             8600..9190
                     /gene="clpP"
                     /locus_tag="VVR08_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU6075296.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9269..9517
                     /locus_tag="VVR08_001391"
     CDS             9269..9517
                     /locus_tag="VVR08_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU6075297.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9618..10778
                     /locus_tag="VVR08_001392"
     CDS             9618..10778
                     /locus_tag="VVR08_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6075298.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLLSPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11046..11915
                     /locus_tag="VVR08_001393"
     CDS             11046..11915
                     /locus_tag="VVR08_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6075299.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11919..12875
                     /locus_tag="VVR08_001394"
     CDS             11919..12875
                     /locus_tag="VVR08_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6075300.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSTSPTYGAFFGAMLVGALLSG
                     VVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12875..13639
                     /locus_tag="VVR08_001395"
     CDS             12875..13639
                     /locus_tag="VVR08_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075301.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13639..14349
                     /locus_tag="VVR08_001396"
     CDS             13639..14349
                     /locus_tag="VVR08_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075302.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNKGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14657..15313
                     /locus_tag="VVR08_001397"
     CDS             14657..15313
                     /locus_tag="VVR08_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6075303.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15421..16516
                     /gene="prfB"
                     /locus_tag="VVR08_001398"
     CDS             join(15421..15492,15494..16516)
                     /gene="prfB"
                     /locus_tag="VVR08_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU6075304.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16534..17226
                     /gene="ftsE"
                     /locus_tag="VVR08_001399"
     CDS             16534..17226
                     /gene="ftsE"
                     /locus_tag="VVR08_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU6075305.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17219..18145
                     /locus_tag="VVR08_001400"
     CDS             17219..18145
                     /locus_tag="VVR08_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075306.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANAPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         5622 a         3445 c         3972 g         5262 t
ORIGIN      
        1 aattgaaact agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg
       61 tcctgatcga tttgccctgt tcttgtttcg ttttactata gaacgatttg aaggcgttta
      121 tgatatttag ctgtacgaga gtctttaaaa agtgttttga tggtttggat ttcttcttta
      181 gttgatttca tatcactatt atataatgct ttttgatttt agtatagtat tatcgtagaa
      241 aatggactcg gtgctatgga tacaccggat gagaatggtt atgtagcaga tgactatcgg
      301 attacttact tagaggccca catcaaggcc atgcgagatg ccatttacaa agacggggtt
      361 gacttgcttg gttatacgac atggggctgt atcgattcgg tttcagctgg cacaggggaa
      421 atgaataagc gctatggctt tatctatgta gatcgagata atgtaggaaa tgggactctc
      481 aaacgtagca agaagaagtc cttctattgg tacatgtcat ttatagcaat ggtgtaagca
      541 tcgagtagag cacatttgtt tactattttt ataaaatctt ctccctgctt tataagatgt
      601 aaaaaagagt tcaattcgaa ctcttttttt gctataatga ggggagaaaa atcagacagg
      661 agatcgacat gtcagaacca ttatttttac aatcagttat gcaagaaaaa atctggggtg
      721 gagccaagct acgtgatgag tttggctacg acatcccaag tgaaaaaatc ggagaatatt
      781 gggccatctc agcccatcca aatggagtct ctaaagttgc caatggtcgt tacgagggaa
      841 cagatcttgc tactttgtat gcggaacacc gtgaattatt tggcaatcgt ccagaacctg
      901 tatttccact tttgaccaag atcctcgatg ccaacgactg gctcagtgtc caagttcacc
      961 cagacgatgc ttatggactc gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca
     1021 ttatcgcagc ggatgaaggt tcagagatta tctacggtca caatgccaag tcaaaagaag
     1081 aactccgcca gcaaatcgag gacaagaact gggatgactt gttgaccaaa gtccctgtta
     1141 aggctggaga tttcttctat gtaccaagcg ggactatgca cgctatcggg gcgggtatct
     1201 taatccttga aacccagcag tctagcgata ccacctatcg cgtctatgac tttgaccgca
     1261 aggatgacaa aggcaacttg cgtgaacttc atcttgaaaa atccatcgat gtcttgaaca
     1321 ttggtgagcc agcaaatagc cgtcctgtaa ctgttaaagc agatgatttg cgttccactc
     1381 tccttgtatc taatgatttc ttcgcagttt acaagtggga aattactgga aaagttgact
     1441 ttgaaaagac agctgactac agcttattga gtgtcttagc tggtcaaggt cagctaactg
     1501 ttgacgggaa aaattatcca attcaaaaag ggagacactt tatcctacca agtgatgttg
     1561 aagcttggac tctggaaggg caaggtttgg aattgattgt tagccatcca taaaaagaaa
     1621 gggcctgagt tcactactca agtccttttt gattacataa attgggcaat gaagaccaca
     1681 atgatgatga ttggaatgac gaaacgaaga aacgaagaag gaagagccag acttggaaca
     1741 gtccttgttt ccatgctctt tcatcgagat ggagttcctc cattgcaaga gcctttttaa
     1801 agatatagcc tgtaaaaagt gaaaggtaga gagctccaaa tggcatgagg agattggaag
     1861 ccaagaagtc catagcgtca aagaagatct taccaaaaat gtgaacatcc gccatgacac
     1921 cgtaagatag ggctgaagga atgccaaaga caaaggtcaa aattcctaaa ataacactcc
     1981 atttggcacg tttgctgtta tcctggttgg tgatattgcc cacattgatc tccagcatca
     2041 cgacagaaga agtgacagtc gcaaagagga aaaggacgta gaaaatggtt ccaaaaggca
     2101 tcttgtcaaa gagttgaggc aagacgataa agagcaagct cggtccccct tcaatatcca
     2161 gtctgaaggg ggaccgagct tggaaaatgg ctagacctgc catgatggat atcgagatat
     2221 tcatggctac gatggagatt cctgactgga ctagattggt tttcttgtcc aagtaagaag
     2281 cataggtcag catgactgta acccctagtg agagggcaaa gaaagattgt cccagagcat
     2341 agaggggacc agcgctagtc agttttgaaa agtctggttt gaggaagtaa agaacccctt
     2401 ccatggcatt tggcaaactg agagagcgac cgatgataac aacaaagatg ataaagagca
     2461 ggggcatcat gactttcgaa gctctttcaa tccctttttg aaccccacgt gatacaataa
     2521 agatatttaa taagataaag gctgcttgag ctactagggc aatggctgga tttgaaatga
     2581 ttgaagtaaa taactgagca taatcacccg ttccaccaag ttggaacaat ttcccaaact
     2641 caatacctag atagactaga atccatcctc cgataacact gtaaaaagat aagaggataa
     2701 agagggcaaa ggcgccaatc caaccgataa agttgtactt gttattcttg cccagttttc
     2761 caaaggtttt gatagcggaa acaccagcac tacggccaag ggcaaactca gccagcagga
     2821 gagggaaacc gattaaaata gtggaaatga gaaagattag taaaaagcct ccaccgccat
     2881 tagcagcagt catgtaggga aacttccaaa cggaaccaag cccgatgacc gagccagcag
     2941 atgctagaat aaaaccaagt ttcgaccccc attgtgattt ttctgacata gttaaactct
     3001 gatctccttt ttcaaaataa gaaaaagcta cttgagttgt caaatagcct tctgtttgat
     3061 tgatagactt gactatccta tcatgttttc taaggtctgt caagaaaatc attttcaagt
     3121 tttcacacct ttctcaaaaa agttaaaaaa ttttctcaaa aacgcttgac tctgacctaa
     3181 ggggaggggt tatactatca ttgtaaggag gaaatcatgt accatataaa agaaactgcg
     3241 cagctttcag gtgtctctgt caagaccctg catcactatg acaagatagg actcttggtc
     3301 cccttaaagt cggaaaacgg ctatcgaacc tacagtcaag aggatttgga acgccttcag
     3361 gtcattcttt actacaaata tctaggcttt tctttagaga aaatagcaga gctgttaaag
     3421 gaagaaagga cagatttatt gccccatttg actaggcagt tggactatct aactcgcgaa
     3481 aggcaacatc tggatacctt gatttccacc ttgcaaaaaa ctattcaaga acaaaaagga
     3541 gaaagaaaaa tgaccattga ggaaaaattc acgggattta gctatcaaga caatcaaaaa
     3601 taccaccaag aagcggtaga gaaatatggt caagaagtca tgggacaagc gctcgaacgc
     3661 caaaaaggtc acgaagacga ggctacggcc gcctttaacc aagtctttca aactttggca
     3721 caaaatcttc aagttggttt acctgcaaca gcaaccgaaa accaagagca agcagccaag
     3781 ctcttgcaag ccattcgcac ttatggattt gactgctcta ttgaggtatt cggtcatatc
     3841 ggtaaagatt acgtctacaa cccagagttt aaggaaaaca ttgacaagtt tggttctgga
     3901 acagcccagt acacgtcaga tgccattgca gcttacgttc agacaaatgc agaaaaaata
     3961 ggctaggaat ttcctagcct attttttact tcaaatcata aagccagtcg tcaccgtttt
     4021 tgtagtaaaa gaattcactg agatcttctt ctagaaacac acgaagcata tcagacatat
     4081 catcggttgc aagttttaga tgagaaagat tttcaaagtc ctcccaccaa actttccctt
     4141 cgtctgaaga ctggagttca ccagtaaagt gttctgtctt gtaaaaaagg acgacataac
     4201 gataatcctt gtcgtcatac cagtttttga taccacagag ttggggtttg gaaatgatca
     4261 gaccagtttc ttctttcact tcacgaatga cagcatcgac aaaggattcg ccacgttcaa
     4321 catgaccacc aggaaaagta atgccaggcc agtcgggact aactcggtct tggaccagga
     4381 ccttatctcc gtttttaatc atacacatgt taacaaattc gactgcctct cttctgttca
     4441 ttcttcacaa cctttaatct ttaatcataa tgcagacttc ccgccaccca gccggtacag
     4501 agggcagaag tgatgttaaa gccacccgtg tgggcattga tatccataac ttcgcctgca
     4561 aagtggaggc caggtaccag cttactttca agggttttag gattgatttc cttgagactg
     4621 actccaccct tggtaacaaa ggactttgca agggacattt ttccagttac aggaatttta
     4681 agttctttaa tggactggac aagctgttct cgttcctttt cagtcagctg tttgactttt
     4741 tcaggatatc cttgtacaaa aaattcggcc aagcgttctg gtaacaaggt ttttaaagcg
     4801 tttttcaagg atttttcccg attttcttct agaaatgtaa ccaagtcctt ctcagaaagt
     4861 tgaggcaaaa catcgagtga gagaacctcc ccacctttga caaagctaga catgcgtagg
     4921 gcagcaggac ctgacaaacc aaagtgggta aagagtaaat catgagtgat gacatgctta
     4981 ccataactta gggtcacatc gtccaaagaa atcccttgta aggctttatg tggaaaatct
     5041 gttaataaag gactttcagc agcctcaaga tcggtgatgg tatgcttaaa atggcgagca
     5101 atctcgtgac caaaaccagt cgaaccagtc gaaggataag acttaccacc tgttgtgaca
     5161 atgagtttct cacaagtgaa ggtttgatcc gctgacttaa ggacaaactg atcatctact
     5221 tttttaacag aaacgatttc tatttgagta gcaacttgac cacctagttc ggtgattttc
     5281 ttttccaaag cttcgataat agtccgagac ttgtcactgg ctggaaagac gcgtccgtgg
     5341 tcttcgacct taagtttaac accattttct gtaaaaaagt tgatgatgtc atgattatcg
     5401 aattgggaga aaacactgta aagaaagcgt ccgtttccag gaattccagc tagcaggttg
     5461 tctaagctac cattgttggt cacattgcaa cgtcccccac cagtcccagc taattttttt
     5521 ccaagtttcc gatttttttc gatgaggagg gttttctgtc cataaaagct actggaaata
     5581 gtagccatca taccagcagg tcccccaccg atgacaatag tatcaaaatg tttcatagct
     5641 ctattgtacc acaaaaaaac aagagatgat ggtcacctct tgtcaagaat gcaattaatc
     5701 aatttcatag cccatcagca aaccgccctc ttctgcatag aaactgcaga gaccagaggt
     5761 tggtagaatt ttaatatccg cttgtgggaa ggtttcacgg attcgctctg agagctgttg
     5821 acaacatttt tcgttattgc gttgggccat gacaatacgg ccaccagcat atccagcttt
     5881 tactaactca tcataggcag cttgaactga tttctttgat ccccttgctt tttgtagcaa
     5941 ttcgagagtc ccagtttcac tagcttttcc gaccatacga atgttgagaa ggccaacgac
     6001 cgtaccgata agcttgctca aacggccgtt cttcaccaag ttatcgactt tggctaggac
     6061 aaagagcaac ttagtttttt cttgataggc ggtgatagct tcaaccactt cttcaaaaga
     6121 caagccctgg tcaatcaagt cattcaattt ttctacgagt aggtcaactt caccaccagc
     6181 agataaacta tcaatcacat gaatcttagt gtcaggatgg tcttccagat aaatattctt
     6241 tgctagttga gcactattgt gactgccaga aagggtacct gtgatggtta ctaggaaaat
     6301 gtttttggca ccttcaaatg ctcgcaaata gtcatctggg cttggacaag ctgattttga
     6361 agcttctgca gttgcataca tggtttccat catttggtca atatcgagac tggcgtcatc
     6421 aacaaagacc tgatcagcta cttgaatggt taaggggaca cttacaaagg ttgtgttaat
     6481 agctggtgtt ggcagttgac gataatcaca accagagtca gcaataatct tccaagtcat
     6541 agaaattctc catctttgtc agttatacat tgacaaaggt tctgtctttt tttacaatta
     6601 tatcatgaaa actcttgaaa caaaagcatc atccgtctgt tgtgacaagt agaaagaaaa
     6661 tgttatgtct gaacgtagaa tctctgaaaa gtctcttgaa aatctcagaa aatcaaacca
     6721 agaatccaat ttattaacca gagaagccat tgaaacagcc ctcttgcaac tcttggaaaa
     6781 aaaggagctg accaagatta gtatttctga attggtcaaa cgtgcaggtg tttcgcgtgc
     6841 ggccttttat cgcaattatg actccaaaga ggaaatttta gagagcgtct ttaaacgaac
     6901 tgtccacaat attatggaac agctgcatca ttacgattta aagacagacc tttatttggt
     6961 ttgggttcac cttttccggg agaccagaaa ggaagctaga gtaattcaat tggccttgga
     7021 ttaccatctg gaaaaaatct ttgtccaagc catgcaggaa tttctagaaa aataccatgg
     7081 gaaatcaaaa ggtgtcagct cttatcttca ttccttctgg agctcagcca tcgtctctgt
     7141 ccttctaaaa tggatcaagg atggcatgaa ggtaccagct gaaaagattg cagatttagg
     7201 tttaccattt tttaaaaaat agagaaaaag gagaaaagag atgactgaaa aaagactggc
     7261 ctgggatgag tattttgcag cccaagccct actaattgcg aatcgttcca cttgtaaacg
     7321 tgctaaagtg ggcgcgattc tggtaaaaga taataaggtt atttccactg gttacaatgg
     7381 ttcggtgtca gggactgagc attgtattga tcacgaatgt ttggtcattg aaggccactg
     7441 tgttcgcacc cttcacgctg aggtcaatgc tatccttcaa ggtgctgagc gtggtgttcc
     7501 caaaggcttt acagcctatg taacccattt tccttgtctc aactgtacaa aacaattgct
     7561 tcaggtcggc tgcaagcgcg tggtttatat caaccagtac cgaatggacg actacgccca
     7621 atacctttat caagaaaaag ggacagaatt gacccattta ccacttgaga cagtacagac
     7681 agctcttaaa gaggctgatc taatgtaaaa attatcaaaa ataaatggtt tagaaagatt
     7741 tttaaaccgt tttttggtat aataagaaga ataaattgaa agaaggaatt ccaaaaatgg
     7801 gaaaaattga agttattaat cacccactga ttcaacacaa attgtcaatc ttgcgtcgta
     7861 cagatacttc tacaaaagct tttcgtgagc tagtagatga gattgcaatg ttgatggggt
     7921 atgaagtact tcgtgatctt ccactagaag atgtggaaat cgaaacacca attacaaaaa
     7981 cagttcaaaa acaattggca ggtaagaaat tggccatcgt cccaatcttg cgtgcaggta
     8041 tcgggatggt tgatggtctc ttgagcttgg ttccagctgc taaagttggc cacatcggta
     8101 tgtaccgtga tgaagaaaca cttcaaccag ttgaatactt ggtgaaattg cctgaggaca
     8161 ttgaccaacg tcaaattttt gtagtagatc caatgttggc aacaggtggc tcagcaatct
     8221 tggctgttga ttctcttaaa aaacgtggcg catcaaatat caaatttgtc tgccttgtat
     8281 ctgctccaga gggtgtaaaa gtccttcaag aagctcatcc agatgtagaa atctttacag
     8341 cagccttgga tgaacgtttg aacgaacacg gttatatcgt tccaggtctt ggagatgctg
     8401 gagaccgctt gttcggtaca aaataagatc gaaaagaaga atgacttgga aaagtatttc
     8461 cagtcacgaa aggaggttgg gtttttgttt ctgtctaatg aaagcagagc aaaaatttga
     8521 ccttttttga ccaagatatt ataatagtct tatcttcagt catttgacca acaaaattaa
     8581 aactcaaaag gagaaatgaa tgattcctgt agttattgaa caaacaagcc gtggagaacg
     8641 ttcttacgat atttactcac gtcttctcaa agaccgcatc attatgctga caggtccggt
     8701 tgaagacaat atggctaact ctgttattgc ccaattgctt ttcttggatg cccaagatag
     8761 tacaaaagat atttaccttt atgtcaatac accaggtggt tctgtttcag ctggtttggc
     8821 aatcgtagat accatgaact ttatcaaggc agatgtccaa accattgtta tgggaatggc
     8881 tgcatctatg ggaacagtca tcgcatcaag tggagcaaaa ggcaaacgtt tcatgcttcc
     8941 aaatgctgaa tacatgattc atcaaccaat gggcggtaca ggtggtggta cccaacaaac
     9001 tgatatggct atcgctgcag aacacttgct caaaactcgt aataccttgg aaaaaatctt
     9061 ggctgaaaat tcaggtcagt caatggaaaa agtccatgca gatgcagaac gtgataactg
     9121 gatgagcgcc caggaaacac ttgaatatgg ctttattgat gaaattatgg ccaacaattc
     9181 attgaactaa tgatgataga aggcaaactc gactgggttt gctttttttg gtataatagg
     9241 gagagatttc ttagaaagag gatttatcat gtttgaaaaa gtcaatcgct ctggcttgat
     9301 tatctatctt tactataatc gtgatgccaa aaaactgcag gattatggag atattaccta
     9361 tcattccaag aaacatcgtt acttacaact ctatgttcca actcaagaag tggagcaatt
     9421 ggtcggacgc ttgagcaagg aaaaatttat taaaaaagtt agggtttgtc atatccaaga
     9481 gttggaaaca ccctttgtgg gcaatcttta tcgataggaa aacgttatca tcgaaaaagt
     9541 tcaaggaaaa cattgacaat tttctgataa ttcggtatat tcttaacaga ctatttaaga
     9601 aataaggaga caaaaagatg aagaaaaaat ttgccctatc gtttgtggcg cttgcaagtg
     9661 tagcacttct tgcagcctgt ggagaagtga agtctggagc agtcaacact gctggtaact
     9721 cagtagagga aaagacaatt aaaatcgggt ttaactttga agaatcaggt tctttagctg
     9781 catacggaac agctgaacaa aaaggtgccc aattggctgt tgatgaaatc aatgccgcag
     9841 gtggtatcga tggaaaacaa atcgaagtag tcgataaaga taataagtct gaaacagctg
     9901 aggctgcttc agttacaact aaccttgtaa cccaatctaa agtatcagca gtcgtaggac
     9961 ctgcgacatc tggtgcgact gcagctgcgg tagcgaacgc tacaaaagca ggtgttccat
    10021 tgctctcacc aagtgcgact caagatggat tgactaaagg tcaagattac ctctttattg
    10081 gaactttcca agatagcttc caaggaaaaa ttatctcaaa ctatgtttct gaaaaattaa
    10141 atgctaagaa agttgttctt tacactgaca atgccagtga ctatgctaaa gggattgcca
    10201 aatctttccg cgagtcatac aagggtgaaa tcgttgcaga tgaaactttc gtagcaggtg
    10261 acacagactt tcaagcagcc cttacaaaaa tgaaagggaa agactttgat gctatcgttg
    10321 ttcctggtta ctataatgag gctggtaaga ttgtaaacca agcgcgtggc atgggaattg
    10381 acaaaccaat cgttggtggt gatggattca acggtgagga gtttgtacaa caagcaactg
    10441 ctgaaaaagc atcaaacatc tactttatct caggcttctc aactactgta gaagtttcag
    10501 ctaaagctaa agccttcctt gacgcttacc gtgctaagta caatgaagag ccttcaacat
    10561 ttgcagcctt ggcttatgat tcagttcacc ttgtagcaaa cgcagcaaaa ggtgctaaaa
    10621 attcaggtga aatcaaggat aaccttgcta aaacaaaaga ttttgaaggt gtaactggtc
    10681 aaacaagctt cgatgcagac cacaacacag tcaaaactgc ttacatgatg accatgaaca
    10741 atggtaaagt tgaagcagca gaagttgtaa aaccataata gaaaaatgtt gaaataggga
    10801 atgagccttt gactcactcc ctgtttcgat atttaatact cttcgaaaat ctcttcaaac
    10861 tgcgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta tctacaacct
    10921 caaagcagtg ctttgagcaa cctgtggcta gtttcctagt ttgctctttg attttcattg
    10981 agtataagaa cctatcaaaa agtgagggaa acccctcgga attataaata gaaagagtga
    11041 atcttatgct ccaacaactc gtaaatggtt tgattctagg tagtgtttac gcgctgttag
    11101 ccctaggata taccatggtt tacggaatta tcaagctcat caacttcgcc catggtgata
    11161 tttatatgat gggagccttt atcggttatt tcttgatcaa ttctttccaa atgaatttct
    11221 ttgtagcgct tattgtagct atgctagcga cagctattct tggtgtcgtg attgagtttc
    11281 ttgcttaccg acctttgcgc cactctactc gtattgctgt tttgattacg gctattgggg
    11341 tttctttcct attggagtat ggaatggtct atctggttgg tgccaatacc cgtgccttcc
    11401 ctcaagcgat tcaaacagtt cgatatgatt tgggaccaat tagcttaaca aatgtgcagt
    11461 taatgatttt ggctatttcc ttgattttga tgattttgtt acaagtcatt gtccaaaaga
    11521 ctaagatggg gaaagccatg cgtgcagtat cagtagatag cgacgcggcg caattgatgg
    11581 ggatcaatgt aaaccgtacg attagcttta ccttcgcttt gggttctgct cttgcgggtg
    11641 cggctggtgt tctgattgct ctttattata actctcttga gcctttgatg ggggttactc
    11701 caggtcttaa atctttcgtt gccgcagtac ttggtggtat cggaattatt cctggtgcgg
    11761 ctcttggtgg ctttgtgatt ggtctattgg aaacctttgc gactgccttt gggatgtcag
    11821 atttccgtga tgccattgtt tatggaatct tgttgttgat cttgattgtc cgcccagctg
    11881 gtatccttgg taagaatgtg aaagagaagg tgtaaacgat gaaggaaaat ttaaaagtta
    11941 atattctatg gttactcctt ttgttagctg gctatagctt gattagtgta ctggtttcag
    12001 tcggagtact taatctattc tatgtacaga ttttacaaca aattggaatt aatattattt
    12061 tggctgttgg tctcaactta atcgttggtt tttcaggaca attttcactt ggtcatgctg
    12121 gtttcatggc gattggtgcc tatgcagcag ctattattgg ttctacatca ccaacctacg
    12181 gtgccttctt tggagctatg cttgtagggg ctttgctttc aggagtagtt gccttacttg
    12241 tcggcattcc aaccttgcgc ttgaaggggg actatcttgc ggtagcaact ctgggtgttt
    12301 ctgaaattat ccgtatcttt atcatcaatg gtggaagtct tacaaatggt gcggcaggta
    12361 tcttagggat tcctaacttt acaacttggc aaatggttta cttctttgtc gtgattacaa
    12421 ccattgcaac cttgaacttc ttgcgtagcc caattggccg ttcaaccctc tctgttcgtg
    12481 aagatgaaat cgctgctgag tcagttgggg ttaatacgac taaaattaaa atcatcgctt
    12541 ttgtctttgg tgccattact gcaagtattg ctgggtcact tcaggcagga tttatcgggt
    12601 ctgttgtacc gaaagattac accttcatca actcaatcaa cgttttgatt attgttgtat
    12661 ttggtggact cggttccatt acaggtgcga ttgtttcggc tattgttctg ggaattttga
    12721 atatgcttct ccaagatgtt gctagtgtgc gtatgattat ttacgctttg gccttggtat
    12781 tggtaatgat tttcagacca ggtggactcc ttggaacatg ggaactgagc ctatcacgtt
    12841 tctttaaaaa atctaagaag gaggaacaaa actaatggca ttacttgaag taaaacagtt
    12901 aaccaaacat tttggtggtc taacagctgt tggagatgtg actcttgaat tgaacgaagg
    12961 ggaactggtt ggattaatcg gtccaaacgg agctgggaaa accacccttt tcaacctttt
    13021 gaccggtgtt tatgaaccaa gcgagggaac agtaacccta gatggtcacc ttttgaatgg
    13081 gaaatcacct tataagattg cctctttggg acttggacgt actttccaaa atatccgtct
    13141 ctttaaagat ttaacagttt tagacaatgt tttgattgct tttggaaacc atcacaaaca
    13201 gcatgttttt actagtttct tacgcttacc agctttttac aagagtgaaa aagaattaaa
    13261 ggctaaagct ttggaattgt tgaaaatctt tgatttagat ggtgatgcag agactcttgc
    13321 taaaaatctt tcctacggac aacaacgtcg tttggaaatt gttcgtgccc ttgctacgga
    13381 acctaaaatt ctcttcttag atgaaccagc agcaggtatg aacccacagg aaacagccga
    13441 attgactgag ttaattcgtc gtatcaaaga tgaatttaag attacaatca tgttgattga
    13501 acacgatatg aatctggtca tggaagtaac agaacgtatc tacgtacttg aatatggccg
    13561 tttaattgct caaggaactc cagacgaaat taagaccaat aaacgcgtta tcgaagctta
    13621 tctaggaggt gaagcctaat gtctatgtta aaagttgaaa atctttctgt gcattacggt
    13681 atgatccaag cagtccgtga tgtaagcttt gaagttaata aaggagaagt tgtttccctt
    13741 atcggtgcca atggtgcagg taagacaact attcttcgca ccttgtcagg tttggttcga
    13801 ccaagttcag gaaagattga atttttaggt caagaaatcc aaaaaatgcc agctcagaaa
    13861 atcgtggcag gtggtctttc acaagttcca gaaggacgcc acgtctttcc tggcttgact
    13921 gttatggaaa atcttgaaat gggagctttc ttaaagaaaa atcgtgaaga aaatcaagct
    13981 aacttgaaga aggttttctc acgctttcct cgtcttgaag aacggaagaa ccaagatgca
    14041 gctactcttt caggagggga acaacaaatg cttgccatgg gacgcgctct tatgtcaaca
    14101 ccaaaacttc ttcttttaga tgaaccatca atgggacttg ccccaatctt catccaagag
    14161 atttttgata tcattcaaga tattcagaag cagggaacaa ccgtcctctt gattgaacaa
    14221 aatgccaata aagcacttgc aatctctgac cgaggatatg tattggaaac aggaaaaatc
    14281 gtcctatcag ggacaggaaa agaactcgct tcatcagaag aagtcagaaa agcatatcta
    14341 ggtggctaaa acaatccaga ggattgtttt agccggcaga tggagattac gaagtaatca
    14401 tcaatatagt ccgggggacc tttttagtcg gtagattgag attgcaaaca aatatgcatc
    14461 tacattgaaa gcttaatttc taataattga aaaaatcgaa tgaaaaattt cttaccttca
    14521 ttcacagagc tctatttcag agctcttttt gctagcttat tcatactttt ctgaatttcg
    14581 aaaaagaaat gtaagcgttt gatagatttg caaaaagatt gtataatagg gataagaata
    14641 gaaaaggaga agtctcatgg cagttaaaga ttttatgacc cgcaaggtag tttatattag
    14701 tccagataca acagtatctc atgcagcaga tttgatgaga gagcaaggtt tgcaccgtct
    14761 gcctgttatc gaaaatgatc aattagttgg tttggtgact gagggaacca ttgcacaagc
    14821 aagtccatct aaagcaacaa gtctttctat ctatgagatg aattatcttc tgaataagac
    14881 aaaagtaaaa gatgtcatga ttcgcgatgt tgtcactgtc tcaggctatg ctagtctaga
    14941 agatgcaact tatctgatgt tgaaaaataa gattagtatt ctccctgtcg tagataacca
    15001 tcaagtatac ggagttatta ctgaccgtga cgttttccaa gcctttcttg aaattgcagg
    15061 ttatggcgaa gaagggattc gtgtacgctt tgttacagaa gatgaagttg gtgttcttgg
    15121 aaaaattgtt tctttgattg tagaagaaaa tttgaatatc tcccatacag tcaatattcc
    15181 gcgtaaggat ggtaaggtga ttatcgaagt gcaaatcgat ggatcaattg atttaccagc
    15241 cttgaaagaa aaatttgaag caaatggtat tcaagtggaa gaaatcgctc gcacttcagc
    15301 aaaagtcttg taagaaggga agcccaaagg cttctttttt catgaaaagg ggattagaga
    15361 aaaagatgga aagaaatgat aaaatatgct ataatgaaat aatgtaaaaa aggagtattt
    15421 atggacattt cagtaattcg tcagaaaatt gacgcaaatc gtgaaaaatt agcttctttc
    15481 agggggtctc tttgacctcg aagggctaga ggaagagatt gccatcttgg aaaacaagat
    15541 gacagaacct gatttttgga acgataatat tgcggcccaa aaaacgtcgc aagaattaaa
    15601 tgaattaaaa aacacttaca ataccttcca taagatggaa gagttgcagg atgaagtcga
    15661 aattttattg gattttttgg ctgaagacga gtcagtgcat gatgaactgg tagcgcagtt
    15721 agccgaactt gataagataa tgaccagcta cgagatgact ctactcttgt cagaacctta
    15781 tgaccacaac aatgccatct tggaaatcca tccaggttct ggtggtactg aggcgcagga
    15841 ctggggtgat atgttgcttc gtatgtatac tcgttatggt aatgctaaag gctttaaagt
    15901 ggaagtgttg gattaccaag caggtgatga ggctggtatt aagtcggtaa ctttatcatt
    15961 tgaagggcct aatgcctatg gtctcctcaa gtcagaaatg ggtgttcatc gcttagtgcg
    16021 aatctcacca tttgactctg ccaaacgtcg ccatacctct ttcacatctg tagaagtgat
    16081 gccagaattg gatgatacta ttgaagtgga aatccgtgaa gatgatatca agatggatac
    16141 cttccgttca ggtggtgccg gtggacaaaa cgtcaataaa gtttcaacag gtgtacgttt
    16201 aacccacatt ccaactggaa ttgttgtcca atcaacagtg gatcgtaccc agtatggaaa
    16261 tagagatcgt gccatgaaga tgttgcaggc taagctctat caaatggagc aagataagaa
    16321 ggctgcggag gtagattctc tcaaaggtga gaaaaaggag atcacttggg gaagccaaat
    16381 ccgttcttat gtcttcacgc cttatactat ggtaaaagat caccgaacta gctttgaggt
    16441 tgctcaggta gataaggtta tggatgggga cctagatggt tttatcgatg cttatctcaa
    16501 gtggcgaatt agctaagata gaaaggaact cacatgtcaa ttattgaaat gagagatgtc
    16561 gttaaaaaat acgacaacgg aacgactgct ctacgcggtg tttcggtcag cgttcaaccg
    16621 ggggaatttg cttacatcgt aggaccttca ggagcaggga agtcaacttt tattcgttct
    16681 ctgtatcgtg aagtaaaaat cgataaagga agcctatcag ttgctggttt taatctggtt
    16741 aagatcaaaa agaaagatgt cccgcttcta cgtcgtagtg ttggggttgt cttccaggat
    16801 tataaattgt taccaaagaa aactgtctat gaaaatattg cttacgctat ggaagtaatc
    16861 ggggaaaatc gccgtaatat caaaaaacga gtgatggaag ttttggactt ggttggattg
    16921 aagcataagg ttcgttcttt cccaaatgaa ctctcaggtg gggagcaaca gcggattgcg
    16981 attgcgcgtg caattgtaaa taatcccaaa gtattgatag ctgatgagcc aacaggaaat
    17041 ctggatccgg ataattcatg ggaaattatg aatctcttgg aacggattaa cctacaaggg
    17101 acaactattt tgatggcgac tcataatagc cagattgtaa ataccttgcg ccaccgtgtc
    17161 attgccattg aaaatggccg tgtcgttcgt gacgaatcaa aaggagagta tggatacgat
    17221 gattagtaga ttttttcgcc atttatttga agccttaaaa agtttgaaac gaaatggttg
    17281 gatgacagta gctgctgtca gttcagtcat gattactttg accttggtgg caatatttgc
    17341 atctgttatt ttcaatacag cgaaactagc tacagatatt gaaaataatg tccgtgtagt
    17401 agtttatatc cgaaaggatg tggaagataa tagtcagaca attgaaaaag aaggtcaaac
    17461 tgttacaaat aatgactacc acaaggtata tgattctttg aagaacatgt ctacggttaa
    17521 aagtgttacc ttttcaagta aagaagaaca atatgaaaaa ttaaccgaga taatgggaga
    17581 taactggaaa atctttgaag gagatgccaa tcctctctat gatgcctata ttgtagaggc
    17641 aaacgctcca aatgatgtaa aaactatagc cgaagatgct aaaaaaattg aaggtgtctc
    17701 tgaggttcaa gatggcggtg ccaatacaga aagactcttc aagttagctt catttatccg
    17761 tgtttgggga ctagggattg ctgctttgtt aatttttatc gcagttttct tgatttcaaa
    17821 taccattcgt attaccatta tttcccgcag tcgcgaaatt caaatcatgc gcttggtcgg
    17881 agctaaaaac agttatatcc gtggaccgtt cttgttagaa ggagccttta tcggtttatt
    17941 gggagctatc gcaccatctg ttttggtctt tattgtttat caaattgttt accaatctgt
    18001 caacaaatcg ttggtagggc aaaatctatc catgattagt ccagatttat ttagtccgtt
    18061 gatgattgcc ctactatttg tgattggggt tttcattggt tcattgggat caggaatatc
    18121 catgcgccga ttcttgaaga tttaggtaaa atagctgctt ttatgaggag attgtaaaat
    18181 ctcctttttt gctacaagag tttttgaaaa gagatgcgta gaagaaaaga gcttccaaag
    18241 aagtccccca gagaagactt cttgatggct aatttgaact tgaaatttgg cgcactagaa
    18301 a
//
LOCUS       DAVHSH010000036        18282 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000036 DAVHSH010000000
VERSION     DAVHSH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.036"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..342
                     /locus_tag="VVR08_001401"
     CDS             <1..342
                     /locus_tag="VVR08_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU6075307.1"
                     /translation="KPNEEKPQTEKPEEETPREEKPQSEKPESPKPTDEPEEESPEES
                     EEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEA
                     EKLLALLKESK"
     gene            764..994
                     /locus_tag="VVR08_001402"
     CDS             764..994
                     /locus_tag="VVR08_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEU6075308.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1391..2104
                     /locus_tag="VVR08_001403"
     CDS             1391..2104
                     /locus_tag="VVR08_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU6075309.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2162..2764
                     /locus_tag="VVR08_001404"
     CDS             2162..2764
                     /locus_tag="VVR08_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075310.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKERDYIGRRDSQVDNLRVIGNIFLNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2900..3553
                     /locus_tag="VVR08_001405"
     CDS             2900..3553
                     /locus_tag="VVR08_001405"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU6075311.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            3563..4027
                     /locus_tag="VVR08_001406"
     CDS             3563..4027
                     /locus_tag="VVR08_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6075312.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDIHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4040..5308
                     /locus_tag="VVR08_001407"
     CDS             4040..5308
                     /locus_tag="VVR08_001407"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU6075313.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     NATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLIEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5322..5582
                     /locus_tag="VVR08_001408"
     CDS             5322..5582
                     /locus_tag="VVR08_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075314.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5593..6954
                     /gene="pdrM"
                     /locus_tag="VVR08_001409"
     CDS             5593..6954
                     /gene="pdrM"
                     /locus_tag="VVR08_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU6075315.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7108..8076
                     /locus_tag="VVR08_001410"
     CDS             7108..8076
                     /locus_tag="VVR08_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU6075316.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8092..9084
                     /locus_tag="VVR08_001411"
     CDS             8092..9084
                     /locus_tag="VVR08_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU6075317.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9302..10345
                     /locus_tag="VVR08_001412"
     CDS             9302..10345
                     /locus_tag="VVR08_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU6075318.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10409..12094
                     /gene="lpdA"
                     /locus_tag="VVR08_001413"
     CDS             10409..12094
                     /gene="lpdA"
                     /locus_tag="VVR08_001413"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU6075319.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12158..13147
                     /locus_tag="VVR08_001414"
     CDS             12158..13147
                     /locus_tag="VVR08_001414"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU6075320.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13214..14284)
                     /gene="xerS"
                     /locus_tag="VVR08_001415"
     CDS             complement(13214..14284)
                     /gene="xerS"
                     /locus_tag="VVR08_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU6075321.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14868..16418)
                     /locus_tag="VVR08_001416"
     CDS             complement(14868..16418)
                     /locus_tag="VVR08_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU6075322.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLRLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16434..17213)
                     /locus_tag="VVR08_001417"
     CDS             complement(16434..17213)
                     /locus_tag="VVR08_001417"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU6075323.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17200..18051)
                     /gene="ylqF"
                     /locus_tag="VVR08_001418"
     CDS             complement(17200..18051)
                     /gene="ylqF"
                     /locus_tag="VVR08_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU6075324.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
BASE COUNT         5557 a         3392 c         3882 g         5451 t
ORIGIN      
        1 aaaccaaacg aggagaaacc tcagacagaa aaacctgagg aagaaacccc tcgagaagag
       61 aaaccgcaaa gcgagaaacc agagtctcca aaaccaacag acgaaccaga agaagaatca
      121 ccagaggaat cagaagaacc tcaggtcgag actgaaaagg ttgaagaaaa actgagagag
      181 gctgaagatt tacttggaaa aatccaggat ccaattatca agtccaatgc caaagagact
      241 ctcacaggat taaaaaataa tttactattt ggcacccagg acaacaatac tattatggca
      301 gaagctgaaa aactattggc tttattaaag gagagtaagt aaaggtagca gcattttcta
      361 actcctaaaa acaggatagg agaacgggaa aacgaaaaat gagagcagaa tgtgagttct
      421 agttctcatt tttttcatga aaatgtgcaa aatatagtag attgaaacta gaatagtata
      481 cctctacttc taaaacattg ttagaaatcg atttgactgt cctgttctta tttcatttta
      541 ctatatctta acagatagtg taaataaaga taaactattt actggctaat taatcagtta
      601 aacactagtt aaggagtaat gatgaaaaaa agaacaatac tattattaat ggccagtctg
      661 ttagctcttg tcttaggagc atgtggtttc ttggacatat tgatcctgga tcattctcat
      721 caggattact ctttactgct attttagaaa ctggggtggt ttgatggaaa gtattggtat
      781 tggtcttgtt atcgtttcac attccaaaca cattgcagaa ggtgttgttg aactgattag
      841 taaagtagct aaagatgttc cgattactta tgtaggagga accgagggcg gaggaattgg
      901 aacgagtttt gatcaagtag atagggttgt ttccgaaaat ccagcagata ctttacttgc
      961 cttttttgac ctaggttctg ctataaaatg ttaagtaaat gatttcaaaa tcagaaaggg
     1021 attgctttat gcagttcctt tttattttaa caggagtgaa actatagtgt ttctaaattg
     1081 tgaatcaatc aaaactgatt gtgatggggc tattctagct ttagaaacct tcaaaaatta
     1141 aaatttaagg caatcaatta cttggaagag tatgaaagca tttagtttat aggaattcta
     1201 ggcctagaat tacatatgta tttatgaaga cggggtgttc gatagttagt attgttctat
     1261 tctgaaagat ttgagctgtc agttgtatag aaagtgttcg aatttttttt aagtgattaa
     1321 attagttaat tgtatgaggt gctttatgat ataatgttct taatgaattt tcagaaagga
     1381 aaacctcaaa ttgttctaca aatttctact cttcgacctc gaccacactc ttcttgattt
     1441 tgatgctgct gaggatgtgg ctttgaccca acttctaaaa gaagaaggag ttgcggatat
     1501 tcaggcttat aaagattatt acgttcctat gaacaaggct ctctggaaag acttggagct
     1561 gaagaaaatc agtaaacaag agctggttaa cacgcgattt tctcgtttat ttgctcattt
     1621 tggacaggaa aaagacggta gttttcttgc ccagcgttac caattttacc tcgcccagca
     1681 gggacaaaca ctatcgggcg ctcatgatct cttggacagc ctcattgagc gtgattataa
     1741 cttgtatgct gcgacaaatg gcattactgc cattcagaca ggacgtttgg ctcaatctgg
     1801 tctagcacct tatttcaatc aagtctttat ctcagaacag ttgcaaactc aaaagccgga
     1861 tgctctcttt tatgaaaaga ttggccagca aattgctgga tttagtaaag aaaagacgct
     1921 gatgattgga gattctctaa ctgccgacat tcaaggtggc aataatgcgg ggattgacac
     1981 tatctggtat aatcctcatc acctcgaaaa tcacacacaa gcccagccga cttacgaagt
     2041 ctattcttac caagacttgc tggattgttt agataaaaat attcttgaaa agatcacatt
     2101 ttaaaggaga cgagctaatg actacaaaaa agctaatatt actattgaag agtacattga
     2161 aatgtctgaa gttgatttta atgaagctgt taattatgaa tttacatctg acacttgtca
     2221 attagcaaat agtatttatc aatctctttt taagtttttt gataagaaaa atttctctgg
     2281 cgatttaatt tttacttgga aatctccatc attagtcaaa gaaagggatt atattgggag
     2341 aagggattca caagtagata atcttagagt aataggaaat atatttctga attatcttac
     2401 taatcgaaaa tatagcctca atatgaatcg taatggctgt atgggagatt ttcctcatga
     2461 cttttttgat atatacctag atcatgtagc aaaatatgcc tacgaacaaa aagttaataa
     2521 tattaaagag tattatcctt taaaaagagc gattttacac caagagaatg cattgtattt
     2581 tcgatttttt tctaattttg acgacttttt agaaaaaaat tatttaaaga ctatatggca
     2641 agtttctaaa gaaactcctt tttctgaaat ggattttaat atgtttaaaa atatttcaga
     2701 aaagataatc ttcgaaagag gtagtaaaat gcttaatgat ttaaaaagta attataaaaa
     2761 atagccagtc tttataaact gtattcacgt attcaaatcg tatatagtcg atttattaaa
     2821 tctttagata aactgtaaaa agtggtttcc atagccactt tttgctataa tagaggcagt
     2881 aaaaatgaag gagtcggcta tggaacactc gtcttggcat gctttgatta aggcgcaatt
     2941 acctgagggt tatttcggga aaatcaatca gtttatggag caggtctatt ctcaggggat
     3001 tatttatcca cccaaggaaa aggtttttca ggctctcttg acaacactgc ttgaagaagt
     3061 taaggtggta attctagggc aagaccccta tcacggacca ggtcaagcgc agggcttgag
     3121 tttttccgta cctgactcta tcccagctcc accatccttg caaaatatct tgaaagaatt
     3181 gtcagatgat atcggagtta agaaatctca tgatttgaca gcttgggctg agcaaggagt
     3241 cttgcttctt aatgcttgtt tgactgttcc tgctggacag gccaatggtc atgctggtca
     3301 aatctgggag ccttttactg atgctgtgat tcaggtggtc aatcatctag atagaccagt
     3361 cgtttttgta ctctggggag cttatgcacg taagaagaag gccttagtta ccaatcctca
     3421 tcacttgatt attgaatcag cccatccaag tcctttgtcg gtttatagag gattttgggg
     3481 ttccaagcct ttttccaagg ccaatacatt cttaaaagag acaggacaag agccaatcga
     3541 ttggcttaga taaggagaaa atatgcctca gttagcgacg atttgttaca ttgataatgg
     3601 gaaagaactg ctcatgctcc atcgtaataa gaaacccaat gatatccatg aagggaaatg
     3661 gattggtgtg ggtggtaagc tagagagagg agagacgccc caggaatgcg cggtacgtga
     3721 aatccttgaa gaaacagggc tcaaagccaa gccagttcta aaaggtgtca tcacttttcc
     3781 tgaatttaca ccagatttag actggtacac ctatgttttt aaggtgacgg agtttgaggg
     3841 cgacttgatt gactgcaatg aggggacgct agaatgggtt ccctatgacg aggttttgag
     3901 caagccgact tgggaaggtg accacacctt tgttgagtgg cttttagagg ataaaccctt
     3961 cttttcagcc aagtttgttt atgatgggga taaattgttg gatacccaag ttgatttcta
     4021 tgaataaagg agaaagcaga tgctactaat caaaaatggt cgtgtaatgg atcctaagtc
     4081 tggtttggat caagtttgtg atgtcttagt tcaagatggg aaaattatca aaattgcgcc
     4141 tgagatcacg gaagaaggag cagaaacgat taatgctact ggtcttgtgg ttgctcctgg
     4201 tttggtcgat attcatgtgc atttccgtga acctggtcaa acacataaag aagacattca
     4261 tactggtgcc ctagcagccg ctgcaggtgg ttttactact gtcgtcatga tggctaatac
     4321 cagtccaacc atttcagacg tggagacttt gcaagcagtt ctccagtcag ctgccaaaga
     4381 gaagattaat gtcaagacag ttgcgaccat tactaaaaac tttaatggta aaaacttgac
     4441 tgactttaag gcactcttag aagctggtgc ggttggtttc tctgatgacg gtattccgct
     4501 tgagagcagt aagattgtca aggaagccat ggaggaagcc aaaaaactca atacctttat
     4561 cagccttcat gaggaagatc caggtttgaa cggtgttctt ggctttaatg aaaatattgc
     4621 tagagaacat ttccatatct gcggtgctac tggggtggct gagtacgcta tgatggcgcg
     4681 tgatgtcatg attgcctatg caactaaagc ccatgttcac atccagcatt tgtctaagga
     4741 agaaagtgtt aaagtagtgg agtttgctca ggggttaggt gcagaagtca cagcagaagt
     4801 agcgccacag catttctcta agacagaagc acttctttta acacaaggta gcaatgctaa
     4861 gatgaatcca ccgcttcgtt tggaatcaga ccgtcgtgcc gttatcgaag gtctcaaatc
     4921 aggtgtcatc acagttattg cgactgacca cgcgcctcat catgtagatg aaaaaaatgt
     4981 tgaggatatt accaaagcgc catctggtat gactggctta gaaacatccc tgtctctcag
     5041 cttgacctat ttaatagaag ctggtgagtt gagcttgatg gaattacttg aaaaaatgac
     5101 atacaaccca gccaagcttt acaactttga agcaggttac ttggctgaga atggtccagc
     5161 agatatcact atttttgatg ccaaggctga ccgctttgtg gactcccatt ttgcttccaa
     5221 agcagctaat tcaccattca tcggtgaaac cttaaaaggg caggttaaat ataccatctg
     5281 taagggacaa atcgtctatc aagcttgata ggagttagaa tatgaattat tttcgaaaac
     5341 gtagggagag acaagcgaaa tctaatagtg gaatttactg tcccgcagct aatcgttcca
     5401 aaattcaata tgaaactaaa gaaaaagctg accatgcggt tcaatatgat aacggaggtt
     5461 tagttagaag ctattattgt cgtacatgtg cgtgttggca tactacttca aaatctaata
     5521 aacctccgct aagtttgaaa aactatggtc tgaaactctt tggtttagat aaatcagaat
     5581 agaaagagaa gtatgtataa gacaaagtgt ttacgagaga agttagtatt atttttaaaa
     5641 attttcttcc caatcctgat ctaccaattt gccaattatt ctgcctcttt tgttgatact
     5701 gcaatgacag gtcaatacaa cactatggac ttggctggtg tatctatggc aaccagtatc
     5761 tggaatcctt tctttacatt tctaacaggg attgtgtcag ccttggtgcc tatcattggt
     5821 caccatcttg gtcgaggcaa aaaggaagaa gttgcgtctg atttttacca atttatttat
     5881 ttggccttgg gcctatctgt ggtcttgctg gggatggtac ttttcttggc accaataatc
     5941 ttgaatcata ttgggttaga agcagcagta gcggcagtag cggttcgcta tctttggttt
     6001 ttatctatcg ggattatccc cttgttgctc tttagcgtca ttcgttcctt gctggattcg
     6061 ctgggcttga ccaaactgtc catgtacctc atgcttttgt tactccctct caatagcgga
     6121 tttaactatc tcttgattta cggtgccttt ggtgttccag aactgggagg ggctggtgct
     6181 ggtttaggaa catccttggc ctactgggtc ttgcttggga tttctgttct ggttttattt
     6241 aaacaggaga agctcaaagc cttacacctt gagaaacgaa ttccacttaa tatggataaa
     6301 attaaggaag gagttcgttt aggtctgcct attgggggaa ctgtcttcgc ggaagtggct
     6361 atcttttcag tggttggctt gattatggct aagttttcgc ccttgattat agctagtcac
     6421 cagtcagcta tgaacttttc aagtcttatg tacgcctttc ctatgagtat ctcatcggct
     6481 atggctattg tcgtttccta tgaagtggga gccaagcgat ttgatgatgc gaaaacctat
     6541 attggtctag gaagatggac tgccctcatt tttgcggcct tcaccttaac cttcctttac
     6601 atttttaggg gaaatgtggc cagtctttat ggtaacgacc caaaatttat cgatttgaca
     6661 gtgcgttttt taacttatag tcttttcttc cagttagcag atacctttgc ggcgccgctt
     6721 cagggaattt tgcgggggta taaggataca gttattcctt tttaccttgg tttgcttggt
     6781 tattggggcg tagcaatccc tgtggctacg ctatttgatt ccctaacaga ttttggagct
     6841 tattcttact ggatcggctt gattattagt ttgattgtga gcggggcgct ctaccgttgg
     6901 cgtttaactg tgattatgaa gagatttgaa tctttagcaa aatccaaatg ctaaaaagtt
     6961 tgtgaaaaaa tattcttgac aagaaaatcc cttgttttca cggggttttc ttttttattt
     7021 tgtgaaattt cttttagaaa aactttgaca gtatttgcca aaagcggtaa aatagtaagg
     7081 taagaagaaa gttagaaagg caagaagatg tcaactttag ataaaaatct tttgctagaa
     7141 atgttccgta agatggaaga aatccgtcgc atggacttaa aaattgcaca attagtaaag
     7201 aaagggaaag tgccaggaat gacgcacttt tctgttggtg aagaggcagc taacgtgggg
     7261 gctatgttag ctctcaatcc agatgatctg attacctcaa accaccgtgg acacgggcaa
     7321 gctattgcta aagggattga cctcaacgga atgatggctg aaatccttgg taaatacact
     7381 ggaacctgta aagggaaagg tggatctatg catatcgctg accttgatgc tgggaacctt
     7441 ggtgccaatg gtatcgtagg tggtggtatg gggatcgctg tcggtgcagc cctcagtcag
     7501 caaatgcaaa ataccggtaa aatcgttgtc tgcttctttg gagatggtgc gaccaatgaa
     7561 ggtgttttcc acgaagcagt gaacatggct tctatctgga acctgccagt cattttctat
     7621 tgcattaaca acggttacgg tatctctgcg gatatcaaga aaatgaccaa tatagaacat
     7681 atccatcaac gtagcgccgc ttatggaatt cctggaatgt tcatcgaaga cggtaacaat
     7741 gtcatcgatg tctatgaagg atttcagaaa gctgtggacc atgttcgcag tggcaatggt
     7801 ccagtcttga ttgaaagtgt aacttatcgc tggctcggtc actcatcatc tgaccctggt
     7861 aaatatcgta cgcgtgaaga agtggaattg tggaaacaaa aagatccaat cgaaaacctc
     7921 cgcaattacc ttattgaaaa taacattgca agtgccgaag aattggaaga aatccaagcg
     7981 caagtaaagg aagcagtaga agcttctgtt aaatttgcag aggaaagccc attcccaccg
     8041 cttgaatcag cctttgaaga tatttacgca gactaaggag aaagagataa aatggaaaca
     8101 aaaacaatgt ccttccgtga caccattatc cttgctatgt ctgaggaaat gcgtcgcgat
     8161 gaaaatgtgt tcttgatggg agaagacgtc ggtgtcttcg gaggagactt cggtacttct
     8221 gttggaatgc ttgaagaatt tggtccagaa cgtgtccgtg actgtccgat ttctgaagct
     8281 gccatctctg gagcagcagc aggagcagcc atgacaggac ttcgtccaat cgtcgatatg
     8341 accttcatgg acttctctgt tattgccatg gacaatatcg tcaaccaagc tgctaaaaca
     8401 cgttacatgt ttggtggtaa aggtcaggtt ccaatgactg ttcgttgtgc agctggtaac
     8461 ggagttggct ctgccgccca gcactcacaa tctctagagt cttggtttac tcacattcca
     8521 ggacttaagg ttgtggcacc tggaacacct gcggacatga aaggcctgct taagtcttct
     8581 atccgtgata acaacccagt tattatactt gagtacaagt cagaatttaa ccaaaaaggg
     8641 gaagtgccag ttgatccaga ctacacaatt ccacttgggg ttggtgaaat caaacgccaa
     8701 ggaacggatg taacagttgt tacttatgga aaaatgcttc gccgtgtggt tcaagctgct
     8761 gaagaattag cagaagaagg aatttcagtt gaaattgttg acccacgtac ccttgttccg
     8821 cttgataagg atatcatcat aaactcagtg aagaagactg gtaaggttgt tctggtcaac
     8881 gatgcccaca aaacaagtgg ctatatcggt gaaatttcag ctattatttc agaatcagaa
     8941 gcatttgact atctagatgc accaattcgc cgttgtgcag gagaagatgt gccgatgcct
     9001 tatgcacaaa acctagaaaa tgcaatgatt ccaacagttg aaagtatcaa agatgcaatc
     9061 cgaaaaactt ataacaaaga atagggttac ataagataag ttatgtaaat aaaataaagc
     9121 tgacgagaaa ctttgtatct tttaggtgca gagctcttcg tcattaatat cttagattag
     9181 agcacgggct aaaagatcgg aaaaaagata aatctccttg gcttcatcga agccatcgtc
     9241 gatttcctat ttttcagtcg cttttgacgc cctttgtatc ataaatagaa ttggagaggt
     9301 catggctgat gacaagctaa gagcgactcc tgcagctaga aagttagcgg atgatttagg
     9361 gataaacctc tacgacgttt ctggctcagg tgcaaacggt cgtgtccaca aagaagacgt
     9421 ggaaacttat aaagacacaa acgtggttcg catttcgcca cttgcaaaac gaattgccct
     9481 cgaacataac attgcttggc aggaaatcca aggaaccggt catcgtggta aaatcatgaa
     9541 gaaggatgtt ttggccctgc ttcctgaaaa tatcgaaaac gatagcatca aatctcctgc
     9601 tcagattgaa aaagtggaag aagtccctga taacgtaaca ccatatggta aaatcgagcg
     9661 tattccaatg acaccaatgc gtaaggttat tgcccaacgc atggttgaat cttacttgac
     9721 tgcgccaacc ttcaccctca actatgaagt tgatatgact gaaatgttgg ctcttcgtaa
     9781 gaaggttctt gagccaatca tggaagcaac tgggaagaag actactgtaa cagaccttct
     9841 ttcgcttgca gttgttaaga ctcttatgaa acacccatac atcaacgctt cattgacaga
     9901 agatggcaag actattatca ctcacaacta tgtcaatctt gccatggcag ttgggatgga
     9961 taatggattg atgacacctg ttgtttacaa tgctgagaag atgagtcttt cagaactggt
    10021 tgtagccttt aaggatgtta ttggccgtac cttggatggt aaattggctc caagtgagtt
    10081 acaaaattca acattcacaa tcagtaattt gggaatgttt ggtgttcagt cctttggtcc
    10141 gattattaac caacccaact cagctatcct tggtgtcagt tcgacaatcg agaagccagt
    10201 tgtcgtcaat ggtgaaattg tgattcgccc aatcatgagt ttaggattaa ccattgacca
    10261 ccgtgtcgta gatggtatgg ctggtgctaa gtttatgaag gacttgaaag agttgattga
    10321 aacgccaatc tcaatgttaa tttaagagca agagtattca tttttaagat atagataaag
    10381 gaaggaagac atggccttag aagtaattat gccaaaagcc ggcgtggata tgacagaagg
    10441 acaaatcgtc caatggaata aaaaagtcgg agaatttgta aaagaaggag aaatcctttt
    10501 ggaaatcatg actgataaag tcagcatgga attggaagcc gaagaagatg ggtacttgat
    10561 tgccattctc aaaggagatg gtgaaactgt ccctgtaacg gaagttatcg gttaccttgg
    10621 tgaagaaagg gaaaacatcc caacagctgg agcagcatcg ccagaagcta gccctgtacc
    10681 tgtagcaagt acctcaaacg atgatggtaa gagcgatgat gcttttgata tcgttgtgat
    10741 tggtggaggt cctgctggtt atgttgcagc cattaaagct gcccaactcg gcggtaaggt
    10801 tgcccttgtt gagaaatctg aacttggtgg aacctgctta aaccgtggat gtattccaac
    10861 caagacctac cttcataacg ctgaaattat tgaaaatatc ggtcatgctg caaatcgtgg
    10921 tatcgtgatt gaaaatccta acttcactgt tgatatggaa aaacttttag aaactaaatc
    10981 taaagttgtt aatactcttg ttggtggtgt tgcaggactt cttcgtagct acggagttac
    11041 tgttcataaa ggaattggta caatcactaa agacaagaac gtcttggtaa atggctctga
    11101 attgcttgaa accaagaaaa tcattcttgc tggtggttca aaagtcagca agatcaatgt
    11161 ccctggtatg gaatctccac ttgtcatgac tagtgatgac attcttgaaa tgaacgaagt
    11221 gccagaaagc cttgttatca tcggtggtgg agttgtcggt atcgaactcg gtcaggcctt
    11281 catgacattt ggttcaaaag tgactgttat cgaaatgatg gaccgtatag ttccagctat
    11341 ggatgcggaa gtttctaaga accttcgctt gatccttgag cgtaaaggaa tgaccatctt
    11401 gactggtact aaactgcaag aaatcattga ggaaaatggt caacttcgta tcaaggttga
    11461 aggaaaagac gatatcatcg caagcaaagc tcttctttca attggtcgta tgccagacct
    11521 tgaaggtatt ggagaggttg agtttgaatt ggatcgtggt tgtatcaagg tcaatgaata
    11581 catggaaact tcagttccag gcatttatgc accaggtgac atcaacggta ctaagatgtt
    11641 ggctcacgca gctttccgca tgggtgaagt ttccgctgaa aatgccctta aaggaaatca
    11701 tgcagttgcc aaattgaatt tgactcctgc agccatctac actctccctg aagtagcagc
    11761 agtaggtttg acagaagaac aagcccgtga gaaatacgat gttgccatcg gtaagtttaa
    11821 ctttgctgct aacggtcgtg ctattgcatc tgacgcagct caaggtttcg taaaagttat
    11881 cgctgataag aaatacggag aaatccttgg tgtacacatt attggtcctg cagccgcaga
    11941 attaataaac gaagcatcaa gcatcatcga aatggaaatc actgttgagg aaatgctgaa
    12001 gaccatccac gggcacccaa cttactctga agtgatgtac gaagcgtttg cagatgttct
    12061 aggaatggcc atccattcac ctaagaaaaa ataaaacgaa gatagattag actggaaggt
    12121 tatttccagt ctctatcata taaagtaaag ggatatcatg aaatacatta tcaatcattc
    12181 aaatgacact gcttttaata ttgccttgga agaatacgcc tttaaacacc ttttggatga
    12241 ggatcaaatc ttcctacttt ggattaacaa gccatctatc attgttggtc gtcaccagaa
    12301 cactatcgaa gaaatcaacc gtgattatgt tcgcgaaaat ggtattgagg tagttcgccg
    12361 tattagtggt ggtggagctg tttaccacga tttaaataac ctcaactaca cgatcatctc
    12421 caaagaagat gaaaataagg catttgactt caagagcttc tcaactccgg ttatcaatac
    12481 cctggctcaa cttggggtta aagctgagtt cacaggtcgt aatgaccttg agattgatgg
    12541 taagaagttc tgtggcaatg cccaagccta tatcaacggc cgtatcatgc accacggttg
    12601 cttgctcttt gacgttgatt tgtcagtcct cgcaaatgcc cttaaggttt caaaagataa
    12661 atttgaatca aaaggtgtga aatccgtccg tgcccgtgta accaatatta tcaatgaatt
    12721 accaaaaaaa atcacagtcg aaaaattccg tgatttactc ctggaataca tgaaaaaaga
    12781 gtacccagag atgactgaat acgtcttttc agaagaagaa ttggccgaaa tcaatcacat
    12841 caaggatact aagtttggaa cttgggactg gaactatggt aaatcacctg aatttaacgt
    12901 ccgtcgtgga accaaattca ctagtggtaa ggttgaagtc tttgctaacg ttactgaatc
    12961 aaaaatccaa gacatcaaga tttatggtga cttctttggt attgaagacg ttgctgcagt
    13021 agaagatgtc cttcgtgggg tgaaatacga acgcgaagat gttcttaagg cgctaaaaac
    13081 cattgatatc acacgctact tcgctggtat tagccgtgaa gaaatcgctg aagcggtagt
    13141 tggataaatc aaaaaaagaa gttagccaac ttcttttttt gatatttatt tacataattt
    13201 aaaatacgta aaatcataaa ctatctagag cattcttttg ttcatcatta acaatatggg
    13261 tatagaggtc agtgacttgt gtgctggcat gtcctagttg gtgactgact aaaacttgtg
    13321 atttagtcgc atcatagagc ctagttgcta gcgtatggcg cagtttatgg ggtgttacac
    13381 gcactttaaa atcctctgag tatttagcaa ccattttctc aacgctagaa gcatcgatac
    13441 gattaggaac acctctgtag agagttaaaa aaagggctgt atctgttttt tccgttttat
    13501 agcgttgatt ccgaatggcc agataattct ctaaataagg tttagcaaaa gcagcgacat
    13561 tgactgagtc acgtttgcca ccttttcgag taacatcaat aaccatcatt tttagattga
    13621 gatctcttag atctagatta acagcttcag ataagcgaac accagatgcc aagagaaggg
    13681 caataatggc taaatctcgt tctttatttt tgttgaatga tgagagagct cgatttgaaa
    13741 gctgttgtgg gtgctcttga tcgatataag ttagaaaacc ttctgtttca tcacctagaa
    13801 agagtttttg cttgatattt tcagctctgg cagcaagggt ttctttcttt ttcttggttg
    13861 aaactttttt cattacatta cgatagaaat aaggttcccc ctgatcgttt tcaacctcct
    13921 cggttagata cttgtaaaga ctagaaagtg ctgataaggt tcgattgata gttgtctgtg
    13981 aaacaccttg ttttgttgta ttagcattca gcaagggacg ttcacgtaga taaaggataa
    14041 aggattccat gtctttctta gacatatttt ccaaaactga taaaggaata tcggatattt
    14101 tatcagcgtt tgaaatacca gactccaaaa cccagctgaa aaatcggtca tattccttaa
    14161 ggtattcgta cagggttgta aaactgtagg gcacagccag cttagattgg tagtattcca
    14221 gaacatacca gggcatgagt tgttttagtt tgtcgattcg ttccagtaaa atctcacgtt
    14281 tcatgtattt tctccataag taagtatact agtagtatag catagacttg tatatttttc
    14341 aagaaaatta tagtttttct gaaagatgtt ataggagttt ttcaaagtga taaaaagact
    14401 tagacctaca aacaaaacag aataaggaaa ataataaaaa tctcacccac taaacttctg
    14461 ttaatactac ataactgaag agctatataa ggagctatga gatacaaaac acattgtata
    14521 atagattgaa actagaatag tacatctgaa cttctaaaac attgctagaa attgatttga
    14581 ttgtcctgat tgttttatcc tatttctatt tcatttcact atataattgc tattgttttc
    14641 tttttcatga ttttaatctt actgtacaga tttgatacag taaactcctt tctagcttta
    14701 tactttatca tttctaactt aattatagtc ttatttttaa taaagttcaa ttatttatat
    14761 gtaaaattcc tcatcagtaa aaaataaccg atctcatttc tgagaatcgg ttttctaaat
    14821 aaatcaagcc aatcatttac ataatataaa ttatgtaaat gattgtacta caacaacaaa
    14881 tctttgactt ttccaatttc actttttgga ataaccaggt gaatcatatc acccagatac
    14941 attctggttg agccgttaac tgtttggctc ttgccattat ggacttgagt tgtgatgagg
    15001 acgttgtgtg gtaagttgag ttcatgaact tgtttcccag caattttatc agaaactggt
    15061 atttcgataa gtgtaacttc tccttcgcta gatacttctt ctggaagcat tttttccagc
    15121 atggcttcat agactggcgt acctttgagc aaatccatga taatataaga aacaagagtg
    15181 acaagaccaa gtggcatgag gttgcgaata tctcctacca tctcagttac gaggatcata
    15241 gcggttaagg gagcttttga tatggctcca aaatagccac tcattcctag aatgacaaat
    15301 atagggaatt gctcttgact gacaagtcta agattgacac agataacacc aattaaggca
    15361 ccaagcaaag aaccaagagc taaaatgggg aggaaaattc ctcctggcag tccacttcca
    15421 tagctaatca tactccaaat aaagcggatc aaaaagtaag ctaataaaac ttggaaacta
    15481 aaattttgtt cagttaaaga aaggacaagc tgatttccgc caccaatgat ttgaggtaag
    15541 aagattccga ctggtatgat aaggataaaa gccaagatgg gataataagc tctatccaaa
    15601 tggatttttt gaccaatcaa gtcataaact cttccaacgt ttaatacagc tttctcatag
    15661 agaaagcctg aaaatccaag gaaaattccc atgacgagat atatccaata ctgatctagg
    15721 gtcatgggag gaatgttatc tggcatatcc aatactggtg tcaaaccgaa catgagtaga
    15781 gacacaaagt ttgctacgat gctggctgct agagttgaga cccagaaaaa gcgcgaaaaa
    15841 tggtgataga cttcttctac aacaaagaga agtgctgcaa taggagcatt aaaggctgcg
    15901 gctaaacctg ctgcagctcc actggcaatc aaggaacgtt cctctactgg actggatttg
    15961 agccacttgg caattccttt accaccaact gctccaagtt gaatactggg tccctctcga
    16021 cccagcatga gtccactggc aatagcgaga atacctagca catatttttt ccaaagaatg
    16081 ccccaccagt tgagggacat gaggcctttc agttcggctt cgacttgagg aattcctgag
    16141 cctttaatat ctttttctga ccgtgttagt ttggcactga gccaacagat gagtatataa
    16201 aacaaaacca gtacaaaaag attgcgcact aagtaccctt gatcttgata aactccttgt
    16261 atcatgtgga agcccttttc aattaagaaa cgaaaggatc cgacgataat tccaacgatg
    16321 aggccgacaa tgattcctcg accaacttgg gatagtatag tgctggatgc aaaggcgaat
    16381 tctttcttag aacggactat ttccgactgt tcctccatgg tatttccttt caattaactt
    16441 tcttttttac ctaaaaccag tgatttaacg ggttcaaagc tggttcggtg aattggggta
    16501 actcctagtt ttgtgaggcc ttccagatgt ttagctgtgc catatcctgc attagtagcg
    16561 aaatcatagc cagggaactg ctgatcgtat tctttcatca attcatcacg tgttaccttg
    16621 gctactatag atgctgctgc gatagagagg gagttggcat ctcctttgat aatggaggtt
    16681 tgtgaaatgg gcaagtccag tttcatggca tcaatcaaaa ggtgctctgg ttgagggctg
    16741 agctgggaga ttgcttcttg catggctagt ttggttgctt catagatgtt gacttggtcg
    16801 atgacctgat tatctatgat accaattcca atcgacaagg cttggtcttg aacggcttgg
    16861 aaaatctcca gatgtttctt tttaggaatt ttcttgctgt cgttgagacc tttaatctta
    16921 caatttttag gtaaaataac ggccgcagcg actacaggac cagcaagagg accacgacca
    16981 acctcatcaa tacctgcaat taaggtcaat ccttgcttat aaagttcttt ttcataagaa
    17041 agcatggatt ccaagcgcaa attttcatct aattcagctt ggatggctct tttacgcttg
    17101 ctgatttcct tttgaactcc tgagcgatta tccttttcaa gctctaaaaa aatagggctt
    17161 tctaactcct tgactgtcac aaggagttct ttgatttctt taatcgttgc catcgaggtc
    17221 ttccaatgta tctaaggtat agttaccgag tttgccatca cggacttcct tcacgaagag
    17281 actgtaaaaa cggtcatagt catcacggaa accgagggcg cgggtcatat ccataataat
    17341 cacagacggt tcttcttcaa ttttcatttg tttgaagcgt tcagccagct tttctggata
    17401 atgttctttg aaataattga taccaaaaat ggtaacctca tccataggaa gcaactggtc
    17461 tttgatagct ccagtcaatg ccaacttaag tgcaacagtt tcatcctcaa acttaggcca
    17521 gagaatcccc ggtgtatcca agatttccag gtctttattg gttttaagcc attgttgacc
    17581 ttttgtgacc cctggcttgt ttccaacaac agcaatcttt ttaccagcca aacggttcat
    17641 cagagttgat ttaccagcgt ttggaatccc gataatcatg gtacgcaagg tttcaatctg
    17701 aatcccacgt tctttctggc gagcaatctt atcagccatg agcttcttgg ccgcatctgt
    17761 tacaactttt acagtcactt gctctttgga gttgatagct agcgtctgga ttccttgtga
    17821 ttcaaaatac tgacgccatt ccttggtcat tgctggatca gccaagtcgg ccttgtttaa
    17881 aatcaagagt tttggtttat caccaacaat cttggtcaac ataggatttt gactagatag
    17941 aggcaagcgt gcatctacta aaatcgtcac aaaatcaaca aattttaaat tctcctgcac
    18001 ctgtcgacga gctttagaca tgtgaccagg aaaccattga atagtagcca ttgagttttt
    18061 tcctttcgta gctctgaagc tgttaatcta gaactaagag atctcaatct aaaaatgaat
    18121 gatgtccaaa cagttcttgt tttatgacat aaaaatctac tttatattat atcatgcctt
    18181 ctttattttg tccgatgata gccttttacc ctatatagaa aaaagccatc aaatgatgac
    18241 ttttcagagg gagcaaaaaa ctgtcctctt tatgttttaa ac
//
LOCUS       DAVHSH010000037        18143 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000037 DAVHSH010000000
VERSION     DAVHSH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.037"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            308..628
                     /locus_tag="VVR08_001419"
     CDS             308..628
                     /locus_tag="VVR08_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6075325.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(681..1268)
                     /locus_tag="VVR08_001420"
     CDS             complement(681..1268)
                     /locus_tag="VVR08_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6075326.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            1510..2181
                     /gene="sdaAB"
                     /locus_tag="VVR08_001421"
     CDS             1510..2181
                     /gene="sdaAB"
                     /locus_tag="VVR08_001421"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU6075327.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2190..3062
                     /gene="sdaAA"
                     /locus_tag="VVR08_001422"
     CDS             2190..3062
                     /gene="sdaAA"
                     /locus_tag="VVR08_001422"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU6075328.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            3084..3716
                     /locus_tag="VVR08_001423"
     CDS             3084..3716
                     /locus_tag="VVR08_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6075329.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            3766..3948
                     /locus_tag="VVR08_001424"
     CDS             3766..3948
                     /locus_tag="VVR08_001424"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075330.1"
                     /translation="MKIKEQTRKLSATSKHCFEVVDRTDEVSNHTYGKATLTWFEEIF
                     EEYKSLHNKTHITKVV"
     gene            complement(3973..5823)
                     /locus_tag="VVR08_001425"
     CDS             complement(3973..5823)
                     /locus_tag="VVR08_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6075331.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5865..7022)
                     /locus_tag="VVR08_001426"
     CDS             complement(5865..7022)
                     /locus_tag="VVR08_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6075332.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINKNML"
     gene            7080..8246
                     /locus_tag="VVR08_001427"
     CDS             7080..8246
                     /locus_tag="VVR08_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU6075333.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            8385..8711
                     /locus_tag="VVR08_001428"
     CDS             8385..8711
                     /locus_tag="VVR08_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6075334.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            8698..9291
                     /locus_tag="VVR08_001429"
     CDS             8698..9291
                     /locus_tag="VVR08_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU6075335.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            9284..10195
                     /locus_tag="VVR08_001430"
     CDS             9284..10195
                     /locus_tag="VVR08_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU6075336.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            10258..11322
                     /locus_tag="VVR08_001431"
     CDS             10258..11322
                     /locus_tag="VVR08_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075337.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLYVISIGIILLASLHIITRPSQASETDAFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11394..12254)
                     /locus_tag="VVR08_001432"
     CDS             complement(11394..12254)
                     /locus_tag="VVR08_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU6075338.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQANIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRVVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPRESFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQLEIQPTLG
                     QDFKTLAQEK"
     gene            complement(12529..13515)
                     /locus_tag="VVR08_001433"
     CDS             complement(12529..13515)
                     /locus_tag="VVR08_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU6075339.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEGLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13787..15262)
                     /locus_tag="VVR08_001434"
     CDS             complement(13787..15262)
                     /locus_tag="VVR08_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU6075340.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(15472..16395)
                     /locus_tag="VVR08_001435"
     CDS             complement(15472..16395)
                     /locus_tag="VVR08_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6075341.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(16409..17338)
                     /locus_tag="VVR08_001436"
     CDS             complement(16409..17338)
                     /locus_tag="VVR08_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6075342.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(17657..18007)
                     /locus_tag="VVR08_001437"
     CDS             complement(17657..18007)
                     /locus_tag="VVR08_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075343.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         5395 a         3906 c         3390 g         5452 t
ORIGIN      
        1 actttttctc ctatctttat tttctaccta catagtacct cttattaagc tcattttaaa
       61 attacgttaa cttttttcac gaaaaggaga aaattatgcg ttattatgga tagcgctttc
      121 aaatttttaa actcctatcc cgtcctttta tctatataat aagcataagc gaaaatataa
      181 taactgtcaa gtatctgaag tgaattttat aaaaaaatta caagccaaat ttgtaaagtt
      241 tacactaagc cgctagggca atcgtctatc agaatgtccg tttatttgtc aataatccga
      301 gaaaatcttg caacgcttag aagtctataa aaactatcaa catttatatg acttgcgaat
      361 agcaatcctg ctcaaccttt ccacactcta tctatacaat caagataaaa acatgtgtaa
      421 gcaaatctgc tacactttac tagaggacgc caagaataag aaaagctacg ataggctggc
      481 tatctgctat gtccgtattg ggatttgtac agacgattct aaacttatcc aaaaaggttt
      541 ctcactccta gagctgaccg aggaaacttc tatgctgtct catctcaaaa aagaagtaga
      601 gacccattat caaccaaaga aattataaaa aaagtcgagg gatttcctcg actctttaca
      661 tattatttgt tcgttagttc ttaataccag ccattgttaa gccagaagtt tttagcagct
      721 gtccatgaac cgtaacgtcc tgcaacgtag gcatctgcta cacgttcttg gttttcagct
      781 gagtagtcac cgttcaggta tgaatctgtt aattggtaac gtccgatata acgtccattt
      841 gtagctgtat agctaccacc tgattctttt tgagcgatcc attctttggc ttctgcttca
      901 gatccgctta cagttgaaac aactgtttca cttactactg gagtttctgc cactggagct
      961 gaaacagttt catcttgagc ggctggtgcc gcataagtag ctggcgctgg tgttgcaaca
     1021 ggcgctacag ggccatcgat aaccaactct tgaccaacat aaatcaaatg aatgttatca
     1081 atgtggttgt tttctgccaa tttttcaact gttgtgttgt gagtttcagc gatttctgaa
     1141 agtgtatcac cttctttaac tgtgtaagtt gatgattctt gagcagatac aaatgatgga
     1201 gcaaatactg caaacaaggc agctactcct gcaagagttg ctttaatctt tttagttatt
     1261 gatttcatat tcgaaaattc tccttctttc tatagttcta tcataccctt taaatattac
     1321 cgtttcttga cacttttatg tagaaatatt acaaaattat tttttatttc cctaaataag
     1381 gtgttttttg tcataaaaga tactattttt atgctatttg aggtattaga aaggttttca
     1441 tccacaatta aagccaagcc cctcattctt tgatataata gagataagaa tttttataag
     1501 gggaaactga tgaaatcact tcgttttcaa tctgtctttg atatcatcgg accagttatg
     1561 attggcccat ctagtagcca taccgctggt gctgttcgta ttgggaagat tgtctcttcc
     1621 atttttgatg atactccgac agaagttgaa ttccaacttt ttaactcatt tgccaagacc
     1681 tatcgtggtc acggaacaga cctagccctt gttgcaggta ttttgggaat ggatacagat
     1741 gatcctgaaa ttccaaatag tctggaaatt gcccacaagc gtggtatcaa gattgtctgg
     1801 accattcaga aagacagcaa tgcccctcac cctaacacca ctaaaattac tgttaaaaat
     1861 gcccacaaga ccatcagcgt gactggtatt tctatcggtg gaggaaatat tcaggtaacc
     1921 gaactcaatg gttttgccgt ctctctcaat atgaatacac cgactatcat catcgttcat
     1981 caagatattc caggtatgat tgcccttgtt acagaggcgc tttcccgcta tggtatcaat
     2041 atcgcccaga tgaatgtcac tcgtgaaaaa gctggtgaaa aagccattat gattatcgaa
     2101 gttgacagtc gcaactgtga tgaggctatc gaagaaattc gaaaaatccc tcatctccac
     2161 aatgtcaatt tctttaaata ggaggaagca tgttttattc tatcaaagaa ttggtcgagc
     2221 aagcagatct ggactttcaa ggaaatgtcg cagaactcat gattacaaca gagtttgaat
     2281 tgaccggtcg cgaacgtgaa gaagtcttcc ttctcatgga acgcaatctg gaagttatga
     2341 aagcctctgt ccaacttggc ctcaatgaaa ataaatctcg tagtggcctg acaggtggag
     2401 atgctgccaa attggatcac tacatcgaaa acggaaaaac tctgtcagat tatacgattc
     2461 tctcggctgc ccgaaatgcc atcgcagtta atgaacacaa tgccaaaatg ggcttggtct
     2521 gtgccactcc aaccgctgga agtgctggct gtctgccatc cgttctcact gctgctattg
     2581 aaaaattaga cctcagccac gagcaacaat tggatttcct ctttgctgct ggtgcctttg
     2641 gactagtcat cgcaaacaat gcctccatct caggtgctga gggtgggtgt caagctgaag
     2701 ttggttcagc ctctgctatg agtgctgccg ccttgactct ggctgcaggt ggaacacctt
     2761 atcaggccag tcaagctatt gcctttgtca ttaaaaatat gctaggcctc atctgtgacc
     2821 ctgttgcagg tttggtcgaa gttccctgtg tcaaacgtaa tgccatggga gctagctttg
     2881 ctttcatcgc agcagacatg gccttggcag gtatcgaatc taaaatccct gtggatgaag
     2941 tgatcgatgc catgtaccaa gtaggagcaa gcatgccaac tgcctttcgt gaaacagctg
     3001 aaggtggact cgctaccacc cctactggtc gtcgcctcca aaaagaaatt ttcggagaat
     3061 aagcttatca aataggagaa accatgacct ctatcacagc gatttttttc gatttggatg
     3121 gaaccctcgt tgatagttct atcgggattc acaatgcctt tacctatacc tttaaagagc
     3181 tgggggtgcc tagccctgat gccaaaacta ttcgtggttt tatgggacca cctctcgaaa
     3241 gtagttttgc gacctgcctg tccaaagacc aaatttctga agccgtgcag atatatcgtt
     3301 cttactataa ggcaaaaggc atctatgaag ctcaactctt tcctcagatt atagacttgc
     3361 ttgaggagtt atcgagcagt tatccactct acatcaccac gacaaaggat acatctactg
     3421 ctcaagacat ggcaaaaaac ttggaaatcc atcatttctt tgatggcatt tatggttcta
     3481 gccctgaagc accccataag gcagatgtca ttcaccaagc cttgcagaca catcaactag
     3541 caccagaaca agccatcatc atcggagata ccaagtttga tatgctggga gctcgagaaa
     3601 caggtattca gaaattggcc atcacttggg gatttggaga gcaagcagat ctactaaact
     3661 atcaacctga ttatatcgct cacaaaccct tagaagtttt ggcgtatttt caatagcata
     3721 gactgggtaa caattccatt tcagaagaaa atgaagtaat actcaatgaa aatcaaagag
     3781 caaactagga aactatctgc aacctcaaaa cactgttttg aggttgtgga tagaactgac
     3841 gaagtcagta accataccta cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa
     3901 gagtataagt ctctacataa taaaacgcat attaccaagg ttgtgtaact tgatactatg
     3961 cgtttttctt ttttattcaa tgtgggttgt ttgattagca aaggcgataa tagcttgctt
     4021 caactcatct ccactgagag tgcggaactc tccaatcttt tgattgatgg attctaaagg
     4081 catgacatta accttaccaa cgaaaatctt atccataact tgattatcaa cgagttcggt
     4141 tgataccaag agttcttcgt agagtttttc acctgggcgg attccaactt caacgattgg
     4201 aatttcactt tcagtgtggc cacttagaag caccatcttc ttggccaagt cataaatctt
     4261 gactggtttg cccatatcaa ggataaagac ttccccatct ttggcataag caccagcatg
     4321 gataaccaga cggctagctt ctggaatggt cataaagtaa cgggtcatgc ggaagtctgt
     4381 caccgttaca ggcccacctt cagcaatctg acgttcaaag actggaatga cactaccacg
     4441 gctaccaaga acattcccaa aacgaactgc acagtaggtt gattggctac gttggttaaa
     4501 gccagtgaca atcaactccg ccacgcgctt ggttgctccc ataacatttg gtggattgac
     4561 tgccttatct gtcgaaatca taaccatctt agacacttta gcttcatcaa cagccttagc
     4621 aacattgtaa gttccacgga tattgttttt gaaggcttct tttggattgc gctccatcat
     4681 aggaacatgc ttgtgggctg ccgcatgata aacaatagca ggtttgtact gctcaaagac
     4741 ttgcaacaaa cgatcatagt cttgaatgtc cgcaatcaca ggtacataat caatcccttg
     4801 gaacttacga atcaattcat gataaacaag gtagattgag ttttccccat gaccgagcaa
     4861 gacaatgcgt tcaggattga agcgactaac ttgacgacag atttcagaac cgattgaacc
     4921 tccagctcct gtgactaaga tggtcttacc tgtcagttct gcacccagac gcgattcgtc
     4981 aagacggatt tcctgacgac ccaaaaggtc cgtaatatca attttttgga agccagtacc
     5041 tgcttggtga aggccctgaa caacagtttc aaccttaggc atcttgtaac atttgacacc
     5101 cagcttatta cacatctgca agatacgctc atattctgac ggatccagcg acggaatcgc
     5161 aacgatgaca cgctcgattt gatggcgttt ggctaattca ggcagattgt cataagagcc
     5221 caaaacagga ataccaccaa gtttttgacc ctttttctta gaatccttat ccaaaatacc
     5281 gaccagttct aattcactgg ttggatgttg gtaactatcc ataaaaagag ccccaccatc
     5341 accggcacca atcaagaagg tccgacggtg ttctccatca ccactacctt ttttgcgtct
     5401 ggagtagatt aactgccaag taatccgtgg caataaaatc aagaaggtac tcaacaagat
     5461 aaagagaatg atgaaacgga tggagaagag tggcaagaag gcataacaga tactatatga
     5521 caagacactg ctggcagtca caccaaaaaa gattttcatg aaatccgtaa tcttgctgta
     5581 acgactaata ctagcgttca acccccaaaa accaatcatc aattgataga acaggaaggc
     5641 caaactcgta tagataatgt agtcaacagg tgctggatta atcaagccgt agaataagat
     5701 ataagataca atgatggaaa ccaccatact gaaaatatca aatattcccc agaaaacctg
     5761 cttttgttgt ttatttaaaa tttccaccag atcaatcaca taatctgtta gttttttatt
     5821 catagaaatc tactcctcct taaaagagtt ttactatatt gttattatag catattttta
     5881 tttatttggc ttattttatc caaataaatt attgttccct tgtactcctt cttccattta
     5941 aatcctctaa ttaaacctac aatcgtccca aggccataag caaagtgaat ggaaaataaa
     6001 agaaagggca tcacaattag aaatccattt ttatgtttta ataaagtcag caaagtgagt
     6061 aatgacaaaa gtagaaaata ggcacctaat agtaaagtta tgaatacgaa tgtgatcggt
     6121 aacaatgcta gactaaacac aagactcaaa acaaataaac aaggaacata gtgaaataat
     6181 gataaacact taaactgaac atgacttgtc aagccaatcc acaaaccatt tgaatacttt
     6241 tgatgcagca ttttcttgaa tgttggtcga atatactgat aagatagaat acttgggcta
     6301 tagcggattt tataaccatg ttctcgaatt ctataatgaa tatcattatc ttcagttcgg
     6361 ccaagttgct catttactaa accaaccttc tggaaaacct ctcgtttata catcccatga
     6421 aaaatagaag aaacatatct atcctcggaa ctatttcgat aattggcaat gctactgcca
     6481 aacatatttt cctcaacaag atgcaaggtc tctgcccatt ttccttttcc ttcgacaatc
     6541 gtcggtctag gccccccaca gacaaattca ccttgttgaa taatagccac attgttcatt
     6601 acaaaactct cagtaacttt tgaatgagca tcaattttta aaataaggtc ccctacagaa
     6661 tgtttaactc ccaggttaaa accactagct tgatttttct taggattgtt atacaatcta
     6721 attgagttaa actctgtatc ttcctttata aattgctgaa tgatagctgt ggtcccatct
     6781 gtggacatag catttataaa tagaatttca atattctctt taggataggt ttgatttttt
     6841 aagtcttcaa ttagaccagg cagatatttt tcttcattgt atgcactgat tacaatggat
     6901 acgagaagac tttcaacatt ttgagtcact actactctcc tgaatttttc cttccaccat
     6961 tctatcataa ttttcaagac tttcccattt ttatcttgaa agccagaaac cttacttgac
     7021 attatagtga aaaagcctta aaataagctg ttattaaaat cagctagaag aggtattata
     7081 tgaaaaagca atcactcttt tttgttccag gtattatcct gattggtgtt tccttgcgaa
     7141 ctccttttac tgttttaccc attattttgg gaaatatttc gcaaggtctg gaggtagaag
     7201 ttagttcgct tggtgtcttg accagcctgc ctctccttat gtttaccctc ttttcaccat
     7261 tttctaccca actggctcag aaaatcggct tggagcatct cttcacctac agcctcttct
     7321 tcttgaccat cggctcactt attcgactaa tcaatctgcc cctgctctat ctaggaacct
     7381 tgatggttgg ggcaagtgtc gcagtcatca atgtcctgct tcctagtctt atccaagcca
     7441 atcaaccaaa gaaaattggt tttctgacca ccttatatgt aacgtctatg gggattgcaa
     7501 cggctctggc ttcctatcta gctgtgccca ttacacaagc cagttcttgg aaaggactta
     7561 tccttctcct cacgttactc tgtctagcaa cttttttggt ctggctccca aatcaccgct
     7621 ataatcatag actagctcca caaaccaaac aaaaaagtca aataaaggtc atgcgtaata
     7681 aacaggtttg ggcaattatt atcttttcag gttttcaatc cttgatcttt tacaccgtca
     7741 tgacctggtt acctaccatg tctatccatg caggtctatc cagtcacgaa gctggcttgc
     7801 tgacttctat cttatctctg attagcattc ctttttcaat gaccatccca agcctgacaa
     7861 ccagtttatc tactcgcaac cgtcagctca tgctcactct ggtttcacta gctggtgtgg
     7921 tcggcatttc catgctcttt ttcccaatca ataatttcat ttactggctt gccatccatc
     7981 tcctcatcgg aaccgcaacc agtgccctct tcccttatct catggtcaac ttttcactca
     8041 agacaagcgc ccctgaaaag acagcccaat tgtccggcct atctcaaaca ggaggctata
     8101 tcctagcagc ctttgggcca accctctttg gttacagttt tgacctgttc cactcttggg
     8161 taccatctgt agctgccctc ttgctcatcg atatcctgat gactgtggcc ctctttacag
     8221 tggacagagc ggataagatc ctttaaactt ctagttttag ctagaagttt tttatatata
     8281 aaaattttac acatttctct tgacagggct ttcttttaga tgtacaatgt atgtgtagaa
     8341 aaattatata taaaaatctt acacattaga aaaggaggtt tcccatgtac tttccaacat
     8401 cctctgcctt gattgaattt ctcatcttgg ccgtactgga gcagggtgat tcttatggtt
     8461 atgagattag ccaaaccatt aagctgatcg ctaatatcaa agaatccaca ctctatccca
     8521 ttctcaaaaa attggaaggc aatagctttc tgacaaccta ttctagagag ttccaaggtc
     8581 gcatgcgcaa atactactcc ttgacaaacg gtggtataga gcagctcttg accctaaaag
     8641 atgaatgggc actctataca gacaccatca atggcatcat agaagggagt atccgccatg
     8701 acaagaactg aatacctgac tcagctagaa ctctatctca agaaactacc tgaagctgac
     8761 cgtatcgaag ccatggacta tttcagagag ctctttgacg atgctggagt cgaaggagaa
     8821 gaagaactca tcgctagttt gggaactccc aaagaagcgg cccacgaagt tctatccaat
     8881 cttctcgata aaaaaatcaa tgaagcaccc gctcaaaaaa ataaccgaca aattttacat
     8941 atcgccttgt tagccctcct tgcagcacct atcggcattc ctctgggaat cgccatcctc
     9001 gtgaccctgt tcgcaatcct tgtagccgct ttgactgtca ttctggcttt ctttgcagtt
     9061 tccatactgg gtatcatcgg cggattccta tttttagttg aaagtttcac tgtcctcgcc
     9121 caagccaaat cagcctttat cttgattttt ggttctggtt tactggctat cggtgcttct
     9181 tcgctagttt tactaggcat ttcctatgta gctcgcttct tcggtctact cattgttcgc
     9241 ctggtacaat ttgttcttaa aaaaagaaag agaggtaacc agcatgcgta aatggacaaa
     9301 aggatttctc atctttggtg tggtgactac cgttatcggc tttatccttc tttttgtagg
     9361 tatccaatct gacgggatta aaagcctact ttccatgtcc aaagaaccta tctatgatag
     9421 ccgtacggaa aagctaacct ttggcaagga agtcgaaaac ctagaaatta ctctccacca
     9481 acacgcgctc accatcacag actctttcga tgatcaaatc cacatttctt accatccatc
     9541 tctttctgct caccatgatc ttatcaccaa tcagaacgat agaactctga gtctcactga
     9601 taagaaactg tctgaaactc cgtttctctc ttctggaatt ggtgggattc ttcatatcgc
     9661 aagtagctac tctagtcgtt ttgaagaagt tattctccag ctaccaaaag ggagaactct
     9721 aaaagggatc aacatctcag ccaatcgcgg acaaaccacc atcataaatg ctagccttga
     9781 aaatgcgacc ctcaatacaa acagctatat cctccgaatt gaaggaagtc gtatcaaaaa
     9841 cagtaaactc acaacgccca atatcgttaa tatctttgat acagttctta cagatagtca
     9901 gctagagtca acagagaatc acttccacgc tgaaaatatc caagtccatg gcaaggttga
     9961 actgactgcc aaagattatc tcagaatcat cctagaccag aaagaaagcc aacgaattaa
    10021 ctgggacatc tcaagcaact atggttctat cttccaattc acaagagaaa agcctgaatc
    10081 aagaggtacg gaattaagca acccttacaa aactgaaaaa accgatgtca aggatcaact
    10141 cattgcgaga tctgatgata atattgatct aatatccaca ccaagcagac gttgacaaaa
    10201 acgcttacat ctgctactat ggaagcatat ttatctaact aaaaaggagg ttctaccatg
    10261 aaacaagaat ggtttgaaag taatgatttt gtaaaaacaa caagcaagaa caagcctgaa
    10321 gagcaagctc aagaggttgc agacaaggct gaagaaacga tagccgattt cgatacacca
    10381 attgaaaaaa atactcagtt agaggaggaa gtctctcaag ctgaagtcga attggaaagc
    10441 cagcaagaag agaaaattga agctcctgaa gacagtgaag cgagaacagg aatagaagaa
    10501 aagaaggcat ctaattctac tgaagaagag ccagaccttt ctaaagaaac agaaaaagtc
    10561 actatagctg aagagagtca agaagctctt cctcagcaaa aagcaaccac gaaagagcca
    10621 cttcttatca gtaaatcttt agaaagtcct tatatccccg accaagctcc aaaatctagg
    10681 gataaatgga aagagcaagt gcttgatttt tggtcttggc tagtggaagc gatcaaatct
    10741 cctacaagta agttggaaac aagtatcaca cacagttaca cagcctttct cttgctcatt
    10801 ctgttttctg catcttcctt tttctttagt atctatcaca tcaaacatgc ttactatgga
    10861 catatagcaa gcattaacag tcgcttccct gagcagctag ctcctttaac tcttttttct
    10921 atcgtctcta tcctagtagc gacaacactc ttcttctttt cattcctctt gggtagtttc
    10981 gttgtgagac gatttatcca ccaggaaaag gactggacgc tagacaaggt tctccaacaa
    11041 tatagtcaac tcttggcaat tccaatcttc ctcactgcta ttgctagttt ctttgctttc
    11101 tttgatagcc tacgatttac agccctcttg tatgtgatta gcattggaat cattctgctt
    11161 gccagtctcc atatcattac aagaccaagt caagcaagtg aaaccgacgc cttctatcaa
    11221 ttattcttgt ctgtccttgt gaacggagtt attatcctcc tcttctttgt agctgaagtg
    11281 gcactgattg gagattatct tcgtatcttg gcctttcttt aaaattcaat cctgtcatcc
    11341 ttggcaggat tttttctatg tcaaaaaagc aagtcgatta acctgcttct gctttacttt
    11401 tcttgtgcta atgttttaaa atcttgtcct agggtgggtt gtatttctaa ttgattggcg
    11461 tctagctggt ggtaaaaaga tgggggtaac acctctaaga attttgcata gtccaagcga
    11521 gctatggatt catagtcttc tggtttagag ccgtctcctg tgatttgaac caagtcaatc
    11581 tcccactgga cttccttatc caccaattgc tcaatatagg ctgcaggaac aaacgattct
    11641 ctcggtaaaa ctgtcttgac tccttgagct agatggtaaa cgccatgcac ttttccttct
    11701 ccatcctgat agaaggaaac tctcgcaaag taggcatctg tctcttgaac cacacgcaca
    11761 cgcgcttcaa actgagccaa gccatctgcc tctaaaaagc ttttcaagtt ctcacgacta
    11821 aagaaaatag gattaaaaat tccttggcaa atcgtaaaac gagctacagg gtctgctaga
    11881 taggcttgaa tatttgcttg gaaataagct tcaaaatcaa aaccatctag cccttcaata
    11941 tcagtccctg tataagcaag caaagcatct aaaaatgact tgataatctg ccagtctgtc
    12001 tttgttagta ggtcaggaag atcgacacgg taagcctttt gaccatcagc ataactgacc
    12061 ttaaagagaa attgtgattg ccccactatc gcacactcga tatattcgag acgattaaga
    12121 ggctgacgga gatagactac atcatagcta tgtgactcca aaccgtctag caaggccaag
    12181 atcgacttgg cattcaaaat ctcttgttct cctaaaatgc tctgtttatt tggaataaaa
    12241 aatgttttcg ccataactgg actcctttga aatcgtttac atacagtata ccttattttt
    12301 ctgaaagata caaaaacaaa ctttatactc ttcgaaaatc tcttcaaacc gcgtcagttt
    12361 cgccttgccg tagatatatg taactgactt cgtcagtctt atctacaacc tcaaagcagt
    12421 gctttgagca gcctgcggct agcttcctag tttgctcttt gattttcatt gagtattaga
    12481 tttttgagta caaagcatag aaaaacagcc cctgaggact gtttgatctt atacagtagc
    12541 tgcttgatcc aagctttcac cgatagcggc taggcgctca atcacttcag cttgtgtcaa
    12601 ttcatttttt gaaacatagc ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg
    12661 aaggtacttg tcttcatttt cttctgatgt caagatacga cggttacaga agggatttcc
    12721 acagttgaca taacgttcac atggtgttcc atcaaaccag tctttcccta cgatggttgg
    12781 gttgacatgg ttgacatcaa cggcgatacg ctcgtcaaat acgtacattt ttccatccca
    12841 aagctcacct tgaacttctg ggtctttacc gtaagttgcg attcctccgt gcaattggcc
    12901 gacatctttg tagccttcac ggaccatcca gcctgagaat ttctcacagc gaacgccacc
    12961 tgtacagtaa accacgacac gcttgtccat gaatttttcc ttgttatcac ggacccattg
    13021 tggtaactca cggaagttgc gaatatctgg gcgaatagct ccacggaaat gtcctaggtc
    13081 gtactcataa tcgttacgtg tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt
    13141 gaactctttt ggagacaagt aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa
    13201 gtcgttgtct tccaaaccaa ggtggacaat ttctttcttg tagcgaacaa acatcttctt
    13261 gaaggcttgt tcattttctt cgtcaatctt gaaccagagt ccttccatac ctgggaggct
    13321 gtgaacgtag tccatgtatt tttgagttgt ttcatagtca cctgaaactg ttccgttaat
    13381 tccctcgtca gcgactagga tacggccttt aaggccgatt gatttacaga aagccaagtg
    13441 gtctgcagca aattgctctg cattttcaat tggagtataa aggtagtaaa gtaagacacg
    13501 aatatctttt gccataagat ttgttctctt ttctattctt aaattttcta aattttttat
    13561 ttatccatac tagtatacct gcttgagaaa acgaatgcaa tttatttgac tggaaattgt
    13621 agaggattct cgaaatttcc tgaatggtta aaataaggac aagagaaaac agggatatct
    13681 atatccttgt gccaaaaaaa ccactgccct ccccagacca acctgaggaa agcagtgatt
    13741 cttattttag gagttaggaa tgaatacacg aaatcaattt agctgattat tttttgtttt
    13801 tcaagaattc atcgtattgt ttttgcattt cgttcaatac tttttcgtag gcaccttcag
    13861 atttcaattt ttccatcaat tctggaatcg ctttatctgg gtctacagta ccagtgttga
    13921 tagctgtatc aaattgttgc attgtgttag caatagctga gatttcagat ttcacattgt
    13981 cagtattaaa gataaatcca agcgctggag attctttagc ttctgccaat tctttcttag
    14041 aattttcgat ttgttggtct gtaacgtttt cgttgatgta aaggatccag ttgttaccag
    14101 tgttccatcc acccatgtga gtgtttcctt tgtagccatc aagaacgcga acacggtttt
    14161 ctttaccttc aattttttcc cagttcttgc cttctggacc gtaaacaaga ccgttcaaga
    14221 gttctgggtt cgtattcaag aggttcaaga tttccattga tttttctttg ttcttagagt
    14281 tgtttgagat gacaaagtta gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa
    14341 ttggtttgat ttggatatct ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag
    14401 ctggtcctac tgtttcttca cgaacgaacc aagtatcttg ttgaaggtca aatgaagtat
    14461 cgcttgttgc gacatctttt ggaatgtagc cagcttcata gaatttgtga agagtcttca
    14521 agtgttcttt gaaacgaggc acttcgtaac ggtttacaac tttagtagta tcgccttcaa
    14581 ggtcaataac gaatggaaga ccgtttgcta ctgggtagtc aaagttatca gatgggatga
    14641 aaactttacc aatagcaaat ggtactacgt ctggagcttt ttctttaatt tgtttcaaga
    14701 ctggctcaag agtttcgtaa gaagtaacac ctgaaatatc gataccatat ttggcaagga
    14761 gagttccgtt gaaggcaaag ttttgagatg atgcaacgtt ggctgcaact ggtacagcgt
    14821 aaattttacc gtttacagta ttacccttga tgtaagctgg gtcaagtgcc ttgtaaaggt
    14881 ctttaccttc ttttttgtac aattctgtca agtcagcata agcacctttt tgagcattta
    14941 caatatagtt atctgcaaag gcgatatcat agttttcacc agatgatgtg ataactgaca
    15001 ttttcttacc atagtcaccc cagccaaggt attggatatc caatttggca ccaacttttt
    15061 cttcgatgat tttgttggca tttgctaaca attcatccaa gttatctggt ttgtcaccga
    15121 tttggtacat ttttataaca ggtttgtcac ctgaatcagc agcttttttg ctgttacctg
    15181 tcaaatttcc acaagcagca agacctgcag ccaaagcgac tacactagca gatgcaaaag
    15241 catatttttt ccagtttttc atgataaaaa ctcctttttt tatttttaaa cttataaaca
    15301 atgtaatgat cttatactca atgaaaatca aagagcaaac tagaaaacta gccgcaggct
    15361 gtacttgagt acggcaaggc gacgttgacg cggtttgaat ttgattttcg aagagtatta
    15421 acttcacaca agggaagttg ggaactgaga aatgttattt ctcaataagc actattcttt
    15481 cacaccaccg atagtcaaac cttttacaaa gtagcgttgg aagaatggat acaaaatcgc
    15541 gattggaagg gttgcaacca caaccatggc catacgacct gtttctttcg gtagagcaac
    15601 tcccagttga ccagtcaagc cgaccgcttt ggcaatgtag tccatatttt gttggatttg
    15661 catgagcaaa tattgcaatg gatacaagtt gtcactcttg atgtaaagaa gggcgttgaa
    15721 ccagtcattc cagaaaccaa gagctgttaa gagcgtgatg gttgcgatac ctggtagtga
    15781 caatggcaaa cagatttgga agaaaatccg ggcttcactg gcaccatcga tacgagccga
    15841 ttctagaatg gcttctggaa tggtcttctt gaagaaggaa cgcatcaaga tgatgttaaa
    15901 tggtgagaga agcattggaa caatcaaggc ccaaacagta tccccaagct gaagcacacg
    15961 ggtcaccatg atataacctg gtaccaaacc agcgttgaac aacatactga gaaggacgaa
    16021 gatggtaaaa aatctgcgat acttaaaggt tgtccgtgaa atagcgtagg cataggttgt
    16081 tgtgataaag acatttgtca atgtcccaac tacggttaca aagacagaga tgaagagggc
    16141 ttgtaggatt ttatccttaa actgtgccaa aaactcaaaa ccgtctaagc caaattggga
    16201 tgggaagaag ctatagccgt attggaggag gcttttctcg tctgtcactg aaataatgat
    16261 aacgaataca aaaggtagga tacaagagag ggcaatcaaa cccgaaatga tactgaagaa
    16321 gatatctgct ttcttactga aggagtgaat gccgacatta tcaatttttt cttttttaat
    16381 tttctttttt gccatattct cctcctttct agaacaaagc tgagtttgga tcgactcgtc
    16441 ttgcaagcaa gtttgatagg ataaccagaa tcaaaccaac aacggattgg taaagaccgg
    16501 ctgctgcagc cataccgata tctgctgtct gagtcaaacc attaaaaaca tatacgtcca
    16561 aaacgttggt tacattgtaa agctgaccag cattgtgtgg gatttgatag aagagaccga
    16621 agtctgcgcg gaagatattt ccgactgcaa ggatggtcaa tacagttaca agcggagtca
    16681 actgaggaat ggttacgttg cgaatacgtt gccacttgct agctccgtcc actgtcgctg
    16741 cttcgtagta ggttggatca attcccatga tcgtcgcata gtacatgaca ctgctatatc
    16801 caaaaccttt ccaaatacct aggaaaagta ggagataggg ccagatgccc aggtcagcgt
    16861 agaaattgac ttctttgaga ccaagacttt ccaatagatg attgaacacc cctttatcaa
    16921 tatttaggaa ggcatctgta aagaaactga tgataaccca agacaagaag taagggaaca
    16981 acatagaagt ttggaaaatc ttcaccattc tcttagaacg gagctcgctg aggataatgg
    17041 caatccctac agatacaact aaacctagaa agataaagcc aagattgtag aggacagtat
    17101 ttcgtgtgat aataaaggcg tctcttgaac taaataagaa tctgaaatta tcgagtccga
    17161 cccatttact atttatgata ctatctatga aaccattact ggtcatgtgg tagtctttga
    17221 aggcaaccac gttcccaaat actggaatgt aaaagaatag aatcaaccag agtgcccctg
    17281 gcaaaaccat caagagaaag atccagttgt ctctcaatgt ttttgaaaac tttttcataa
    17341 tttcctccct ttttattttg atatccatct aaaaattctt ttttagactt ttgataacga
    17401 ttacattatt agtatactcc tatttgcagg ttaggttaaa ctcctaatta tagaaaaaac
    17461 tccacaaatt atgtagcaga tttaaaactt tatcaccact atcaaacaaa tgtcctaaat
    17521 caattgttta ttttatctct attagcccag tgatggcgtc actctgttat aagcatccaa
    17581 caacggggta tactgaaaaa tctccagact agggaactca gcgatagttc ctaatctgga
    17641 gatttttaat atgttattag gcgtttgctt tcaacttagc aataacctct ttaagattat
    17701 caatcaactc tgcttcagta tgctcagagc ctttttcatc tgccaagaac aaaactgctt
    17761 tttgaagttc ttcttgagag ttttcaagga catccttatc tgctgtttct ttgcccgctg
    17821 tttgtcctcc atccttagtt gctgactggc tttccttaat ggactctagg gaagcaatgg
    17881 catctttgac tgtttgcaag atatcacgta aaccttgctc tgtcaaacta tcatctgtaa
    17941 gagctttctt agcctctgcc aaaaccagac gtgctgaatc tgtggtagga ttcgatacac
    18001 ctgtcaatga tctcaaaaga ttttctaaag tttgagtctg cttactaata ctagactaaa
    18061 atcaaaaagc attacataac agtgatatga aatcaactaa agaagaaatc caaaccatca
    18121 aaacactttt aaaagactct cgt
//
LOCUS       DAVHSH010000038        17900 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000038 DAVHSH010000000
VERSION     DAVHSH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.038"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            312..2291
                     /locus_tag="VVR08_001438"
     CDS             312..2291
                     /locus_tag="VVR08_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6075344.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            2358..3854
                     /locus_tag="VVR08_001439"
     CDS             2358..3854
                     /locus_tag="VVR08_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075345.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRIYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPLTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            3854..4780
                     /locus_tag="VVR08_001440"
     CDS             3854..4780
                     /locus_tag="VVR08_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075346.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            4789..5856
                     /locus_tag="VVR08_001441"
     CDS             4789..5856
                     /locus_tag="VVR08_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075347.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            5867..6793
                     /locus_tag="VVR08_001442"
     CDS             5867..6793
                     /locus_tag="VVR08_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075348.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(6868..8194)
                     /locus_tag="VVR08_001443"
                     /pseudo
     CDS             complement(6868..8194)
                     /locus_tag="VVR08_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(8320..8553)
                     /locus_tag="VVR08_001444"
     CDS             complement(8320..8553)
                     /locus_tag="VVR08_001444"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075349.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(8546..8662)
                     /locus_tag="VVR08_001445"
     CDS             complement(8546..8662)
                     /locus_tag="VVR08_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6075350.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(8877..9227)
                     /locus_tag="VVR08_001446"
     CDS             complement(8877..9227)
                     /locus_tag="VVR08_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6075351.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            9483..12116
                     /gene="polA"
                     /locus_tag="VVR08_001447"
     CDS             9483..12116
                     /gene="polA"
                     /locus_tag="VVR08_001447"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU6075352.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            12201..12638
                     /locus_tag="VVR08_001448"
     CDS             12201..12638
                     /locus_tag="VVR08_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU6075353.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(12821..13831)
                     /locus_tag="VVR08_001449"
     CDS             complement(12821..13831)
                     /locus_tag="VVR08_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU6075354.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            13980..15149
                     /locus_tag="VVR08_001450"
     CDS             13980..15149
                     /locus_tag="VVR08_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6075355.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFASAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            15146..15916
                     /gene="recO"
                     /locus_tag="VVR08_001451"
     CDS             15146..15916
                     /gene="recO"
                     /locus_tag="VVR08_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU6075356.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            15913..16905
                     /gene="plsX"
                     /locus_tag="VVR08_001452"
     CDS             15913..16905
                     /gene="plsX"
                     /locus_tag="VVR08_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU6075357.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVGIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTIDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            16911..17144
                     /locus_tag="VVR08_001453"
     CDS             16911..17144
                     /locus_tag="VVR08_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6075358.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            17190..17481
                     /locus_tag="VVR08_001454"
                     /pseudo
     CDS             17190..17481
                     /locus_tag="VVR08_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            17684..>17900
                     /gene="blpU"
                     /locus_tag="VVR08_001455"
     CDS             17684..>17900
                     /gene="blpU"
                     /locus_tag="VVR08_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6075359.1"
                     /translation="MNTKKMSQFEIMDTDMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAA"
BASE COUNT         5217 a         3290 c         4100 g         5293 t
ORIGIN      
        1 aactgaatct tgaatactag aatgatactt ctacaatatt gttataattt aatttgaatt
       61 ccaaaatcac attgttccgt ccgtatttca ttttactgta tgtcttccta aactccaaag
      121 tttctgcgtc aaatttccta ttttcactgt agtctttgac acttcgaacg acaatttgaa
      181 tcatatattc aaaaaaaaat gaaaaatttg tgccaacaag cctaaatatt ctgaaaattt
      241 gtttgatttt taatggataa tgtgatataa tggttgtcaa tctataattc acataaacag
      301 aggagtagaa aatgaaaaaa aatcgtgtat ttgctacagc aggtcttgtt ttattagcag
      361 caggtgtact tgcagcatgc agttcttcaa aatcatctga ttcatcagcc cctaaagctt
      421 atggctatgt ttatacagca gacccagaaa ccttggacta cctgatttca agtaaaaata
      481 gtacaacagt agtgacttca aatgggattg atggtttatt cactaacgat aattacggta
      541 atcttgctcc tgcagttgca gaggattggg aagtctctaa ggatggtttg acctacactt
      601 ataagattcg taaaggggtt aaatggttta cctctgatgg agaagaatat gcagaggtga
      661 cggctaaaga ttttgtgaac ggtttaaaac acgcagcaga taaaaaatca gaagctatgt
      721 atttagctga aaattcggtt aaaggcttgg cagattatct atcaggaact tcaacagatt
      781 tttcaacagt tggtgtcaag gcggttgatg attatacgtt acaatacact ttgaaccagc
      841 ctgaaccgtt ctggaactct aagttgacct attctatttt ctggcctctg aatgaagaat
      901 tcgaaacatc aaaaggaagc gattttgcta aaccaacaga tccgacatcc ttgctttata
      961 atggtccatt cttgttgaaa gggttgactg caaaatcttc tgtagagttt gtaaaaaatg
     1021 agcaatattg ggataaagaa aatgtccacc tagatactat caatctagct tactatgatg
     1081 gatcagatca ggagtcgcta gagcgtaact ttactagtgg agcttatagt tatgcccgtc
     1141 tttaccctac cagctccaac tattctaagg ttgcagaaga atacaaggac aatatctatt
     1201 acacacaatc aggctctggg attgctggtc tgggtgtgaa tattgatcgc caaagttaca
     1261 actatacttc taaaactaca gattcagaga aagtagctac taagaaggca ttgcttaaca
     1321 aagatttccg tcaagccttg aattttgctc ttgatcgctc agcttactca gctcaaatca
     1381 atggtaaaga tggagcagct ttagcagttc gtaatttatt tgtaaaacca gactttgttt
     1441 cagctggtga gaagaccttt ggtgatttag tcgctgctca acttcctgct tatggtgatg
     1501 agtggaaagg tgtgaattta gctgatgggc aggatggttt attcaatgct gacaaggcca
     1561 aggcagagtt tgcgaaagct aagaaagctt tagaagcaga cggcgttcag tttcctattc
     1621 atctggacgt tccagtagac caagcatcaa aaaactacat atctcgtatt cagtccttta
     1681 aacaatctgt agaaacagtt cttggtgttg aaaatgtcgt tgttgatatt caacaaatga
     1741 caagtgatga attccttaat attacttact atgctgccaa tgcttcatct gaggattggg
     1801 atgtatcggg aggagtttca tgggggccag actatcaaga cccatctact tacctggata
     1861 ttttaaaaac aactagcagt gaaactacaa aaacatattt aggatttgat aatccaaata
     1921 gcccttcagt agttcaagtt ggtttgaaag aatacgataa attagttgat gaagctgcca
     1981 aagagacaag cgacttgaat gtccgttatg aaaaatatgc agcggctcaa gcatggttga
     2041 cagatagttc actctttatt cctgctatgg cttcttctgg tgcagcacca gtgctttcac
     2101 gaattgttcc atttactgga gcttctgcgc aaacaggctc taaggggtca gatgtttact
     2161 tcaaatattt gaaattacaa gataaagtgg tgactaagga agagtatgaa aaagctcgtg
     2221 aaaaatggtt gaaagaaaaa gctgaatcaa atgagaaagc tcaaaaagaa ttggcaagtc
     2281 atgtgaagta aataatttct aatagaactt tctctccatg aggagaaggt tcttttggga
     2341 tttttaaagg aaataatatg aaaaaatata tttttatgcg tgttttgcgg tcattggttt
     2401 cgattttctt agtaacgact ttgacctaca cgattatcta taccttggtt cctcgaaaat
     2461 tgattttcaa gcaggatcct aactataata aaattgcgac aacggctgat aaacgtgata
     2521 actatgaaaa tactgtgttt gagcgtatgg gctacattga gtattacgat actaaagagt
     2581 tgcaagaaaa ggcaagtagc atggattctt ctgtaacagt agaagcaaat gcgaccaata
     2641 aagctattta tgaaaagtac atcaatcaat taggtcatgg ttggactttg ggagaattta
     2701 ctgaaagtgg tcaattctat gctactcgtg aaattccaat ttttgaacgt gtttttcact
     2761 tctatgctaa cttgattgac attgaccata caaataaaat ccaagaccct gaaaatccag
     2821 acttgaaacg ctaccttcgt tttgaaaatg atccagctat cggatggtca ttggtcggtt
     2881 caggaactaa acataaatat ctcttgtact ttaacagtca gttcccattt gttcatcaaa
     2941 actttgtgaa cttgaattta ggtgactctt acccaaccta tgctaataca ccagttcttc
     3001 aggttattac tcaaggtcaa ggacaaacca aaactgccca agttcagttc ccaacaggta
     3061 agaaaacgtc ttctgtaaat atttactcaa gaatctacaa gtcacctagt caggctgact
     3121 ctcgtgaagt agctagctat gggaaagatg atccttatac agcgactgaa agtaattacc
     3181 aatatccatc tatgattgtc agctctgcta ttactggttt gattggtttg gttcttgcct
     3241 atgctcttgc cgtgccactt ggttcagcca tggctcgttt caagaacact tggattgata
     3301 gcctctcaac agggactttg accttcttgc ttgctcttcc aacgattgcc ttggtttaca
     3361 tcgttcgatt gattggatca tctattgccc ttccagattc attccctatc ttgggagctg
     3421 gagattggcg ttcttacgtt ttaccagcag tcatccttgg tttgttgggt gctcctctta
     3481 cagccatttg gattcgtcgt tacatgattg acttgcaatc tcaagacttt gttcgtttcg
     3541 ctcgtgcaaa aggtttgtct gaaaaagaaa tttcaaacaa acacatcttt aaaaatgcca
     3601 tggttccgct ggtttcagga attcctggtg ccattattgg ggttatcggt ggtgcaaccc
     3661 ttactgaaac agtcttcgcc ttcccaggta tgggtaaaat gttgattgac tctgtaaaag
     3721 catctaataa ctctatggtc gttggtcttg tcttcatctt tacatgtatt tctatcttct
     3781 cacgtctttt gggagatatt tggatgacta ttattgaccc acgtattaaa ttgactgaga
     3841 aaggaggcaa ataatgtcta caatcgataa agaaaaattt cagtttgtaa aacgtgacga
     3901 ttttgcctct gaaactattg atgcgccagc atattcttac tggaaatcag tgtttaaaca
     3961 atttatgaag aaaaaatcaa ctgtagtcat gttgggaatc ttggtagcca tcattttgat
     4021 aagtttcatc tacccaatgt tttctaagtt tgatttcaat gatgtcagca aggtaaatga
     4081 ctttagtgtt cgttatatca agccaaatgc ggagcattgg ttcggtactg acagtaacgg
     4141 taaatcgctc tttgacggtg tctggttcgg agctcgtaac tccatcctca tttctgtgat
     4201 tgcgacagtg attaacttgg ttatcggtgt ttttgtcggt ggtatttggg gtatttcaaa
     4261 atcagttgac cgtgtcatga tggaagttta caacgtcatc tcaaacatcc cacctctttt
     4321 gattgttatt gtcttgactt actcaatcgg agctggattc tggaatctga tttttgccat
     4381 gagcgtaaca acatggattg gtattgcctt catgatccgt gtgcaaatct tgcgctatcg
     4441 tgacttggaa tacaacttgg cgtcacgtac tttgggaaca ccaaccttga agattgttgc
     4501 caaaaatatc atgcctcaat tggtatctgt tattgtgaca accatgactc aaatgcttcc
     4561 aagctttatc tcatacgaag ccttcttgtc tttcttcggt cttggattac cgattacagt
     4621 gccaagtttg ggtcgtttga tttcggatta ttcacaaaac gtaacaacca atgcttactt
     4681 gttctggatt ccattgacaa cccttgtctt ggtatccttg tcccttttcg tagttggtca
     4741 aaacttagcg gatgctagtg atccacgtac acatagatag gagtagaaat gacaaaagaa
     4801 aaaaatgtaa ttttgactgc tcgcgatatt gtcgtggaat ttgacgttcg tgataaagta
     4861 ttgacagcca ttcgcggcgt ttcccttgaa ctagtcgaag gagaagtatt agccttggta
     4921 ggtgagtcag gatcaggtaa atctgttttg acaaagacct tcacaggtat gctcgaagaa
     4981 aatggtcgca ttgcccaagg tagtattgac taccgtggtc aggacttgac agctttatct
     5041 tctcacaagg attgggaaca aattcgtggt gctaagattg cgactatctt ccaggaccca
     5101 atgactagtt tggaccccat taaaacaatt ggtagtcaga ttacagaagt tattgtaaaa
     5161 caccaaggaa aaacagctaa agaagcgaaa gaattggcca ttgactacat gaataaggtt
     5221 ggcattccag acgcagatag acgttttaat gaatacccat tccaatattc tggaggaatg
     5281 cgtcaacgta tcgttattgc tattgccctt gcctgccgac ctgatgtctt gatctgtgat
     5341 gagccaacaa ctgccttgga tgtaactatt caagctcaga ttattgattt gctaaaatct
     5401 ttacaaaacg agtatcattt cacaacaatc tttattaccc acgaccttgg tgtggtggca
     5461 agtattgcgg ataaggtagc ggttatgtat gcaggagaaa tcgttgagta tggaacggtt
     5521 gaggaagtct tctatgaccc tcgccatcca tatacatgga gtctcttgtc tagcttgcct
     5581 cagcttgctg atgataaagg ggatctttac tcaatcccag gaacacctcc gtcactttat
     5641 actgacctga aaggggatgc ttttgccttg cgttctgact acgcaatgca gattgacttc
     5701 gaacaaaaag ctcctcaatt ctcagtatca gagacacatt gggctaaaac ttggcttctt
     5761 catgaggatg ctccaaaagt agaaaaacca gctgtgattg caaatctcca tgataagatc
     5821 cgtgaaaaaa tgggatttgc ccatctggct gactaggagg aaggaaatgt ctgaaaaatt
     5881 agtagaaatc aaagatttag aaatttcctt cggtgaagga agtaagaagt ttgtcgcggt
     5941 taaaaatgct aacttcttta tcaacaaggg agaaactttc tcgcttgtag gtgagtccgg
     6001 tagtgggaaa acaactattg gtcgtgctat catcggtcta aatgatacaa gtaatggaga
     6061 tatcattttt gatggtcaaa agattaatgg taagaaatcg cgtgaacaag ctgcggaatt
     6121 gattcgtcga atccagatga ttttccaaga ccctgccgca agtttgaatg aacgtgcgac
     6181 tgttgattat attatttctg aaggtcttta caatcaccgt ttatttaagg atgaagaaga
     6241 acgtaaagag aaagttcaaa atattatccg tgaagtaggt cttcttgctg agcacttgac
     6301 tcgttaccct catgaattct caggcggtca acgtcaacgt atcggtattg cccgtgcctt
     6361 ggtcatgcaa ccagactttg ttattgcaga tgagccaatt tcagccttgg acgtttctgt
     6421 acgtgcccaa gtcttgaact tgctcaaaaa attccaaaaa gagctcggcc tgacctatct
     6481 cttcatcgcc catgacttgt cggttgttcg ctttatttca gatcgtatcg cagttattta
     6541 caagggtgtt attgtagagg ttgcagaaac agaagaattg ttcaacaatc caattcaccc
     6601 atatactcaa gccttgcttt cagcggtacc aatcccagat ccaatcttgg aacgtaagaa
     6661 ggtcttgaag gtttacgatc caagtcaaca cgactatgag actgataagc catctatggt
     6721 agaaatccgt ccaggtcact atgtttgggc gaaccaagcc gaattggcac gttatcaaaa
     6781 aggactaaac tagtaatggt tttataattt ccatgtcaat ttttatggaa attaggctct
     6841 ttgtcaactg tagtgggttg aagtcagcta agctcgagaa aggacaaatt tcgtcctttc
     6901 ttttttgatg ttcagggcga taaaaatccg ttttttgaag ttttcaaagt ttcgaaaacc
     6961 aaaggcattg cgcttgataa gtttgatgag attattggtc gcttccagtt tggcgttgga
     7021 ataaggtaat tgaagggcgt tgacgatttt ctctttatct ttgaggaagg ttttaaagac
     7081 agtctgaaaa agaggatgaa cctgctttag attgtcctca atgaatccga aaaatttctc
     7141 cggttcctta ttctgaaagt gaaacagcaa gagttgatag agctgatagt gatgtttcaa
     7201 gtcttccgaa taactcaaaa gcttgtttaa aatctcttta ttggttaagt gcatacgaaa
     7261 agtaggacga taaaatcgct tatcactcag tttacggcta tcctgttgaa tgagtttcca
     7321 gtagcgcttg atagccttgt attcatggga ttttcgatga aactgattca taatttggac
     7381 acgcacacga ctcatagcac ggctaagatg ttgtacaatg tgaaagcgtt caagaacgat
     7441 tttagcattc gggagtgaaa cagtctggga gactgtttca gcctgagcct agaaatttga
     7501 aagcgaagct gtttagccaa gtcatagtaa gggctaaaca tatccatagt aatgattttg
     7561 acgcgacatc ggacggctct atcatattta agaaaatgct ctcggatgac agcttgtgtt
     7621 ctaccctcaa gaacagtgat gatattgagc ttttcaaaat cttgcgcaat gaagctcatc
     7681 tccatctccc gattgaaaca gtcactcccc ggactgtttc aacgtcccaa gacataatct
     7741 taggcagatt tctaaaatta cactcaaagt ggaagtcatt gagctttcga atgacagttg
     7801 aagttgagat ggaaagctga tgggcaatat cggtcataga aatcttttca attaactttt
     7861 gagcaatctt ttggttgatg atacgaggga tttgatgatt cttcttgacg atagaagttt
     7921 cagcaaccat cattttagaa cagtgatagc acttgaatca acgctttcta aggagaattc
     7981 tagtaggcat accagtcgtt tcaagataag gaattttaga aggtttttga aagtcatatt
     8041 tcttcaattg gtttccgcac tcagggcaag atggggcgtc gtagtccagt ttggcgatga
     8101 tttccttgtg tgtatcctta ttgatgatgt ttaaaatctg gacattaggg tctttaatgt
     8161 ctagtaattt tgtgataaaa tgtaattgtt ccatatgatt ctttctaatg agttgttttg
     8221 tcgcttttca ttataggtca tatgggactt ttttttacac aaaataggct ccataatatc
     8281 catagtgggt aaatccccta tggatattat ggagccattt tacaacagtg cctcaaattc
     8341 agatactgac atacctaatt gctggctggc aacctcagaa gtcagaagac cttggcgtac
     8401 tatgtctagg aaggcaaaaa gtttcctttc tgcccttcct tcaactttcc cacgctctag
     8461 tccttgttca aggccttcag ccctagcagt ttccaaggca tagtcctgtg ctaacaagac
     8521 ttgttcttct cgcatatgta gttgactaaa cattttcctg tcctcctcgg accagctctt
     8581 gtagtccagc agttgatttg cttgggtaat ggctcgttgc ggttgctggg taaagggctt
     8641 gttgtcgaaa aactccaacc atggcttgcg aaccttgtct ttgctggttt ctctgtattt
     8701 tttaattcca agaatgccat cttaaccaga tggttttcct gtccattgtt ggtaatcgcc
     8761 aatacctcac ctgttgtgtc ttcgcgcata ctaaagctat gaaaagccag gtcatctgag
     8821 aaataattac tatccacgat agcaatgacg taaacaggag cgatgtgttt gtagatctag
     8881 tgagtatcac cttctcgctg acgaattttt tcaagatttt gattaacctg actgcacagg
     8941 taagcccaca agtgattgat gaaaaaattc tgatgatgga cttgaatctc aataattact
     9001 tgagtaccgt tatccaactc cgccaagacg tctatactgg tataaaaatc ctgcaccgag
     9061 taaggcatgg agagtaatac gtgaatatcg cttccctcca aaatggtcac attttttgct
     9121 ggcaagtcca gcatatcgcg aataaattga caagtgattt ctggattgct gaatattttc
     9181 ttagcaatca aatcattagt tgggctgatg cccggatgtc tgagaatcct cctattcctc
     9241 cttctatagt gagttgaaat aagatgtgaa taactctatc aggaaagtca aattaattta
     9301 tagaaatatt ttagcagtca aggtgtacta ttatagattc aatatactat attatagcac
     9361 atttttaaat ctaggtttac taaattctct ggctctatct atttattcgg aaaaagtttg
     9421 aaaaatactt gctctagctc ttcccaatgg tattttttga ttctttcctt tataatgggt
     9481 gtatggataa gaaaaaatta ttattgattg atgggtcttc tgtagctttt cgggcgtttt
     9541 ttgcgctgta tcagcagttg gaccgtttta agaatgcggc tggtttgcat accaatgcga
     9601 tttatggttt tcagttgatg ttgagtcatt tgttggagcg ggttgagccg agtcatattt
     9661 tggtggcttt tgatgcggga aagacgacct tccggacaga gatgtatgcg gactataagg
     9721 gtggtcgggc caagactcct gatgaatttc gtgagcaatt tcctttcatt cgtgagttgc
     9781 tggatcatat ggggattcgt cactatgagc tggctcagta tgaggcggat gacatcattg
     9841 ggacgctgga taagctagca gagcaggatg gttttgatat taccattgtc agtggggaca
     9901 aggatttgat tcagctgacg gatgagcata cggtggttga aatttccaag aaaggtgtgg
     9961 ctgagtttga ggcctttacg ccagattacc tcatggaaga aatgggcctc acaccagctc
    10021 agtttatcga tctcaaggcg ctcatgggtg ataagtcgga taatatccct ggggtgacca
    10081 aagtcggtga aaagacgggt attaagctct tgctggagta tggttcgctt gaggggattt
    10141 atgaaaatat tgatggaatg aagacttcta agatgaagga aaatctcatc aatgacaagg
    10201 aacaggcctt tttgtctaaa acactagcga ccattgatac caaggcaccg attgcgattg
    10261 gtttagagga cttggtctat agtggtccag atgttgaaaa tcttgggaaa ttttacgatg
    10321 agatgggatt caaacagctc aagcaggctt taaatgtgtc gtcagctgat gtgtctgaga
    10381 gtttggattt tactattgtt gaccaaatca gtcaagatat gctgagtgaa gagtctatct
    10441 tccactttga gctttttggt gagaattacc atacggataa tttggttgga tttgcctggt
    10501 cttgtgggga taagctctat gccacagaca agcttgagct gttgcaagac ccgattttca
    10561 aggatttctt agaaaaaaca tctctgagag tttatgactt taagaaggtt aaagttcttt
    10621 tgcaacgttt tggtgtggat ttgcaggcgc ctgcttttga catccgtttg gctaaatacc
    10681 tcctttcgac tgtggaggac aatgaaattg cgaccatcgc tagtctttat ggtcagactt
    10741 acttggttga tgatgaaact ttctacggta agggtgttaa aaaggccatt cctgaacgtg
    10801 agaaattctt ggaacactta gcttgtaaac ttgctgtttt ggtagaaaca gagcctattt
    10861 tacttgaaaa actcagcgaa aatgggcaat tagagcttct ttatgatatg gagcaacctc
    10921 tggcttttgt ccttgccaag atggaaattg ctgggattat ggtcaagaaa gagaccttgc
    10981 ttgagatgca ggctgaaaat gagcttgtca ttgaaaaact gactcaagag atttacgagc
    11041 tggctggtga ggagtttaat gtcaactcgc ctaagcagtt gggcgtgctt ctctttgaga
    11101 aattgggact tcctctagaa tacactaaga aaaccaagac aggttattcg acagcagtgg
    11161 atgttttgga gcgtctcgct cctattgctc cgattgttaa gaaaatcctg gattaccgtc
    11221 aaattgctaa gattcaatct acttatgtaa ttggcttgca ggactggatt ttggctgatg
    11281 gaaagattca tactcgctat gtgcaggatt tgacccagac cgggcgtttg tctagtgtgg
    11341 atccaaactt gcaaaatatt cctgcccgat tggaacaggg gcgcttgatt cggaaggctt
    11401 ttgtgccaga gtgggaggat agtgtgctac tcagctctga ctattcacag attgaattgc
    11461 gcgttttggc gcatatttct aaggatgagc acttgattaa ggccttccaa gagggggcag
    11521 atatccatac ttcgacagcc atgcgggtct ttggcattga gcgtcctgat gatgtgactg
    11581 caaacgaccg tcgcaatgcc aaggcagtta actttggagt ggtttatggg atttcagact
    11641 ttggcttgtc taataatttg ggaattagtc gtaaggaagc caaagcctac attgatacct
    11701 actttgaacg ttttccaggt attaaaaact acatggatga agtggtgcgg gaggcgcgtg
    11761 ataagggcta tgtagagacc ctctttaagc gtcgccgtga gttgccagat atcaattcgc
    11821 gcaacttcaa tattcgtggt tttgcggaac gaactgctat caactcacct atccagggtt
    11881 cggcagcaga tattctcaag attgccatga ttcagctgga taaagccttg gttgcaggtg
    11941 gttatcagac taagatgctg ttacaagtgc acgatgaaat cgtccttgaa gtgcctaaat
    12001 ctgaattggt agagatgaaa aaattggtga aacaaaccat ggaagaagcc attcaactca
    12061 gtgttcctct tatcgcagat gagaatgaag gggcaacctg gtacgaggct aaataaaaag
    12121 ggggctagtc ctcctttttt gtagtataat tctgcaaacc ttttcaaaat gtgctatact
    12181 gatgaaaaag gaggatttct atgagtcaag aatttatcaa tccaagtgat ggcgtgattc
    12241 gtcagtatct cgcaacgagt aaaacccttg ctgtggtggg tttgtctgac cgtgaagaaa
    12301 caaccagcaa tcgagtaaca aaggaaatgc aggctcgggg ctataaaatc atcccagtca
    12361 atcccaaggc ggcaggtggc gaaatcttgg gtgaaaaggc ttatgctagc ctcgctgaaa
    12421 ttccttttcc tgtagatatt gtcaatgttt atcgtcgcag tgaatttctg cccgatgtgg
    12481 cgcgtgattt tctcaaagct gatgccaaga ttttttgggc acagctagga cttgaaagtt
    12541 tagaagcgaa agagattttg cgtgatggtg gatgtgatga tatcgtgatg aatcgctgta
    12601 tcaagagaga acatactcgc ttgattgagg aagcataaga aaaaggtagc tgatgggcta
    12661 ccttttgtgt tatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcgggctgc
    12721 tcaaaacacc gttttgaggt tgcagataga actgacgaag tcagtaacat atatacggca
    12781 aggcgacgtt gacgtggttt gaagagattt tcgaagagtg ttagaaaatg ccgataaggg
    12841 tctgcatacc aagagtggtg aggatgatgg caatccagca gatggctcca agaagaatgg
    12901 attttccact ggatttgacc atagcgacca gattggtttt gagaccgata gcactcatgg
    12961 ccatgacaat aaggaattta gagagttctt tgagaggagt aaagaaacta ctggacacac
    13021 ctagagaggt gagtagtgta gtgaggagag aggcaaggat aaagtaaagg ataaaaagtg
    13081 ggaagacttt tttcagttgc aggctttgct tgttttcttg ttggcgactt tgccagtagg
    13141 atagaaagag cgtgataggg ataatggcca aagtacgtgt gagtttaaca atggttgcag
    13201 actcgagggt attgctttgg taaagactgt cccaagcgct ggcggcagcc gttacagagg
    13261 aagtgtcgtt gaccgcagtt cctgcaaaga gggcgaagcc gtcattggat agatgaagcc
    13321 aggtgccgag ggttggaaag atgagcgcag ccaagacatt gaagaaaaag ataacggaga
    13381 tggcttgggc tacttccttt tccttagcat ggataacagg cgctgtcgct gcaatggcag
    13441 aacccccaca gatagaagaa cctactccaa tcaaggtagc cagttttgta tccagggcaa
    13501 agaagcgctg gaagaggtag gcaacaatca aggctattga aatggtggaa aggatgacag
    13561 ggagtgaaga ttggccaact gcgaagactt gagagatatt gagaccaaaa ccaagtaaga
    13621 taacggcata ctggagcaat ttcttggaac taaaggtcaa tccagcatcc agttgtttat
    13681 aagacgagag aaagggatgt aggagcatgc ccataaaaat cgcaaaaacg ggtgcgccaa
    13741 tcacagggaa gaatcctcct aagtaccaag ataggatgga aatgagaagg cagaccaaga
    13801 tgcctgctcc attttttgat agaaatgaca taaaaacctc caaatagaat ctgttaccat
    13861 tatagacctg taaagaggaa aagtaaaata gaaagtggaa agctattctc taatgtattt
    13921 ttgcggtcgg ggggcttttg tagtataata gagatacgtt ttgaaagtag gaggtatcta
    13981 tggacttaac taagcgcttt aataaacagt tagataaaat tcaagtttcg ttgattcgtc
    14041 agtttgacca ggctatttcg gagattcctg gggtcttgcg tttgaccttg ggggaacctg
    14101 attttacaac gccagaccat gtcaaggagg cggccaagcg agcgattgat cagaaccaat
    14161 cctactatac agggatgagt ggtctgctga ctctacgtca ggcagctagt gactttgtta
    14221 aggaaaagta ccaactggac tatgctcctg aaaatgaaat cttggttaca attggggcga
    14281 cagaggcttt atctgcgact ttgacggcta ttttggaaga gggagacaag gtacttttgc
    14341 cagctcctgc ttatccaggc tatgaaccga ttgttaactt agttggggca gaaattgttg
    14401 agattgatac gactgaaaat ggttttgtct tgactcctga gatgttggag aaggccattt
    14461 tggagcaggg tgataagctc aaggcggtta ttctcaacta tccagccaat ccgacaggaa
    14521 ttacctacag tcgagagcag ttagaggcct tggcagctgt tttacgcaag tacgaaattt
    14581 ttgttgtctg tgatgaggtt tactcagaat tgacctacac aggcgaagcc catgtgtctc
    14641 taggaacgat gttgagagac caggctatta ttatcaatgg tttgtctaaa tcgcatgcca
    14701 tgacaggttg gcgtttgggg ctgattttcg cttctgcggc cttcacagcc cagttaatca
    14761 agagtcacca atacttggtc actgccgcaa ataccatggc gcaacatgct gcggtagaag
    14821 ccttgacggc tggtaaaaat gatgcggagc ccatgaagaa ggaatatatc cagcgtcggg
    14881 actatatcat cgaaaaaatg actgctcttg gttttgagat tatcaaacca gacggtgcct
    14941 tctatatttt tgctaaaatt ccagcgggct acaatcaaga ctcctttgct tttctgaagg
    15001 attttgctca gaagaaggcc gttgccttta tccctggtgc agcctttgga cgttacgggg
    15061 aaggctacgt ccgcctatct tatgcagcca gcatggagac tatcaaagaa gccatgaaac
    15121 gacttgagga gtacatgaga gaagcatgat tcagtctatc acgagtcaag gcttggtgct
    15181 ttacaatcgc aattttcgtg aggatgataa gctcgtcaaa atttttacag agcaggttgg
    15241 caaacgcatg ttttttgtca aacacgctgg tcagtctaag ctggcgcctg ttattcagcc
    15301 cttggtgctg gcacgatttc tcttgcgaat caatgatgac ggactcagtt acatcgaaga
    15361 ctatcatgag gtcatgactt ttcccaagat taatagtgac ctctttgtca tggcctatgc
    15421 gacctatgtg gcagctcttg cagatgctag tttgcaggac aatcagcagg atgctccctt
    15481 gtttgctttt ttgcaaaaga ctttggagtt gatggaagca ggcttggatt atcaggtttt
    15541 gaccaatatt tttgaaattc aaattttgac tcgatttgga atcagcctca attttaatga
    15601 gtgtgtcttc tgccatcggg ttggtcaggc ttttgacttt tctttcaaat atggagcctg
    15661 cctctgtcca gagcattatc atgaggatga gagacgttgc catctcaatc ccaatatccc
    15721 ctatctgctc aatcaatttc aagctattga ttttgagact ttggagacca tttcgctcaa
    15781 gcctggaatc aagcaagagc tacgccaatt tatggatcaa ctatatgaag agtacgttgg
    15841 gattcaccta aaatcaaaga aatttattga ttccctagca gactggggac aattactaaa
    15901 agaggaaaag aaatgaaaaa aatcgcagta gatgccatgg ggggcgatta cgcacctcag
    15961 gccatcgttg agggtgtcaa tcaagcccta tctgactttt cagatatcga ggttcaactc
    16021 tacggagatg aagctaaaat caagcaatat ctgacagcga cagagcgcgt cggcattatc
    16081 catacggatg agaagattga ttcggatgat gaacctacga gagctattcg gaataagaaa
    16141 aatgccagta tggtattggc agccaaggct gtcaaagatg gtgaagcaga cgctgtcctt
    16201 tcggctggga atacaggtgc tttgttggct gctggattct tcatcgtggg tcgtatcaag
    16261 aatatcgacc gtcctggact tatgtcaaca ttgccgacta tagatgggaa aggttttgac
    16321 atgcttgacc tcggtgctaa tgcagaaaat acagcccagc acctccatca atacgctgtc
    16381 ctaggttctt tctatgccaa gaatgttcgt ggcattgcgc aaccacgtgt tggtttgctc
    16441 aacaacggaa cagagagtag caagggcgac ccgcttcgta aggaaactta tgaattactg
    16501 gcggctgatg aaagtttgaa ctttatcgga aacgtggaag cgcgtgattt gatgaatggc
    16561 gttgcagatg ttgttgtggc agatggtttc acgggaaacg ctgtgctcaa atccatcgaa
    16621 gggacagcta tgggaatcat gggcttgctc aagacagcta ttacaggtgg tggtcttcga
    16681 gcgaaactag gtgccctcct tctcaaggac agcctcagag gtttgaaaaa acagctcaat
    16741 tattcagatg ttggtggagc ggtcttgttt ggtgtcaagg cacctgttgt caagactcat
    16801 ggctcaagcg atgccaaggc tgtttatagt acgattcgcc agattcgtac catgctagaa
    16861 acagaagtag ttgcccagac tgcgcgtgaa ttttcaggag aataaaagag atgaaagaaa
    16921 aagaaatttt tgacagtatt gtgaccatta tccaagagcg acagggagag gactttgtcg
    16981 tgacagaatc cttgagtctg aaagacgact tggatgctga ctcagttgat ttgatggagt
    17041 ttatcttgac gctggaggat gaatttagta tcgaaatcag cgatgaggaa attgaccaac
    17101 tccaaagtgt aggagatgtg gttaaaatca ttcaaggaaa atagcaatcg gagttccaag
    17161 tcaacggaag tagatggttt ttagaaatga gaaatatcgg acaagctggt aaaatcttgg
    17221 ctgacagtgg ttatcaaggg ctcatgaaga tatatcctca agcacaaact tccacgtaaa
    17281 tccagcaaac tcaagccgct aacagttgaa gataaagcct gtaatcatgc gctatctaag
    17341 gagagaagca aggttgagaa tatctttgcc aaagtaaaaa cgtttaaaat gatttcaaca
    17401 acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc
    17461 aatcatgaac taggattcta gttttgcagg aagtctaata gtaaaaaagt gattagaaaa
    17521 catctttttt aaaaatagag atgattttga aacaaaaaag ctaattcaag acgtttcgat
    17581 gccaattcaa gatttggatg aaaaaaatta atagatactg ttatactaaa cttgtcaagt
    17641 ttgtaacaag acaaatatta aaaataaaaa agaggtattc gttatgaata caaaaaagat
    17701 gtcacaattt gaaattatgg atactgatat gcttgcttgc gttgaaggtg gcggatgcaa
    17761 ttggggagat tttgccaaag caggtgttgg aggaggagca gcacgaggtc ttcagctagg
    17821 aattaaaaca agaacatggc aaggtgcagc aactggtgct gtgggaggag ctatacttgg
    17881 aggtgtggcc tatgcagcga
//
LOCUS       DAVHSH010000039        17765 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000039 DAVHSH010000000
VERSION     DAVHSH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.039"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(159..644)
                     /locus_tag="VVR08_001456"
                     /pseudo
     CDS             complement(159..644)
                     /locus_tag="VVR08_001456"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(677..1015)
                     /locus_tag="VVR08_001457"
     CDS             complement(677..1015)
                     /locus_tag="VVR08_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075360.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            complement(1028..1801)
                     /locus_tag="VVR08_001458"
     CDS             complement(1028..1801)
                     /locus_tag="VVR08_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6075361.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2247..3002)
                     /locus_tag="VVR08_001459"
                     /pseudo
     CDS             complement(2247..3002)
                     /locus_tag="VVR08_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(3140..4762)
                     /gene="groL"
                     /locus_tag="VVR08_001460"
     CDS             complement(3140..4762)
                     /gene="groL"
                     /locus_tag="VVR08_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU6075362.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4778..5062)
                     /gene="groES"
                     /locus_tag="VVR08_001461"
     CDS             complement(4778..5062)
                     /gene="groES"
                     /locus_tag="VVR08_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU6075363.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5332..5727)
                     /locus_tag="VVR08_001462"
     CDS             complement(5332..5727)
                     /locus_tag="VVR08_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6075364.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5805..6566)
                     /locus_tag="VVR08_001463"
     CDS             complement(5805..6566)
                     /locus_tag="VVR08_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6075365.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6599..7225)
                     /locus_tag="VVR08_001464"
     CDS             complement(6599..7225)
                     /locus_tag="VVR08_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU6075366.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7241..7558)
                     /locus_tag="VVR08_001465"
     CDS             complement(7241..7558)
                     /locus_tag="VVR08_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU6075367.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(7555..7854)
                     /locus_tag="VVR08_001466"
     CDS             complement(7555..7854)
                     /locus_tag="VVR08_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU6075368.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(8139..8330)
                     /locus_tag="VVR08_001467"
     CDS             complement(8139..8330)
                     /locus_tag="VVR08_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU6075369.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(8491..9165)
                     /locus_tag="VVR08_001468"
     CDS             complement(8491..9165)
                     /locus_tag="VVR08_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075370.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIHGDVAFGKL
                     EIVYAK"
     gene            complement(9171..9617)
                     /locus_tag="VVR08_001469"
     CDS             complement(9171..9617)
                     /locus_tag="VVR08_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075371.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9731..10234)
                     /locus_tag="VVR08_001470"
     CDS             complement(9731..10234)
                     /locus_tag="VVR08_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6075372.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(10231..10593)
                     /locus_tag="VVR08_001471"
     CDS             complement(10231..10593)
                     /locus_tag="VVR08_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU6075373.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10659..12518)
                     /locus_tag="VVR08_001472"
                     /pseudo
     CDS             complement(10659..12518)
                     /locus_tag="VVR08_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(12557..13006)
                     /locus_tag="VVR08_001473"
                     /pseudo
     CDS             complement(12557..13006)
                     /locus_tag="VVR08_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(13130..13846)
                     /locus_tag="VVR08_001474"
     CDS             complement(13130..13846)
                     /locus_tag="VVR08_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6075374.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14727..16142)
                     /gene="ply"
                     /locus_tag="VVR08_001475"
     CDS             complement(14727..16142)
                     /gene="ply"
                     /locus_tag="VVR08_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU6075375.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(16153..16485)
                     /locus_tag="VVR08_001476"
     CDS             complement(16153..16485)
                     /locus_tag="VVR08_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075376.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16556..17164)
                     /locus_tag="VVR08_001477"
     CDS             complement(16556..17164)
                     /locus_tag="VVR08_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075377.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17177..17635)
                     /locus_tag="VVR08_001478"
     CDS             complement(17177..17635)
                     /locus_tag="VVR08_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU6075378.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
BASE COUNT         5263 a         3973 c         3069 g         5460 t
ORIGIN      
        1 acaacaaact tatatcgttt aatacaaaaa atacgaaaat gattagtata aaaaatacag
       61 gtcaacttcg tatcaaaaac atttttttgt atttccacat agcatcaatc atttagtaca
      121 atattttaaa aacaatatct taacagagaa aatgatattt aatctatcag ctcatttaat
      181 cgtttttgaa aatataaagc aatactttta gattcaataa actcaaaata ttttatgaca
      241 ttgtccattt gtttaattcc agattcttta gattctgtca ggtatatttt atatccttct
      301 acaaatttga atgtagattt ttcaaaaact tttgtgtcat cttttaataa tttttgtaat
      361 ttcatttcaa agtagtctgc atatattaga tgtgaatttt caaggcaaca gaaccaaaaa
      421 tttaaacaag ctgacacaac taaatttcta ttcttgccga ttttttcgta ataatgtgta
      481 cgctctagta tttcttttcc gaccatgtaa atataatcta tttcaaaaag atgatataaa
      541 ttaccaatca gcgttatctc ataggactcc catcgttcct tctggaataa atagtcatat
      601 actaaattta gatcatctct actaactaca tgattacaat ctagctgatt tcataatccc
      661 tgaaccataa ttgtatttat tttatgagtt ttttcccact cttctcaaaa agtttttgtt
      721 gcttattttt tattacctcc aatcctttaa tattcaaact ataaaaattt ggagataaat
      781 taaccaaaaa atcatcacgc tccgatcttt tataatattc taagtgatta caaaaattct
      841 ctatcgaaac attgatattt gataataatt caaaaaatgt tgaaagagaa atttcatttt
      901 ctcccctttc aaatctagaa agttgagatt ttgatataaa atcagctgca gcatactcta
      961 aagaatatcc gtttaatttt ctaaaatatc gaaaagcttc tccgtaattt ttcacacttt
     1021 cattccctta actttctttt cgagcgataa acataccata ttctttagga atgatcaaca
     1081 taccattatt aaactcactt tccaatcttt tacgtattat ttcctcttct agtgaaccta
     1141 tttctgaaat tcctttaaac gattggatgt atttaactag gtcatctata ctagttacct
     1201 gtaactcatc atcatagagt aatgtatcga cagagttaaa atacctactc aggtaccttt
     1261 taccattttg taaagtaaac gttctatttt ctaaatcttg attaacctca tctttaaata
     1321 aacttgccaa ataatttaca actccatttt caccaaatgt agcacagtaa aaaatgcctc
     1381 cggtttttaa gaccctattc acctcagaga gagctttagg aatatcattc acatgatgta
     1441 gaagcatatt agcaataaca atatcaaaag tttcattctc aaaagaaatc ttttgaatat
     1501 ccattatctc ataattgaca ttgtttctat ttccaatcac tgacttcgtt gattttacca
     1561 tatctttaga aaaatctgta acaatcaact gcttcatttt atctatagaa tcactattac
     1621 ttttccacaa ttctcctgta ccacatccca attctagaac ctttacttca tcagtgattt
     1681 ggtagttaga aaatatccaa ttattaaatc ccaatttatt ttttgaatac ttcttatgca
     1741 attctactcg aatatcaaga ttatcatgac ttttatattg ttcaattact ttatcaatca
     1801 ttttaaatga cctccactct ataatttggc attatatcac aagaataaag atagtgttaa
     1861 ataagttata taaatgcaaa aaaggaatat tccgttatag cagagttgta acacatttct
     1921 ataaagaaat ttattcctac gactcagttt ggcatgctta acttcctaac tcaaaaacaa
     1981 agcatcgatt aatttatccg ttcttctttt gaaacagatt tgaactgata attgctcgtt
     2041 ttaatttaaa aagctctttt gagcaaaact tcattttttt aagagtccaa caatttctgt
     2101 ctatcgcttt tctactagca aaaaacctac cttgaggcaa gttttcattt atatatctaa
     2161 tttcgtaaca gtatagtaaa atgaaataag gacagtcaaa tcgatttcta acaatgtttt
     2221 agaagtaaag gtgtactatt ctagtttcaa tctactataa atttgatatg agaatagtct
     2281 ttctcaacat ccttatccaa caagcatgct gtggcgtcct tcttaactta aaccaggtca
     2341 atattctggg cttgggctgc atagacgcag ccacaataac attgacgata gatatcatac
     2401 tcctcacaca tctctactga acgtttgtag ccttgatttt tcttgaaatc gttgggaaga
     2461 tagtggggcg tgtaaatttt ttgcacatcg attccgatgc tattgatagt ttgagaattc
     2521 ttatgaggac tgatggtcaa ggctgaacca aagtagtcaa agcccaagtc catagccact
     2581 tgcgctgttt tatccagtcg gtagtcaaaa caaaccttgc aacggtcgcc accttcgggc
     2641 tcctcctcta gccccctaac tagttttcgg tattaattgg gttcgtaggg agcttctagg
     2701 tactgaaccg tatttcctgt ccgctcatta aaatcactaa caaatttctt ggtgacatag
     2761 acccgcttat ggtattctgc cttgggatgg atattagaat tggcaaaata gatggtcaca
     2821 tctgcatact tggtcaaata ttctagtgta taggtactac aaggggcaca gcaaacatgc
     2881 acgagaatgg ttggccgcta ctcatttttt tcccatgctt gtaccatttt ctgcatgaca
     2941 cggtcataat taatcttctg attgggggtc atcttgcaca gaatttcttc tacatcgatc
     3001 atgttcttct cctttttcta gtcttatttt atcatataag ttaggagagc tcaaatcaat
     3061 ttagaagtga atattataaa aagaagggtt agtcattccc tccttttgtg ttttttataa
     3121 gttgttttct atagaaagct tacatcatcc cgcccatcat acttggatcc attgctggag
     3181 ctggggctac tggttctggt ttattggcta cgactgcttc tgttgtcaaa atcaagctgg
     3241 ctacagatgc tgcattttgt agggctgaac gactcacttt aactggatca atgatacctt
     3301 gatcaatcat gttaacccac tcgccagttg ctgcgttgaa tcctatacca agctcagcat
     3361 ttttcaaacg atcgataacg atagatcctt caaatcctgc attgtgagca atttgacgaa
     3421 caggttcttc caaagcacgg agaacaatat tacgtcctgt tgcttcatct cctgtcaatt
     3481 ccaaggtagc aacagctgga atcacattgg caagagctgt tccaccacct gcaacaatac
     3541 cttcttcaac agctgcacga gtagcgttga gggcatcttc aatgcggagt ttcatttctt
     3601 tcaactcagt ttcagttgcg gctccgacct taataaccgc tacaccacct gacaatttgg
     3661 ccaagcgttc ttgcaatttt tcacggtcaa attcagaagt tgtagtttcg atttgagact
     3721 tgataaccgc aacacggtga gaaatcgctt caggatttcc tgcaccttct acaataaccg
     3781 tgctatcttt gtccacggtc actctcgctg cttgaccaag agcttcaatt gtcgcatctt
     3841 tcaactcaag accaaggtct tctgtgataa ctgttccgcc tgttaagatg gcgatatctt
     3901 caagcatggc tttgcgacgg tcaccaaaac caggtgcctt gactgctact acgttgaagg
     3961 ttccacgaat cttgttcaaa acaagagttg gaagagcctc gccatccaca tcatccgcaa
     4021 taatcaagag tggacgattg ctttggagaa tgctttccaa aagtggcaag atttcttgga
     4081 tattggaaat tttcttgtct gtaatcaaaa tgtacggatt ttcaaggtca gccaccattt
     4141 tttcgctatc agtcaccatg tactgtgaaa ggtaaccacg gtcaaactgc attccttcta
     4201 cgacttcaag ctctgtttcc ataccacgtg actcttcgat ggtgatgaca ccgtctttgc
     4261 caactttttc cattgcttca gagatgtact caccaacttt ttcagaacga gaagatacgg
     4321 ctgcaacttg agcgatagct tctttattgg caacagggat ggcgttgttt ttcaaagctt
     4381 caactgctgc ggcaactgct gtttcaatcc cacgacgaat accgattgga tttgcacctg
     4441 ctgtgacatt tttgattcct tcacggacga tagcttgggt caagactgtt gcagtcgtag
     4501 tcccgtcacc tgcgatatca ttggttttag aagctacttc tgatactaac ttagcaccca
     4561 tattttcaaa atggtcttcc aattcgattt ctttggcaat ggtcacaccg tcattggtaa
     4621 tcaagggtga accgaatgac ttttcaagaa cgacattgcg accttttggt cccaaggtta
     4681 ctttaacagt gtctgcaaga atatcgacac cacgaaccat ggctgaacgg gcatctgatg
     4741 aaaatttaat ttcttttgac atacttactt tctccttcta ttcctcaatg attgccaaaa
     4801 tgttagcttc gcctacgata atgtactttt catcgccatc tttgacatca agacctgcgt
     4861 gggcttcaac taagacacga tctccagttt taacacttgg agcaaccaag tcaccgttca
     4921 aggtacgaac accttgtcca gtagccacaa cttgagctgt tttggttttt tcttgggctg
     4981 agcctgcaag gacaaagccc ccaacggttt gttctttttc ttctattttt aagaccacac
     5041 ggtcccctaa tggtttcaac atctgatttc ctccataatg agatagatat tattagcact
     5101 ctttgaactg gagtgctaat tcataattct attgtatcac ttggtcagaa atagtcaaga
     5161 aaaaagtctg actttctcaa gataaaaagc ctgagaccaa ctcagacttt ttaatgttta
     5221 tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgctc aaagcattgc
     5281 tttgatgttg tggataaagc taacgtggtt tgaagagatt ttcgaagagt attaaaatgg
     5341 caattcttcc tcttccaaga ctaaatctgc caaatcttgg cctgcattat tttcacgcat
     5401 ggcacgttga gcacgacttt ccaagagttg gaatcctgtt acaagtactt cggtcacgta
     5461 gttcatttgg ccatttttct caaagcgacg ggtacgcaat tctccatcaa cggaaatgag
     5521 actacctttg gttgcgtagc ttgccaaagt ttctgctagt ctgccccata ggaccatatt
     5581 gacaaaatca gcttcacgtt caccgttttg gtctttgtaa cgacggttga cagcgatagt
     5641 tgctcgcgct accgacttgt cattgttggt tttgtgcaat tctggtgtag acgttaaacg
     5701 cccaatcatg ataactttat tatacatatt ttcttcctcc tacttatcta ttcgtaggaa
     5761 atcaaaaaaa gttacagaaa tttgtaactt ttcgaggaaa tttcttattt tttatgaatc
     5821 atgaaacctg tcgcctgttg attggccata atggtcatat ctgtaatctg aacacggcga
     5881 ggctgactgg tcacatagac tactgtgtct gcaatatcct gagcttgcaa ggcttctatt
     5941 ccttggtaaa cggacgcagc tcgctcttta tcaccatgaa aacgaacagt tgagaaatct
     6001 gtttcgacaa tcccaggctg aatggttgtc accttgatat ccgttgcgat ggtatcaatt
     6061 cgcagtccat ccgaaaaggt cttaaccgca gccttggtag ctgagtaaac agcggcacca
     6121 gcataggcgt agattcctgc ggttgacccc atattgataa tatgaccttg attgactttt
     6181 atcattgctg gcaagaaaca gcgagtaacc gccatcagac ctttaacatt ggtatccaac
     6241 atggtcaaca tatccaactc ctcatagtct tgatagggag ccaagtcaag agccagtccg
     6301 gcgttgttga ccaagatatc aatcctccct atcgtttcta gaatatcaga gcaaacagtc
     6361 ttcaccatga ccatatccgt cacatctagt ggaaaagtcc agacggtttg atttggaaag
     6421 cttactgcaa actccgactt gaggatttct aatctgtcta tccgtcgtcc tgttagaacg
     6481 acatcctcac cctgctccag ataagcacgc gcaatcgctt caccgattcc tgaggttgct
     6541 cccgtaatca ctacattttt tgccatctta tttccttcta tcagatgctg acaagttcct
     6601 aggcagtcca gtgtttcgct gggtcgaacg gtgttccgac aacttggtct tctgataatt
     6661 caagcacccc acgtttttgc ggagcatttg gcaaatgcaa ttcacgagga ctacacatca
     6721 tcccaaaact cttttcacca cgaagttcgc ctgggaaaat gaaattccct tttggcatca
     6781 tggcaccagg aagagccaca atggttttca acccaacacg cgcattaggt gctcctgcaa
     6841 cgatttgcac tatcttgtca cttgcgactg caacttggca gatgttgagg tggtcactgt
     6901 ctggatgagc taccatctcg acaatttcac caacaacaaa cttaggttcc ttatcattaa
     6961 caatttcttc tgtaaaacct tccgcctgta attcttggtt caaacgagcg acttgctcat
     7021 ctgataaaaa gacttgaccg cgctctgcaa tttcaaacaa gctcgaaacc tcaaaaatgt
     7081 tccaagctac tgtttcccca ttatctttga gaaaaacacg ggctaccttg cctttgcgtt
     7141 ccacattcag tttggcatct ccgctatttt tcacgatgac cataaggaca tcaccgacat
     7201 gttctttgtt atacgtaaaa atcattgttt cctttttctc ctatttcaat cctgctaaaa
     7261 aatcgttaat ttgctcctta cttttacggt cgcgattgac aaaacgaccg atttccttgt
     7321 ccttttctag aacaacaagg ctaggaattc cgtaaacatc ccagagtttg gccaaatcca
     7381 tatactgatc tcggtccatt cgaataaagg tgaactctgg attggtctct tcaatctctg
     7441 gtaaggcagg ataaatataa cgacaatcgc cacaccagtc tgccacaaaa aggaagacct
     7501 tcttgcccgc tttttccact aaagatgcta attcttctaa acttgctggc tgtatcataa
     7561 gacttcctcc tcatagacta ggtcttcatt ttcatagaca aaggtataat gacggccatc
     7621 ctcaaaaatg acgccaccaa ccaagctctc cagactgctt tcgtaaactt gaacataaag
     7681 ggtcgcaatt tcccccatgt cggaaaaatg gtctcgcaca atctctgtca actcttcctg
     7741 agtcttcatg agcttacggt catctgcaac ttttttcgta gcaagagcaa ggcttccgat
     7801 acctagcaga gccagacctg ccatccacat ttttttagct ttcataccat tcattttaac
     7861 acaaaaaagg cttcaggaca aatgaggaag cagcagaaaa gcaagtaaaa agcctcttcc
     7921 tttaaggaaa aggacttctt atactaagag caaactagaa agctagccgc aggctgctca
     7981 aaacacggtt ttgaggttgt agataaggcg acgctgacgt ggtttgaaga gattttcaaa
     8041 gagtattatt cttattgcca ggcacctaag ttgccaacgt agtaaccatc aggtgtgtag
     8101 gtattgcgaa gcatcttacc tgatgaagcc agataatact acttgccatt gtctttgacc
     8161 caatcattcg caatcatgga accagaagaa cttacataat accattctcc cttgtcataa
     8221 acccaagtac tgactttcat ggttcctgag caattaaagg caaaaaaact gtccaatatc
     8281 attcgttttt taaaagcatt tgacactaca tcatctacgc tgtagtacat agatacatca
     8341 aacgtaaaag ccaaaatatc gaaaaatata caacttttaa aggcagcatt tcatttttta
     8401 aagtctaaca accatagaac tgaaatcaga gcaaggcatc aatttcctac tcttagtacg
     8461 cctattttga tggttgaagt gaagattttt ttatttagcg tagacaattt ccaacttccc
     8521 aaaagccaca tctccatgga taatcaaggt tttgctggtt ggggctacag gagcgtcagc
     8581 cttagctgca ccaaaggagg tttctacttt caaatctaca cgccagtgtt gtggaacata
     8641 gacggttgca ttcccgaagg ccacttcaat atttaaagtt gcaaaatcac ctagcatctc
     8701 tgcattatca tagtagattt tagcatcccc aaaagcgact tccacttggt catctacgag
     8761 atcttgatct tgcttataga aggtcccgct accaaaagcg acttccttat ccgtgacgac
     8821 tgtttttttc ccattgtacc accatttttt ttcattccag aacttacttg aatgcgtcag
     8881 ataaccaaca ccaagtacca ccaagatgct agcccaaata agagaatgat tggtaactgg
     8941 taacaagtca taagcgtaat ttgcaatgat gagcgccagt aaacctgtaa aaactgccga
     9001 agtgagatga cgtctaagga tggactcaat ggacttataa gcaaaaaaaa caatacctag
     9061 taaaggccat attttaccat ccaaagaagg aattccaaaa ttcccttgca gcaagatcca
     9121 agctgctaaa accaataaaa caataccaaa tgctttcttt ttcatgtttt ttacctcatg
     9181 tttcttagat tttcttttag gagggattgg taatgccgtg agacatgaac ctccttgtgc
     9241 gtctgataaa aggaaatggt gcccgttcct gaaaaggact tgtccactga gtaaatctga
     9301 cggatgtttg cgatcgttga cttggaaact cgattaaaat agcgaggcaa gatagactcc
     9361 aactcataga gcttgaggcg aacctcataa gcttccttct ggttatgagc gtagatcttg
     9421 ctcccttctg tttcaaagaa gagaatttct gacaggtcta gataatattc acctgtcccc
     9481 ttgtaaaaag tcaacctcgg agcctttgac tcttgcaaga gccgttgcaa gtctgcaatt
     9541 tcatctgtca aagtgggggt cttgatgaca atttcagtct cctctaaatt gccgtcaatc
     9601 tcaattcgta acttcatcac atctcctttc tgactctact atatcaaagc taagttagga
     9661 atacaagggc aaaaaagcaa gtggtcaatt tgaagcagta agtggttgta ggactagctt
     9721 aacttacatg tcagaatagg aagaaaagga atccccacac caaaccacaa gcatagccaa
     9781 ccaagacatc cttgggataa tgaacacccc ctaaaaccct caccaacccc agcaaagctg
     9841 aaaagatcaa gcatactaag ccaataggta gactagcatg cagacaggcc atggagatga
     9901 tagttgccga aaagacatgg cgactgggca tcgaccgtcc cgaactatcc ttatcaagaa
     9961 ggggacagat atcccaagtt tcataaggtc tcgggtgatt gattttctta cgaaacaggg
    10021 acaaggccac aaaacctgat gcaggaataa gcacataaac cccaacttgc tgaccaagtc
    10081 ctagttgcag gtaagtggtg actagcaaga tcagatagac caggggcatg gcgactgtca
    10141 tcaaacgatt gaaactgcgt aataggaata aaagaattgg acgactagtt agtctggatc
    10201 tgatatttcg ataccattct tgataatttt tcatttatgc ttctcatact tttctagaac
    10261 ttgttgagat gttttcccct tggcaagcca atccactagc ttgtccaagc gacgtatttc
    10321 ctgcatcaga ggatcatcaa tttcctcaat acggacaccg caaatcttcc ctgtaattgc
    10381 aattcgttca gggacataat atggtgcttg tcgaaaaaaa tctccgtaag taacatccct
    10441 atccagacaa gcaagaacgt cactcacttc ataccctgtc aaccaactgg tcacttggtg
    10501 aactgactct gcctttccac cctttcgctc aacttttgca atcaaggcta agtagacagc
    10561 agcaaatttc atattgtata atttctgact catacttctc tctttctatg tgtactagta
    10621 taaataagaa aaagaaggcc gtcaagcctt cttttgattt attcttctgc ttcatcttct
    10681 gtaaattgac tattgtacaa gtcagcgtag aagccacctt gcgccatcag ttcctcatag
    10741 ttgccttgct cgatgatatt tccatctttc atgaccaaga tcaagtctgc atttcggatg
    10801 gttgacaagc ggtgggcaat gacaaaggat gtgcgtcctt ccatcaaacg gtccatggct
    10861 ttttggatca attcctctgt ccgtgtgtca acagaagaag tcgcctcatc caaaatcaaa
    10921 agcggtgcat ccttaagaag ggcacgagca atagtcaata gttgtttttg tcctacagac
    10981 aaggtcacgg tgtcatccaa gatggtatca tagccatctg gcaaggtcat aataaagtgg
    11041 tgaattccca cagccttact agcttccatc attcgttcat cactaatccc tatttgatta
    11101 tagatgagat tgtctcgaat agttccttca aagagccagg tatcctgcaa gaccattgaa
    11161 aaggcatcat gcacttctga acgcgtcata gccttggtat ccacaccatc aatgtgaata
    11221 cttcccttat caatctcata gaatttcatc aaaagattga caatggttgt cttaccagtc
    11281 ccagtcggcc caacaatggc aaccttttga ccagcatgag ctgtcgcaga gaagtcatag
    11341 tcttgaacat tgacaccgtc caccagaatt tctcctgctg acacgtcgta gaaacgtgga
    11401 atcagattga ccagagttga tttaccagaa cctgttgacc caataaaggc cactgtttga
    11461 ccagtttctg ctttaaagct aacatgttca ataactgcct ccgaatttgc cgcatagcgg
    11521 aaggtcacat ccttaaactc gacctgacct ttgaagtttt catcagtcag ctgcacttga
    11581 acagggtttt ggatagaaga atgcaaatct aaaacttgat taatccgctt agcagagacc
    11641 atagttcggg gaagaacgat gaagagtgct cccatgagaa ggaagcccat gacaacctac
    11701 atggcataag acatgaaaac aatcatgtca ctaaagagag gcagacgcgc tatcggagca
    11761 gcgtcgttaa tcacataggc cccaatccag taaatcgcta cactcaaacc acttgaaatc
    11821 cccatcatga taggattcaa aatagccata agacggttga caaacaaatt caaacgggtc
    11881 aattcatcat ttactgctgc aaatttttca ttttgataat cctctgcatt gtaggcacga
    11941 acgacacgaa tacctgttaa actctcacga gtgatactgt tcagtttatc tgtcaacccc
    12001 tgaatcaagg actgttttgg aaaggctagc gtcatcaaaa cggtcgtcat caggacgttg
    12061 acaatcacta ccacaagtac ggcccagagt cagtattctg aatgacctaa aatcttccca
    12121 atagcccaga tagccataat tggaccacgc gttaccactt gcaagcccat agtaatcaac
    12181 atttgaactt gagtaatgtc attggtagta cgcgtcaaga ggctaagaat tgaaaatttc
    12241 ttaatctctg tctgcgagta atccaaaact cggttaaaaa tatcacttct cagcctacta
    12301 gtataagaag ccgccactcg ggatgcaaaa aatccaactg caactacgga caagaaggca
    12361 agaaagagca ttcccatcat catgcttgcc ggctgccaca actcatctaa attagtttct
    12421 tgactaccta gcaaatccgt aattttcgag atataggtcg gcacttccaa ctctagatag
    12481 accgaaaagc aagtaaagag aatggctagt aaaatcatcc cccattcttt tctactaatt
    12541 cttttggtta atttctttat tctctcctcc tattcccttg atattttgcc tgtagttgac
    12601 cgagaacttt ctcaaaaatc agtaattcat cttcatcaat gtcttccatc aactgcttgt
    12661 ctatgcgttc aaaaaaagcc ttaacctgtt gcatctgaga acgtgctttg tccgtcagac
    12721 gaacaaactt agcccgctta tcaacaggac tcgcctccaa ttccaccaaa ccattttgca
    12781 ctatacgctt aaccagatta ctagcaacag acttggtaat attgagttcc tgctcgatat
    12841 ctttaatcaa gaccaagtct tggtttttct agcgattatc caaaaaacgc acaacctgac
    12901 cttgcggccc acccataaat tcaatgccgc aacgtttggc ttccttttgc accatcaggt
    12961 aaatttgatg accaaaacgc ttaaagacta acatcggttt atccataatc tcccccttct
    13021 aaataaaaat agttctctgg agaataatta aatttctatg agaactattt tcttgattaa
    13081 aaaaatccca agtgattttc tcacttagga tcatgttcta taggttaaat taaaacccat
    13141 ctacgttcgt ataaatcttt tggacgtctt cgtcgtcttc aagaacgctg taaagttttt
    13201 caaaggtttc aaggtcttcg cctgacaatt ccacttctga ctgaggaatc atttccaatt
    13261 cagtcacttg gaattcttca ataccagact cacggagagc aacgatagcc ttgtgaaggt
    13321 cagttggcgc tgtgtaaact gtgattgtac cttcttgtgc ttctacgtca tccacatcca
    13381 catccgcttc gagcaattgc tcaaagactg cgtccgcatc ttcacctcca aatacaataa
    13441 cacctttgtt gtcaaaaagg taagaaacag aacctgaagc gcccatgttt ccgccgtttt
    13501 taccaaaggc tgcacggaca ttggctgctg tacggttaac gttagaagtc aaagtatcca
    13561 caattagcat agagccattt ggcccaaaac cttcgtaacg tccttctgta aaggtttcgt
    13621 ctgtgtttcc tttggcttta tcaatcgctt tatcgataat gtgttttggc acttgggctt
    13681 gtttagcacg gtcgataacg aatttcaaag ctgagtttga ttctggatct ggatcacctt
    13741 ttttagctgc tacatagatt tctacaccaa attttgcata tactttagag ttagctccat
    13801 ctttagccgt tttcttggct acgatattgg cccatttacg tcccattagg aatctccttt
    13861 tttcacattt taatctttct tattataaca caagtttttt tgattttcac tagaggaaat
    13921 ggattttatt agcaaatcaa gctaggatag cactttacct gctaagatgg tcttgccttt
    13981 ctatctttat caacagacac tcatccacat tcaaaaaaca aactagacca ttatctgcaa
    14041 atagaaagtt tcagccaagt ttgacaaagt cagctcaaat tactgtttga agtttgtaga
    14101 tataagcgac aaaaacaatc atactgcacc ttttgttgac agtctactcc agacatatca
    14161 tagttcaagt aaatactttg aaattcaaca gttcttatag gcgctattgt attctaagaa
    14221 atcaatagaa gagtttctaa gcaaacctct aatactcaat aaaaatcaaa gagcaaacta
    14281 gaaagctagc ctcaggttgc tcaaaacact gttttgaggt tgcggatggg gctgacatgg
    14341 tttgaagaga ttttcgaaga gtataattta cgtgttccca agatggagaa gttagactag
    14401 tacactggca cttctaaaac attgctagca attgatttgt tcatatttaa tttcattttt
    14461 tccataaatg ggtattagat ataaacagca aaatatttcc gatacgtgtc gttcttgaat
    14521 ttccaatcat ctaaaacaag taaaggataa tcaatcccct gtatatcaag gaattggcta
    14581 ccctttttac ttttttacac attctgtttg atagattcat tttaacatca cgagcatact
    14641 ccaatggaaa tcgctaggca agagataaac tttcagatat ccgcagagag atcatcgcct
    14701 ctttttgtcg caagcattct cctctcctag tcattttcta ccttatcttc tacctgagga
    14761 tagagagttg ttccccaaat agaaatcgtc cgcttacgca ctagtggcaa atcggttttt
    14821 tcataaaccg tacgccacca ttcccaggca agcccggtac actctctaat tttgacagag
    14881 agattacgaa cattcccttt taaaggaata ctagtggtaa agtgagccgt taaatcctgc
    14941 ccatttctgt cccaagcctt aggagtcaag acttccttac cttgatgatc ataggataat
    15001 tcattccaag taatataata ttgggcaaca taggcaccac tatgatccag cagtaaatct
    15061 ccgtttctgt aagctgtaac cttagtctca acatagtctg tactattttg aaaggtcgca
    15121 actacattgt cacgtaaaaa agaagttgta taggaaatcg gcaagcctgg atgatctgct
    15181 gtaaagcgac tgccttcttg aatcaagtcc tctaccatat ccaccttgcc tgttacaact
    15241 cgggcacccg aacttgggtc gccccctaaa ataaccgcct tcacttctgt attgtccaaa
    15301 atctgtttcc actctgtctg aggagctacc ttgactcctt ttatcaaagc ttcaaaagca
    15361 gcctctactt catcactctt actcgtggtt tccaacttga gatagacttg gcgcccataa
    15421 gcaacactcg aaatatagac caaaggacgc tctgcagaaa ttcctctctg ttttaaatcc
    15481 tctaccgtta cagtatcttg aaacacatct cctggatttt taacagcatc tacgctgact
    15541 gtataataaa tctgcttaaa attaacaatc tgaatctgct tttcgcctga atggacagag
    15601 ttaaaatcaa tatcaagaga attccctgtc ttttcaaagt cagaaccaaa cttgaccttg
    15661 agttgttcca tgctgtgagc cgtgattttt tcatactgca ttctagctgg gacattattg
    15721 acctgaccat aatcttgatg ccacttagcc aacaaatcgt ttaccgctcc gcgaacactt
    15781 gaattgctgg ggtcttccac ttggagaaag ctatcgctac ttgccaaacc aggcaaatca
    15841 atactataag tcatcggagc acgatcgacc gcaagaagag tgggattatt ctctaacaag
    15901 gtctcatcca ctacgagaag tgctccagga tagaggcgac tgtcgttggt agctgttaca
    15961 gaaatatcac ttgtatttgt cgacaagctc cgcttctttc tttcgataac aacaaactca
    16021 tcgggtagct gattaccctc tttgatgaaa cgattttcaa tactttctcc ctgatgggtc
    16081 aagagtttct ttttatcgta attcatagct agtataaagt catttactgc tttatttgcc
    16141 atcttctacc tcctaataag ttcctggatt gagttgcata aactcagact tgttcagcga
    16201 aatcagccgt ggttggacta agtaatccaa aatttcctcg tacaattctt ctgagacatt
    16261 gcgtcgccgt ctggctaaat aagaagtcgg aatgaccgta ttatccaaca taaatacctt
    16321 atctaagtca atcaaggttg gtcttgtaaa aggattacga gctagatccg gctcttctat
    16381 cataaagttc ttgaccaaac gtctggtcaa gagagctggt ttgaaggtct gatttttaac
    16441 caactctttg tttttagtca tgctgttgtc aatacagata tacatatgat tcttcacagc
    16501 caaatcgcta ctaatagtcg gaaaaggcaa ataaagagct acaacatctc ctctcttaat
    16561 caagcaagag cacccccttt tctcctaatg taacatagac aggattgacc aagtcttctg
    16621 attgactcag aatttccaaa gtttgagttt ggcgcgctgt caatttagta gcatcttgtc
    16681 tcttcaatac aaaatgcttg tcgccaataa ccttgacaat ataatccttc tccaaagctg
    16741 actggtaaat ccacatcaga tgttgtctgt cctgagaact caagagagaa ggattttcaa
    16801 gcctcccgat agtctgataa aaatcaaaaa caggagctaa ctcctgccaa tctgattggc
    16861 tagttgtcaa ggctagaaaa agggctttgc gagctgatac ttcttggtta gccttgagag
    16921 ttactttccc ctccaagttt tttagaaatc gggaaactcc agaaagcaaa tttttctcta
    16981 actgcgagaa ataaaaacct ttcgttccca gacataagtc tttcatgtcg ctttctctag
    17041 caaataagag ctcaaacatt tgatagtaaa agaaaaatat ctggcactgg gtcgcgctca
    17101 tcttttcctt atcggcttct ttttttaacc agagcaaggg cgacaggtag ctggattgag
    17161 acatttcctc tacctcctac tcttttttaa ctggagcatc tgcactagct gccacttctt
    17221 ttgactggat actttcccac tggttaatct cctctgagat aagaccttcg catgtcttga
    17281 caaatagggc aaaagccttg gtctttcctg catatttctc cgtttggcat tgatagagga
    17341 atttttcttt ctccaggagt tgcgcagttt tttggtaaga aatccaattt tcctttgcat
    17401 tatacaaatt gataatcccc tcacacagca agccgagact ggataaggca accgaaatca
    17461 aacggtagcg atcacctggc ataggaatag cacaaaagac agctatgagg aaacctgcca
    17521 cgatttctgt tatttttaat accttatagc gcctacgatg ttgaacgctt ttctttaaaa
    17581 aatgagctat ctgtacgtct aatcgctctg tcaggtacat ttcttctggc gtcatattcg
    17641 taactccttt catttacttt gataatcata gtataacata tttgaatatc aaagtatagt
    17701 aaaaactgga ctataactta ttagacttcc tgcgaaacaa aacatggtat agtagttcta
    17761 tgaat
//
LOCUS       DAVHSH010000040        16064 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000040 DAVHSH010000000
VERSION     DAVHSH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.040"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            37..1041
                     /locus_tag="VVR08_001479"
     CDS             37..1041
                     /locus_tag="VVR08_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6075379.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            1110..1976
                     /locus_tag="VVR08_001480"
     CDS             1110..1976
                     /locus_tag="VVR08_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075380.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            1973..2731
                     /locus_tag="VVR08_001481"
     CDS             1973..2731
                     /locus_tag="VVR08_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075381.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            2821..4581
                     /gene="dnaG"
                     /locus_tag="VVR08_001482"
     CDS             2821..4581
                     /gene="dnaG"
                     /locus_tag="VVR08_001482"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6075382.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENGENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            4584..5693
                     /gene="rpoD"
                     /locus_tag="VVR08_001483"
     CDS             4584..5693
                     /gene="rpoD"
                     /locus_tag="VVR08_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU6075383.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVETGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            5707..6036
                     /locus_tag="VVR08_001484"
     CDS             5707..6036
                     /locus_tag="VVR08_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6075384.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            6151..7194
                     /gene="cpoA"
                     /locus_tag="VVR08_001485"
     CDS             6151..7194
                     /gene="cpoA"
                     /locus_tag="VVR08_001485"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU6075385.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            7210..8535
                     /locus_tag="VVR08_001486"
     CDS             7210..8535
                     /locus_tag="VVR08_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6075386.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            8566..8742
                     /locus_tag="VVR08_001487"
     CDS             8566..8742
                     /locus_tag="VVR08_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6075387.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            8801..8935
                     /locus_tag="VVR08_001488"
     CDS             8801..8935
                     /locus_tag="VVR08_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU6075388.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            8999..10309
                     /gene="obgE"
                     /locus_tag="VVR08_001489"
     CDS             8999..10309
                     /gene="obgE"
                     /locus_tag="VVR08_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU6075389.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPVPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            10319..10477
                     /locus_tag="VVR08_001490"
     CDS             10319..10477
                     /locus_tag="VVR08_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075390.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            11564..12823
                     /locus_tag="VVR08_001491"
     CDS             11564..12823
                     /locus_tag="VVR08_001491"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6075391.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            12839..13390
                     /locus_tag="VVR08_001492"
     CDS             12839..13390
                     /locus_tag="VVR08_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6075392.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            13383..14660
                     /locus_tag="VVR08_001493"
     CDS             13383..14660
                     /locus_tag="VVR08_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6075393.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            14676..15536
                     /locus_tag="VVR08_001494"
     CDS             14676..15536
                     /locus_tag="VVR08_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU6075394.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            15917..>16064
                     /locus_tag="VVR08_001495"
     CDS             15917..>16064
                     /locus_tag="VVR08_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU6075395.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKL"
BASE COUNT         4895 a         2758 c         3704 g         4707 t
ORIGIN      
        1 tgaaatatgt taaaggaaat aaaaaggaga aacagaatga aaaataaacg tttaattgga
       61 attattgctg cattagcagt cttagtagca ggaagcttga tttattcttc aatgaataaa
      121 tcagaagttc agaataataa ggatgagaag aaaataacca agattggtgt gcttcaattt
      181 gtgagccatc catcccttga tttgatttat aaagggatcc aagatggact tgcagaagaa
      241 ggatataaag atgatcaagt taaaattgat tttatgaact cagaaggtga ccaaagtaag
      301 gttgcgacaa tgagtaaaca attggttgca aatgggaatg accttgtggt tggtatcgca
      361 acaccagcag cccaagggtt ggctagtgca acaaaagacc taccggttat catggccgct
      421 attacagacc caattggtgc taacttggtt aaagatttga aaaaaccagg tggcaacgtt
      481 acaggggtat ctgaccacaa tccagctcaa caacaagttg aactcatcaa ggctctgaca
      541 ccgaatgtga aaacaatcgg agctctttac tcaagtagcg aagacaattc aaaaacacag
      601 gtcgaagaat ttaaggctta tgctgaaaaa gcaggtctga cagtggaaac atttgcagtt
      661 ccttcaacaa atgaaattgc ctcaactgtc actgttatga ctagcaaggt agatgctatt
      721 tgggttccaa ttgataacac cattgcatca ggatttccaa cggttgtctc tagcaatcaa
      781 agttctaaga aaccaattta tcccagtgcg acagctatgg tagaagtagg tggtttggca
      841 tcagttgtaa ttgaccaaca tgaccttggt gtggcaacag gtaaaatgat tgtgcaagtc
      901 ttgaaaggtg caaaaccagc cgatacccca gtcaatgtct tttcaactgg taagtcagtc
      961 atcaataaaa aaatagcaca agaactaggt attactattc ctgagtctgt tctcaaagaa
     1021 gcaggacaag tcatcgaata aataaggtag ggaggaggag actcttccca ttttttaaaa
     1081 agatgaatat agaaaggatt aaataaaata tgattgtttc cattatttct caaggatttg
     1141 tctgggctat tctaggtctg ggaatcttta tgacatttag gattttaaac tttccagata
     1201 tgacgacaga aggttccttc cctcttgggg gagctgttgc tgtcactttg ataaccaaag
     1261 gcgtgaatcc atttttagcg acacttgttg ctgtaggagc aggttgtttg gctggaatgg
     1321 cagcaggcct tctttataca aaagggaaga tcccaacctt gctctcaggg attttggtga
     1381 tgacttcttg tcactcaatc atgctcttga ttatgggacg tgcaaattta ggcctgcttg
     1441 gaaccaagca aattcaggat gttttgcctt ttgattcgga tttgaatcaa ctcttgacag
     1501 gtctcatctt tgtgagcatt gttattgctc tcatgctctt tttcttggac actaaactcg
     1561 gacaagccta tattgctaca ggggataatc ctgatatggc tagaagtttc gggattcata
     1621 ctggacgcat ggagctcatg ggcttggtct tatcaaatgg tgtgattgcc cttgcaggtg
     1681 ccctcattgc tcagcaagaa ggctatgccg atgtgtctcg agggatcggg gttatcgttg
     1741 tggggcttgc aagtttgatt attggagaag ttattttcaa gagtttgagc ttggcagagc
     1801 gtttggttac tatcgttgta ggttctatcg cttatcaatt tttagtgtgg gcagttatcg
     1861 cacttggctt taatacaagt taccttcgtt tatacagtgc tttgatttta gcagtctgcc
     1921 tcatgattcc aacatttaag caaacaatct tgaaaggagc caagttaagc aaatgacagc
     1981 aattgtagaa ttaaaaaatg caaccaaaat cgttaaaaat ggctttgatg aagaaaagat
     2041 tattttaaat gatgtttcct tagaaatttt tgaacgggac tttatcacga ttttgggcgg
     2101 aaatggtgct ggaaaatcaa ctctctttaa cactatagca gggaccttat cactaactag
     2161 tggaactatc cgtattttag gtgaagatct cactaagttt tcacccgaga agcgtgccaa
     2221 gtacctgtct cgtgtcttcc aagatccaaa gatggggaca gctccccgta tgacggtcgc
     2281 tgaaaatctt ttaatcgcca agtttcgtgg tgaaaagcgt ggattgttac caagacgctt
     2341 gactagctat aaggatgaat ttcaggcaac cattgaaaaa gtaggaaatg gtcttgagaa
     2401 acacttgaat acaccgattg agttcttatc aggtggacaa agacaggctt tgagtctctt
     2461 gatggcaacc ttgaagcgac ctgaattact cctgttagat gagcatactg ctgccctgga
     2521 tccaaagact agtgttgctt tgatggaatt gacagatgaa tttgttaaga aagatcagct
     2581 aacagccctt atgattactc atcatatgga agatgctctc aaatacggca atcgcttgat
     2641 tgtcatgaaa gaaggacgga ttatccaaga tttaaaccaa gaagaaaaag caaaaatgaa
     2701 aatctctgat tattatcaac tctttgaata aagtagggaa aatgagtgaa atggtttact
     2761 ttttttctga aataaagtat actatataaa gtaaactatg ataacatgga ggtattgtgt
     2821 atggttgaca aacaagtcat tgaagaaatc aaaaacaatg ccaacattgt ggaagtcata
     2881 ggagatgtga tttctttaca aaaggcagga cggaactatc tagggctctg tccttttcat
     2941 ggtgaaaaaa caccttcttt caacgttgta gaggacaagc agttttacca ctgttttggt
     3001 tgtggtcgct caggtgatgt ctttaaattc atcgaggagt accaaggggt tacctttatg
     3061 gaggctgtcc aaatcttagg tcagcgtgtc gggattgagg ttgaaaaacc gctttatagt
     3121 gaacagaagc cagcctcgcc tcaccaagct ctttatgata tgcacgaaga tgcagccaaa
     3181 ttttaccatg ctattctcat gacaacgact atgggagaag aggccagaaa ttacctttat
     3241 cagcggggtt tgacagatga agtgcttaaa catttttgga ttggtttagc acctccagaa
     3301 cgaaactatc tctatcaacg tttgtctgat cagtatcgtg aagaggattt actggattca
     3361 ggcctgtttt atctctcgga tgccaatcaa tttgtagaca cctttcacaa tcgcattatg
     3421 tttcccctga caaatgacca aggaaaggtc attgccttct caggtcgtat ctggcaaaaa
     3481 acggattcac aaacttctaa gtataaaaac agccgatcga ctgcaatttt taacaaaagt
     3541 tacgaattat atcatatgga tagggcaaaa agatcttctg gaaaagctag tgagatttac
     3601 ctgatggaag gattcatgga tgttattgca gcctatcggg ctggaatcga aaatgctgtg
     3661 gcgtcgatgg gaacggcctt gagtcgagag catgttgagc atctgaaaag gttaaccaag
     3721 aaattggttc ttgtttacga tggagataag gctgggcaag ccgcgacatt gaaagcattg
     3781 gatgaaattg gtgatatgcc tgtgcaaatc gtcagcatgc ctgataactt ggatcctgat
     3841 gaatatctac aaaaaaatgg tccagaagac ttggcctatc tattaacgaa aactcgtatt
     3901 agtccgattg agttctacat tcatcagtac aaacctgaaa acggtgaaaa tctgcaggct
     3961 cagattgagt ttcttgaaaa aatagctccc ttgattgttc aagaaaagtc catcgctgct
     4021 caaaacagct atattcatat tttagctgac agtctggcgt cctttgatta tacccagatt
     4081 gagcagattg ttaatgagag tcgtcaggtg caaaggcaga atcgcatgga aagaatttcc
     4141 agaccgacgc caatcaccat gcctgtcacc aagcagttat cggctattat gagggcagaa
     4201 gcccatctac tctatcggat gatggaatcc cctcttgttt tgaacgatta ccgtttgcga
     4261 gaagactttg catttgctac acctgaattt caggtcttat atgacttgct tggccagtat
     4321 ggaaatcttc ctccagaagt tttagcagag cagacagagg aagttgaaag agcttggtac
     4381 caagttttag ctcaggattt gcctgctgag atatcgccgc aggaacttag tgaagtagag
     4441 atgactcgaa acaaggctct cttgaatcag gacaatatga gaatcaaaaa gaaggtgcag
     4501 gaagctagcc atgtaggaga tacagataca gccctagaag aattggaacg tttaatttcc
     4561 caaaagagaa gaatggagta ataatggcaa caaaacaaaa agaagtaaca acatttgacg
     4621 tacaggtagc agaatttatc cgtaatcata agcaaaaagg gacagcaaca gatgatgaaa
     4681 ttaatgcaag tttggttatt ccttttacct tggacgctga tgggattgaa gatctcttgc
     4741 aacggattca ggatgcagga atttctatca cagataacga aggaaatcca agtgcgcgtg
     4801 ttcttagcaa tgaagaagaa ccagaactca gcgatgagga cttgattggg tcaacttctg
     4861 ctaaggtcaa tgaccctgtc cgtatgtact tgaaagaaat aggggtcgtt cctctcttga
     4921 ccaatgaaga ggagaaagag ttggcactgg ctgttgaaac tggtgatatc gaagccaaac
     4981 aacgtcttgc ggaagccaat cttcgtttgg ttgtttccat tgccaaacgc tatgtcggtc
     5041 gtggtatgca gttccttgac ttgattcaag aaggaaatat gggcttgatg aaggcggttg
     5101 acaagtttga ctattctaaa gggttcaagt tttcaactta tgcaacttgg tggattcgtc
     5161 aggctatcac tcgtgctatt gcggaccaag ctcgtaccat ccgtatccca gttcacatgg
     5221 ttgaaactat caataaattg gttcgtgaac agcggaatct ccttcaagaa ttggggcaag
     5281 atccgacacc agaacagatt gctgaacgaa tggatatgac acctgataag gttcgtgaaa
     5341 tcttgaagat tgcccaagaa ccagtatctc ttgaaactcc tatcggtgaa gaggacgata
     5401 gccaccttgg agactttatc gaagatgaag tgattgaaaa tccagtggat tatacgactc
     5461 gtatcgtctt gcgtgagcaa ttggatgaaa tcttagatac tcttacagac cgtgaagaaa
     5521 atgttctgcg tctacgtttt ggactagatg atggaaaaat gcgcacactt gaagatgtgg
     5581 ggaaagtctt taacgtaact cgtgagcgta tccgtcagat tgaagcaaag gctttgagaa
     5641 aactacgcca accaagtcgt agcaaaccgc ttcgtgattt tattgaagac taagagtgag
     5701 gaaaatatgg cttatacaga agagcaaatt gaaaacatca aaacacggat tttaacagcc
     5761 ttggaagaag tcatcgaccc tgagttggga atcgatattg tcaatcttgg tttgatctat
     5821 gagattcgtt ttgacggtga cacagggcaa acagagattg acatgacttt gacaactatg
     5881 ggttgtccct tagcagacct tttgacagac cagatttatg atgctatgat agaggttcca
     5941 gaagtaacgg atactgaggt taaattagtc tggtatccag cctggacagt tgaaaaaatg
     6001 agtcgctatg cccgcattgc cctaggcatt aagtaaacat ataaaagcat gtgagagact
     6061 gttggaaaag cgaggaaatt tcccctcttt tcctctagtc tctcctttct tttgctgatt
     6121 ttattcaaag aaaatgatat aatagtagtt atggagaaaa agaaattacg catcaatatg
     6181 ttgagttcaa gtgagaaagt agcaggacag ggagtttcag gtgcttaccg tgaattagtt
     6241 cgtcttcttc accgtgctgc caaggaccaa ttgattgtta cagaaaatct tccaatcgag
     6301 gcagatgtga ctcactttca tacgattgat tttccctatt atttatcaac cttccaaaag
     6361 aaacgctcag ggagaaagat tggctatgtg catttcttgc cagctacact tgagggaagt
     6421 ttgaaaattc catttttctt aaagggaatt gtgaaacgct atgtattttc tttttacaac
     6481 cggatggagc acttggttgt ggtcaatcct atgtttattg aggatttggt agcagctggt
     6541 attccacgtg aaaaagtgac ctatattcct aactttgtca acaaggaaaa atggcatcct
     6601 ctaccacaag aagaggtagt cagactgcgc acagatcttg gtcttagtga caatcagttt
     6661 atcgtagtag gtgctgggca agttcagaaa cgtaaaggga ttgatgactt tatccgtctg
     6721 gctgaggaat tgcctcagat tacctttatc tgggctggtg gcttctcttt tggtggtatg
     6781 acagatggtt atgaacacta taagaaaatt atggaaaatc cccctaaaaa tttgattttt
     6841 ccaggcattg tatcgccaga gcggatgcgc gaattgtatg ctctagcgga tcttttcttg
     6901 ttgcctagtt acaatgagct ctttcctatg actattttag aagctgcgag ttgtgaggct
     6961 cctattatgt tgcgtgattt agatctctat aaggtaattt tggagggaaa ttatcgggcg
     7021 acagcgggta gagaagagat gaaagaggct attttggaat atcaagcaaa tcctgctgcc
     7081 ttaaaagatc tcaaagaaaa ggctaagaat atttccagag agtattctga agagcatctg
     7141 ttacaaatct ggttggactt ttatgagaaa caagccgctt tagggagaaa gtaaaaagtg
     7201 aggtaatcta tgcgaattgg tttatttaca gatacctatt ttcctcaggt ttctggtgtt
     7261 gcgaccagta ttcgaacctt gaaaacagaa cttgaaaagc agggacatgc tgtttttatc
     7321 tttacgacga cagataagga tgtcaatcgc tacgaagatt ggcaaattat ccgcattcca
     7381 agtgttcctt tctttgcttt taaggatcgt cgctttgcct accgaggttt tagcaaggca
     7441 cttgaaattg ctaaacagta tcagctagat attatccata ctcagacaga attttctctt
     7501 ggcctgttgg ggatttggat tgcgcgtgaa ttgaaaattc cagtcatcca tacctatcac
     7561 acccagtatg aagactatgt ccattatatt gctaagggga tgttgatccg gccgagtatg
     7621 gtcaagtatc tggttagagg tttcctgcat gatgtggatg gggttatttg tcctagtgag
     7681 attgtccgtg acttgctatc tgattataag gtcaaggttg aaaaacgggt cattcctact
     7741 gggattgaat tagccaagtt tgagcgtccg gaaatcaagc aggaaaattt gaaagaactg
     7801 cgtagtaaac tagggattca agatggtgaa aagacgttgc ttagtctttc gagaatctcc
     7861 tatgaaaaaa atattcaagc agttttagca gcctttgctg atgttctgaa agaggaagac
     7921 aaggttaaac tggtagtagc tggggatggc ccttatctga atgacctcaa agagcaagct
     7981 cagaacctag agattcaaga ctcagtcatc tttacaggga tgattgctcc tagtgagacg
     8041 gctctttact ataaagcggc ggatttcttc atttcggcat cgacaagcga aacgcaaggt
     8101 ttgacctact tggaaagctt agccagtgga acacctgtca ttgctcacgg aaatccttat
     8161 ttgaacaacc tcatcagtga taaaatgttt ggaaccttgt actatggaga acatgatttg
     8221 gctggtgcta ttttggaagc cctgattgca acaccagaca tgaatgagca taccttatca
     8281 gagaaattgt atgagatttc agctgagaac tttgggaaac gagtgcatga gttttatctg
     8341 gatgccatta tttcaaataa cttccagaaa gatttggcta aagatgatac ggtcagtcag
     8401 cgtatcttta agacagtttt gtatcttccg caacaggtgg ttgctgtacc tgtaaaagga
     8461 tctagacgca tgttgaaggc ttcaaaaaca cagttgatca gtatgagaga ctattggaaa
     8521 gaccatgaag aatagaaaga ggaacagcta tgaaaaaaac aattaatgag aagcggtcgt
     8581 gataaaaaga ttgcgggtgt ttgtgctggg gtggcccatt atctggatat ggatccgact
     8641 atcgttcgag tcatttgggg tgttcttact tgctgttacg gagctggaat tgtagcttac
     8701 attattttat ggattatcgc accagtagca actgactatt gaaaactagc tcaattcatg
     8761 ctaagataat agaaaataga atgtaacgaa ggagagaaaa atggcatttg gagataatgg
     8821 aaatcgtaaa aaaactatgt ttgagaaaat aaccttgttt atcgtgatta tcatgctagt
     8881 agcaagttta ttgggaattt ttgcaactgc aattggtgcc ctcagtaatc tataaaatag
     8941 attcaagaaa atttagtgac tgggatttcc cagccctttt ttaaagtgag aagaaataat
     9001 gagtatgttt ttagatacag ctaagattaa ggtcaaggct ggtaatggtg gcgatggtat
     9061 ggttgccttt cgtcgtgaaa aatatgtccc taatggaggc ccttggggtg gtgatggtgg
     9121 tcgtggaggc aatgtggtct tcgttgtaga cgaaggacta cgtaccttga tggatttccg
     9181 ctacaatcgt catttcaagg ctgattctgg tgaaaaaggg atgaccaaag ggatgcatgg
     9241 tcgtggtgct gaggacctta gagttcgagt accacaaggt acgactgttc gtgatgcgga
     9301 gactggcaag gttttaacag atttgattga acatgggcaa gaatttatcg ttgcccacgg
     9361 tggtcgtggt ggacgtggaa atattcgttt cgcgacacca aaaaatcctg taccggaaat
     9421 ctctgaaaat ggagaaccag gtcaggaacg tgagttacaa ttggaactaa aaatcttggc
     9481 agatgtcggt ttagtaggat tcccatctgt agggaagtca acacttttaa gtgttattac
     9541 ctcagctaag cctaaaattg gtgcctacca ctttaccact attgtaccaa atttaggtat
     9601 ggttcgcacc caatcaggtg aatcctttgc agtagccgac ttgccaggtt tgattgaagg
     9661 ggctagtcaa ggtgttggtt tgggaactca gtttctccgt cacatcgagc gtacacgtgt
     9721 tatccttcac atcattgata tgtcagctag cgaaggccgt gatccatatg aggattacct
     9781 agctatcaat aaagagctgg agtcttacaa tcttcgcctc atggagcgtc cacagattat
     9841 tgtagctaat aagatggaca tgcctgagag tcaggaaaat cttgaagaat ttaagaaaaa
     9901 attgtctgaa aattatgatg aatttgaaga gttaccagct atcttcccaa tttctggatt
     9961 gaccaagcaa ggtctggcaa cacttttaga tgctacagct gaattgttag acaagacacc
    10021 agaatttttg ctctacgacg agtccgatat ggaagaagaa gcttactatg gatttgacga
    10081 agaagaaaaa gcctttgaaa ttagtcgtga tgacgatgcg acatgggtac tttctggtga
    10141 aaaactcatg aaactcttta atatgaccaa ctttgatcgt gatgaatctg tcatgaaatt
    10201 tgcccgtcag cttcgtggta tgggggttga tgaagccctt cgtgcgcgtg gagctaaaga
    10261 tggggatttg gtccgcattg gtaaatttga gtttgaattt gtagactagg agactggtat
    10321 gggagataaa ccgatatctt tccgagatgc ggatggtaat tttgtttccg ccgcagacgt
    10381 ttggaatgaa aagaaattgg aagaactatt taatcgtctc aatccaaatc gtgccttgag
    10441 attggcacga actaaaaagg aaaatccatc tcagtaaaga agctaaaaaa tcccgtgcct
    10501 tatcagacac gggattttgt ggtacgacag gcatgtatag caaactgaat ctggaatagc
    10561 acagcatatc ttctaaaata ttgttataaa ttgatttgaa tttcaaaatt aaattgtttg
    10621 attcttattt caatttgtta tagtatatct gatgtcaaag ttctcggcga atcaaatagc
    10681 gattcccaag cctgactatc gtgaggtagc ggattaaaat ggtctgggga tagaccgttt
    10741 taagtctgac gctggaaata agaattgtca gaagaaggga tagcgaaatc gtggctctac
    10801 gaacaggaac gtgataataa ggcgtatata gcggataaga gggcctcaaa ctctaaagtc
    10861 caaaaaggta gtcgtaacct atatgcgtaa atcacgagag taattgaatt cgtactaaga
    10921 ttttctattt tcactgtaac cttttaacgt cctcatatct tgtatacacg aggaaagatg
    10981 tacgacttat cccgtgaggt ctatcactat aaagagaaaa cgacagatag aagtgatcct
    11041 gagtcacggt tatctttaaa atagattgtc tgataggatg ctagcctgaa aacgtcttgt
    11101 tcatgaaata taggacggta tgtataaaac gcttctgtga actgagagaa gggggagaag
    11161 ttcttgctaa aatttagttg aacagccgta ttccgatatt tagataagag atctagtctt
    11221 agctcctact cggtttcagg ggataaaaaa ggggcaatag cgattcgaga aagattatac
    11281 tcttcgaaaa tctcttcaaa tcacgtcaat atcgccttgc cgtacgtgta ggatactgac
    11341 tacgtcagtt ccatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagtttcct
    11401 agtgtgatct ttgattttta ttgagtatta gtaattcagt tactaactcg tcaactctga
    11461 tttatccaat aaaattgaaa aggatggaaa aaaggataaa tttatgatat actttatttt
    11521 gaagacctta ttagaaatct tgaaagagta ttgaaaactt agaatgagaa aaattgttat
    11581 caatggtgga ttaccactgc aaggtgaaat tactattagt ggtgctaaaa atagtgttgt
    11641 ggccttaatt ccagctatta tattggctga tgatgtggtg actttggatt gtgttccaga
    11701 tatttcggat gtagccagtc ttgtcgaaat catggaattg atgggagcta ctgttaagcg
    11761 ttatgacgat gtcttggaga ttgatccaag aggtgttcaa aatattccaa tgccttatgg
    11821 taaaattaac agtcttcgtg catcttatta tttttatggg agcctcttag gccgttttgg
    11881 tgaagcgaca gttggtctac cgggaggatg tgatcttggt cctcgtccga ttgacttaca
    11941 ccttaaggcg tttgaagcta tgggtgccac tgctagctac gagggagata acatgaagtt
    12001 atctgctaaa gatacaggac ttcatggtgc aagtatttac atggatacgg ttagtgtggg
    12061 agcaacgatt aatacgatga ttgctgcggt taaagcaaat ggtcgtacta ttattgaaaa
    12121 tgcagcccgt gaacctgaga ttattgatgt agctactctc ttgaataata tgggtgccca
    12181 tatccgtggg gcaggaacta atatcatcat tattgatggt gttgaaagat tacatgggac
    12241 acgtcatcag gtgattccag accgcattga agctggaaca tatatatctt tagctgctgc
    12301 agttggtaaa ggaattcgta taaataatgt tctttacgaa cacctggaag ggtttattgc
    12361 taagttggaa gaaatgggag tgagaatgac tgtatctgaa gacagcattt ttgtcgagga
    12421 acagtctaat ttgaaagcaa tcaatattaa gacagctcct tacccaggct ttgcaactga
    12481 tttgcaacaa ccgcttaccc ctcttttact aagagcgaat ggtcgtggta caattgtcga
    12541 tacgatttac gaaaaacgtg taaatcatgt ttttgaacta gcaaagatgg atgcggatat
    12601 ttcgacaaca aatggtcata ttttgtacac gggtggacgt gatttacgtg gggccagtgt
    12661 taaagcgacc gacttaagag ctggggctgc actagtcatt gctgggctta tggctgaagg
    12721 taaaactgaa attaccaata tcgagtttat cttacgtggt tattctgata ttatcgaaaa
    12781 attacgtaat ttaggagcgg atattagact tgttgaggat taaaccgtag aggtgtttat
    12841 gaatatttgg accaaattag caatgttttc tttttttgaa acggatcgct tgtatttgcg
    12901 tcctttcttt tttagtgata gtcaggactt ccgcgagata gcttcaaatc cagaaaatct
    12961 tcaatttatt ttcccaacgc aggcaagtct ggaagaaagt caatatgcac tggccaatta
    13021 ctttatgaag tcccctttgg gagtgtgggc aatttgtgac cagaaaaatc aacaaatgat
    13081 tggttctatt aaatttgaga agttagatga aatcaaaaaa gaagctgagc ttggctattt
    13141 tttgagaaaa gatgcttggt cgcaaggatt tatgacagag gttgttagaa aaatttgtca
    13201 gctttctttt gaggaatttg gcttaaaaca attatctatc attacccacc ttgaaaatga
    13261 agctagccaa agagttgctc ttaagtctgg atttagtttg ttccgtcagt ttaagggaag
    13321 tgatcgttac acaagaaaaa tgcgggatta tcttgaattt cggtatgtaa aaggagagtt
    13381 caatgagtaa gcatcaggaa attctaagct atttggagga attaccagta ggtaaaaggg
    13441 tcagtgttcg tagcatttcg aatcatctag gagttagtga tggaacagcc tatcgggcta
    13501 ttaaagaagc tgaaaaccgt ggaattgtgg agacccgtcc tagaagtgga acaattcgtg
    13561 ttaaatccca gaaagttgct atagagagat taacgtttgc tgaaattgca gaagtgactt
    13621 cttctgaggt tctggctggg caagaaggtt tagagagaga atttagtaag ttttcaattg
    13681 gtgccatgac tgaacaaaat atcttgtctt accttcatga tggggggctc ttgattgtcg
    13741 gagaccgaac ccgtattcag ttgctagcct tggaaaatga aaatgcagtt ctggttacag
    13801 ggggatttca ggttcatgat gatgtgctta aactggccaa tcaaaaaggg attcctgttc
    13861 taagaagtaa gcatgatacc tttaccgtcg cgaccatgat caataaagcc ttgtcaaatg
    13921 tccaaatcaa gactgatatt ctgacagttg agaaacttta tcgccctagt catgagtatg
    13981 gttttctgag agagacagat acagttaaag attatttgga cttggttcgt aagaatcgta
    14041 gcagccgttt ccctgttatc aatcaacatc aggtcgttgt tggcgttgta accatgagag
    14101 acgctggtga taaatcacca agcacgacaa ttgataaggt tatgtctcgt agtctatttt
    14161 tggttggatt atcgacaaat attgccaatg tgagtcaacg gatgatcgca gaagactttg
    14221 aaatggtacc agttgttcga agcaatcaaa ctttgcttgg cgttgtgacg cgacgagatg
    14281 tcatggagaa gatgagccgt tcccaagttt cggctctacc aactttttct gagcagattg
    14341 gacaaaagct ctcttatcac catgatgaag tagtcattac agtggaaccc tttatgctag
    14401 aaaaaaatgg agttttggct aatggtgtat tggcagaaat tctgacccac atgacccaag
    14461 atttagttgt taatagtggt cgcaatctca ttatcgagca gatgctgatc tactttttgc
    14521 aggctgttca gatagatgat atattgcgca ttcaggcacg gattattcat catacgagac
    14581 ggtcagctat aattgattac gatatttatc atggtcacca gattgtttca aaagcaaatg
    14641 tgactgttaa aattaattag aaactaggag aaaagatgat aacattaaaa tcagctcgtg
    14701 aaatcgaagc tatggacaag gctggtgatt ttctagcaag tattcatata ggcttacgtg
    14761 atttgattaa gccaggcgta gatatgtggg aagttgaaga atatgtccgc cgtcgttgta
    14821 aagaagaaaa tttccttcca cttcagattg gggttgacgg tgccatgatg gactatcctt
    14881 atgctacctg ttgctctctt aacgatgaag tggctcacgc tttccctcgt cattatatct
    14941 tgaaagatgg tgatttgctc aaagttgata tggttttggg aggtcccatt gctaaatctg
    15001 acctaaatgt ctcaaaatta aacttcaaca atgttgaaca aatgaaaaaa tacactcaga
    15061 gctattctgg tggtttagca gactcatgtt gggcttatgc tgttggtaca ccgtccgaag
    15121 aagtcaaaaa cttgatggat gtaaccaaag aagctatgta caagggtatt gagcaagctg
    15181 ttgttggaaa tcgtatcggt gatatcggtg cggctattca agaatacgct gaaagtcgtg
    15241 gttacggtgt agtgcgtgat ttggttggtc atggtgttgg cccaactatg cacgaagaac
    15301 caatggttcc taactatggt attgcaggtc gtggactccg tcttcgtgaa ggaatggtct
    15361 taaccattga accaatgatc aatacaggcg attgggaaat tgatacagat atgaaaactg
    15421 gttgggcgca taagaccatt gacggtggat tgtcatgtca gtatgaacac caatttgtca
    15481 ttacgaaaga tggacctgtt atcttgacta gccaaggtga agaaggaact tattaataaa
    15541 aagtgaaaag actactggaa gtttattttg ataaaaaatc cagtagatct tttcataata
    15601 aaacgcattg tatcaagtgt taggggctga tatcatgcgt ttttctgctt ttaagatttt
    15661 ttccaactct gtttgtaagc gcatcataac aaagggtcta ggattcaggg ctctcctcct
    15721 atatactatt agtaaagtaa aactaagaga ggatatttta gtgtcgcagt ctattgttcc
    15781 tgtagagatt ccacaatatt gtcgttttga ttctaaaaag agaaatggaa ttctgtttaa
    15841 cgttcgtatt gccaatctta aatttacctt ttttagatta gacttcctgc gaaataaaat
    15901 atggtatagt agttctatga atgatgaagc aagtaaacaa ctaactgatg cacgatttaa
    15961 gcgtcttgtt ggtgttcagc gcacgacttt tgaagagata ttagctgtat taaaaacagc
    16021 ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaa
//
LOCUS       DAVHSH010000041        15194 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000041 DAVHSH010000000
VERSION     DAVHSH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.041"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            204..686
                     /locus_tag="VVR08_001496"
     CDS             204..686
                     /locus_tag="VVR08_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009431600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEU6075396.1"
                     /translation="MEDVEKKILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDID
                     RYKVVSGKLKKLLSDKEKLSPKKWNEEKILLMSNLEEINKEKDKIKDEYQEINHIKYS
                     VDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYREMMKNKKMDQER
                     "
     gene            760..933
                     /locus_tag="VVR08_001497"
     CDS             760..933
                     /locus_tag="VVR08_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075397.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            1119..1646
                     /locus_tag="VVR08_001498"
     CDS             1119..1646
                     /locus_tag="VVR08_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU6075398.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1773..2501
                     /locus_tag="VVR08_001499"
     CDS             1773..2501
                     /locus_tag="VVR08_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU6075399.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            3185..3346
                     /locus_tag="VVR08_001500"
     CDS             3185..3346
                     /locus_tag="VVR08_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075400.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            3438..5117
                     /locus_tag="VVR08_001501"
     CDS             3438..5117
                     /locus_tag="VVR08_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6075401.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADILSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREEFLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            5385..5951
                     /locus_tag="VVR08_001502"
     CDS             5385..5951
                     /locus_tag="VVR08_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075402.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            6272..6460
                     /locus_tag="VVR08_001503"
     CDS             6272..6460
                     /locus_tag="VVR08_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU6075403.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            6522..7280
                     /locus_tag="VVR08_001504"
     CDS             6522..7280
                     /locus_tag="VVR08_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6075404.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            7338..8192
                     /locus_tag="VVR08_001505"
     CDS             7338..8192
                     /locus_tag="VVR08_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU6075405.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            8304..9188
                     /locus_tag="VVR08_001506"
     CDS             8304..9188
                     /locus_tag="VVR08_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU6075406.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            9351..10478
                     /locus_tag="VVR08_001507"
     CDS             9351..10478
                     /locus_tag="VVR08_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU6075407.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLFEIIKNIKNLVINLN"
     gene            10427..11763
                     /locus_tag="VVR08_001508"
                     /pseudo
     CDS             10427..11763
                     /locus_tag="VVR08_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(11804..12655)
                     /locus_tag="VVR08_001509"
     CDS             complement(11804..12655)
                     /locus_tag="VVR08_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEU6075408.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLIQYIRKQYSLQNINNIQSLLSDS
                     SNYTLDSFEKTMVKSILHTMDSRIIPSDDELLQLADYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCFILSIDKEEFSNCSYLINEIK
                     GLLENELNFYEQTVFLYATGYYEFKRQLSSGIETMKQAIQVLDILGEDKLKLHYTSHF
                     DKLVNNK"
     gene            12737..12808
                     /locus_tag="VVR08_001510"
     CDS             12737..12808
                     /locus_tag="VVR08_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEU6075409.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            12912..13781
                     /locus_tag="VVR08_001511"
     CDS             12912..13781
                     /locus_tag="VVR08_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HEU6075410.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKNLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            13768..14490
                     /locus_tag="VVR08_001512"
     CDS             13768..14490
                     /locus_tag="VVR08_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU6075411.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            14563..15018
                     /locus_tag="VVR08_001513"
     CDS             14563..15018
                     /locus_tag="VVR08_001513"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075412.1"
                     /translation="MIVLYDSFDSIVNCFDKLKGQYILLSVAFESSIKNYSWKDFNFE
                     YHKRIEIVDSFHSFTKGMVLIENCNYKINRAIIQPATEILMLNYLKKKSMDLRIDFTH
                     SKVMANKKFLEEGYRFSIVSQETIINNDDIIICETFSPEMIWCLYRVKG"
BASE COUNT         5878 a         1977 c         2891 g         4448 t
ORIGIN      
        1 aaattcaaaa agaaaaaagt aaatatctaa aaggatatgc aaaaactaat aaagaaaaat
       61 atgacttcaa aaagctaaca agtgcatata gttatttaag aaaaaacaac atagaaacca
      121 taggtcagtt acaaacaaaa atagaaactt taaagtctaa tagttatagg ctaaataaaa
      181 aagcaaagac aatccataaa gaaatggaag atgtagaaaa gaaaattcta tactatgaaa
      241 tctacaaagc caaaaaagaa gtttatgaag aatatcaaaa gaaaaatata ttcacaaaag
      301 aagcatttta taacaaacat aagaaagata tagaccgata taaagtagta agtgggaaat
      361 taaaaaaact cctatcagat aaggaaaaac taagtcctaa aaagtggaat gaagaaaaaa
      421 ttcttttaat gtcaaatctt gaagaaataa ataaagaaaa agacaagata aaagatgaat
      481 accaggaaat taatcatata aaatattcag tagattttgt aaacaaagaa cttggtatag
      541 atttatccat agaaatagat aagctaataa aacagggaga aaaaccaagt gtaatagcac
      601 agattaaaaa gttccaagac caagtcaata aagataatga atacagagaa atgatgaaaa
      661 acaagaaaat ggatcaagaa agataagacc tggtaaaaat atcttatcca agctataata
      721 tgaccaaaca actaaagtca gatctaggag gtaatagaga tgaataaaag gcaagagcta
      781 atagatgaac tcataaaagc aaatgaagat ggaacataca aaacctataa aagcacagaa
      841 gaaataaaag caatgaacaa tgaagaaata cagattatat attctaacat gaaaaactat
      901 ctatcagaca aaagaacaca cataaactat taaaggtgga aaggtagtgt aagctatttt
      961 taaaagtata aaaggtacaa agacctaaga aatatataaa aacatcaaaa taaagtattc
     1021 caccaccaag aacaataaaa taaaaacaag caaagggaag tatagaaaaa ttaaaaccta
     1081 tacttccctt ttttaattca aacaaaggag agaaaagcat gataaacgaa gaaataagca
     1141 aggaagcagg tcaagcagca caaaccataa tatcatacac aataaaggca acaaaagaat
     1201 caatcaattt agaaaaagaa ataagaaaaa agatgaatga aactttagaa aaagcaaatg
     1261 gaaacttaaa aagtcttatg ggcgatgaaa tgaaaataaa agacctctac aagaaaggac
     1321 aactagaaaa tataagcata gatcaaatcg acctcaaaga cttaaaaaaa gaactaaaca
     1381 aacttggagt aagtttctca gtaatgaaaa acaaagaaag caaaaactat gaaatattct
     1441 tccaagccaa agacataaaa gtaatggaat atgcctttaa gcaagtcata gccaaggaaa
     1501 ataaaaaaga aaaagaaagt atcctaaaac aaataaagaa atacaaagac ctatccaaaa
     1561 acaaagataa gacaaaagaa aaaggaaaaa ggaaagtaaa agaaaaagta aaaccaaaca
     1621 aaaaagatat gaccagagaa atctaaaggg agtaacgaaa agttacaccc ttaaataacc
     1681 ataataacaa gacttccgaa aaacagaagt ccagaattcc gaaaatcgga aatcaagaat
     1741 ttcgattatc gaaaatcaag aaaggagcag atatggcaac aaacaaaaga tactattgga
     1801 taaaattaaa agaagaattt ttcacagaca aaaggataaa aaggttaagg agaatatctg
     1861 gaggagatac ctatacgata atctacctaa aacttctact actaagccta aaagatgagg
     1921 gcaaactcta ttatgacgga gtagaaagtg attttataaa agagttagca ctaaccatag
     1981 atgaaacaga cgatgatgta atggtaacag taaattattt aatcaatcaa ggcttattag
     2041 aagttgtaac agaaaatgat gaatactacc taactgaaat accaaactta atcggatcag
     2101 aaacagcctg ggcagagaaa aaaagaagat acagacaaaa taaacagagg acattgtcct
     2161 taatgagtcc aacccatgtc cgacaagaga tagagataga gaaagatata gagatagata
     2221 aagagagaga gggagagata gataaaaagt ccacccccat tttttatgga gaattcaaaa
     2281 atgtaaggtt aagcaaagaa gaatataaaa atctaaaaga aaaattaaac tcacacacag
     2341 atataatgat aaataaacta tccagataca tggaaagcag tggtaagacc tatcaaaacc
     2401 actatgtgac aatcttaaaa tggtatgaag aagataaaga caaactaaga cagaaaggtt
     2461 taaataaaaa aatgaattat gatgtaggag aatctttata gataaaaaga ggtggaaagg
     2521 cactattaaa gactttaagt ttaaaaaggt atcaaagtat gccagagata aaaaaatata
     2581 aatatgacac tttaaaggcg attagaaaat taaagaaatg ctagaagact tttagatgac
     2641 agttaccaag agggtctaat tttcactgct acttatgcag taggaattgg acctttttat
     2701 ataagcaaat tctatttcaa aattggttac caagaaagac ttcttttcac tgttaagtat
     2761 aagagggtaa tttatagaat tttgttacat caagataaat attttctgat ggtcaaattt
     2821 taaaaagatt aataactctc gataaatttt gaaccttaac aattgaatag accaagacaa
     2881 gacgttaatt atttttggag cgtaataacc tatccgtcaa gatctttcgg ctgaataatt
     2941 cggcaaaaaa agttctgcta agcaaaaaga aagtgagcga taagtaagag tttgaatata
     3001 gggagggata ccctatccgc tatgaagaaa atgaggataa tgatacttct aaggttgaag
     3061 caggctcatc cggaatagag gcggaggtga gattcctatg ttgctaatcc aaagcacttg
     3121 tcaatgtcaa aaaacttaat taaacaaata attattagat ataaaacttt agaggaggta
     3181 tatattggac aatgactgga atggattggc tgatttaata gcaaatctga ttgcaaaata
     3241 tgctggtgct ttagatttag ataatctacc cgatccaacg ccagcaaaaa atcaagagat
     3301 gaaaaatagt tttgacatgg caaaaacaca aattgagacg gactaataaa agtgttataa
     3361 tatacttgaa atgatagtcc aaacttaaat taaaaaaatt atatatgata tagaaaaatt
     3421 atattgaggt taatactatg tcaaaagaaa aaataaaagt atacctctat acacgagtat
     3481 ctacgtcaat acagatagag gggtattcgt tagaggcaca aaaatcacga atgaaagctt
     3541 ttgctattta caatgattat gaaattgttg gagaatatga agatgccggg aagtctggca
     3601 agtctattga aggtagaata cagttcaatc gaatgatgga agatataaaa tctggaaaag
     3661 atggagtatc ttttgttctt gtgtttaagt tatcaagatt tgcaagaaat gccgctgata
     3721 ttctttctac acttcagata atgcaggatt atggagttaa tcttatctgc gttgaagatg
     3781 gcattgattc atctaaagat gctgggaaac taatgatttc tgttttatca gctgtggctg
     3841 aaatagaaag agaaaacatc cgtattcaaa caatggaagg tcgcattcaa aaagcaaggg
     3901 aaggaaaatg gaatggtggc tttgctccgt atggatataa acttgaagac ggcaagctgt
     3961 ttataaatga ggaagaggca gttgcaataa gaacgatttt cgaccagtat gtaaatacta
     4021 cgataggagc caatgggata tctaaatact tagagaatca tggaattaga aaaatcccaa
     4081 gacagaatgg taagaatcct ttgtttgatg caggtcttat aagaaagata ttaaagaatc
     4141 ctgtatataa tgggaaaata gcatttggaa gaagaacttt agaaaaagtt catggtacaa
     4201 gaaatgaata taagcaggtt gaacaagatg aatatctaat atctgaaggg atacatgaag
     4261 ctatagtttc cgatgaagtt tggcaagctg ctcaggttaa gctaaaatct caagcaaaga
     4321 aatatgagca tgtgaataaa ggaaaagata cacgcacaca cttgctttct ggaattgtaa
     4381 aatgcccgat atgtggagtg ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg
     4441 gcacaaagta taaagatttt tattactatg gttataagca taggcagatg ataagaggtc
     4501 ataagtgtac attcagtaag caaattagag aagaattttt agatgatgct gttgcagagg
     4561 tgattgtcaa gatagtaagt aatccgaaat ttgcttctat gatgcaagaa aaaatcaaca
     4621 tgaaggtgga tacctctgaa atagaaaaag aaatagataa ttaccaaaag gaattgagaa
     4681 agagtcattc tacaaagttt aagctaattg aggaaataga taatttagat gttgaagata
     4741 agcattataa gagaaggaaa caggatttag atgatagact atatcgtatg tatgacaaaa
     4801 tagatgaatt agaatcatca ctaattgatg cgaaagcaaa gaaacagact attgaagctg
     4861 aaaagcttac aggagataac atatataagg ttctgatcta ttttgataag ctctataaag
     4921 tcatgaatga tgtagagcgt aggcagttaa tttcagcttt gatttctgaa attcaagttt
     4981 atgaagaaaa acaatctaac ggacaatggc taaaatccat tacttttaag ctaccaatta
     5041 tagaagaaaa tctcaacata ggtttggata atgatgaaca agttgaatgt gtaagtttat
     5101 tagagaaacg tagttaatcc tcaaaaggtt ccccaaacct tttgagtccc actgacgcat
     5161 cacgctgagg cggtatcact gcttgtacga gttgaagcat cagcgaagta aaagtagatg
     5221 ttcagccaat gcgacgaggt gagaccgaag gtcgataagg tgtgttctgg gtataggact
     5281 cgtaaagtaa gtaggaaata tgatgagatg atacagagag cctgaattgg tcaggtgacg
     5341 tgcttattta cattagcctg ataatgaaaa tggagagatt atcgatggtt atattggaat
     5401 tgtaccaaaa tgattattct aaagatttag tagcatttga ttccatagaa gatgggaaag
     5461 cctttgtagc tcaaatcccg ggatacactc tggaaacaga agatggtttt gaagtggagt
     5521 attttaatcc taaaaacata ccggattata tggaaattat ttttaacgga aatattgttc
     5581 ctttatctaa atttatgttc gatcctgagg aaaatgtaaa cattatttgg aaagagattt
     5641 caaatttatc cctcaaaaat gatagagtga tcgaaggata ttcaaaaatt gatgcatatg
     5701 tcgttaacaa ccatgaagtt aaagcctatg tcgaaacaag agaaacgaac tatcgtaaag
     5761 caaaagactt cttagaaagc cgcggatatg aaatcgacag aagctttttc ggaagtgaag
     5821 acggtgaagc gattctttac agaaaaaaag ggatcgaagt ttggcatttc ttgtgtcact
     5881 tagacccaat gtttgtagag attgaagatg tagaaggata tgttaaagaa gaagttggag
     5941 agattcaata gtcaaccaaa gttccttgtg agtatatacc tttgctagta aaagagtcaa
     6001 aacgttataa cgaagggggg aagaaaaccc ttgagtgtaa gtctttttct tgtttagagg
     6061 gaaagtatta gagtagccgc tcataattta tactagattt gataactgat ttgagacaga
     6121 ttttatttct ataaatattg tgaaaatttt ttaataccaa agatttaaag ttactgtgtt
     6181 aaaaatcctc tccactttta aactaatgta ttataaaagc cagttgacac aagtgttaca
     6241 cctatgatag aattaacttg aggtgatgaa aatggcaacc gataaaaata gaataatgat
     6301 tagcttggat gataaaaatc tagagaaact tgaaaattta gtagaagatg ctagagatag
     6361 aaggggaatg cgactaacaa agtcccaggt tattgaatta ctcctaaata ccgttgatta
     6421 tttcgatgat attatggggg ctatttactc aaaaaaataa gagcaaaatt gctattattt
     6481 tttacaaatt ggtgtaacac tagtgatata ggagtgatga aatggttgtt tatattagac
     6541 aaagtaaatt accaagtgag gtttcaatta ataaatacaa tgctcaagta ggtgcctact
     6601 tacaaggaga agaagttatt ttatatcaat ctttttctga aataaaagag ttaacaagtg
     6661 aagatatagt tgtagattat ataatggaga ctagagcatt actaaaaatg atgggcttaa
     6721 acgttccggt tcatgactat cctattgagc ttaaagagtt ttatggtcga aagatttatg
     6781 ctggtatttt aggagagatt gtgaatatac ctgataattg gggaaaattt attaagccta
     6841 aagctggttc aaaagtcttt actggaagag ttgttaatgg aacccatgat ttaataggta
     6901 ttggtctacc tttcgactat cctatatgga ttagtgaggt tgtagaattc atagctgaat
     6961 ggcgttgttt tgtgttagat ggtcgcgtat tagatgttcg accctataca ggtgattatc
     7021 atgcacaatt tgatgcaagt gtaattgatg aagcgatatc atgttggaaa gatgcgccaa
     7081 tagcttatgg actagatatc ggtgttactc gcgatggcag aacacttgtt gttgaagtaa
     7141 atgatggtta tgcattggga aattatggcc tatctccttt aaaatcaatc aattttcata
     7201 gagctaggtg gaaagaaatg gtaaaaccct attttgaaaa aaatgaaatt tttaaaatcc
     7261 aacaggatgt tattttctaa aataaatatg gtagataacc aatataaaaa gcatcaaaat
     7321 gaacaaggag gaatctgatg cttggagcaa ttattggaga tattgtcggt tctgtttacg
     7381 aatggaacaa tatcaaaaca aaggactttc ctttatttcg gaaggactgc ttttttacag
     7441 atgacacggt tatgacctgt gctgttgcag aagcaattat gaatggtgga caaaaagacg
     7501 acttcattga cgcgatgaag aaatatggca gaatgtatcc gaatgctgat tacggtgctc
     7561 ggtttaatgc atggctaaac agcgataacc gtgagcctta taatagcttt gggaatggat
     7621 cagctatgcg tatttctcca tgtgcttgga tcatggactg tggtttttat gcgaaaactg
     7681 gtatatggcc atcatctaga ggacttacga gtctttctgc agaggtaact cataatcatc
     7741 cagaaggtgt caaaggcgct atggctacag ctgatgctat ctttctatgt cgtttttact
     7801 ttggtggtta ttgtagagag tacgagcaat caattaacga caatcctaca gagtgtaaaa
     7861 gacgaattaa ggattatata gaaaaagaat acgattacaa tctatctcaa actttagatg
     7921 aaatccgtcc taactatcgt tttaacgaaa catgtcagga aactgtccct caagccatta
     7981 tcgcctttct tgaaagtaga gacttcgaag atgcgataag aaatgccatc tcacttggtg
     8041 gcgacagtga tactctcgca gcaatcactt gtagcatagc agaggcagct tacggtattc
     8101 ctgattggat caaggataag gcctattctt acttggatga acccttaaag gatgtagtta
     8161 ggcgatggga aaatagaata aaagcgtatt aatctccagt acgtcagatt tctcttttct
     8221 gtattttcat tgtataatag gattacattt acttgcatac gacgaaatgt aaacatttct
     8281 gtttaaaatt aaggataaaa tcaatgaaaa aagcaatggt aattatcaac cctacttctg
     8341 gtggcgagaa ggctttggat tacaaagaaa agctggagaa taaagcaaaa gaatactttg
     8401 aatatgttga aaccaaaatt accgaaaaag cgctggatgc aacacatttt gctgaagaag
     8461 cttctcgtga gcagtatgat gcagtggttg tgtttggtgg agatggaact gtcaatgaag
     8521 tcatttcagg tattgatgag agagactaca ttcctaagtt agggattatc ccaggcggta
     8581 cgggtaacct cattacaaaa cttttggaaa tcaatcaaga catcgatggc gcaattgacg
     8641 aactggattt tgatttaacc aataagattg atatcggtaa agcaaatgac aactattttg
     8701 gttatatctt tagtatcggt tctctgcctg aggcgattca caatgttgaa atagaggaca
     8761 aaacaaaatt cggtatttta acctatgctg taaataccat gaagtctgtc atgacagatc
     8821 aggtctttaa cattaaggtt gagacagaaa atggaaatta tgttggtgaa gctagccatg
     8881 ttttggtcct tttgacaaat tacttcgctg ataagaaaat ctttgaagaa aacaaggacg
     8941 gctatgccaa cattttgatt ctgaaagatg cctctatatt ctccaaatta tccgtcattc
     9001 ctgatttatt aaaaggggat gttgtcgcaa atgataatat cgagtatatc aaagcgcgta
     9061 atattaaaat ctcttcagat agtgaattgg agtcagatgt tgacggagat aaatcagata
     9121 acctacctgt agaaatcaaa gtcctagctc agcgagtaga agtattttca aaaccgaaag
     9181 aggattagta tatagagaaa gcctttttta aggctttttg tatactttaa aagatagttc
     9241 ctttaacaac ggacattcct tgcaaatagt ttacaaaaat agtatactgg atttattgag
     9301 tttgaaaacg tttgcgtaaa atttgaatga atactttagg agacaaattg atggaattga
     9361 gtgctattta ccataggcct gagtcggagt atgcctatct ttataaggat aagaaactcc
     9421 atattcgaat tcgaactaag aaaggggaca ttgaaagcat caacttgcac tatggggacc
     9481 cttttatctt tatggaggag ttttatcagg atacaaaaga aatggtcaag ataacttctg
     9541 gtaccttatt tgaccattgg caggttgaag tgtcagttga ctttgcacgt atccagtatc
     9601 tctttgagct cagagataca gaaggtcaaa atattttgta tggcgataaa gggtgtgtgg
     9661 aaaattctct agaaaatctt catgcaattg ggaatggatt taagttgcct tatcttcatg
     9721 agattgatgc ctgcaaggtt cctgactggg tttcaaatac ggtatggtat cagatatttc
     9781 ctgaaagatt tgccaatggc aatgctctat taaacccaga agggacttta gactgggatt
     9841 catctgtcac acctaagagc gatgatttct ttggtggtga tttacagggg attattgatc
     9901 atatggatta cttgcaagac ttgggtatta ctggactata tctttgtccc atctttgaat
     9961 ctacaagcaa tcacaagtac aatacgacag attactttga aattgaccgt cattttggag
    10021 acaaggagac ctttcgggaa ctggtggatc aagcgcatca tcgtggcatg aaagtcatgc
    10081 tggatgcggt atttaatcat attggttcgc aatctcttca atggaaaaat gtcgtcaaaa
    10141 atggtgaaca gtctgcttat aaggattggt tccatattca acaattccca gtgacaactg
    10201 aaaagctagt taataagaga gacttaccct atcatgtttt tggtttcgag gactatatgc
    10261 ctaagctaaa tacagccaat ccagaggtca agaattatct tttaaaggtt gcgacttatt
    10321 ggattgaaga gtttaatatc gatgcttggc gtttggatgt ggctaatgag attgaccatc
    10381 agttctggaa ggattttcgt aaggcagttt tagctaaaaa tcctgatctt ttcgagatta
    10441 taaaaaatat aaagaatcta gtcataaatt tgaattgaaa caacgtcttt attttttgct
    10501 tcagcaatct aaatcgtttg atgatttttt agagaaagca aagcagttgc atgttcagat
    10561 tgattttagt caaaagcata gccgtttttt gatgacagat agaacgatga taaaaccaat
    10621 tcgagggcgc caactcagca aacgagatct atatgatgaa gaatttttta gaacgcattt
    10681 tgctaagcaa gagattgaaa gtcgtttaga atttttgtta aaccgtgtca attctttaga
    10741 agatttaata acaaaagcaa aagaattgaa tctaaccatt gacttaaaac aaaaaatgta
    10801 acttttatcc tggaagaaaa taatcaaaag ataagtttgg gtcatcaaaa aataagtgat
    10861 aagaaattat atgatgtcaa attttttcaa gattatttta aaaataagga agtcgttgct
    10921 tcagaaggat tagagaattt acaggaacag taccatgctt tccaagaaga acgagataag
    10981 gataaagtat ccactgaaga gattgagaaa gcctttaaga catttaagga aaaatgagat
    11041 accgttcgtg aatttgaagt ggaacttgca gagaaccaaa tagagaagct agttgataag
    11101 ggcgtctata tcaaggtgtc tttcggtgtc aaacagagcg gtcttatttt cattcccaac
    11161 tatcaattgg atattatgga agaagaaaat cataaaaaat ataaagtcta cattcgagaa
    11221 acgtcttctt actttgtcta taataaagaa aacatggata ataattgttt catcaagggt
    11281 aggaccttaa tcagacaatt gagcaacgat agccaaaaac tcccctatag acgaccaact
    11341 ttaaaaagtc ttcaagagaa gatttctgaa attaatctta tgattgaact atctaacacg
    11401 aacaaacaat accaagaaat caaagatgag catgtattag aaattgcaga gattgatatg
    11461 aagctagaag aaacccaaga aaaaatcgcc accttaaaca agatggcgga agtccttatc
    11521 aatttgaaga gtgaagatca tgagactaga aaattagcta agtatgattt tgaccaaatg
    11581 aacatgacgg aatcaataat gttagatcga ctcaatacag atattttaaa attacaacag
    11641 gaacttggta atgaaattaa taaatatgag gagatagcta gaagattgga tttgtttgtg
    11701 aaaattatta ataccaataa atttacagtt ctaaaatttc acgagaatgc cttactagaa
    11761 taatattatt tacgactaat tagttaaaag atagagaatc atttcattta ttgtttacaa
    11821 gtttatcaaa atggctagta tagtgtaatt ttaacttgtc ttctcctaaa atatcgagaa
    11881 cttgtatagc ttgtttcatt gtttcaatac cactacttaa ttgacgttta aattcatagt
    11941 aaccggttgc atagagaaaa actgtctgtt cataaaagtt taattcattc tctaacaatc
    12001 cctttatctc attaattaaa taagagcaat tagaaaattc ttctttatct atgctgagaa
    12061 tgaaacaatt tatagctagc tgagtgacaa tccgcttatt tgttttattt agagatgagt
    12121 aaatataatt atttaacatt tctttagtta ataagaagta ggagttgtag ttaattgttc
    12181 gtacacagtt acctaataaa ataatctcat aataacccca tttttcaact ttaaagagat
    12241 aatctgctag ttgaagtaat tcatcatctg atggaatgat tcttgaatcc attgtgtgta
    12301 aaatggattt taccattgtt ttttcaaaag aatctaaagt gtaatttgag gaatccgaaa
    12361 gtagagattg tatattattg atgttttgta atgaatattg tttacggata tactgtatta
    12421 agttggcaaa tgactcagtt tttgtatagt cttcatcgtg taaaataaga aactcatcca
    12481 aagtaatgtg taatttgtct aaaatattga tcagtcggat acatgatatc tctgactctc
    12541 cacgttcaaa tcgggatatt tgcgattttg aaagatgctc atcagcaaca gagcatagac
    12601 tgatttgttt gcctttacga acttttctaa gtgtgatgcc aagttttgat ttcatagttt
    12661 ttcccattct cccaacaaaa agttaactta gttttattta ttgtacaata aataaaaatt
    12721 gaaaggaagt ctaaatatga agaaaatttc aaaatttttc ccaattttga tgctagtgat
    12781 ggacattatc attattgttg gtggttaaat cacttaggtg tacacctaag tctttagagt
    12841 atctaaagac tatacttact agctaaaaca tatttaagtt aaatcgtaaa attttagaga
    12901 gtggtgagac tttgaaacat aaaaaagtat taattatagg gtatggtata atgactcggg
    12961 gtatattaaa aatcctgaaa cagtcgaaaa aatataatat atacctatat agtaggcatc
    13021 taaattcaac aataaatgga ataatattta ttagagaaga tgaattacct gatgctataa
    13081 atcaggttga ttttataatc acttgtttta gtaatcatat tgaaacggat aatttcatta
    13141 atgagttttt attaaatata caatcacttc gtaaaaccat agtaattgat tttacaacct
    13201 ccaggattga ttgcgttgaa aaatttaaaa aaactgttga aattaaaggg ggatactata
    13261 tagaggctcc tttcacagga ggtaagttag gaagtaatag tggtcaacta tcaatttttt
    13321 tacatattga tgaaggtgta aactataata aaaaggagtt aatggaatta ttaaaattaa
    13381 tttcaaaaaa aatatacttt tttgaaaaga gtacggaacc aacaaaattc aagttaattt
    13441 ataactcgtg gggagcgtat ttgctttact ctattaagct attcaaccct ttacagtatg
    13501 atttttcacc aaagtctcta gaggtagcga atacaatcgt atgtaatgat ggttggatga
    13561 gtttagtatg caactccaaa ttagaacaga tcaatgatca agattttgat gacatacact
    13621 ttagagtaga atatatggta aaaaatttag aatatgctaa tttttcagtc tttcatgatg
    13681 aagtgaaaga aataaattat ttattacagc aatataggga ttgcttagta actgatagtg
    13741 gaaaagatta tacggtaata ggaaagtatg ataacttata ggaatgactt gctgtctaaa
    13801 gaattagata tactaatttc attttttaaa aaatgcgagg taggaaaaat ttcactcgtt
    13861 attactggtt ccttggcaag aggtaatcca agaatcaagg atgggaaatt agaatcggat
    13921 attgatattc tagttatagt agacagtatt cagcaattaa ttagtataaa aaagacttta
    13981 gagggaaggt ttcactttgt acataaaatt tctttgattt tttgtttgaa ggaaagaata
    14041 aatcgaagtc gttatcgtgg aattattaat agtattagaa gtgtagataa tcttttagta
    14101 gataatctgc atataaaaaa tcaaataata gaagctttag actcacctac caatattgtg
    14161 gagcagactc gctctatgat tcaggaattt tgttattatt catcaaaata tttaatttca
    14221 aagaataatt atttggaatt aaaactagaa aagtattgga aggagattgc aacattaaat
    14281 catatcgata aaaagataaa acacctagat tttgaaagaa tatttgctgt tttaaaagaa
    14341 cacaaaatac aaattttgga ttcaagtgaa tattttttcc aaaatgtaaa aacttctgag
    14401 aatatttatt tagagatgag ggatttagta tctttggaaa atcaaggatt agactttgaa
    14461 cattgtattt tgagcttggg ggaaagatga taataaatac attaggacca actgcaacag
    14521 attgtttttt atgcaataaa tcgtataaaa ttaaaagtag atgtgattgt actgtatgat
    14581 agttttgata gtatagttaa ttgctttgat aaattaaaag ggcaatatat attattatct
    14641 gtagctttcg agagtagtat taaaaattat agttggaaag atttcaactt tgaatatcat
    14701 aagcggattg aaattgtgga ttcttttcac tcttttacta agggaatggt tctaatcgag
    14761 aattgtaatt ataaaattaa tagggcgatt atccaacctg caactgagat tttgatgtta
    14821 aactatttaa agaaaaaaag tatggatctg aggatagatt ttacccatag taaagttatg
    14881 gcaaataaaa aatttctgga agaaggttat cgtttttcaa tagtaagtca agaaacgata
    14941 attaataatg atgatattat tatttgtgaa actttctctc cagaaatgat ttggtgctta
    15001 tatagagtga aaggatagaa aatgttttct gaaattatta agaaatatga tattgttaca
    15061 ctgaaagata gtggtttttt gagaggtgat tggttcatag gttcagcgtt aatggctcat
    15121 gactatgaaa gccttaagga agggatatat ttctatcccc aggaaacaat ttggacaaga
    15181 atcttggatt taga
//
LOCUS       DAVHSH010000042        15181 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000042 DAVHSH010000000
VERSION     DAVHSH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.042"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            30..239
                     /locus_tag="VVR08_001514"
     CDS             30..239
                     /locus_tag="VVR08_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075413.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            718..909
                     /locus_tag="VVR08_001515"
     CDS             718..909
                     /locus_tag="VVR08_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075414.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDF"
     gene            1023..1826
                     /locus_tag="VVR08_001516"
     CDS             1023..1826
                     /locus_tag="VVR08_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6075415.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(1883..3424)
                     /locus_tag="VVR08_001517"
     CDS             complement(1883..3424)
                     /locus_tag="VVR08_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6075416.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHDPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(3426..3908)
                     /locus_tag="VVR08_001518"
     CDS             complement(3426..3908)
                     /locus_tag="VVR08_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6075417.1"
                     /translation="MVKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            complement(3908..4993)
                     /gene="rlmN"
                     /locus_tag="VVR08_001519"
     CDS             complement(3908..4993)
                     /gene="rlmN"
                     /locus_tag="VVR08_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU6075418.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCSSGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(5014..5544)
                     /locus_tag="VVR08_001520"
     CDS             complement(5014..5544)
                     /locus_tag="VVR08_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU6075419.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(5701..6306)
                     /locus_tag="VVR08_001521"
     CDS             complement(5701..6306)
                     /locus_tag="VVR08_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU6075420.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(6479..7516)
                     /locus_tag="VVR08_001522"
     CDS             complement(6479..7516)
                     /locus_tag="VVR08_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6075421.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNVIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(7550..8485)
                     /locus_tag="VVR08_001523"
     CDS             complement(7550..8485)
                     /locus_tag="VVR08_001523"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU6075422.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(9038..10228)
                     /locus_tag="VVR08_001524"
     CDS             complement(9038..10228)
                     /locus_tag="VVR08_001524"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU6075423.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(10605..11948)
                     /locus_tag="VVR08_001525"
     CDS             complement(10605..11948)
                     /locus_tag="VVR08_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6075424.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(12088..12903)
                     /locus_tag="VVR08_001526"
     CDS             complement(12088..12903)
                     /locus_tag="VVR08_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6075425.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKENTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            complement(12955..15135)
                     /locus_tag="VVR08_001527"
     CDS             complement(12955..15135)
                     /locus_tag="VVR08_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6075426.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
BASE COUNT         4541 a         3306 c         2811 g         4523 t
ORIGIN      
        1 tgttagaata ggaaataaat gtttgaaaga tgctatccgt gaatactatt ttagaaaaat
       61 tttataaaga acaccaagtc aaacccttca tatcgcctga acgagatttg gatacttggc
      121 ttctaagtcc caagcccgtt cccaagcgaa atatggactt attagtagat gattcactag
      181 caggagatat cattttacta tggagaatcc agtttggtac ttttaccact gaaacatgat
      241 tttaaaaact cccattcgaa tatgattcaa aattcgctta gaatcaatgt tttcccactt
      301 tttcaaaaaa taaattttca tctaatttaa ataactttca attaagtgtg aattttgctt
      361 aaaatcatta aaaaacaccc catggtgtga accatgaagt gttgtaaatg ctgtgttgta
      421 gctagttctt agcgtttaga gaactggcta gctttacgag ctttcttaag atctggtttc
      481 caaaatactt tgagtacact tatggtattg atgcccctaa acatctaaaa actctggtag
      541 aaaaagggta tgctcttgtc gaaacttctt ttgactcact tgaccatcta aataatacca
      601 tgaaaaagaa tatcctgaag aagaagggag ttactggact ttctaaaatg aaatcttgcg
      661 acctggatca agcccttcat gagtattttt cagaagaaga attagctggt cactttcatg
      721 tccttctatg gactttttta caatggcatt gctatcacac ccaataccta tctaagcgcc
      781 tggttcgtaa actttattgc agctcttcct ctaaatttcc taattgttga accaattgcc
      841 cgttttatac taagttcttt tcagaaacca tttactgggg aagaagttga agaagttgaa
      901 gatttttaag atgatgatga aatcccaact attatctaag ccagttctgt aaactactaa
      961 tatttgaaat ccacttcctt ttagggtaca atggttataa atgaattttt gagaggaaca
     1021 gaatgaaaaa actagcaacc cttcttttac tgtctactgt agccctagct gggtgtagca
     1081 gcgtccaacg cagtctgcgt ggtgatgatt atgttgattc cagtcttgct gctgaagaaa
     1141 gttccaaagt agctgcccaa tctgccaagg agttaaacga tgctttaaca aacgaaaacg
     1201 ccaatttccc acaactatct aaggaagttg ctgaagatga agccgaagtg attctccaca
     1261 caagccaagg tgatattcgc attaaactct tccctaaact cgctcctcta gcggttgaaa
     1321 atttcctcac tcacgccaaa gaaggctact ataacggtat taccttccac cgtgtcatcg
     1381 atggctttat ggtccaaact ggagatccaa aaggggacgg tacaggtggt cagtccatct
     1441 ggcatgacaa ggataagact aaagacaaag gaactggttt caagaacgag attactcctt
     1501 atttgtataa catccgcggt gctcttgcta tggctaatac tggtcaacca aacaccaatg
     1561 gcagccagtt cttcatcaac caaaactcta cagatacctc ttctaaactc cctacaagca
     1621 agtatccaca gaaaattatc gaagcctaca aagaaggtgg aaaccctagt ctagatggca
     1681 aacatccagt ctttggtcaa gtgattggcg gtatggatgt tgtggataag attgctaaag
     1741 ccgaaaaaga tgaaaaagac aagccaacta ctgctatcac aatcgacagc atcgaagtgg
     1801 tgaaagacta cgattttaaa tcttaaaaac caaaagaaat acagtatcca cattcggtac
     1861 tgtatttctt ttactctcat tcttaagtta aattattaaa atcccatatt tggtctatcc
     1921 aaccttcata aaagtctgga tcgtggcaga ccataaggat agatcccctg tattctttga
     1981 gagcgcgttt gagctcatcc tttgcatcca catccaaatg gttggtcggc tcgtccagca
     2041 ctaaaacgtt gttttcacga ttcatcaaga gacagaaacg aaccttggct tgctctcccc
     2101 ctgataatac ttgaatctgg ctttcaatat gtttggttgt caaaccacaa cgggcaaggg
     2161 ctgcacggac ttctgcttga ttaagggcag gaaaggcatt ccagacagct tcaagaggag
     2221 tttggcgatt accgccttct acttcctgct caaaataacc aagttctaaa taatctccac
     2281 gctccacttc cccagcgatt ggcgagataa tgcccaagag actcttcaag agagttgttt
     2341 ttccaatacc attagcacca ataatcgcaa ccttttgatt gcgttcgaag gtaagattta
     2401 aaggcttagt aagaggacgg tcgtaaccaa tttgcaagtt cttggcttgg aagataaagc
     2461 gccctggtgt acgagctggt ttgaaatcaa aggatggttt tggtttctca ctttggagtt
     2521 cgataatatc catcttatcc aatttctttt gacgagacat agccatatta cgagttgcaa
     2581 cacgggcttt attacgagcc acaaagtcct tgaggtctgc aatctctttc tgctggcgtt
     2641 cgtaggctgc ctctagctga gatttcttca tagcataaac ttcttggaac tggtagtagt
     2701 caccagagta acgcgtcagc tgttgatttt ccacatgata gacaatatta ataacgtcat
     2761 tgaggaatgg aatatcgtgc gaaatgagaa caaaggcatt ctcatagttt tggagatagc
     2821 gcttgagcca atcaatatgc tcagcatcca agtagttggt cggctcgtcc aacagcaaaa
     2881 tatcaggctt ttcaaggaga agttttgcca aaagcacctt ggttctttgc ccacctgaca
     2941 aagaagttac atccgtatcc atgccaaagt ccataatacc aagagcacgc gctacttcgt
     3001 caatcttagc atccaaggta tagaaatcac gactctccag acggtcttga agttctccta
     3061 cttcttccat gagagcatca acatccgcgc cgtcttcagc cattttcata tagaggtcat
     3121 tgatacgagc ttcagctttg aaaagctcat caaaagccgt acggagaaca tcacgcaccg
     3181 actgtctttc agcaaggaca gagtgctgat ccaagtaacc agccgtcaca tatttggacc
     3241 actcaacctt tccttcatct ggcagcattt taccagtcac gatactcata aaggttgatt
     3301 ttccttcacc attggcaccg accaggccga tatgttctcc cttgaggaga cggaaggaca
     3361 catcttcaaa aattgcacgg tcaccaaaac cgtgactcag atttttaact tctaaaatac
     3421 tcattttaat tccttacctt gtttttatgt aatcgtttat aaaggagcca agccagatag
     3481 ccacccaaag tgttggtcca caaatcatca atctcaaaga cgcgattgaa atcaaagaaa
     3541 aagtccaaga ttaattgcgt acactcgatt ccaagactca caagaaaact aaaaagaagg
     3601 accttttttg ttttccgcaa atttggaaat agataaagga gttggaaaat cagaggaaaa
     3661 aacaagaaga cattgaggat attttgtaaa aaaatccaac ataattgtcc aatgtcactc
     3721 acttcgccca gtttccagag agaattgaaa ggagtcaaaa gaaaaaccag gcgtccaaga
     3781 tgctgaatac ctggagttcc cactcccacg gtagattgtt cttgaggagt aaagcaaaaa
     3841 cagacaatgc aaatgctata gaaaatgact ccccagacca aaatatgatt ataagtcttc
     3901 ttcaccatta aggatttacc gctgcgactg ccttctggcg gtcacgtttc attgtgttag
     3961 agcgcaattg tccacaagct gcgtcaatat ctgtaccatg ctcttgacga accacacagt
     4021 tgaccccttt tttcttaagc gtatcataga aagccaacac gcgctctttg ggactacggc
     4081 tatattggtc atgctcacta actgggttat aaggaatcaa gtttacataa gacaatttct
     4141 tgatgttctt gagcaattca gtcaattcca aggcttgttc tacaccgtcg ttgacttcat
     4201 taagcatgat atattcaaag gttacacgac ggtttgttgt ctcaatgtag tattcaatag
     4261 cagcaaagag tttttcaatc ggaaaggcac ggttaatctt catgatactt gaacgaagtt
     4321 cattgttagg tgcgtgaaga gacacggcaa gattgacctg aaccccttca tcagcaaagt
     4381 cacgaatttt atgagccaaa cctgaggttg aaaccgtgat gtgacgagca ccgatagcca
     4441 ttcctttatc atcattgata gtacgaaaga aattcaagac attgttgtaa ttatcaaagg
     4501 gctcaccgat tcccatgaca acgatatggc tgacgcgttc atcctgacca cgctcatcaa
     4561 agtatttctg aaccagcatg atttgcgcta cgatttcacc gttattgagg tcacgttgct
     4621 tcttaatcaa accagaggaa cagaaggtac aaccgatatt acagccgacc tgagtggtca
     4681 cacagacaga taaaccatag tgttgacaca tgagtacagt ctcaattaac ataccgtcag
     4741 gcaattcaaa gagatatttg actgtaccat cagcagactc ttgcacaata cgttgtttca
     4801 agggattgac cacaaactgg tcattgagct tagcaatcaa atccttggaa aggttggtca
     4861 tttcttcaaa tgactgcaca cgtttacggt agagccattc ccagatttga tctgcacgga
     4921 atttcttttc tccctgctcc aatacccatt cctgcatggt ttgatgtgcc aaactatgaa
     4981 ttgagggttt catttcttct ccttattctc tactcacttc tgacgaatga caaaatgacg
     5041 ttgttccttg tcctctttct gagaatgctg gtctttctga cgacgtctat ttttcttatc
     5101 tgcattcgac tttcgtttag tttgagtcgg tttctttcct tttctagaag gtgtttcttc
     5161 ttccgtctta cgcattttct tgtcaaatga tgctcgctta ggggcttcat tttctaagac
     5221 aaaataggca caaccataac tacaatactc taaaaggtag tcttgtaaac gactgatttt
     5281 ttcaagtttt tcttctgttc ggtcatcctt gtaaaaacct cgtaggcgaa gctgttcgtt
     5341 gctccagtcc cccacgatat aatcaaactt ggttaatact tctgaaaaac gctgattaaa
     5401 agtcgtcaca tcaaaggcat ccttgatatt ttcaaccaag gaaaaagcta tcccttccgt
     5461 ttcgaccttg tccccgtgta aatggaactc cggaccagga aacttgttat agttgtataa
     5521 ttcaggtgca atttcttttc gcatagatat cctttttcca cgattactta atactttatt
     5581 ctaccataat ttctagcagt tagcacgttt ctcataaaaa tgaaaaaagt ctgacgattt
     5641 tgtcagacca gaatcttata acctaaaaaa gagaagaaca attcttccct ccaactatca
     5701 ttatttagca gctgcgtaca attcatctac tttattccag ttgattactg aaaagaaagc
     5761 tttgatatag tcaggacgca cgttgcggta tttcacgtag taagcatgtt cccaaacgtc
     5821 caagcccaag attggttttt taccttctga gattggtgtg tcttggtttg ctgttgaagt
     5881 cacttcaagt ttcccttctt tgttgacaac caaccatgcc caacctgaac caaaacgagt
     5941 tgttgctgct gcagtgaagg ctgcttggaa ttcttcaaat gaaccaaatg ttgcatcgat
     6001 tgctgctgcc agttctgctg aaggagctgt tttctcggga gtcatcaatt cccagaaaag
     6061 agcgtggttc aagtgtccgc caccattgtt gataagtgct tgacggatat cagctggaat
     6121 agattctaca tcagcaagca aggcttcaag gtcttcaccg atttcagggt gtttttctaa
     6181 agctgcattg gcattgttga cataagtttg atggtgtttg tcatggtgca aatgcattgt
     6241 ttccgcatcg atgtatggtt ccaaagcgtc gtatgcatat ggaagttctg gtaagataat
     6301 agccatctgt aatacctctt tttctttcta tatgaaaatg ataacgcaaa cattcacttt
     6361 tttcaagttt tttgcttata gataaggaaa tcactgacat actttctaat aaaataagca
     6421 aatcagcaag aaacccacga caagataatc ctgacgcggg ttgtagtttc aacaaatgtc
     6481 aattgacctg actagcaatc tgtaagagtg ccttttcaaa aaggaaacct ttttcataaa
     6541 gacctgtctt aatctgatag tctgtctcaa tcaaatagga aatagcttgc ttcaaaaagc
     6601 tcaaagaaag tcctctcgaa tctcttaatg caaacttgat ttgataagga tttgggttac
     6661 gtcccagata actacctaaa ctacttgcaa tctgcgattc tgtttggcca gactccgcca
     6721 aaatcttcac ctgagtaaaa gtccgaaatt gtcccagcat gactgcaatc agcttgattt
     6781 catcttcccc ttgcaaggtc aagtctctca ccaaatcgcg cgcctgatcc atctttttag
     6841 ttagaataaa ctgagttaaa tcaaaaatat tgtcctgcaa ggtcttggga attacgttaa
     6901 caatatcctc ttcctcgata acagaatccg ccttatagga ctgtaaaaag agaagatttt
     6961 tctggatttc gctaaattga aaccccgact tgatgaggag attttcaaaa gaatgattgg
     7021 taaactgcag accttgtttc tgactccact tttggaaata ctggcgcaat tcttgttctt
     7081 ttacttctac tgcatcgaag accttggcat cacgcttaag taatttgact aaccgtcttt
     7141 tgctatccag ctttccttct gcaaagatta tcaacttagt tgttggagaa ggattgtcaa
     7201 ggtattcctc aaatgactta agctcatcat ctgtcaaaaa gcgtttctta gcagtcgtga
     7261 tatccataaa ataatctaat atcacgattt tctcatccgc aaagaaagga aggctgacca
     7321 actccaattc cacatccttg taaactactt ctttcatatc aaagtaggca aagttgaggt
     7381 cagcagaatc atacccaatc tgtttcaaca cttgactctt catcacttca aactgaccct
     7441 gatctgtccc tgtaaatagg ctcaggctcg gtaaatttga taaagtcaac ttctgacttt
     7501 cttcaatggc tagcatcgtc tctcctttct tctgattttt cgatttaatt tagtcaatat
     7561 agcgcaattt cccacggaaa tcttctaagc tctcgtagcc tttttccacc atgattgctt
     7621 tcagttcatt ggtaatgcgg tcaaaagcac tgacgccttc tttgtgaagg gtcgttccca
     7681 cctgcaccat acttgctcca cagaggatgt gttcaaaggc atctcgacca gtcagaacgc
     7741 cacctgttcc gataatttgg atttgaggat ttaaacgttg ataaaaggcg tgaacattgg
     7801 ctagagcagt cggtttgatg tattctccac caattccacc aaaaccattc ttaggccgaa
     7861 taacgacaga ttcgtcttct atatagaggc cgtttccgat agagttaacg cagttgacaa
     7921 acttgagcgg atatttgttg aaaatagctg ccgcttggtc aaagtgaaca atatcaaaat
     7981 aaggtggcaa tttaattcca agaggtttgg tgaagtaagc aaacacttct gccaaaatcc
     8041 ggtctgttgt ctcaaaatca taggcaatct gaggtttacc tggaacattt ggacaggaaa
     8101 gatttagctc agtcagacca cgaaaatcac tctcttggac ttttttcaaa atagtatggg
     8161 tttcctctgg agacatgccg accagagata agaagaaagt tcggttcgac tctttttcct
     8221 gcaaatctaa aagataatcc aaataatagt ctaagccatt atttggcaag cccatagagt
     8281 tgatggaacc aagtggaaca tcttggtagc gtggctcagg attcccctga cggaagtcca
     8341 aggtcgctgt cttagtaaca aaggttcctg ccgctgagtt tttgacctct tctaactcct
     8401 ctatcgtcat acaagccaca cctgctgcat tcatcaagca attgtcaaac tcaaaaccag
     8461 caatttgtgt tttcgttgat accatgattc taatcctcca gatttctttt attgctaata
     8521 ttataccata attttaattc taggtttact agattctgtg gttctatcta tttattcgga
     8581 aaagaaagtc tagtacagaa gtcatgctat ggaaacagct agtgtattgg aagtttgaac
     8641 aaggcttggg taacagactt ttgaatgaag tccaagcaac aaggagaaat ctcaaccatg
     8701 agtccattcc atgactctgt tgctctagaa aaccttgcaa tagtcaagtg ataacgaata
     8761 aaactttgga ttgaaatatc cccatgatta tctattacga ggagaaatct caacctttat
     8821 catttttaaa gaaatatagt aaaatgaaac aagaacagga gaaatcgatc aggacagtca
     8881 aatcgatttc taacaatgtt ttagaagttg aagtgtacta ttctagtttc aatctactat
     8941 acatgtaaat ctctactttc gcaaaatgga ttttcagaac agtatcccaa tatagttaaa
     9001 aactataaaa aagagaggac gttcccctct taaaatctta ttttactgct tctttcaaag
     9061 catctacctt atccaaacgt tcccatggaa gatcaatatc tgtacgtccc atgtgaccgt
     9121 aagccgatgt ttgacggtaa attggacgct taaggtccag catttggata atccctgcag
     9181 ggcgaaggtc aaagatttga cgagccgctt tttcaagttg actttcagct actgttcctg
     9241 taccgaaagt atcgatacga acagaaacag gttgcgcaac accgatagca taggccaact
     9301 gcacttctgc cttcttagca aggcctgctg caacgatatt cttggcaata tagcgagccg
     9361 cataagaggc tgaacgatcc accttagtcg catctttacc agagaaggca ccaccaccat
     9421 gacgagagta gccaccataa gtatctacaa taatcttacg accagtcaaa cctgagtccc
     9481 cttgaggacc accgattaca aaacgacctg tcggattgat aaagaatttt gtcttatcat
     9541 caagataaga agatggaata acttctttga tgaccttgtc aatcacatct tgatggattt
     9601 gttcattagt ggcctctgga tcatgctgag tagaaataac gactgtatct acacgtaccg
     9661 gacggtcatt ttcatcgtac tcaactgtaa cttgtgattt tgcatctgga cggagatagc
     9721 taatttctcc agacttacga agttctgcca gacgacgaac caatttatga ctgagtgcaa
     9781 ttggcaatgg cataagctct tctgtttcat ctactgcaaa tccaaacatg agcccttggt
     9841 cacctgctcc aatcaagtcc agtggatctt gatcagcatt tccacgaacc tccaaggctt
     9901 cgttaacacc ttgagcgatg tcaggagatt gttccaccaa agatgggtgt actcccaccg
     9961 tctcagcaga aaatccatat tctgtattgg tataaccaat ctctgcaatg gtatcacgaa
    10021 ccacacggtt aatatccaca taggcatttg tagaaatttc accaaaaacg tggacagaac
    10081 cagtatatac agctgtttca gcagcaacgt gcgcctctgg atcctttgct aaaatagcat
    10141 ccaaaatcgc atctgaaatt tggtctgcaa tcttatccgg atgcccctca gatacagatt
    10201 cagacgtgaa taatttacgt tctgacataa aaatgtcccc ccttaaaaaa tattgttata
    10261 gagttacaaa gtactgatag gaatttccat tatctaagag ttactagctt cagaaataaa
    10321 aacgatactt ttttatttct gaagctagta aggcgcatag ggtgaccgca gtatggcggc
    10381 aaccgtagaa agacgagcga cctcgaagcc gtcattcttt gcgaattgca aactactgat
    10441 aggaaaactc ttcgtaataa atacctacca tcttatcggg actatataac tttatcatta
    10501 taccattttt aatcgcaatt tgcagtcttt aatgtagtgt ttcggtttag atagttcgtt
    10561 ctcataaata aaaaagttgg agctcagtac tccaacaatt tctattaaaa tgtttggcgt
    10621 ttagctttac gctctgcacg accgcgagcg cgattttcag cacgcttagt tttacggcgc
    10681 ttttcatcaa ccgcccattg aattttcttc ttataacccg gtttgacttt tttctttttc
    10741 tttttaacca aaccaatcat ttcgatatca agtttatctt gttttttctc acggttggca
    10801 cgacgatcac ggtcataggt atcttgaaat tccccatctt tgaccatctt aggactaaac
    10861 ttgattccca atttctccaa ctcacggata tccgagtcat cacttggctg ataaagggta
    10921 atagctgtac ctggtaggcc atttcgtcca gtacgaccaa cacggtgaac aaaaaaagat
    10981 aagtcttgcg gaatggcatc attgatgaca tggctgacac cttcaatgtc aatcccacgc
    11041 gctgctaaat ctgttgcgac aatatactca aaatccagat tttgcacctg attcatgatt
    11101 cgcttgcgtt cacgaggggc aatatctcca tggatttttg caaccttcaa gccttgagca
    11161 gtcagatatg aatgcaattc atcagcacgc gttttagtgt taacaaaaat cattgccaaa
    11221 tacggctgca tcaactgagt caattggtaa atttgagcat tcttatcatg tcccttggtc
    11281 gaaatcaacc aattatcaat ggtgtcagaa ataaccgttt tagtcttaat tttctccata
    11341 acaggatttg ataagtattt tttcaagaat ggttgcagtt tttgtgggat agtcgctgag
    11401 aagaccatga attgcaagtc ttttggaaga ctgccagcaa tcttatcaac aatttccaag
    11461 aatcccatat ccaaggtcat atctgcttca tcaacaacaa atgtcttggc tttatgaata
    11521 gctaaatcac cagatttaac caagtcgtag atacggcctg gtgttccaat aacaatatga
    11581 ggctgattgc ttgccaattt ctcaatctgg cgagccttat ccgtaccacc cacataatta
    11641 accacacgaa cttcgacatc tgagtgagct gaaatctgac gcgctacttg gtaaatttga
    11701 gtagccaact cacgactcgg tgcagtaatc actgcttgta cactatcgct agcttcatct
    11761 aattgctgga aaatcggtaa caagaaagta tgagtcttac ctgaacctgt ttttgattct
    11821 cctactaggt cacgacctgc caaaacaata ggaatcaact tatcttgcac ctctgttgga
    11881 gttgtaaatt ttaactcctt caaggcttct ctaatatagt ttttaaattg aaatttcgta
    11941 aatgacataa catcctcgat tctatctatc ttatcaatta taccatattt tattccatta
    12001 cagtagtctc acttatttag gctatttcca gtagcttctc tagtaagaaa aggctagaat
    12061 tttatagttc caacctcttt tcagttatta tttccagttt aatatagcat tcaagccata
    12121 gtgatcactc acttgtggac tcttgttacc atcaaatacg acatgtaaat tttccaccgc
    12181 taactctttg gtagtaaaga cataatcgat tcgaaggggt tcagtgttct ctttccagcc
    12241 atcaatttca ggcggaacag tatagctacc acttttctct tgagcaactt caaatgcgtc
    12301 ttgtaagcct aatggactag ctaaaatagc ttggtaacct tcctgacctg ctgggttgtt
    12361 aaaatctcca gctagtaaaa gtggcttgtt caattttttc aagacagcct caaatcgtgc
    12421 ccattcttct tggaaacctt tatcccacca agagagatga acactggcaa ctgctagctc
    12481 cttgccatcg actacagttt cagctagggc aacacggcga gtatgatagt ctgttggatc
    12541 atccacatcc gaaaccaaaa tttctctggc ttcaataggt gttttagaca agatagccac
    12601 accttcatgg tagcggtcat agccgatatg gttataagcc caggtccagt agtaattttt
    12661 cccttgctct aacaactttt caaccaagag tctaacataa tggtcttggt gaataggctc
    12721 agctgctggc aaagcttgat aaaggtcatt aacctccacc tctgacgagg tcatctcctg
    12781 attgatttct tggaaacaaa tcaaatcata gtccttttca agaatatctt caagcaaaat
    12841 ctggaatttt tcctctgctt ctttctccat ccaactgtga gtattgagtg ttaaaaattt
    12901 cattcttttc tcccaaaata agaggttgga atacagcttc caacctcaag tatattacaa
    12961 ttctacttta gcaactgctg ttttagctgc aagagaacct gttttttcta atttaactga
    13021 tttaattgca tcaccatttg tgaagacaac tactgttgaa gtttcacgtc ctgctgcacg
    13081 gatagcatcc aagtcagctg tgacaaggag atctcctgct gcaacttttt gtccttcagc
    13141 aacatgaact gtaaatggtt taccttcaag acttactgtg tccaaaccaa tgtgaaccaa
    13201 tacttcaaga cctgcttccg tcacaatacc aaaagcatgt tttgttggga agatgcttga
    13261 tacagtacct gaaactggag atacaatgtt tccatttgca ggttctactg caaatccatc
    13321 acccatcatt ttttgagcaa atactggatc ctttacttgt tccaaagcaa caacttgacc
    13381 gtctgctact gagtaaactt cctcagtaag atctttgaag tgaacagtgt tttgttgtgc
    13441 ttcagtcatt tggcttggaa gagtttcagg aatgatttca cctgaatcaa ggatatcttg
    13501 gatatcagat ttcaaaatgt cagcttttgg accgtagata gcttgaaccc cttgtccttt
    13561 catcacaaga cccatagctc cttctgcttt ccattgctct gcatttccta ctttatctgc
    13621 atctttaaca gttacacgaa gacgagtcat acatgcatca acatcaacga tgtttacacg
    13681 tccaccaaga aggttgataa tgtttacagc ttgagagcct gctgcaactt tcacttcgct
    13741 gctggtttct tctgaacctt cagcagtttc gtagtttccg ttgcgccctg gagttgcgta
    13801 gttgaatttt tgaatcatga agtttgcgat aaagtacatg attacagcaa agagaacagt
    13861 tacccaaacg aagttaacga tatccatacc aataccagca ctgattgcaa taggtgtacg
    13921 agtcaagaac tcgattgaac cgaatgagtg catacgtagg tttacgacgt cagccatagc
    13981 gaaggcagca ccttgaacaa gtgagtaaac aagatacata ggtgttgcga tgaacatgaa
    14041 catgtattcg attggttcag taacccctgt caagaatgtt gcaagagctg ttgcaatcat
    14101 catacctttg tatttatgtt tcttgtcagc atcaacatta cggtagatag caacaatcac
    14161 acccatcaag ataccgaatg aaccgatcat ttgtccaact ttgaaacgag ctggatgtac
    14221 tgtatctaac aagtgttggt attgactagc atcagtacct ttaaggttta caaggtctgt
    14281 tacccatgca agccatagtg ggtcttgacc gaatacttga gtacctttag ctgcaccagt
    14341 taaaatgtca taagtaccac caagagctgt gtagttcatt gggatagtca acatgtggtg
    14401 aagaccaaat ggcaagagca aacgttccaa agtaccatac aagaatggtg caagaattgg
    14461 agcagtttct tgtgagttgg caatccagat accgaagtta ttgatacctg tttgaactac
    14521 tggccagaaa gcagcaagta gaattgcagc gattgctgaa cgaagaataa ctacaaatgg
    14581 tacgaaacgt ttcccgttga agaatgaaag tgcatcagga agtttacgga agttgtagta
    14641 tttgttgtaa gcagttgccc ctacaaaacc tgagataatc cctacgaata cccccatgtt
    14701 caaggctgga gcttcaagaa cactgataaa gtaatcagca actttgattg aaccaccaaa
    14761 gaaagtagtt accatagcat ctggattttt caacatatcg cctgacacac caaagattgt
    14821 accagtgata cggttaatca agataaaggc aagaccagcg gcgaaagcac caccagcacg
    14881 ttctttagcc cagcttcctc caatggctag ggcaaacaaa atgtgaaggt taccgataac
    14941 cccccaaccg atttgctcaa gaattccacc tgtgatgaca agtggtgtaa aggttgggtt
    15001 aatcatcacg atagacttac cgattgaaat catcaaacca gcagccggca taaccgcgat
    15061 aactaccatc aaagccttac cgaatttttg ccaaaattcg aaagacaaga catttttgaa
    15121 tgtatctttc atcattcaaa tctcctttat ttttatttag gcaaacgttt tacgaaaacg
    15181 t
//
LOCUS       DAVHSH010000043        15145 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000043 DAVHSH010000000
VERSION     DAVHSH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15145
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.043"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            54..1901
                     /gene="uvrC"
                     /locus_tag="VVR08_001528"
     CDS             54..1901
                     /gene="uvrC"
                     /locus_tag="VVR08_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU6075427.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            1891..2724
                     /locus_tag="VVR08_001529"
     CDS             1891..2724
                     /locus_tag="VVR08_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6075428.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKTQGASEYWLMGDIFLPGP
                     GANDLVALLKELPITASVRGNWDDCVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(2906..3706)
                     /locus_tag="VVR08_001530"
     CDS             complement(2906..3706)
                     /locus_tag="VVR08_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6075429.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            3877..4482
                     /locus_tag="VVR08_001531"
     CDS             3877..4482
                     /locus_tag="VVR08_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU6075430.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            4495..5895
                     /gene="pepV"
                     /locus_tag="VVR08_001532"
     CDS             4495..5895
                     /gene="pepV"
                     /locus_tag="VVR08_001532"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU6075431.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            5949..6527
                     /locus_tag="VVR08_001533"
     CDS             5949..6527
                     /locus_tag="VVR08_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU6075432.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFSLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            6687..6974
                     /locus_tag="VVR08_001534"
                     /pseudo
     CDS             6687..6974
                     /locus_tag="VVR08_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            7145..8470
                     /gene="brnQ"
                     /locus_tag="VVR08_001535"
     CDS             7145..8470
                     /gene="brnQ"
                     /locus_tag="VVR08_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU6075433.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            8568..9605
                     /locus_tag="VVR08_001536"
     CDS             8568..9605
                     /locus_tag="VVR08_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU6075434.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPSQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVVLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVMATERM
                     VDAYLKSALVD"
     gene            9607..10068
                     /locus_tag="VVR08_001537"
     CDS             9607..10068
                     /locus_tag="VVR08_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6075435.1"
                     /translation="MCLICQRIEWIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMETSVKLRFLEEMSLVQEAVAKTFKAEKMNIELLGNGDAHAHWHLFPRR
                     SGDMRGHGLNGRGPVWWVPWEEMAAEDCQVKSHELEQMIKALSDELEKYTV"
     gene            10094..10810
                     /locus_tag="VVR08_001538"
     CDS             10094..10810
                     /locus_tag="VVR08_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEU6075436.1"
                     /translation="MKKRYIVLSGLLAVTLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            11119..11544
                     /gene="rplK"
                     /locus_tag="VVR08_001539"
     CDS             11119..11544
                     /gene="rplK"
                     /locus_tag="VVR08_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU6075437.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            11752..12441
                     /gene="rplA"
                     /locus_tag="VVR08_001540"
     CDS             11752..12441
                     /gene="rplA"
                     /locus_tag="VVR08_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU6075438.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(12530..13836)
                     /locus_tag="VVR08_001541"
                     /pseudo
     CDS             complement(12530..13836)
                     /locus_tag="VVR08_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14132..14290
                     /locus_tag="VVR08_001542"
                     /pseudo
     CDS             14132..14290
                     /locus_tag="VVR08_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(14400..14546)
                     /locus_tag="VVR08_001543"
     CDS             complement(14400..14546)
                     /locus_tag="VVR08_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075439.1"
                     /translation="MKTKEQTRKLASGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FKEY"
     gene            14560..14922
                     /locus_tag="VVR08_001544"
     CDS             14560..14922
                     /locus_tag="VVR08_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU6075440.1"
                     /translation="MLEVGLNSLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSTVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT         4517 a         2908 c         3401 g         4319 t
ORIGIN      
        1 agactagtga gtagggtact atctttccct actttttttg ctataatgga actatgaaca
       61 acttgattaa atcaaaacta gagctcttgc cgaccagccc tggttgctac attcataagg
      121 ataaaaatgg caccattatc tatgtaggaa aggctaaaaa tctgcgtaat cgagtacggt
      181 cctattttcg tggaagtcat gataccaaga cagaggctct ggtgtctgaa attgtggatt
      241 ttgaatttat cgtcactgag tccaatattg aggcgcttct gctggaaatc aacctgatca
      301 aggaaaataa gcccaagtac aatatcatgc tcaaggatga taagtcttat ccttttatca
      361 aaatcaccaa tgagcgctat ccacggctta tcattactcg tcaggtcaaa aaggacggtg
      421 gtctttattt tggcccttat ccagatgtgg gggcagccaa tgaaatcaag cgacttctag
      481 ataggatttt cccttttcga aaatgtacca acccgccctc taaggtctgt ttttattacc
      541 atatcggcca gtgtatggcc cacaccatct gtaagaagga tgaggcttat ttcaagtcta
      601 tggcccagga ggtttctgat tttctgaaag ggcaggataa caaaatcatt gatgagctaa
      661 agggcaaaat ggcagcggca gcccagacta tggagtttga acgtgcggcg gaataccgtg
      721 acctgattca ggctattgga acgcttcgaa ccaagcaacg ggtcatggct aaggatctcc
      781 aaaatcgcga tgtctttggc tactatgtgg ataagggctg gatgtgtgtg caggttttct
      841 ttgttcgtca gggcaagctc atcgagcgcg atgtcaatct cttcccctac ttcaatgatc
      901 cagatgagga tttcttgacc tatgtgggac aattctatca agaaaaatct cacctagttc
      961 ccaatgaggt actgattccg caggatattg acgaagaggc tgtcaaggcc ttggtggatt
     1021 ccaagattct taagcctcaa cgtggagaga aaaagcagct ggtcaattta gctataaaaa
     1081 atgcccgtgt tagcctagag cagaagttca acctgctaga gaaatctgtc gagaagaccc
     1141 aaggagctat tgaaaatcta ggacgcttgc ttcaaatccc aaccccagtt cgcatcgagt
     1201 ccttcgataa ctccaacatc atgggaacta gtcctgtttc agccatggtg gtctttgtca
     1261 acggcaagcc tagtaagaag gattaccgta agtataaaat caagaccgta gtcgggccag
     1321 acgactatgc cagtatgcga gaggtcattc gcagacgcta tggtcgagta cagcgtgagg
     1381 ctttgactcc tccagatttg attgtgattg atggggggca aggtcaagtc aatattgcta
     1441 agcaagtcat ccaagaagaa ctgggcttgg atattccaat tgcaggtctg caaaagaatg
     1501 ataagcacca aacccatgaa ttgctctttg gagatccgct ggaagtggtg gacttgtctc
     1561 gcaattctca ggaatttttc ctcctccaac gcatccaaga tgaggtgcac cgctttgcca
     1621 tcaccttcca ccgccaactg cgctccaaaa attctttctc atctcaattg gatgggattg
     1681 atggtctggg acctaaacgc aagcaaaatc tcatgaggca cttcaagtct ctgaccaaaa
     1741 tcaaggaagc cagtgtggat gagattgtcg aagttggagt accaagagca gtagcagagg
     1801 ctgtgcaaac caagttgaac ccgcaggaaa cagaaatctt gcttcaagtg gcggaagaaa
     1861 gagtagatta ccaaacggaa ggaaaccaca ataaaccata aaatcgcaat tttatcagat
     1921 gttcatggca atgcgacggc gctagaagca gtgattgcag atgctaaaac tcaaggagcc
     1981 agtgaatatt ggctcatggg agacattttc ctccctggtc caggtgcaaa tgacttggtc
     2041 gctctgttaa aggaacttcc tatcacggca agtgttcgag gcaattggga tgattgtgtc
     2101 cttgaggctt tagatgggca atatggctta gaagacccac aggaagttca gctcttgcgt
     2161 atgacacagt atttgatgga gcgaatggat cctgcaacga ttgtctggct acgaagcttg
     2221 cctttgctgg aaaagaaaga aattgacgga ttgcgctttt ctatctctca taatttacct
     2281 gacaaaaact atggtggtga cttgctagtt gagaatgata cagagaaatt tgaccaactg
     2341 ctagatgcgg aaacggacgt ggcagtttat ggtcatgttc acaagcagtt gcttcgttat
     2401 ggaagtcaag ggcaacaaat catcaatcca gggtcgattg gcatgcccta ttttaattgg
     2461 gaggcgttaa aaaatcaccg tgcccagtat gccgtgatag aagttgaaga tggggaatta
     2521 ctcaatatcc aatttcgtaa agttgcttat gattacgaag ctgagttaga attggccaag
     2581 tccaaggggc ttccctttat cgaaatgtat gaagaactgc gtcgtgacga taactatcag
     2641 gggcacaatc tggaactatt agccagctta atagaaaagc atgggtatgt agaggatgtg
     2701 aagaattttt ttgatttttt gtaagagttt cctaaaatag ccaatgcaaa ctaaaaaagc
     2761 gattggctga tcccatcgct tttagtatat cttatactca atgaaaatca aagagcaaac
     2821 taggaagcta gccgtaggtt gctcaaagca cagctttgag gttgcagata aagctgacgt
     2881 ggtttgaaga gattttcgaa gagtgttatt gtaactgaga ttgatctggg aggtaagaac
     2941 cacctagata ggtattgctg agtttttcaa gggttccgtc ttgatagagt tctttgagcg
     3001 ctttatcaaa tttctcttta aactcttttt ggtcacttga gaaaacgata tagttgctgg
     3061 ggctatctgt agaaggtaaa tcaacgactg agaggtctaa accacggtcc ttgataatct
     3121 tttgaacgga taccttgtca aaaactagga aatcaaactc tccgttagca aggtctagga
     3181 ttcgtttacc aatatcctca ccagaaaaat caattgtagc gggattatca gtgtgtttct
     3241 gattccagtt attgatgaat tgagcgttag aagttccggt atcctcttgt gttgttttac
     3301 cagcgatctg gtcaagagaa gtcaaaggat ttttcttgtt gctgacaagg acgaggggat
     3361 tgttggaaat tggaagcgag taaaggtatt tttcagcacg ctcttttgtg taactcaaat
     3421 tattggccgc agcctgatag tgaccagaat caagtcctgg gaagatgctc tcccaggcgg
     3481 ttctttggaa ttgaatctcg tagtcgctga gtttttcatc tactgccttt aaaacttcga
     3541 tatcgaagcc tgtcagattg cccttgtctt cgtagtcaaa tggtggcacg tcgccagctg
     3601 tagcaaggac gattgtcttt tgagcgctag tctctttggg tgtagcttga ttcccacagg
     3661 caaccaaaaa tggtaggata gctagtaata ggctaaattt tttcatactg tctccattca
     3721 aatgtaaagt acttgctagt ttatcagaaa ctttcctgat aaaccaatat atatctttta
     3781 tgtctgtgat agaaaaactt aatcatgaaa aatccctgca agctctttca aattatggta
     3841 gaatggaagc agtagaatta gaaaaggaaa tcgattatga aatttcttga attaaataaa
     3901 aaacgtcatg cgaccaagca tttcactgat aagcctgttg atccaaaaga tgtgcgtacg
     3961 gctatcgaaa ttgcaacctt ggcgccaagc gcccacaaca gccagccttg gaaatttgta
     4021 gttgttcgtg agaaaaatgc tgaactggca aagttggctt atggttcaaa ctttgagcag
     4081 gtatcatcag cacctgtaac cattgcccta tttacagata cagaccttgc caaacgcgct
     4141 cgtaagattg cccgagttgg tggtgctaac aatttctcag aagaacaact tcaatacttc
     4201 atgaaaaatt tgccagctga atttgcacgc tacaatgaac aacaagtcag cgactaccta
     4261 gcactcaatg caggtttggt tgctatgaac ttggttctcg ctcttacaga ccaaggaatt
     4321 ggttccaata ttatccttgg ttttgacaaa tcaaaagtta atgaagtttt ggaaatcgaa
     4381 gaccgtttcc gcccagaact cttgatcaca gtgggttaca cagacgacaa attggaacca
     4441 agctaccgct tgccagtaga tgaaatcatc gaaaaaagat aggaagaaga aaaaatgata
     4501 gcaattgatt ttacagcaga agtagaaaaa cgcaaagaag acctcttggc tgacttgttt
     4561 agccttttgg aaatcaactc agaacgtgat gatagcaagg ctgatgccca acatccattt
     4621 ggacctggtc cagtaaaagc cttggaaaaa ttccttgaaa tcgcagaccg tgatggttat
     4681 ccaactaaaa atgttgataa ctatgcagga cattttgagt ttggtgatgg agaagaagtt
     4741 ctcggaatct ttgcccatat ggacgtggtt ccagctggta gcggttggga tacagatcct
     4801 tacacaccaa ctatcaaaga tggtcgcctt tatgcgcgcg gggcttcgga cgataagggt
     4861 cctacaacag cttgttacta tggtttgaaa atcatcaaag aattgggtct tccaacttct
     4921 aagaaagttc gcttcatcgt tggaacagac gaagaatcag gctgggcaga catggactac
     4981 tactttgagc acgtaggact tgccaaacca gatttcggtt tctcaccaga tgctgaattt
     5041 ccaatcatca atggtgaaaa aggaaatatc acggaatacc ttcactttgc aggagaaaat
     5101 acaggtgctg cccgtcttca cagctttaca ggtggtttac gtgaaaatat ggtaccagaa
     5161 tcagcaacag cagtcgtttc aggtgatttg gctgacttgc aagctaaact agatgccttt
     5221 gttgcagaac acaaacttag aggagaactc caagaagaag ctggcaaata caaggtgacg
     5281 atcattggta aatcagccca cggtgctatg cctgcttcag gtgtcaatgg cgcaacttac
     5341 cttgccctct tcctcagcca gtttggcttt gctggtccag ccaaagacta ccttgacatc
     5401 gcaggtaaaa ttctcttgaa cgatcatgag ggtgaaaatc tcaagattgc tcatgtggat
     5461 gaaaagatgg gtgctctttc tatgaatgcc ggcgtcttcc gcttcgatga aacaagtgct
     5521 gataatacca ttgcccttaa catccgctat ccaaaaggaa caagtccaga acaaatcaag
     5581 tcaatcctag aaaacttgcc agttgcttct gtcagtctat cagaacatgg tcatacccct
     5641 cactatgtgc caatggaaga tccacttgtg caaaccttgt tgaatgtcta tgaaaaacaa
     5701 acaggcctta aaggtcatga acaagtcatc ggtggtggaa cctttggtcg cttgttagag
     5761 cgcggagttg cctatggtgc tatgttccca gactcaattg ataccatgca ccaagccaat
     5821 gaatttattg ccttggacga tctcttccga gcagcagcaa tttatgccga agctatttac
     5881 gaattgatca aataaaacga tagaagtctg agatcttatg cttggacttc tttttggagg
     5941 gaaagtagat gtctcaaatc gaaagaatca aacaggctat catggcggat tcgcagaatg
     6001 ccagctatac agagcgtggc attgagcctc tctttgcagc gccaaaaact gctcgcatca
     6061 atatcatcgg tcaggctccg ggacttaaaa ctcaagaagc aggcctttac tggaaagata
     6121 aaagtggtga ccgcttgcgg gactggctag gtgtggatga agataccttt tacaattcag
     6181 gttattttgc tgttttgcct atggatttct actttccagg acatggcaag tcgggtgatc
     6241 ttccgcctcg tacaggtttt gcagaaaaat ggcatccgca gctcttacag gaattgcctg
     6301 atattcagtt aaccctcttg attgggcaat atgcccaagc ctactattta caggagaaaa
     6361 tcagtgggaa ggtaacggag agggtgaaac actataaaga ctatctgcca gcctattttt
     6421 cgctagttca cccatcacca cgaaatcaaa tctggatggc caaaaatcct tggtttgagg
     6481 cagaagtagt gccagatttg aaaaaaagaa ttaaaaccat tttatagtca atgaaaatca
     6541 aagagcaaac taggaagcta gtcgtaggct gctcaaagta cagctttgaa gttgcagata
     6601 aaactgacga agtcggtaac atacgcacgg taaggcgacg ctgacgtggt ttgaagagat
     6661 tttcgaagag tattagaaga aaaagaatga aagaaatagc ctttgacgca ttttaccagc
     6721 tttaccaaaa cgaccagctt tctctagtgg atgtgagaga agtggatgag tttgcagctc
     6781 ttcatttaga aggtgcccac aacctaccgc ttagtcaatt ggctgatagt tatgattaat
     6841 tggacaaaga tcgcttgcat tatattattt gcaaatctgg aatgagatcg gcgcgtgctt
     6901 accaattcct attagaacaa ggttataatg ttatcaatgt ccagggtggc atgttagcct
     6961 ttgaagaact ttaaaatttt gcatttctcc tacttggtgt ggactgggta ggagagtttt
     7021 atttttagat aattcttatt tttaagaaaa ttgaaaacat ttaatatttg cctcgtgatg
     7081 cttttttcag actcctaatc gtggtatact aggtcagtat tttataaata tgaaggagat
     7141 ttttatggct aaaaaaggta ccctaacagg tttgctcctg tttggaatat tttttggtgc
     7201 ggggaacttg atttttccgc cttctctagg tgctctatct ggagaacatt ttcttcctgc
     7261 catcgcaggt tttgtctttt caggcgttgg tatcgccgtc ttgaccctta ttattggaac
     7321 gctaaatcct aaaggatata tctacgagat ttcaacgaag atagcgcctt ggtttgcgac
     7381 tctttacctc tcagttcttt acttgtcaat cggtccattc tttgctaccc cacgtactgc
     7441 tacaacagct tacgaagtag ggattagccc ccttttgtcg gatgcaaata aaggacttgg
     7501 cttgattgta tttacggttc tgtattttgc ggcagcctat ttgatttcgc ttaatccatc
     7561 aaaaatctta gaccgcattg gacgtatttt aacgccagtc tttgcaattt tgattgttat
     7621 cttggtcgtt ctgggagcta tcaaatatgg tggaacaagt cctcaagctg cttcagctgc
     7681 ttatcaagct tctgcctttg gtacaggttt cctagaaggt tacaatactt tggacgccct
     7741 tgcctcagtg gcctttagcg taatcgcagt tcaaaccttg aaacaacttg gattttcaag
     7801 taagaaagaa tacatttcaa ctatttgggt tgttggtatc gttgttgccc ttgccttcag
     7861 cgctctttac atcggtttag gttttcttgg aaatcatttc ccagtaccag ctgaagcgat
     7921 gaagggtgga acaccaggtg tttacatctt gtcacaagcc actcaagaaa tctttggctc
     7981 aacagctcaa ctcttccttg cagctatggt taccgtaacc tgcttcacaa cgactgttgg
     8041 tttgattgtg tcaacagctg aattctttaa tgagcgcttc ccacaaatca gctacaaggt
     8101 ttatgcgaca gcctttacct tgattggatt tgctattgcc aatttgggtc ttgatgcgat
     8161 tatcaagtac tcaattccag tactggttat cttgtaccca atcacgattg ctatcgttat
     8221 gattgtcatt gtcaacaaat ttgttgccct ttcaaaacca ggtatgcagt tgacaattgc
     8281 tgtggttaca gttattgcca ttgcaagcgt actaggaagc tcgtttaagg ttgagtttct
     8341 tgcaaatctt gttagcgttc ttccttttgc caaggcatct ctcccatggt tggtgccagc
     8401 cattgttgga atcttgctct cattggttct accaaacaag caagaaagcg atgtttttga
     8461 aatggaataa tcacttaaat cacttttgta gccaagtcta caggagtgat tttctttttt
     8521 tatccgatga taaatgtgtt ataataggta gcgaaagagg tgaagaaatg aatcaaacag
     8581 tagaatatat caaagaactg acagccatcg catcgccaac gggcttcact cgtgaaattt
     8641 cgaattattt agtcaagact ctagaaggtt ttggttacca gccagttcgc acagctaagg
     8701 gtggtgtcaa tgtgaccatc aaaggtcaaa atgatgagca acatcgctat gtgactgccc
     8761 atgtggatac gctgggtgct attgttcgtg ctgtcaaacc agatggtcgt cttaaattgg
     8821 accgtatcgg tggttttcct tggaacatga ttgaaggtga aaactgtacc gttcatgtgg
     8881 ctagcacagg tcaaaaggta tcaggaacca tcctcatcca ccaaacttct tgccatgtct
     8941 acaaggatgc aggaactgca gaacgcacgc aggacaatat ggaagtgcgt ttggatgtaa
     9001 aagtaagcaa tgaaaaagaa actcgtgctc ttgggattga ggtcggtgat tttatcagct
     9061 tcgatccacg aactgtcgtg acagagactg gttttatcaa gtctcgccac ttggatgaca
     9121 aggtcagcgc agcaattttg ctcaatcttc ttcgtgttta taaggaagag gggattgaat
     9181 tgccagtaac aactcatttt gctttttcag tcttcgaaga ggtgggccac ggtgcaaact
     9241 ccaatattcc aagtcaggta gtagaatatc tggctgtaga tatgggagct atgggagatg
     9301 accagcagac ggatgagtat acagtgtcta tctgtgtcaa ggacgcttca ggtccctatc
     9361 actatgactt ccgtcaacac ttggtagttt tggcgaagga gcaagatatt ccatttaagc
     9421 tcgacattta tccattttac ggttcggatg cttcggcagc tatgtctgca ggagcagaag
     9481 taaagcatgc tctccttgga gctggtattg agtcaagtca ctcttacgaa cgaacacaca
     9541 ttgattcagt aatggcgact gagcgtatgg tcgatgctta tcttaagagt gcattggtag
     9601 actaatatgt gcttgatttg tcaaagaatt gaatggatca aggcagggga aaatccctac
     9661 tttgtaaaag aactagaaac aggctatgtt gttattggag accaccaata ctttaagggc
     9721 tataccttat ttctagcaaa agagcatgtc acagaactcc atcatatgga gacttctgta
     9781 aaacttcgtt ttctagagga aatgagtttg gtccaagaag ctgttgccaa aacgtttaaa
     9841 gctgaaaaga tgaacattga acttctagga aatggagatg cccacgctca ctggcatctc
     9901 tttccaagac ggtcaggtga tatgaggggt catggattga atggccgtgg tccagtctgg
     9961 tgggtgccct gggaagaaat ggcggcagaa gattgccaag tgaaatccca tgagttggaa
    10021 caaatgatta aagccttatc cgatgaatta gagaagtaca cggtctaaga gaggaagaat
    10081 agaggaagaa aaaatgaaaa aaagatacat cgttttatct ggtttgctgg cagtaaccct
    10141 agcagcttgt tcacaagaaa aagcaaaaaa tgaagatggc acagctaaga cagaacagac
    10201 agccaaagct gatgggacag tcggcagtaa gtctcaaggg gctgcccaga aaaaagcaga
    10261 agtggtcaat aaaggtgatt actacagcat ccaaggaaaa tacgacgaaa tcatcgtagc
    10321 caataaacat tatcctttgt cgaaagacta taatcccggg gaaaatccaa cagccaaggc
    10381 tgagttggtc aaactcatca aagcgatgca agaggcaggt ttccctatta gtgatcatta
    10441 cagtggtttt agaagttatg aaactcagac caagctctat caagattatg tcaaccaaga
    10501 tggaaaggca gcagctgacc gttactctgc ccgtcctggc tatagcgaac accagacagg
    10561 cttggccttt gatgtgattg ggactgatgg tgatttggtg acagaagaaa aagcagccca
    10621 atggctcttg gatcatgcag ctgattatgg ctttgttgtc cgttatctca aaggcaagga
    10681 aaaggaaaca ggctatatgg ctgaggaatg gcacctgcgt tatgtaggaa aagaagctaa
    10741 agaaattgct gcaagtggtc tcagtttgga agaatactat ggctttgaag gcggagacta
    10801 cgtcgattaa tactcttcga aaatctcttc aaaccacgtc agcgtcgtct tacctactga
    10861 ctgcgtcggt tctattcaca acctcaaaac agtgttttga gctgacttcg tcagttttat
    10921 ctgcaacctc aaagctgtac tttgagcagc ctgcggctag cttcctagtt tgctctttga
    10981 ttttcattga gtataaaaaa taaacttttc tcttgcaatt ccagataaat agtgtataat
    11041 gaatgggtat gcgaaaaaca tacttgtggg aggtaaaaat ctctaattac cgccaaaacc
    11101 acaaaggagg atttaaaaat ggctaaaaaa gtcgaaaaac ttgtaaaatt gcaaatccct
    11161 gctggtaaag ctacaccagc tccaccggtt ggacctgctc ttggtcaagc tggtatcaac
    11221 atcatgggat tcacaaaaga gttcaacgct cgtacagctg accaagctgg tatgatcatt
    11281 ccagttgtta tctcagttta cgaagataaa tcatttactt tcgttacgaa aacaccacca
    11341 gctgctgttc ttttgaaaaa agctgcaggt gttgaaaaag gatcaggtac acctaataaa
    11401 actaaagttg ctacagttac tcgtgcacaa gtacaagaaa ttgcagaaac taagatgcca
    11461 gatttgaacg cagcaaacgt agagtctgca atgcgtatga tcgaaggtac tgctcgttct
    11521 atgggattca ctgttgttga ctaatcaata acacagtaga aaatctcaca gcagtctatt
    11581 agttgctttt catactaggc aagtgactga ggcttgtact tgggtacagc aagggggctt
    11641 aaggccgtag gaagagaaaa atagtagact gaaaacccgc aagacttcat catttcgaga
    11701 agtgacgtgg gagatgaaaa tcgattgaac cacttacaag gagaatagaa aatggctaaa
    11761 aaaagcaaac aacttcgtgc tgctcttgag aaaatcgaca gcacaaaagc atacagcgta
    11821 gaagaagctg tagcacttgc aaaagaaact aactttgcaa aatttgacgc aactgtagaa
    11881 gttgcttaca acttgaacat cgacgttaaa aaagctgacc aacaaatccg tggagcaatg
    11941 gtattgccaa acggtactgg taaaacttca cgtgttcttg ttttcgcacg tggtgcaaaa
    12001 gctgaagaag caaaagctgc tggtgcagac tttgttggtg aagatgacct tgttgctaaa
    12061 atcaacgacg gttggttgga cttcgacgta gttatcgcta cacctgatat gatggctctt
    12121 gttggacgtc ttggacgtgt ccttggacca cgtaacttga tgccaaaccc taaaactggt
    12181 actgtaacaa tggatgttgc taaagcagtt gaagagtcta aaggtggtaa aatcacttac
    12241 cgtgctgacc gtgcaggtaa cgttcaagca atcatcggta aagtatcatt tgaagctgaa
    12301 aaattggttg aaaactttaa agctttcaac gaaacaatcc aaaaagcaaa accagctaca
    12361 gctaaaggaa cttacgtaac aaacttgact atcacaacta ctcaaggtgt tggtatcaaa
    12421 gttgatgtaa actcacttta atcagtagtt aaagtaatgt aaaaaagttg aagacgctat
    12481 gtctcaactt tttttggctc tttgtcaact gtagtgggtt gaaaaaaagc taagctcgag
    12541 aaaggacaaa ttttgtcctt tcttttttga tattcagagc gataaaaatc cgttttttga
    12601 agttttcaaa gtttcgaaaa ccaaaggcat tgcgcttgat aagtttgatg agattattgg
    12661 tcgcttccag tttggcatta gaatagtgta gttgaagggc gttgacaatc ttttctttat
    12721 ctttgaggaa ggttttaaag acagtctgaa aaataggatg agcctgctta agattgtcct
    12781 caataagtcc gaaaaatttc tctggttcct tattctggaa gtgaaaaagc aagagctgat
    12841 agagctgata gtggtgtttc aagtcttccg aatagctcaa aagcttgttt aaaatctctt
    12901 tattggttaa gtgcatacga aaagtaggac gataaaatcg cttatcactc agtttacggc
    12961 tatcctgttg aatgagtttc cagtagcgct taatagcctt gtattcatgg gattttcgat
    13021 gaaactgatt catgatttgg acacgcacac gactcatagc acggctaaga tgttgtacaa
    13081 tgtgaaagcg ttcaagaacg attttagcat tcgggagtga aacagtctgg gagactgttt
    13141 cagcctgagc ctagaaattt gaaagcgaag ctgtttagcc aagtcatagt aaaggctaaa
    13201 catatccata gtaatgattt tgacgcgaca tcggacagct ctatcgtagc gaagaaagtg
    13261 atttcggatg acagcttgtg ttctgccttt aagaatagtg ataatattaa gattatcaaa
    13321 atcttgcgca atgaagctca tctttccctt tgtaaaagca tactcatccc aagacataat
    13381 ctcaggaaga caagaaaaat catgtttaaa gtgaaaatca ttgagcttac gaataacagt
    13441 tgaagttgag atggaaagct gatgggcaat atcagtcata gaaatctttt caattaactt
    13501 ttgagcaatc ttttggttga tgatacgagg gatttggtga tttttcttta ccaggggagt
    13561 ctcagcaacc atcatttttg aacagtgata gcacttgaaa cggcgttttc taaggagaat
    13621 tctagtaggc ataccagtcg tttcaagata aggaatttta gaaggtcttt gaaagtcata
    13681 tttcttcaat tggtttccgc actcagggca agatggggcg tcgtagtcca gtttggcgat
    13741 gatttccttg tgtgtatcct tattgatgat gtctaaaatc tggatattag ggtctttaat
    13801 gtctagtaat tttgtgataa aatgtaattg ttccatatga atctttctaa tgagttgttt
    13861 tgtcgctttt cattataggt catatgggac tttttttcta cacaaaatag gctccataat
    13921 atctataggg gggttaccca ctacaaatat tatagagccc tttttttgat gtacgacggg
    13981 catgtcgtat atctgaggtg taagtcctca gtgggcacct gctaccggtg aacccaatag
    14041 cgattcccaa gtctgacgca ggaaataaga atcgtcagag gaagggatag cgaaatcgtg
    14101 gctctacgaa caggaacgtg ataataaggc ctatatagcg gataaggtat ctggctgggg
    14161 cgaccactat caattagtag ctcagaagtc ggtacttaaa cgtgctatat caaaaccagt
    14221 ccttgaaaaa cgtgaactgg tttcgtgttt ggattattac cttgaacgac atgcgttaaa
    14281 agttagttga actgccgtat gccgaacggc acgtacggtg gtgtgagagg ggctagagat
    14341 tatcccctac tcgatttcga aatctagtgg aatgaatctg gaatagtcca tcgagctttc
    14401 taatactctt tgaaaatctc ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta
    14461 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgaggctagt
    14521 ttcctagtct gctctttggt tttcattgag tataacacat tgttagaagt tggtttaaat
    14581 tccctaatca gtttgttcac atttaccttc gatatattat atcccatagt taaggttggt
    14641 catacagatg attatagcca tggagccgta aaacttagtg tttctttagt tgacaaagat
    14701 gccatgaaaa aaatatctgt aactgtaata ggatattttg aaataaatat agatgaaaat
    14761 atcaccgata ttctatacgt aaatggtact gctattcttt atccttattt acgttctatt
    14821 gtttcaacag tttcggcaat tgatagcagt gaagcaatgt tgctacctac cattaatgtt
    14881 ttagagttac tagataaatc tcaacctttt gaagaagaat aatttattag ctcactaaat
    14941 tgagggtaag gaaaagtaaa agcagtaaga aaaatgtctt gcattataca gcaacctttt
    15001 gggaatgagt agatggattg aataaaattt gattaagagt ggatgattta tctgtagatt
    15061 attattggac agttagtctt gaagtagtct aagaattagg ttataatcag tagaagcctt
    15121 gctaataatg aggaggttag tttat
//
LOCUS       DAVHSH010000044        14873 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000044 DAVHSH010000000
VERSION     DAVHSH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.044"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..301)
                     /locus_tag="VVR08_001545"
     CDS             complement(<1..301)
                     /locus_tag="VVR08_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075441.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIE"
     gene            1064..1378
                     /locus_tag="VVR08_001546"
     CDS             1064..1378
                     /locus_tag="VVR08_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6075442.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            1394..1780
                     /locus_tag="VVR08_001547"
     CDS             1394..1780
                     /locus_tag="VVR08_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6075443.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1809..3194
                     /locus_tag="VVR08_001548"
     CDS             1809..3194
                     /locus_tag="VVR08_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6075444.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            3197..3349
                     /locus_tag="VVR08_001549"
     CDS             3197..3349
                     /locus_tag="VVR08_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6075445.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            3372..4577
                     /locus_tag="VVR08_001550"
     CDS             3372..4577
                     /locus_tag="VVR08_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6075446.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4620..4841
                     /locus_tag="VVR08_001551"
     CDS             4620..4841
                     /locus_tag="VVR08_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075447.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4958..5455
                     /locus_tag="VVR08_001552"
     CDS             4958..5455
                     /locus_tag="VVR08_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6075448.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5430..5936
                     /locus_tag="VVR08_001553"
     CDS             5430..5936
                     /locus_tag="VVR08_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6075449.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5920..8367
                     /locus_tag="VVR08_001554"
     CDS             5920..8367
                     /locus_tag="VVR08_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6075450.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            8370..10547
                     /locus_tag="VVR08_001555"
     CDS             8370..10547
                     /locus_tag="VVR08_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6075451.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            10544..11545
                     /locus_tag="VVR08_001556"
     CDS             10544..11545
                     /locus_tag="VVR08_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6075452.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11542..12477
                     /locus_tag="VVR08_001557"
     CDS             11542..12477
                     /locus_tag="VVR08_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6075453.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12722..12838
                     /locus_tag="VVR08_001558"
     CDS             12722..12838
                     /locus_tag="VVR08_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6075454.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12854..14773
                     /gene="tet(M)"
                     /locus_tag="VVR08_001559"
     CDS             12854..14773
                     /gene="tet(M)"
                     /locus_tag="VVR08_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6075455.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLETYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         4817 a         2675 c         3115 g         4266 t
ORIGIN      
        1 gttcaatctc aattctataa atatattcca aattatcata atttctgtca tctaatagtc
       61 gagcagacaa ttgcttgaaa ttagagaggt tagatttaat ttcaatttgt tcattaaaaa
      121 aataatctaa tggtacttca agtcgttgtg agagtttgaa caaaaggtct gcggagggaa
      181 tgaaatgccc tctctcaatt ttactaatct gactttgttc acaaattcct tctgcaagag
      241 tttgttggga gagtctcaac tcttttcttt tcaatctgaa tttctctgcg agtgtattca
      301 ttaaagataa taaaccttcc tatttgctta atttcattat aaaattttta gttcaaaata
      361 gcaagttaaa agaataaata attctttata gtaataaaaa aaaaaaaagt tcaaaatgca
      421 ataaaaataa ttgactgaat aaactacata tgttagaata aaaacaagga aaaagaaagg
      481 ggtttcattg catgagaaaa aaacgtggaa ttaaaaaatt agttacattt gcatgactag
      541 gtgtttttat gtttagtaat acaattcctt accaacagtt tattcagaag aataaacaat
      601 tggagattcg agtgcaatca caaaaggagt ccaatggtct tgatgttggg aaggctgatt
      661 agttgattaa atgatgaaaa tactaattaa ctatatggta tttctgtttt atctaatttt
      721 taattagaaa aatagcataa aaatctagtt atccgcataa aaactggact tatcacactt
      781 tatcaaggtc aaaaccactc aatttactac taatttacta cttatgaatg agctttgata
      841 cgacgattta tccttgaaaa gtgaagatat aaagatactt ccaataaaat ttgaatattt
      901 aataggtaga cacttcaaaa aatgaggtgt ctattttttt acccgatttt gaaaggaagt
      961 gaacttatga aaacaaaaaa tcaagaatca aaaggtcgtt ccccactctt taagaccatc
     1021 aaacattcat tcagccaata aaaaagaaag gataggtaaa aatatggaac ttaaatttgt
     1081 gattcccaac atggaaaaaa cattcggcaa tttagaattt gctggcgagg ataaagtcgt
     1141 tcagcgaaga atcaacggac ggctaactgt cttatcaaga agctataatc tctattctga
     1201 tgttcaaaga gcagatgata ttgtggtggt gcttcctgct gaagctggcg aaaaacattt
     1261 cggctttgag gaacgtgtga agttagtcaa tccacgtatt accgcagagg gctacaaaat
     1321 cggcactcgt ggttttacaa attacctttt acatgctgac gacatgataa aagaataaag
     1381 aaagagagga aaaatgatga gattagcaaa tggcattgta ttagataaag acacgacttt
     1441 tggagaattg aaattctctg ctctacgtcg tgaagtgaga atccaaaatg aagacgggtc
     1501 ggtttcagat gaaatcaagg aacgtaccta tgacttaaaa tccaaaggac aaggacgcat
     1561 gattcaagta agtattcctg ccagcgtgcc tttgaaagag tttgattata acgcacgggt
     1621 ggaacttatc aatcccattg cggacaccgt tgctactgcc acctatcaag gagcagatgt
     1681 tgactggtat atcaaggcag acgatattgt gctgacaaag gattctagtt cattcaaagc
     1741 tcaaccacaa gcaaagaaag aaccgacaca agacaaatag tcgctaggta gaaaggagac
     1801 tttttcgcat gaaacagcgt ggtaaaagga ttcgcccatc tggtaaagat ttagtctttc
     1861 attttacgat agcgtcactc ctgcctgttt tcctgctggt tgtcggactg tttcatgtga
     1921 agacaatcca gcagatcaac tggcaggatt ttaacctatc acaagcagat aagattgaca
     1981 ttccctattt aattatcagt ttcagtgtcg caattcttat ctgcttgctg gtagcgtttg
     2041 tattcaaacg ggttcgctat gatacggtta aacaacttta ccaccgtcaa aaactggcaa
     2101 agatgatact tgaaaacaag tggtatgaat ctgaacaggt caaaacagag ggtttcttta
     2161 aagatagtgc tggtcgtaca aaggaaaaga taacctactt ccctaaaatg tattatcgac
     2221 ttaaaaatgg cttgatacag atacgggtgg aaatcacgct gggaaaatat caagaccaac
     2281 tcttacactt ggaaaagaaa ttagagagtg gcttgtactg tgagctgacg gataaagagt
     2341 taaaggattc ctatgtggaa tatactttgc tctatgacac catagccagt cgtatttcta
     2401 ttgatgaagt agaagctaaa gatggtaaac ttcgcttaat gaaaaacgta tggtgggaat
     2461 atgataagct ccctcatatg ttgattgctg gtggtacagg tggcggtaaa acttacttta
     2521 tactgacact gattgaagcc ttgcttcata cagattcaaa actgtatatt cttgacccga
     2581 aaaatgctga ccttgcggac ttaggttctg tgatggcaaa tgtctactat agaaaagaag
     2641 acttgctttc ttgcattgaa acattctatg aagaaatgat gaaacgtagt gaggaaatga
     2701 agcagatgaa gaactataag actggcaaaa attatgctta cttaggtctc ccggcacact
     2761 tcttaatctt tgatgaatac gtcgctttca tggaaatgct gggaacaaaa gaaaacaccg
     2821 cagttatgaa taagctgaaa cagattgtca tgttaggtcg tcaagctggc ttctttctaa
     2881 tactggcttg tcaacgtcca gacgcaaaat atttaggcga cggaatccgt gatcagttta
     2941 atttcagagt ggctttaggt cgtatgtctg aaatgggcta tggcatgatg tttggcagtg
     3001 acgtacaaaa ggatttcttc ttaaagcgaa tcaaaggtcg tggctatgtt gatgtaggaa
     3061 caagtgtcat atcagagttt tatactcccc ttgtaccaaa aggatatgat ttcttggagg
     3121 aaattaaaaa gttatccaac agcagacagt ccacgcaggc gacgtgcgaa gcggaagtcg
     3181 caggtgtgga ctgatcttgc tggctggtgt ggcaatagcc acgccagcac ttaacccccc
     3241 gtatctaaca ggggggtaca aatcgacagg aaacagtcaa aaaaacatta gaaaatcctt
     3301 tggttacaag ggatttacaa aatttcagcg tatgtcaaat gggctttaaa agttgacata
     3361 cgcctttttg attggaggga tttttactga atgaacaaac ttggttacag catttaaaag
     3421 aaaaacgctt ggcttatgga ctatctcaaa accgtttagc tgttgcgact ggtattacaa
     3481 ggcagtatct aagcgatatt gaaacaggaa aagtcaagcc atcagaggat ttacagcagt
     3541 ccctttggga agctctggaa cgcttcaatc ccgacgctcc ccttgaaatg ctgtttgatt
     3601 atgtaaggat tcgctttccg acaacagacg tacagcaggt ggtcgaaaac atcttacaac
     3661 tgaaactgtc ctattttctt catgaggact atggtttcta ttcttattca gagcattatg
     3721 ctttaggcga catattcgtc ctttgctccc atgaactgga caaaggagtt ctggtggaat
     3781 tgaaaggtcg tgggtgcaga caatttgaaa gctatcttct ggcacaacaa agaagctggt
     3841 atgagttctt tatggacgtt ttggtggctg gcggtgtgat gaaacgcctt gaccttgcca
     3901 ttaacgataa gacagggatt ttgaatatcc ctgtactcac tgaaaagtgc caacaggaag
     3961 aatgtatctc cgtcttccgc agttttaaaa gctatcgcag tggcgaactg gtacgcaaag
     4021 aggaaaagga atgtatggga aacaccctct atatcggttc attacaaagt gaagtttatt
     4081 tctgtatcta tgaaaaggac tacgagcagt acaagaaaaa tgatattccc attgaagacg
     4141 cagaagtaaa aaaccgtttt gagattcgat tgaaaaatga gcgtgcctat tatgcagtcc
     4201 gtgatttact cgtctatgac aatccagagc ataccgcctt taaaattatc aatcggtata
     4261 tccgttttgt agataaagac gattccaaac ctcgttctga ttggaaactg aatgaagaat
     4321 gggcttggtt tattgggaac aatcgtgaac gattaaaact aaccacaaaa ccagagcctt
     4381 actccttcca aaggacgctg aactggctat ctcatcaagt tgccccgacc ttaaaggttg
     4441 cgattaaact tgatgaaatc aaccagacgc aggttgtaaa agacattctc gaccatgcga
     4501 aactgacaga ccgacacaag cagattttga agcaacagtc agtaaaagaa caggacgtga
     4561 taacaacaaa aaaataactc aaatacaaat tcattgaata tagagaggag aacattttta
     4621 tgaattttgg acaaaacctt tataactggt ttctatcaaa cgctcaatca ctggtgcttt
     4681 tagcaatcgt tgtgattggc ttgtatcttg gcttcaagcg tgagtttagc aaactgattg
     4741 gctttttaat tattgcgatt attgcggttg gcttagtctt caacgctgct ggagtaaaag
     4801 acattttact agagctattc aatcgcatta ttggtgctta aataaaaccg ttcttttgtg
     4861 gaatataagt ggttttctta tgttccgcaa aggaatggta caccaaacga agtgcggtag
     4921 ggatttttga atctctacaa agaaaggacg tgaatatatg gacgatatgc aagtctatat
     4981 tgcgaattta ggcaaataca atgagggcga attggtcggt gcgtggttta cctttcccat
     5041 tgactttgag gaagtcaaag agaaaatcgg cttgaatgat gaatatgagg aatacgccat
     5101 tcatgactac gagttaccct ttacggttga cgaatacact tccattggcg aactcaatcg
     5161 actatgggaa atggtatcgg aattacccga agaattacaa tcggagctat ctgctctgct
     5221 cactcatttt tcaagcattg aagaactaag cgaacatcaa gaggatatta tcattcattc
     5281 cgattgtgat gatatgtatg acgtggcacg ctactacatt gaagaaacgg gtgctttagg
     5341 cgaagtacca gctagtcttc aaaactatat tgattatcaa gcctatggtc gggatttaga
     5401 cctttcagga acgtttatct caaccaatca tgggattttt gaaatcgtct attaaatctg
     5461 tcggtacatt actactggca gattttctat tttacggggt ggctcaatca gctaccccta
     5521 ttttttatga aaggattgat tacatgaaga aaatacgaag ctataccagt atctggtctg
     5581 tggaaaaggt actgtattct atcaatgatt ttagacttcc gtttcccata acctttacgc
     5641 aaatgacatg gtttgtcgtg tcactctttg cagtgatgat acttggcaac ttgccccctc
     5701 tttccatgat agagggagca tttctcaaat actttgggat tcctgtggct ttcacatggt
     5761 ttatgtctac aaaaactttt gatggtaaaa agccttatgg atttttgaag tctgtcattg
     5821 cttatgcact gcgaccaaag ctgacctatg caggaaaaaa agtaacgctt ggcagaaacc
     5881 agccacaaga agccattaca gcagttagga gtgaatttta tggcatatcc aattaaatac
     5941 attgaaaaca atctcgtctg gaataaagac ggggaatgtt atgcttacta tgagcttgtt
     6001 ccttacaatt actcatttct aagtccagaa cagaaaatac aagtgcatga ttctttcaga
     6061 cagcttatcg cacaaaatcg tgatggcaaa attcatgctt tacaaatcag tacagaatcc
     6121 agcatacgtt ctgcacaaga gcgttccaaa aatgaagtca ctggcaagct caaagcggtt
     6181 gcctatgaca aaatcgacca acagacagac gctttaatat ccatgattgg cgaaaatcaa
     6241 gtgaactacc gtttctttat cggctttaag ttgcttctca acgatcagga gttttctatg
     6301 aaaagtctta ccgttgaagc aaaaaatgct ttgtctgatt ttgtctatga tgtgaaccat
     6361 aagctgatgg gcgattttgt tagtatgagt aatgatgaaa tcctgcgttt tcagaagatg
     6421 gaaaagctct tagaaaataa aatctctcgt cgtttcaaaa tccgcaggtt agataaggac
     6481 gacttcggct atctgattga acacctttac ggacagacag gcactgccta tgaagagtat
     6541 gagtaccatc tatcaaagaa aaagctggat aatgaaacgc tgattaaata ctatgacttg
     6601 attaagccta ctcgctgttt ggtggaagaa aaacagcgat atttgaaaat ccagcaggaa
     6661 gatgaaaccg tctatgtagc ttactttacc attaacagca ttgtcggaga actggacttc
     6721 ccgtcctctg aaatcttcta ctaccagcaa cagcaattta cattcccgat tgatacgtca
     6781 atgaatgtgg aaattgtagc gaatcgtaaa gccctatcta ctgtccgcaa taaaaagaaa
     6841 gaactgaaag acttggataa ccacgcttgg caaagtgata atgaaaccag ctccaatgtg
     6901 gcggaagctc tggaaagtgt gaatgagctg gaaaccaatt tagaccaaag caaggaatct
     6961 atgtacaagc tgtcttatgt ggtaagggta tcagcaaatg atcttgacga actcaaacgt
     7021 cgttgtaatg aagtgaaaga tttttatgac gatttaagcg taaaactggt acgaccattt
     7081 ggggatatgc tcggcttaca tgaagaattt ttacctgcca gcaagcgtta tatgaatgat
     7141 tatattcaat acgtgacctc tgatttcctc gctggtttag gttttggtgc tactcaaatg
     7201 ctgggggaaa atgaggggat ttatgttggc tacagcttag atactggacg caatgtctat
     7261 ctgaaacctg ctcttgccag tcaaggggtt aagggttcag taaccaatgc gttagcgtcg
     7321 gcttttgttg gttcgctggg tggtggtaaa tcctttgcga ataaccttat cgtctattat
     7381 gcggtgcttt atggggcaca agcagtgatt gtagacccaa aagcagaacg tggcagatgg
     7441 aaagaaacct tgccagagat ttcccatgaa atcaatatcg tcactctgac ttctgatgag
     7501 aaaaacaaag gcttacttga cccttatgtg attatgaaaa atcccaaaga ttctgaatca
     7561 ctggctattg atattctgac attccttacg gggatttcct ctcgtgatgg ggaacgcttc
     7621 ccaatcctta gaaaagccat tcgtgcagta accaatagtg aagtacgagg gttgatgaaa
     7681 gtgattgagg aattacgggt tgagaatacg ccactaagta ccagtatagc cgaccatatc
     7741 gaaagtttta cagactatga ctttgcacat ttattattca gtaatggtta tgtggagcag
     7801 tctatcagct tagaaaaaca actgaacatt atacaggttg cggacttggt acttcccgac
     7861 aaggaaactt cctttgagga atataccact atggagcttt tatccgttgc tatgctgatt
     7921 gtcattagta cctttgcttt agactttatc catacagacc gaagcatttt caagattgta
     7981 gatttagacg aagcatggag ctttttacag gtagcacaag gaaaaacact atctatgaag
     8041 ctggttcggg ctggtcgtgc tatgaacgct ggggtatatt tcgtgaccca aaatacagac
     8101 gacctcttag atgaaaaact gaaaaataac ctcggcttaa aatttgcatt tcgttccact
     8161 gaccttaacg agattaaaaa gaccttagcc ttttttggtg tagacccaga ggacgaaaac
     8221 aatcagaagc gattgcgtga tttggaaaac gggcaatgcc ttatcagtga tttatatggt
     8281 cgtgtcggtg tgatacagtt ccaccctgta tttgaagaac tgctccatgc ctttgatacc
     8341 agaccacctg tgcgaaaaga ggtgtaaatg tgaaaccatc aatagtaaac agaataaaat
     8401 caaactggac gctgaaacgt ctaggtaaag tggcaatgac agtggctttc acacttgtga
     8461 ttgccatttt tcttttagcc atgctgggaa cggtggttca agctgcgggc ttggtagatg
     8521 atacggtcaa tgtggcaaat gaatacagcc gatacccact tgaaaactat caactggatt
     8581 tttatgtgga taatagctgg ggctggcttc cgtggaactg gtcggacggg attggaaaac
     8641 aggtcatgta tggactatat gccattacca attttatttg gacaatcagt ttgtatgttt
     8701 ccaatgcgac aggttactta gtacaggaag cctattcctt agacttcatt tccgctacag
     8761 cagattccat tggtaagaat atgcagacct tagctggtgt gagtgcaaac ggattttcaa
     8821 cagagggttt ctatgttgga ttcctcttac tcttgatttt ggttcttggg gtttatgttg
     8881 cctatacggg actgataaag agagaaacca caaaggcaat tcatgccatt atgaattttg
     8941 tgctggtgtt tatcctatcg gcttccttta ttgcctacgc tcccgactac attaaaaaaa
     9001 tcaatgactt ttcatcagac atcagtaatg ccagtttatc acttggcacg aagattgtca
     9061 tgccccattc cgatagtcaa ggcaaggaca gcgtggactt aatcagagat agcctgtttt
     9121 ccatacaggt tcagcaaccg tggctactgc ttcaatacaa cagttcagac attgaaagta
     9181 tcggtattga ccgtgtggaa agcctgctct ccaccagccc agattccaac aatggcgaag
     9241 acagagaaaa aattgttgcg gaagaaattg aagacagaag caataccaat ctaaccatta
     9301 caaagaccat taaccgttta ggtacagtct tcttcctatt tgtcttcaat attgggattt
     9361 ccatatttgt attcctatta acaggaatca tgattttctc gcaggtactt tttatcatct
     9421 atgctatgtt tctgcctgtg agctttattt taagcatgat tccatcattt gatggtatgt
     9481 caaaacgagc cataacaaag ctctttaata ccattttgac acgagctgga atcacattga
     9541 ttattacgac agcatttagt atttcaacca tgctctatac cttatcggct ggttatccgt
     9601 tctttttgat tgcttttcta cagattgtga cctttgcagg aatctacttc aagctgggcg
     9661 atttaatgag tatgttttct ctacagagta acgattctca aagtgtggga agtcgtgtga
     9721 tgagaaaacc tcgtatgctt atgcacgctc acatgcaccg tctacagcgg aaacttggac
     9781 gttccatgac tactctaggg gctgggtctg ccattgttac aggtaaaaaa ggacagtcgg
     9841 gttcggggag ttctgcaagg acacaagcag atcactcccg accagacgga aaggaaaaat
     9901 caacacttgg aaaacgtatc ggtcaaacca tcggtacagt agctgatacc aaagacagaa
     9961 tggtagacac tgctagtggt ttgaaagaac aggttaaaga tttgccgacc aatgcaagat
    10021 atgcagtata tcaaggaaaa tccaaagtaa aagagaatgt ccgtgattta accagtagta
    10081 tttctcaaac caaagcggac agagccagtg gacgcaagga acagcaggaa caaaggcgaa
    10141 aaaccattgc gaagcgtcgc tctgaaatgg aacaggtcaa acagaaaaaa cagcctgctt
    10201 cttctgttca tgaaagaccg actacaagac aagaacaata tcatgatgaa cagacctcaa
    10261 aacagtctaa tattcagact tcatataagg aatctcaaca agccaaacaa gagcgtccag
    10321 cagttaagtc cgatttttca agtccaaaag tggaacgcca aggcaatacc gttcaagaaa
    10381 aaaccgttca aaagccagca acttcaacca ctacagcaga tagaacttca caacgtccaa
    10441 tcacaaaaga acgtccgtct actgttcaaa gagtaccact acaaaataca agaagtagac
    10501 caccaatcaa aaccgccacc attaagaaag tcggtaagaa accatgaagt tgaaaacttt
    10561 agtgattggt ggttctggat tattcttgat ggtcttctca ctgcttctgt ttgttgccat
    10621 tttattttca gatgaacagg acagcggaat ttccaatatt cattatggag gtgtgaatgt
    10681 ttccgcagaa gtgctggctc ataagcctat ggtagaaaaa tatgccaaag aatatggcgt
    10741 tgaagaatat gtcaacatac ttcttgcgat tatacaggtg gaatcgggcg gtactgcgga
    10801 agatgttatg cagtcctcgg aatccctcgg tcttccacct aattcattga gtacagaaga
    10861 atccattaag caaggtgtga agtatttcag tgaattatta gccagtagcg aaaggctcag
    10921 tgtagattta gaatcggtta tccagtccta caattatggt ggtggtttct tagggtatgt
    10981 ggctaatcgt ggaaataaat atacctttga actggctcaa agtttctcaa aagagtattc
    11041 aggtggcgaa aaagtgtctt accccaatcc catagccata cctatcaatg ggggctggcg
    11101 atacaactat ggcaatatgt tttatgtgca actggtaacg cagtatcttg tcacaacaga
    11161 gtttgatgat gatacggtac aagccatcat ggacgaagca ctgaaatatg agggctggcg
    11221 atacgtttac ggtggagctt ccccgactac ttcttttgat tgtagcggac tgacacaatg
    11281 gacgtatgga aaagctggaa ttaacttacc acgaaccgca caacagcaat atgatgtgac
    11341 ccagcatatc ccactatcgg aagcacaagc tggcgatttg gttttctttc attctaccta
    11401 taacgctggc tcttatatta ctcatgttgg gatatacctt ggcaataacc gtatgtttca
    11461 tgcaggcgac ccaatcggtt atgccgactt aacaagcccc tactggcaac agcatttagt
    11521 gggagcagga cgaatcaaac aatgagaaag gaagatttaa tgatgaaatt tagaaaaaat
    11581 cagaataaag aaaaacagat accaaaggaa aagaaacctc gtgtctacta taaggtcaat
    11641 cctcataaaa aggttgtgat tgccttgtgg gtacttttag ggcttagttt cagctttgcg
    11701 atattcaagc actttacagc tatagatact catactattc acgaaacaac tatcatagaa
    11761 aaggaatacg ttgatactca tcatgtagaa aattttgtag agaactttgc gaaagtctac
    11821 tattcatggg agcaatccga taagtccatt gataatcgaa tggaaagtct aaaaggctat
    11881 ctgacagatg aacttcaagc tctcaatgtt gatacagtac gcaaagatat tcctgtatcg
    11941 tcttctgtaa gaggatttca gatatggacg gtagagccaa ctggcgacaa tgagtttaat
    12001 gtaacctaca gtgtagacca gctcattaca gagggagaaa atacaaagac cgtccactct
    12061 gcttatatag tgagtgtcta tgtagatggt tctggaaata tggtactggt taagaatccg
    12121 accattacca acatacctaa gaaatcaagt tataaaccaa aagccattga aagtgagggg
    12181 acggttgatt ccattacaac caatgaaatc aatgagtttt taacgacgtt cttcaagctc
    12241 tatcctacag cgacagccag tgaactttcc tactatgtga atgacgggat attaaaacca
    12301 atcggaaaag agtacatctt tcaagaactg gtaaatccta ttcacaatcg taaggataat
    12361 caagtcacgg tatcgctgac agtggagtat atcgaccagc agaccaaagc aacgcaggta
    12421 tctcaatttg atttggtact tgaaaagaac gggagtaatt ggaagattat agaataacaa
    12481 atattggtac attattacag ctattttgta atcacgtact ctctttgata aaaaattgga
    12541 gattccttga caaatatgct cttacgtgct attatttaag tatctattta aaaggagtta
    12601 ataaatatgc ggcaaggtat tcttaaataa actgtcaatt tgatagtggg aacaaataat
    12661 tggatgtcct tttttaggag ggcttagttt tttgtaccca gtttaagaat acctttatca
    12721 tgtgattcta aagtatccgg agaatatctg tatgctttgt atgcctatgg ttatgcataa
    12781 aaatcccagt gataaaagta tttatcactg ggatttttat gcccttttgg gtttttgaat
    12841 ggaggaaaat cacatgaaaa ttattaatat tggagtttta gctcatgttg atgcaggaaa
    12901 aactacctta acagaaagct tattatataa cagtggagcg attacagaat taggaagcgt
    12961 ggacaaaggt acaacgagga cggataatac gcttttagaa cgtcagagag gaattacaat
    13021 tcagacagga ataacctctt ttcagtggga aaatacgaag gtgaacatca tagacacgcc
    13081 aggacatatg gatttcttag cagaagtata tcgttcatta tcagttttag atggggcaat
    13141 tctactgatt tctgcaaaag atggcgtaca agcacaaact cgtatattat ttcatgcact
    13201 taggaaaatg gggattccca caatcttttt tatcaataag attgaccaaa atggaattga
    13261 tttatcaacg gtttatcagg atattaaaga gaaactttct gccgaaattg taatcaaaca
    13321 gaaggtagaa ctgtatccta atatgtgtgt gacgaacttt accgaatctg aacaatggga
    13381 tacggtaata gagggaaacg atgacctttt agagaaatat atgtccggta aatcattaga
    13441 agcattggaa ctcgaacaag aggaaagcat aagatttcag aattgttctc tgttccctgt
    13501 ttatcacgga agtgcaaaaa acaatatagg gattgataac cttatagaag tgattacgaa
    13561 taaattttat tcatcaacac atcgaggtca gtctgaactt tgcggaaaag ttttcaaaat
    13621 tgagtattcg gaaaaaagac agcgtcttgc atatatacgt ctttatagtg gcgtactgca
    13681 tttgcgagat tcggttagaa tatcggaaaa ggaaaaaata aaaattacag aaatgtatac
    13741 ttcaataaat ggtgaattat gtaaaattga taaggcttat tccggggaaa ttgttatttt
    13801 gcagaatgag tttttgaagt taaatagtgt tcttggagat acaaagctat tgccacagag
    13861 agagagaatt gaaaatcccc tccctctgct gcaaacgact gttgaaccga gcaaacctca
    13921 acaaagggaa atgttacttg atgcactttt agaaatctcc gacagtgacc cgcttctgcg
    13981 atattatgtg gattctgcga cacatgaaat catactttct ttcttaggga aagtacaaat
    14041 ggaagtgact tgtgctctgc tgcaagaaaa gtatcatgtg gagatagaaa taaaagagcc
    14101 tacagtcatt tatatggaaa gaccgttaaa aaaagcagag tataccattc acatcgaagt
    14161 tccaccgaat cctttctggg cttccattgg tctatctgta gcacagcttc cattagggag
    14221 cggagtacag tatgagagct cggtttctct tggatactta aatcaatcgt ttcaaaatgc
    14281 agttatggag gggatacgct atggctgtga acaaggattg tatggttgga atgtgacgga
    14341 ctgtaaaatc tgttttaagt atggcttata ctatagccct gttagtaccc cagcagattt
    14401 tcggatgctt gctcctattg tattggaaca agtcttaaaa aaagctggaa cagaattgtt
    14461 agagacatat cttagtttta aaatttatgc gccacaggaa tatctttcac gagcatacaa
    14521 cgatgctcct aaatattgtg cgaacatcgt agacactcaa ttgaaaaata atgaggtcat
    14581 tcttagtgga gaaatccctg ctcggtgtat tcaagaatat cgtagtgatt taactttctt
    14641 tacaaatgga cgtagtgttt gtttaacaga gttaaaaggg taccatgtta ctaccggtga
    14701 acctgtttgc cagccccgtc gtccaaatag tcggatagat aaagtacgat atatgttcaa
    14761 taaaataact tagtgtattt tatgttgtta tataaatatg gtttcttgtt aaataagatg
    14821 aaatattctt taataaagat ttgaattaaa gtgtaaagga ggagatagtt att
//
LOCUS       DAVHSH010000045        14256 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000045 DAVHSH010000000
VERSION     DAVHSH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.045"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            222..1667
                     /gene="cps4A"
                     /locus_tag="VVR08_001560"
     CDS             222..1667
                     /gene="cps4A"
                     /locus_tag="VVR08_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU6075456.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1669..2400
                     /locus_tag="VVR08_001561"
     CDS             1669..2400
                     /locus_tag="VVR08_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEU6075457.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLIESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2409..3101
                     /gene="cpsC"
                     /locus_tag="VVR08_001562"
     CDS             2409..3101
                     /gene="cpsC"
                     /locus_tag="VVR08_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU6075458.1"
                     /translation="MKEQNTLEIDVSQLSRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRDQGEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVSGTSVIVFLLEFLNTRVKRPEDIENTLQMT
                     LLGVVPNLSKLK"
     gene            3111..3794
                     /gene="cps4D"
                     /locus_tag="VVR08_001563"
     CDS             3111..3794
                     /gene="cps4D"
                     /locus_tag="VVR08_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4D"
                     /protein_id="HEU6075459.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SYGLCDTNIENLFVVQSGSVSPNPIALLQSKNFNDMIETLRKYFDYIIVDTPPVGIVI
                     DAVIITQKCDASILVTATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     ASYGNYGKK"
     gene            3810..5177
                     /locus_tag="VVR08_001564"
     CDS             3810..5177
                     /locus_tag="VVR08_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6075460.1"
                     /translation="MDKKGLEIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNKFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNPKNSKKILLLTVTENIEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVDLPGESYDIGEIISKFETMG
                     IDVTVNLNAFNKNLGRNKQIHEIVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     RGGMFKMDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RNGAK"
     gene            5181..5630
                     /locus_tag="VVR08_001565"
     CDS             5181..5630
                     /locus_tag="VVR08_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--LPS N-acetylglucosamine
                     transferase"
                     /protein_id="HEU6075461.1"
                     /translation="MKVCLVGSSGGHLTHLYLLKPFWKDRERFWVTFDKEDARSILEN
                     EIFYPCYYPTNRNLKNLIKNTILAFKILRKERPDIIVSSGAAVAVPFFYLGKIFGAKT
                     VYIEVFDRIDAPTMTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            5630..6133
                     /locus_tag="VVR08_001566"
     CDS             5630..6133
                     /locus_tag="VVR08_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug MFS transporter"
                     /protein_id="HEU6075462.1"
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGEGFIQDDVFIQTGYSNYVP
                     KFCKWEKLISYEKMNQLIKESDIIITHGGPATFMAVIAKGKNPIIVPRLKKFGEHVND
                     HQMQFVKITKEIYNLIVIDDISDLHLILHNFKDKHFETYLNNERFNVRFNVEISNLFK
                     GNKINEN"
     gene            6123..7295
                     /locus_tag="VVR08_001567"
     CDS             6123..7295
                     /locus_tag="VVR08_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU6075463.1"
                     /translation="MKIRIEPQYFLYKYLWFIILLPKQFMQLILFFLIALTLLPTYIK
                     EKQVFKIDTPSFCMVLWTIIYSISIIFNSLIDGLAVQVIFSDLSKAFNWLIAVFFYNY
                     YLKMPINIDRIKRYMYYNFTILVVFVGLFYIQRGSNVILFGRSLLDWDGFTLATSYGV
                     RYTGFLEYATLNGQLILFLLPLIRLFRFRFFTQTIIFAFLLEVLVLSKSRIAIVAMLI
                     YIAFAVVNEINSNNKWLIGIFCPIIPFMLFYNFEKIKQIFFQMFSSRSGSNATRFRVY
                     EESLKAINGMEMLLGAGVRIPSTVDILLGSHSMYISFIYRTGVLGSIIITVMFYYLFS
                     KFLKCDSSERLRSIGYILALSVFWLFEELDPHYWCLILFFSTISIFINNRKEEIVG"
     gene            7292..8311
                     /locus_tag="VVR08_001568"
     CDS             7292..8311
                     /locus_tag="VVR08_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6075464.1"
                     /translation="MIEVSIIIPIYNAEKTIKNCVDSALKQNLESLEVILVNDGSNDS
                     TSKILEQYGDNPQVMIFHQVNMGVSAARNVGLSYASGEYVFFLDSDDILDEGMLSKMY
                     QFAKSNKIDLLSCWHKEPSTTQYGGNDNSSASFIARTKEEIGNHFVDIFPRSACAKLF
                     LRRRIEENNIAFSTEMSLGEDMSFVCQYLMVSRSIAVIDGLYYTIQNVNPQSLSKRYV
                     SNIENSLLMQNQLWDQLLEVYPKIEENYYKQHMDFRFYLASLYVNNLFKFDSPYSSKE
                     KWDNIAQQLKKYRPFLDEKVSKEKKPKNMNEMVIFYLLKSKIPALIYSFYSFKEWWKK
                     KRLKN"
     gene            8326..9282
                     /locus_tag="VVR08_001569"
     CDS             8326..9282
                     /locus_tag="VVR08_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6075465.1"
                     /translation="MEDLVSIVVPVYNVEKYLKKSIESILNQTYDNLEVLLVDDGSTD
                     SSGEICDSFIKVDSRIRVFHKENGGLSDARNFGIEHMKGQYVSFIDSDDYISKDYVWK
                     LYSSIKNNDSEVSICSFSLVDETGEKIKDELLDSGEVSLSGQQILEKALTADGYRYVV
                     AWNKLYRSTLFEKLKFKKGMLYEDEFLNYPLFWDCKRVSIVEEPLYLYVQRKGSIIQS
                     NMTLEKIKMKDKMHTSRIEFYAEKKNSFLHQRSCQQYCNWIVTITVSHYNVLNVAFLK
                     YLQHQFRRIVKYTQNDDKKLIIQNILGYINIRLAAYVKSKVM"
     gene            9299..10218
                     /locus_tag="VVR08_001570"
                     /pseudo
     CDS             9299..10218
                     /locus_tag="VVR08_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729798.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
     gene            10211..11674
                     /locus_tag="VVR08_001571"
     CDS             10211..11674
                     /locus_tag="VVR08_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEU6075466.1"
                     /translation="MSNKISKNLAYNIGYQLIGIAFPLITSPYLSRILGAENLGIHSF
                     TISVALYFMMFMLLGIANYGNRTIATVKREGKEILSKTFWNIYYVQLLMSVLVTIAYL
                     IYLYFWVSSYKFIAILQLFLLLSNAVDITWLFYGLEDFKQIVFRNTLVKLLGLFLIFS
                     FVHESSDLWKYTLINGGVTLVGQLLLWGQLKGRLSWVKIQKKDLLSHIKPILVLFIPV
                     LAISIFSNMDKYMLGLMVGVKQVGFYDNANRIIDIPKALIAALEAVMLPRTSYLLAEG
                     QEEKSNYYIEVTILYAMMISSVLIFGIISVSDIFSLVFWGEEFLESGRLIAAMAPVFV
                     FSVPGNIIRTQYLIPRAKDKDYVLSLIIGALVNILLNCFLIKPFGAMGATISTVLAEF
                     VLYGVQFWTVRRDLDFKKYLKNGFIFYLFGMIMYLAIIAVKAHLQYNIINLILLIVLG
                     GIVYTGFCCFYILISRNVHFEILREKIKRKIGYENIL"
     gene            11712..11963
                     /locus_tag="VVR08_001572"
                     /pseudo
     CDS             11712..11963
                     /locus_tag="VVR08_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834986.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
     gene            11952..12320
                     /locus_tag="VVR08_001573"
                     /pseudo
     CDS             11952..12320
                     /locus_tag="VVR08_001573"
                     /inference="COORDINATES: protein motif:HMM:NF016357.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
     gene            complement(12598..12765)
                     /locus_tag="VVR08_001574"
                     /pseudo
     CDS             complement(12598..12765)
                     /locus_tag="VVR08_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12863..>14256
                     /locus_tag="VVR08_001575"
     CDS             12863..>14256
                     /locus_tag="VVR08_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEU6075467.1"
                     /translation="MTNFVKFRKNNLTRRKGILSFVVAFTLLLTYLLTYLLTASRPVF
                     AGGFPNDAKGISGNGKYYSLGQIEKLYSNQFATYNNLTVITSDTHENSDNFAFCLANG
                     KRFPSFTDEKPKGIYTLVKDINKEQYTKLLKENHKWSSIPNLNQAWDTFSRLSYMYLK
                     DPTDIVKRAWGTDLNTARTYFHQVIQYEIWRYTDGMRVSSDTNIYIYEKFSPQQKKAL
                     EMIRTDLYNFTVPYENLEYRFYKPDWVFGLGFQALATVRWKIEPATITVTKKWENVKE
                     GAEKPEVWIQLLKDDKPEGDRKRIEPDKGRTTFEIPNKDEINKYSVKEVDKEGRDWKH
                     KDFTAGQPVNKGNGHFEITNTKKEKPKIKVTFKKIAGDTNKDLAGAHLVLKKIFDDGN
                     GLLIKQWDTIGQPVDIDLDAGSYTLTEEKAPDGYMLAAPVSFYVEEDGQIILPKGEDL
                     EAQNDKTITMVDEK"
BASE COUNT         4859 a         1923 c         2735 g         4739 t
ORIGIN      
        1 ttagattgaa actagaatag tacacatctg cttctaaaac attgttagaa aacgatttga
       61 ctgtcctgaa caatttgtca tgttcttgtt tcattttact atatttttgg ttcgcgggaa
      121 gtctactaag atacttaaag atgcagatag tgaaaaaagg tgtagacatt accgtaaaaa
      181 agtgatataa tcgtatgatg ttcaaggtat aggtgttaat catgagtaga cgttttaaaa
      241 aatcacgttc acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat
      301 tgttagtttg ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc
      361 ttaacctagt ggtaactgcg ttagtcctac tagttgcctt ggtagggcta ctcttgatta
      421 tctataaaaa agctgaaaag tttactattt ttctgttggt gttctctatc cttgtcagct
      481 ctgtgtcgct ttttgcagta cagcagtttg ttggactgac caatcgttta aatgcgactt
      541 cgaattactc agaatattca atcagtgtcg ctgttttagc agatagtgat atcgaaaatg
      601 ttacgcaact gacgagtgtg acagcaccga ctgggactga taatgaaaat attcaaaaac
      661 tactagctga tattaagtca agtcagaata ccgatttgac ggtcgaccag agttcgtctt
      721 acttggcagc ttacaagagt ttgattgcag gggagactaa ggccattgtc ttaaatagtg
      781 tctttgaaaa tatcatcgag tcagagtatc cagactacgc atcgaagata aaaaagattt
      841 ataccaaggg attcactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca
      901 atatctatgt tagtggaatt gacacctatg gtcctattag ttcggtgtcg cgatcagatg
      961 tcaatatcct gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccac
     1021 gtgatgccta tgtaccaata gcagatggtg gaaataatca aaaagataaa ttaacccatg
     1081 cgggcattta tggagttgat tcgtccattc acaccttaga aaatctctat ggagtggata
     1141 tcaattacta tgtgcgattg aacttcactt ctttcttgaa aatgattgac ttattgggag
     1201 gggtagatgt tcataatgat caagagtttt cagctctaca tgggaagttc catttcccag
     1261 tagggaatgt ccatctagac tctgagcaag ctctcggttt tgtacgtgaa cgctactcac
     1321 tagccgatgg agaccgtgac cgtggtcgca accaacaaaa ggtgattgtg gctatccttc
     1381 aaaaattaac gtcaaccgaa gcactgaaaa attatagtac aatcattgat agcttgcaag
     1441 attctatcca aacaaatatg ccacttgaga ctatgataaa tttggtcaat gctcagttag
     1501 aaagtggagg gaattataaa gtaaattctc aagatttaaa aggtacaggt cggacggatc
     1561 ttccttctta tgcaatgcca gacagtaacc tctatgtgat ggaaatagat gatagtagtt
     1621 tagctgtagt taaagcagct atacaggatg tgatggaggg tagatgaaat gatagacatc
     1681 cattcgcata tcgtttttga tgtagatgac ggtcccaagt caagagagga aagcaaggct
     1741 ctcttgatag aatcctacag gcagggggtg cgaaccattg tctctacctc tcaccgtcgc
     1801 aagggcatgt ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa
     1861 attgcaaaag aagtagcaga tgatttagtc attgcttatg gcgcagagat atactatact
     1921 ctggatgctc tagaaaagct agaaaaaaaa gaaattccta cccttaatga tagtcgttat
     1981 gccttgattg agtttagcat gcatacttcc tatcgtcaga ttcatacggg attgagcaat
     2041 attttgatgt tgggaatcac gccagtaatt gctcatattg aacgttatga tgctttagag
     2101 aataacgaaa aacgtgttcg tgaactgatt gatatggggt gctatactca gataaatagt
     2161 tatcatgttt caaaacctaa gttctttggt gaaaaatata aattcatgaa aaagagagct
     2221 cggtattttt tggaacgtga tttagttcat gtagttgcaa gtgacatgca caatttagac
     2281 agtagacctc catatatgca acaggcatat gatatcattg ctaagaaata tggagcgaaa
     2341 aaagcgaaag aactttttgt agataatccc agaaaaatta taatggatca attaatttag
     2401 gagaaaatat gaaggaacaa aacactttgg aaatcgatgt atcgcaacta tccagagctt
     2461 tatggaaaag aaagttagtc attttattag tggcaattat aacttcttca gttgcttttg
     2521 cctacagtac ttttgttatc aaacctgagt ttactagtac gactcggatt tatgtagtta
     2581 accgtgatca gggagagaag tctggtttaa ccaatcaaga cttgcaggca ggatcatact
     2641 tggttaaaga ctatcgtgaa attatcctat cgcaggatgt tttggaggaa gttgtttctg
     2701 atttgaaact agatttgacg ccaaaaggtt tggctaataa aattaaagta acagtaccag
     2761 ttgatacccg tattgtctct gtttcagtta atgatcgagt tcctgaagag gcaagccgta
     2821 tcgctaactc tttgagagaa gtagctgctc aaaaaattat cagtattact cgtgtttctg
     2881 atgtgacaac actggaggag gcaagaccgg cgatatcacc gtcttcgcca aatattaaac
     2941 gcaatacact aattggtttt ttggcagggg tgagtggaac tagtgttata gtttttcttc
     3001 ttgaattttt gaacactcgt gtgaaacgtc cggaagatat cgaaaataca ctgcagatga
     3061 cacttttggg agttgtacca aacttgagta agttgaaata ggagagagga atgccgacat
     3121 tagaaatagc acaaaaaaaa ctggagttca ttaagaaggc agaagaatat tacaatgcct
     3181 tgtgtacaaa tatacagttg agcggagata aactaaaagt aatttccgtt acttctgtta
     3241 accctgggga aggaaaaaca actacttccg taaatatagc aaggtcgttt gcgcgtgcag
     3301 gctataaaac tcttttgatc gatggcgata ctcgaaattc agttatatca ggagttttta
     3361 aatcgcgtga aaaaattaca gggctaacag aatttttatc tgggacagct gatttatctt
     3421 acggtttatg tgatacaaat attgaaaatt tatttgtagt tcaatcggga tctgtatcac
     3481 caaaccctat agccttgtta caaagtaaaa attttaatga tatgattgaa acattgcgta
     3541 aatattttga ttatatcatt gttgatacac cacctgttgg aattgttatt gatgcggtaa
     3601 ttatcactca aaagtgtgat gcgtccatct tggtaacagc aacaggtgag gcgaataaac
     3661 gtgatgtcca aaaagcgaaa caacaattag aacaaacagg gaaactgttc ctaggagttg
     3721 ttttaaataa attggatatc tcggttgata agtatggagt ttacgcttcc tatggaaatt
     3781 atggtaaaaa ataacttagg aaagatttta tggataaaaa aggattggaa atttttctgg
     3841 cagtattaca gagtattatt gtcattttat tggtttattt tcttagcttt gttagagaga
     3901 cagaacttga acgttcttcg atggttatac tataccttct ccactttttt gtattctatt
     3961 ttagttccta tggtaacaaa ttttttaaaa gagggtacct agttgagttt aatagtacta
     4021 taagatatat ttttttcttt gcaatagcta taagtgtatt aaactttttt atagcggaac
     4081 ggtttagtat ctctagaaga ggaatggtat acttcttaac tttagaagga atatccttat
     4141 acttgttaaa tttcttagta aagaaatatt ggaagcatgt gttttttaat ccaaaaaata
     4201 gcaagaaaat tttactgtta acagtaacgg aaaatataga aaaagttctt gataaattgc
     4261 tagaatctga tgaactttca tggaaactgg tagcagtaag tgttttggat aaatctgatt
     4321 ttcaacatga taaaatacct gtaattgaaa aggaaaaaat tattgaattt gcaacgcatg
     4381 aagttgtgga tgaggtgttt gtcgatcttc caggagagag ctatgatatt ggagaaatta
     4441 tctctaagtt tgagacaatg gggatagatg taactgtaaa tcttaatgca tttaataaga
     4501 atttgggtcg taataaacaa attcatgaga tagtaggatt gaatgtagtc actttctcta
     4561 caaattttta taaaactagt catgtgattt caaagagaat tctcgatatt tgtggtgcca
     4621 ctattggcct tattcttttt gctatagcta gtctagtttt agttccattg attcgtaaag
     4681 atggcggacc agctattttt gctcaaactc gtatagggaa aaatggtcga cattttacct
     4741 tttataaatt ccgttcgatg cggatcgatg ctgaagctat caaagaacag ttgatggatc
     4801 aaaatacgat gcgaggtggt atgtttaaga tggacaatga tcctcgtgtt acaaaaattg
     4861 gtcgctttat tcgtaaaacc agtttagatg agttacccca gttttggaat gtctttatag
     4921 gagatatgag tttggtggga acacgtccac ctacagtaga cgagtatgat cagtatactc
     4981 cagaacagaa acgtcgactc agctttaaac ctggtattac aggtttatgg caggttagcg
     5041 gccgtagtaa aataaccgat tttgacgatg ttgtaaaatt agatgtggct tatattgata
     5101 attggacaat ctggaaagat attgaaattt tgcttaaaac tgttaaagtt gtatttatga
     5161 gaaatggagc gaagtaaggg atgaaagtat gtctagttgg atctagtgga ggtcatttaa
     5221 ctcatttgta tttattaaaa cctttctgga aagatagaga aagattttgg gtgacttttg
     5281 ataaagaaga tgcaagaagt attttagaaa atgaaatatt ttatccatgt tattatccta
     5341 ctaatcgtaa tctaaaaaat cttattaaaa atacgattct tgctttcaaa attttgagaa
     5401 aggaacgccc tgatattatc gtctcatcag gggcagctgt agcagttcct ttcttttatc
     5461 tagggaaaat atttggtgct aagacagtct atatagaagt atttgataga attgatgctc
     5521 cgacaatgac tgggaaactt gtttatccag taactgacag gtttattgta caatgggaag
     5581 aaatgaaaaa agtatatccg aaagcaatca atctcggagg gattttctaa tgatttttgt
     5641 gacagtaggt actcatgaac aacagtttaa tcgacttata aaagaggttg atagattaaa
     5701 aggtgaggga tttattcagg atgatgtttt tattcaaaca ggatactcta attatgttcc
     5761 aaaattttgt aaatgggaaa aattaatatc ttatgaaaaa atgaatcaat tgattaagga
     5821 atcagatatt atcattaccc atggcggtcc agctacgttt atggcagtta ttgctaaagg
     5881 taaaaatcca ataattgttc cgcggctaaa aaaatttggt gagcatgtaa atgatcacca
     5941 gatgcaattt gtaaaaataa cgaaagaaat atacaattta atagttatag atgatatttc
     6001 agacttacat ttaattcttc ataattttaa ggacaaacat tttgaaactt atttgaataa
     6061 cgagagattt aatgtacgtt tcaatgtgga aatcagtaac ctttttaaag gaaataaaat
     6121 aaatgaaaat tagaatagaa cctcagtatt ttctttataa atacctttgg tttattatcc
     6181 tacttccaaa acagtttatg caattaatat tattcttttt aattgcttta actcttttac
     6241 caacctatat aaaagaaaaa caagttttta aaatagatac accgtctttt tgtatggtgc
     6301 tatggactat tatatattct atatctataa tatttaattc tctgattgat ggattggctg
     6361 ttcaagtgat attttcagat ttgagtaaag catttaattg gctaatagca gtattttttt
     6421 ataattatta tttgaaaatg ccaatcaata ttgacaggat aaagagatat atgtattata
     6481 attttactat cttagttgtt tttgtcggtt tattctatat acaaagaggc tccaatgtaa
     6541 ttttgtttgg aagaagtttg ttagactggg acggatttac attagctact agttatggtg
     6601 taagatatac aggtttttta gaatacgcaa ctttaaatgg tcagttaatt ctttttttat
     6661 taccgttaat tagattgttt agatttagat tttttacaca aactatcatt tttgcttttc
     6721 ttctagaggt tttggtacta agcaaatcta gaatagcgat tgttgcaatg cttatatata
     6781 tagcatttgc agtagtcaat gagattaatt caaacaataa atggcttatt ggaattttct
     6841 gtccaattat tccttttatg ttattttaca attttgaaaa aattaaacag attttttttc
     6901 aaatgtttag ttctagatcg ggtagcaatg cgacacgctt tagagtgtat gaggaatccc
     6961 taaaagctat taatggaatg gaaatgttac ttggcgcagg tgtcagaatt ccctctacag
     7021 tagatatatt attggggtca cattctatgt atataagttt tatttatagg acaggagttt
     7081 taggaagtat aataataaca gtaatgtttt attatctgtt ttctaaattt ttaaaatgtg
     7141 attcatctga gagactaaga agtattggct atattctagc tttgtcagta ttttggcttt
     7201 ttgaagagtt agatccacat tattggtgtt taattttatt tttttcaaca ataagtattt
     7261 tcataaacaa tagaaaagag gaaatagttg gatgatagaa gtatcaatca taattccaat
     7321 atacaatgct gaaaaaacta ttaaaaattg tgttgatagt gccttaaagc aaaatttaga
     7381 atctcttgaa gtgattttgg tgaatgatgg gtctaacgat tctacatcaa aaattcttga
     7441 acagtatggt gataatcccc aagtgatgat tttccatcaa gtgaacatgg gagtatctgc
     7501 tgccagaaac gtaggattat cgtatgcaag cggagagtat gtgttctttt tagattcaga
     7561 tgatatatta gatgaaggta tgctatctaa aatgtatcag tttgcaaaaa gtaataaaat
     7621 tgatctttta tcttgttggc ataaagagcc tagtacaaca caatacggtg gtaatgataa
     7681 tagttcagct tcatttattg cacgaacaaa agaggaaata ggaaatcatt ttgtggatat
     7741 ttttccgaga agtgcttgtg ctaagttatt tcttcgtaga agaattgagg aaaacaatat
     7801 tgctttttcg actgaaatgt cactaggaga agatatgtca ttcgtttgcc aatacttgat
     7861 ggtctcaagg agtattgcag taattgatgg actgtattat actattcaga atgttaatcc
     7921 acagtcatta tctaagcgat atgtaagtaa tatcgaaaac tccctattaa tgcagaatca
     7981 gttatgggat caattattag aagtttatcc taaaattgag gagaactact acaagcaaca
     8041 tatggatttt agattttatc ttgctagttt atatgtgaat aatttattta aatttgattc
     8101 tccgtattcc tcaaaagaaa aatgggataa tattgcacaa caattaaaaa aatatagacc
     8161 atttttagat gagaaagtga gcaaagaaaa gaagcctaaa aatatgaatg agatggtcat
     8221 tttttattta ctgaagtcta aaattcccgc gttaatctat tctttttact catttaaaga
     8281 atggtggaag aaaaagcgat taaaaaattg aaggagaaat cagttatgga agatttagta
     8341 agcattgtcg ttccggtcta taatgtagaa aaatatttaa aaaaatcaat agaaagtatt
     8401 ttgaatcaaa cgtatgataa ccttgaggtt ctattagtcg atgatggcag tacagatagt
     8461 agtggggaaa tttgcgattc atttattaaa gttgattcaa gaataagagt gtttcataaa
     8521 gaaaacggtg gtttatcgga tgctcgaaat tttggaatag agcatatgaa aggccaatat
     8581 gtatcgttta ttgatagcga tgactacata tctaaggatt atgtctggaa gttgtattct
     8641 tctataaaaa ataatgattc cgaggtgtct atatgttctt tttcattggt tgatgaaacg
     8701 ggtgaaaaga taaaagatga gctactagat tctggggaag tatccttgtc tggtcaacaa
     8761 atattagaaa aagcgttaac agcagatggt tatcgctatg ttgttgcttg gaataagctt
     8821 tatcggtcaa ctttatttga aaaattaaaa tttaaaaaag gaatgttgta tgaggatgaa
     8881 tttcttaact atcctctatt ttgggactgt aaaagggtat caattgtaga ggagccgtta
     8941 tatttatacg ttcaacgaaa aggaagcatt atacaaagta atatgacttt agaaaaaata
     9001 aagatgaagg ataaaatgca tacatcgcgt attgaatttt atgcagaaaa aaagaattcc
     9061 tttttacacc aacgttcgtg tcaacagtat tgtaactgga ttgttacaat aaccgttagt
     9121 cattacaatg ttttgaatgt agccttttta aaatatttgc aacatcagtt tagaagaatt
     9181 gttaaatata cacaaaacga tgataagaaa ctgattatac agaatatttt aggctatata
     9241 aatattcgtt tagcagctta tgtaaaatca aaagtaatgt agggtgtaag gagaaataat
     9301 gctggaaaaa attttagctt ctattaacaa tcgctctttt ttagtaaatt gaaaaataaa
     9361 attcatagaa tgtttccgat atatattatc agcaatcaaa atatagcttt tcaacaagag
     9421 attgatattg cttatagaaa aatgaagcga caatttagcc atatttcgtt gactgaaagt
     9481 gaacagaaaa atgatatgaa catttcgaat aaagtttgga tttgttggtt tcagggcgaa
     9541 gaacgccctc cggagttaat tagaacatgt attcaatcaa tgagaactca ttttcttgga
     9601 agagagatta tcgtactgac agaagaaaat ataagtgact atatagatat accagattat
     9661 atcactgata aatataaaaa gggttcgatt tctcgtgcac actattcaga tatccttcgg
     9721 gtagaactct tatgtcgtta tggaggatta tgggtagatg taacagtgtt gaatacagga
     9781 ggagatttct caaatcttga gttgccactt tttgtatata aatctttgga tttatcaaga
     9841 aaagattctc aagccattgt agcatcaagt tggttaattt cgtcatatag taatcatcct
     9901 atattgctgt atgcgagaaa actactctgg gagtattggc gtagaaaaaa tagtttatgc
     9961 aattattttt tatttcatat attctttaca atagctacag agctgtaccc aatcgaatgg
    10021 tctgctgtcc ctacttttaa caatcattct cctcatatgc ttaattttga gttaaataat
    10081 caattttcag aaaaaaggtg ggaacagcta aaacagatat cggtatttca taaattaaat
    10141 catcatatag attattctat cggtgttaac aatttttata agtttatagt atcttcgaaa
    10201 gttgagaaaa atgagtaata aaatcagtaa aaatttagcc tacaatatag gatatcaatt
    10261 aattggtatt gcctttcctt tgataacttc tccttattta tcacggatat taggcgctga
    10321 aaatttaggt attcattctt ttactatctc agtagcactt tactttatga tgtttatgct
    10381 acttggaatt gcaaattatg gaaataggac aatagcgacc gttaaacgag aagggaaaga
    10441 gattttatca aaaacgtttt ggaatatcta ctatgtccag ttgctaatgt cggttctagt
    10501 aactatcgca tatctcattt atttatattt ttgggtgtcg agttacaagt tcattgcgat
    10561 tttacaactt tttttgttat tatcgaatgc agttgatatt acttggttat tttatggatt
    10621 agaagatttt aaacaaattg tttttagaaa tacattagtt aaacttcttg gtttgttttt
    10681 aatattttcg tttgtacatg aaagctcaga tttatggaag tacaccttaa taaacggagg
    10741 agtgacttta gttgggcaac ttttgttgtg gggacaatta aaaggcagat tatcttgggt
    10801 gaagattcaa aaaaaggatt tactatctca tatcaaacca attttagttc ttttcattcc
    10861 tgtgttagca atcagtatct ttagtaatat ggataaatat atgcttggtt taatggttgg
    10921 tgttaagcaa gttggatttt atgataatgc aaatcgtatt atcgatattc ctaaagcatt
    10981 aattgcagca ttagaggctg ttatgttacc acgaacatct tatttattag cagaaggtca
    11041 ggaggaaaaa agtaattact atatagaggt tacaatcctt tatgcgatga tgatttcgag
    11101 tgtattgata tttggtataa tatcggtttc tgatattttc tcgcttgtat tttggggaga
    11161 agaattcctt gaatcaggaa gattaattgc tgctatggca ccagtttttg ttttttctgt
    11221 tccaggaaat ataattagaa cacagtattt gattcctaga gcaaaggata aagattatgt
    11281 gttgtctcta ataataggtg ctctagttaa tatattattg aactgtttct taataaaacc
    11341 ttttggagcc atgggtgcta cgattagtac agttttggca gaatttgtct tgtatggagt
    11401 gcaattttgg acagtcagaa gagatttaga ctttaaaaaa tatttaaaga atggttttat
    11461 attttaccta tttggtatga ttatgtattt agctattata gcagtaaaag ctcatttgca
    11521 atataatata ataaatctta ttctccttat agtgctggga ggaatagtat atactggctt
    11581 ttgttgtttc tacattttaa tatcaagaaa cgtacatttt gagatattac gggaaaaaat
    11641 taaacgaaag attggttatg aaaatatatt ataaattatt attaaagaga ttaatatttc
    11701 ccccctttta attggttacc aataaatatt ggttaccact aaataaaaga aaagttgtat
    11761 ttgataactt tggtggtaga ggatatggag acaatccaaa gtatattgct gatgaactat
    11821 taaaacaaga tgagaatctt gatttagttt gggtagtgga aaaatatgag tatttttgtt
    11881 ccaaaaggag ttagaaaagt atggtatgga agttggagag cttttttgaa tggagcaccg
    11941 caaaggtatg gattgacaac attagaaatt cagatcgtcc ttggaaaagg aaaaatcaag
    12001 tttatttgca aacatggcat ggttctgatg gagttaaaat aatcgaaaaa gatgtagagt
    12061 caacactttc aaaatcatat atcaggatgg ctaaatacga tggtagcatc tctgatgcaa
    12121 tcatttctag ttgccaactg caaacacaaa cagaacagtt ttcaaaatca ttttggttgg
    12181 ctgataatgt tgaaatcttg gagtatggtt taccaagaaa tgatgatttt tttcaaaaaa
    12241 agaaagttga ccatataaac catacagtca gatctaagta taatatctcc ctagatgaat
    12301 tggtaatttt gtatatgcct acttttaggg atgatgcttc aacgaaggcg tataatcttg
    12361 attacgataa ggtaataaat tcatttcaag atttttatat aacagaaaag ttaaagtatt
    12421 gattcgtttt catccaaatg tagatgatac attttttaat aatactgata aaagattaat
    12481 taatgtgaca gattatccta atccgcagga tttaatgttt gtggctgata ttatgatttc
    12541 agactattcg tcagcaccca tagatttttt gttattaaat cgagtagtct ttcttatcta
    12601 ccagatttta aagaatatca gagcgataaa aatccgtttt ttgaagtttt caaagtttcg
    12661 aaaaccaaag gcattgcgct tgatctgttt gatgagatta ttggtcgctt ccagtttggc
    12721 gttagaatag tgtagttgaa gggcgttgat aatctttttg gagtttacag aaagaattaa
    12781 ctagaacata agtagaaaaa taattgttaa aattgataca aaacaagaaa aaggcgggaa
    12841 ctaaaaagtg aaaaaatcta taatgacaaa ttttgttaaa tttagaaaaa acaatttaac
    12901 tagacgcaaa ggaatattga gctttgttgt agcgtttacg ctcttactta cttacttact
    12961 tacttactta cttactgcgt cgcgacccgt atttgcaggg ggatttccga atgatgcaaa
    13021 aggaatatca gggaacggta aatattattc tttaggacaa attgaaaaat tatattctaa
    13081 tcaattcgca acgtataata atttgacggt gattacatct gatacacacg agaactctga
    13141 taattttgcc ttttgtttag cgaatggaaa aaggtttcca tcatttactg atgagaaacc
    13201 taaaggaatc tacaccttgg ttaaagatat taataaggag cagtatacta agttactaaa
    13261 agagaaccat aaatggtcat caattccaaa tcttaatcaa gcatgggata ctttctcaag
    13321 attatcttat atgtatttga aagatcccac tgatattgtt aaaagagcct ggggaaccga
    13381 tttaaataca gctcgaactt attttcatca ggttatacag tacgaaatat ggagatatac
    13441 ggatggtatg agagtatcta gtgatacaaa catctatata tacgaaaaat tttctccgca
    13501 acaaaaaaag gccttggaaa tgattcgtac tgacttatat aattttacag tcccatatga
    13561 aaatcttgaa tatagatttt ataagccaga ttgggtattt ggtttaggat ttcaagcttt
    13621 agcaacagtt agatggaaaa ttgaaccagc taccattact gttactaaaa aatgggaaaa
    13681 tgtaaaagaa ggagctgaaa agcctgaggt ctggattcaa ttgctcaaag atgacaaacc
    13741 tgaaggggat cgaaaacgta tagagccaga taagggtcgg actacatttg aaattccaaa
    13801 taaggatgag attaacaaat attctgtaaa agaagttgat aaagaaggtc gcgattggaa
    13861 acataaagac tttacagcag gtcaacctgt aaacaaagga aatggtcact ttgaaattac
    13921 caatactaaa aaagagaaac ctaaaataaa agttacattt aaaaagattg caggcgacac
    13981 aaataaagat ttggcaggcg cacatcttgt cttaaagaaa atctttgatg atggtaatgg
    14041 tttgctgata aaacaatggg atacaattgg acagcctgtt gatatcgacc tggatgcagg
    14101 ctcctataca ttaacagaag aaaaagcacc agatggctac atgctagctg cacccgtatc
    14161 tttctatgtg gaagaagatg gacaaattat cctaccaaaa ggtgaggatt tagaagctca
    14221 gaatgataag accatcacga tggtggatga aaagat
//
LOCUS       DAVHSH010000046        14116 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000046 DAVHSH010000000
VERSION     DAVHSH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.046"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            38..241
                     /locus_tag="VVR08_001576"
     CDS             38..241
                     /locus_tag="VVR08_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEU6075468.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGYVAGSIV
                     DTAIDDFTNQCRKNPHQWFCVRV"
     gene            559..762
                     /locus_tag="VVR08_001577"
     CDS             559..762
                     /locus_tag="VVR08_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pncT"
                     /protein_id="HEU6075469.1"
                     /translation="MEKIDYITLNEVELETISGGDDCFIGDIGCIGWGLLKSIGGMIK
                     PAPYVPPVCIPKSSWNPAPPVPC"
     gene            1850..2554
                     /locus_tag="VVR08_001578"
                     /pseudo
     CDS             1850..2554
                     /locus_tag="VVR08_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            2704..2958
                     /gene="blpM"
                     /locus_tag="VVR08_001579"
     CDS             2704..2958
                     /gene="blpM"
                     /locus_tag="VVR08_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU6075470.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            2974..3177
                     /gene="blpN"
                     /locus_tag="VVR08_001580"
     CDS             2974..3177
                     /gene="blpN"
                     /locus_tag="VVR08_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU6075471.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            3421..3570
                     /gene="blpO"
                     /locus_tag="VVR08_001581"
     CDS             3421..3570
                     /gene="blpO"
                     /locus_tag="VVR08_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU6075472.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            3674..3793
                     /locus_tag="VVR08_001582"
     CDS             3674..3793
                     /locus_tag="VVR08_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU6075473.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            4579..4962
                     /locus_tag="VVR08_001583"
     CDS             4579..4962
                     /locus_tag="VVR08_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6075474.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            5014..5703
                     /locus_tag="VVR08_001584"
     CDS             5014..5703
                     /locus_tag="VVR08_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075475.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            5745..5993
                     /locus_tag="VVR08_001585"
     CDS             5745..5993
                     /locus_tag="VVR08_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075476.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKNDV"
     gene            6023..6634
                     /locus_tag="VVR08_001586"
     CDS             6023..6634
                     /locus_tag="VVR08_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075477.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            6795..7589
                     /locus_tag="VVR08_001587"
     CDS             6795..7589
                     /locus_tag="VVR08_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU6075478.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            7586..8221
                     /gene="trmB"
                     /locus_tag="VVR08_001588"
     CDS             7586..8221
                     /gene="trmB"
                     /locus_tag="VVR08_001588"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU6075479.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            8347..8826
                     /gene="rimP"
                     /locus_tag="VVR08_001589"
     CDS             8347..8826
                     /gene="rimP"
                     /locus_tag="VVR08_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU6075480.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            8870..10006
                     /gene="nusA"
                     /locus_tag="VVR08_001590"
     CDS             8870..10006
                     /gene="nusA"
                     /locus_tag="VVR08_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU6075481.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            10028..10321
                     /locus_tag="VVR08_001591"
     CDS             10028..10321
                     /locus_tag="VVR08_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU6075482.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            10314..10613
                     /locus_tag="VVR08_001592"
     CDS             10314..10613
                     /locus_tag="VVR08_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU6075483.1"
                     /translation="MNKQKMSNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            10630..13395
                     /gene="infB"
                     /locus_tag="VVR08_001593"
     CDS             10630..13395
                     /gene="infB"
                     /locus_tag="VVR08_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU6075484.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAEPVAPKTEKVAAKPQSRNFK
                     AEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQ
                     QGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKE
                     ALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRD
                     DYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFH
                     ELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYG
                     IEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRV
                     ATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDG
                     VMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVE
                     ISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGT
                     LNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEK
                     SARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSA
                     SLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVE
                     IRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKV
                     ARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAY
                     VMEEIKR"
     gene            13646..13996
                     /gene="rbfA"
                     /locus_tag="VVR08_001594"
     CDS             13646..13996
                     /gene="rbfA"
                     /locus_tag="VVR08_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU6075485.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         4406 a         2394 c         3104 g         4212 t
ORIGIN      
        1 caagacaaaa attaaaaata aaaaaggagt atttgtcatg aatacaaaaa tgatgtcaca
       61 attttctgtt atggataatg aaatgcttga taggatagag ggaggaatat ttggagttga
      121 cgatgctttg ttttgggcag ggttaggcta tgttgcaggt agcattgttg atacagcaat
      181 tgatgatttt acgaatcaat gccggaaaaa tcctcatcag tggttctgtg ttcgtgtata
      241 gatatagtag tgttgtattg tataagaatt tatataactt aatgacctat gcagtgatag
      301 aaactattct tttgcaaacg agtcgcttat tctgttataa gtttacgtgc tcctagtcac
      361 agttcttgtg cttgatagaa agaatgacac ctataaaaat gcgagatatt ggctatatca
      421 ctcacttatt cacctccccg tgatttgtag tagtgatagg ttttctcact attattataa
      481 acattataaa ataaagagta caacactttt tcattctgtg ttgtgccttg agtaaaacga
      541 aaggaatgaa ttataacaat ggaaaaaatt gattatatta ctttgaatga agtagaatta
      601 gagacgatta gtggtggaga tgactgtttt attggagata tcggatgtat cggctggggg
      661 cttttgaaga gtatcggagg gatgataaaa cctgctccat atgttcctcc agtatgcatt
      721 ccaaaaagtt cgtggaatcc tgcacctcca gttccatgtt aaaaagttat tgtaaactta
      781 tataaaaaat gaataatcga cttgttcgct attttgttga atcttcgcaa ttataatata
      841 caggtgttgt tcaggattat tttagcttat tgcaagagtc gaaaactaga aactaatggc
      901 tggttggaac gttaaaaatt cactttctaa ccagctaata ctgcttcaaa taatttctga
      961 acaagtctaa taaataaaac gaataagata gattattaac acagtcttgt tcgttttttc
     1021 tcatatatta tttaattaat aatattataa aattggaaag cagtagggat gggaagtact
     1081 accacagatt tattattaat tttatcagta ttgtttgaaa tccaaaaaaa gtatgttaag
     1141 ctatatttat ttggttcttt agtttgattg ttgttgagta taactatttt tgtatagatg
     1201 aaaatcttgt tattgttcaa gatgttttga tgaccattca tgatttgagt aatccaaggt
     1261 caaaatgagt gctatactag cagtgtaaag attcttgttc aactaagata aatcacacat
     1321 ttaggaggaa attttatgaa gaaaaaaata cttatcattt tcatcttgta tctaatcatg
     1381 tccatctttc tttatccgct tagggaaagt atttggtatc agctatttta taccatagcc
     1441 tatgtgattg cagttatgat ctattttgct ttaactaaaa agaaaggagc aaagaaatga
     1501 aaacttttct tgctaaaaaa cggaacatct tcctttcatt tggggattga agtattataa
     1561 aaagtagagc ttaataaagt ataaaggggt aagtgttttt gaaatactta cccttttata
     1621 atagattccc tgcgaaacaa aatatggtat agtatagtag attgaaacta gaatagtacg
     1681 tctctacttc taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt
     1741 cttatttcat tttactatag ttctatgaat gatgaagcaa gtaaacaact aactgatgca
     1801 cgatttaagc gtcttgttgg ttggtgttca gcgtaccact tttgaagaga tgttagctgt
     1861 attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct
     1921 agaagacctt cttatggcca ctcttcaata tgtgcgagaa taccgcactt atgaagaaat
     1981 tgcggctgat tttggtatcc acgaaagcaa cttaatccgt cggagccaat gggttgaagt
     2041 aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagctctg aggacacggt
     2101 aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaaacaatta gcgaatcatt
     2161 ctggtaaaaa gaaatttcac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa
     2221 ttgtttctat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata tcggacaagc
     2281 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca
     2341 aacttcacgt aaatccagca aactcaagcc gctaacagtt gaagataaag cctgtaacca
     2401 tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa
     2461 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggactacgaa tgaatttgag
     2521 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta atgtaatttt
     2581 tgcaattcaa gacgtttcga tgactattca agatctggat gaaaaatttt aaaaaacgat
     2641 gatatactaa acttgtcaaa gttacaacaa gacaaaaatt aaaaataaaa aagagtattt
     2701 gtcatggata caaaaattat ggaacaattt catgaaatgg atataactat gttatctagt
     2761 attgaaggag gcaagaataa ttggcaaact aatgtcttag aaggtggtgg tgctgctttt
     2821 ggtggctggg ggctagggac agctatttgt gctgcgagtg gtgttggagc accatttatg
     2881 ggagcatgtg gatacatagg agctaaattt ggtgtggatc tttgggcagg agtaacaggg
     2941 gcaacgggtg gattttaata aaaggagact tgtatgaata cttattgtaa tataaatgaa
     3001 acaatgctga gtgaggttta tggaggtaat tccggaggag cagctgtagt tgctgcttta
     3061 ggttgtgcag cgggtggagt gaaatatggg agacttctag gaccatgggg cgctgcaata
     3121 ggaggaattg gaggagcagt ggtttgtgga tatttagcct ataccgctac atcataaaaa
     3181 tgaaagctaa attttatgaa ggctatattc tttattattc tcttcgcttt tcaaacctat
     3241 cttatttatc tatccataag tatctccgat aaaaaacaaa agactattga attaacatca
     3301 ttgaattgtt ttgtcatatt atttctaatc tatgataaat taatttttct ctttattgcc
     3361 tatgtttttt tgataatttt tatattaaac ttgttccgta actgaaaagt gatatactat
     3421 atggatacaa aaatgatgtc acaatttgca gttatggata atgaaatgct tgcttgcgtt
     3481 gaaggtggag atattgattg gggaagaaaa attagttgtg cagcaggggt tgcatatggc
     3541 gcaattgatg ggtgtgcaac aacggtttga catttctatt gggaccattt gctataggaa
     3601 taggtgtaac tggtgctgca ggtggagcta tacttggagg tgtagcctat gcagcaatat
     3661 gttggtggta attatggatt ttaaaagttt tattattggt ttagtagttg gtatatttgg
     3721 tccttatatg gatgacttaa ttagaaaaat attttcaaaa tcttccaaaa aggatacgga
     3781 tagtactctc taaaaaataa atttctcccc tgtatttgct agcttaattt acaggggagt
     3841 ttctttaata ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa aagtctacaa
     3901 acaagttggt atcaatacaa tataaagagg aaagtatgtt tttaatgctt actttttaaa
     3961 ttttttaaca attcaagatg tttcgatgac aattcaagat ttggatgaaa aattttaaaa
     4021 aacaatgata tactaaactt gtcaaagttg caacgggtgc tgctacatta tgttaaaaat
     4081 cgctcttgat tgataagttg gatttgttag gaaaggagta aataattatg gataagaaaa
     4141 agatagtttc gactataata tgtatagtat ttcttgtagt gtcagtagat aattttttta
     4201 gagacttaac cccgttactg ttcattttaa atattattgg cctgtcttgc ttttcagtgc
     4261 taacatacat taacataaaa gagatactct taaatataag taaatgatga tttggttagt
     4321 cctagaacca atcaacttat gtttatcggc ttggcagatt ttatgtttgt catttgtttg
     4381 tatagaggta tttcagaaac agaattctat caacaactaa tcgcttatat aggtgtattc
     4441 tctgcttgtt tatcacgctt ctgctcatgt ggggcttgaa gtattataaa aagtagcttt
     4501 ctatcctttt ctgacaggat atttgagtag aaggctctat taaattgtta gtgaaataaa
     4561 tgaatggagg tatttaatat gaaatacaga ttattttttg ttattttctt gagtagtgtg
     4621 ttggatattc ttttagggac atttttacaa atctctatcg tatctattgg gtggcttgtt
     4681 ctttacagtg gtttgtttga agcaggagtt ttccttcttg ctaataaagg ggtggcggta
     4741 aaaatcaagg aagtagatat tcgaaatcgc tttaaattta tttttggaaa aaccttatgg
     4801 tttcaaattc ttttgctcat ctttttgata atcaaacttt atcttggttt ggatgcgagg
     4861 ttgattttat tctatggaca tattttcatt gtctttaatg ccttaatgta tctattatct
     4921 agtagtcagg ttagccttaa aaaaaacaaa ctgtcttctt aatcttacag cagtagagcc
     4981 tgacaaggtg aggtcatagt agggaggatt tctatgaaaa agtatcaact tctattcaaa
     5041 ataagtgcag tcttctctta cttatttttc gtatttggtc tttctcagct gacgcttatc
     5101 gtccaaaact attggcaatt ttcttctcag ataggcaatt tattctggat tcaaaatatc
     5161 ttgagtttac tttttattgg agtcatgatt gtggttcttg ttaagacagg ccatggttat
     5221 ctcttccgca ttccaagaaa aaaatggctt tggtattcga ttttgacagt attagtggta
     5281 gtgttacaga tctcttttaa cgttcagaca gctaaacatg ttcagtcaac tgcggaaggt
     5341 tgggctgtat tgattggtta tagtgggact aactttgcag agctaggtat ttatatagcc
     5401 ctgttctttc tggttccact gatggaagaa ttgatttata gaggattact gcaacatgct
     5461 ttctttaagc attcgcgatt tggccttgat ttgcttcttc cttccatttt gtttgctctt
     5521 cctcattttt tgagtctgcc tagtctgtta gatatcttcg tctttgcaac atttggaatc
     5581 atctttgccg gtttgacccg ctataccaag agtatttatc catcctatgc ggtgcatgtg
     5641 atcaataata ttgtagcgac cttcccgttt ttgctcactt ttctacatag ggtcttgggg
     5701 taaaaaaaca aaaggcttgc ttttcagcca tagaggaggt catcatgtat aaacacttat
     5761 ttttcctaga ttccaaaact ttagatcggt tgacacccta tattctagtc ttggcttctg
     5821 acaccattgc ttttaatgtt tttgtgctaa cctttgtatc tgcggtggtt tttaatttcc
     5881 taaattccat gctagcttta atggctatat tcataggggc tggctatgtg gtcggatttt
     5941 ggttgctaaa atggtttgtt ttggaaaggc tagaactaaa gaatgacgtg taggaagtct
     6001 gtttgttgag gaggataatt ttatggagtt ttttgataaa tttcatgcct tgtgttttgg
     6061 atttttagta ctaataattg tcattacagt tccttatacg attaaccatg gggatttttt
     6121 tcaaaatgaa tctgcattga ttattgtaag tcttcttgta acctcgctga gtgttgctta
     6181 tgctagaaag tttgaaatga tttcttttgg gatgttaagc aagaaacaac ttttgctttt
     6241 cattgcaatc tttcttctaa gtgtacttga gacgctggtt tatattcatt tcttcgctgt
     6301 ttcttctggc tcaggggtcc aacacttggc ggaagtcagc agaggaattt ccctgtcttt
     6361 gattttaact acctcagttt ttggccccat ccaggaggaa ctcattttca gaggacttct
     6421 tcaaggtgcg gtttttgaca attcttggtt agggcttgtg ctaacttcct ctctcttttc
     6481 tttcatgcat ggaccttcta atgtcccttc gtttattttt tatctacttg ggggcttgtt
     6541 gctgggcctt gcttataaaa agagccaaaa cctatgggtt tctactctag tccacatgtt
     6601 ttacaacagt tggccactcc tatattattt ataaaaatta tgaaaaggta agcagaagac
     6661 ggtgcttacc tttttcaagc tataatgata cccaagccaa tccagaggct tttctttgag
     6721 aatcgggtta gagtggttga cgaataggcc aaaaactagt agaatagtaa ggaaacttta
     6781 tacggaggaa agaaatggat ttgggtgata atgagctaac actgactccc atacctggga
     6841 aaagtggcaa ggcttatatg ggtagctatc ctgatgggaa gcgcatcttt gtaaaaatga
     6901 acacctctcc aatcctacct ggtctagcta gagaacaaat tgctccacaa ttattatgga
     6961 gtcgtcgttt ggcagatggg cgtgatatgt gtgctcaaga atggttgaca ggcaagatat
     7021 tgacccccta tgatatgaat cgtaagcaaa tcgtcaatat tttaacccgt cttcatcgct
     7081 cacgtccgtt gatgacacaa ttgagtcgtt tgggctatgc catggaaaca cctgtagatt
     7141 tactacagtc ttggcaagaa acggctccag atgctttgcg taaaaatcat tttatcagtg
     7201 aagtgatggc tgatttgcgt cagactattc caggatttag agaggaccat gcgaccattg
     7261 tccatggaga tgtacgacat agtaattgga ttgagacaga tagtggcttg atttatttag
     7321 tagattggga ttcggttcgc ttgaccgatc gcatgtttga tgtggcccat atgctctgcc
     7381 attatatttc agaacatcag tggaaggaat ggttgaccta ctacggttac aagtacaatc
     7441 aaacggtatt aagtaaattg tattggtatg gtcaattgtc ttatttgagt cagatttcca
     7501 agtattatat gaaccaagat ttagaaaatg tcaatcggga gattcatggt ttgcgtcatt
     7561 tccgagacaa gtatggaaag agaagatgag agttagaaat cgtaaagggg caacagaatt
     7621 actagaggca aatccccagt atgtggtcct caatcccttg gaagccaagg caaaatggcg
     7681 ggacttgttt ggcaatgata atcccattca tgtggaagtt ggaagtggaa agggtgcctt
     7741 tgtttcaggt atggccaagc aaaaccctga catcaactat atcgggattg atattcaaaa
     7801 gtctgttttg agctacgctt tggacaaggt gcttgaagtt ggagtgccta acatcaagct
     7861 cttgtgggta gatggttctg acttgactga ctactttgaa gacggtgaga ttgatcgctt
     7921 gtatctgaac ttttcagatc catggccgaa aaaacgccat gaaaagcgtc gtttgaccta
     7981 caagaccttt ttggacacct tcaaacgtat cttgcctgaa aatggagaaa ttcatttcaa
     8041 gacggataac cgtggcttgt ttgagtacag tttagtgagc ttttctcaat atggcatgaa
     8101 actcaatggt gtctggctag atttgcatgc cagtgatttt gaaggcaatg tcatgacaga
     8161 atacgagcaa aaattctcaa acaaggggca agttatctac cgagttgagg cagaatttta
     8221 agagatagcc taaaattagg ctgtacaagt gcttttgctt tacataagtt ggcaaacgtg
     8281 ctatactgat aataagaata tgaaaagtga ggcggggaaa tatcttcgcc tcttgcttat
     8341 gaggaggtgg acgcaatcgc aacaatcgta gaattagtca gagaagttgt agaacctgtc
     8401 atagaagctc cttttgaact cgtggatatc gagtatggaa agattggcag tgacatgatt
     8461 ctcagtattt ttgtagataa acccgaagga attaccttga acgacacggc agacttgaca
     8521 gaaatgatca gtcctgtcct agacaccatc aagccagatc ccttcccaga acaatatttc
     8581 ctagaaatta ccagtccagg cttggaacgt cctttgaaaa ccaaggatgc cgtcgctgga
     8641 gcggttggaa aatacatcca tgtcggactc taccaagcca tcgataagca aaaggtcttt
     8701 gaaggaacct tgttggcctt cgaagaggac gagttgacta tggaatatat ggacaagacg
     8761 cgtaagaaaa ccgtccgaat tccatacagt ttagtatcaa aagcacgttt agcagttaaa
     8821 ttatagaaaa agaaaggata gcttttgagg attcaaaagt gaagaaaaca tgagtaaaga
     8881 aatgctagag gccttccgca ttttggaaga agacaaggga atcaaaaaag aagatatcat
     8941 cgacgcagta gtagagtcgc ttcgttccgc ttatcgcaga cgctatggtc agtcagacag
     9001 cgtagctatt gacttcaacg aaaaaacagg tgactttaca gtttatactg tccgtgaagt
     9061 tgttgatgaa gtatttgata gccgtttgga aatcagcttg aaagatgctc ttgccattaa
     9121 ttcagcttat gaacttggag acaaaatcaa gtttgaagaa gcaccagctg agtttggtcg
     9181 tgtagcagcc caatctgcca aacaaaccat catggaaaaa atgcgcaagc aaacacgtgc
     9241 catcacttac aatacttaca aagaacatga gcaagaaatc atgtctggta cagtagaacg
     9301 ctttgacaac cgctttatct atgtcaacct tggtagcatc gaagcccaat tgtcaaaaca
     9361 agaccaaatt cctggagaag tttttgcttc tcatgatcgt atcgaagttt atgtttacaa
     9421 ggttgaagac aaccctcgtg gtgtgaacgt ctttgttagc cgtagccatc cagaaatgat
     9481 caaacgtttg atggagcaag aaattccaga agtttatgat ggaactgttg aaatcatgag
     9541 cgtggctcgt gaagcaggtg accgtacgaa ggttgctgtt cgtagccaca atccaaacgt
     9601 ggatgctatc ggtacaatcg ttggacgtgg tggtgctaat atcaagaaga ttactagcaa
     9661 attccaccca gctcgttacg atgctaaaaa tgaccgcatg gtaccaatcg aagaaaatat
     9721 cgatgttatc gagtgggtag cagatccagc tgaatttatc tacaatgcca tcgctcctgc
     9781 tgaggttgac caagttatct ttgatgaaaa cgacagcaaa cgtgccttgg tggttgttcc
     9841 agataacaag ctttctcttg ccattggtcg tcgtggacaa aacgtgcgct tggcggctca
     9901 cttgactggt taccgtatcg atatcaagtc tgctagcgaa tttgaagcca tggaagacgc
     9961 tgcttcagta gagttggaag tagaaaacga tactgtagaa gaataaaagc tgctagagga
    10021 gggaaagatg aaaacaagaa aaatcccttt gcgcaagtct gttgtgtcta acgaagtgat
    10081 tgataagcgt gatttgctcc gcattgtcaa gaacaaggaa ggacaagtct ttattgatcc
    10141 tacgggcaag gccaatggcc gcggcgctta tatcaaacta gacaatgcag aagctctaga
    10201 ggcgaaaaag aagaaggtct ttaaccgcag ctttagcatg gaagtggaag aaagctttta
    10261 tgacgagttg atcgcttatg tggatcacaa agtgaaaaga agagagttgg gacttgaata
    10321 agcaaaagat gagtaatctc ttggggcttg ctcagcgagc agggcgcatc atatcgggtg
    10381 aagaattggt ggtcaaggcc attcaagacg gcaaggccaa gttggtcttt ctagctcatg
    10441 atgctggacc caatctgacc aagaagattc aagataaaag tcattattat caagtagaaa
    10501 ttgtaaccgt gttttcaaca ctggaattaa gcatagcagt cgggaaatcg agaaaggttt
    10561 tggctgtaac agatgctgga tttacaaaga aaatgaggtc tcttatggaa tagaagagga
    10621 ggacatgatt tgtctaagaa aagattgtac gaaatcgcaa aagaacttgg aaaagaaagt
    10681 aaagaagttg tagcgcgtgc aaaagagttg ggcttggatg tgaaaagcca ctcatcaagt
    10741 gtggaagaag ctgtcgctgc aaaaattgct gccagcttta agcctgcagc tgctccgaaa
    10801 gtagaagcaa aacctgcagc accaaaagta agtgcagaaa agaaagccga aaaatctgag
    10861 ccagctaaac cagctgagcc agtcgctccg aaaacagaaa aagtagcggc taaaccgcaa
    10921 agtcgtaatt tcaaggctga gcgtgaagca cgtgctaaag agcaggcaga gcgacgcaag
    10981 caaaataagg gcaataaccg tgaccaacaa caaaacggaa accgtcagaa aaacgacggc
    11041 cgtaatggtg gaaaacaagg tcaaagcaac cgcgacaatc gtcgctttaa tgaccaagct
    11101 aagaagcagc aaggtcagca aaaacgtaga aatgagcgcc gtcagcaaga ggataaacgt
    11161 tcaaatcaag cggctccacg tattgacttt aaagcccgtg cagcagccct aaaagcagag
    11221 caaaatgcag agtacgctcg ttcaagtgag gaacgcttca agcagtatca ggctgctaaa
    11281 gaagccttgg ctcaagctaa caaacgcaag gaaccagagg aaatctttga agaagcggct
    11341 aagttagctg aacaagcaca gcaagttcaa gcagtggttg aagtcgtccc tgagaaaaaa
    11401 gaacctgcag tggatacacg tcgtaaaaaa caagctcgac cagacaaaaa tcgtgacgat
    11461 tatgatcatg aagaagatgg tcctagaaaa caacaaaaga atcgaagtag tcaaaatcaa
    11521 gtgagaaatc aaaagaatag taactggaat aacaacaaaa agaacaaaaa aggcaataac
    11581 aagaacaacc gtaatcagac tccaaaacct gttacggagc gtaaattcca tgaattgcca
    11641 acagaatttg aatatacaga tggtatgacc gttgcggaaa tcgcaaaacg tatcaaacgt
    11701 gaaccagctg aaatcgttaa gaaacttttc atgatgggtg tcatggccac acaaaaccaa
    11761 tccttggatg gggaaacaat tgaactcctc atggtggatt acggtatcga agccaaacaa
    11821 aaggttgaag tggataatgc tgacatcgaa cgtttctttg tcgaagatgg ttatctcaat
    11881 gaagatgaat tggttgagcg tccaccagtt gttactatca tgggacacgt tgaccacggt
    11941 aaaacaaccc ttttggatac tcttcgtaac tcacgtgttg cgacaggtga agcaggtggt
    12001 attactcagc atatcggtgc ctaccaaatc gtggaaaatg gtaagaagat taccttcctt
    12061 gatacaccag gacacgcggc ctttacatca atgcgtgcgc gtggtgcttc tgttaccgat
    12121 attacgatct tggtcgtagc ggcagatgac ggggttatgc ctcagactat tgaagccatc
    12181 aaccactcaa aagcagctaa cgttccaatc atcgtagcca ttaacaagat tgataaacca
    12241 ggtgctaacc cagaacgcgt tatcggtgaa ttggcagagc atggtgtgat gtcaaccgct
    12301 tggggtggag attctgaatt tgttgaaatc tcagctaaat tcaaccaaaa tatcgaagaa
    12361 ttgttggaaa cagtccttct tgtagctgaa atccaagaac tcaaggcaga cccaacagtg
    12421 cgtgcaatcg gtacggttat cgaagcgcgc ttggataaag gaaaaggtgc ggtcgcaacc
    12481 cttcttgtac aacaaggtac cttgaatgtt caagacccaa tcgttgtcgg aaataccttc
    12541 ggtcgtgtcc gtgctatgac caacgacctt ggtcgtcgtg ttaaagttgc tggaccatca
    12601 acaccagtct ctatcacagg tttgaacgaa gcaccgatgg cgggtgacca ctttgccgtt
    12661 tacgaggatg aaaaatctgc gcgtgcagca ggtgaagagc gtgccaaacg tgccctcatg
    12721 aaacaacgtc aagctaccca acgtgttagc cttgaaaacc tctttgatac ccttaaagct
    12781 ggggaactca aatctgttaa tgttatcatc aaggctgatg tacaaggttc tgttgaagcc
    12841 ctttctgcct cacttcaaaa gattgacgtg gaaggtgtca aagtgactat cgtccactca
    12901 gcggtcggtg ctatcaacga atcagacgtg acccttgccg aagcttcaaa tgcctttatc
    12961 gttggtttca acgtacgccc tacaccacaa gctcgtcaac aagcagaagc tgacgatgtg
    13021 gaaatccgtc ttcacagcat tatctacaag gttatcgaag agatggaaga agctatgaaa
    13081 gggatgcttg atccagaatt tgaagaaaaa gttattggtg aagcggttat ccgtgaaacc
    13141 ttcaaggtgt ctaaagtggg aactatcggt ggatttatgg ttatcaacgg taaggttgcc
    13201 cgtgactcta aagtccgtgt tatccgtgat ggtgtcgtta tctatgatgg tgaactcgca
    13261 agcttgaaac actataaaga cgacgttaag gaagttacaa acggccgtga aggtggattg
    13321 atgatcgacg gctacaatga tattaagatg gatgatgtga ttgaggcgta tgtcatggaa
    13381 gaaatcaaga gataagattt tttgctcctt tcttaggtgg tgagggacgc aagcaaaccg
    13441 atggtttcat tgcttatttt tgagcctagg gtctcaaaaa tcccctgtga tgggactgat
    13501 aaatcagttc catcactttc accacggcga aagaagcaga tgacttcaaa ttgaacttcg
    13561 tttcaattta aactgaaaat caagaagttt aaaatagcta ggtctgctgg cctagctttt
    13621 ggttcaaagt agagaaagga atatcatggc aaatcatttc cgtacagatc gtgtgggcat
    13681 ggaaatcaag cgtgaagtca atgagatttt gcaaaagaaa gtccgtgatc cacgtgtcca
    13741 aggtgtgacc atcacagatg ttcagatgct gggtgacttg tctgttgcca aggtttatta
    13801 caccattttg agtaaccttg cttcggataa ccaaaaagcc caaatcgggc ttgaaaaagc
    13861 aactggtacc atcaaacgtg aacttggtcg caatttgaaa ttgtacaaaa tcccagattt
    13921 gaccttcgtc aaagacgagt ccatcgagta tggaaacaag attgacgaga tgctacgcaa
    13981 tctggataag aactaaagaa gaggggttgc ccctcttttt tggtggagga aaataggttg
    14041 aatttgaaat ggaaaaatat tcttttaaaa tatattgaaa ctagaatagt acgcctctac
    14101 ttctaaaaca ttgtta
//
LOCUS       DAVHSH010000047        13417 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000047 DAVHSH010000000
VERSION     DAVHSH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.048"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            1..1064
                     /locus_tag="VVR08_001595"
                     /pseudo
     CDS             1..1064
                     /locus_tag="VVR08_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(1148..2350)
                     /gene="rpsA"
                     /locus_tag="VVR08_001596"
     CDS             complement(1148..2350)
                     /gene="rpsA"
                     /locus_tag="VVR08_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU6075486.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2512..2583)
                     /locus_tag="VVR08_001597"
     tRNA            complement(2512..2583)
                     /locus_tag="VVR08_001597"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2549..2551),aa:Gln,seq:ttg)
     gene            complement(2593..2673)
                     /locus_tag="VVR08_001598"
     tRNA            complement(2593..2673)
                     /locus_tag="VVR08_001598"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2637..2639),aa:Tyr,seq:gta)
     gene            complement(2723..2953)
                     /locus_tag="VVR08_001599"
     CDS             complement(2723..2953)
                     /locus_tag="VVR08_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU6075487.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3121..3765)
                     /gene="pcp"
                     /locus_tag="VVR08_001600"
     CDS             complement(3121..3765)
                     /gene="pcp"
                     /locus_tag="VVR08_001600"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6075488.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3780..4703)
                     /locus_tag="VVR08_001601"
     CDS             complement(3780..4703)
                     /locus_tag="VVR08_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU6075489.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4700..5389)
                     /locus_tag="VVR08_001602"
     CDS             complement(4700..5389)
                     /locus_tag="VVR08_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU6075490.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5454..6158)
                     /locus_tag="VVR08_001603"
     CDS             complement(5454..6158)
                     /locus_tag="VVR08_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6075491.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6214..7236)
                     /locus_tag="VVR08_001604"
     CDS             complement(6214..7236)
                     /locus_tag="VVR08_001604"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU6075492.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7368..9839)
                     /gene="parC"
                     /locus_tag="VVR08_001605"
     CDS             complement(7368..9839)
                     /gene="parC"
                     /locus_tag="VVR08_001605"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU6075493.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10259..12202)
                     /gene="parE"
                     /locus_tag="VVR08_001606"
     CDS             complement(10259..12202)
                     /gene="parE"
                     /locus_tag="VVR08_001606"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU6075494.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVMTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12338..12979
                     /gene="plsY"
                     /locus_tag="VVR08_001607"
     CDS             12338..12979
                     /gene="plsY"
                     /locus_tag="VVR08_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU6075495.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(13022..13417)
                     /locus_tag="VVR08_001608"
                     /pseudo
     CDS             complement(13022..13417)
                     /locus_tag="VVR08_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3872 a         3016 c         2362 g         4167 t
ORIGIN      
        1 ttcaaaaatg atggtcgctg aaacttctat cgtcaagaag aatcatcaaa ttcctcgtat
       61 tatcaaccaa aaaattgcgc aaaagttgat tgagaagatt tctatgaccg atatttctca
      121 tcagctggcc atttcaactt caactgtcat tcgcaagctc aatgattctc actttgagca
      181 tgatttttcg cgtcttcctg agattatgtc ctgggacgtt gaaacagtcc ggggagtgac
      241 tgtttcaatc gggagatgga gatgagcttt attgcgcaag attttaacaa tctcaatatc
      301 atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct tcgctacgat
      361 agagttgtcc gatgtcgcgt caaaattatt actatggata tgtttagtcc ttactatgat
      421 ttggctaaac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc tcccagactg
      481 tttcactccc gaatgctaaa atcgttcttg atcgctttca cattgtacaa catcttagcc
      541 gtgctatgag tcgtgtgcgt gtccaaatca tgaatcaatt ggatcgaaaa tcccatgaat
      601 acaaggctat caagcgctac tggaaactca ttcaacagga tagccgtaaa ctgagtgata
      661 agcgatttta tcgtcctact tttcgtatgc acttaaccaa taaagagatt ttagacaagc
      721 ttttgagcta ttcacaaaac ttgaaacacc actatcagct cttgcttttt cacttccaga
      781 ataaggaacc agagaaactt ttcggactta ttgaggacaa tctgaagcaa gttcatccta
      841 tttttcagac tgtctttaaa accttcttca aagataagga aaagattatc aacgcccttc
      901 aactacacta ttctaatgcc aaactggaag cgaccaataa tctcatcaaa cttatcaagc
      961 gcaatgcctt tggttttcga aactttgaaa atttcaaaaa acggattttt atcgctttga
     1021 acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttt tcaacccact
     1081 acagttgaca aagagccgaa aaatcccttg tttagtaaac aaaggatttt gtgaattttc
     1141 aatttgatta aagttcgata tcaccaaaca aatcagccat tgaaaatcct gtttgtgttt
     1201 ctggaagttc gaaatcacgc ttttcttgac gtcttggacg acgtggacga gcagcacgtt
     1261 tttcttcttt ttgtccttct tcttgggctg gacgttcttc aagagcttta atagaaagtg
     1321 atacgcgttc tgcatctgcg ttaacttcaa gaactttaac ttgaacttct tgaccaactt
     1381 taagagcttc ttttggattt tcaatccgtt tgtgtgaaat ttgtgatacg tgaacaagtc
     1441 catcgatacc tggcaatact tcaacaaatg caccgaagtc agtcaaacgt ttaactgttc
     1501 cttctactac atcaccttta gccaattttt gctcaacgcc atcccatggt cctggtactg
     1561 ttgctttaag tgaaagtgat acacgtcctt cttcttcgtt aagatcaagg attttcactt
     1621 caatttcttc accaacagtt acaactgatt ttggtgatac gttacgttca tgtgacaatt
     1681 cagtcaagtg aaccaatccg tcaacaccac caaggtcgat gaaagcgccg aagcttgtga
     1741 tacgagcaac tttaccagtt acaacatcac caacagccaa tttaccgaat acttcagcgc
     1801 gagctgctgc agtagctgct tcaacaactt cacgacgtga aaggatgaag cggttttctt
     1861 tagcgttaac ttctttgatt ttagtatcaa attcttgacc tacaaaacgc tcagcgttac
     1921 gtacgaaacg agtatccaac attgaagctg ggataaatcc acgaacacct tcaaattcta
     1981 ctgaaagtcc acctttaacg gcacgcgttc ctttaacagt aacaacttct tcttcgcgac
     2041 caacaagttt gtcccatgct ttgcgagctt caaggcgttt tttagataca aggtatgtaa
     2101 ctgtatcagt atctttacca actacttgac gaagtacaag aacatccaat acttctccta
     2161 ctttaacaaa gtcattgata tctgcatcac gatcgtttgt caattcgcga agagtcaaga
     2221 caccttcaac accagttcca gagattgcaa cgttagcttg agtcgcatca actgtcaata
     2281 cttcagcact aacaacatca ccagtctcaa cttgactaac gctatttagc aaatcttcaa
     2341 attcgttcat ctaaaaaatc ctccaacaat caagtttttc ttaaacttga catacttata
     2401 atttttttcc taagcacccg caaggacatg ttcatatcat tcacgtcttt caattataaa
     2461 aataaaatac cctaagatat tttgcttttt atcttgatta ttacctaaga actggggtag
     2521 ctggattcga accaacgcat gagggagtca aagtcccttg ccttaccgct tggctatacc
     2581 ccattaatga aatggagaga gagggattcg aacccccgaa cccgaaggag cggatttaca
     2641 gtccgccgcg tttagcctct tcgctatctc tcctacaatc aacatggact attatatcat
     2701 gaaaatttca aaaaaacaag acttattttg ctaaattata attttcaatc aaaatttcca
     2761 cagctttttc caatttttta taaaaactat cgacattccc attctttata atggcaaatt
     2821 gtccgtctaa ttcggcaatt tctccgataa cttttttacc gatagtcaat gtataacctt
     2881 caaaactgtc tttaccaaca ttaactttgg catccgctac ttgaatttcg atttttttat
     2941 ctttcttgct catttcatac ctctcttcac tttttctatt ttacaagaaa atcctaaaac
     3001 tagcaagaaa aaactctata tcaggcttct ctgatataga gctttatgta aacaacctca
     3061 attgatttag catagttaat agttagtaaa caagcataat tgactatcct ttttaggtta
     3121 tcagtgagtc tcaccgccta ctaactgcaa atccttatct ttgtagtcta caatagcttc
     3181 aatagctacc tctatgcctc ttacaatgtc acatagactc attcctgcag tattcggctt
     3241 atttactact tgttccatca tatatggaat atgcatgaaa cctgctctca tattagggaa
     3301 ttttttatcc actaaataaa gagcttggta catcaaatga ttgcaaacaa aggttcctgc
     3361 actattggat acaactgccg gaagtccctg ttttttgata gcttgtacca tcgctttgat
     3421 aggtaaacta ctaaaatagg ccgatgctcc atcaatacga atcggtgtat caattggttg
     3481 attgccttcg ttatcaggta tgcgagcatc atcttgatta atagccactc gttcaggtgt
     3541 taagccggtc ctgccgcctg cttgtccaat acaaagtaca gcatctggtt gatatcgtaa
     3601 tatttctgcc tctaaaactt ctgacgactt ataaaaaacc gttggaattt ctacccagcg
     3661 aacttcagcc ccattaatct cagatggtaa taattttaca gcctccaaag ctggattaat
     3721 cttttcacct ccaaaaggat taaaacctgt aaccaatatt ttcattttat tttcctttac
     3781 taaaatgcga gaaagtacat taagaatatg tgaataacaa tcattactag agcaacacct
     3841 gcttgagcct ttataacgcc attctgatct ttcatatcca tcaatgctgc tggtagagcg
     3901 ttaaaattag cagccattgg ggtcaataag gtcccacaat aacctgctgt catggcaaga
     3961 gcaccagcca caattggatt agctcccaga gcaaatacaa agggaactcc aacacctgct
     4021 gtaataacgg tgaatgctgc aaaagcattt cccataatca ttgtgaatag aaccattcca
     4081 agaacatagg ccaaaactcc tataaagcga ctatctgaag gaacaatacc gctaatcaga
     4141 tgagaaataa catcaccaac acctgctaca gtaaaaatag cccccaaagc ccctaataat
     4201 tgaggaacaa tcccacttgt tgaaacttgc tgagtcattc gattattttc tgataacaga
     4261 ctcttagggt gactattggt aatcacaaga acagaaattg tagcaaacaa ggcggcaagg
     4321 ctaatcgaaa tcttgctaaa ttctggaatc atttgcgcta agaccaacgc aagtattgcc
     4381 atcagcataa ctggaataaa aattttattt ttcaacctgt tagattcaat attggctttc
     4441 atttcatcta aggatggcaa ggttccgata cggacttgct taaacaatgt taacagcgat
     4501 aataggatta caataatacc aatactcata tttggcatat aggaaccacc tataaacgta
     4561 atagacaata gagtccaaaa tgcagatgtc ccaagtcgaa ctgggtttgt tttatcttta
     4621 taactacaat aggctgtatg gagaaattga caaccaatca caatataggt caactctaat
     4681 agttgctttg ccaactctgt catttttgtt ctcctcccct agtctttttt gatatcaatt
     4741 ttttatcaaa taaataattg taaatcccca ctacaataag tgttataaca gcaacaataa
     4801 tagatgtaga agcaatccct gcataattgc tttcatagcc taactgatct aatgttcccc
     4861 ctatcaagag gactccccca gcacctacaa acgtattttg agcaaagaaa tttccaaaat
     4921 tttcattcgc agccgcacgc gcttttattg tctcatcttc aacctctgtt aactttctac
     4981 ctaattgaga ctctgcagct gcttctccca taggttgaac caaaggtctg acaaactgag
     5041 ggtgtcctcc tagacgaatt gaaaagaaac cagctaactc tcgaataaag aaataaactg
     5101 tatagaagtt tccaactgtc agacctttaa tctttcgaat caaatcgatt gatcgttgct
     5161 tgagtccaaa ggtttctgac agccccacaa gaggcaaggt aaccataaaa atcgtgagca
     5221 ctcgctgatt gctaaattct tttcccaaaa tctccaaaaa ttcaacgaga gaaacacctg
     5281 aaactaaagc tgtaaccaaa ccagctaaga ctactgttgc aattgtatca aattttaaaa
     5341 taaaacccac aacaatgatt gctattccta ttaatctaat ccactccata tcaaactcct
     5401 ttatattcaa aatgacagta ttttaaaaat tttatcaaga tcaataccat tccttattta
     5461 atgtattttt ctagttcttt ttggtatttg ctattggatt ccaatttttc tttttgccat
     5521 tttttaaaaa cctcgttata ttcttttgtt gtaacaatat ctttttgcaa tttcattcct
     5581 ttaaagatat atggttcccc cttaatacca acttgtgagt atggttttga gaatggtact
     5641 acgttactta caactggaga accaccagat gaagctgttg gcatcaataa tgaactatct
     5701 gtcgaccaag cttgagcttt ggcatatttt tcatatctct tctctaggtc agtggtctca
     5761 gaaacagcat cttctaacaa tttcttatat ttatccaaac caggtttagc tacaacatcc
     5821 ttatcttttc ctttcgtaat accaaggtgt ttcatggcag aaccagattt tggatccata
     5881 atattcaagt aagacgctgg atcttgatag cttggagccc atcctgtact attcaaatca
     5941 tagtcttttt gagaaggagc aacattgccg tatttatcat tttccatcaa accatcaata
     6001 acatttccaa taacgtctgt cgtcgatgtt cgagtcgcta tactgtagcc caatgatgct
     6061 ggatctactg catagacata agaaaatgtt gtcggtgcat ctgcttcttt atcagttttt
     6121 ccacaagcca ctaaaatagc taacgtgctc aggaccactc ctgctgttaa gagccacttt
     6181 ttctatttca taaaaaatct cctttggttt attttaatct acttttacaa tccaaccttc
     6241 tggcgcttca atatcgccaa actgaatacc cgtcaattca ttatataatt tacgcgtcac
     6301 aggacctact tctgtttcac tatagaatac atggaaatca tcaccatgtt gaatacctcc
     6361 aattggagaa ataaccgctg ctgtaccaca ggcacctgcc tctacaaaac ggtcaagatt
     6421 atcaattgga acatcaccct caataggagt taatcccaag cgatgttctg ccaaataaag
     6481 caaggaatac ttggtaatag atggcaagat agatggactc aatggtgtta caaattcatt
     6541 atcagctgta attccaaaga agttagctga tccgacttct tcaatctttg tatgagttga
     6601 tgggtccaga tagataacat ctgagaaatg gcgtgacttg gccatttttc ctggtaagag
     6661 acttgcagca tagtttccac caaccttagc cgcacctgta ccatttggtg ctgcacggtc
     6721 gtactcatcc tgaatcaaga agttggttgg gaccaaacca cctttaaagt aatttccaac
     6781 tggcatagca aagatggtga aaatgtactc ttctgccggt tttaccccga taatatctcc
     6841 gacaccaatc aaaagagggc gaagatataa ggttccacct gttccgtatg gtggtacgta
     6901 ttcttcattc gcacggacaa ctgctttaca agcttctaca aacatgtctg tcggaacttg
     6961 tggcatcaag agacggtcac atgtacgttg caggcgttta gcattttcat caggacggaa
     7021 cagttgaaca ctgccatcct tagtacgata agctttcaaa ccttcaaatg cttgttgtcc
     7081 atagtgaaga cttggagaag actctgaaat atgcaaagtt gcatcctctg taagctctcc
     7141 ttgatcccat tgtccatttt tgaaatgagc aagatagcga taaggtaatt tcatatagga
     7201 aaaaccgagg ttttcccaat caatcgttac tgtcatattc cactccttat tctaaaaacc
     7261 tatttcttat attctacact atttttctaa aatagcaagt atattttgta attttcagaa
     7321 aatttctcca ataaaaacca gctcttagaa ctgattcttc atttcactta tttatcttca
     7381 gtaactactt cctgaagata agcgtcaaaa acttcttcat ctgaaatcgt gtcagaaatg
     7441 aagcttccat tgctagtgcg ttctgacaag ttcaagtctt gcaatcggct ttcatagatt
     7501 gttcctttat tggattggac aagcagagtt tggtcgttca catccacttc cgtactgaag
     7561 aaatcgccaa caaatccttg ctctgcaact gctcctgcca agaagacacg atgcggtttg
     7621 tttttcaact cacgcaagac ttgtaatcct cgtttggcac ggctggttgc tagaatttcc
     7681 tcaatggaaa cacgtttcaa gcttccacgc tgggtcaaga ggtagaagga cgaagtatta
     7741 cagataaagc cagattggag gacatcatct tctttcaaat tcatagcctt gacacctgct
     7801 gccttagcac cgacaaccgg aacctcttcg atattgaaac gcagggcata accattttga
     7861 ctaaccaaga caacatcatc tagtttaatc ggagccactg ctacaatctg atctgtatcg
     7921 tctttgagct tagcatactt gacagactta gatctatagg tccgccatgg agtaaattct
     7981 tttcgctcta cccgtttgat ttgaccaagg cgagtcgctg caaagtaggt tgtcgcatcg
     8041 tcaaactgat ccagtacttc cacataaagg attgcttcat tcgtttcaaa gtttgtgatg
     8101 gtttggctca gatgctctcc gatgtccttc caacgaatat ctgccaactc atggattggt
     8161 ctgtagatga catttccaag acttgtgaac atcaagaggt gctgggttgt cttggcagat
     8221 tgaacaaaaa tcaaacggtc atcatcacgc ttgccaattt cttccaaggt ggaagccgca
     8281 aaggaacgtg gactggtacg cttgatgtaa cctgccttgg tcacgctgac gtaggtatct
     8341 tcctcagcga taagactagc tgtatcaatc tcaattgctt tcgcagtgtc ttctaaagaa
     8401 ctcaaacgag gagttgcaaa tttcttcttg acctcacgaa gttctttctt catgagattg
     8461 tacatagtcc tttcatcacc gataatagcc gccagcatag caatcttctc acgaagctct
     8521 gcttcttctt cctgcaagac aaccacatcg gtattggtca aacggtacag ttgcaaagtt
     8581 acgatagcct cagcctgttc ttccgtaaaa tcatagctaa ctttgaggtt ttccttggcg
     8641 tccgccttat tctcagaagc acggataaga gcaatgactt catccaaaat cgaaatcaca
     8701 cgaatcaaac cttcgacgat atggagacgt ttctcagcct tttctttgtc aaagcgtgaa
     8761 cgcgccaaaa tcacttctcg acggtgagcg atgtagctag acaggattgg aacaatccca
     8821 acctgacgag gtgtgaaatt gtcaatcgcc accatattaa agttgtagtt gatttgtagg
     8881 tcggtgtact taaataagta gttgagaaca agctcagtat tagcgtcttt cttaagttcg
     8941 atagcgatac gaagaccatc acggtcagac tcatcacgaa cctcagcaat cccagctacc
     9001 ttgttattaa cacgaacatc atcgattttc ttgactagat tggccttatt gatttcataa
     9061 ggaatctcag taataacgat ttgttcctta ccacctttta gcttttcaat ttcagtcttg
     9121 gaacgaacaa ccacgcgccc tttcccagtc tcataagctt tcttgatttc atcacgaccc
     9181 tgaataatag cccctgtagg gaagtctggt ccaggtaaga attccatgag tttatcaatc
     9241 tttgcagttg ggtggtcaat catgtaaact gcagcatcta tgacctcagc taaattatgg
     9301 ggaggaatgt ctgtggcata accagccgaa atcccagtcg aaccattgac caagaggttt
     9361 ggaaaggctg ctggcaagac cgttggttct ttctccgtat cgtcaaagtt ccatgcaaaa
     9421 ggaactgtct ttttctcgat atcctgaaga aggtagcctg caatttcaga caaacgtgcc
     9481 tcagtataac gcatagccgc aggaggatct ccgtccatag aaccgttatt accgtgcatt
     9541 tcaactagaa tctcacgatt tttccagttc tgtgacatac gaaccatggc atcatagata
     9601 gaagaatctc cgtgtgggtg gaaattcccc atgatgttcc cgactgactt ggccgactta
     9661 cggtagctct tgtcaaaagt attgctatcc ttattcatag aataaagaat acggcgctga
     9721 accggcttca acccatcacg aatatctggc aaagcccggt cttgaataat gtacttggag
     9781 tagcgaccaa agcgctctcc catgatgtcc tccagggaca tgttttgaat gttagacata
     9841 agatacaaag cccataaaat accaagtgaa aatagaaaat tcttgaagta agcaaactca
     9901 caagagaatt tatctttttc acacagtatc tagggcgtgt tcaactcctt tcaaagaatg
     9961 tagagtaggt ttttatgcag taaaagatat tttacgggaa ttcctcccgt gttcagttac
    10021 gataagtaac caaactatcc tgtttgtatt tttcaatatg aaaatctggt tttccaaaat
    10081 tagtcttagt ttgtgtctta gccgctccct taagcgcctc tttgagataa gcactcatag
    10141 cagattcttc attaataatc ctgcaatttt ttcaaaccaa gattttcaaa ctgctttttc
    10201 acatagtcat tcacatccga ctctaatttc cagtttacta acatattatt ttctttcatt
    10261 aaaacactgt cgcttcttct agcgtaaact tgacattatc ttcaatccat ttacggcgtg
    10321 gttctacctt atctcccatg agaacattga cgcggcgttc ggcgcgcgct aaatcttcaa
    10381 ttgtgacacg gatgagggta cgtgtttctg ggttcatggt tgtttcccag agctggtccg
    10441 cattcatctc accaagtcct ttgtatcgtt ggagggtagc gcctttaccg aactgtttac
    10501 ggagttcttc tagttctccg tccgtccaag cgtaggccac ttcttctttc ttgcctttac
    10561 ctttggacat cttgtaaaga ggtgggaggg caatatagac atgacctgcc tcgactagcg
    10621 gacgcatgta acggtagaaa aatgtcaaga gcaaggtctg gatatgggca ccatcggtat
    10681 ccgcatcggt catgataatg atcttatcat agttggcatc ttcaatagag aagtctgctc
    10741 caacacccgc accaatggta taaatcatgg tattgatctc ttcatttttg aggatatccg
    10801 ccatcttggc cttggctgta ttgacaacct taccacgaag aggtagaata gcctggaact
    10861 tgcggtcacg accttgtttg gcagaaccac cggcagagtc cccctcaact agatagagtt
    10921 cattcttagc aggattctta gattgggctg gggtcaattt cccagacaac aagcccttat
    10981 ctttcttgtt tttcttccca tttcggctct catcacgcgc cttacgtgct gcttcacgag
    11041 catcacgggc cttgatagcc ttgcggatga ggttagaagc taattcccca ttttccataa
    11101 ggaaaaaggt caacttatca gccactattc catccacaac cgggcgagct agggggcttc
    11161 ctagtttatc cttggtctgt ccttcaaact gcaagtgttc ttcaggaact aagatagaaa
    11221 gaacggccgc tagtccctca cgatagtctg aaccttcaag gtttttatct ttttccttga
    11281 gaagacctgt tttacgtgca tagtcattca tgaccttggt aatggcagac ttgagtcctg
    11341 tctcgtgcgt tccaccgtcc ttggtgcgaa cgttattgac aaaggataga atgttatctg
    11401 agaatccgtc attgtactgg agggctactt ccacttgaaa accattgtct tccccttcaa
    11461 agtaaagaac tggcgtcaag atttccttat cttcgttgag ataagaaaca aaatcttgta
    11521 ctccattctc atagtggaac tcaatcgctt catctgttcg cttgtccgtt aaagacaagg
    11581 tcacattttt caagagaaag gctgattcat taaggcgctc tgaaatggta ttgtacttga
    11641 aatctgtcgt agaaaagata gtcgcgtcag gcataaaagt aactttggtg cctgttttag
    11701 acttgggtgc tgtaccgact ttcttcaaag tcatgacagg ttttccacca ttttcaaaac
    11761 gttgcttgta aactgcgcca tcacgggtaa tttcaacttc taaccagcta gaaagggcgt
    11821 taacaacgga agaacccact ccgtgaagtc cacctgatgt cttatagcca ccttgaccga
    11881 atttccctcc ggcatgaaga atggtaaaga taacctcaac agttggaatt cccatagcgt
    11941 gcatacctgt cggcatccca cgtccatggt cttgaaccgt tagactaccg tctttattga
    12001 tagttacatc aatacgatca ccaaacccag acaaggcttc atcgactgca ttatcaacga
    12061 tttcccaaac taggtgatga agaccagcgc catcggtcga tccaatatac atccctggac
    12121 gttttcggac cgcatccaac ccttctagca cctgaatagc atcatcatta taattgttaa
    12181 tattgatttc cttttttgac acaaggaacc tcctattcgt tcatctttac tattctacag
    12241 gttttccaag gattttgcaa aatttttctt tctccgatgt gacaatttta gcagagattc
    12301 tctgcttttc tttcccaatt catgatataa taggagtatg attacaatag ttttattaat
    12361 cctagcctat ctgctgggtt cgattccatc tggtctctgg attggacaag tattctttca
    12421 aatcaatcta cgcgagcatg gttctggtaa cactggaacg accaatacct tccgcatttt
    12481 aggtaagaaa gctggtatgg caacctttgt gattgacttt ttcaaaggaa ccctagcaac
    12541 gctgcttccg attatttttc atctacaagg cgtttctcct ctcatctttg gacttttggc
    12601 tgttatcggc cataccttcc ctatatttgc aggatttaaa ggtggtaagg ctgtcgcaac
    12661 cagtgctgga gtgattttcg gatttgcgcc tatcttctgt ctctaccttg cgattatctt
    12721 ctttggagct ctctatcttg gcagtatgat ttcactgtct agtgtcacag catcgatcgc
    12781 ggctgttatc ggggttctgc tctttccact ttttggtttt atcctgagta actatgactc
    12841 tctcttcatc gctattatct tagcacttgc tagtttgatt atcattcgtc ataaggacaa
    12901 tatagctcgt atcaaaaata aaactgaaaa tttggtccct tggggattga acctaaccca
    12961 tcaagatcct aaaaaataaa acgccagttc tgtactgccc cccaaaagtt agacaattaa
    13021 tttatccaaa ggatttagtt ctgtactgca caggactaag tccttttagt tttaccttaa
    13081 ttcgtttatt gttgtagtaa tcaatatagt ctacaatagc ttgttccaat tgattaagtg
    13141 atttaaatgt tttctcatag ccataaattt cagaatccca aagaaggact ccatcatacc
    13201 gttgtcttgg ctgtttccct tgcgtgacat ggatgcttga attcccttac tctctaagaa
    13261 ccgatgataa gaatcgtgtt gatattgcca gccttgatca ctatggagaa tcgtattctc
    13321 gtagtacttc tctgtgaatg cctgttccaa cattgtttgt acttgttcta agttgggtga
    13381 agttgaaaga ttataggcga taatttcgct gttaaag
//
LOCUS       DAVHSH010000048        13304 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000048 DAVHSH010000000
VERSION     DAVHSH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.049"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(1..289)
                     /locus_tag="VVR08_001609"
                     /pseudo
     CDS             complement(1..289)
                     /locus_tag="VVR08_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(351..800)
                     /locus_tag="VVR08_001610"
     CDS             complement(351..800)
                     /locus_tag="VVR08_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6075496.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(802..1560)
                     /locus_tag="VVR08_001611"
     CDS             complement(802..1560)
                     /locus_tag="VVR08_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6075497.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1675..3654)
                     /gene="pknB"
                     /locus_tag="VVR08_001612"
     CDS             complement(1675..3654)
                     /gene="pknB"
                     /locus_tag="VVR08_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU6075498.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3651..4391)
                     /locus_tag="VVR08_001613"
     CDS             complement(3651..4391)
                     /locus_tag="VVR08_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU6075499.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4406..5719)
                     /gene="rsmB"
                     /locus_tag="VVR08_001614"
     CDS             complement(4406..5719)
                     /gene="rsmB"
                     /locus_tag="VVR08_001614"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU6075500.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5712..6647)
                     /locus_tag="VVR08_001615"
     CDS             complement(5712..6647)
                     /locus_tag="VVR08_001615"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU6075501.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6660..9056)
                     /locus_tag="VVR08_001616"
     CDS             complement(6660..9056)
                     /locus_tag="VVR08_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU6075502.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9122..9436)
                     /locus_tag="VVR08_001617"
     CDS             complement(9122..9436)
                     /locus_tag="VVR08_001617"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU6075503.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9461..10087)
                     /gene="gmk"
                     /locus_tag="VVR08_001618"
     CDS             complement(9461..10087)
                     /gene="gmk"
                     /locus_tag="VVR08_001618"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU6075504.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10217..11830)
                     /locus_tag="VVR08_001619"
     CDS             complement(10217..11830)
                     /locus_tag="VVR08_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU6075505.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12174..>13304)
                     /locus_tag="VVR08_001620"
     CDS             complement(12174..>13304)
                     /locus_tag="VVR08_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU6075506.1"
                     /translation="SYVNPDSSIFDRTSSWLKNLDLDDVQLILPNIDFKVVNLYFRNY
                     SFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNMLIFLPLVDDIDIEKVIEI
                     LNNQTLYYNWREEFRRIIKIVLDNMDVIDKDSLKSKIIGIVNKHLNEILEKNFSLYNS
                     VYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIKNIIEYSDLICHLFKYFE
                     KDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQNKIYHYLIKRINDKRVEG
                     VKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLYPEVDWTWFHDRSDDVIH
                     RLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILKK"
BASE COUNT         3636 a         3072 c         2529 g         4067 t
ORIGIN      
        1 gatatccaaa gaaacaattc tcccttgact tgtgacaatc gcttgagtct tcatagcgtg
       61 aaatttcttt ttaccagaat gattcgctaa ttcttttttt agggcgattg atttttactt
      121 tcgtcgcatc aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaacac
      181 cactttgaac aagagttact tcaacccatt ggctccgacg gagtaagttg ctttcgtgga
      241 taccaaaatc agccgcaatt tcttcataag ttcgatattc tcgcacatat agaaagcgtt
      301 gttaatttat ttatctcatt tttcagaaaa ttcttttatt tctgtaaagt ctacgatact
      361 cgatgtgttt ttatataatg atacagtctg agaatcactg ttccgctagc cattccaata
      421 gagattacca gagccaacat gacaaccaag gtcgcacttg ccagtgcttt attatagtcc
      481 cctgtcacaa aaaaggcagt tgttcggtag gagagataac ctggaaccag cggtgccaaa
      541 atggccaaga taaagaccac agcaggtgtc ttataaagaa tacttaaaat ctggctgaca
      601 caagaaccaa taatggctgc aatgaaggta gctacaatga cattggtcgg ttccttgagc
      661 aagagataga ttagccagac agtcatgccc aaaatccctc caggcaagag catagaccgt
      721 tgcacattga gtacgattaa aaaagtgata atggcaagaa aacttgctac tgcttgtaat
      781 aaaaaggttg ttagtgtcat attagttcat caataccaag gcgacagaag ttcctgcccc
      841 taaagcgagg gtaatgagca gggattcaaa catcttactc ataccagagt ttatgtggtt
      901 ggtcataata tcacggaccg cattggtcaa ggcaatacct ggtacaaacg gcatgaccgc
      961 accagctata atcaaatctg ccgttgaagg aaaacctgtg tagcgagccc aaaactgggc
     1021 aattatccca aagacaaagg ctccagcaaa ggctgtcaca aagggaattc ggataaattt
     1081 ttccacatag agggaaaagg caaaaccaaa taaggtcgcc actcctgccc caagtgcgtc
     1141 gtagatattt ccgctaaaca taactgaaaa gaaaggagca ctaaaggtcg cagccagagt
     1201 tacctgcaac ttagtatagg gaaggggttg agcttgcaag gccgtcaatt gcttaaaggc
     1261 tgtttctaag tcaatctgcc ccccaactag ctgacgagaa atctggttca catcgcagac
     1321 tttttcgatg ttataagaag aggaggtcac gcgcttcatg cgcgaaatat tggtattttc
     1381 aatagagaaa aagatagcgg caggcatggc aaggacattg caatccacaa tcccctgcga
     1441 atgcgcgatt cgaatcatgg tatcttctac acgatggatt tctgagccac ttttaaggag
     1501 aatagtcccc gctagcataa tcacatcaat gacggcattt aattcttttg attcttccat
     1561 gctttcctcc ttttatcaac tccctctatt ctatcacaaa tccggactca aaaaaaatct
     1621 ttgccatgaa atcatgacaa agattgatta ctcattttga ttatccatct gcttttaagg
     1681 agtagctgaa gttgttttag gtttgtagat tgaaatcttg actctagtct tattgaggtc
     1741 taccttttca cctgctctag gactttgttc aacaaccatg ccttctgcac tacctgcagg
     1801 cgctgtcgtc acttctacaa cttctatatt agcttcctta atcccaacaa tttgaatcaa
     1861 attgttctta gtaaactcca agctggaacc aatgtaactc ggcatggcaa cacttgtaac
     1921 ttttttagct actgtcaaga caatttgagt aggtttactc acatcataag tcgttccggc
     1981 acctggactt tgtttcataa tcgttcctgg ttcgctttcg ctggactctt cttcctctat
     2041 cttaatcaaa ttctcaggaa ccttcttctg cttgagttct gagattactt ctgtagagtt
     2101 ccgtccaata tagttcccta attgaatcgt cgtagctttt ttagctactg tcaaaacaat
     2161 ttgagttgcc ttgctcaagt cataggtcgt accttctggt agactttgct tcaggaccgt
     2221 tccagcctca ctctcattcg actcttcttc ctcaatttta atcaaattat ctggaacttt
     2281 tttctctttt aattccgcga taacatcaga agatttccgg ccgacataat tactaatttg
     2341 gaaggattgt ttgcctgatg agacaaccag attgattttc gttccttctt ttcgaccagt
     2401 tccagcgcca ggatctgtac ggataatccg cccttcttcc accttttcac tagcctctgt
     2461 cttctcctca ccaatctcaa aattggcttt tttgagcgtt gccttggcct ctgcaactgt
     2521 ctgacctgcc acatctggaa tggcaatggt tgcaggagtt ctggatagta tccaaataag
     2581 agaagctgcc accaatacaa ggctggccaa caaaatcagg taacgcatct taaatctatg
     2641 ttttttcggt gcttgtggtt ggtaagtttc ctctgtcaca gcctggcttg ggtttttgat
     2701 tgatttgtgt tctgtctgcg cttgaacctt aggaatagat gtcaaggtac tctgagaaac
     2761 cttcggcaag gtcttggtat ctgccttgct cgtttcatca aagattaact tactttcatt
     2821 tctacgattg taggacaagc tactagacaa gtccacatac atctctgaaa ccgagcggta
     2881 gcgattggtc aactttttag cagttgcctt gataataaca ttttctaaag cctgaggtac
     2941 agatggattt tctgcaataa cggacggcag gggtttctgg aaatgctgga gggcaatggt
     3001 caccgcgcta tccccgtcat aagggatatg gcctgtcaac atctcataga aaataatccc
     3061 catggcatag atatcactct gcacagtcgc cttagaacca cgcgcctgct ctggtgacaa
     3121 gtaatgaact gagcccaaca tcgagttagt ctgggtcaga cttgtctctg caaaggctac
     3181 agcaatccca aagtctgtga ccttggccgt cccatctggt gtcaaaagga tattttgagg
     3241 tttcaagtcc ctgtgaacaa ttcctcgagt atgggccaag cgcatagcca agagaatttg
     3301 tcccatgata cggactgctt cttcattaga aagaggataa tgttccttga tatagcgttt
     3361 gaggtctagt ccagcaacat actccattgc aagatactgt tgaccgtctt cctcaccaat
     3421 atctgttatc cgaacgatat gaggatggtc tagatctgcc atagctctcg cttcacgctg
     3481 aaaacgagct acagctatcg ggtccgtctg gtagttggtc ctcagaacct tcactgccac
     3541 ttcttcccca tctaagatta agtctttggc taggtagaca tccgccatac ctcctcgacc
     3601 aatctgtttg acaatccgat agcgtccggc aaaaatcttg ccgatttgga tcattctgca
     3661 tcctcctcgt tcatagaaac aagggcaacc gtaatgttgt ctaaacctcc tgcattgtta
     3721 gcaaaacgaa caagtgtctc cgttttatct gctaaaggaa tatcactggt tacaatatca
     3781 cgaatctcac tgcctgaaat catgttggtc aagccgtcac tattgagcaa gagatagtca
     3841 cctgactcaa ggataactgt cccaaaatca ggctgaattt catctttttg cccaatagac
     3901 tgggtgataa tatttttttg cggatgagct tctgcctctt ctggtgtcaa ttgaccagcc
     3961 ttgagcaatt cattaaccaa agaatgatca ctcgtcaact gatggtattc ttctccacga
     4021 atcaagccga tacgcgaatc accaatatga gcatagatag cctgattatc aataatagca
     4081 aggacttcca aagtagttcc catgcctctg taagcttcat cctgaccaag ctggtgaatc
     4141 ttttgatttt caatttctag gtaatgggcg aaccattcac gcacttcatt gactgtatcg
     4201 atctgagtat caacccaagc tacacccagg tctgtgaccg ccatttcact agcgatattc
     4261 cctgcgcgat gacctcccat cccatcagct aaaataatca tggtacgtcc agctctattg
     4321 acatagtggt tgacatagtc ttggttattt gttcgtttct gaccaacatc tgttaataat
     4381 gaaatttcca tgtgtcagtt ccttcctaat ccgatatctt gcgaaattga ctgatgaaga
     4441 atccatcact tccatacaat tcaggtgtaa tgaggataca gccgtctttc atgatatcct
     4501 tacattcatg ttctagtttt acctgctcga actcgggatg actctctaaa aaggccttaa
     4561 cgacttgaaa attctcctct gagacgatag tgcaggtgct ataagttatt ataccacctt
     4621 tgcctagtat ttgacaaaca ctacctaata tttctaactg aatttcctgc aaggacgcga
     4681 aatctgccgt ttctttattg tatttgatat ctggttttcg gcgcaaaaga ccgattcctg
     4741 aacaaggagc atccaccaaa atcttatcaa aggaatcctg gtcaaaaaac tcatgcacct
     4801 ttctggcatc caatttttga gtttgaaccc gatcttcaac tcccagacgt tgggcatttt
     4861 cttgaattaa atccaacttg tggtcgtaca agtccagagc agtaacctga cctgtcgtaa
     4921 gataagaggc tatatgggct gttttcccac ctggagccgc acaggcatca agcactcgct
     4981 catcaccttg taaatcaagc gtcggagcaa ccagctgact ggactcgtct tggatggtaa
     5041 tggctccatc cgcaaacaaa ttatgccctg caaaatgccc ttgctcctta accagaccag
     5101 tggttgctaa aagggaatta ttcgcctcca acaaggcttg gatttcctct tttcgactta
     5161 ggtctgttac acgaatactg gctttgtttc gcactaacag gctttcaaag atggcttttg
     5221 ctctctcctc tccgtattct tccttgagtt tggcaactag ccaaactggg agagaatagg
     5281 caatggagtc acgcttgttt tttcgcttga tgctagcaat atctggccag ccttcacgca
     5341 agatacggcg aaggacagcg ttgaccaatt tttcactgcc ttttttacgg agtttggcca
     5401 attccactgc ttcattgacc acagcatgat ctggaatctt gtccaaatag cggagttggt
     5461 aggcactcat gagaagaagg acatagagcc agctgtctaa ctggtctctg tcttcgataa
     5521 agtgggatag gtaccattcc agagtcagtt tacgggctac cgttccatag actagctcgg
     5581 tcactaagcc cttgtctgct gcagagagct gactcccctt gaggtgttta tttaaggcaa
     5641 tatttgaata tgcttgattc acaaaaacat cctctagcac tgctagagct aaacttctag
     5701 ccgtttctac tttagtcacc aaatcgttct cctacagtca atgtacgtcc aaccccgttg
     5761 aggaaggaag caatgtccat cttaggctta ccagctggct gcacttgttt gagggataga
     5821 gccccttcag ccgttgcgac aatcaattct ttcttgcaga tagagagaat ctcacctgga
     5881 tttccctgac cttctactgg tagggcttca taaatcttaa agcggtcgcc cttaaggaaa
     5941 gtatgggcaa caggccaggg gttcattcca cgaatttggt taaagagttg acgattggtt
     6001 ttgttccagt ccagtttttc ttcctctggc tttatatttg gagagaaggt aacctgactc
     6061 gtatcctgcg gttcaggttt gatatcacca gcaatatagg caggcagagt gtccaaaagc
     6121 aaatcacgac caactagcgc caatttttca aacaaggtgc caacattgtc ctcatctgtg
     6181 atcggaatgc tgcgacgaga aatcatatct cctgcatcca tttccttaac catttccatg
     6241 atggtcacac cagcttcctc atccccttga atcaaggcat aatggatagg cgcaccacca
     6301 cggtgtctag gaaggaggga ggcatgaacg ttgacagcaa agtccatgct atcaaggagt
     6361 ttgcttggga gaaactgccc aaaagcagca gtcacaattc catctgctcc tagcttcata
     6421 agttcttcca tctctggact tccagataat ttttcaggtt ggtagataga tagtcctgct
     6481 tccttggcag cctgcttgac tggggtttct tggataactt ttttacgacc aacagcacgg
     6541 tctggctggg tcacaacggc tagaatttcg taacggtcat ctgtcaaaag tccttttaag
     6601 actgttgctg aaaagtcggg ggtccccata aagattagtt ttgtcatatc ttctccttct
     6661 tataaaaatt gctgcggctc atggtcaatg ctgagacgga gctcactatt ttcccgttct
     6721 tgagtcaagg ctaaaacctg gttgagggtc ggccccagct catcttctaa acggtattta
     6781 attaaaatct ggtaatgata gaggttgtgg gtacgggcaa tcggttttgg cgttggcccc
     6841 agaatgggac tggtctctga caagcctgac cgcaaaatgt tcatgacttc ataggcacgt
     6901 ttgaaaacct cttcttcttt cttgtgagaa agggtaatac caatcgtgaa atagtaaggt
     6961 ggatagccga gttgtcgtct gattcccatt tcataggcat aaaagccttc gtaatcttga
     7021 tccttggcaa atcgaatagc atagtgctgc gaattgtagg actgtatcaa gacttgacct
     7081 gctttttcag cccgacctgc tcgacctgcc acctgagtca agagctggaa ggttctctca
     7141 gaagaacgga aatcaggcag attcaaggcc gtatccgcat ttagaactcc gactagggta
     7201 acattgggaa aatccaaacc ctttgcaatc atctgagtac caagtaaaat atccgcttcc
     7261 cctcgcccaa actggtcaag caaggcttgg tgactgcctt tctttcgagt cgtatccaca
     7321 tccatcctca aaatgcgagc ttggggaaag agttctgcta gctcatcata agccttctga
     7381 gttcccgtcc catagtaacg aatactgcgg ctcttacagt taggacagac ctgaggaata
     7441 tccttcgaga aaccacaata atggcagttc atagtcttgg tatccatatg caaggtcaga
     7501 gaaatatcgc agttgggaca agtatccacc gtcccacact cccgacacat gacaaagcta
     7561 gaataaccac ggcgattgag catgagaacc acctgctctt ttttaaccag acggtcttgg
     7621 atagcctcta gcaaaggagg cgtaaagttt gacgtctcat tttgtccgat atagtctcga
     7681 aagtcaatca cttgaacctc agggattgta gccaaaggat tggcacgttg ggttagacgt
     7741 aagtgttgat agacgccttt gccagcacgt gcccggctct ctaagctcgg cgttgcagat
     7801 ccaagtacca gagttgcttg attatactga gcccgtaaaa tagctacctc tctggcatgg
     7861 taacggggat tgctgtcctg cttataagcc gcttcatgct cttcatcaat aatcatgaca
     7921 cccagatttt tcagaggagc aaagatagca gatctggcac caacaacaac ttgggcatcg
     7981 ccacgctcca ccttgcgcca ttcatcatac ttttcaccat tggataatcc tgagtgaaga
     8041 atggctacct tgtccccaaa acgtgctata aaacgctcgg tcatctgagg agtcaaggaa
     8101 atctcaggta ccagcaaaat agctgtcttg cccttatcca gggcaccttg gataatctgc
     8161 aagtaaacct cggtcttccc acttcctgta atcccttgaa gtagaaaggg aggttgagaa
     8221 ctgccaatag aactcacaac cgcatcacgc gcctgtcttt gttctggatt taactccaaa
     8281 ggtctacttg cttcaattcc ttcaaaataa gcagccgagc gtcgaacttc cttttggact
     8341 atggtaacag caccttgatc cacaaagaag ttgacttgct ctcgcgagta ggactctaac
     8401 aagctagcca aggaagcgct ctctggatga gacagcagat aatctctcag ttccaacttt
     8461 ttcttggcac gtgtagaaat ctcaacacct tctaattggg catggtcaac ctcataccaa
     8521 gactgggtct tgaccttctt ttgatcgact gcctgatatt ccagaccaag caggcctttt
     8581 ctagtcaaac gcatcatttc agcttgctta cctaaatcca gagaagaaaa ggctagcgaa
     8641 tcttctgaac caaacaggcg cactcgttct tcctgactca agccttccag aggatagaga
     8701 atcttgtcat agctagaatt cagaaatcct ggaagcatgg ccttgaggat agagattttg
     8761 taggagaaga cagatttgcg taactcctca gccagccaga gttgttctgg cgtgagaaca
     8821 ggagaaaaat ccagcacctc tgcaatatct tttaaatctt gctccatctc ttctccatct
     8881 gattgggact ccaaaccaag aacaatccct tgaatcaggc gattaccctt accaaaaggt
     8941 acatgaaccc gcatcccaac ttccagcatt ccctcaaatt cctccggaat cctgtaacta
     9001 tagggctggt ccgtctgcat caagggcaca tctacgataa tcttagctag ggccatcttc
     9061 tcacctcctc cttgtcagta cattcttgca atagaaaaaa taagattgag tccccccaac
     9121 cttaaatttt ttcaccatct tctttttctt tagcaatttg ctctttgatt ttcttttctt
     9181 cttcttcttt gcggcgtttt tcttcttcga tacggcgacg cactgcttca cgttttcctt
     9241 ctggatctgg gtgaattgta acgtttcctg attcgatttc ttctaaagcg cgaagagttg
     9301 atttttcaga cttgaaacct tgagttgctg gggcacctgc ttccaattcg tgggcacgtt
     9361 ttgcttccaa gattacgagt gaatattttg aaggaacctt gtcgagcaag gtatcaatag
     9421 agggttttaa catcatttgc ttgtacctat tttctaaatt ttatcgggta gttggagatt
     9481 ttggtaacat ctcctgatag tgaccaatga cacgatccac acagaaatgt tctgcttcaa
     9541 tcacacattt gacacgttca gcagctaggg gcacctgatc gttgacaatg gcataatcat
     9601 actcacgcat gagggcaatt tcttccttgg ccttttcgat tcgttgggca atcacttctg
     9661 cactatctgt tccacgacct accaagcgat cttgcaattc atccaaatct ggtggtgtca
     9721 ggaagataaa gacagcatct ggaacctttt tcttgacctg aagagcaccc tgaacttcaa
     9781 tttcaaggaa aacatcgatt cccttgtcca aggtttcatt gacataggtc agaggagttc
     9841 catagtagtt accgacatat tctgcgtatt ccaacatctg tccttgacga atcagctctt
     9901 caaattcttc acgagtacgg aagaaatagt caacaccgtc cacttctcca ggacgttgtg
     9961 cgcgtgtcgt catcgataca gagtattgaa attggttttc agaactctca aaaatctctc
    10021 ttctaaccgt tccttttcca acccctgaag gaccagaaaa aacgattagt aagcctcggt
    10081 ctgccattgt gtctcctttt agtcaatctg tgaaataaca tttctctaga ataatggcaa
    10141 aaagccagat tatcctttac agtctttcta tctagtgtaa caaaaaagca gtaatttttc
    10201 aactgctctt tcttatttat ttagcataat ctactgcacg aagctcgcga atcacggtta
    10261 ccttgatatt tcctggataa tcgagattgt tttcaatttt cttacgaact ttgtgagcca
    10321 agattgtgac tttgtcgtcc ttgatttttc ctggattgac catgatacga atttcacgtc
    10381 ctgcttgaag ggcaaagcta gtttgcactc cttcaaagcc gttagcaatt tcttccaaat
    10441 catggagacg cttgatgtag ctttcaagag actcactacg agcacctgga cgggctgcgc
    10501 tcaaggcatc tgctgcagcg acgataactg ctatcacgct ctcagcttca acatctccgt
    10561 ggtgactagc aatcgtattc accacaactg ggggttcctt gtacttacgg gccaattcca
    10621 taccgatttc aacgtggcta ccttcaacct catggtcaat ggctttcccg atatcgtgaa
    10681 ggaatccagc acgacgggca agagccgcat tttcaccaag ttcgctcgcc atgataccag
    10741 ccaacttagc aacctcaatc gaatggcgca aaacattttg tccatatgaa gtacggaact
    10801 gcaaacgtcc cataatcttc atcaagtctg gatgaaggtt tggcgcacca atttcatagg
    10861 cagcagcctc accgtattca cgaatcttat tgtcaatctc ttgacggttt ttctcaacca
    10921 actcttcgat acgagctgga tgtatacgac catctttgag caacatttcc atagtcatac
    10981 gggcaatctc acgacgaatc ggatcaaatc ctgacaaggt caccacttct ggtgtatcgt
    11041 cgataatcac atcgacccct gtcaaacttt caaaggtacg aatgttacga ccttcacgac
    11101 caataatgcg tcccttcata gtatcgtctg gcagatgaac tgttgagttt gttgactccg
    11161 ctacatattc accagcgata cgttgcatag cttgaaccaa gatgtcctta gccattttgt
    11221 cagaacgttc cttgacctct tgctcagctt cgcgaatgcg actggcaatc tccctggtca
    11281 agttttcctc tgtctgagcc aagataatat ctcgtgcttc tgcctgagac agagcaccaa
    11341 tacgctctag ttctgcttct ttttgtcttt cgacttcctc taattgctct tcacgcgcat
    11401 caaggttttt cgctctatca gaaatacttt gttctttttg ttcaagtgtt tgttctttac
    11461 tcgtcaaatt gtcgtcctta cggtcaaggc tagtagctct ctctgtcaaa cgactttcga
    11521 tttgtttgag ttcttgacgt tctgatttga attcagcgtc cacttcttca cggtattttc
    11581 tggcttcttc tttggcctcc aatagtgctt cttttttaag agacttgctt tcacgtttag
    11641 cttcattaac aagtaaatcc gcttcacgct cagcttgtcc acgtaaatta gttgcttctt
    11701 gttcagcatt taaaagcatc aactccgcag cttcctgaga tgatttcatc ttagctgaga
    11761 tgctgacata tccaatgact aaaccaatga tgacggcaaa aacagcaatc gcaagcgaca
    11821 tgatttccat gtttttacct cattttattg ttattccgaa tgacatacat tcttttacat
    11881 tctaccataa aaaagtgatt ttcacaaacc taaaatagaa tatgttttgg ggaatttagt
    11941 ctgaatttta ggattacact tccttggttt tttaaggaga taagtcagtg tcgctatcaa
    12001 aaagttccac cgaatttcta caactatgga ttttctattg ttgtgccaaa tagtgttcca
    12061 ctagattcaa acattttgct ttcaagtctt tgaaaattca ctttaggaaa ttacagctta
    12121 tcttcaagat caaatttgtc ataaattaac tttttttatt tagttgtatc aatttatttc
    12181 ttaagtatta atttatcctc atcgaaagct tttaaaatat actcattaat caatttatta
    12241 tcttcttcat tttttgaaaa ataagtttta atattattgg gagttctatg ttctagtaga
    12301 cgatggataa catcatcact tctatcatgg aaccaggtcc aatctacttc aggataaagt
    12361 cctcgaatat cttcttcaat atcttttaaa atctcaaaat cagaaaaata tccttttcta
    12421 cttaagttgt ataaatctga tacagacttt tctcttgggt ctgggaaagt tttaaccccc
    12481 tcaactcttt tatcattaat tcttttaatc aaataatggt agattttatt ttgtatctga
    12541 ggaaaatcat agacattata actcatcaaa tcaattactt tatggtaaat aatattttct
    12601 gattcttcat aaacttttag agtatctaga atgtcatctt taatatcctt ttcgaaatac
    12661 ttaaataagt ggcatatcaa gtcagaatat tctatgatat tttttatatc atcattttta
    12721 tattttattc ttaaaatatc tgtattaaat ttttcgagta ctattattgc agtttcctga
    12781 tcagttgagc agtattctag taactgtgaa tagagtggat acactgaatt atataaagaa
    12841 aaatttttct ccaaaatttc atttaaatgt ttatttacaa tcccaattat cttagatttc
    12901 aatgaatctt tatcaataac atccatatta tcgaggacaa ttttaataat tctcctaaat
    12961 tcctctctcc aattataata cagtgtttga ttatttaaaa tttctattac tttttctatg
    13021 tcaatatcat caacaagagg aagaaaaatt agcatatttt taagctctcg aagattttca
    13081 tcttcagtaa tttcaagtct ttcttgaaga taagtaattc gattcaacaa gtagtctttc
    13141 gcttcctcag taacttttat tttaccaaat gaatagtttc taaaatataa atttacaacc
    13201 ttaaaatcta tattcggaag aattaattga acatcatcca aatcaagatt tttaagccaa
    13261 gaagatgttc tatcgaaaat acttgagtca ggatttacat atga
//
LOCUS       DAVHSH010000049        12688 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000049 DAVHSH010000000
VERSION     DAVHSH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.050"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..435
                     /locus_tag="VVR08_001621"
     CDS             <1..435
                     /locus_tag="VVR08_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6075507.1"
                     /translation="SNTLIYLKALNTLYNFYSLVGREQEYEANYSHLMELYQTKNFEH
                     QEFLFGYIRVRYNYAHYLVSKEKYNEAIQEALETIELCKQRQTSYQLAPLLILVGNAG
                     AKFLDREQVKNYYIEARELCKIYNNPLMLMKIENYLKELDTV"
     gene            818..1438
                     /locus_tag="VVR08_001622"
     CDS             818..1438
                     /locus_tag="VVR08_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075508.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTSLATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            1524..1967
                     /gene="tsaE"
                     /locus_tag="VVR08_001623"
     CDS             1524..1967
                     /gene="tsaE"
                     /locus_tag="VVR08_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU6075509.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            1957..2475
                     /locus_tag="VVR08_001624"
     CDS             1957..2475
                     /locus_tag="VVR08_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6075510.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLFAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2483..3499
                     /locus_tag="VVR08_001625"
     CDS             2483..3499
                     /locus_tag="VVR08_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU6075511.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            3583..4839
                     /locus_tag="VVR08_001626"
     CDS             3583..4839
                     /locus_tag="VVR08_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU6075512.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            4894..6060
                     /gene="recA"
                     /locus_tag="VVR08_001627"
     CDS             4894..6060
                     /gene="recA"
                     /locus_tag="VVR08_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU6075513.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6367..7737
                     /locus_tag="VVR08_001628"
     CDS             6367..7737
                     /locus_tag="VVR08_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6075514.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8113..9069
                     /gene="lytA"
                     /locus_tag="VVR08_001629"
     CDS             8113..9069
                     /gene="lytA"
                     /locus_tag="VVR08_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU6075515.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9427..9588
                     /locus_tag="VVR08_001630"
     CDS             9427..9588
                     /locus_tag="VVR08_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075516.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            9575..9781
                     /locus_tag="VVR08_001631"
     CDS             9575..9781
                     /locus_tag="VVR08_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075517.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            9827..10321
                     /locus_tag="VVR08_001632"
     CDS             9827..10321
                     /locus_tag="VVR08_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075518.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            10314..10739
                     /locus_tag="VVR08_001633"
     CDS             10314..10739
                     /locus_tag="VVR08_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075519.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            11147..11941
                     /locus_tag="VVR08_001634"
     CDS             11147..11941
                     /locus_tag="VVR08_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075520.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            11945..12142
                     /locus_tag="VVR08_001635"
     CDS             11945..12142
                     /locus_tag="VVR08_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075521.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            12132..12683
                     /locus_tag="VVR08_001636"
     CDS             12132..12683
                     /locus_tag="VVR08_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075522.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
BASE COUNT         4005 a         2040 c         2769 g         3874 t
ORIGIN      
        1 tcaaatactc tgatttattt aaaggcattg aatactctat ataatttcta ttccttagtg
       61 ggtcgtgaac aagaatatga ggcaaactac tctcatttga tggagttata tcagacaaaa
      121 aattttgagc atcaagagtt tttatttggc tacatcagag ttcgttacaa ctacgctcac
      181 tacctagtat caaaggaaaa atataatgaa gccatccaag aagctcttga aacgattgaa
      241 ctctgtaaac aaagacagac aagctaccaa ttggctcctc tacttattct tgtaggaaat
      301 gctggagcca aatttctaga cagagaacaa gtcaaaaatt attatataga agcaagagag
      361 ctatgcaaga tttataacaa tcctttaatg ctgatgaaga tagaaaatta tttgaaggaa
      421 ctagatactg tttagttaat cttgacatta tagtttttct gaaacgttaa ataacctgta
      481 aggctgatag ttagattaat actatcagcc ttataattat gtgactctga gtccgtctcg
      541 ctccgtgagg tgcgagacaa aacaaccacc cgtttgacgg attttcatga tttcaaatct
      601 atattcttcg aaaatctctt caaatcacgt cagctctatc tgcaatctca aaacactgtt
      661 ttgagcaacc tgtggctagc tacctagttt gatctttgat tttcattgag tattagtctc
      721 tagtgtttgt ttagcgtctt aaagagacat ttgagaagat tagaaacagt tctctctttt
      781 ctcctagtat aatgattggt aggaagggag agagaagatg aaatcaatga gaatcttatt
      841 tttgttagct ttaattcaaa tcagtttgag tagctgtttc ctatggaagg aatgcatctt
      901 gtcctttaaa caaagtacag cttttttcat cggaagcatg gttttcgttt caggaatctg
      961 tgctggagta aattatcttt atacccgtaa gcaagaagtc catagtgtcc tagccagtaa
     1021 gaagtcggtg aagctttttt acagtatgtt actcttaatt aatttgttag gagctgttct
     1081 tgttttgtca gataacttgt tcatcaaaaa tacgctgcag caagaattag ttgacttttt
     1141 attgccatcc ttctttttcc tatttgggct agatttgctg atttttttac ccttgaaaaa
     1201 atacgtgcgc gattttcttg ctatgctaga cagaaaaaag acagtgttgg tgactagttt
     1261 agcaacactt cttttcttaa gaaatccaat gaccattgtc tcacttctga tttatattgg
     1321 actgggcttg ttttttgcag cctatcttgt cccaaattcg gttaagaagg aagtttcctt
     1381 ttatggtcat attttccgag atcttgtatt ggtcattgtt acgctcattt tcttttagag
     1441 aaagcctgtt ttttatggat gttatgatga taagtttagt aggaaaatag acacaaaaga
     1501 aaagtttttg gtataataag agtatgtaca caaaaaatga agaagagttg caagccttag
     1561 gggagcgttt gggccatcta ttagcaaaga atgatgtttt aatcttaact ggagaactgg
     1621 gtgcaggtaa aacgaccttt actaaaggac ttgcaaaagg attacagatt tctcaaatga
     1681 ttaaaagtcc cacctatact atcgtgagag agtatgaagg tcgacttcca ctttatcacc
     1741 tagatgttta tcgtattgaa ggagatgctg attctatcga cttggatgag tttatctttg
     1801 gtggtggcgt gactgttatt gagtggggaa atctcttagg agatgccttg ccagatgctt
     1861 atttagaatt ggaaattcta aaagaagcag atggacgccg tttaaatttt caggcaaagg
     1921 gtttgcgtgc tgagaaattg ttagaggagc ttcaatatgg agtatgaatt gctcattagg
     1981 gaagcagagc ccaaagatgc agctgaatta gtggcctttt taaatcgtgt gagtttggag
     2041 acagacttta ccagcctaga cggagatggt attctcttga ctagtgagga gatggaaata
     2101 ttcctcaaca agcaagctag ttcggacaat cagataacct tatttgcatt cttaaatggc
     2161 aaaattgctg gtattgtaaa tattacagct gatcagcgta agagagtccg tcatattgga
     2221 gatctcttca ttgtgattgg aaaaagatat tggaataatg gcttgggaag tttgttgcta
     2281 gaagaagcga tagagtgggc acaagcaagt ggcattctgc gtcgtctcca actgactgtc
     2341 caaactcgta atcaagcagc agtccatctt tatcaaaagc atggctttgt cattgaaggt
     2401 agccaagagc gtggggcata tatagaagaa gggaaattta tcgatgttta cttgatgggt
     2461 aaactgatag gttagtagaa atatggttaa aaaaattatt ggaatggtgc tagctttact
     2521 ttctgtaact gtagtaggag taggtgtttt tgcttatact atttatcaac aagggacaga
     2581 aaccttagct aaaacctata aaaaaatcgg cgaagaaacc aaggttattg aagcgactga
     2641 acctctaacc attctgttaa tgggagtgga caccggaaat gttgaacgaa ctgaaacttg
     2701 ggtcggtaga agtgatagca tgatcttgat gacagtgaat cctaaaacga aaaaaacaac
     2761 aatgatgagt ttagagcggg atattctgac gcgcattgaa tcagggaatg gtcaggctca
     2821 tgaagcgaaa ctgaactcag catatgcaga tggtggagca gagcttgcta tagaaaccat
     2881 tcaaaaaatg atgaatatcc atattgatcg ctatgtgatg gtcaatatga gagggttgca
     2941 aaaactagtg gatgcagtag gaggtattac agtcaataat atcctaggtt tcccaatttc
     3001 tatcagtgac caagaagaat ttaatactat ttctatcggt gttggggagc aacatattgg
     3061 gggagaagaa gccctagtct atgcacgaat gcgttaccaa gatcctgagg gggattatgg
     3121 tcgtcaaaaa cgtcaacgtg aagttattca aaaagtcatg gaaaaagctc tcagtttaaa
     3181 tagcattggt cattatcaag agattctaaa agctttgagt gacaatatgc agaccaatat
     3241 tgatttgtct gcaaaaagta tccctaactt gctaggctat aaagattcat ttaaaaccat
     3301 tgaaactcag cagttgcagg gtgaaggaga gatacttcaa ggtgtttctt accagattgt
     3361 ttcgagagca catatgttgg aaatgcaaaa tctactccga cgttctttgg gacaagaaga
     3421 agttactcag cttgaaacca atgcggtttt atttgaagat ttatttggca gagcacctgt
     3481 tggtgatgaa gataattaac ttttgataca aataaaaaat caatcgtagg aaaattcctg
     3541 cgattttttc aaaaaaatac gaatagatag gtaggaggaa acatgaaagc agaaatcatt
     3601 gctgttggaa cagagatttt gacaggacag attgtcaaca ccaatgccca gtttttgtcg
     3661 gaaaaactag ctgagattgg ggtagatgta tattttcaga cggctgtagg agacaatgaa
     3721 gttcgtctct tgtctttgct tgagattgcc agtcaacgta gcagtctggt gattttgaca
     3781 ggcggtttgg ggccaactga ggacgaccta accaaacaaa ccctagctaa atttttaggg
     3841 aaagcattag tctttgatcc tcaggctcag gagaagttgg atatcttttt tgccctgcga
     3901 ccagactatg cccgaacacc gaataacgaa agacaagctc aaattgtaga aggagcgatt
     3961 ccactgccaa acgaaacagg actggctgtt ggaggaaaat tagaagtaga cggagtgacc
     4021 tatgtcgtcc ttccaggtcc gccaagtgaa ttgaaaccca tggtcttaaa ccaacttcta
     4081 cccaagttga tgacagggag caagctgtat tcccgagttc ttcgtttctt tgggattggc
     4141 gagagccagt tggttacgat tttggctgat ttaattgata atcagatcga tcctaccttg
     4201 gccccttatg ccaagacagg agaagtcact ctacgtctgt caacaaaggc tagcagtcaa
     4261 gaagaggcga atcaagcgct ggatatcttg gaaaatcaaa tcttggactg ccagactttc
     4321 gaaggaattt ctttacgaga cttttgctat ggttatgggg aagaaactag tttagccagc
     4381 attgtggtag aagaactgaa aaggcaaggg aaaaccatcg cggctgcaga gagtttgacg
     4441 gcaggtcttt tccaagctac cgtggcgaat ttttctggag tttcaagtat atttaagggt
     4501 ggttttgtga cctatagctt ggaggaaaaa tcaaggatgt tggatattcc tgccaagaat
     4561 ttggaagaac atggtgtggt gtctgaattt acagctcaga agatggctga gcaggcacga
     4621 agcaagaccc agtctgattt tggaattagt ttgactggag tggcaggacc agatagccta
     4681 gaaggacacc cagttgggac agtcttcata ggcttggcgc aagatcaagg aactgaggtt
     4741 atcaaggtta atattggagg cagaagccga gcagatgtac gtcacattgc ggttatgcat
     4801 gcctttaacc tagttcgcaa ggctttatta agtgactaac ttttgatata atagtagata
     4861 ggtctgagga tcattagaat gtaggagaat agaatggcga aaaaaccaaa aaaattagaa
     4921 gaaatttcaa aaaaatttgg ggcagaacgt gaaaaggcct tgaatgacgc tcttaaattg
     4981 attgagaaag actttggtaa aggatcaatc atgcgtttgg gtgaacgtgc ggagcaaaag
     5041 gtgcaagtga tgagctcagg ttctttagct cttgacattg cccttggctc aggtggttat
     5101 cctaagggac gtatcatcga aatctatggc ccagagtcat ctggtaagac aacggttgcc
     5161 cttcatgcag ttgcacaagc gcaaaaagaa ggtgggattg ctgcctttat cgatgcggaa
     5221 catgcccttg atccagctta tgctgcggcc cttggtgtca atattgacga attgctcttg
     5281 tctcaaccag actcaggaga gcaaggtctt gagattgcgg gaaaattgat tgactcaggt
     5341 gcagttgatc ttgtcgtagt cgactcagtt gctgcccttg ttcctcgtgc ggaaattgat
     5401 ggagatatcg gagatagcca tgttggtttg caggctcgta tgatgagcca ggccatgcgt
     5461 aaacttggcg cctctatcaa taaaaccaaa acaattgcca tttttatcaa ccaattgcgt
     5521 gaaaaagttg gagtgatgtt tggaaatcca gaaacaacac cgggcggacg tgctttgaaa
     5581 ttctatgctt cagtccgctt ggatgttcgt ggtaatacac aaattaaggg aactggtgac
     5641 caaaaagaaa ccaatgtcgg taaagaaact aagattaagg ttgtaaaaaa taaggtagct
     5701 ccaccgttta aggaagccgt agttgaaatt atgtacggag aaggaatttc taagactggt
     5761 gagcttttga agattgcaag cgatttggat attatcaaaa aagcaggggc ttggtattct
     5821 tacaaagatg aaaaaattgg gcaaggttct gagaatgcta agaaatactt ggcagagcac
     5881 ccagaaatct ttgatgaaat tgataagcaa gtccgttcta aatttggctt gattgatgga
     5941 gaagaagttt cagaacaaga tactgaaaac aaaaaagatg agccaaagaa agaagaagca
     6001 gtgaatgaag aagttacgct tgacttaggc gatgaacttg aaatcgaaat tgaagaataa
     6061 gctgttaaag cagtggagaa atccgctact ttttcgattt ttgattcaag tttttagatt
     6121 atatatagta gcttgaaata agatatgaac aactttatta ggaaagtcaa attaatttct
     6181 agaaatgttt tagcagctac agcgtactat tccaaactca accaactata atagatcgaa
     6241 actagaatag tacacatcta cttctaaaac attgttaaaa atcgatttga ctgtccttat
     6301 ttcattccgc tatatataag tttgctgttt cttgtcgctc ctctggaaag ctgatataat
     6361 agctttatga ataaaaaacg aacagtggac ctgatacatg gtccgattct tccctcgctc
     6421 ttaagcttca cctttccaat cttgctatca aatatttttc aacagctcta taacactgct
     6481 gatgtcttga ttgttggacg atttcttggt caagaatcct tagctgcagt aggagcgacg
     6541 acagcgattt ttgacctgat tgtaggtttt acacttggtg ttggcaatgg catggggatt
     6601 gtcattgctc gttattatgg ggctcggaat ttcactaaaa tcaaggaagc agtagcagcc
     6661 acctggattt taggtgctct tttgagcatt ctagttatgt tgctgggctt tcttggcttg
     6721 tatcctctct tgcaatactt agatactcct gcagaaattc ttcctcaatc ttatcaatat
     6781 atttctatga ttgtgacctg tgtaggtgtc agctttgctt ataatctttt tgcaggcttg
     6841 ttgcggtcta ttggtgacag tctagcagcc ctgggatttc tgattttctc tgccttggtt
     6901 aatgtggttc tggatctcta ttttattacg caattgcatc tgggagttca atccgcagga
     6961 cttgctacca ttatttcgca aggtttatca gcggttctct gcttttatta tattcgtaaa
     7021 agtgtgccag aactcttgcc acggtttaaa catttcaaat gggacaaaag cttgtacgcg
     7081 gatctcttgg agcaaggttt ggctatgggc ttgatgagtt caattgtatc tatcggcagt
     7141 gtgattttac agttttctgt taatacattt ggtgcagtga ttattagtgc ccagacggca
     7201 gctcgacgca ttatgacctt tgcccttctt cctatgaccg ctatttctgc atcaatgacg
     7261 acctttgctt ctcagaatct aggagctaag cgacctgacc gcattgttca aggtcttcga
     7321 atcggcagtc gtttaagtat atcctgggca gtttttgttt gtattttcct cttttttgcc
     7381 agtccagcct tggtttcctt cttggctagt tcgacagatg gttacttgat agaaaatgga
     7441 agtctctatc tgcaaatcag ttcagccttt tatcccattt tgagcctctt gttgatttat
     7501 cgcaattgct tgcagggctt ggggcagaag atccttcctc tagtttctag ctttattgaa
     7561 ctaatcggaa aaatcgtttt tgtggttttg attattcctt gggcaggata taagggtgtt
     7621 atcctttgtg aacctcttat ctgggttgcc atgacagttc aactgtactt ctcactattc
     7681 cgtcatccct tgataaaaga aggaaaggca attttggcaa ccaaagtgca atcctagttg
     7741 gatttactga ataaaatcca tttcctctag tgaaaatcga aaaaacttgt gttctcttct
     7801 ttagtttggt gttgaaaata gtttaacaga cttttgactt cttttatatg atataataaa
     7861 gtatagtatt tatgaaaagg acatatagag actgtaaaaa tatacttttg aaaatctttt
     7921 tagtctgggg tgttattgta gatagaatgc agaccttgtc agtcctattt acagtgtcaa
     7981 aatagtgcgt tttgaagttc tatctacaag cctaatcgtg actaagattg tcttctttgt
     8041 aaggtagaaa taaaggagtt tctggttctg gattgtaaaa aatgagttgt tttaattgat
     8101 aaggagtaga atatggaaat taatgtgagt aaattaagaa cagatttgcc tcaagtcggc
     8161 gtgcaaccat ataggcaagt acacgcacac tcaactggga atccgcattc aaccgtacag
     8221 aatgaagcgg attatcactg gcggaaagac ccagaattag gttttttctc gcacattgtt
     8281 gggaacggtt gcatcatgca ggtaggacct gttgataatg gtgcctggga cgttggaggc
     8341 ggttggaatg ctgagaccta tgcagcggtt gaactgattg aaagccattc aaccaaagaa
     8401 gagttcatga cggactaccg cctttatatc gaactcttac gcaatctagc agatgaagca
     8461 ggtttgccga aaacgcttga tacagggagt ttagctggaa ttaaaacgca cgagtattgc
     8521 acgaataacc aaccaaacaa ccactcagac cacgttgacc cttatccata tcttgctaaa
     8581 tggggcatta gccgtgagca gtttaagcat gatattgaga acggcttgac gattgaaaca
     8641 ggctggcaga agaatgacac tggctactgg tacgtacatt cagacggctc ttatccaaaa
     8701 gacaagtttg agaaaatcaa tggcacttgg tactactttg acagttcagg ctatatgctt
     8761 gcagaccgct ggaggaagca cacagacggc aactggtact ggttcgacaa ctcaggcgaa
     8821 atggctacag gctggaagaa aatcgctgat aagtggtact atttcaacga agaaggtgcc
     8881 atgaagacag gctgggtcaa gtacaaggac acttggtact acttagacgc taaagaaggc
     8941 gccatggtat caaatgcctt tatccagtca gcggacggaa caggctggta ctacctcaaa
     9001 ccagacggaa cactggcaga caagccagaa ttcacagtag agccagatgg cttgattaca
     9061 gtaaaataat aatggaatgt ctttcaaatc agaacagcgc atattattag gtcttgaaaa
     9121 agcttaatag tatgcgtttt cttgtggaga tatttccttc aattttgcta ctatattaaa
     9181 caaaaatcaa aaagcaaact agaaagttat gctcaaataa aatctaaatt tgacaatgta
     9241 aaccgagtcg gatagcttta agtactgttt tgaggttgaa gatacgattt ttgataggaa
     9301 ctcatcaatt ttagattttt aagcagcatc aataaattgc ttccttgttt tgtcataatt
     9361 tttttattta aaaaattatg acaagagtgt gctattcttt ttatgagagg tgtatgaata
     9421 tgataaatgt atgtgataaa tgtatgtgat gttggaaaaa gaataaaaga acttagaata
     9481 tcttcaaatc ttactcaaga taagattgct gagtatttgt ctttgaatca aagcatgatt
     9541 gccaaaatgg aaaaaggtga aaggaatatc acgaatggat ttaagtaata aagcttcaaa
     9601 tcttagaaaa aagttgggag ctgatggtga atcgccgata gatattttta aattggtaca
     9661 aaagatagaa aatttgacgc tggtatttta tggactcgga aagaatatta gcggagtctg
     9721 ttataaagga actcagttca gtctcattgc agtcaattca gacatgccat taggaaggta
     9781 aagattttct ttagcacatg gactgtatca tctttattat gatgaggtga agaagagttc
     9841 agtcagtctt atcttgattg gtgaaggaga tgaaactgaa agaaaagcgg atcagtttgc
     9901 ttcttatttt ttaattttcc catcttcact gtataggatg gttgaggaaa tcagagaaaa
     9961 tgccaataga actcatcttg aagtagaaga tattataaaa ttgggtcagt tttatggtat
    10021 cagtcataaa gctatgttat atagattgag aaatgatgga taccttgatg cagaagaaat
    10081 taaaaatatg gatattagtg ttatagagac agcttcaaga ttaggctatg atacaagttt
    10141 atatcgtcct ttgtcagaaa gtaaaaagga aatggtatta ggacactata ttaaatcgac
    10201 tgaacaactt ttagaaaata acagaatttc gcaagggaag tatgaggaac tgttactaga
    10261 tgctttcaga tatgatattg tatatgggct agatgaagag ggggagttgt cgtttgacta
    10321 gtcgtgtatt tattgatgca gattgtattt cagcattttt atgggttggc actgaacatc
    10381 ttttagaaaa gctctattcg ggtaaaattg ttattccaca agaggtgtat gatgaaatca
    10441 atatacctac aattccccat ttaaaatcta ggatagacca gttggtaact aagggttcag
    10501 ctgagattgt gagcatagac attggaactg aagaatacgc attatataga gatttaacaa
    10561 gaaattatga tagtaacaag attattggta agggagaagc gacttctatt ttcttagcga
    10621 aaaagcataa tgggatatta ggaagtaata acctaagaga tgttaaacca tatgtagaag
    10681 aattttcttt agaacatatg acaacaggag atatactgat tgaagcgttt aaagcgtaat
    10741 ttattactga ataagagggc aatcatatct ggaataatat gcttaaaaag agaaggaaaa
    10801 ttggtgcaaa ttcattttca gactatcttc gtggaagtat tcatcaaaat agacaaaaat
    10861 aaatttggat aaatcgaact cactattcag gaggcatatg agcaattcga aaaagaaaag
    10921 tgtcaaattg agcctatagg agtagaagtg aaatagtaag tcctgcatag tggatgagag
    10981 aaaagttctc cttgaagttt tcctgaacta tcagtcgcat gtcaaacgat atgtagggta
    11041 atgtgagagg ggatagggag tagtttttgg ttattttatc aaaaaactta tattttatta
    11101 taccgaatga taaaatataa taaaaatgat agaataagga aaaaacatga atgtcaaaaa
    11161 gataatgtca atttttcaat ccttttatgt tgatgtcagt attgaggaac tgactttgac
    11221 tttaccaatc agttttgtaa aaaggtttga gtatactcaa atgacttttc ataaggaatc
    11281 atttttattg attaaagaaa agagaagggg gagtttgagt tcatttgtta ctcaggctcg
    11341 cactatgggt gaaaaagcca atatggatgt tgttttggtg ttttcgaagt tatcagacag
    11401 tgaaaaaaag caattacttc aagctagagt tccgtttgta gactttaagg gaaacctctt
    11461 cttccctcca ttgggactag tactcaatgc gaatgatact gaagtcccta aggaattaac
    11521 acctagcgaa caattaacgt ggattgcctt tttattgaca aaaggtcaaa aagtagtaga
    11581 tgttgatttg ctttcacaag tcactggact tccaaactca acaatttata ggtgtttgag
    11641 gacttttaaa gctttatatt ggttaaacaa gcaaaataag ctttacacat atacggtgtc
    11701 aaagaaagaa ttattcttaa aatccgtgtc atgtttattt aatcccatca aaaaacggat
    11761 tttattgcca gatggcgata taaagcagat aaaatctgtt tctaaccttc tatatggtgg
    11821 tgcttatgct ttgtcgcatt caactttttt agctgaaacg gatgaaaata ttagctatgt
    11881 catatggcag agaaaattca atcagttatc cttgccactt tctcagcatg ttttaaaatg
    11941 aaagatgcta gagatatgga aatatcgtcc ttttgtatct gagttttgga atgattttaa
    12001 aaataatcat gataaacaat ttgtagatcc gatttctctt tatttgacct taaaagatga
    12061 tgatgaccca cgtatagagg aagagagtga agcactagaa aatatgatat tacagtatct
    12121 gggagaagat gatgccagct aatacgaaag ttatttttca agaaatgttt gcggattttc
    12181 agaactatta tgttctgatt gggggaactg ctacctctat cgtattggat tcgcaaggat
    12241 ttaaaagtcg cacaacaaaa gattatgata tggtcatcat tgatgaagta aaaaataagg
    12301 aattttatac taccttgaat cattttttag aattgggaga gtatcaagga agtcagaaag
    12361 atgagaaagc gcagcttttt cgatttacaa caactaatcc tgagtttcct tctatgattg
    12421 aactatttag tatcttacca gaatatccat taaagaagga cggtcgagaa attcccttac
    12481 attttgacca agatgctagt ttatcagcct tattattgga tgaagattat tataatatat
    12541 tggtgcatga aaaagaaacc attcaggggt attcggtatt gagtaattgt ggtttatact
    12601 cttcgaaaat ctcttcaaac cacgtcagct tccatctaca acctcaaaac agtgttttga
    12661 gcagcctgca gctagcttcc tagtttgc
//
LOCUS       DAVHSH010000050        12596 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000050 DAVHSH010000000
VERSION     DAVHSH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.051"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            190..999
                     /locus_tag="VVR08_001637"
     CDS             190..999
                     /locus_tag="VVR08_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6075523.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            1004..1705
                     /locus_tag="VVR08_001638"
     CDS             1004..1705
                     /locus_tag="VVR08_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6075524.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1730..2647
                     /locus_tag="VVR08_001639"
     CDS             1730..2647
                     /locus_tag="VVR08_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU6075525.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2675..4216
                     /locus_tag="VVR08_001640"
     CDS             2675..4216
                     /locus_tag="VVR08_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEU6075526.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4235..4693
                     /locus_tag="VVR08_001641"
     CDS             4235..4693
                     /locus_tag="VVR08_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6075527.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4695..6917
                     /locus_tag="VVR08_001642"
     CDS             4695..6917
                     /locus_tag="VVR08_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEU6075528.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6957..8066
                     /locus_tag="VVR08_001643"
     CDS             6957..8066
                     /locus_tag="VVR08_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6075529.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8223..9113
                     /locus_tag="VVR08_001644"
     CDS             8223..9113
                     /locus_tag="VVR08_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6075530.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            9138..9461
                     /locus_tag="VVR08_001645"
     CDS             9138..9461
                     /locus_tag="VVR08_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075531.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9451..11442
                     /locus_tag="VVR08_001646"
     CDS             9451..11442
                     /locus_tag="VVR08_001646"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEU6075532.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11458..11934
                     /locus_tag="VVR08_001647"
     CDS             11458..11934
                     /locus_tag="VVR08_001647"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEU6075533.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11968..12549
                     /locus_tag="VVR08_001648"
     CDS             11968..12549
                     /locus_tag="VVR08_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075534.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
BASE COUNT         4294 a         1796 c         2474 g         4032 t
ORIGIN      
        1 gtgataaacg ttcttacaat acatataatt acgataaaaa gaataaaaac tattatattt
       61 ttatgtttgt tgttctgtta tgaaacgaaa gaaattggaa actagtttct aatttatgaa
      121 aaatattgaa aaaaaaaaaa aagtgttaaa ataaagaatg taaacgttta cttcaactaa
      181 ggagctcata tgttactgca aaaagaacta attccaatga tagaagctaa cttaccaaat
      241 atggcatatg ctgaaaaaga cattgctaaa ttcttcttaa aacagcaacc tctgaatgat
      301 tattcatcta aagcattgtg cgaatacctt aatgtatcca aagcaacatt gactcgattt
      361 gcgaaaaaat gtggttttaa aggttttaga caattcattt tcaaatacca agagatgatt
      421 catgagaaag aaaagttggc attatataca gaggcaacag aaaaagtttt atccgactat
      481 gaggaaatgt tgagaaaaac ttacacggtt cttgatgaag ttcaacttga gcgtattgct
      541 gagatgatag aaactgctga gcgtgtatat ctctacggta aaggaagttc tgttcttgct
      601 ttacaagaaa tgaagatgag atttatgcgt ctcggagtga ttggtgaagt attatcagac
      661 gaggatatga ttttgtggag tagcttacta cttaatgaaa attgccttgt cattggagca
      721 tccatttcag gtcaaactga tattgtacta gaaggtctac aaaaagctgc agataaaggc
      781 gctaaaacag ttttaatgac tacaagaaaa tttgacgaag aagattgttt ctttgatgaa
      841 ctattgttat tagcttcgac cgatcatctc tcgtatggca atcgcatatc acctcagttt
      901 ccaatacttt taattacaga ctgcttattc tctaattatc tggaaagtcc agagagacaa
      961 tattattaca atcaaactat tatccataag gaggaataat aaaatgagcc aaatttggac
     1021 taaagaaaaa tttataagcc aagttcaagg tggagtcatt gtttcttgtc aagctttacc
     1081 tggtgaagcc ctttataatg aagaatttag cttgatgcct tttatggcta aagcagcttt
     1141 agaggcagga gcagtgggca ttcgcgcaaa ttctgtgcgt gatattaaag caattcagaa
     1201 agtagtagat ttaccaataa ttggaattat caaaagggat tatccacctc aagaaccata
     1261 tattactgct acgatgaaag aagtagatga acttgtagaa tgcggaacaa cagtcattgc
     1321 atttgatgca actttaagac caagatatga tggcttagtt gtcagtgaat ttatcaaaaa
     1381 aataaaagaa aaatatccga atcaattgct gatggcggat gtaagtaatt tagatgaagg
     1441 tctctatgca tttaaatcag gcgttgattt tgttggtaca acattatcag gttacacaag
     1501 tacaagtgta caatcagatg agcctgattt tgaactaatg aaaaaattgg ctgattttaa
     1561 tattccggta attgccgaag gaaaaattca ttatccagaa caattaaaaa aagcttatag
     1621 tttaggtgtt accagtgtag tcattggtgg agcgattaca cgtccaaaag aaattgctca
     1681 gcgatttatt aatgtcatca aataaaaaac aatataaagg agaaatctga tgaaagattt
     1741 aactaaatac aaaggcgtta tccctgcatt ttatgcttgc tatgatgaaa atggtgaaat
     1801 tagccaagat cgtgtaaaat ctctggtaca atatttcatt gacaaaggtg taaaaggtat
     1861 ctatgtaaat ggttcttcag gtgaatgtat ttaccaaagt gtagaagatc gtaaacaaat
     1921 tattgaagct gttatggaag ttgctaaagg taaattaaca gttatcaacc atattgcatg
     1981 taataacacg aaagatagta tcgaattggc aaaacattca gaaagtgttg gagtcgatgc
     2041 tattgcagct atcccaccta tttatttcaa attgccagag tattcaatcg cagcatattg
     2101 gaatgcaatg agtgaagctg cgtcaaatac agattttatt atctataata ttccacaatt
     2161 ggcaggggtt gcgttgactg gtagtttgta tgcaacaatg cgtcaaaatc ctcgtgtgat
     2221 tggagttaaa aattcttcta tgcctgtaca agatattcaa atgtttgtag ctgcaggtgg
     2281 agaagattac attgtattca atggtccaga tgaacaatat cttggtggtc gcttgatggg
     2341 agcagaagct ggtattggtg gtacttatgg cgttatgcca gatttgttct tgaaattgga
     2401 aagtttgatt caagaacgag atttagatac agctaaaaaa cttcaatatg ctatcaatga
     2461 agttatctat aagatgatat caggtaaggc aaatatgtat gctgtagcaa aagaagtttt
     2521 gcgtctaaat gaaaaacttg atttaggttc tgttcgtcaa cctttagaag cattggcaga
     2581 aggtgacttg gaagttgcaa aacaagcagc agaacttatt caacaagcac gaaaagaatt
     2641 tttataataa ataaaatcaa tatggagata tgttatgggc acaacaggat ttacaataat
     2701 tgacttaatt atcttgattg tttatttact tgcggtgttg gttgcaggta tctatttctc
     2761 taaaaaagag atgaaaggaa aagagttctt taaaggagat ggttcggttc cttggtatgt
     2821 tacttcggta tccatttttg ccacaatgct cagtccgatt tccttcttgg gactcgctgg
     2881 tagctcttat gcaggtagct ggattttatg gtttgctcaa ttagggatgg tagtagctat
     2941 tccactgaca attcgtttta tcttacctat ctttgcacgg atagacatcg atacggcata
     3001 tgattacttg gataaacgtt ttaattctaa agcacttcgt attatttcag cactcttgtt
     3061 tattatttat caattgggac gtatgtctat cattatgtac ctcccatcag ctggtttatc
     3121 agtattgaca ggaattgaca tcaatatttt gattattttg atgggtgtag ttgcaattgt
     3181 ttattcttat actggtggtc taaaatccgt attatggaca gactttattc aaggtgtgat
     3241 tctgattagt ggtgtcgttt tagctttatt tgtactgatt gctaatatta aaggtggctt
     3301 tggtgcagta gcagaaacat tagcaaacgg gaaattcctt gctgcaaatg aaaaactttt
     3361 cgatcctaac ttgctttcaa actccatctt tttaattgtg atgggttcag gctttacaat
     3421 cttgtcttcc tatgcttcat ctcaagattt ggttcaacgt tttactacaa cacaaaatat
     3481 taagaaactt aataagatgt tgttcacaaa cggtgttttg tcacttgcaa ctgcaacagt
     3541 cttttacttg attggtacag gcttgtacgt attctatcaa gtacaaaatg cagatagtgc
     3601 agctagcaat atccctcaag accaaatctt tatgtacttt attgcatacc agttaccagt
     3661 aggtatcaca ggtttgatct tggcagcgat ttatgcagca tctcaatcaa ctatttcaac
     3721 aggtttgaac tctgttgcaa cttcatggac attggatatt caagatgtca tttctaaaaa
     3781 tatgtcagac aatcgtcgta cgaaaattgc acaattcgta tctctagcag taggtttatt
     3841 ctcaattggt gtttccattg tcatggctca ctcagatatt aaatctgcat acgaatggtt
     3901 caatagtttc atgggacttg tacttggtct acttggtggt gtatttattc ttggatttgt
     3961 ttctaaaaaa gcaaataaac aaggtgctta tgcagcgctg attgtatcaa ccatcgtcat
     4021 ggtatttatt aaatacttcc ttcctccaac agctgttagc tactgggcat attcattgat
     4081 ttcaatctct gtatcagtag tttcaggtta tattgtatct gttcttactg gaaataaagt
     4141 atctgcacct aaatatacaa cgattcatga tattacagaa attaaagcgg attcaagttg
     4201 ggaagttcgt cactaataga aaagagaaaa taatatgatt atttctgaac aatctgattt
     4261 taaacgatat gcttctgtca ataaatattt ttcaaaagtc tgtgattttt tagaaaatac
     4321 aaatttgaca gatttagttg atggaaaaat tgatattgac ggggaaaatg tttttgcaaa
     4381 ttgtatgact tatctagctg atggagttcc aggagatatt tttgaaactc ataagaaata
     4441 tttagatatt catattgttg ttgaaaatac tgaaaaaatg gcagtaactt ccccagttcg
     4501 tgcccagtca cgtgtacctt ttagcgaaga gaaggatatt gctttttacg atagcaaaga
     4561 ctatcaaatt gttgaattgc ttccagggaa tatgttggtg acttttgaag aagatcttca
     4621 ccaaccaaag attcattgca atgatgaaac tgttaaaaaa cttgttatca aagttttaaa
     4681 cgaggaaaaa taaaatgaaa aaaaatatta aacaatatgt aaccttaggt actgtagtgg
     4741 tattatcagc atttgttgct aactcagttg cagctcagga gactgaaact tctgaagtat
     4801 caacaccaaa gttggtgcaa cctgttgcac caacgactcc gatttcggaa gtacaaccta
     4861 catcggataa ctcttcggaa gttactgtac aacctcgaac agttgaaact actgttaagg
     4921 atccatcttc tacagcggaa gaaactcctg tcttagaaaa aaataatgtt actttaacag
     4981 ggggcggaga aaatgttact aaagagttaa aggataaatt tactagcggt gactttactg
     5041 tagtgattaa gtacaatcag tcaagtgaga aaggcttaca agctctgttt ggaatatcta
     5101 attccaaacc cggtcaacaa aatagttatg tagatgtgtt ccttagagac aatggtgagt
     5161 tggggatgga agcgcgtgat acttcttcca ataaaaataa cctagtatcc agacctgctt
     5221 cagtttgggg taagtacaaa caagaggctg tgactaacac tgttgcagta gtagcagatt
     5281 cagtcaaaaa aacatattct ttatacgcaa atggtacaaa agtagtagaa aagaaagtgg
     5341 ataatttcct aaacatcaag gatattaaag gtattgatta ctatatgctt gggggagtga
     5401 aacgtgcagg aaaaacggcg tttggtttta acggaacact agaaaatatc aaattcttta
     5461 atagtgcatt ggatgaagaa actgttaaaa agatgacaac aaacgctgtt actggacatt
     5521 taatttatac ggctaatgat acaacaggtt ctaactattt ccgtattcca gttctgtata
     5581 cttttagcaa tggtcgggta ttttcaagca ttgacgctcg ttacggtgga actcatgatt
     5641 tcttgaataa aattaatatt gctacaagtt atagtgatga taatggtaag acatggacta
     5701 aaccaaaatt aacattggca ttcgatgatt ttgcgccagt accattagaa tggcctcgtg
     5761 aagttggtgg acgtgactta caaatcagcg gtggtgcaac ctatattgac tctgttattg
     5821 ttgaaaaaaa gaacaaacaa gtactcatgt ttgctgatgt gatgcctgct ggagtaagtt
     5881 ttagagaagc aactagaaaa gattcaggtt ataaacaaat tgatggtaat tattacctta
     5941 aattaaggaa acaaggtgat actgattaca attatactat tcgtgagaat ggtactgtat
     6001 acgacgatcg taccaacaga ccaactgaat tttcagtaga taaaaatttc ggtattaaac
     6061 aaaatggtaa ttatttgacg gtagagcaat attcggtttc atttgaaaat aataaaaaga
     6121 ctgaatatcg taatgggact aaagtccata tgaatatctt ctacaaagat gcattgttta
     6181 aagtagtgcc aacgaactat attgcatata tttctagcaa tgatcatggc gaatcttggt
     6241 ctgcaccaac tttattacct cctataatgg gacttaatcg gaatgcgcca tatttaggtc
     6301 ctggacgtgg aatcattgaa agctcaactg gacgtattct tattccgtct tacactggta
     6361 aagagtctgc gttcatttat agtgacgata atggagcatc ttggaaagtt aaagtagtgc
     6421 cacttccttc tagttggtca gcagaagcac aatttgtaga attgagtcca ggagtaattc
     6481 aagcatatat gcgtacaaat aatggtaaaa ttgcatattt aacaagtaaa gacgcaggta
     6541 ctacttggag tgcaccggaa tatttgaaat ttgtttcaaa tccaagttat ggaacacaat
     6601 tatcaatcat caattatagc caattgattg atggtaaaaa ggctgtcatt ttaagtactc
     6661 caaactccac aaatggtcgt aaacacggac aaatttggat tggtctaatt aatgatgata
     6721 atacaattga ttggcgttat catcacgacg ttgattatag taactatgga tactcatatt
     6781 caacattgac agagttacca aatcatgaaa ttggattgat gtttgaaaaa tttgattcat
     6841 ggtctcgtaa tgaacttcat atgaaaaatg ttgtaccata tataacattt aagattgaag
     6901 atctgaaaaa gaattaaagc tgaaatttga aaatatataa aaagaggata aaaattatgg
     6961 taaattacgg tattgttgga gctggatatt ttggagctga tttagctcgc tcaatgaaca
     7021 aaattgaaga tgcaaaagtg gttgcggtat ttgacccaaa tcatggagaa gaagttgctc
     7081 aagagttggg atcagatgtt tgtgcaagtt tagatgaact tgtagcacgt gaagatattg
     7141 attgtgtgat cgtagcttca cctagctacc ttcaccgtga accagttgtg aaagctgctc
     7201 aacatggcaa acacgtattt tgtgaaaagc caattgcatt gtcttatgaa gattgtaaag
     7261 ccatggttga cgcatgtaaa gaaaataatg tcatctttat ggctggtcac atcatgaact
     7321 tctttaacgg tgtacaccat gctaaagaat tgattactca aggtaaaatc ggtaaagttc
     7381 tttattgcca tgctgctcgt acaggttggg aagaacaaca accaactgta tcatggaaga
     7441 aacttcgttc tcaatctgga ggacatttgt accaccatat tcatgaatta gattgcattc
     7501 agtttatcat gggaggactt cctgaaaaag cgacaatggt aggaggcaat gtatatcata
     7561 aaggtgaaaa ctttggtgat gaagatgata tgctcattgt aaacttagaa tactctgatg
     7621 atcgttatgc tgttttggaa tatggtaatg ctttccgttg gggtgaacac tacgtcttga
     7681 ttcaaggaac tgaaggagct atcaaacttg acttgttcaa tactggcggt actcttcgtg
     7741 ttaaaggtga aggagaatca cacttcttag ttcatgaaac tcaagaggaa gatgatgatc
     7801 gtacagctat ctataccggt cgtggtatgg atggagcaat tgcgtacggt aaaccaggag
     7861 tacgttgccc attatggttg caaacatgta ttgataaaga aatggaatat ctacatgaca
     7921 tcattaaagg tggagaaatt acagaagaat ttgaaaaact tctcaatggt gtagctgctt
     7981 tagaatcaat cgctaccgct gatgcatgta ctttatcagt taaagaagat cgaaaagtaa
     8041 gtctttcaga aatcacaaat gcttaacttt tgtaaaacag aatagtaaat tcttgtcatt
     8101 atataatttc taaagttctg tgatacaact cattgaataa agaaatagag atgggactgg
     8161 gataatgccc agtcccattt tttatcaaaa agtaatgaga tcaaaaatgt gggagtgttg
     8221 aaatgaagat tataggtatc gatattggcg gaacaacaat taaggcagat ttatacgatg
     8281 agtttggaac gagtttgaat catttcaaag agatagaaac aattattgac tatgatttgg
     8341 gaacgaatca gatattaaat caggtctgtg atttaattgg tgagtatact ttaaatcatt
     8401 caattgatgg tgttgggatt tccactgctg gagttgttaa tgctaatact ggagaaatca
     8461 tctatgcagg ctatacaata ccagggtata tcggagtaaa ctttactgcc gaaatagaaa
     8521 aacgttttgg gttgtatact tttgttgaaa atgatgttaa ttgtgctgca ttaggtgaat
     8581 tgtggaaggg acaagccaaa gataagaaaa atgtagtaat ggttactatt ggaacaggta
     8641 taggaggcag tattattgtc aacggacaaa ttgttaacgg atttaactat actgctggtg
     8701 aagtaggtta tattcctgta ggtaattcgg attggcaaag taaagcctca acaaccgcat
     8761 tgattcattt atatcaaaaa aagagcttga aaactaatca aactggacgt actttcttca
     8821 ctgatttaag atctggagat aaagttgctg aagaaacttt tgaaattttt gtagaaaatc
     8881 taacaaaagg tttattaacg atttcttatc tacttaatcc agaaattctc atattaggag
     8941 gtgggattct ggatagtaag gatattttgt tacctgaaat tcaaagttct ttagctaaaa
     9001 atgcaatgga taataggttt ttacctaaaa atcttgtggc agctacatta ggaaatgaag
     9061 ctggtcgtat aggagctgta aaaaatttct tagatagaat ttctaataaa tagtatgtaa
     9121 gataaggagg tgtcacaatg actaactctg tattttcgac aatgcaagat attgagaatg
     9181 ttgcaaccga tattataaaa tcatatgata atgagattta tacttataaa gctgtttccc
     9241 aagaagaatt ggaaaaacta gaaaaaagtt atgatgaaaa aagtcacgaa gaattagttt
     9301 caatagaaag caatttagaa atgaaacaac agaaccttat tgatgaggtt aataaaacaa
     9361 tcaaggaaaa tgatgcaaat attcagtata tttcatcaag taggagagga gaatttgtag
     9421 aaaaaattat tggtagggtg gtagaaaaat atggccatta gtcagatgaa aagaatctct
     9481 ctactatttt ctaaaagtag tcttgatgat gttttaaaaa ctattcaaga actagagtca
     9541 gtgcagttcc gtgatttaaa ggttcaggat aactggtcag aagctctaga aaaagatgaa
     9601 gttgtatttc caactattca aatttttcat acttctaatt ccaatcatgg ggttattgag
     9661 ggaaatgatg ccttgactta tttgatgaat caacaacaac atttagaagc aactgtagag
     9721 aaattacaag aatacctacc gaaagaaaac acgtttaaat tattgcagca acctccgata
     9781 actacctctt atgaagaatt agagaaattt ggtaaagcta atgttgctga gggtgttctt
     9841 aaaaaagtga atcatcaaat taacagagtt catgaattag aaagacacat tcaaagtaat
     9901 aatgaggaaa tagagcgatt aataaagtgg gaaaaattag aaattgttcc tgcgaattta
     9961 gaacaatttt ctttctgtaa aggaaaagtc ggaacaattc caaggactga agataatcgc
    10021 ttatacaata gtcttttaga aaacaatatt gaagttcaag aaatattttc taatgataga
    10081 gagtacggtg ttgttgtttt ctatcagtct agttactcta tagattttga tgaatactta
    10141 tttgaaccat ttgattattc tagaaaggaa ttaccgaagc agcgagtagt agatttagat
    10201 caagaaaaca tgcagttaat aactgaaaaa gagaatatta tcgcatcgtt gcaagattca
    10261 aagaaatatt tgatagattt acaatggcaa atagactata ttttatctat ctatgctcgt
    10321 caaatctcta agaataactt tttgtgcact ccgcatctag ttgcattaga aggatggata
    10381 gaagaaactc gtattttata ttttataaaa gttatggatg agcattttgg acattctatt
    10441 tatatttatg aatcggaaac attgacggat aatcaagatg aaatacctat caaattaacg
    10501 aatcattctt taattgaacc atttgaatta ttgacagaaa tgtatgctct gcccaaatat
    10561 tatgagaaag atcctacacc tgtattagca ccattttact ttacattttt tggaatgatg
    10621 gttgctgatt taggctatgg tttactattg tttttaggaa caatgttagc attaaaaatt
    10681 tttcatctac cttcagcaac taagagattt ttaaaattct ttaatatatt aggggtagcc
    10741 gttgcaattt ggggtggaat ctatggctca ttttttggat atgagttgcc atttcatctg
    10801 atatctacaa cctctgatgt catgactata ttagtagtgt cagttgtgtt tgggtttatt
    10861 acagtatttg caggtttgtt agcttcagga ctacaaaaag taagaatgaa gaaatatgca
    10921 gaagcatata attcaggatt tgcgtggtgt gttattctgc ttggcttgtt atttattgct
    10981 gttggaatgt tgatgcctga tatgagaccg ttatttgtat tagggaaatg ggtatctatt
    11041 tttaatgctg tggggatttt gattgtttct attattcaaa ccaaaagctt gtcaggtatt
    11101 ggagcaggat tgtttaatct atataacatt tcatcttata taggtgattt agttagtttc
    11161 actcgattga tggcattagg attatctgga gcaagtatag catcagcttt caatttaatt
    11221 gttggtttgt ttccgggaat attggctaaa ctgacaattg gattagtatt attcattctt
    11281 ttacatgcga tcaatatttt tctatcgtta ctatcaggat atgttcatgg agcacgtctg
    11341 atatttgttg aattttttgg taagttttat gagggtggag gaaaaccatt tcaacctttg
    11401 aaggcttctg agaaatatat taaggttatt acaaagaatt aatggaggat atatataatg
    11461 gaacatttag caacttattt ttcaacctat ggaggagctt tcttcgctgc attgggaatt
    11521 gtattggcgg ttggattaag cggtatgggg tctgcttatg gagttggtaa ggctgggcaa
    11581 tctgccgcag ctttactgaa agaacagcct gaaaagtttg cctcagcttt gatattgcaa
    11641 ttattgcccg gaacacaagg attatatggt tttgttattg gaattttaat ttggttgcaa
    11701 ttaactccag aacttccttt agaaaaaggc gttgcttatt tctttgtagc tcttccaatt
    11761 gctattgtag gatacttttc agctaagcat caaggaaatg tagcagtagc gggaatgcaa
    11821 atcttggcta aaagaccaaa agaattcatg aagggagcaa ttttagctgc catggtagaa
    11881 acctatgcaa ttcttgcttt tgtcgtatca ttcattttga cccttcgtgt ataagaaata
    11941 aatttgcaat tcaaaggagg tgtctaaatg agcaatttag aaaacttacg agagtctgtt
    12001 attgaacaag ctcatgaaaa agggcgtatg aaattattgg attccaaaaa gaagattgat
    12061 gatgaatttg aaatgcaaaa gtcgctcatt ataaagaaaa aagaagctga acatgaacga
    12121 aagttaaaag aattgcaaca gaaatatcaa ataatttttc aacaattaaa aaataaggaa
    12181 cgccaatcaa cgttagtatc aaaacagaaa atattaaaag aactttttca atctgcttta
    12241 ctagaaatgg aatcttggag tgcagataaa gaaatggagt tcatctatcg aattctggaa
    12301 cgatattcac aacaagaggt catagtaacc tttggggaac ggactttagc taaattcaat
    12361 ttggaacaat tagagaaatt gaaattctct tttccaaatt atttatttag tgaacaacct
    12421 atctcaaatg aatcaggctt acttatttca ataggtaaaa ttgatgataa ctatttgtat
    12481 aaaacattaa ttggatcgat ttctaaggaa gaaagttcaa gtatcgcaaa tcaaattttt
    12541 atcaattaag gatgaaattg gttaatcctt cttagaaatt tggagtattc caataa
//
LOCUS       DAVHSH010000051        12414 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000051 DAVHSH010000000
VERSION     DAVHSH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.052"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..429
                     /locus_tag="VVR08_001649"
     CDS             <1..429
                     /locus_tag="VVR08_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075535.1"
                     /translation="ELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNYSHDMKLFKM
                     SCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLIAEDKAYNHALSKERSKVE
                     NIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            621..2912
                     /gene="pcrA"
                     /locus_tag="VVR08_001650"
     CDS             621..2912
                     /gene="pcrA"
                     /locus_tag="VVR08_001650"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU6075536.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQNRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2955..3635
                     /gene="radC"
                     /locus_tag="VVR08_001651"
     CDS             2955..3635
                     /gene="radC"
                     /locus_tag="VVR08_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU6075537.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3632..4321)
                     /locus_tag="VVR08_001652"
     CDS             complement(3632..4321)
                     /locus_tag="VVR08_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6075538.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4339..4980)
                     /locus_tag="VVR08_001653"
     CDS             complement(4339..4980)
                     /locus_tag="VVR08_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU6075539.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5063..5278)
                     /locus_tag="VVR08_001654"
     CDS             complement(5063..5278)
                     /locus_tag="VVR08_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6075540.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5286..5633)
                     /locus_tag="VVR08_001655"
     CDS             complement(5286..5633)
                     /locus_tag="VVR08_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU6075541.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5638..6753)
                     /locus_tag="VVR08_001656"
     CDS             complement(5638..6753)
                     /locus_tag="VVR08_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6075542.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETYGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6763..7722)
                     /locus_tag="VVR08_001657"
     CDS             complement(6763..7722)
                     /locus_tag="VVR08_001657"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6075543.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7835..8404)
                     /locus_tag="VVR08_001658"
     CDS             complement(7835..8404)
                     /locus_tag="VVR08_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU6075544.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTLDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8532..9203
                     /locus_tag="VVR08_001659"
     CDS             8532..9203
                     /locus_tag="VVR08_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU6075545.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRSITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9187..10005
                     /locus_tag="VVR08_001660"
     CDS             9187..10005
                     /locus_tag="VVR08_001660"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU6075546.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10002..10898
                     /locus_tag="VVR08_001661"
     CDS             10002..10898
                     /locus_tag="VVR08_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6075547.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSYIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10942..11916
                     /gene="pta"
                     /locus_tag="VVR08_001662"
     CDS             10942..11916
                     /gene="pta"
                     /locus_tag="VVR08_001662"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU6075548.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(12232..>12414)
                     /locus_tag="VVR08_001663"
     CDS             complement(12232..>12414)
                     /locus_tag="VVR08_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075549.1"
                     /translation="KIVNALQLPYSNAKLEATNNLIKLIKHNAFGFRNFENFKKRIFI
                     ALNIKKERTKFVLSRA"
BASE COUNT         3635 a         2364 c         2675 g         3740 t
ORIGIN      
        1 gaattagcga atcattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
       61 acaagtcaag ggagaattgt ttctttggat atcgctgtga actatagtca tgatatgaag
      121 ttgttcaaaa tgagttgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
      181 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
      241 aagccgctaa tagctgaaga taaagcttat aaccatgcgc tatccaagga gagaagcaag
      301 gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
      361 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa tcatgaacta
      421 ggattctagt tttgcaggaa gtctattgag gtattgagct agtttatgaa aaaattgggt
      481 gaaaaagtcg agtgttttag aaacccacag tgtagtattc tagtttcaat ccactatatt
      541 ttgctactcc ccgtaaagtt tctattttcc ctgatttctg atataataga aatattgact
      601 tcaagagtaa ggaagagaag atgaacgcat tattaaatgg aatgaatgac cgtcaggctg
      661 aggcggtgca aacgacagaa ggtcccttgc taatcatggc aggggctggt tctggaaaga
      721 ctcgtgtttt gacccaccgt atcgcttatt tgattgatga aaagctggtc aatccttgga
      781 atatcttggc cattaccttt accaacaagg ctgcgcgtga gatgaaagag cgtgcttata
      841 gcctcaatcc agcgactcag gactgtctga ttgcgacctt ccactccatg tgtgtgcgta
      901 ttttgcgtcg cgatgcggac catattggct acaatcgtaa ttttacaatt gtggatcctg
      961 gtgaacagcg aacgctcatg aaacgtattc tcaaacagtt gaacttggat cctaaaaaat
     1021 ggaatgaacg aactattttg gggaccattt ccaatgctaa gaatgatttg attgatgatg
     1081 ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat tgtggcccag tgttatacag
     1141 cctatcaaaa agaacttcgt cagtctgaat ccgttgactt tgatgatttg attatgctga
     1201 ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta ctaccagcaa aaattccaat
     1261 acatccacgt tgatgagtac caagatacca accacgctca gtaccaatta gtcaaactct
     1321 tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc ggaccagtct atctacggtt
     1381 ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa ggattacccc aaagccaagg
     1441 ttgttttgtt ggaggaaaat taccgctcaa ccaaaaccat tctccaagcg gccaacgagg
     1501 ttattaaaaa taataaaaat cgccgtccta aaaatctctg gactcaaaac gctgatgggg
     1561 agcaaatcgt ttactatcgt gccgatgatg agctggatga ggctgtattt gtagccagaa
     1621 ccatcgatga acttagtcgc agtcaaaact tccttcataa ggattttgca gttctctatc
     1681 ggactaatgc ccagtcccgt acaattgagg aagccctgct caagtctaac attccttata
     1741 ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat tcgcgatatt attgcttatc
     1801 tcaaccttat tgctaatttg agtgacaata ttagttttga gcgtattatc aacgagccta
     1861 aacgtggaat tggtctaggt acagttgaga aaatccgtga ttttgcaaat ttgcaaaata
     1921 tgtctatgct ggatgcttct gctaatatta tgttgtctgg tatcaagggt aaggcagccc
     1981 aatctatctg ggattttgcc aatatgatgc ttgatttgcg ggagcagcta gaccacttaa
     2041 gcattacaga gttggttgag tccgtcctag aaaaaacagg ttatgtcgat attcttaacg
     2101 cccaagcgac tctagaaagc aaggcacggg ttgaaaatat cgaagagttt ctttctgtta
     2161 cgaagaactt tgatgacacc acggatgtga cagaagagga aactggtctg gacaaactga
     2221 gtcgtttctt aaatgacttg gctttgattg ccgacacaga ttcaggtagt caggagacat
     2281 cagaagtgac cttgatgacc ctgcatgctg ccaaaggtct cgaatttcca gttgtctttt
     2341 tgattgggat ggaagaaaat gtctttccac ttagtcgtgc gactgaagat ccagatgaat
     2401 tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg tgcagagaaa attctctatc
     2461 tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa ttataaccgt ccgactcgtt
     2521 ttattaacga aatcagttca gacttgcttg agtatcaagg tctggctcgt cctgcaaata
     2581 caagctttaa ggcatcatat agcagtggta gtatttcctt tggtcaaggt atgagtttgg
     2641 ctcaggctct tcaaaaccgt aaacgcggtg ctgccccaaa atcaatccag tcaagcggtc
     2701 ttccatttgg tcaatttaca gctggcgcaa aaccagcatc tagcgaggca aattggtcca
     2761 ttggtgatat tgctctccac aagaaatggg gagagggaac cgttctggaa gtttcaggta
     2821 gcggtgctag gcaggaattg aaaatcaatt tcccagaagt aggtttgaaa aaacttttag
     2881 ccagtgtggc tccaattgag aaaaaaatct aattttccat ccttctcacg aataataaag
     2941 tgaggaggat ttttatgtac agtatttcat tccaagaaga ttcactatta ccaagagaaa
     3001 ggctggccaa ggaaggagtt gaagcgctta gtaaccaaga gttgctagct attttactca
     3061 ggacaggaac acgtcaagct agcgtttttg aaattgccca aaaagtcttg aacaatcttt
     3121 caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt gcagagtttg tctggtattg
     3181 ggcgtgttaa ggccatagaa ttacaagcta tgattgaact ggggcatcgt attcacaaac
     3241 acgagactct tgaaatggaa agtattctca gcagtcaaaa gttggccaag aagatgcagc
     3301 aggaattagg ggataaaaaa caagagcacc tggtggcact ctatctcaat actcaaaatc
     3361 aaatcatcca tcagcagacc atttttatcg gttctgtaac tcgtagtatc gctgaaccgc
     3421 gagagattct tcactatgca atcaagcata tggcgacttc tcttatcttg gtccacaatc
     3481 atccttcagg agcggtagcg cctagccaaa atgatgatca tgtcactaaa cttgttaaag
     3541 aagcctgcga actgatgggg attgttctct tggaccattt gattgtctct cattctaatt
     3601 actttagtta tcgtgaaaag acagatttaa tctaaagttc attaacgaca tagtcaaaga
     3661 gtttcttatc tttgggacga ttttcaaaaa gaagttctgg atgccattgg acaccgagaa
     3721 aggcgacatc atccgtactc atgacagcct caatgatacc atctttagga tcatgagcca
     3781 caacttttaa atttggtgct aagtccttga tgctctggtg gtggaaggag ttgatatgag
     3841 agatttctcc atagatttct tggagaacgg tatctggttc tgttaccaag cgttgagttg
     3901 tgtactcaac agaagaatcc tgccaatggt cttcgatatc ttggtacaaa gttccaccca
     3961 tggcaacgtt aaagagttgg gtaccacggc agacagagaa aatgggcttt ttctgtttaa
     4021 tagcttcctt gatgagggcc agttcgaaga tatctctttg aaggtgataa tcatcgctat
     4081 caatggtttt gggttcgcca tagaattttg gatcgacatt ttgcccacct gtcaagatga
     4141 gcttgtcaat caaactgata tagtggcagg ccatttcttg atcaccaatc ggtaggatga
     4201 tgggaatccc tccagcatct ttaacgcctt caacaaagcc ttttgctgcg tagctcatca
     4261 tgatgtcatc atctggatga gttttttcgt ttcctgtaat cccaataact ggttttttca
     4321 taaaatgatt ttcgctttct aatcctcttt tcgcatgaag tagaggaggg tttggagttc
     4381 acttgtcaaa tcgacatact gaacgaccac gtcttttggt aaatgcagat ggactggtga
     4441 aaaactgaga attcctttca caccagcatc aaccaagaga ttagcaacct cttgtgactt
     4501 gacgctggga acagttagga tagcagtctt cacatcagca tccttgattt tatccttgat
     4561 ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg gtaccgactt caggatggtc
     4621 gtctaggtca aaggccatga taatcttcat cttgttacgt tcgtggaagc ggtagtggag
     4681 aagggcatgg cccatatttc caataccaac cagcatgaca ttggtaatag agttgtcatt
     4741 gagcaaatcg gcaaaaaatg tcattagttt tttgacatca tagccaaaac cacgacgacc
     4801 aagttcacca aaataggaaa aatcacgacg tacggtcgct gaatcaatac cgatagcctc
     4861 tgcaatttgc ttagagttgg cacgttcaat cttttctgca tgaaatctct taaaaattcg
     4921 atagtagaga gagagtcttt ttgctgtagc ttttggaata gcaaactgtt tatctttcac
     4981 aaaatcacaa cctttctatt cttctatttt atagaaacat tgtgaaaaaa tcaacaaaaa
     5041 taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa atctgcatga gatagaaaac
     5101 ggtagaggtc tccgaccagc ccctgataaa cttttttgcc cctaaaagtc agagaagtca
     5161 cataaagtgt atctggtaag gttacacatc ctgacaaagt caacatgaga gcctcatgat
     5221 cctcatactt gagagtacgc tctacatgat agcagtcctt ataggtcagt tcaaacattt
     5281 tggctctatc tttccgattt tgtaaagaca ccacgttcta ccaagctatc catgaggaag
     5341 tagaattttt cctgatgaat atggtggtct tctgatttga aaatatcaac tagacgaagg
     5401 ccaaacttgt cagtgatatt gattttagcc cctgtaagtt ccttgttaat gatgattttg
     5461 agttggaagc cttcaccgct gtttggcact ttttccaaaa ggcgagtcag ttcatagtta
     5521 ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga attttttaac agaagggcta
     5581 agagtgtaat cgtaacgaca attttttaac tgaatgattt tttcaaatgc catatggcta
     5641 acctccgata atttctttta aggtttttgc gagggtttgt aggtcttcaa cggtattttg
     5701 tggcgacaaa ctgatgcgaa gggattcctt caagcgttct gaatttgcgc catacatggc
     5761 ttcaagaaca tggctggatt ggacaacgcc tgcagtacag gctgagccag tagagattga
     5821 aattccagct aaatctagcc gaaggagtaa gaggtcattt ttctgaccag gaaatccaat
     5881 attgagaaca taagggagat gatgttttcc tctattcaag taatactgaa tgccctccag
     5941 ctctgccaga aaggcagttt ctagattttg tacatgttga aaatgttctt cttgtttttc
     6001 taggtcttct tttagggctg caaccatgcc tacgatagca ggcagatttt cagttcctgc
     6061 acgttttttc tgttcctggt ctccgccatg tagataggaa tcaaagtcca tgctagatgc
     6121 gtagagaaaa ccgattccct taggaccatg gaatttgtgg gcagaagcag tgagaaaatc
     6181 aatgcccaat tcttctgaat gaattgggat tttaccaata gcctgaactg catcaacatg
     6241 ataggcagca gggtgttgct tgagtatttg gccaatttca gcgatgggca gtaggtttcc
     6301 tgtctcatta ttggcaaaca tggtagaaac caaaatcgta tcgtcacgta aagccttttg
     6361 aatttgctgg gctgtgattt cttgattttc tggctggata atggttgctt caaacccaaa
     6421 gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg tgctcgatgg cagttgtgat
     6481 gatatgtttt ccttgttctt ggtgacgaag acagtagcca atgatggtag tattattgcc
     6541 ttcagtccca ccagaagtga aaaagatatg ttgaggtttt gtccttagta actgggctag
     6601 ttcctgacgg gcttctcgca agagtttgcc agcttgacga ccatgaccat gaatactaga
     6661 aggatttccg taggtttctt gcataacctt ggtcatagct gaaatagcaa ctgctgacat
     6721 aggagtcgtt gcagcattgt ccaaataaat caaagaatca ccttatttct ttttattgta
     6781 ggcaaagagt gggctgactg gttttctttc gtgaatacgg acgatagcat caccaattaa
     6841 ctcactagca gtgatgtagc atacattttt aggagttttt tcttttgttg ctactgaatc
     6901 agtcacaaga atttctttaa tattagtatt gtcaagaagc tcagcagctc cctcgacgaa
     6961 gagaccgtgg ctagaaacag cataaatttc tgtagctcct tcacgttcaa cgattttaga
     7021 agcttcagag aaggtacgtc ctgtatttaa aatatcatca atcaagatag ctttcttacc
     7081 ttcaacatca ccaataatat aaccttcgtt acgagttgca tcgtcttgag ggtagtcgat
     7141 aatggcgata ggagcatcaa gatattcagc caggctacgc gcacgtttga cacctgaatt
     7201 tttagggcta acgacaacaa catctgaacc aagcaatcct ttatcgcagt aatgttttgc
     7261 gaatagggga acagtgaaaa gattatccac tggaatatca aagaaacctt gaacctgaac
     7321 ggcatgcaaa tcaagagtca ggatacgatc aactccagcc ttaaccagca tattggcaac
     7381 tagttttgct gtaagtggct cacgaggaca agcaatgcgg tcttgacgtg catagccaaa
     7441 atatggaagg acaacgttga tactgtgggc acttgcacgc acacaagcat cgaccatgat
     7501 taacagttcc attaggtggt tgttgacagg gaaacttgtt gattggatga tgtaaacatc
     7561 ataaccacgg acactttctt cgatatttac ttggatttct ccgtctgaaa attgacgtga
     7621 tgatagtttt ccaagtggga caccaacagc ttgggcaatt ttttgtgcaa tctcttggtt
     7681 agagttgagt gcgaaaagtt tcatgttttt tctatctgac attatagacc gtcctctgta
     7741 aactttataa atcctagtta tatttacctt acatatatga actgggattt gtgtattttt
     7801 atcttttcta ttttaccaaa aaatggagat tatttcagct atttttcata cttttgacaa
     7861 atcgaaccaa ttttgaagga gctttttggt aggaaatctg atttttctct aaaaattgtc
     7921 ggaaatcctg tttgccttgc tcatgatttt ccacttcaag ctccaattcg taatctgtca
     7981 tatcaaagta tcggctctga tccagtgcca tgagaccaat agctgttttc atttcatagc
     8041 gaagcgttgt tagacaacca agaacctgcc agttcttact ttggatacca tgtttcgcca
     8101 attcatccag tactagccct tgaggaagtt cttccttact cagatagttc tcagcatctt
     8161 ttagttgcaa tttttggttg tattccatgt ttccaacact ctgcgggact ttgagtgtca
     8221 actcagccca gtcttcaaag gttcgaatgc gcatagcgac tttcttttct cgcagttcaa
     8281 aatcaagcgt gtcgatgtag taatttgttt gaagaacagg agtgacacct gtgaactggt
     8341 cttttagacg attgtattca tcttttttca atagtgtttt caattcaatt tctaaatgtt
     8401 tcatttttct tacctttttt tatcgttgaa agcggattta tggtataata agcattgtat
     8461 ttattgtata tgaatctgga gaaaaaatca aagatatttt tgacggataa tatgagaaca
     8521 agggagaata tatgacctta gaatgggaag aatttctaga tccttacatt caagctgttg
     8581 gtgagttaaa gattaaactt cgtggtattc gtaagcaata tcgtaagcaa aataagcatt
     8641 ctccaattga gtttgtgacc ggtcgagtca agccaattga gagcatcaaa gaaaaaatgg
     8701 ctcgtcgtag cattacttat gcgaccttgg aacacgattt gcaggatatt gctggcttac
     8761 gtgtgatggt tcagtttgta gatgacgtca aggaagtagt ggatattttg cacaagcgtc
     8821 aggatatgcg aatcatacag gagcgagatt acattactca tagaaaagca tcaggctatc
     8881 gttcctatca tgtggtagta gaatatacgg ttgataccat caatggagct aagactattt
     8941 tggcagaaat tcaaattcgt actttggcca tgaatttctg ggcaacgata gaacattctc
     9001 tcaactacaa gtaccaaggg gatttcccag atgagattaa gaagcgactg gaaattacag
     9061 ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat tcgtgatgat atccaagaag
     9121 cccaggcact ttttgatcct ttgagtagaa aattaaatga cggtgtagga aacagtgacg
     9181 atacagatga agaatacagg taaacgaatt gatctgatag ccaatagaaa accgcagagt
     9241 caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa atcagtttat actcaatgat
     9301 accaatccgg atattgtcat ttccattggc ggggatggta tgctcttgtc ggcctttcat
     9361 aagtacgaaa atcagcttga caaggtccgc tttatcggtc ttcatactgg acatttgggc
     9421 ttctatacag attatcgtga ttttgagttg gacaagctag tgactaattt gcagctagat
     9481 actggggcaa gggtttctta ccctgttctg aatgtgaagg tctttcttga aaatggtgaa
     9541 gttaagattt tcagagcact caacgaagcc agcatccgca ggtctgatcg aaccatggtg
     9601 gcagatattg taataaatgg tgttcccttt gaacgttttc gtggagacgg gctaacagtt
     9661 tcgacaccga ctggtagtac tgcctataac aagtctcttg gcggtgctgt tttacaccct
     9721 accattgaag ctttgcaatt aacggaaatt gccagcctta ataatcgtgt ttatcgaaca
     9781 ctgggctctt ccattattgt gcctaagaag gataagattg aacttattcc aacaagaaac
     9841 gattatcata ctatttcggt tgacaatagc gtttattctt tccgtaatat tgagcgtatt
     9901 gagtatcaaa tcgaccatca taagattcac tttgtcgcga ctcctagcca taccagtttc
     9961 tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg aatgaggttt gaatttatcg
    10021 cagatgaaca tgtcaaggtt aagacctttt taaaaaagca cgaggtttct aagggattgc
    10081 tggctaagat taagtttcga ggtggagcga ttctggtcaa taatcaaccg caaaatgcaa
    10141 cgtatctatt ggacgttgga gactacgtta ccatttacat tcccgctgag gaaggctttg
    10201 aaaccttgga ggctattgag catccattag atattctcta tgaggatgac cactttctag
    10261 tcttgaataa accctatgga gtggcttcta ttcctagtgt caatcactct aataccattg
    10321 ccaattttat caagggttac tatgtcaagc aaaattatga aaatcagcag gttcacattg
    10381 ttaccagact agatagggac acttctggct tgatgctctt tgccaagcac ggttatgccc
    10441 atgcacgatt agacaagcag ttgcagaaga aatctatcga gaaacgctac tttgctttgg
    10501 ttaagggaga tggacatttg gagccagaag gggaaattat tgctccgatt gcgcgtgatg
    10561 aagattccat tattaccaga cgagtggcta aaggcggaaa gtatgcccat acttcataca
    10621 agattgtagc ttcttatgga aatattcact tggtctatat tcacctgcac actggtcgaa
    10681 cccatcaaat ccgagtccat ttttcttata tcggttttcc tttgctggga gatgatttgt
    10741 atggtggtag tctggaagat ggtattcaac gtcaggctct gcattgccat tacctatcct
    10801 tttatcatcc atttttagag caagacttgc agttagaaag tcccttgccg gatgatttca
    10861 gtaaccttat tacccagtta tcaactaata ctctataaaa actgtctcag agtataatta
    10921 ttatcttaaa ggagaaaact catggaagtt tttgaaagtc tcaaagccaa ccttgttggt
    10981 aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc gtattcttca agcaacaaaa
    11041 cgcttagtaa aagaaacaga agtgattcct gttttgcttg gaaatcctga aaaaattaaa
    11101 atttatcttg aaattgaagg aatcatggat ggttatgagg tcatcgaccc tcaacattat
    11161 cctcaatttg aagaaatggt ttctgccttg gtggagcgtc gcaagggcaa aatgactgaa
    11221 gaagatgtac gcaaggtttt ggttgaagat gtcaactact ttggtgtgat gttggtttac
    11281 ttgggcttgg ttgatggaat ggtgtcagga gcgattcact caacagcttc aacagttcgt
    11341 ccagctctac aaatcatcaa aactcgtcca aatgtaactc gtacttcagg agccttcctc
    11401 atggttcgtg gtacggaacg ttacctattt ggagactgtg ccattaacat caatccagat
    11461 gcagaagcct tggctgaaat tgccatcaac tcagcaatca cagctaagat gtttggcatc
    11521 gaacctaaaa ttgccatgtt gagctattct actaaaggtt cagggtttgg tgaaagcgtt
    11581 gataaggtcg ttgaagcaac taaaattgct cacgacttgc gtcctgacct tgaaatcgat
    11641 ggtgagttgc aatttgatgc agcctttgtt cctgaaactg cagctctgaa agctcctgga
    11701 agtacggtag ctggtcaagc aaatgtcttc atcttcccag gtatcgaggc aggaaatatc
    11761 ggttacaaga tggctgaacg cctgggtggc tttgcggctg taggacctgt tttgcaaggt
    11821 ttaaacaagc cagttaatga tctttctcgt ggatgtaatg cagatgatgt ttacaagttg
    11881 accctcatca cagcagctca agcagttcat caatagtgaa aactataaag cgatatacta
    11941 tgctatactg tagttatgaa actatgtacg aaaagcactg ccattaattc ctgagaacta
    12001 aattactgat tggtgtcaaa aaggaaaact tccaagcgat gatatcctgt ctatacacga
    12061 cctatagaaa tctgtaatat acatgtccgt aaaacgataa attccctttt tgattttaaa
    12121 tgagtatgaa aagagaattt tttcatgaga aaacgcataa tattaagtgt cttgacacct
    12181 gctattatgc gttttctggc tctttgtcaa ctgtagtggg ttgaagaaaa gctaagctcg
    12241 agaaaggaca aattttgtcc tttctttttt gatgttcaga gcgataaaaa tccgtttttt
    12301 gaagttttca aagtttcgaa aaccaaaggc attgtgcttg ataagtttga tgagattatt
    12361 ggtggcttcc agtttggcgt tggaataagg taattgaagg gcgttgacga tttt
//
LOCUS       DAVHSH010000052        12320 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000052 DAVHSH010000000
VERSION     DAVHSH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.053"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            115..675
                     /locus_tag="VVR08_001664"
     CDS             115..675
                     /locus_tag="VVR08_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6075550.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            676..2061
                     /locus_tag="VVR08_001665"
     CDS             676..2061
                     /locus_tag="VVR08_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075551.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNLNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2063..2713
                     /locus_tag="VVR08_001666"
     CDS             2063..2713
                     /locus_tag="VVR08_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU6075552.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2724..3416
                     /gene="tenA"
                     /locus_tag="VVR08_001667"
     CDS             2724..3416
                     /gene="tenA"
                     /locus_tag="VVR08_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU6075553.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            3421..3945
                     /gene="thiW"
                     /locus_tag="VVR08_001668"
     CDS             3421..3945
                     /gene="thiW"
                     /locus_tag="VVR08_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU6075554.1"
                     /translation="MRKHQLQVHKLTILSMMTALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            3945..4748
                     /locus_tag="VVR08_001669"
     CDS             3945..4748
                     /locus_tag="VVR08_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6075555.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            4741..5373
                     /locus_tag="VVR08_001670"
     CDS             4741..5373
                     /locus_tag="VVR08_001670"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6075556.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5582..6373)
                     /gene="thiD"
                     /locus_tag="VVR08_001671"
     CDS             complement(5582..6373)
                     /gene="thiD"
                     /locus_tag="VVR08_001671"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6075557.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIGSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6457..6555)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6739..7134
                     /locus_tag="VVR08_001672"
     CDS             6739..7134
                     /locus_tag="VVR08_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU6075558.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            7145..7516
                     /locus_tag="VVR08_001673"
     CDS             7145..7516
                     /locus_tag="VVR08_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU6075559.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            7526..9769
                     /locus_tag="VVR08_001674"
     CDS             7526..9769
                     /locus_tag="VVR08_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6075560.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFRLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            9976..11751
                     /gene="spxB"
                     /locus_tag="VVR08_001675"
     CDS             9976..11751
                     /gene="spxB"
                     /locus_tag="VVR08_001675"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU6075561.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            11862..12209
                     /locus_tag="VVR08_001676"
     CDS             11862..12209
                     /locus_tag="VVR08_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6075562.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT         3504 a         2369 c         2759 g         3688 t
ORIGIN      
        1 tttctagaaa tattttagtg ttcttgtgta ctgttctaaa ttcagtctgc tatacaaagt
       61 atttaggtcg gtcttcttga gtgccccact tttctttaaa aaaaggagtt ttttatgttg
      121 aaaaaatggc agttaaaaga tgttatcttg cttgctttct tgtctatctt ttttggtggg
      181 gttttcgttg gttcaggata tgtgtataat attctcagtc tactcttaac acctcttggt
      241 ttgcaggcct ttgccaatga aatcctcttc ggtctctggt gtatggctgc gcccattgct
      301 gccatctttg ttccgagagt cggaagtgca acgattggag aagtgctagc tgcgcttgct
      361 gaagtccttt atggtagcca atttggtcta ggagctcttt tgtctggctt ggttcaaggt
      421 ttgggaagtg aatttggttt tatcgtaact aagaatcgct atgaaagttg gctctctcta
      481 actgctaata gtattgggat tacgcttgtt agctttgtct atgaatacat taagttaggt
      541 tactacgcct tttcccttcc gtttgtcctt tccttgcttg tggtacgttt tatttctgtt
      601 tatttcttct gtaccatctt ggttcgtgcc attgtcaaac tctatcatca gtttgcaact
      661 ggaggaaaag catagatggg tctggaacta cgagcgattc agtccccaat tttctctgag
      721 ccgtttgatt ttacttttca tgcgcaagcc tttaccttgt tagttgggag cagtggttca
      781 ggaaaatcca gcctctttca aatgattgcc caagtcagtt ctcttcccta tagtggtcaa
      841 gtcctgatag atgggagcga ggtcagtcag ctttctatca tcgcacgtgt ccagaaggtt
      901 ggcattctct tgcaaaatct caatcatcaa tttaccatgg agaacttgtt tgaggagttg
      961 attttcacct tggagaatat cggctatcac cttcaggaaa ttgattctaa aatagcagag
     1021 gttgtccagc aatgtcgttg cgaggcaatc ttacaccgtc ccattcatca cctatcaggt
     1081 ggggaaaagc aaaaagcagc gctggctgtc ctctttgcca tgaatcctag ggtctatctc
     1141 ttggatgagc ccttcgcttc cattgaccgc aagagtagaa tcgagatatt ggagattcta
     1201 aaagagttgg ctcttgatgg gaagacagtc attttgtgcg accatgattt atctgactat
     1261 aaagcctata tcgactatat ggttgagcta agagacggaa aactaaggga agtgtttcaa
     1321 atcccttcct atgagatgac acaggttgct tcaaaggaag ttgcttctag cccggaacta
     1381 ttccatatgg atagaacgac ttgtgagttt ggaaatcgct ccctcttttc aattgctgat
     1441 ttcacattct atcaagggat ttcctgtatc ctgggtgaca atggtgtcgg gaaatcaacc
     1501 ctctttcgct ctattcttca atttcaaaag tataaggggc gcattgcatg gaaggggaca
     1561 gtcctgaaaa agaaaaagag tttgtaccgt gatctgacgg gtgttgttca ggaagctgag
     1621 aagcagttta tccgagtcag tctgcgagag gagcttcaat tagatggacc tgattctgaa
     1681 agaaatcagc ggatttttca agctttacga tattttgatt tggagcaggc agtcgataag
     1741 agtccctatc aattaagtgg tggtcagcaa aaaattcttc agctcttgac catcttgacc
     1801 agtaaggctt ccgtgatctt gctagatgaa ccttttgcag gtttggatga tagagcctgc
     1861 cattattttt gcaagtggat tgtggaggag aggaatcaag gaagaagttt tctgctcatt
     1921 agtcatcgtt tagacccttt gatttctgtg gttgattatt ggattgagat gactagtcag
     1981 ggtcttcggc atgtgaaaga agtgaccatt accaaaccac ttacatctca gagtagcaat
     2041 acccaagggg aggtgagata gtatggtcaa agtagcaacc cagacaccga ttatcagtct
     2101 cttcttgctg attttatcct tggaaacatc tttcattcct tcgattgctc tgaatctttc
     2161 ggtagtcgca ttttgtattc tctttatgct ctattaccgt cgatttaaaa tgttagcttg
     2221 gatgatcata cttgccattt taccatcttt tgccaactac tgggcagttc agttacacgg
     2281 agatgcttca caggcagtca tgcttggaac gagggccttt gtgacagttt gtatcggcct
     2341 tgtctttgtt tcctctattt cactaaaaga gcttctcttg tacttggctc aaaaggggct
     2401 atcacgctct tggtcctatg ccttgattgt ggtattcaat tcttttcctc tcattcagca
     2461 agaaatcaag tccctcaaag aagcttgcct attacgtggt caagaactac atttttggtc
     2521 gcccttgatt tacagtaagg ttctgatgac agtctttagg tggcgccatc tttacctgag
     2581 agctctatct gctcacggat atgacgaaca tgcacagttg aagaatagct atcggacttt
     2641 ttatattcct aaaaaaacaa aattaatcta cctgcttttc tttttattgc ttcaaaccag
     2701 tctattttta taaaggagtt attatggaat ttacagatat tgcgatggaa ttatccaaga
     2761 aagcttggca ggcttccttt catcatccct ttattttaca attacaagag gggaatttag
     2821 aacctgccat tttccgctat tacctgattc aggatgccta ctatctgaag gccttctcag
     2881 aaatctatca tcttttggct gataagactt caaaccaaga gatgaaaaga ctcttgaaac
     2941 aaaatgctca gggtttagtg gagggtgagt tatttattcg ccaacaattt ttcaaggaat
     3001 tggaaatcag cgaccaggaa atggagcaac atccaatcgc tccaacctgt tatcattaca
     3061 tttctcatat ttataggcaa tttgcagagc cgaacttagc catcgctttt gcaagcttgc
     3121 ttccttgtcc ttggttatac catgatatag gcaaatcact taatcttaaa ccatcaccaa
     3181 atcctctcta tcaacaatgg attgaaactt atattacgga tgagttagag caacagatca
     3241 gagaggaggg agcactggtc aatcagctct atcgagaaag tgatgagaca gataagcaaa
     3301 aaatgctaga tgccttccac atcagtgttc atatggaagc caagttttgg gagatggctt
     3361 accaacacca gacatggaag agcgatttac agtctttaga aaaaggagaa gaatagaaac
     3421 atgagaaagc accaactaca agttcacaaa ttgaccattt tatctatgat gactgccctt
     3481 gatgtagtcc ttacacctat ctttcggatt gagggaatgg caccgatgtc cagtgtagtc
     3541 aatattctag cgggaatcat gatgggacct gtttatgcct tggccatggc tacagtgaca
     3601 gcctttatcc gtatgacgac tcaagggatt ccgcctttag ctctcacagg agcgactttt
     3661 ggagcccttc tagcaggtct cttttataag tacggtcgaa aattttactt ttctgccttg
     3721 ggagaaattg tgggaacagg tattattggt tctattgttt cctatcctgt tatggtactc
     3781 tttacaggat cagctgctaa gcttagctgg tttatctaca cgcctcgatt tttcggagca
     3841 accttgattg gtacagcgat ttcctttatt gcctttcgat ttttaatcaa gcaggaattc
     3901 tttaaaaaag tgcagggata tttctttagt gaaaggatag actgatgcag gaatttacaa
     3961 atccctttcc tataggctct agttccctca ttcactgtat gaccaatgag atttcttgtg
     4021 agatgctggc aaatgggatt ttggctctgg gatgcaaacc tgtcatggca gatgatcccc
     4081 gtgaggttct tgattttact aagcaaagtc aggctctctt catcaatttg gggcatttgt
     4141 cagctgagaa ggagaaagca atccgtatag cagcttctta tgcagctcaa gtttgtctcc
     4201 caatggtagt agatgcggtt ggcgtaacag cttcatccat tcgtaagagc ttagtcagag
     4261 accttttaga ctatagacct acggtcctta aaggaaacat gtcagaaatt cgaagtcttg
     4321 ttggattaaa gcaccacggc gttggggtcg atgcgagtgc taaagatcaa gaaacggagg
     4381 atttgcttca agtcttgaaa gactggtgtc agacctatca tggtatgtct ttcttagtca
     4441 caggtcccaa ggacctcgtc gtttcgaaaa atcaggtcgc tgtactggga aatggctgtg
     4501 cagaattaga ctggataaca gggacaggag atttggttgg agccttaaca gccgtttttc
     4561 tcagccaagg aaagactggt tttgaagctt cttgcttagc agtctcttat ctcaatatcg
     4621 ctgctgagaa aatagttgtt caaggaatgg gattggaaga atttcgttac caagtactca
     4681 atcagctttc gctcctaaga agagatgaaa attggctaga taccatcaaa ggagaggttt
     4741 atgaatagag aagcacttag actatatctg gtaaccaatc gctatcaaga ttccgtggaa
     4801 agctttcttg caaaagttga gacggcctgc cgttcagggg ttaccatagt ccaattgcga
     4861 gaaaaaaatc tcacaaccaa tcaatattat caactggcaa aacaagtcaa ggaaataaca
     4921 gatgcttatc aggtaccctt gataatcgat gatcggttgg atgtttgtct tgcggttgat
     4981 gcagcaggtc tgcatatcgg agatgatgaa ttaccagttt cggtagctcg caaagtcttg
     5041 ggtcctgaaa aaatcctcgg tgtcaccgct aaaacggtta aaagagctct ggaagcggag
     5101 aaatcaggtg cagattactt gggtacagga gccattttcc caaccaccac caaggaaaat
     5161 gcgcccatta ctctgatatc gaccttgaaa acaatttgcc aaacggttgc cattccagta
     5221 gttgctattg gaggcttgac ttcggagaat attgatcagc ttatgggcac tggcatagct
     5281 ggtgtagctg ttgtacgtga tttgatgcaa gcagaagata ttgaggcaaa aacgcaagcc
     5341 tttttaacaa agttgcatga cattctttcc taattaatac tcaatgaaaa tcaaagagta
     5401 aactagaaag ctagtcgcag gttgctcaaa gtactgcctt gaggttttag ataagactga
     5461 cgaagtcagc tcaaaacagt gttttgaggt tgcagatgga agctgacgta gtttgaagag
     5521 attttcgaag agtataaaaa ctctctaatt cccttaaagt gggaactaga gagttttttt
     5581 cttaatcttt aaaagttgta tggttgactg gaccagaacc atgaccgagt tgaggggcat
     5641 cttgaatagc ttttgtgata aaggccttgg ccttatcaac tgcctggtaa agactcttgc
     5701 ccttggctag ttcagcagta atcactgcag caaaggtaca tccagtacca tgggtgtgac
     5761 aggtttgaat tcgtgggctt tcccagacaa attgttcatt cttggtaaag aggaaatctt
     5821 tagcaccgcc tttgagatgt ccgcctttga taaccacaga ctgaggacca aattctttta
     5881 aaatcaggcg accagcacgc tgcatgtctt cggggtcatg gattgaaaaa ccaacaatct
     5941 cttctgcttc aggaagattt ggcgtaataa tagttgctag aggtagtaag tttgttttga
     6001 gatagtctct agcatttgag ccaatcaagg catctccact tgtagcaacc ataacaggat
     6061 caaggacata gggacaatcc agttttttaa gatagggttg gatgatttcc atgatttcag
     6121 tagtagccaa cattccagtt tttacagcct gaggtggaat atcagaaaag acactctcca
     6181 attgggcttt caacatttga ggagaaacgt gctcgattag ctgaacacct ctggtatttt
     6241 gagcgacaag actggttaca acagccattc catagacatc tctcgcttgg aatgacttta
     6301 aatctgccat aatgccagca ccaccactag ggtcagtccc tgcaatggtc aaagcaacgg
     6361 gtaaataagt catctaaaac ctcccaacca actgaagttt gtattcttaa gaacaagcta
     6421 gtctgtttta gaaaggcaat agaagactgc tagtccccat tatcatttcc acttccatca
     6481 gctagcatta cctagattga gtcagaggga tctaacagtc gttaatctca gctttacgca
     6541 cccctagtgg ttgttttctt ttttctttag tatagcatat ttttattgtt tatatagtaa
     6601 tatttgactg caaatcgttt ttcaaatgat taaaattcta tttttcgaag aaaatattat
     6661 ttctataatt gacaaatgta gattttaaga gtatactgat gagtgtaatt gacaaatgta
     6721 gattttggag gtatggtaat gcagatttca gatgcagaat ggcaggtcat gaagattatt
     6781 tggatgcagg gggagcagac cagtacagat ttgattaggg ttttggcaga gcggtttgac
     6841 tggtccaagt ccacggttca gacacttttg gctcgtctgg ttgagaaaga gtgtttgact
     6901 cggaaaaaag aaggcaagtc ctttgtttat tcagcccttt taactctaga ccaaagtcgg
     6961 gatttacttg tccaagatat caaagacaag gtttgttccc gtaggattag gaatttgttg
     7021 gctgacttga ttgtagaatg tgaatttact cagactgact tggaagactt ggaagctgtg
     7081 atttcagaga agaaatcaag tgctgtaaca gaagtaagat gtaattgtat gtaaaggaga
     7141 cgtcatgtta aatagtattg taaccattat ttgtattgcc cttatcgcgt ttatcttgtt
     7201 ttggtttttc aaaaagcctg aaaaatctgg acaaaaagcc cagcaaaaaa acggatacca
     7261 agagattcga gtggaagtca tgggaggcta tactcctgag ttgattgtcc tcaagaaatc
     7321 agtgccagca cgcattgtct ttgaccgcaa ggatccttca ccatgtctgg atcaaattgt
     7381 ttttccagat tttggtgtac atgcgaacct gccaatgggg gaagagtatg tagtggaaat
     7441 cacgcctgaa caggctggag agtttggctt tgcttgtggt atgaacatga tgcacggcaa
     7501 gatgattgta gagtaggtgg agactatgac agaaattgtg aaagcaagct tagaaaatgg
     7561 cattcaaaaa atccgtatcc gagctgaaaa aggctatcat ccagcccata tccagcttca
     7621 aaagggaatt ccagctgaga ttacctttca tcgtgctact ccttcaaact gttataagga
     7681 aattctgttt gaagaagaag gtatcttgga accaatcggc gtagatgagg agaaagtcat
     7741 tcgttttacg cctcaagaat tagggcgaca tgaattttct tgtggcatga agatgcaaaa
     7801 gggaagctat acagtcgttg agaagactcg aaaatctcta tctctcctgc aacgtttttg
     7861 gattactagt atctttactg tgcctcttgt gattctcatg attgggatgt tgacaggtag
     7921 cattagtcat caagtcatgc attggggaac ctttctagca acaacgccta ttatgttagt
     7981 tgcaggtaag ccatatatcc agagtgcttg ggccagtttt aaaaagcaca atgccaacat
     8041 ggataccttg gttgcgctgg gaactctagt ggcttatttc tatagcctag ttgctctctt
     8101 tgctggtctc cctgtttact tcgaaagtgc tggatttatc ctctttttcg ttcttttggg
     8161 agcagttttt gaggaaaaaa tgagaaaaaa tacgtcccaa gctgtggaga aattactgga
     8221 cttgcaagct aaaaccgcag aagtcttgag tgatgatagt tatgtccaag ttcctttgga
     8281 acaagtcaag gtaggcgacc tgattcgagt gcgtcccggt gaaaagattg ctgttgatgg
     8341 tgtcgtagta gaaggtgtct ctagtattga cgaatccatg gtgacaggtg agagtctgcc
     8401 tgtggacaag acagttggag atactgtcat tggctcaacc atcaatcata gtggaacgct
     8461 tgtctttaga gcagaaaaag ttggctcaga gactgttttg gctcagattg tggattttgt
     8521 gaagaaagct cagacaagtc gtgcgccgat tcaagacttg acggataaga tttcagggat
     8581 ttttgtccca gtagttgtca ttttaggaat catgaccttt tgggtttggt tcgtcttgct
     8641 cagggatagt gtggttgtgc ttggagctag ctttgtgtcc tctcttctct acggagtggc
     8701 ggttttgatt atcgcctgtc cttgtgcctt gggacttgca acaccgacag cccttatggt
     8761 ggggacagga cgtagtgcca agatgggggt tctcctcaaa aatggaactg tcttacagga
     8821 aatccagaaa gttcaaaccc ttgtctttga taagaccggg actttgacgg aagggaaacc
     8881 tgtggtaaca gatgtcatcg gcgacgaagt agaagtgttt aggttggcag cctccttgga
     8941 agatgcttct caacacccac tggctgaggc tatcgttaag cgagcgagtg aagctggact
     9001 tgagtttcaa actgttgaaa attttcagac cttgcacggg aaaggtgttt cagggcgaat
     9061 caatggaaaa caagttttac ttggaaatgc taaaatgctg gatggtatgg atatttctaa
     9121 tacttatcaa gataaactag aagaactaga aaaagaagct aagacagttg tgttcttagc
     9181 tgttgacaat gaaatcaaag gcttgcttgc tttgcaagat attcctaagg aaaatgctaa
     9241 gctagccatc agtcagctaa aaaaacgtgg tctccgaaca gtcatgctga caggagacaa
     9301 tgctggtgtg gcgcgtgcta ttgcagatca aatcggaatt gaagaggtca ttgcaggcgt
     9361 cttgccagaa gaaaaagccc atgaaatcca taaactgcaa cagtcaggga aagtagcctt
     9421 tgttggggac ggtatcaatg acgctcctgc ccttagtgta gcagatgtgg ggattgctat
     9481 gggagctgga acagatatcg ccatcgagtc agcagatttg gtgttgacaa ccaataatct
     9541 tttaggagtg gttcgtgcct ttgatatgag taagaaaacc tttcatcgaa ttctactcaa
     9601 tcttttctgg gcttttatct acaatgttgt cggaattccg attgcagcag gagtcttttc
     9661 aggtgttgga ctggctctca acccagaatt ggcaggtcta gccatggcct ttagttctgt
     9721 atctgttctg accagttccc ttctgttaaa ttttagtaaa atagactaaa agtaatgact
     9781 agatttcttt gttataaaac agaaatgaca gaactttcaa aactgtatta gaatagagaa
     9841 tagagagttt tgagcagatt tttagaaaag tcagcataaa tatgatacag tggaatagta
     9901 aaaatttgga gaacgtttcc aattctatgt aatcgtattc tccaaatcta aaaaaattga
     9961 aggagagtta tcattatgac tcaagggaaa attactgcat ctgcagcaat gcttaacgta
    10021 ttgaaaacat ggggcgtaga tacaatctac ggtatcccat caggaacact cagctcattg
    10081 atggacgctt tggctgaaga caaagatatc cgcttcttac aagttcgcca cgaagagaca
    10141 ggtgctcttg cagcggttat gcaagctaaa ttcggcggct caatcggggt tgcagttggt
    10201 tcaggtggtc caggtgcgac tcacttgatt aacggtgttt acgatgcagc tatggataac
    10261 actccattcc tagcgatcct tggatcacgt ccagttaacg aattgaacat ggatgctttc
    10321 caagagctta accaaaaccc aatgtacaac ggtatcgctg tttacaacaa acgtgtagct
    10381 tacgctgagc aattgccaaa agtaattgac gaagcctgcc gtgctgcaat ttctaaaaaa
    10441 ggtccagctg ttgttgaaat tccagtaaac ttcggtttcc aagaaatcga cgaaaactca
    10501 tactacggtt caggttcata cgaacgctca ttcatcgctc ctgctttgaa cgaagttgaa
    10561 atcgacaaag ctgttgaaat cttgaacaat gctgaacgcc cagttatcta tgctggattt
    10621 ggtggtgtta aagctggtga agtgattact gaattgtcac gtaaaatcaa agcaccaatc
    10681 atcacaactg gtaaaaactt tgaagctttc gaatggaact atgaaggttt gacaggttct
    10741 gcttaccgtg ttggttggaa accagccaac gaagtggtct ttgaagcaga cacagttctt
    10801 ttccttggtt caaacttccc atttgctgaa gtttacgaag cattcaagaa cactgaaaaa
    10861 ttcatccaag tcgatatcga cccttacaaa cttggtaaac gtcatgccct tgacgcttca
    10921 atccttggtg atgctggtca agcagctaaa gctatccttg acaaagtaaa cccagttgaa
    10981 tcaactccat ggtggcgtgc aaacgttaag aacaaccaaa actggcgtga ttacatgaac
    11041 aaactcgaag gtaaaactga gggtgaattg caattgtatc aagtttacaa tgcaatcaac
    11101 aaacatgctg atcaagacgc tatctactca atcgacgtag gtaacactac tcaaacatct
    11161 actcgtcacc ttcacatgac acctaagaac atgtggcgta catctccact ctttgcgaca
    11221 atgggtattg cccttcctgg tggtatcgct gctaagaaag acaatccaga tcgccaagta
    11281 tggaacatca tgggtgatgg agcattcaac atgtgctacc cagacgttat cacaaacgtt
    11341 caatacgacc ttccagttat caaccttgtc ttctcaaatg ctgagtacgg cttcatcaag
    11401 aacaaatacg aagatacaaa caaacacttg tttggtgtag acttcacaaa cgctgactac
    11461 gctaaaattg cggaagctca aggagctgtt ggattcacag ttgaccgtat cgaagacatc
    11521 gatgcagttg ttgcagaagc tgttaaattg aacaaagaag gtaaaactgt tgtcatcgat
    11581 gctcgcatca ctcaacaccg tccacttcca gtagaagtac ttgaattgga tccaaaactt
    11641 cactcagaag aagctatcaa agccttcaag gaaaaatacg aagcagaaga actcgtacca
    11701 ttccgtctct tcttggaaga agaaggattg caatcacgcg caattaaata attcctctcg
    11761 ccgaaaatca aatatgaaac ttgtagactt tattctttga ttttcataga gcagaacttt
    11821 aaaagatcgg agcaatccgg tctttttatg gaggagagta aatgaattta aatcaattag
    11881 atattatcgt ttcaaatgtt ccccaagtct gtgctgactt ggagcatatt ttggataaaa
    11941 aggcagatta tgctgatgat ggttttgctc agtttacgat tggtagtcac tgccttatgt
    12001 tgtcacaaaa tcatttggtt cctttggaaa actttcagtc aggaatcatt attcatatcg
    12061 aggttgagga tgtagaccag aactacaaac ggttgaacga gcttggtata aaggttttac
    12121 acggaccaac tgtaaccgat tggggaacag agtccttatt agttcaagga cctgctggtc
    12181 tagtgcttga tttttatcgt atgaaatagg tcgcgtagtc atttgacgtt aaccttagct
    12241 atttttaaaa tagaaattga gaatatgaac tattgaaaga tcggagcaat ccggtctttt
    12301 tatataaaga aattgcatat
//
LOCUS       DAVHSH010000053        12216 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000053 DAVHSH010000000
VERSION     DAVHSH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12216
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.054"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            100..372
                     /gene="rpsP"
                     /locus_tag="VVR08_001677"
     CDS             100..372
                     /gene="rpsP"
                     /locus_tag="VVR08_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU6075563.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLTWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            392..631
                     /locus_tag="VVR08_001678"
     CDS             392..631
                     /locus_tag="VVR08_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU6075564.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            861..1104
                     /locus_tag="VVR08_001679"
                     /pseudo
     CDS             861..1104
                     /locus_tag="VVR08_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            1208..1996
                     /locus_tag="VVR08_001680"
     CDS             1208..1996
                     /locus_tag="VVR08_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6075565.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIYDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPIFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            2027..2545
                     /gene="rimM"
                     /locus_tag="VVR08_001681"
     CDS             2027..2545
                     /gene="rimM"
                     /locus_tag="VVR08_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU6075566.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            2535..3254
                     /gene="trmD"
                     /locus_tag="VVR08_001682"
     CDS             2535..3254
                     /gene="trmD"
                     /locus_tag="VVR08_001682"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU6075567.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            3266..3604
                     /locus_tag="VVR08_001683"
     CDS             3266..3604
                     /locus_tag="VVR08_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075568.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(3634..3954)
                     /locus_tag="VVR08_001684"
     CDS             complement(3634..3954)
                     /locus_tag="VVR08_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075569.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            4052..4267
                     /locus_tag="VVR08_001685"
     CDS             4052..4267
                     /locus_tag="VVR08_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU6075570.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(4336..4416)
                     /locus_tag="VVR08_001686"
                     /pseudo
     CDS             complement(4336..4416)
                     /locus_tag="VVR08_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4472..5008)
                     /locus_tag="VVR08_001687"
     CDS             complement(4472..5008)
                     /locus_tag="VVR08_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU6075571.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQTYFTN"
     gene            complement(5204..6550)
                     /gene="gor"
                     /locus_tag="VVR08_001688"
     CDS             complement(5204..6550)
                     /gene="gor"
                     /locus_tag="VVR08_001688"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU6075572.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            6836..8035
                     /locus_tag="VVR08_001689"
     CDS             6836..8035
                     /locus_tag="VVR08_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU6075573.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVANEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            8019..8720
                     /locus_tag="VVR08_001690"
     CDS             8019..8720
                     /locus_tag="VVR08_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075574.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            8722..9981
                     /locus_tag="VVR08_001691"
     CDS             8722..9981
                     /locus_tag="VVR08_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075575.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            10105..12102
                     /gene="metG"
                     /locus_tag="VVR08_001692"
     CDS             10105..12102
                     /gene="metG"
                     /locus_tag="VVR08_001692"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU6075576.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFCLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMVLSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT         3817 a         2220 c         2671 g         3508 t
ORIGIN      
        1 ttttcttgac acctgccaga aatctgctat aatagaacat gtgctaaata gctcagctat
       61 ttcaccgaaa taaaaaatta aagaaatgag actttaaaaa tggcagttaa aatccgtttg
      121 actcgtatgg gttctaagaa aaaacctttc taccgtatca acgtagcaga ttcacgttca
      181 ccacgtgacg gacgtttcat cgaaacagtt ggaacttaca acccacttgt tgctgaaaac
      241 caagtaactt tgaaagaaga ccgcgttctt acatggttgg ctaatggagc tcaaccttca
      301 gacacagtac gtaacatcct ttcaaaagaa ggcgtattga aaaaattcca cgattctaaa
      361 ttttcaaaat aagtttaaag taggttgaca gatggatacg attgaaaatc tcattattgc
      421 gattgtgaaa cccttaattt cacaaccaga tgccttaact atcaagattg aggatacacc
      481 agaatttttg gaatatcatt tgaatcttga tcaaagcgat gtgggtcgtg taatcggtcg
      541 taagggtcgc actatttctg cgataagaac gattgtctac tctgtcccaa ctgaatacaa
      601 aaaagtaaga atcgttattg acgaaaaata agaagggcgg gacggatgtc tcgctttttt
      661 gtgtggaata gaagatatag taaaatgaaa taataacagg acaaatcgat caggacagtc
      721 aaatcgattt ctaacaatgt tttagaagta aaggtgtact attctagttt caatatacta
      781 taaaagattg aacgtttagg caattccaag actacttact cgaacattaa cagcagtctc
      841 ggactgatga aggtctcttt atgaagttag tggaggaagt cggagaagta gccgaggttt
      901 tgaataggcg ctctggtcga aaagaaggga taggattcga acgaggaact tgccagagaa
      961 ctggctgata tcattctcta caccgtcgct attgctgcta tcaagcatat tgacctaact
     1021 agaaccatct ttgagaaaga caaaaccgca gccgttaatt accaacataa acatgatttg
     1081 gaaggattct tgaagggaaa gtagagatgt tgtccccttc ctccaacttg agaaaatcct
     1141 tggaacgtga taaaataaag gataaggatt tttaataatt cattatatag aatcagtgga
     1201 tttctttatg aagaggtttg aagtatctac agaaattggt agtctctctg ttgcttatca
     1261 aaagcaaaag aaagtgctag tttgtctaaa tggagcaggt ttgctaccaa gttatgaaaa
     1321 tttttcactt atacttgaaa aacctcctcc tacaattggt tatttgacaa ttgattttcc
     1381 gaacacaggt aggagtccga tttatgacca agctggaaaa aatctagata atcttgcaga
     1441 tgtggtttat gaagcacttg aagaattagg gatttctgaa tatatacttt gtgtacatag
     1501 ttggagtgga attttagctt gcaaattact cgagaaacca attaagtgtc agactttagt
     1561 agcaattgaa ccgacaacta aaaaagtcat gtttgctgat ttttcagaaa atccttatcc
     1621 agaaatggaa gagcagatga ggctgattga cgagtgtggt cctgaacttt attttaagaa
     1681 cttaactcaa gcaacattta gtcctgaaac gaataaaaaa atctgggaat taatgcaaga
     1741 aaaaggctta gagttggaaa atcaagatcc agaatttcag atatctggag agattactga
     1801 ggaagatttt gagaatttgt cgatagaatc tcatgtccct atatttattt tttgtcagac
     1861 ttatagagaa aaagagtaca gagaatcaga atattggact tccaatacta aactcatttt
     1921 aggagggaat caccattatt tacaatggtc agaatcggaa aaaattgcgg ctattattcg
     1981 agaattgtca gaataagatg gaaaaaagga gattacagga gacaagatga actactttaa
     2041 tgttgggaaa atcgttaata cgcagggatt acagggtgag atgcgagtct tgtctgtgac
     2101 ggattttgca gaagaacggt ttaaaaaagg agctgagctg gctttgtttg atgaaaaaga
     2161 tcagtttgtc caaacagtga ccatcgctag ccaccgtaaa cagaagaact ttgacattat
     2221 taaattcaaa gatatgtacc atatcaatac tatcgaaaag tacaagggat acagtctcaa
     2281 ggtcgctgag gaagatttga atgacctaga cgatggtgaa ttttactatc acgagattat
     2341 cggtttggaa gtctatgagg gtgatagctt ggttggaacc atcaaggaaa tcctgcaacc
     2401 aggtgctaat gatgtctggg tggtcaaacg aaaaggcaaa cgtgatttgc ttttacctta
     2461 tatcccacca gtggttctca atgttgatat tccaaataaa cgggtcgatg tggaaatctt
     2521 agaagggtta gacgatgaag attgatattt taaccctctt tccagagatg ttttctccac
     2581 tggagcactc aatcgttgga aaggctcgag aaaaagggct cttggatatc cagtatcata
     2641 attttcgaga aaatgctgaa aaggcccgtc atgtagatga tgagccctac ggaggcggtc
     2701 agggcatgtt gctcagagca caacctattt tcgattcctt tgatgctatt gaaaagaaaa
     2761 atccgcgcgt tattctcctc gatcctgctg gaaagcagtt tgatcaggct tatgctgaag
     2821 atttggctca agaggaagag ctaatcttta tctgtgggca ctatgagggt tatgatgagc
     2881 gcattaagac cttggtaaca gatgagattt ccctgggcga ctatgtcctc actggtggag
     2941 aattggcagc tatgaccatg attgatgcta cagttcgcct gattccagaa gtgattggca
     3001 aggagtctag ccaccaagat gatagttttt cttcaggtct tttagaatat cctcagtaca
     3061 cacgtcccta tgattatcga ggcatggtcg tgccagatgt attgatgagt ggccatcatg
     3121 aaaagattcg tcagtggcga ttgtacgaga gtttaaagaa aacctacgag cgcagaccgg
     3181 atttacttga acattatcaa ctgacagtag aagaagaaaa aatgctggca gaaatcaaag
     3241 aaaacaaaga ataaaggaga aacctatgca agtaatcaaa cgtaatggcg aaattgctga
     3301 atttaatcca gataagattt accaagccat cttgaaggca gcccaaactg tttatgtttt
     3361 gacagatgat ttgcgtcaaa atcttgctca agtcactaag aaggtagttt tggatttaca
     3421 agaagccaag gtggaacgtg cgactatcag tatgattcaa tctatggttg aacatcgttt
     3481 attgggcgca ggttacatta ccattgcaga acactatatt tcctatcgtt tacaacgtga
     3541 cttggaaaga agtggttatg gagatcatat cgcagttcat ttacattttg aacaaattcg
     3601 ctaagaaaaa gagtgggatg aagcaactac atctcactct ttcttaaatc tatttttttg
     3661 ggctgtttgg acagttgagg ggacaaatcg caggcgttga atatcgctta tacggataat
     3721 ccggctcaca tttttggaaa aatttttcac gataatttgc tggccttgct gatcatattt
     3781 gatgatatca cctgtaaagc ttgtctcaga caagataagg tgaacagcgg tttgtttctg
     3841 gatagcctct tcaatagtgg ctgtaaggga gttggtttca gtctggtcag gttggtcatg
     3901 tccatttaaa aaatcatgta ttttatctag aacttgctgg aatttatgtc tcatattggc
     3961 ctcccttctt ttatatcaat attatataaa attttcctaa aatctacaag attttacgaa
     4021 taaactaatg aaactaaaaa aggagaagaa aatggcagaa tttacatttg aaatcgaaga
     4081 gcacttgttg actctttctg aaaacgaaaa aggttggacc aaggaaatta accgtgtgag
     4141 ctttaatggt gcccctgcaa agtttgatat tcgtgcttgg agtccagacc atactaaaat
     4201 gggcaaaggg attactctct caaatgaaga atttcaaacg atggtggatg cctttaaagg
     4261 caactaatac tcttcgaaaa tctcttcaaa ccgcatcagc tttgccttgc cgtatgtatg
     4321 gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc agcctgcggc
     4381 tagcttccta gtttgctctt tgattttcat tgagtataag ttttcaaaat aaaaaaaagg
     4441 atattgagtc atgataactc ggtatccttt tttagttagt aaagtaagtc tgatttttaa
     4501 ggcgttgaag taggggacgg ctaataaaac taatagccag aagtttgcca aggtctggaa
     4561 tgataaaggg aagaaccccc acaacaagag ctttttcaaa tgccattcca gctaggaaat
     4621 gcaagctgag aatcccgccg acaaagacaa gggcatcacc caagaggttt gcaagaaaaa
     4681 tcttaacaac accactcttg ctgttggtta gagaggaagt aagtccagag taaacgagat
     4741 aaaaccaaag atagcctgca gtagggccaa ctaaagcctg aaaaccagct ccacctcctg
     4801 caaagacagg aagaccgata gcacctagaa gaagatagag tccagcagaa agtacagcct
     4861 ctctcggtct aaagacagta gcaatcaagc cgattgcaaa gttttgcaga gtgaagggaa
     4921 caggtccaat tggaagactg atttgtgcca aaacagcaat gagagcagcc ccaatagcag
     4981 ggatagcata aacgtgagct tttttcaaaa tagttaacct cttttctaat gtatagtaac
     5041 tattatactc atataggagt cgatgtcaac cattttttaa aaacaaggta acaaaaactg
     5101 taacagccga ttttcgtgac tagtcaagtt ggataatttt ttgttgattc gaaaatcatt
     5161 aaaaaagaag cagacatatt tatatcagct tcttttgttt cgattaacgc atggttacaa
     5221 attcttcaga tgaagttggg tgaatcgcta cagttgcgtc aaagtcagcc ttggttgctc
     5281 ccattttgat agcaacggca aatccctgaa tcatttcatc aacgccgtag ccaattccat
     5341 gaagtccgac aactttttct tctgaaccag ctgttatgag tttgaaacgg gattcttgac
     5401 ggttgcgagt gcaagcagag tacatagatg caaagcttga tttgtaaacc ttgatttggt
     5461 cttgaccgta ttctttaata gcttgctctt ctgtcaaacc aacagttccg atagcagggt
     5521 gtgaaaagac aacagttgga atagttgagt aatccatttt tgcagtagtt tttccgttaa
     5581 agagacgttc agatagggta cgtccggcct tgattgcaac tggagtcagt tctttctcgc
     5641 ccgttacatc acctagagca tagattccct caacaacagt attttggtat tcatccactt
     5701 ggataaagcc acgttcgttc agagtcactc cagctttttc aagttgcaag cccttaacgt
     5761 ttggacggcg gcctgtagcc cagataactt ggctagctgt gtgactagta ccatcttcga
     5821 aatgaatggt aatgccgtca gtagtttttt ctaacttgac agggactttg tgagtgtgaa
     5881 gtggtaagtt tgttctttcc atttccttga ccaaaccttc aacgatgtag gaatcaaaac
     5941 cacgtaaagg acgatcgcgg cgaacaaaga gatctgtctt gacaccaaaa gtgtggagta
     6001 cgccagctaa ttcaacggcg atataaccag cgcctagaat ggcaactgac tctggaagtt
     6061 cttcccaggc aaatacatca tcagaagagc cacctagctc agcaccagga atattaggaa
     6121 tacttggatg ggcacctgta gcaatcacga tatgtttagc acgaatcagt tcaccattta
     6181 cgcttacagt atgagaatct acaaattcag catgaccttc aatcaagtct acaccgttgc
     6241 gtttaaaact accatcataa gaagaacgag cgcgatcaat gtaggcttca cgattgcgac
     6301 gtagggttgc aaagttaaag ttaagatcag tagtcttaaa gccgtagtct tctccaaatt
     6361 gatggaaagt ctcagcgatt tgcgccccgt accacatgat ttttttagga acacaaccga
     6421 cgttgacaca ggttccacct aatttctttt cctcaataac ggctgctttg gctccatgtt
     6481 caccagcacg gttcatggta gcgattcctc cgctacctcc accgatagca atgatatcat
     6541 attctctcat tgaaaactcc tttgtaatct tttaaatagt agagtgtctt ttttgatagt
     6601 tatattttat tctttttttg atttgattgc aaaaatctgc tacgcacaaa aaattgcaaa
     6661 aaagcttgcc aaataagtca agatagtgta ttatatatct agtacaatag aaaagcaaaa
     6721 ttccgaacga ttgtttaatc ctgaactgcc attatttcca tctgaactgc attgtttgct
     6781 ggagggaaat ttggtataat agcaaagtat tgtaaaaaag aaaaggagtt tcattatgaa
     6841 gaaaaagaat ggtaaagcta aaaagtggca actgtatgca gcaatcggtg ctgcgagtgt
     6901 agttgtattg ggtgccgggg ggattttact ctttagacaa ccttctcaga ctgctctaaa
     6961 agatgagcct actcatcttg ttgttgccaa tgaaggaagc gtggcatcct ctgttttatt
     7021 gtcagggaca gtaacagcaa aaaatgaaca atatgtttat tttgatgcta gtaagggtga
     7081 tttagatgaa atccttgttt ctgtgggcga taaggtcagc gaagggcagg ctttagtcaa
     7141 gtacagtagt tcagaagcgc aggcggccta tgattcagct agtcgagcag tagctaaggc
     7201 agatcgtcat atcaatgaac tcaatcaagc acgaaatgaa gccgcttcag ctcaggctcc
     7261 acagttacca gcgccagtag gaggagaaga tgcaacggtg caaagcccaa ctccagtggc
     7321 tggaaattct gttgcttcta ttgatgctca attgggtgat gcccgtgatg cgcgtgcaga
     7381 tgctgcagcg caattaagca aggctcaaag tcaattggat gcaacaactg ttctcagtac
     7441 cctagaggga actgtagtcg aagtcaatag caatgtttct aaatctccaa caggggcgag
     7501 tcaagttatg gttcatattg tcagcaatga aaatttacaa gtcaagggag aattgtctga
     7561 gtacaatcta gccaaccttt ctgtaggtca agaagtaagc tttacttcta aagtgtatcc
     7621 tgataaaaaa tggactggga aattaagcta tatttctgac tatcctaaaa acaatggtga
     7681 agcagctagt ccagcagccg ggaataatac aggttctaaa tacccttata ctattgatgt
     7741 gacaggcgag gttggtgatt tgaaacaagg tttttctgtc aacattgagg ttaaaagcaa
     7801 aactaaggct attcttgttc ctgttagcag tctagtaatg gatgatagta aaaattatgt
     7861 ctggattgtg gatgaacaac aaaaggctaa aaaagttgag gtttcattgg gaaatgctga
     7921 cgcagaaaat caagaaatca cttctggttt aacgaacggt gctaaggtca tcagtaatcc
     7981 aacatcttcc ttggaagaag gaaaagaggt gaaggctgat gaagcaacta attagtctaa
     8041 aaaatatctt cagaagttac cgtaatggtg accaagaact gcaggttctc aaaaatatca
     8101 atctagaagt gaatgagggt gaatttgtag ccatcatggg accatctggg tctggtaagt
     8161 ccactctgat gaatacgatt ggcatgttgg atacaccaac cagtggagaa tattatcttg
     8221 aaggtcaaga agtggctggg cttggtgaaa aacaactagc taaggtccgt aaccaacaaa
     8281 tcggttttgt ctttcagcag ttctttcttc tatcgaagct caatgctctg caaaatgtag
     8341 aattgccctt gatttacgca ggagtttcgt cttcaaaacg tcgcaagttg gctgaggaat
     8401 atttagacaa ggttgaattg acagaacgta gtcaccattt accttcagaa ttatctggtg
     8461 gtcaaaagca acgtgtagcc attgcgcgtg ccttggtaaa caatccttct attatcctag
     8521 cggatgaacc gacaggagcc ttggatacca aaacaggtaa ccaaattatg caattattgg
     8581 ttgatttgaa taaagaagga aaaaccatta tcatggtaac gcatgagcct gagattgctg
     8641 cctatgccaa acgtcagatt gtcattcggg atggggtcat ttcgtctgac agtgctcagt
     8701 taggaaagga ggaaaactaa gatgcagaat ctgaaatttg ccttttcatc tatcatggct
     8761 cacaagatgc gttctttgct tactatgatt gggattatta tcggtgtttc atcagttgtt
     8821 gtgattatgg ctttgggtga ttccctatct cgtcaagtca ataaagatat gactaaatct
     8881 cagaaaaata ttagcgtctt tttctctcct aaaaaaagta aagatgggtc ttttactcag
     8941 aaacaatcag cttttacggt ttctggaaag gaagaggaag ttcctgttga accgccaaaa
     9001 ccgcaagaat cctgggtcca agaggcagct aaactgaagg gagtggatag ttactatgta
     9061 accaattcaa cgaatgccat cttgacctat caagataaaa aggttgagaa tgctaatttg
     9121 acaggtggaa acagaactta catggacgct gttaagaatg aaattattgc aggtcgtagt
     9181 ctgagagagc aagatttcaa agagtttgca agtgtcattt tgctagatga ggaattgtcc
     9241 attagtttat ttgaatctcc tcaagaggct attaacaagg ttgtagaagt caatggattt
     9301 agttaccggg tcattggggt ttatactagt ccggaggcta aaagatcaaa aatatatggg
     9361 tttggtggct tgcctattac taccaatatc tcccttgctg cgaattttaa tgtagatgaa
     9421 atagctaata ttgtctttcg agtgaatgat accagtttaa ccccaactct gggtccagaa
     9481 ctggcacgaa aaatgacaga gcttgcaggc ttacaacagg gagaatacca ggtggcagat
     9541 gagtcccttg tatttgcaga aattcaacaa tcgtttagtt ttatgacgac gattattagt
     9601 tccatcgcag ggatttctct ctttgttgga ggaactggtg tcatgaacat catgctggtt
     9661 tcggtgacag agcgcactcg tgagattggt cttcgtaagg ctttgggtgc aacacgtgcc
     9721 aatattttaa ttcagttttt gattgaatcc atgattttga ccttgttagg tggcttaatt
     9781 ggcttgacaa ttgcaagtgg tttaactgcc ttagcaggtt tgttactgca aggtttaata
     9841 gaaggtatag aagttggagt atcaatccca gttgccctat ttagtcttgc agtttcggct
     9901 agtgttggta tgatttttgg agtcttgcca gccaacaagg catcgaaact tgatccaatt
     9961 gaagcccttc gttatgaatg agatcaacaa gatggacact cgtctatctt gtttttgtat
    10021 ggatttccct atcgaaattc attaaaaatg tgatataatg aagtgttaga aaaacaggtt
    10081 tcatttgcct ggaaaggaaa aattatgtct gaaaaaaatt tttatattac aacgccgatt
    10141 tactatccat ctgggaaact tcatatcggt tctgcctaca caactatcgc atgtgatgtc
    10201 ctagcacgtt acaaacgcct gatgggctac gatgtatttt atctgacagg tcttgatgaa
    10261 catggtcaga aaatccagca gaaagcggaa gaagctggta ttacacctca agcctatgtt
    10321 gatggaatgg cggttggagt taaagaactc tggcaattac tagatatctc atacgataaa
    10381 tttatccgta caactgatga ctaccatgaa aaagttgtcg cacaggtctt tgaacgctta
    10441 cttgctcaag atgatattta cttgggtgaa tactctggtt ggtattcagt atcagacgaa
    10501 gaattcttta cagaaagcca gctggcagaa gttttccgtg atgaagctgg aaatgtgact
    10561 ggtggtattg ctccatcagg tcatgaggtt gaatgggttt ctgaagaatc atactttctt
    10621 cgccttagca aataccaaga ccgtttggtc gaatttttca aagctcatcc tgaatttatc
    10681 acgccagatg gtcgccttaa tgaaatgcta cgcaacttca tcgagccagg tttggaagat
    10741 ttggcggtat ctcgtacaac ctttacatgg ggagtgcctg tcccatcaaa tccaaaacac
    10801 gttgtctacg tttggattga tgcccttctt aactatgcga cagctcttgg ctacgctcaa
    10861 gacgaacatg gtaactttga caagttctgg aatggaacag tcttccatat ggtaggaaaa
    10921 gatatccttc gcttccactc tatctactgg ccaatccttc ttatgatgtt ggatgttaaa
    10981 ttacctgatc gtttgattgc ccatggttgg tttgtcatga aagacggaaa aatgtctaag
    11041 tcaaaaggga atgtcgttta ccctgaaatg ttggtagagc gttatggact agatccactt
    11101 cgttactacc tcatgcgtaa ccttccagtt ggttcagacg gaacctttac tcctgaagac
    11161 tatgttggcc gtatcaacta tgaattggct aatgaccttg ggaacctcct taaccgtacg
    11221 gtttccatga ttaataagta ctttgatgga caaatccctg cctatgtaga aggtgtgact
    11281 gaatttgatc atgttcttgc tgaggttgca gaacaatcaa tcgcagactt ccatacacac
    11341 atggaagcag ttgactatcc acgtgcgctt gaagcagtct ggactctgat ctctcgtacc
    11401 aataaataca tcgatgagac cgcaccatgg gtcttggcca aggatgaagc tcttcgtgac
    11461 caattggcaa gtgtcatgag ccacttggca gccagcattc gtgtagttgc tcacttgatt
    11521 gaaccattta tgatggaaac tagtcgtgca gttttgactc aacttggttt ggaagaagtt
    11581 tctagtcttg aaaacttgag tttggctgac ttcccagcag atgtgactgt agttgccaaa
    11641 ggaacaccta tctttccacg tctaaatatg gaagaagaaa tcgcctatat caaggaacaa
    11701 atggaaggca ataaaccagc agtcgaaaaa gaatggaatc cggacgaagt tgagctcaaa
    11761 ctaaacaagg atgaaatcaa gtttgaagac tttgacaagg ttgaaatccg tgtggcagaa
    11821 gtcaaagaag tgtctaaagt agaaggttca gataagttgc ttcaattctg cttggatgct
    11881 ggtgatggag aagatcgtca gattctttca ggaattgcca aatactatcc aaatgaacaa
    11941 gaattggtcg gcaagaaagt tcaaatcgtt gctaacctca aaccacgtaa aatgatgaaa
    12001 aaatatgtca gccagggtat ggttctctca gctgaacatg atggcaaatt aacccttctc
    12061 acagttgatc cagctgtacc aaatggaagt gtgattgggt aaaagtagac aggactagtt
    12121 caggctagtt ctgttttttt atttatactc aatgaaaatc aaagagcaaa ctaggaagct
    12181 agccgcaggt tgctcaaaac acagttttga ggttgt
//
LOCUS       DAVHSH010000054        12199 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000054 DAVHSH010000000
VERSION     DAVHSH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.055"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(376..1569)
                     /locus_tag="VVR08_001693"
     CDS             complement(376..1569)
                     /locus_tag="VVR08_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU6075577.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(1707..3149)
                     /gene="gtfA"
                     /locus_tag="VVR08_001694"
     CDS             complement(1707..3149)
                     /gene="gtfA"
                     /locus_tag="VVR08_001694"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU6075578.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(3426..3506)
                     /locus_tag="VVR08_001695"
                     /pseudo
     CDS             complement(3426..3506)
                     /locus_tag="VVR08_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3507..4340)
                     /locus_tag="VVR08_001696"
     CDS             complement(3507..4340)
                     /locus_tag="VVR08_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6075579.1"
                     /translation="MKQDERKALIGKYILLVLGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            complement(4354..5220)
                     /locus_tag="VVR08_001697"
     CDS             complement(4354..5220)
                     /locus_tag="VVR08_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6075580.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(5234..6493)
                     /locus_tag="VVR08_001698"
     CDS             complement(5234..6493)
                     /locus_tag="VVR08_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6075581.1"
                     /translation="MEWYKKIGLLVTTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFAIATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(6585..8747)
                     /locus_tag="VVR08_001699"
     CDS             complement(6585..8747)
                     /locus_tag="VVR08_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6075582.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            8855..9715
                     /locus_tag="VVR08_001700"
     CDS             8855..9715
                     /locus_tag="VVR08_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6075583.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVNLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            9712..10647
                     /locus_tag="VVR08_001701"
     CDS             9712..10647
                     /locus_tag="VVR08_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU6075584.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKA
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(10773..10860)
                     /locus_tag="VVR08_001702"
     tRNA            complement(10773..10860)
                     /locus_tag="VVR08_001702"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10824..10826),aa:Ser,seq:gct)
     gene            complement(10867..10940)
                     /locus_tag="VVR08_001703"
     tRNA            complement(10867..10940)
                     /locus_tag="VVR08_001703"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10904..10906),aa:Ile,seq:gat)
     gene            complement(10976..11046)
                     /locus_tag="VVR08_001704"
     tRNA            complement(10976..11046)
                     /locus_tag="VVR08_001704"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11012..11014),aa:Gly,seq:tcc)
     gene            complement(11066..11138)
                     /locus_tag="VVR08_001705"
     tRNA            complement(11066..11138)
                     /locus_tag="VVR08_001705"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11103..11105),aa:Phe,seq:gaa)
     gene            complement(11142..11215)
                     /locus_tag="VVR08_001706"
     tRNA            complement(11142..11215)
                     /locus_tag="VVR08_001706"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11179..11181),aa:Met,seq:cat)
     gene            complement(11226..11315)
                     /locus_tag="VVR08_001707"
     tRNA            complement(11226..11315)
                     /locus_tag="VVR08_001707"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11277..11279),aa:Ser,seq:tga)
     gene            complement(11326..11399)
                     /locus_tag="VVR08_001708"
     tRNA            complement(11326..11399)
                     /locus_tag="VVR08_001708"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11363..11365),aa:Ile,seq:cat)
     gene            complement(11413..11486)
                     /locus_tag="VVR08_001709"
     tRNA            complement(11413..11486)
                     /locus_tag="VVR08_001709"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11450..11452),aa:Met,seq:cat)
     gene            complement(11492..11565)
                     /locus_tag="VVR08_001710"
     tRNA            complement(11492..11565)
                     /locus_tag="VVR08_001710"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11529..11531),aa:Pro,seq:tgg)
     gene            complement(11581..11654)
                     /locus_tag="VVR08_001711"
     tRNA            complement(11581..11654)
                     /locus_tag="VVR08_001711"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11618..11620),aa:Arg,seq:acg)
     gene            complement(11664..11749)
                     /locus_tag="VVR08_001712"
     tRNA            complement(11664..11749)
                     /locus_tag="VVR08_001712"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11713..11715),aa:Leu,seq:taa)
     gene            complement(11757..11828)
                     /locus_tag="VVR08_001713"
     tRNA            complement(11757..11828)
                     /locus_tag="VVR08_001713"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11794..11796),aa:Gly,seq:gcc)
     gene            complement(11851..11923)
                     /locus_tag="VVR08_001714"
     tRNA            complement(11851..11923)
                     /locus_tag="VVR08_001714"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11888..11890),aa:Thr,seq:tgt)
     gene            complement(11942..12023)
                     /locus_tag="VVR08_001715"
     tRNA            complement(11942..12023)
                     /locus_tag="VVR08_001715"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11987..11989),aa:Leu,seq:tag)
     gene            complement(12029..12101)
                     /locus_tag="VVR08_001716"
     tRNA            complement(12029..12101)
                     /locus_tag="VVR08_001716"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12066..12068),aa:Lys,seq:ttt)
     gene            complement(12126..12198)
                     /locus_tag="VVR08_001717"
     tRNA            complement(12126..12198)
                     /locus_tag="VVR08_001717"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12163..12165),aa:Asp,seq:gtc)
BASE COUNT         3863 a         2700 c         2176 g         3460 t
ORIGIN      
        1 tactatgtct tttcacacca accttattcc gaattcaatt acttttgtga tttacatata
       61 tagattaaga ctatctttta tactttaaaa tttctcgcta ccttatccac tatatgctcc
      121 tcgctatcac gtttctattc atagcctacg atttcactat tgctttctct gacaattctt
      181 atttcctgcg tcagacttaa aacgatctat ccccagacca ttttaatccg ctacctcacg
      241 atagtcaggc ttggggagcg ctattgtatt caccggtagt ggatccctac agaggactta
      301 cacctcagat gcacgacatg cccatcgtat aaaaaaatct cctacccaag gtagaagatt
      361 tcaaacttat aaaacttaat ccgtcatgtc cgataccaac attcgatgct ccaatggaat
      421 actgcacata actagcaaga aaataaagcc tgactgaatc cagaagagag ccaagtcaaa
      481 aattccgtgc acagcaacca ctgtaaggaa agatagataa aggccgataa tcggacgttt
      541 ccccgactcc tgactcatat ccatcatcaa gcgaacagga gcaacagaag acaaaactaa
      601 taaaatggta cccacaattc cgtaactcag aatcgtatca atataaagac tgtgggcatg
      661 ttcatgataa ggagcatgta tccgaggata agagtgcata taggtcaatg gcccttcacc
      721 ccaaaaagga ttttgcttaa acaaggccat cccagcatcc cagatagaaa tgcgttcttc
      781 catagaagag tctaaagtac ccattcgaac tcccaaatca ctagaaaaga ggaaactcaa
      841 accaatcgcg aagaccccaa tactaagcca aaaggccttc cagtttttaa tagtcgtaaa
      901 gagatagata attgctccag cgataatagc aggaaaggca gttcgatttt gagtaaagtt
      961 caaaccaaag agattaacaa agcctgcaat cacacagaat actttcaacc aattcaactt
     1021 ggtcgttgta aacagataga aagcaatcat aatacagaaa caacaaataa ttccataata
     1081 attaggatta aagaaggtca cttctgcccg gttctgatgc cacacctgca tattgggtga
     1141 aagaaaagca tagttaaatt tcttcacaat ttggaaatgt tctaaactgg caaaagcagc
     1201 tgacaagaca ctaccaaaca agacgaactg caaaatcaat cgaaagaatt tatgggataa
     1261 aatcgactga tagtgcaaaa agaaaatagt aaatagaaac attcctactg aagccacaag
     1321 acccatccaa ttttgtgcaa gaatggatat aacagtacta tagctaagaa aaagaagcag
     1381 catcggatgc tcccccattt tctgaagaat acttttcatg tctcctgtaa aaatcaaact
     1441 gataatatat aaacagagta caactacaaa aagataaaag ggtaaaaaga tacttaggat
     1501 aattcccaat aaaatcagct ctttactaga caaccccttc agcttttcaa taaagcctat
     1561 tgatttcaaa atgaatcctt tctctccaaa tcagctgatt cagataatag taagctatcc
     1621 tatattgtac cactttttta gcaatttgaa aacaaaggaa acgttttcca aaataaaaac
     1681 cctattttat ccaccatatc aaggcttcaa aatgatactt caactccatt ctcaattacc
     1741 cgataagtct gattttgcaa atcaatttct actactgctg ttacggactt atctttattt
     1801 tgacgtttga ttacaatgct gtgagctgtt ggtgtctcta tctcagtagt cccttctaga
     1861 tcaaaggctt ctgaacggtt acggaaagaa aatagattga gaagggcctt cacaacaggt
     1921 cgttgcactt cttttgctat ttcctcgttg ctatagtaat gacgattaat atttcgacct
     1981 tctttagttt cttctaataa tttcaagtca ttcttgcctg ctaatagacc cacatagtaa
     2041 acctgaggaa tacctggggc aaaagcttga attagacgag cgagaaaata cttgacatca
     2101 tcatctccaa gcgctgaata gtaggttgaa ttgatttggt agatatctaa gttgttatac
     2161 tcggcactag agtacttacg tttgacattg gctccaacct tatagagttc atttgaagca
     2221 tagtcaatct cctcatcggt caggatatcc ttgacatcta ctactccaat cccatcatgg
     2281 gtatctagcg tcgtaaattg cttcatcggg ctcatcttta accacttagc caaacgctct
     2341 gttctggaac tgtaaagagt ataaagtgtc accattggaa gagcaaaatc ataaacatag
     2401 taatcatggt ctgctatttt aaactgaatc gaatagtgtt catgaatctc aggtaaaagc
     2461 tctgtcccat actcggcagc gatatctcga actttgtcca ataaatccca aatatctggt
     2521 tccacaaaga aatcattagt atccaatttc ttcactgcat aagcaaaggc atctagacga
     2581 atcaaatcac acccattact tgccaagtgc tgaatggtct tacggataaa ttccatagtt
     2641 acttctttgg tcacatcaag atcaatctgc tcctcaccaa aggtattcca caaatgttcc
     2701 actgaaccat cttcaaacac aatctcttgc tttggtgcac gatccttacg cttgtaaatt
     2761 aaatctacat cagactgtgt cggacggttt tctggccaaa acttatccca gtttaaaaag
     2821 agatctttaa attcactggc ttcatgtttt tcttgatagt ccttataata cttggattga
     2881 cgagaaatat gattaatcat aaaatcaaac ataagataat atctctcacc taaacgctta
     2941 acatcctccc aatcaccaaa agctgagtcc acttcgtcgt agtcaactgg cgcaaatcca
     3001 cgatcacctg ttgatgggaa aaatggtaaa aggtgaactc ctccaatagc atctccaaaa
     3061 tgctcttcca aattatcata taagtcttta agattatttc caaggctatc agaataggta
     3121 atcaacatgg ttttattttg aattggcatc attactctcc tttttctaat tgaagccaag
     3181 tctcatatga tctggcttcg taaatcaaat tcattttaaa tctctattta tcatcaaact
     3241 cgtactaata tagactgtga taaacaaagt actactttct tgttttctac atagaattat
     3301 caacaagctg aactcttcct ctgtgtcaaa gactatagat tccatgagct cttcttatac
     3361 tattcgaaaa tctcttcaaa ccacgtcagc gtagccttac cgtaggtatg gttactgact
     3421 tcgtcagttt catccacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta
     3481 gtttgctctt tgattttcat tgagtattac ttcactgccc cgttgcttat tcctgcgatg
     3541 atatggcgtt ggaagaagag atagacaatg gtgatactga taatgccgac cacgtaagag
     3601 gcaaagcttg gtccgtagtc gttgaaatat tggcctgcgt agttgtattg gaacaaaggc
     3661 agagtccaca ttttggaatc ccggttcaag acaaggagtg gcaacatgaa gtcattccag
     3721 aaccaaaggg cattgatgat catggttgtc gcatgcatcg gtttcatcat tgggaagatg
     3781 atgcggaaat aggttgtaaa ttgattagcc ccatcgatct ctgctgcttc atccagactt
     3841 tctggaatcg agattttgat atagccaaca tagagaaaga gggtctgtgg aatcgcatag
     3901 gtcaagtaga gcaagatcaa accaaaggta ttagccaaac cgagtttact catcataacc
     3961 gtaatcggaa tcatgatgac ttggaaaggt acgaatattc cgaggattaa gagggtatac
     4021 atgatggtaa aggcttttct tttactcata ttgcgagcga tggagtaggc tgccataggg
     4081 ataaagatca ttactgcaag taaagacaag acagtgatga cgacagagtt ccaataatag
     4141 cctccaatcc catcagctaa gagacggcta aagttgtccc atgtgaagtt ggttggaaag
     4201 ccaaagaaat tatctacaat atccttagtg ggtttgaagg aactaaagag ggtagcaagg
     4261 agcggcacta aaatcagaac cgatcctaga accaatagaa tgtatttgcc aatcagggct
     4321 tttctttcat cttgtttcat catgcttctc ctcttaaatt tcaaatttct tagatactct
     4381 caattggatg atcgaaatca ctacaattaa gaggaacaag attacggcaa tggcattggc
     4441 ataaccgaat tggttgtttt taaaggcata gttataaacc aagagcccaa gtgaggttgt
     4501 ggcattgttt ggaccaccac cggtcatggc aaagacttgg tcaaaggcag tcagcccacc
     4561 ttttagggct aggataaaga ccatagagac acttggtagc aagtaaggca attcaatgtt
     4621 ccagaaaact tgcttgctag tcgcaccatc aatccttgct gcctctgtaa tctcagttgg
     4681 aatagattgc aaaccagcta ggaagatgat gatgggcata gccacccctt gccaaagaag
     4741 gacaaaggca gccgcaaaga ttgctcccca cttagtccct aaaagactgg tttggagaaa
     4801 ttcaatatga agggcattcc caatcgctgg aagaccgtag ttgaagactt gcttgaagat
     4861 caaagccact gtcaaaccag ataaaacagc tgggaagaag aaccaagcac ggaagaaggt
     4921 ttggcctttg attttagaat tcaagacacg cgcaatgaag atcccgagtg caatctcacc
     4981 aaccaccatg gcaatcgtaa tgattgcggt aaagccaatc gcattcatga attttggatc
     5041 catgaagagg agcttaaagt tgtttaagcc aacaaatttg tagttataag tcaatcctgt
     5101 ccagttggta aaactgtaaa aggctccttg aaacatcggc acatagaaga aaattgcttg
     5161 taacaagagg gggatgacca caaaagccca tgcccaatat ttttgtaata cttttttcat
     5221 agtctctcta ctcctaatcc acatccgctt tcatcgggtt aaagaaggca ttcaaatcat
     5281 tgaccatgcc ttgtttatca ccggtcaaga catagttcat ggtcaaggta tggaagtctg
     5341 cttcactggt ccagtattgt tgcaaccaga ccaagtgacg atccgtaaag gcatattcgg
     5401 tcataccagc aagcggtgaa tcttctcctg cttgtttgac cccttcgatc gctgttggag
     5461 atccgtccac atcgtagtat ttttgcatga cttctggacg ggtcatatat tccacaaagg
     5521 cattggcttc ttttggatgt ttggtggtgg ctgagataga ccatgccaag tctcccgcac
     5581 caacggttaa gctttgtcct ttttcttttc ctggaatcat gaaggtccca atcttaaagt
     5641 tcggtttttg ttcattaatc gctgtgatcg cccaagaccc atttggtgtc atgaggacat
     5701 ccccacgtgc gaaggctccg ataacatcgg tatagccagc accttcccag ttcttttgct
     5761 tagagccatt gatgcgaagg atgtccatga ccttgatatc atctttcata atcggatccg
     5821 acaatttaat ggcatttggt tgagaataac gaaggtattg atttgcttct tttcctccac
     5881 ctgttgctat cgcaaaggct aattgattgt aaccattgag tgtccaagca tctgcacctg
     5941 caattccaaa tggtgtttgt cctttagcaa cgatatcttt gactaactgt tcaaattcat
     6001 cccaggtttc aggaaccttc aagcccagtt cttcgaattt atctttgttg tagtaaattc
     6061 cataagcatt agctgtaaaa ggaacgttgt aaactttttc gtttacagca tatttttcag
     6121 cgtagccatt tttcacgcgt ttcaggtagt ctttgttgct caaatcttca aagacacctg
     6181 cttttgccca ttcttgcagt tcgatggact gtgggtaaat attgaccaca tcaggcacat
     6241 ctcctgcgag aacgcgtgtc ttcaatactt caccagcatt tggtacattg acgactttga
     6301 ccttgatctt agggttttcc ttctcaaaat cacgagtgat ttcttccaag gttttggtca
     6361 tttctttttt ctggttgaaa tactcgatgg tcactgtgcc atccgcagat ttaccatagt
     6421 tggagcaagc gccgagccca accaaagcta aacctgtagt tacaagaagt ccgatttttt
     6481 tataccattc cattagaaag cctcctttat aaatttatac acccttattg aactgcaccc
     6541 caaaagttag acagaataaa tctaactttt ggggtcagta catatcatag ttttctaaaa
     6601 atatactgtc tactcaaaaa atctccttgg gataagataa cagttaagcc cgcatacatt
     6661 agttctgcac ctgagtaaac ttcgccattt tcctgtaatt tatatagtcc ctcttcatcc
     6721 aaatctttta attttaaagt tgtttccatg gtctctacaa cagataaaac gcgaacgtag
     6781 gttacaatcg tttgatttcc gtaattaaat tgtacagctg cttcattgga tgcagtatca
     6841 ggattaatta gtctatactg ctgtcctaac tgaactactg gtcgtaattc tttatacaag
     6901 ttcacctgat tagcaatcgt agctttctct tcatctgata aatttgtcaa atcaagctca
     6961 tagcccaaat ttcccatcat tgctacatgg ccacgtgttt ctaatggtgt cattcgtccc
     7021 atctgatgat tcggtactgc tgacacatga gcccccatag aaatggttgg atagagatag
     7081 gatgaaccgt attgaattgg taaacgtgca atggcatcag tattatcact agcccagact
     7141 tgtgggaaat agcgtatcat accaagatca tttcgtccac caccaccaga gcaggactca
     7201 aagagaatat ggctgtgctt ctctgtcaga taagaaacga gttcgtaaag ccccagcatg
     7261 tactgatgag attgcatctg tgtctctaga taagttaatc cattccctag cttagtgata
     7321 ttgcggttca tatcccattt aatgtaatca atctcatgat aagataggag ttgatctaag
     7381 acacttttca agtattctac tacctgagga ttggcaagat taagtactaa ttgattccga
     7441 gaataagtat gctcataatc aggaacctga atagcccagt caggatgttg acgatacaaa
     7501 tcactatcta cagaaatcat ttcgggttct aaccaaagtc caaactgcaa acctctttca
     7561 tggatagctg aaatcagact ttctagactt ccacccagtt tttcctcatt aacaacccaa
     7621 tcacctaaag cacgattatc atcaaaacga ttgccaaacc aaccatcatc taatacaaaa
     7681 agttcaatgc caactttctt agcttcatct gctaactcta acagtttttc tctctgaaag
     7741 tcaaagtaag tagcttccca gttattgatt agaattggac gttctttttt agaaaattca
     7801 cttagaataa tgtgcttcag tacaaaattc tgactttcat gactaatacc agttaatccc
     7861 tgatctgaat gagtcactaa agctaccggt gtttcaaagt attcctcagg ggctaacttc
     7921 caagaaaagt tttctggatt aatgccaata gccacccgaa cttcattcaa ttgatttttt
     7981 tgaacaaaag cttcaaagtt gccactatac attagttgaa tagcaaacac attcccagca
     8041 tcctctgtga ctccttgttc gcatagtaga agagctggtg tttgagcatg accagaagca
     8101 cctcggtttg aactaatcga aaagattcct tgttctacct gttgacgtct aacagtcttt
     8161 tcacgagcat aagcaccctg cagagttact atttcgtaat ctgcagctgg aaaatcagcc
     8221 ataaaagaaa aatctttata gatgacaact tcctgattac tattattatc taatttactg
     8281 tagctagcaa tagtcgcatc attattaaaa gtagtataat acaaagtcag actaagttga
     8341 gccttagaat cttctaacat taagacaaga gtctctgtat cgtccatgct atgtggagaa
     8401 ggtaagccct gtggaccatt ctgacctttt aaaatctttg cttctacaaa tcgaaagtct
     8461 gttacttcag ttacattatg ctgaacctgt atggttggtt tcctaaaatc tcctaagcca
     8521 tgttgtccaa aaatttgacg ttgagtatct aaactaaagg ttcgattagt agccgttgga
     8581 tttcctgaaa aggcatggtc tcgttcataa acactattgg aacctttata gttcttaata
     8641 gtctttccta aatgtttcaa aagtaagtag ccatttcgat tttcaataat caaacttaga
     8701 tttttactct caacataaaa tagattattc tctatcctaa ctcccattta cttcacctca
     8761 tcactttatt gattatattt tatcacctga aatcgctttc caaaatagaa aaatgtctca
     8821 agaatatggt aaaatgttag gtaggaggta gcacatgtta gttttttcag aatatcagac
     8881 tggaacaatc gaccttgccc taagctttta tggatatgag gaatgcacac ctaattactc
     8941 ttttggtcca gccattcgtg atacatacgt cctacattac attactaaag gacaaggaaa
     9001 atttcattac aagggtaaaa ttgttaattt aaaagaagga gatttctttc tattaaaacc
     9061 agaggaacta accttttatc aagcagatag taaagaacct tgggcctact actggttagg
     9121 aatcactgga gggaaatccc ctgattattt tgctctttct caaatttctg atcaatccta
     9181 tctcatccaa tctgaaactt gtcataccca gactactgca aaactcatct cagacattgt
     9241 ccgcttcgct cagattacaa aatcaagtga attagctcaa ctccatatca tgggacaact
     9301 tcatgaactg atgtttcatc tgggaactat tgctcccaat cagaaaaaaa agaatatttc
     9361 atcaacccac caactctatc ttgaatgcaa acgattaatt gatagccact atcctcaatc
     9421 acttacaatt caagatttag caaaagaact atccgttcac agaagctact tatcaagcgt
     9481 attcaaagaa tttaatacct tatcacccaa agaataccta ctctacgttc gaatgcaccg
     9541 agctagacaa cttctcgaaa atacccaaga gtccatcaag gtaattgcat actcggtagg
     9601 tttttcagat ccactccatt tttcgaaagc ttataaacaa tactttaatc agactccaag
     9661 tcatacaaga aaagaatact ctcaatacca actagtgaga aaggcaacat tatgaaatcc
     9721 taccaagctg tctaccaaat cctatctaaa gaaaccgact atatcagcgg agaaaaaatc
     9781 gcagaaaaac tatccctaag ccgaacatca atttggaaag ctatcaagcg actagaacaa
     9841 gaaggcattg aaattgatag tatcaaaaat agaggatata aactaatgaa tggtgacctt
     9901 attcttccag agattctaga agaaaatctt ccaattaaag tcagctttaa acccgaaaca
     9961 aaatcaacac aactagatgc aaaagaagca attgatttag gccatgaagc aaataccctc
    10021 tatctagctt cctatcaaac agcaggccga ggccgttttc aacgttcctt ctactcacca
    10081 caaggtggta tttatatgac actccatctt aaaccaaatc tcccctatga caaattacca
    10141 tcctacacac tacttgtagc tggagctgtc tacaaagcca ttaagaacct aactttaata
    10201 gatgtcgaca taaaatgggt caatgatatc tatctaaaca atcataaaat tggaggaatc
    10261 cttactgaag caatgacctc tgtagaaact ggcttagtca cagatatcat tattggagta
    10321 ggtatcaatt tcactattaa agacttccct caggaattaa aagcaaaagc tgccagctta
    10381 tttaaagcta cagctcctat aacaaggaat gaattgatca tagaaatctg gcgtgctttc
    10441 ttcgaaacac cagcagaaga gctattatac ctatacaaaa aacagtcatt cattctagga
    10501 aaagaagtca ctttcacact agagcaaaaa gactacaagg gacttgctaa agacatctca
    10561 gaaaatggaa aacttttaat tcaatgtgat aacggaaaag aaatctggct aaatagtggc
    10621 gaaatttctc tcaatagttg gaagtaaaat aacacaatta taatataaac gatataaaaa
    10681 taacttcaga ttagtaattc aattaagttt tacggatctg aagctttatt gtctctaaaa
    10741 ataaaaaaga gagttacaaa ctctcattaa aacggagaat aagggattcg aacccttgcg
    10801 ccagttaccc gacctaacga tttagcaaac cgtcctcttc agcctcttga gtaattctcc
    10861 aattaatggg cacgagtgga ctcgaaccac cgacctcacg cttatcaggc gtgcgctcta
    10921 accacctgag ctacgcgccc aagttaaaaa acttggtaat ttgaacaaag ttcaaagcgg
    10981 gtgacgagaa tcgaactcgc gacaacagct tggaaggctg tagttttacc actaaactac
    11041 acccgcataa atactatcaa taaaatggcg cgagacggaa tcgaaccgcc gacacatgga
    11101 gcttcaatcc attgctctac caactgagct accgagcctt attgcgggag caggatttga
    11161 acctacgacc ttcgggttat gagcccgacg agctaccgag ctgctccatc ccgcgttaat
    11221 ataaaaggag gatgtgggat tcgaacccac gcacgctttt acacgcctga cggttttcaa
    11281 gaccgttccc ttcagccgga cttgggtaat cctccaatat tcaaatggac cttgtaggac
    11341 ttgaacctac gaccactcgg ttatgagccg agagctctaa ccagctgagc taaaggtccg
    11401 acaagatcat tatagcggcg aaggggatcg aacccccgac ctcccgggta tgaaccggac
    11461 gctctagcca gctgagctac accgccatga atcgggaaga caggattcga acctgcgaca
    11521 ccttggtccc aaaccaagta ctctaccaag ctgagctact tcccgagtta aatagaaaaa
    11581 tgcaccctag aggagtcgaa cctctaaccg cctgattcgt agtcaggtac tctatccagt
    11641 tgagctaagg gtgctccata ttatgccgag gaccggaatc gaaccggtac gatcgttacc
    11701 aatcgcagga ttttaagtcc tgtgcgtctg ccagttccgc caccccggcc tctctaagcg
    11761 aacgacggga ttcgaacccg cgacccccac cttggcaagg tggtgttcta ccactgaact
    11821 acgttcgcac tgttttcttc tatctaaaaa tgccggctac atgacttgaa cacgcgaccc
    11881 tctgattaca aatcagatgc tctaccaact gagctaagcc ggctcatttg ttatatctta
    11941 atgcgggtta agggacttga acccccacgc cgttaagcgc cagatcctaa atctggtgcg
    12001 tctgccaatt ccgccaaacc cgcatatatg acccgtactg ggctcgaacc agtgacccat
    12061 tgattaaaag tcaattgctc taccaactga gctaacgagt ctaaaataac ttgcgttacc
    12121 ttaaacggtc ccgacgggaa tcgaacccgc gatcttcgcc gtgacagggc gacgtgataa
    12181 ccgctacact acgggacct
//
LOCUS       DAVHSH010000055        11389 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000055 DAVHSH010000000
VERSION     DAVHSH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.056"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            713..1705
                     /locus_tag="VVR08_001718"
     CDS             713..1705
                     /locus_tag="VVR08_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6075585.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VVR08_001719"
     CDS             1707..2525
                     /locus_tag="VVR08_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU6075586.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VVR08_001720"
     CDS             2527..3312
                     /locus_tag="VVR08_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075587.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLILISLVFFVISLKLWDKGLDSYESAGS"
     gene            3410..3628
                     /locus_tag="VVR08_001721"
                     /pseudo
     CDS             3410..3628
                     /locus_tag="VVR08_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
     gene            3565..3810
                     /locus_tag="VVR08_001722"
     CDS             3565..3810
                     /locus_tag="VVR08_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6075588.1"
                     /translation="MSRRKKAYQGRKIGSQLLATLESEAHKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
     gene            complement(4236..4310)
                     /locus_tag="VVR08_001723"
                     /pseudo
     CDS             complement(4236..4310)
                     /locus_tag="VVR08_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4543..10947
                     /locus_tag="VVR08_001724"
     CDS             4543..10947
                     /locus_tag="VVR08_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU6075589.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSQDTEEKKTTIIEEKEVVSKTPVIDTKTSNEENSNKSQGDHT
                     DSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIFNGSAIE
                     TIPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGKNFDGR
                     GMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGG
                     KITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYKMYSDA
                     GSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGIPMVVA
                     TGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDKVNIGG
                     ESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRI
                     YTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVFSISGD
                     DGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFA
                     PDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTYGYMSG
                     TSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARPMMDAT
                     SWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKEIKGDK
                     KYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPEIHPEK
                     VKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEALNSNG
                     KKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPGTLNKG
                     IGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIANIYPLD
                     SNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFIRGILN
                     SKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQFEPIAE
                     GQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYHKVKDQ
                     YKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQGRNRKL
                     DKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISYYLVDPD
                     QDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSFTIDRNI
                     STIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAYDDGSALQYE
                     TEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATKYDSHS
                     KTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEYPYVSS
                     YGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNP
                     GKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDG
                     FNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDG
                     SMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVD
                     NYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYS
                     DLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSVEYADGKSVVFNINDKRNNGFDGEIQE
                     QHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSELKPHR
                     VTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVINLSK
                     DTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSD
                     STKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKN
                     QD"
BASE COUNT         3957 a         1712 c         2289 g         3431 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattaatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttacaaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 gggtttaggt agtcggtgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct atggtgagaa gatgagtaga
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttca tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcattctgtt ttttattgga ctataatagg
      601 ttggtataaa gccttctgta gtaataaaat gtagaaggtg tagaaagtaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaacattt tgtgaagatt gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccaa actcgctctt tcataagcgc atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagattaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccgttt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtcc
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat attgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa ggcagttgtc gctgaggttt tgaaggattt
     3421 gccagaatgg tttggaatcc cagaaagcac ataagcctat ataaaaggaa ccacgacact
     3481 gcaagtttgg accgcctatc aggagagtga tttgactgga tttgtaagct tatcctattc
     3541 gagtgaagat tgtgcagaga ttgattgtct cggcgtaaaa aagcttatca aggtagaaaa
     3601 attgggagcc aattgcttgc tactttagag agtgaagctc ataaaaaagt tggttatctg
     3661 caggtcaaaa cagtggcaga aggttctaat aaagattatg atcgaacaaa tgacttttat
     3721 cgaggtcttg gctttaaaaa gttagagatt tttcttcaac tatggaatcc gcaaaatcct
     3781 tgtcagattt tgattaaaaa gcttgaataa tattacttga catctattct cagagtgcta
     3841 tactgtaagt gtaatcgccg atttagctca gttggtagag caaggcactc gtaaagccta
     3901 ggttataggt agataaacga ctgaggattt gaaaaaatag ataggtagaa gataaccgtt
     3961 aagccttatt cttagcggtt atttatattg tttaatagcg ctgatatttc atcaattatg
     4021 cctgttttcg tgtttctggt agttgttcaa gtttattgct actatttttg atggtatgaa
     4081 tgtgcttata atgtatcccg gttaacgaaa gttttggact tatactcttc gaaaatctct
     4141 tcaaaccacg tcaacgtcgc cttgccgtgc gtatggttac tgacttcgtc agttctatcc
     4201 acaacctcaa aacagtgttt tgagctgact tcgtcagttc catctacaac ctcaaaacag
     4261 tgttttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtactaa
     4321 tcttattttt taatgtgtgc taaaaaataa attaatgcat gttaattttt cttgaattaa
     4381 atttttttaa atgatatact gtttttatgg agagataaca attatatata aatgtactac
     4441 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
     4501 ttattatcta ttggaagtta tataaatatg taaggaatta aaatgaaaaa aagtacagta
     4561 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
     4621 gcagacacat ctagctctga agatgcttta agcatctctg ataaagaaaa agtagcagaa
     4681 aataaagaga aacatgaaga tatccatagt gctatggaaa cttcacagga tactgaagaa
     4741 aagaaaacaa caattattga ggaaaaagaa gttgttagta aaactcctgt gatagacact
     4801 aaaactagca atgaagaaaa ttccaataaa tcccaaggag atcatacgga ctcatttgtg
     4861 aataaaaaca cagaaaatcc caaaaaagaa gataaagttg tctatattgc tgaatttaaa
     4921 gataaagaat ctggagaaaa agcaatcaag gaactatcca gtcttaagaa tacaaaagtt
     4981 ttatatactt atgatagaat ttttaacggt agtgccatag aaacaattcc agataacttg
     5041 gacaaaatta aacaaataga aggtatttca tcggttgaaa gggcacaaaa agtccaaccc
     5101 atgatgaatc atgccagaaa ggaaattgga gttgaggaag ctattgatta cctaaagtct
     5161 atcaatgctc cgtttgggaa aaattttgat ggtagaggta tggtcatttc aaatatcgat
     5221 actggaacag attatagaca taaggctatg agaatcgatg atgatgccaa agcctcaatg
     5281 agatttaaaa aagaagactt aaaaggtact gataaaaatt attggttgag tgataaaatc
     5341 cctcatgcgt tcaattatta taatggtggc aaaatcactg tagaaaaata tgatgatgga
     5401 agggattatt ttgacccaca tgggatgcat attgcaggga ttcttgctgg aaatgatact
     5461 gaacaagata tcaaaaactt taacggcata gatggaattg cacctaatgc acaaattttc
     5521 tcttacaaaa tgtattctga cgcaggatct gggtttgcgg gtgatgaaac aatgtttcat
     5581 gctattgaag attctatcaa acacaacgtt gatgttgttt cggtatcatc tggttttaca
     5641 ggaacaggtc ttgtaggtga gaaatattgg caagctatta gggcattaag aaaagcaggc
     5701 attccaatgg ttgtcgctac gggtaactat gcgacttctg cttcaagttc ttcatgggat
     5761 ttagtagcaa ataatcatct gaaaatgacc gacactggaa atgtaacacg aactgcagca
     5821 catgaggatg cgatagcggt cgcttctgct aaaaatcaaa cagttgagtt tgataaagtt
     5881 aacataggtg gagaaagttt taaatacaga aatatagggg cctttttcga taagaataaa
     5941 atcacaacaa atgaagatgg aacaaaagct cctagtaaat taaaatttgt atatataggc
     6001 aaggggcaag accaagattt gataggtttg gatcttaggg gcaaaattgc agtaatggat
     6061 agaatttata caaaggattt aaaaaatgct tttaaaaaag ctatggataa gggtgcacgc
     6121 gccattatgg ttgtaaatac tgtaaattac tacaatagag ataattggac agagcttcca
     6181 gctatgggat atgaagcgga tgaaggtact aaaagtcaag tattttcaat ttcaggagat
     6241 gatggtgtaa agctatggaa catgattaat cctgataaaa aaactgaagt caaaagaaat
     6301 aataaagaag attttaaaga taaattggag caatactatc caattgatat ggaaagtttt
     6361 aattccaaca aaccgaatgt aggtgacgaa aaagagattg actttaagtt tgcacctgac
     6421 acagacaaag aactctataa agaagatatc atcgttccag caggatccac atcttggggg
     6481 ccaagaatag atttactttt aaaacccgat gtttcagcac ctggtaaaaa tattaaatct
     6541 acgcttaatg ttattaatgg caaatcaact tatggctata tgtcaggaac tagtatggcg
     6601 actccaatcg tggcagcttc tactgttttg attagaccga aattaaagga aatgcttgaa
     6661 agacctgtat tgaaaaatct taagggagat gacaaaatag atcttacaag tcttacaaaa
     6721 attgccctac aaaatactgc tcgacctatg atggatgcaa cttcttggaa agaaaaaagt
     6781 caatactttg catcacctag acaacaggga gcaggcctaa ttaatgtggc caatgctttg
     6841 agaaatgaag ttgtagcaac tttcaaaaac actgattcta aaggtttggt aaactcatat
     6901 ggttccattt ctcttaaaga aataaaaggt gataaaaaat actttacaat caagcttcac
     6961 aatacatcaa acagaccttt gacttttaaa gtttcagcat cagcgataac tacagattct
     7021 ctaactgaca gattaaaact tgatgaaaca tataaagatg aaaaatctcc agatggtaag
     7081 caaattgttc cagaaattca cccagaaaaa gtcaaaggag caaatatcac atttgagcat
     7141 gatactttca ctataggcgc aaattctagc tttgatttga atgcggttat aaatgttgga
     7201 gaggccaaaa acaaaaataa atttgtagaa tcatttattc attttgagtc agtggaagaa
     7261 atggaagctc taaactccaa cgggaagaaa ataaacttcc aaccttcttt gtccatgcct
     7321 ctaatgggat ttgctgggaa ttggaaccac gaaccaatcc ttgataaatg ggcttgggaa
     7381 gaagggtcaa gatcaaaaac actgggaggt tatgatgatg atggtaaacc gaaaattcca
     7441 ggaaccttaa ataagggaat tggtggagaa catggtatag ataaatttaa tccagcagga
     7501 gttatacaaa atagaaaaga taaaaataca acatccctgg atcaaaatcc agaattattt
     7561 gctttcaata accaagggat caacgctcca tcatcaagtg gttctaagat tgctaacatt
     7621 tatcctttag attcaaatgg aaatcctcaa gatgctcaac ttgaaagagg attaacacct
     7681 tctccacttg tattaagaag tgcagaagaa ggattgattt caatagtaaa tacaaataaa
     7741 gagggagaaa atcaaagaga cttaaaagtc atttcgagag aacactttat tagaggaatt
     7801 ttaaattcta aaagcaatga tgcaaaggga atcaaatcat ctaaactaaa agtttggggt
     7861 gacttgaagt gggatggact catctataat cctagaggta gagaagaaaa tgcaccagaa
     7921 agtaaggata atcaagatcc tgctactaag ataagaggtc aatttgaacc gattgcagaa
     7981 ggtcaatatt tctataaatt taaatataga ttaactaaag attacccatg gcaggtttcc
     8041 tatattcctg taaaaattga taacaccgcc cctaagattg tttcggttga tttttcaaat
     8101 cctgaaaaaa ttaagttgat tacaaaggat acttatcata aggtaaaaga tcagtataag
     8161 aatgaaacgc tatttgcgag agatcaaaaa gaacatcctg aaaaatttga cgagattgcg
     8221 aacgaagttt ggtatgctgg cgccgctctt gttaatgaag atggagaggt tgaaaaaaat
     8281 cttgaagtaa cttacgcagg tgagggtcaa ggaagaaata gaaaacttga caaagacgga
     8341 aataccattt atgaaattaa aggtgcggga gatttaaggg gaaaaatcat tgaagtcatt
     8401 gcattagatg gttctagcaa tttcacaaag attcatagaa ttaaatttgc taatcaggct
     8461 gatgaaaagg ggatgatttc ctattatcta gtagatcctg atcaagattc atctaaatat
     8521 caaaagcttg gcgagattgc agaatctaaa tttaaaaatt taggaaatgg aaaagagggt
     8581 agtctaaaaa aagatacaac tggggtagaa catcatcatc aagaaaatga agagtctatt
     8641 aaagaaaaat ctagttttac tattgataga aatatttcaa caattagaga ctttgaaaat
     8701 aaagacttaa agaaactcat taaaaagaaa tttagagaag ttgatgattt tacaagtgaa
     8761 actggtaaga gaatagagga atacgattat aaatacgatg ataagggaaa tattattgct
     8821 tatgacgatg gtagtgcctt acaatatgaa actgaaaaac ttgacgaaat aaaatcaaaa
     8881 atttatggcg ttctaagccc atctaaagat ggacactttg aaattcttgg aaagataagc
     8941 aatgtttcta aaaatgccaa ggtatattat ggaaataact ataaatttat agaaatcaaa
     9001 gcgactaagt atgactcaca ttcaaaaacg atgacatttg atttatacgc taatattaat
     9061 gatattgtgg atggattagc ttttgctgga gatatgcggt tttttgttaa agatgatgat
     9121 cgaataaaag ctgaaactaa aattagaatg cctgaaaaaa ataaggaaac taaagcagaa
     9181 tatccctatg tatcaagtta tgggaatgta atcgaattag gagaaggaga tctttcaaag
     9241 aacaaaccag acaatttaac taaaatggaa tctggtaaaa tctattctga ttcagaaaaa
     9301 caacaatatc tgttaaagga taacatcatt ctaagaaaag gctatgcact aaaagtgact
     9361 acctataatc ctggaaaaac ggatatgtta gaagggaatg gagtctatag caaggaagat
     9421 atagcaaaaa tacaaaaggc caatcctaat ctaagagttc tttcagaaac aacaatttat
     9481 gctgatagta gaaatgttga agatggaaga agtacccaag ctgtattaat gtcggctttg
     9541 gacggcttta acattataag gtatcaagtg tttacattta aaatgaacga taaaggggaa
     9601 gctatcgata aagacggaaa tcttgtgaca gattcttcta aacttgtatt atttggtaag
     9661 gatgataaag aatacactgg agaggataag tccaatgtag aagctataaa agaagatggc
     9721 tccatgttat ttattgatac caaaccagta aacctttcaa tggataagaa ctactttaat
     9781 ccatctaaat ctaataaaat ttatgtacga aatccagaat tttatttaag aggtaagatt
     9841 tctgataagg gtggttttaa ctgggaattg agagttaatg aatcggttgt agataattat
     9901 ttaatctacg gagatttaca cattgataac actagagatt ttaatattaa gctgaatgtt
     9961 aaagacggtg acatcatgga ctggggaatg aaagactata aagcaaacgg atttccagat
    10021 aaggtaacag atatggatgg aaatgtttat cttcaaactg gctatagcga tttgaatgct
    10081 aaagcagttg gagtccacta tcagttttta tatgataatg ttaaacccga agtaaacatt
    10141 gatcctaagg gaaatactag tgtcgaatat gctgatggaa aatctgtagt ctttaacatc
    10201 aatgataaaa gaaataatgg attcgatggt gagattcaag aacaacatat ttatgtaaat
    10261 ggaaaagaat atacatcatt tgatgatatt aaacaaataa cagacaagac actaaacatt
    10321 aagattgttg taaaagattt tgcaagaaat acaaccgtaa aagaattcat tttaaataaa
    10381 gatacgggag aggtaagtga attaaaacct catagggtaa ctgtgaccat tcaaaatgga
    10441 aaagaaatga gttcaacgat agtgtcggaa gaagatttta ttttacctgt ctataagggt
    10501 gaattagaaa aaggatacca atttgatggt tgggaaattt ctggtttcga aggtaaaaaa
    10561 gacgctggct atgttattaa tctatcaaaa gataccttta taaaacctgt attcaagaaa
    10621 atagaggaga aaaaggagga agagaataaa cctacttttg atgtatcgaa aaagaaagat
    10681 aacccacaag taaaccatag tcaattaaat gaaagtcaca gaaaagagga tttacaaaga
    10741 gaagatcatt cacaaaaatc tgattcaact aaggatgtta cagctacagt tcttgataaa
    10801 aacaatatca gtagtaaatc aactactaac aatcctaata agttgccaaa aactggaaca
    10861 gcaagcggag cccagacact attagctgcc ggaataatgt ttatagtagg aatttttctt
    10921 ggattgaaga aaaaaaatca agattaagat aaaagctata gaaaaaaatg gtttatgtac
    10981 tgagattaga tagtgaggtg atgacatagt tttgtgaaaa cagccattta taactcaatt
    11041 atttagttta cttcactatt gatactattt ggagttatta atggacttag tttagataac
    11101 taatgaattg attgaaaggg ttagtattga caatattggt catattgatt agaaaataga
    11161 gtctatcaaa atttaaaggc taatagaggt gatgagacaa tttcaaggaa ttaagtagcg
    11221 tttggttgct taattccttt ttatttggaa ggaagttttt cgtaaccgcc caataacgaa
    11281 gtctattgga cggttacgat atgatcactg acttcgtcag tcttatctac aacctcaaaa
    11341 ctgtgttttg agcaacctgc ggctagcttc ctagtttact ctttgattt
//
LOCUS       DAVHSH010000056        11235 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000056 DAVHSH010000000
VERSION     DAVHSH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11235
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.057"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(48..1937)
                     /locus_tag="VVR08_001725"
     CDS             complement(48..1937)
                     /locus_tag="VVR08_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU6075590.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSYLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2075..3640
                     /locus_tag="VVR08_001726"
     CDS             2075..3640
                     /locus_tag="VVR08_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6075591.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3640..4404
                     /locus_tag="VVR08_001727"
     CDS             3640..4404
                     /locus_tag="VVR08_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6075592.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4603..4818)
                     /locus_tag="VVR08_001728"
     CDS             complement(4603..4818)
                     /locus_tag="VVR08_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075593.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="VVR08_001729"
     CDS             complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="VVR08_001729"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU6075594.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6989..7345)
                     /locus_tag="VVR08_001730"
     CDS             complement(6989..7345)
                     /locus_tag="VVR08_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6075595.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7583..7819)
                     /locus_tag="VVR08_001731"
     CDS             complement(7583..7819)
                     /locus_tag="VVR08_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075596.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="VVR08_001732"
     CDS             complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="VVR08_001732"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6075597.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPSLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="VVR08_001733"
     CDS             complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="VVR08_001733"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU6075598.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9483..11183)
                     /locus_tag="VVR08_001734"
     CDS             complement(9483..11183)
                     /locus_tag="VVR08_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU6075599.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT         3391 a         2557 c         1945 g         3342 t
ORIGIN      
        1 ttctatcttc cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg
       61 atactgccgc cacctccgcc tccagagaag ccaccaccag aacttccact tccagaagat
      121 acagagtagg tgcttgctgt atttgcgaca ctagcataat ggctcatttg tgctgttgaa
      181 tgataaaaca tactgtgcca gccataagct acatagagat tgatatctgg attttccact
      241 tgaatctgat gaaccttcat caaataacta accttgtccg catagccaaa taaggtcgca
      301 tagaccaaga ggcgattcca gaccacaata ctttccagtt cagcctgatc caatcgtgca
      361 atctcacgca acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca
      421 tttagaacac catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact
      481 aaccctagaa aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg
      541 tacaagaaca aaccaaatcc gataaatagg ggcaggatag tcaaggcacc catacccact
      601 tgcaaggcct tttccccacc agttaaagga cgataataat ctgggagccc ccagaaggaa
      661 actcgttttc tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt
      721 tgaagccctc ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta
      781 tcagatacct tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa
      841 gctagattta ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa
      901 ccaactgcat ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag
      961 gtagcttgaa taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact
     1021 tcctccaagg aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggt
     1081 ggttcataga gacgatgatt tttggcatat ttgactgaag gagtggtctt tcttctataa
     1141 ataaaataga agcagacact caataacaag gagatagaaa ggatcgaagg gaggacccaa
     1201 gtaacaagtt gtttactctg atctttttct ctaacaatcg agtcttctat cttattaaac
     1261 tcttctaaac gattcccttt caatccctga tccctagcgc tagcaaaatc ggtccgaggc
     1321 caataggcat gcaactcaac tccacgctta gccggaagat tgtctaaacg gatagtataa
     1381 tcaaggttac tcttttcaat cgttccctct ctaaaaagtt tccctgtatg gaaaaagagt
     1441 ttttcagccc ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta
     1501 tctgtcagag gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt
     1561 aagttccaga cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc
     1621 acagtataac catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg
     1681 tttttcgcgg cctgaacctt tggatgaggg tcaatgtcaa acccgctagg catcttacca
     1741 gcacgtccaa gtcccacgat ttgtccctta aagtcctcct caaactggta aactatcttc
     1801 tgtctaaact ctgccgtatt atctgcatga atatacaaat ccccttgata agagtttatc
     1861 ttgaaatcaa tggcaaaaac agagagtgga agaaggcaaa acaagcctaa caccagtaag
     1921 aaaaaagttt ttttcatcaa ctaagccccc tttttatctt tcttatcatt atagcatttt
     1981 ttcgtaagta aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac
     2041 agttattttt taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt
     2101 cacaagtctc ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg
     2161 catcggtatg gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg
     2221 agctgtcaaa atcgatggga ccaatcagta tgccaacgga tacgatgttc aaatcgccaa
     2281 gaaaatcgct aaggacttag gtaaagaacc tttggttgtt aaaaccaagt gggaaggtct
     2341 agtccctgcc cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc
     2401 agaacgcaaa caagaaattg ccttttcgag cagttactac actagcgaac cagttctact
     2461 ggtcaaaaaa gattctgcct atgcaagtgc taaatctttg gatgacttta atggtgcgaa
     2521 aatcacttct caacaagggg tctaccttta tgacttgatt gcacaaatca caggtgctaa
     2581 aaaagaaaca gccatgggag acttcgctca aatgcgccaa gctcttgagg ctggtgtcat
     2641 cgacgcctat gtttctgaac gcccagaagc tctgactgct gaagctgcga actctaagtt
     2701 caagatgatt caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat
     2761 cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc
     2821 aaaagatgac caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac
     2881 aacaactgaa gagactagca gtagtttctt tagccaagtc gctaaaattc tttctgaaaa
     2941 ctggcaacaa ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat
     3001 cataggtctc attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa
     3061 caaagccatt tatggccttc aaaaactagt cggctgggtt ctcaatgtct acattgaaat
     3121 tttccgtggt acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc
     3181 tttcggtatc aaccttgacc gtacactagc tgctatcttc atcgtttcaa tcaataccgg
     3241 tgcctacatg actgaaattg tccgtggtgg tatcctggca gttgacaagg gacaatttga
     3301 agctgcgact gctcttggta tgactcataa ccaaaccatg tgtaagattg tcctacctca
     3361 ggttgtccgc aatatcctac cagcaactgg taatgaattt gtcatcaata tcaaagatac
     3421 atctgtattg aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac
     3481 acaaacctat caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac
     3541 cttcaccgta acacgtatcc tacgctttat cgagcgcaga atggacatgg atacctacac
     3601 tacaggtgct aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa
     3661 attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttctctcact
     3721 gtccacaagg gagaagttat ttctatcatc ggaagctctg gaagtgggaa atcaaccttc
     3781 ctacgctcca ttaacctact tgaaacgcca actgatggac aaatccttta tcatggacaa
     3841 aacgtcctcg aaaaaggcta tgacctcacg caataccgtg aaaagttagg gatggttttc
     3901 caatccttta acctctttga aaatctcaac gttcttgaaa acacaatcgt cgctcagaca
     3961 actgtcctta aacgcgaacg cacagaagct gaagaaattg ccaaagaaaa cctggaaaag
     4021 gtcggcatgg gagaacgcta ctggcaagcg agacccaaac aactctcagg tggtcaaaaa
     4081 caacgtgtgg ccatcgctcg tgccctttca atgaatcctg acgccattct ctttgatgaa
     4141 ccaacatcag ctctcgatcc agaaatggtt ggagaggtcc tcaaaatcat gcaagatctg
     4201 gctcaggaag gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatgtc
     4261 tctcaccgtg ttatctttat ggataagggt gtgattgctg aagaaggtaa accagaagac
     4321 ctcttcacta atcctaaaga agaccgtaca aaagaatttc ttcaacgtta tctcatactc
     4381 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actgttttga
     4441 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatcaa ataaaaagaa
     4501 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     4561 tctctactac ttgaaggtca agaatccacc gttatccaaa gattaatctt caaatttttc
     4621 atgatttttt tcatagaaat caattaagcc tagggctgtt tcaaatgaaa tattttttac
     4681 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     4741 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     4801 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     4861 gtttttacta cttttgtcaa taaaaaaaac atatattcaa cgaaaataat tagttcagaa
     4921 ttttcttact tcctttttaa atccgataat atataggttt tgctagcctc tacaccataa
     4981 atatttgcta ataaaaatac tgtattatta ccctcttaag gtgcaaaatt attcaagttc
     5041 ttaaaaaatg cttctctatt tccgtaagat agcttatttc ttcgatttaa gaactgaaga
     5101 tgatagttct aacctttaga aatccaagcc ttctctagct caaaaactcc tatctttctt
     5161 cctcaataaa tcatctgaga gataggtatt ccttatatcc ttcaaattca tcactccttt
     5221 ggatattgag gtgctagcct agaagcagac acccgattat ctaaaccatc cttaatagag
     5281 atgacaagac agataagctc agttaattac ttatatatct ttttaatatg gtatatttgt
     5341 caacaaaaag aaatcaaatc ataccttata ctcaatgaaa atcaaagagc aaactaggaa
     5401 gctagccgca aattgctcaa aacactgttt tgaggtttca gatagagcta acgtggtttg
     5461 aagagatttt cgaagagtat taaagacagt atgactatgc ttgtcaatag ataggaaatc
     5521 aaaatgaagg atggaaatct gagccaaaca tcataagtgc tataatgaac agaagtaaga
     5581 attgcacgat aagttttcta aaaccatagg aatcgtcccc tttcttcatc ttcattatag
     5641 cacatataca tcagttgtac aaataatatg atattttttt attagtcctc agacaagcat
     5701 attataaagc gtttcattac catttaagtt aatataagct ggatcaaaac cttccattct
     5761 acggatcaaa cctgcataat catgcttatc tgccaaagcg atcccaatca atactgggcc
     5821 tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg atatcatcat ttggccccag
     5881 gatatcattt acaaactcac gcaaagctcc tggacgctgt gggaaattga ccacaaagta
     5941 atgtttgata ccatcataaa tcaaggcacg ctcttccatt tctggcatac ggttgatatc
     6001 attatttcct ccagaaatga tacaacaaat ggttttcccc ttaatatatt cagctaaaac
     6061 ctctaaagag gcgatactag ccgctccagc aggttctgcg actatccctt gcttagagta
     6121 aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca cctaccaaag tttgaatatg
     6181 ttgacgagtt gcttcatagg tcaactgacc taccttttgc acagcaatcc catccgcaaa
     6241 tttatcaatt tccttgagtt tgactggacc tccagcctca aaggcagctt tcatggaacg
     6301 cgctccattc gcctctactc cgataacctc aatctctgga cttgtttcct tgatataggt
     6361 agaaaccccg gcaatgagac cgccaccacc aacaggaacc aagacagcat caaaatcaat
     6421 cgattctttt cgagcttctt ctaaaatctc ataagcaact gttccttgac ctgcttgaac
     6481 atgagcatca tcaaaaggat caataaaggt acgattttca gagactgtaa attcttgagc
     6541 tgctttggct gaggcatcaa aggtatctcc aactagttta atagttacaa aatccccacc
     6601 aaaaaagcga acctgaccaa tcttttgttg tggcgtagta ataggcataa agatagtagc
     6661 aggaattttc atttcattac aagtataggc tactccctgc gcatgatttc ccgcagaagc
     6721 gcagactacc ccacgttcac gttcttcctt gctgagctgg gaaatggcat aataggcacc
     6781 acgaatttta aaggagcgaa cacgctgggc attttctttt ttcaaataaa tcttagcacc
     6841 atacttctcc gataaataat gatcgtaatc cagtggagta ttcacaacca caccgttcaa
     6901 gaccttgtga gccttgatta tatcttttga acttaacata taaaacctct ttttctataa
     6961 aaaacagtca ctaatgactg ttttttagtt attcatctcc gaaaacttca gtaacacttt
     7021 catggtattt atgagccata cgaatcgaaa actctttagg aagttcataa cgatttgtgg
     7081 aaatccaatc atataaccat tctaccaaac tttcttcact atcattacga tggaagataa
     7141 aatagtttaa aatttcttta tattctacat cattcaaatc caacgtgtct acaaattgac
     7201 tacgaggaac aaaattagaa tctaattttc ttagttgatc tgtcaattct cccaattgta
     7261 aatccaactg aaaaaatagt ttttgcagtt gcctatcagt ttcatcacat cctgtcttga
     7321 tagaaaacaa attggtaata ttcatatgat ttcaacccct aaataagtac atctaatatc
     7381 ccacgaatag ctgaagctaa agttttcgca gtccagtcat ttaaacccga ttctttcaat
     7441 ccagatgcaa taatttgctc tatttgatat aaaccgccat ctatcgtctc atttattctg
     7501 cgaagaggac cttcaatata ggataaagct tctccgaatc taacagctga tttaggtcct
     7561 aatgatttac caactatatt tgttaatgtt ttttatttct caaaatccat ttcgctatat
     7621 aacgagcaga tttagtcgca ccagctctct caaacggaga atgaatttca agaccttctt
     7681 ctctagctat ttgtgccaat ttgaagaatt gttcaaaggt catatgcaac ctaccatctt
     7741 caaaattagc atcatcataa atgttaatta cagcattttc atcatacgac caatctgctt
     7801 tattttggtc tgctagcact attaccgacg gtgtaattac attatacaac tagaaccaat
     7861 aataacgatg caatttttct cataatcttt ttcataaaat catctccagc gctatatatt
     7921 tctaattagt tatagatttt gaatgcatca tcgtcgtttt taccaacaaa tggcattgct
     7981 ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag ctgcttgttc acggtaagca
     8041 gtcaattttg gacgtccagc tttatagtca tttacaaagt catttgcaaa tttaccattt
     8101 tggatgtctg ccaagacagc cttcatattt tctttaactt gttcagtgat tacacgtgga
     8161 cctgatacat agtcaccgta ttcagcagtg tttgaaatag attgacgcat tttcttgaat
     8221 ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt gaagaacttc aaagtaagcc
     8281 aattctggag cgtaacctgc ttctgtcaag acttcgaaac ctgcttcgat aagggcagtc
     8341 aaaccaccac aaagtacagc ttgttcacca aacaaatctt cttcagtttc ttctttgtaa
     8401 gttgtttcaa gaagacctac acgagccgct ccaacacctt tacaccagtc catagcaatg
     8461 tttttagcat ttcctgttgc atcttggtat actgcataaa gagctggaac accaaatcct
     8521 tcttcgtaag tacgacgtac caagtgtcct ggtcctttag gagcacacat gaagacatct
     8581 acatccgcag gaactttgat aaattcaaag tggatgttga aaccatgggc aaatccaact
     8641 gcgtttccag cttccaagct tggagcgatt tctgcttcgt acaattcttg ttgaatttcg
     8701 tctggcgcca agatcatgat aacatcagcc aacttagtag cttctgctac tgtgtaagta
     8761 tcaaatccat cttcttttgc tttatcaaaa gatttacctg gacgtacacc gataataacg
     8821 tcacgacctg aatcacgcaa gttttgagca tgcgcatgcc cttgtgaacc ataaccgata
     8881 acggcgattt ttttaccgtc aagtgctgct actttaacat ctttttcata ttccatttga
     8941 actgtcatag cttttctctc ttttctatta tttattgcct tttaggctgg tttaataaat
     9001 ttaagttgga tttttaatcg cgggtaaatc cagttgcacc cgttcgagca atattgcgaa
     9061 taccgtatgg gcgaatgact cgcaataggg cttcgctctt ttctgcattt cccgtcatct
     9121 gaatggtaat cgagctcggc gctacgtcta ccactgttgc acggaaaggt tgaataatcg
     9181 ctaaaatctc agctctcttc tcagctggcg ctgacatctt aaccaaaatc acctcgcgct
     9241 ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac atcaatctga cgattgagct
     9301 gtttgatgat ttgctccact tcatcatgag aagcaacatc aataataata gtgatacgcg
     9361 atacattcgg atcttctgtt gctccaacag agatgctttc aatattaacc tgacgacgag
     9421 ataggacacc tgtaaagcga ttgaggactc ctgaacgatt ttgtagtttt gctgttaaca
     9481 ttctacgcat ggaactgcac ccccaacatc tcatgattac tcttaccagc cggtaccatt
     9541 ggtaacacct gttccttacg agaaatatct acctcaatta gcataggaac atcctcagtg
     9601 atgacttcaa ggtcttgagc caaggtctca ggattgtcaa acttatagtt tttaatacca
     9661 taagcctgcg ccatcaattg gaaatcagga agggtatcaa agaccgactc tgatgttctg
     9721 ccttcataga aggattcctg ccactggcga accattccga gtgaatgatt gttcagcata
     9781 accaccttga ttggcacctt gtaaatattc aaaatagcca actcctggtt ggtcatttgg
     9841 aaaccaccat ccccaacaaa caagactact tccttatctg ggttagcaat tttagcaccg
     9901 attgctgctg gaattccaaa gcccattgtt cccaaaccac ctgaagtcac taactgacgt
     9961 tcattttggt agggataata ctgagctgtc cacatttggt gttgaccaac gtctgttacc
    10021 acaatggcat ctccattcgt caattcacca attcgttcaa taactgcttg cggttgaacc
    10081 acacgctctt tcttgtcata agaacgaaca cgattcttgt ctttagtgac tttctcaatc
    10141 cacttttcag tattgttgtg aactgttggt tctgctagca acatttgcaa ggccttctta
    10201 gcatctccaa ctacaggaat gtctgcactg ataatcttgc caatctcagc tgggtcaata
    10261 tcaatgtggg caaccttagc attcttagcg aaagtcttag gattccccgt caaacggtca
    10321 tcgaaacgag aaccaatact aatcataaag tccgcttccg tcatggcaat atttgctgcg
    10381 aatgacccgt gcatgcctcc cattccaaga aagagtgggt gactcgttgc aatcgttcct
    10441 tgtcccaaaa gactggttac cactggaatt tgatagcgtt ctgcaaattc atttagttcc
    10501 gtagcagcct cagcataact aattccacca ccagctaaca agactggctt tttagccttg
    10561 gacaattgct tcaagatttt cttgatttgc atatcattcg gctcaagagt cggctgataa
    10621 cttggtaaat tcacttctgg tgaataaatg aagtctgttt ctaaagcaga tatgtctttt
    10681 ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg cgatatggac agcttccgta
    10741 atgatacgcg gaatatcagc tgtctcacga acttggtaat tgtacttagt gattggcatg
    10801 gtaattccca cgatgtctgc ctcctgaaag gcatccttcc caatccctgc tcgcgccacc
    10861 tgacctgtaa agaccaaaag gggaacgcta tcgctcatgg catccgcaat ccctgtaatg
    10921 gcatttgttg ctcctggtcc actagtgacg acggcaacac ccaactttcc agttgatttg
    10981 gcataacctt cagcttcatg caaacaacct tgctcatggc gccctagaat gtggcgaatg
    11041 cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg caccaccagg ataaccaaag
    11101 atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta ggtccgaccc cgtcttagga
    11161 gattctaaac tgattttctc cattgttccc ctttctttcc tcttaaaaat aacttgttac
    11221 tatcatacca ttttt
//
LOCUS       DAVHSH010000057        11164 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000057 DAVHSH010000000
VERSION     DAVHSH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.058"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            19..1131
                     /locus_tag="VVR08_001735"
                     /pseudo
     CDS             19..1131
                     /locus_tag="VVR08_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1259..2281)
                     /gene="cbpF"
                     /locus_tag="VVR08_001736"
                     /pseudo
     CDS             complement(1259..2281)
                     /gene="cbpF"
                     /locus_tag="VVR08_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(2300..3121)
                     /gene="cbpG"
                     /locus_tag="VVR08_001737"
     CDS             complement(2300..3121)
                     /gene="cbpG"
                     /locus_tag="VVR08_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU6075600.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3202..3441)
                     /locus_tag="VVR08_001738"
     CDS             complement(3202..3441)
                     /locus_tag="VVR08_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075601.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3591..3857)
                     /locus_tag="VVR08_001739"
                     /pseudo
     CDS             complement(3591..3857)
                     /locus_tag="VVR08_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3948..4193)
                     /locus_tag="VVR08_001740"
                     /pseudo
     CDS             complement(3948..4193)
                     /locus_tag="VVR08_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(4118..4349)
                     /locus_tag="VVR08_001741"
                     /pseudo
     CDS             complement(4118..4349)
                     /locus_tag="VVR08_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(4350..4982)
                     /locus_tag="VVR08_001742"
     CDS             complement(4350..4982)
                     /locus_tag="VVR08_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075602.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(4996..5991)
                     /locus_tag="VVR08_001743"
     CDS             complement(4996..5991)
                     /locus_tag="VVR08_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6075603.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKDRVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5988..6686)
                     /locus_tag="VVR08_001744"
     CDS             complement(5988..6686)
                     /locus_tag="VVR08_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU6075604.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6764..7774)
                     /locus_tag="VVR08_001745"
     CDS             complement(6764..7774)
                     /locus_tag="VVR08_001745"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU6075605.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFSGRKWDFPFYINAMTGGSNKGREINQKLAQVAETCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGFQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7758..8765)
                     /locus_tag="VVR08_001746"
     CDS             complement(7758..8765)
                     /locus_tag="VVR08_001746"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU6075606.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSIDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFARQKVAAWLKEEKLATVLERDWGFSISQVRPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8752..9705)
                     /gene="mvaD"
                     /locus_tag="VVR08_001747"
     CDS             complement(8752..9705)
                     /gene="mvaD"
                     /locus_tag="VVR08_001747"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU6075607.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTARPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9687..10565)
                     /gene="mvk"
                     /locus_tag="VVR08_001748"
     CDS             complement(9687..10565)
                     /gene="mvk"
                     /locus_tag="VVR08_001748"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU6075608.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10687..11016)
                     /locus_tag="VVR08_001749"
     CDS             complement(10687..11016)
                     /locus_tag="VVR08_001749"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075609.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
BASE COUNT         3352 a         2539 c         1992 g         3281 t
ORIGIN      
        1 aattctaatc ttaggtatat gattaaattg attgatcgtt acggaataga gttcgtcaaa
       61 aaagggaaaa atcgttacta ttctcctgat ttaaaacaag aaatgattaa taaagtctta
      121 tatgaaggct ggactaaaga tagagtttct cttgaatacg gcctcccaag tcgtacgata
      181 cttcttaact ggctagcaca atacaggaaa aacgggtata ctattgttga gaaaacaaga
      241 gggagagtac ctaaaatgag acgtaagcca aaaaagagac ctgaagagag gacagaatta
      301 gaacgtcttc aagcagaaaa tgagtacctg agagcggaga aggccatcct aaaaaagtta
      361 agagaactcc gattgaagga ggaaaaagag aaagaagaaa gatagaaatt gttcaagaat
      421 taatgactga gttttcgtta gatcttcttc taaaagccat taaactagct cgttggacct
      481 actactatca cttgaaacag ctagacaaac cagataagga ccaagagctt aaagctgaaa
      541 ttcaatccat ttttatcgaa cacaagggaa attatactta tcgccgggtt catttagaac
      601 taagaaatcg tggttatctg gtaaatcata aaagagttca aggcttgatg aaagtactca
      661 atttacaagc taaaatgcga cagaaacgaa aatattcttc tcataaagga gacgttggta
      721 agaaggcaga gaatctcatt caaggccaat ttgaaggctc taaaacaatg gaaaagtgct
      781 acacagatgt gacagaattt gccattccag caagtactca aaagctttac ttatcaccag
      841 ttttagatgg ctttaacagt gaaattatcg cctataatct ttcaacttca cccaacttag
      901 aacaagtaca aacaatgttg gaacaggcat tcacagagaa gcactatggt ggagtccttc
      961 tttgggattc tgaaatcgga aatgttttat ggctatgaga aaacatttaa atcacttaat
     1021 caattggaac aagctattat agactatatt gattattaca acaacaagag aattaaggta
     1081 aaactaaaag gacttagtcc tgtgcagtac agaactaaat cctttggata aattatttgt
     1141 ctaacttttg gggggcagta cagaaaaacc ttgatactat gcgttttttg attgtgaaga
     1201 cttttatcca cctattatac aaagttaagt atccatcaca gtttacaatt agccttcatt
     1261 acttaaccca ttcaccatta tagtttaagt agtaaccacc tactgtggta ttaacagcta
     1321 aagcacctga atcataggca tagtaccagt taccattgac ttggaaccag cctgttttca
     1381 tatctccatt acttgcattt agatagtacc aagtcgaacc ttcctgatac caaccagttg
     1441 ccatagctcc tgatgaacgg agatagtacc acttgttacc aaggtattgc cagccagttc
     1501 tcatatcacc attttcagca tctagatagt accaagttga gccttcctta taccagccag
     1561 ttgccatagc tcctgacgaa tggaggtagt accatctatt acctagaaat tgccaaccag
     1621 tttgcataat gccagttgtt ggatctagat agtaccatgg agctgctttt agcttctctt
     1681 catcataggt aagaggggaa tccttaaccc aaccacgtgc tagctctcca accgccaatc
     1741 tgttgatgcg cgaatcaaag ccaccatcct tctgtaaata ataccaatga ccctcttcgt
     1801 aaatccaacc agtttttaaa gtatgataac tacgctgatc ttcaaaataa tagactcatt
     1861 tctctgctgg gctatcatat tcttccccat gatgtttgtt ggtattcgta gcagtttttg
     1921 cttctaaaac ttgcttgcca acaaattctt gtaatacacc atcttgacca aaataaaacc
     1981 aatctggtct aagagaaatc tctattcttg gagaaggacc aatcgtaacc cccttgtgtg
     2041 gagcaggtat atattgccag ccgacaacca tctctccgga taaaggatca aaataatagt
     2101 acttcccatc tatcactctc cagtaggttt cttttagatc cccctttttg tagtaggttc
     2161 taccattttc ttggacaaac tgccatcctt cagaatcatc tgcaaatact gtactggtcc
     2221 ctagcaaacc gaagaaaaat gtggctagtg cgacttgcat catttttttc aaaagcttca
     2281 ttttatatat cctccaacat taaatccact caccagatga agcgaagtta taaactttac
     2341 catcgatagt ttggctacct gtaaccattg ctccatttga attgagataa taccattttc
     2401 catttacttt ttgccaatct gtaagcatct taccggaact gtctaaataa taccaagtat
     2461 catttatctc ctgccaaccc gtttgtttat catgttgtct ataatggtac caactaccat
     2521 ttattttctt ccatccttca agagagtaac ctttaagaac cgaataaata aatggcaaat
     2581 ttcgttcatt taatttaact gcactgttaa tttgattagc tccatctcct aaagtatgca
     2641 ctcctactac acggtgacta gcatcataaa ctgtagatcc actagacccc tctaaagtat
     2701 caacttggta atccaagaac atgccatcat cacttaaaac ttgtttttta tctgtataca
     2761 tttgatgaat tttaaaatta tatgatggat agcctgtgat agtcacagtt attcctgtca
     2821 aatttttttg actagtagga agacccaaag tccctaattt tgcaccaatg ggctcttcta
     2881 gaattaataa agccaagtca tattcccttg catccttaga atttaaattt ctaaattcct
     2941 tcaaataacg aacttccttt actttgatct ttccaaatgg ttcttgactt ggactaacag
     3001 ccggaagaac ataaatatca tccgcttctt tcccatagtc atgtctgtag tagttgtgag
     3061 ccgctgtaat taacacatta tctttaataa aattcgcact tcccctccct tctacattca
     3121 ttccatcggc tactccataa tacttagata aaaccatagc tgaagtcgaa tacggatact
     3181 gtaaagtatt atcaatttta atcaaatcat cattaccgat aatacttctg attgcttttg
     3241 gtagtatgaa ccatatgttg gtgaaatctc agataatgaa gaatcattag atcctggacc
     3301 tttttctagt gtctcactta cctcatattc ttcacccgta ctagaaataa cactcaaagc
     3361 agatactgtc gataactggc tagccaataa agtactcgca ataattgaaa tacccaattt
     3421 tttataaaca gttttcttca ttattgtagc ctcctaatgt aattatagcg tactattcta
     3481 aatttcttaa tctactatag aatcaagaaa tctaccacct tctttaaata ccctccatta
     3541 tcacataaac aggtaaactt ttcaattaat gactgcgctt ttcaatcacg ctagaggtac
     3601 ttgcttgctt ctttgatact aagttcagcc attctttcct tatttttctc aataaagcat
     3661 gttacccaag tgggattcgt tttggagtag tctcgcagag tccagccaat ggctttattg
     3721 ataaaaaatt ctgtttggtt caagttatga aggagaatct tttccattaa ttgagtattg
     3781 gtcttctctt ttcttaacaa ctggtggtta atagcgacac gtctcagcca gatattatct
     3841 gataggctcc attttatact caatgaaaat caaagagcaa actaggaagc tagccgcaga
     3901 ttgctcaaaa cactgtttta aggttgcaga tagagctgac gtggtttgaa gagattttcg
     3961 aagagtatta agattatttc ttctagctca gggtgttcat acaccaaact ccctactact
     4021 cgatctagga tatctaccgt gtcccaccag gattttgtca cgactaactg ctctagctta
     4081 ggcaaatcgg tttcctttag ataagactgc attgctttca aatagttagc agccacatat
     4141 tggtattttc taggctcctt ttcccagcaa gtgtctgcaa aatcccaatc gataatcttt
     4201 gtttttttcg cttctggaaa atatttttat agagtttatt tctttcaacc tagaaaagaa
     4261 aattgatggc acatataggc ttccatgggc cttgcttttt tagagtcttt tgctgcttct
     4321 agctcctcaa gtaaatctgc taaactcatc taaaactcct catgcccgac caaatggtgc
     4381 tgaaaggcat agacagccgc ctgggtacga tcgctaactt caagtttggc aagaatgttg
     4441 gacacgtggg tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt
     4501 tcgtagccct tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga
     4561 agttccatat gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc
     4621 tcgccagcag ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc
     4681 atatagcctt tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag
     4741 gtcacaatca aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc
     4801 ccattcatct caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc
     4861 aagtcaatcc cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg
     4921 tcaaagtagc ttttcaaacc caaacggacc atttcatggt catctactag taaaattttc
     4981 atctttactc ctttatcatt ccttatctaa caggggaata cggatatcaa ctgccagccc
     5041 ttgcttggga gctgttaata actgaaccgt ccctgccata tcttcaaccc gatccttgat
     5101 atttcgcagt ccataactca agtcgtctaa gctccctaac tggaaaccaa tcccattgtc
     5161 caccaccttc agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc
     5221 ctgggcatgg cggagcgtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc
     5281 gattttctta ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc
     5341 ctcaagctct tttaagagaa tttgaatccc ttctatcaag ctcttctgct ccagttcaac
     5401 tggtcgcaaa tgcaagagca aaacccgcaa atccttctgg gctgtttcta aaatagctgt
     5461 gacactctgc aactgggtct gcatcttttc tctatccaat ttcaaagcct gctgactgat
     5521 acccgataaa atcatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg
     5581 agcaattcgc ttccgttcct tctcgatgat ttcctcttcc tgagcaaggc tatgattttc
     5641 agctttttga agagcctctg tcaaaaggtt aagtttacct gataaggact tgaaactggc
     5701 atccaaatct ggatctacaa cctgaactac ttcttgccct gccaataaac gcttgagatt
     5761 agcctgcatt tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca
     5821 ggtcatggac atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc
     5881 gtgcaaaaag atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa
     5941 gacaaatagg aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc
     6001 acctccacat caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga
     6061 tagtcttttg tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa
     6121 aaagtcaaat ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg
     6181 atgattttgg tcgttcctac catctttctg aggataatga cattgtcatg attggttaag
     6241 atgaccctct ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatca
     6301 aattggcaag tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc
     6361 ttcttaaccg tcacgacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc
     6421 atcgggtaaa gaagaaagag gctatagata accgcaacaa aaatagctag aatcacaaaa
     6481 ggattgagca taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattt
     6541 ccctctttac cagtgtagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa
     6601 cgcgaaaaat gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata
     6661 aataaaaaga ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt
     6721 caaaaaagtc acctcagtct gaggatggaa aaaaaggcgc tggttacgcc tttttcatct
     6781 gatcatttgc ttcttttaat tttccataaa gaagatagtc tactttttgt agatctgcta
     6841 tggtggcaca gttaagggaa cacataatca agcgtagatc tgctttccag ccttggacaa
     6901 tgccaatcac ttcttcaact gtgtaggttt caaccaattc cagaacggtt cgtgacaatc
     6961 ccacagcctt agcaccaaaa accaagcact taatcatatc cagcggattc cgaacccctc
     7021 cactaaccaa gagttcgacc ttatctttcc attcttgggc attgagaagg gcctgcatgg
     7081 tagactgacc ccattgattg aggtaatcac gctggccact acgacggttt tcgatatagg
     7141 caaagctggt gccaccacga cccgataggt ccactgtacg aacaccgaat tcataggctc
     7201 tttcgattgt cttggcatcc attccaaagc ccacttcctt gaggacaata ggaacgggaa
     7261 tttgcttgct ataatctgct agatgcgatt gccagcttct aaacttcctt tctccctcgg
     7321 gcatgagtaa ttcctgcatg acattgacat gcacttgcaa tagaacagga ttcatctctt
     7381 ctacagtctg aaatcctaac tcgacaggct tgtccaatcc aatattggtt ccaaggagga
     7441 gattgggatg actagacttg acagaaaaag aatcatccgt tggatttttg agggctgcgc
     7501 tataagaacc cgttacaaat aaaataccac aggtttccgc cacctgagcc agcttttgat
     7561 tgatttctct tcccttatta cttccaccag tcatggcatt gatataaaaa ggaaagtccc
     7621 actttcgacc agaaaactct gtcgaaagat cgatttcatc cagattgtaa agaggcaagg
     7681 aagaatgaat cagctccacc tcatcaaagc tattatagga acttttctgc tcaagggcat
     7741 agaggatatg ctcgtcctta cgatttgtcg tcatgtccta tcctttcttg atataagagc
     7801 tcaatcccca gatcggccca acgatttttt aaggttttgg ttgattgcgc atcaaaactc
     7861 agggcgatgc cacagtcacc accaccagca ccactactct tggcaacggc ctgcaaatct
     7921 tgactggctt ctttcaactg tctaagcaaa ggcgtgtaaa tatctgtact caagccttct
     7981 aaaagcttgc tggctacttc tacttgctcg ataatctttt ctgatttccc ctgttccaag
     8041 gcttcgacca aagaaaccac cgtttctttt gaggaagtta aaaaattttg attgatattt
     8101 tgcttgattt gctggaccat gtgactcgat acagccactt ccttggtcca tcccactaag
     8161 aaatcacatt ctaaagttgg tctcacttgt gaaattgaaa agccccaatc acgctctaaa
     8221 acagtcgcca atttttcttc tttcaaccaa gcagccacct tctggcgagc aaatgactgg
     8281 tagagaacca aatcctctgc cacaatacag gcaaggtcgc ccatggaacc attgtctcct
     8341 cgcttaagca agacagcgct agtcagcttg aacaagagat tctgatcaat cgaaagatta
     8401 tagagagcca gtaaagcctt gacaaccaag acaacgacgc tgccactaga acctagacca
     8461 aactttttcc cttctcgttc cattttgcca cagatttcta gggaaaaagg tcttaaattc
     8521 tgaccgcgaa cagcgaggaa gtctcccatc aaagcaatcg tttcttgaat caagctatag
     8581 tcaggattgg gccttaagtc cactgcgaaa tcaaacatat ctgaatagat acggtagctg
     8641 tcagaaaaag caatctcagc cctcatatag atgggaatat cctttatcaa agctaactgc
     8701 cctggctcta aaatagcata ttcacctgcc caatagagtt ttccgcaagt tttaacagca
     8761 atcatcttga ctcaaatcct ttgtttttga cacaatcaag cgataacgct gaccgaaaat
     8821 ttctgacaaa tgctccaagt ctttctcctg acagaagacc ttaacattgg gaccagcatc
     8881 catggtaaag tagcaggcct ctcctttctc acgaagctgg cgaacaaagt ccatagcctc
     8941 ataagaggca tccgtcagat aagaaaaggc tggcctagca gtctttgtcg tagcatgcat
     9001 agccagggca tttttctccg ttaattctcc aatcttggca aaatcatttt ccttgagata
     9061 aatcagcata tcctgatagt ccttctcaga ctgacgaacc cagtcgtcaa aagtcgtcga
     9121 ggtttccaca caaagtttca tcccgtcacg gctagagatt ggttttttct tgtcctctag
     9181 caccaacata atcatagcta gtttcaagtc tgtctctaca gggtaaattt ctccactatc
     9241 cttatcccag gctcctagtg gtccataaaa actccgagaa gaagaacctg aggcaaactt
     9301 ggcttcctgc gctaactgac ttctatccaa tccaagcttg aaataagcat tacaagcctt
     9361 gaccagggcg gacaaaccac tagaacttga ggacaggccc gctgccgtag gcatattgtt
     9421 ttgagtatcg atacggacaa agccctcacc agctggacga taacggtcaa taatcttact
     9481 catcttggca tgctcgacct cattttgtag ctgaccattg atgtaaaatt cgtcagctgt
     9541 tacattggct ggtaaaggcg acaaggtcgt ctctgtatac atattttcca aagttagaga
     9601 aatactgcta gtagcaggca ccatctcttt ttcttttttc tttccccaat atttgataat
     9661 agcaatattt gcgtaggaac gtactgtcac aggctctcta tccatgtctg aacagctcct
     9721 ttctcttcta atctttctgc tagttcttgt gcgtgtgtca aattggttac caaggctatg
     9781 atacaacctc ctagcccacc accgctcatc ttggcaccca gagcaccatg actaagagct
     9841 gtttcaacca aagagtctgc ctcaaggcta ctgacaccaa tttcttttaa atgtaaatgt
     9901 gcttgactga ggatttgtcc cagcccttca gcatcttttt gtgaaatcgc aacttctgcc
     9961 tgctgggtta attctcccaa ggcatgcaaa aacggtaggg catccttgcc cttattttga
    10021 accacttgga tggcttcacg agtatgacca taaacacccg tatcggcaat caccaaatag
    10081 gcggataaat ccatctcaag ttctgtaaat cctacgttct tgataaagcg aataggttgg
    10141 tcactgagac aggtcttagc atccaaacca ctaggattca tatgggcaat catttcagct
    10201 cgattgacca agatttctag tacatcatga ggcagatcag cctgatagta gtcaaatacc
    10261 gcacgaatgg ccgctatgct gatagccgct gacgaaccca tcccccgttt ctcagggata
    10321 gccgagtcaa tctcacaacg aatgcaggct tctgtgatat tcaaatactc cagtgaggca
    10381 taaaccgcca tggacaaggt atcctcctca taaaggcgcc aaggactctc tgcaggaact
    10441 accttacagg tcacctccac ctccaaaaga ggcagggaaa tggcaggata accgtaaacg
    10501 accgcatgtt cccctatcaa aattatctta ctatgtgcct gaccgacacc aacttttttt
    10561 gtcatttttt ccttttacta gacgaaaaaa cgtcttattt ttcatacaag tattaattct
    10621 ttcctatcta ttttattata ttttcacaaa aaaagcgatt gtttccattc acaatcgctt
    10681 ctttcattat tgaacccatt cgccattata gttgacagaa tagccatcta cagtcgtatt
    10741 cactgccaag gcacctgagc tataagcgta gtaccatctg ccattgacct ggaaccaacc
    10801 tgtcgtcata gaacgacgaa agaaactcca taccgttaag taaagaggaa agtcgtgagg
    10861 gagcatgcgc cattgacaac ctgttttagt gacgtacaaa gtctcattaa caagtactcg
    10921 tttcggccat ttataggtgc ggtgtttgga gaaatagggt tcaatcttag cccattcttg
    10981 atcatttaaa tcagtatcat atgctttgcg tgtcataact ctagtttaac atttttttgt
    11041 gaatagaggt tctaaataat cgaccacgaa aatttcttaa gtggaaaacg ccttatgaag
    11101 tatgctacgg gaaagttatg cacttaattt gacaattcaa gatgtaaaaa tatatactat
    11161 agta
//
LOCUS       DAVHSH010000058        10975 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000058 DAVHSH010000000
VERSION     DAVHSH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.059"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            40..624
                     /locus_tag="VVR08_001750"
     CDS             40..624
                     /locus_tag="VVR08_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEU6075610.1"
                     /translation="MYKNHSLPRERLKTILKGSHGHVGISFDIGKPNRLVFCESFIDL
                     MSYYELHQQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQRLEFLDTVIPSKLLPLIN
                     TIRDTTSYFDNHPDLLTLAVDCDDAGKDFSDKLSQSGFPVFLDFPDNKSGKEKVDWND
                     VLREKKSDLQLMIENAKETLRNQPVRKTSQCLEL"
     gene            675..908
                     /locus_tag="VVR08_001751"
     CDS             675..908
                     /locus_tag="VVR08_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075611.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            905..1288
                     /locus_tag="VVR08_001752"
     CDS             905..1288
                     /locus_tag="VVR08_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEU6075612.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTDSNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTFIDTKNKDNKKLQSIYDAISDLH"
     gene            1326..1601
                     /locus_tag="VVR08_001753"
     CDS             1326..1601
                     /locus_tag="VVR08_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075613.1"
                     /translation="MFTTFFKKNHDNSDVFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     DQESEQVKTESIYREETLDDTLKEAKNQLHKEQLEKNLERFRKDGRK"
     gene            1683..2315
                     /locus_tag="VVR08_001754"
     CDS             1683..2315
                     /locus_tag="VVR08_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HEU6075614.1"
                     /translation="MELTTKQEKQLGQTQWFHATLLRHLESLKSGIDVKFNLGSELDF
                     GPGFYITPDFEQARKFINKQVEVLNRSSSNNNIFDSEEEVGIIVEFRISNFIEIFKNP
                     DYHCHYFAKHKKSESDLDFAEFVVQNRENPDELQHHFDFIYGVQTDDNPTQALARFRQ
                     NEITKEEMLAEFRKPYSFKQLSIHNQSFCDIMKIEKVYQSKTGEELQKWQ"
     gene            2306..2533
                     /locus_tag="VVR08_001755"
     CDS             2306..2533
                     /locus_tag="VVR08_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075615.1"
                     /translation="MAVVSLENNIKLYSSELFQALLKASNYKLDKRIAQTVAEGYARN
                     LDYSDPELMHVGVTSVANNLLTKIKQEYFNV"
     gene            complement(2692..2868)
                     /locus_tag="VVR08_001756"
                     /pseudo
     CDS             complement(2692..2868)
                     /locus_tag="VVR08_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2893..3273
                     /locus_tag="VVR08_001757"
     CDS             2893..3273
                     /locus_tag="VVR08_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU6075616.1"
                     /translation="MKSMGYEVQLALIATKPKLSYLSTLIRYEKLYAINPDQARATPK
                     EHHDFIVNHLVDNTRQLEKLAIFERIQIYQRDRSCVYDSEEDKTSVATVLHDLLFGEW
                     NQVEKEMLKSGEGKLKDLTNRNGC"
     gene            complement(3651..4547)
                     /locus_tag="VVR08_001758"
     CDS             complement(3651..4547)
                     /locus_tag="VVR08_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6075617.1"
                     /translation="MDYKLISTYLDYCKTHKRLSSHTIRAYKNDLMQFYNSNYDNVES
                     YIEELTQSNIKTNTLRRKIACIKVFYNYLKYQHIIEENPFNQLRFQFRTEKILPKTIP
                     YDILKNIFSYLEQRVVISKTDYQKQKAERNLLIISLLLSTGIRISELCHIHLKDINLS
                     NKTLHIIGKGKKERILFLGDQTTFNLLETYINKNGKESNDFLFPGKHSPKPLSEQSVR
                     LILKRIVEQNGLSKTITPHMFRHSFATMLLDNDVDIRYIQQILGHSSISITQIYTHVS
                     HSKQKEILSSFNPMSVIHSEIE"
     gene            4641..5213
                     /locus_tag="VVR08_001759"
     CDS             4641..5213
                     /locus_tag="VVR08_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075618.1"
                     /translation="MTNKKIRVFLSRPNPFTENQNLFIKELIKFLRRHNIECVTLQAA
                     EYTPYEVMNSLSEMIQRSYGIIIVAFGQTFISSGTRKMGAEDNPDFFASKETHLKNKW
                     VTSVYCHIEGILALTYNLPMLSIPQESLTEEGILKKGEYSITSPEFSLETKENILMYL
                     QSEGFQKSFHVWKNLLDDKYNFIKGGEINY"
     gene            complement(5210..6460)
                     /locus_tag="VVR08_001760"
     CDS             complement(5210..6460)
                     /locus_tag="VVR08_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075619.1"
                     /translation="MTSCFVVMGFNTKKIPNTNIEVDLNQVYNNLIKPTILEKELVSV
                     HGKNHFRADEVFSTQSITKTFIEGILKADIVIADITTLNQNAIYELGLRHAMKPKSTI
                     ILCDHHTAKISFFDIAHLPQIRYDSDKLNEVDEVNKVKKLLSEYIDSAIKSDETFTDS
                     PAFESALYRVIINDLIDKTEIQSEEALDKSIAELYDQATELKNSEKYPEAEEIFQQIL
                     ESGYIDEEILAGYLLSSYKKNDSSLANLKMAQQNISKYIDINTTTYHKLLGIYGAIFL
                     RIFYITKNRSDLMSAINYYRLGMNFEDRNIYCARNYCANLLKIALVEKDVEVLKEFYY
                     TSVYTAKTILGSLEKIHRKSSEYDDIWFLSNQEDLMLISGLLSKPINDIEGLTERQKK
                     TINEGSIMLSEDLQRIKTAIVNGN"
     gene            7111..9180
                     /locus_tag="VVR08_001761"
     CDS             7111..9180
                     /locus_tag="VVR08_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6075620.1"
                     /translation="MKLTKVIINNFRSFGESQIIELNNQTVLIGNNSSGKTTVLQALS
                     KLFSDKQNDRIIKKSDFHLPKGSRPGENTRNLFIETIFEFDELDGTPYSQAIPSFFEH
                     FTVSKDGAKPFLRIRLESSWEDDGTVEGSIDTQFYYISSDEDTIRDEDKHRAPRKDLD
                     KIRVLYVPASRTPEKELGNASGSMLSRLVNSINWTEDEINEITDKIDELNNTFLSENG
                     ALTQINNEIQKSWELYHEDNRFSQAELIINSSEMAAALRQIALKFSPTTTEEAFTVSD
                     LGDGLRSIFYFSLVDSILDIELEITKDREENPDNPRFKLIPPVLTILAIEEPENHIAP
                     HHIGKLIKRFKQLGNNDNSQVILTSHSPAIVKRIDPEDLKYLRIENNDRVLQTIVSDI
                     QLPPAIDESYKYIKGAIQAYPELYFAKLVVLGEGDSEELLLPKFFDLLGKEVDSSQIS
                     IVPLGGRHVNYFWKLLNALRIPHITLLDFDNERYGGGWGRIKYISQHLYELNTEFQEW
                     FHTQRLDFNEIGSRGCESIGAQRLINWFNKLEEFNVYFSSPLDIDFLMLQHYKDNYLN
                     TLSPIEGPVVSYNDSDGSSKKVKLSDLDCLDRLQLEGFNKRKEEAIRATLKDKSGHGD
                     SFNEEEKELMIWYQYFFLGRGKPTTHMQFLSSISDDELTRNLPPVFEKIVNSAEELLG
                     DIQHGKE"
     gene            9167..>10975
                     /locus_tag="VVR08_001762"
     CDS             9167..>10975
                     /locus_tag="VVR08_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEU6075621.1"
                     /translation="MVKSEEWFPKGDIILEETALGAVKDVTNCLVIAGPGAGKTELLA
                     QKLDYLFSTNKCVSPKKILALSFKTDAASNLKERVKKRYGDEYASRFTSLTYSAFEKR
                     ILDQFRDVLPEDIRPSRDYLIEDWYTIKELLSMNGINVNGWRMSDIRRYVENIILNNG
                     DNHKFKTDLLKGTQDNKPVLLYRQITKLSTQIIDTNEYIRKALQMTYDFVFLDEFQDT
                     TYAQYDLLKTCFLGSSCKLTAVGDDKQAIMRWAGAKPDIFPDYIRDFNPNEYQLLMNH
                     RSVPKLVEFQKEVHQILNSNHSSIQTNNYPEFQEGEITLFEFENESLEAKLIANDIES
                     KIQGGIRPSEICILAKQKVGIYSFELISILNSKGIKARIENEYQDILKDPTCNLLLDL
                     ISCSQGKRDPLIWENISNFYGNINGIDELTDELILAKSYKEIDNIVSDITYLISNFIP
                     NEESMLKLIDCIIEKIDEKRIISNFSTYNGKSDLDIIVKNFSKLLYIEYSQTQGEWLD
                     TVSSFKGENSIPIMTIHKSKGLEYEVVYFLGLEDSAFWSFNNQPEEDKSAFFVALSRA
                     KSHLIFTYCKLRNNSPQNNRNINEIYSLLTQSNLVDV"
BASE COUNT         3920 a         1535 c         1941 g         3579 t
ORIGIN      
        1 aatcatcgtc acaagctgca ggcagcaagt ctccaaggga tttataagaa tcactctctt
       61 cctagagaga ggttaaaaac gattctaaaa ggaagccatg gacatgttgg aatatccttt
      121 gatattggta aacctaatag actggtcttt tgtgaatcgt tcatcgactt aatgagctat
      181 tacgaacttc atcaacaaag tctaactgat gttcgtttgg tatctatgga aggattaaaa
      241 aggtctgttg ttgcttatca aactttacga ctgatagctg aagaaaatca gaggttggaa
      301 tttttggata cagtaatacc ttcaaagtta ttgcctttaa tcaatacaat tcgtgatacc
      361 accagctatt ttgataatca tcctgattta ttgacacttg cggtagattg tgatgatgca
      421 ggaaaagatt tttctgataa gttatctcaa tcaggatttc ctgtttttct ggatttccct
      481 gataataaat ctgggaaaga aaaagtagac tggaatgatg tccttagaga aaagaaatca
      541 gatttacaat tgatgatcga gaatgcaaaa gagacattga ggaatcaacc agtaagaaaa
      601 acctctcaat gtttagaatt gtgataacaa aatcaagatg ttttagctaa tattagaatg
      661 aaggaggatc gtatatgacc attattgaac gcttagaaga aaaggtcact aggcaagaaa
      721 gtaaggtagc aagagagaca gaaaaactcg ctgcttacaa agaacaactg gagacagcga
      781 tgtttgcgac gttcaaaagg cgtcaaagca ttagtcacat gagttttgaa gaagctcttg
      841 accatgcctt tggtaaagaa agacaattcg atgattctga atttagaaag gatgaaatga
      901 gtgaatgaca aaagattgga attttaatca accattagaa agtaaatcag aaaatcaaga
      961 agatccagat aaaattgcgg ccttatttag aaatcatcaa ggaggtaatg atgtaaatta
     1021 tgaagcagct tttcaaaagc gaaaacaagc acctgtgacg gattcaaatt ctagttctaa
     1081 acccaaagtt acagaggtta gaacaggaaa agagacagat atcactacaa gttatcagca
     1141 acatcttaaa agacttattg cggataacaa tagcgatatt caaagcagtc aaaagaaaat
     1201 tgaagagcta catacattta ttgacacaaa gaataaagac aataagaaat tacagtccat
     1261 ttatgatgcg atttcggatt tacactaagc agtcctgata ggctgctttt tttgagaggt
     1321 tatagatgtt tacaacattt tttaagaaaa atcacgacaa tagtgatgta tttaaaaagc
     1381 tgattcatag actatctgat atgtctgtcc aagatcttga aaaaatagac cgactgttag
     1441 atatcatttt cactccagat caagaatcag aacaagtaaa aacagaatca atttataggg
     1501 aagaaacttt ggacgacaca ttaaaggaag ctaagaatca acttcataag gaacaattgg
     1561 agaagaattt agagagattt aggaaagacg gaaggaagtg aatagtttta tacaattttc
     1621 ttttacttga ataaagtctt gtgttatact tttagtatag actagagaag gaagtaaata
     1681 ttttggagtt gactaccaag caggaaaagc aactaggtca gacgcagtgg tttcatgcta
     1741 cattattgag acatttagaa tccttaaaaa gtggtataga tgttaaattt aatttaggaa
     1801 gtgagctaga ttttggtcct ggtttctata tcacgcctga ctttgaacaa gctagaaaat
     1861 ttattaacaa gcaagttgaa gtattaaatc gaagcagctc taataataat atttttgact
     1921 cagaagaaga agtaggaatt atagtagaat ttcgtatttc aaattttata gaaattttta
     1981 agaaccctga ctatcattgt cactattttg caaaacataa aaagtcagag tcagatttag
     2041 attttgctga atttgtcgtt caaaatcggg aaaatccaga tgaattacaa caccattttg
     2101 attttatcta tggtgttcag actgatgaca atccaaccca agctttagct cgttttcgtc
     2161 agaatgaaat tacaaaagaa gaaatgcttg ctgagtttag aaaaccatat tcttttaaac
     2221 aattatccat ccacaaccaa tctttttgtg atataatgaa aatagagaag gtttatcaat
     2281 caaaaacagg agaggagtta caaaaatggc agtagtatca ttggaaaata atattaaact
     2341 atatagttca gaattatttc aagcactatt aaaagcctct aattataaat tggataagcg
     2401 tattgctcag actgttgcag aaggctatgc tcgtaatcta gattattctg atcctgaact
     2461 gatgcatgtt ggtgtaactt cggttgctaa caatctgctt acaaaaatta aacaagagta
     2521 ttttaatgta tagtatttta aaaagccacc gaaaaaggaa ttactcttta aggtggcttt
     2581 tttagaagta aagtttaggc tagaaaaaca agaagtaacg caccaaaaat ggtgcatttc
     2641 ttttttctaa atgttacggc tctttgtcaa ctgcagtggg ttgaagaaaa gctaagatct
     2701 tgaaaggaca catttcgtcc tttctttttt gatgttcaga gcgataaaaa tccgtttttt
     2761 gaagttttca aagtttcgaa aaccaaaggc atttcgtttg atgagtttaa tgagattatt
     2821 agtcgcttcc aatttggcgt tagaataggg tagttaaagg gcgttgatgt tccaaaggaa
     2881 acagcacaac tcttgaaaag tatgggatat gaagtacaat tagctttgat tgcgacaaag
     2941 cctaagctgt cctatctgag cacccttatc cgttatgaaa aactgtatgc tatcaatcca
     3001 gatcaagcac gcgcaactcc aaaagaacat catgatttca ttgtaaatca tctagttgat
     3061 aatacaagac aattggaaaa actagctatc tttgaaagaa ttcaaattta ccaacgagat
     3121 agaagttgtg tatacgattc agaagaagat aaaacttcag tagcaaccgt tcttcatgat
     3181 ttactatttg gcgaatggaa tcaagttgag aaagagatgc ttaaatcagg agaaggaaaa
     3241 ttgaaagatt taactaatcg aaatggttgt tagatcttga gttttaaaat atagtctact
     3301 tataactttt gttagttgtt taaggtgggc gaaacttttt tagaagcaaa aaacgcatag
     3361 tctcaggtgt tgaaaaactt gaaattatgc gttttcttgt gggaagattt actccatttt
     3421 cttcaggaat tgagattttg cccatctctt ttcattatat ttaaggatac ttgaaagtta
     3481 tattttagaa aaacaattat ggagttctta atacggaata tagtataaat gctgattcaa
     3541 agtggagttt tgcatgcttt ttgcttttgt tgagtataaa atctattaac taaagtcaac
     3601 tacaaacatt aatttaagat gaagtaaact gtaaccttcg gaaatgtctc ttactcgatt
     3661 tcagaatgaa tcactgacat aggattgaaa gaactaagta tttctttttg ttttgaatga
     3721 gatacgtgag tatagatttg tgtgattgat atagaactgt gtccaagaat ttgttgaata
     3781 tatcgaatat ctacatcatt atctagaagc attgttgcaa agctatgtct aaacatatgt
     3841 ggtgtaatag ttttagataa gccattttgt tcaacgattc tctttaaaat taaacgtaca
     3901 ctttgctctg acaatggttt aggcgaatgt tttcctggga ataggaaatc attagattcc
     3961 tttccgtttt tatttatata tgtttctaat aaattgaagg ttgtttgatc tcctaaaaat
     4021 aggatacgct ctttcttacc ttttcctata atatggagtg tcttattgga aagattaata
     4081 tctttgagat gaatgtgaca aagttcagaa attctgatac ctgttgaaag taatagggaa
     4141 ataattagta gatttctttc agctttttgt ttttgatagt cagttttaga tataactact
     4201 ctctgctcta aatatgaaaa aatatttttc agaatatcat acggaatcgt tttaggcaat
     4261 attttttcag ttctaaattg aaagcgtaat tgattgaagg gattctcttc aattatgtgc
     4321 tggtatttta gatagttata aaacaccttt atacaagcaa tttttcttct taatgtattc
     4381 gtttttatgt tagattgtgt caactcttcg atataggatt cgacattatc atagtttgaa
     4441 ttataaaatt gcataagatc attcttataa gctcgaatcg tgtgtgaact caaacgctta
     4501 tgagttttgc aataatctaa gtaagtagaa ataagcttat aatccataaa aatctccttt
     4561 atcaataatc atgctattat aaacctattt gagtgctttg tatagtgata ataaattgtt
     4621 atcggtagga gatagcgaat atgacaaata aaaaaataag agtattttta agcagaccta
     4681 atccatttac agagaatcaa aatttattta ttaaagaatt gattaaattt ttaagacgac
     4741 acaatattga atgtgtaaca ttacaagctg ctgagtatac tccttacgaa gtcatgaatt
     4801 cgttgagtga gatgatacaa aggagttacg gaattataat tgttgcattt ggtcagacat
     4861 ttatttctag tggaaccaga aaaatgggag ctgaggataa tccagacttc tttgcatcca
     4921 aagagaccca cttaaagaat aagtgggtta caagtgttta ttgtcatatt gaagggattt
     4981 tagcgttaac ttataatctt ccaatgctat ctattcctca agaaagttta actgaagaag
     5041 ggattttaaa gaagggagaa tattctataa catcacctga attctcatta gaaacaaaag
     5101 aaaatatatt aatgtacttg caatcagaag ggtttcaaaa aagttttcat gtatggaaaa
     5161 accttcttga tgataagtat aactttatca aaggagggga aataaactat taattaccat
     5221 ttacaattgc agttttaatc ctctggagat cctcacttaa cataatacta ccttcattaa
     5281 ttgttttttt ctgtcgttca gttaaaccct caatatcatt aataggtttt gaaagaaggc
     5341 ctgaaatcag cattagatcc tcttgattgg aaagaaacca aatgtcgtca tattcactag
     5401 atttacgatg tattttttct aaagatccta aaatagtttt tgctgtataa acagatgtat
     5461 agtagaactc ctttaaaact tcaacatctt tctcaactaa ggctattttt aacaggttag
     5521 cacagtaatt ccttgcacaa taaatatttc tatcttcaaa attcatgcct aacctatagt
     5581 aattaattgc agacattaag tcactcctat tctttgtaat ataaaatata cgtaagaaaa
     5641 tagctccata aatacctaat aacttatgat atgttgtggt gtttatatct atatatttac
     5701 taatattttg ctgtgccatt tttaaatttg ctagcgaaga gtcatttttc ttataggatg
     5761 atagtaaata gcctgccaaa atttcttcat caatatatcc actttctaaa atttgctgaa
     5821 atatttcttc tgcctcagga tacttttctg aattcttgag ttccgtggct tgatcataaa
     5881 gttcagctat tgacttgtct aatgcttctt cactttgaat ttcagtttta tcgattaaat
     5941 cgttaattat tacacggtat agagcagatt caaaggctgg actatcagta aatgtctcat
     6001 ctgactttat agcggaatca atatattcag aaagcagttt tttcaccttg ttaacttcat
     6061 ccacttcgtt taacttatca gaatcatatc tgatttgagg taagtgtgca atatcaaaaa
     6121 agctaatctt agctgtgtga tgatcacaca gtataatggt tgatttgggt ttcatagcat
     6181 gacgtagacc taactcatag atagcatttt ggtttaaagt agtaatatct gcaattacaa
     6241 tatctgcttt taatatacct tcgataaatg ttttcgttat actctgtgta ctgaaaactt
     6301 catcagctct aaagtggttt ttaccatgaa cagaaactaa ttctttttct aaaattgttg
     6361 gcttaattag attattatag acttgattca agtccacttc tatatttgta ttaggaattt
     6421 ttttagtatt aaaccccata actacaaaac aactggtcat ttctcaactt tcctcccgat
     6481 aacaatttat tatcactagt ataccataaa gtcattttta gtagcttgat ttgtataatg
     6541 gtttttttag ttagaattaa atgttattgg tcaactataa agtaaaatac tgttttgaaa
     6601 ttatatctaa tacttttgag tcaattacaa acttacaaca actcgagaat tgtgtagttt
     6661 gaaggaaata agtacaagtt tattagaaat gtagcatttt atatgattat caagaaaaat
     6721 tctaatttta gaattatatt ttctattagt tcagaatctg tttttatttt taaatgttat
     6781 aatagtgtta tcaagtaaaa agagcatgct ataattggta acaatataaa attctacgaa
     6841 agacacatgg cctgacaaaa acagatttgc tcgaattgta taaattttac gcaatagccc
     6901 ttagctgtta taaaaacgga acaagtacta tttcaactat ttgctaggaa ttcatagaag
     6961 atgtgtctat gtttcaaaaa tagatcaagg ttaagcttct gtcactcttc aataatgcct
     7021 ttttgggtaa tagagtaggg ttgaggaaga gatgtagaag gtgggacagg aatggttgtg
     7081 tgaattagtt tcaggtaatg gagataagaa atgaagttaa caaaagtaat tattaataat
     7141 tttagatcat tcggtgaaag tcaaattatt gaattaaaca atcaaactgt actgattggg
     7201 aataatagtt cgggaaaaac aactgtatta caagcattga gtaagctgtt ttcggacaaa
     7261 caaaatgata gaataataaa aaaaagtgat tttcaccttc caaaaggttc aaggcccgga
     7321 gaaaatacta gaaacctctt tatagaaact atttttgagt ttgatgaact tgatggaact
     7381 ccctatagtc aagcaattcc atcgtttttc gaacacttta cagtttctaa agatggtgcc
     7441 aaaccatttc tacgaatcag gttagaatct tcttgggaag atgatggaac agttgaagga
     7501 agtattgata ctcaattcta ttatatttca tctgatgaag atactattag agatgaagac
     7561 aaacatcgtg ctcctagaaa ggatttggat aaaattaggg tactttatgt acctgcttca
     7621 agaacgcctg agaaggagtt gggtaatgct tcaggtagta tgttaagtag gttggtaaat
     7681 agtataaatt ggaccgaaga tgagataaat gaaattacag ataaaattga tgagttgaat
     7741 aacacctttt tatctgaaaa tggagcattg actcagatca acaatgagat tcagaagtca
     7801 tgggaattat atcatgaaga taaccgtttt tctcaagcag agttgattat taattcttct
     7861 gagatggcgg cagcacttag acagattgcc ttaaaatttt caccaacaac cactgaagaa
     7921 gcatttacag tttcagatct aggagatgga ctgagatcta ttttttattt ttcacttgtt
     7981 gattcgatac ttgatattga gttagaaatt accaaagacc gtgaagaaaa tcctgataat
     8041 ccaagattta agttgattcc accagtacta actatcctag caatagaaga accagaaaat
     8101 catattgctc cacatcacat tggaaaactg ataaaaaggt ttaagcaatt aggcaataat
     8161 gacaactccc aagtaatttt aacgtcacat tctccagcta ttgtaaaaag aattgaccca
     8221 gaagatttga agtatttaag aatagaaaat aatgacagag ttcttcaaac cattgtttct
     8281 gatatacagc tacctccagc tatagatgaa tcttataaat atattaaagg agcaattcaa
     8341 gcttatcctg aactatattt tgcgaagtta gtagttctag gtgaaggcga cagtgaggaa
     8401 ctgctattac caaagttttt tgatttactt gggaaagagg tagatagctc tcagatttca
     8461 attgtccctt tagggggcag acatgtcaac tatttttgga aattattgaa tgctctcaga
     8521 attcctcata ttaccttgtt ggattttgat aatgagagat acggaggtgg ttggggaaga
     8581 ataaaataca tttctcaaca tctgtatgag ctgaacacag agtttcaaga atggttccat
     8641 actcagagac ttgattttaa tgaaattggg tcacgaggtt gtgaatcgat aggagctcaa
     8701 cgtctgatta attggtttaa taaactcgaa gaatttaatg tctacttttc atcgccttta
     8761 gatattgatt tcttgatgct acaacattat aaagacaatt atctgaatac tttatcccca
     8821 atagaaggac cagttgtttc atataatgat tcggatggaa gtagtaaaaa agtgaaattg
     8881 agtgatttag actgtcttga tagattgcag ttagaaggtt tcaacaaacg taaagaggaa
     8941 gcaataagag ctactttaaa agataagagt ggacatggcg atagtttcaa tgaagaagaa
     9001 aaagaattaa tgatttggta tcaatatttc tttttaggta gaggaaaacc aacaactcat
     9061 atgcaatttt tatcatctat tagtgatgat gaattaacaa gaaatctacc ccctgtattt
     9121 gaaaaaatag ttaacagtgc tgaagaatta cttggagata ttcaacatgg taaagagtga
     9181 ggagtggttt cctaaaggag atatcatttt agaagagact gcattaggag ccgtcaaaga
     9241 tgtgactaac tgtttagtca ttgctggacc aggtgctggg aaaactgaat tactagctca
     9301 aaagttagac tatctattct ctacaaataa atgcgtttct ccgaaaaaaa ttctagcatt
     9361 aagtttcaaa acggatgctg catcaaattt gaaagaaaga gttaagaaac gttatggtga
     9421 tgaatatgct tctcgtttta cctcattaac ctattcggct tttgaaaaga gaattttaga
     9481 ccaatttaga gatgttctac ctgaggatat acggccatca agagattatt tgattgaaga
     9541 ttggtatact ataaaagaac tactctctat gaatggaatt aatgttaatg gatggagaat
     9601 gtcagatata agaagatatg tcgaaaacat catacttaac aatggggata atcacaagtt
     9661 taaaactgac ttactaaaag gaacacaaga taataagccg gtcctcttgt ataggcaaat
     9721 aacaaagttg agtactcaaa taatagatac taacgaatac atccgtaaag cacttcaaat
     9781 gacatacgat tttgtatttc tagatgaatt tcaggatact acatatgccc agtatgattt
     9841 attaaaaact tgttttttag gttcgtcttg taaattaaca gcagttggag atgataagca
     9901 agccattatg agatgggcag gtgcaaagcc tgatattttt ccagactata ttcgagactt
     9961 taatccaaat gaatatcaat tgttgatgaa tcaccgctct gtacctaagc ttgtagaatt
    10021 tcaaaaagag gttcatcaga tattaaatag taatcacagt tctattcaga caaataatta
    10081 tccagaattt caagagggtg aaataacatt atttgaattt gaaaatgaaa gtttagaagc
    10141 taagttaatt gcaaatgata tagaatcaaa aattcaagga ggtatacgac catcagaaat
    10201 ttgtatccta gcaaaacaaa aggttggtat ttatagtttc gaattgatat ctatattaaa
    10261 tagcaaaggg attaaagcaa gaattgaaaa tgaatatcag gatattttaa aagatcctac
    10321 gtgtaaccta ttattagatt taatatcatg cagtcaagga aaacgagatc ctttaatttg
    10381 ggaaaatatt agtaattttt atggaaatat caatggaata gatgagttaa ctgatgaatt
    10441 aattttagca aaatcctata aggagattga caatatagtt agtgatatta cttacctaat
    10501 ttcaaatttt attcccaatg aagaaagtat gctaaaatta attgattgta ttattgaaaa
    10561 aatagatgaa aaaagaatta tttccaattt ttcaacatac aatggaaaaa gtgacctaga
    10621 tatcattgtc aagaactttt caaagttatt atacatagaa tattctcaaa cacaaggtga
    10681 atggctagat acagtctcta gtttcaaggg tgaaaactca attccaatta tgactatcca
    10741 taagagtaaa ggattagaat atgaggtagt ctattttcta ggcttggagg attctgcatt
    10801 ctggagtttt aataatcagc cggaagaaga taaaagtgca ttctttgtcg cactttcaag
    10861 agcaaaaagt cacttaatat tcacatattg taaattgaga aataatagtc cgcaaaataa
    10921 tagaaatatt aatgagatat attcattgct gactcaatcc aatttagttg atgtt
//
LOCUS       DAVHSH010000059        10946 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000059 DAVHSH010000000
VERSION     DAVHSH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.060"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            11..733
                     /locus_tag="VVR08_001763"
     CDS             11..733
                     /locus_tag="VVR08_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6075622.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            730..1578
                     /locus_tag="VVR08_001764"
     CDS             730..1578
                     /locus_tag="VVR08_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6075623.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1610..2539
                     /gene="psaA"
                     /locus_tag="VVR08_001765"
     CDS             1610..2539
                     /gene="psaA"
                     /locus_tag="VVR08_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU6075624.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2662..3153
                     /gene="tpx"
                     /locus_tag="VVR08_001766"
     CDS             2662..3153
                     /gene="tpx"
                     /locus_tag="VVR08_001766"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU6075625.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3249..5957)
                     /locus_tag="VVR08_001767"
     CDS             complement(3249..5957)
                     /locus_tag="VVR08_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6075626.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5959..6660)
                     /locus_tag="VVR08_001768"
     CDS             complement(5959..6660)
                     /locus_tag="VVR08_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075627.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNSDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6910..9321)
                     /locus_tag="VVR08_001769"
     CDS             complement(6910..9321)
                     /locus_tag="VVR08_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6075628.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYGFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSEANKINLWARLGDGNRAHKLLAEQLKTSTLQNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(9374..10066)
                     /locus_tag="VVR08_001770"
     CDS             complement(9374..10066)
                     /locus_tag="VVR08_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU6075629.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10601..10936)
                     /locus_tag="VVR08_001771"
     CDS             complement(10601..10936)
                     /locus_tag="VVR08_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075630.1"
                     /translation="MGGILLLICPFVLLGTAVNTAATTLNGGATAGAFSGVVLLLNAL
                     KIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILAIIGGSLFLA
                     TLKKFKSEE"
BASE COUNT         3190 a         2519 c         2056 g         3181 t
ORIGIN      
        1 atacaagttt atgatacgta tcgaaaacct cagtgtctcc tacaaagaaa cgttggcact
       61 taaggatatt tcactagtgc tccatggacc aacaattacc ggcatcattg gtccaaacgg
      121 cgctgggaaa tcaacactat taaaaggtat gctgggaatt atcccacatc aaggtcaggc
      181 atttctcgat gacaaggaag ttaaaaaatc cttacaccga attgcctatg tcgaacaaaa
      241 aatcaatatc gactacaact ttcccatcaa ggtcaaggaa tgcgtctcgt taggactatt
      301 tccctctatt cctctctttc gaagtttaaa ggctaaacat tggaagaaag tgcaagaggc
      361 ccttgaaatc gtcggcctag ctgactacgc tgaacgtcaa attagtcaac tgtctggagg
      421 tcaattccag cgggtcttga ttgccagatg tttggtgcag gaagccgact atatcctctt
      481 ggatgaaccc tttgctggga ttgactctgt cagtgaggaa atcatcatga atacgctgag
      541 agatttgaaa aaagctggga agacggttct catcgttcac cacgacctca gcaagattcc
      601 ccactacttc gatcaagtct tacttgtcaa tcgagaagtg attgcctttg gtccaacaaa
      661 agaaactttt accgaaacca atctaaaaga agcttacggt aatcaactct ttttcaatgg
      721 aggtgaccta tgattgcaga atttatcgat ggattgcaaa aattccattt cctacaaaat
      781 gccttgataa cagctattgt cgtcgggatt gtagctggag ctgtgggatg tttcattatt
      841 ctacgcggga tgtcactcat gggagatgcc atttcacatg ctgtcttacc aggtgtagcc
      901 ctctccttca tcttgggcct tgacttcttt atcggagcca ttgtctttgg attgctagct
      961 gccatcatca ttacctacat caaaggaaac tcgattatca aaagcgatac cgccatcggc
     1021 attacctttt cttctttctt agccctcggt atcatcttga ttggtgtcgc taaaagttca
     1081 actgaccttt tccatatcct ttttggtaat atcctggccg tccaagatac ggatatgttt
     1141 attactatgg gtgtgggggc agccatcctc ttgttaatct ggattttctt caagcaactc
     1201 ttgataactt cctttgatga actcttggct aaagccatgg gaatgcctgt caatttctat
     1261 cactaccttc tcatggtact cctgactctc gtgtctgtga cagccatgca aagtgtcgga
     1321 actatcctga ttgtagccat gctgattacc ccagctgcaa ctgcttatct gtatgctaat
     1381 agtctgaaaa gcatgatttt cctttcctca accttcggag ctactgcttc agttttggga
     1441 ctctttattg gctatagttt taatgttgcg gcaggttcta gtatcgtgct tacagctgct
     1501 agtttctttc tcattagctt ctttatcgct cccaaacaac gatatttgaa actgaaaaat
     1561 aaacatttgt taaaataagg ggcaaagccc taataaattg gaggatctaa tgaaaaaatt
     1621 aggtacatta ctcgttctct ttctttctgc aatcattctt gtagcatgtg ctagcggaaa
     1681 aaaagataca acttctggtc aaaaactaaa agttgttgct acaaactcaa tcatcgctga
     1741 tattactaaa aatattgctg gtgacaaaat tgaccttcat agtatcgttc cgattgggca
     1801 agacccacac gaatacgaac cacttcctga agacgttaag aaaacttctg aggctgattt
     1861 gattttctat aacggtatca accttgaaac aggtggcaat gcttggttta caaaattggt
     1921 agaaaatgcc aagaaaactg aaaacaaaga ctacttcgca gtcagcgacg gcgttgatgt
     1981 tatctacctt gaaggtcaaa atgaaaaagg aaaagaagac ccacacgctt ggcttaacct
     2041 tgaaaacggt attatttttg ctaaaaatat cgccaaacaa ttgagcgcca aagaccctaa
     2101 caataaagaa ttctatgaaa aaaatctcaa agaatatact gataagttag acaaacttga
     2161 taaagaaagt aaggataaat ttaataagat ccctgctgaa aagaaactca ttgtaaccag
     2221 cgaaggagca ttcaaatact tctctaaagc ctatggtgtt ccaagtgcct acatctggga
     2281 aatcaatact gaagaagaag gaactcctga acaaatcaag accttggttg aaaaacttcg
     2341 ccaaacaaaa gttccatcac tctttgtaga atcaagtgtg gatgaccgtc caatgaaaac
     2401 tgtttctcaa gacacaaaca tcccaatcta cgcacaaatc tttactgact ctatcgcaga
     2461 acaaggtaaa gaaggcgaca gctactacag catgatgaaa tacaaccttg acaagattgc
     2521 tgaaggattg gcaaaataag cctctgaaaa acgtcattct catgtgagct ggcgtttttt
     2581 ctatgcccac atttccggtc aaatcattgg aaaattctga ctgtttcaga tacaatggaa
     2641 gaaaaaagat tggagtatcc tatggtaact tttctcggaa atcctgtgag ctttacaggt
     2701 aaacaactac aagtcggcga caaggcgctt gatttttctc ttactacaac agatctttct
     2761 aaaaaatctc tggctgattt tgatggcaag aaaaaagtct tgagtgtcgt tccttctatc
     2821 gatacaggca tctgctcaac tcaaacacgt cgttttaatg aagaattagc tggactggac
     2881 aacacggtcg tattgactgt ttcaatggac ctaccttttg ctcaaaaacg ttggtgcggt
     2941 gctgaaggcc ttgacaatgc cattatgctt tcagactact ttgaccattc tttcgggcgc
     3001 gattatgccc tcttgatcaa cgaatggcat ctattagcac gcgcagtctt tgtcctcgat
     3061 actgacaata cgattcgcta cgttgaatac gtggataata tcaattctga gccaaacttc
     3121 gaagccgcaa ttgcagctgc taaagcccta tagaaaaaat cctctgtcac aaagagttcc
     3181 ctgctctttg aaacggagga tttttgaata ttagtaaata gaagttcaat cagctaaaaa
     3241 taactacctt actctacaga tttcagggct tctaacatgt caacctttct cagataataa
     3301 ttgacgaaga aaccaagcaa ggtcaaaatg atgcttactg ctgccactgg gattacatag
     3361 acttcccagc ctacctgcgg ataaaagaga atagtcgcag gcgaaatcat ttgaatcaaa
     3421 aattggtgta aatagaaacc agctaccaga ccaagtacga ttcccacaag ggacagcaca
     3481 atcgtctcac ggtaaatgta gagggtgact tcattattat gaaaaccgag aaccttgata
     3541 gtggagagtt cacggattct ctcagctacg ttgatattgg tcagattgta aaggatgaca
     3601 atagctaata gaaccgatac gatgaccaag atggtcatgg tctgattgag tgagctagcg
     3661 atagagtcga agagtcgaat ggctgaagca ttttggacaa cgctggacac cgcagattga
     3721 ttcataagca agcccgcctg actttcgata ctagttgcac tggtatccct taatgagacc
     3781 agataagtgt tggcttgggg tagctgtccg taaagttgct catagctagc ctgactcata
     3841 taaataaagt gaccaacgta gttctcagta atagcagcga cctttagttc cttaccttca
     3901 atttctaaag tctgcccaac cttgacacct gccagctggg cgagtttagc tgtaataacg
     3961 atgccatctt ttaatgtcag ctcctgctga tgatgttgaa gatggataaa gggagtcaaa
     4021 tcttccttct ctatcatcat aagagtaatg ttttgaagac cagccttgcc tttgaaatcc
     4081 ttgtctagcg ttttagaata gattttctgg taggctagta tctcctgccc tttcaatact
     4141 tctgctagct ctaccttgtc ctgattggtc gcactaggat tttcagagac aagcatctga
     4201 tactgttgga tttgttgaaa ctgtttagac ggaactcctg ctacagaaga ttggattccc
     4261 aaacctgcaa agagcagagc tacagaacct gccacaccaa agattgtcat caacattctc
     4321 tgcttataac gaaagatgtt gcgggctgtt accttatgag taaaactgag acgacgccag
     4381 ataaaaccga tacgctccaa taagatttta gctcctttga caggaggttt aggaagtaga
     4441 agctgggctg cttcggcatg aagttccctc caagccacca gataggctgg taacacactc
     4501 gccaacaagc tcaagacaag agctagtaag ctataggtcc aatagaactg aatctgggtt
     4561 tctcccacca ccatgccttt tgtaatgaca cttgaaatta cactggctag caaataatga
     4621 ccaagtatac tacctagagc cgttccgaca gtcccagcta ctagtccata aaggagaaac
     4681 ttggtgataa tatccttact acggtaaccc aaggccttaa aaatccctgc atgagttcgc
     4741 tcttcgtcta caaagcgagt catggtcgta aaggtcacca tggctgctac ggcataaagt
     4801 accacaggaa agatattgcc cactgctcga atactggatg aagcattgct atacataaga
     4861 tagccctgac cacctggcat ggtctgacga ttatagacct gataccttgg ctccgccaaa
     4921 tcgtccaaga cttgctgatg tttttctaat ttttcctttt cttgggctag attttgttca
     4981 gcttgcttta gtttggcctc ttccttgccc aattcctgct tggcttgggt aagttgagca
     5041 ctagcctgct ctctctgaac ttgaggaaac aaggctagtt gactttcttg agcctgtata
     5101 cgagcttgag cagctgctaa acgacgcttg ccttcctgca aattagtctg agccttgtca
     5161 agggtctctt gccccttgtc tagagactct tgtccttctt ttttcaaaag ttgcagacgt
     5221 accttgccat tatctgataa aatttgttca agctcttcct gatgttgctt ggatttttct
     5281 tcataagctg atgaaaaggc atttaaacct gctaaatctt gatatttcaa acgagctata
     5341 ttgtagactt tctgatcaaa ctgactaggt aaaatcaccc cataggctgt cagagtccca
     5401 cttccacttc ctgcgtagcc catatctcgc tgggagagga tttcagccga atccacaaaa
     5461 ccagtaatgg tataagtatg gtcttttaaa gaggaatgac cctcttcttt ttctttaaaa
     5521 ctaatctcct gtcccacgct gtattggcct tgcaaatgag tggccaaagc gatttccttg
     5581 tctgactgag gaagtcgtcc cttccttagc tgaaaggttg aaattcgctc tggtttggag
     5641 tacagtcgaa tggcatcctg cccattatcc atagtcacat ctgtcaaata gccaaactcg
     5701 acctctgcgc cctccgtctg ttttagttct tcttggtctg cttgatccaa gccatagtta
     5761 gacatgactg ccaaatccaa ggtttgagca gttgttaaat aagcattagc tgtcgcctcc
     5821 atgttgggac tggttacttt gaggcctact aaggctagag atcccaacat catcaggatc
     5881 aagatggata aaaaacgccc cttggagcct gtgaaggact gaattaagtc cttccaataa
     5941 gtttttcgct tgatcatgct agtactccaa actgtcaata tcctgaggat gctggttgag
     6001 caccacatcc ttgacactgg catcgtgcat atgaatcacg cgatcagcaa tgggcgccaa
     6061 agctccatta tgagtcacga tgatcaccgt cgctcccttt tgacgagaca tgtcttggag
     6121 aattttcaaa acctgcttgc ccgtctgata atccaaggct ccagtaggtt catcacaaag
     6181 aagaatttta ggatttttgg ctaccgcgcg tgcaatggag actcgctgtt gctcccctcc
     6241 agaaagctgg gctggaaagt tattgagacg atgagccaga cctacatctg tcaagacctg
     6301 atcagaattc aaggcatctg tcacaatttc agaagccagt tccacatttt ccttagctgt
     6361 cagattagaa actagattat aaaactgaaa aacaaacccc acatcatttc tacggtaatt
     6421 ggtgcgctgg tgggaactat aatccgcaat attaacacca tcaatccaga tttccccttc
     6481 atcattggta tccattcccc caagaaggtt aagaactgtt gacttgcctg cacctgaagc
     6541 accaaggata ataaccagct cccccttttc aatctcaaaa ttcacatcac gattggccac
     6601 aatctccgtg tccccaacct gataacgctt gtaacagtgt ttcatctcaa tataagccat
     6661 cagacccacc ctctatcaaa caaattatac tcctcgaaaa tctctcttca aaccacgtca
     6721 gcttccatct gcaacctcaa aacactgttt tgagcaacct gcggctagct tcctagtttg
     6781 tgctctttga ttttcattga gtattacttc ctattatcat tataacgttt tttcaactag
     6841 ttgaaaactg cttatattct taaatcctta ttaaaaggca gtttcaaatt actgccttat
     6901 aacatcttct taaaaataaa attgaacaag atcaccttct gctgttgcca ccgaaataca
     6961 atctttcccc atgcatttcg cttttatttt ttcttgattc attttaatca cactcttctc
     7021 aatatctgga taagaaactc gcaaatctcc tccactcctt gataaaatgg tcaactgtaa
     7081 gagtttttta tcttcccagc tcatgctcac ttcaaaatgt ccacgtgcca ttaagcctga
     7141 aacagaacct gttgaccaag catcaggtag ggcagctaga ggtaccagat aagctgcatg
     7201 agactggagt aacatttctg ccatgccact agtagcacca aaattaccat ctatctgaaa
     7261 aggaggatgg ctacaccaaa gattttgcaa ggtggatgtc tttaactgct ctgccaataa
     7321 tttatgggct cgattgccat ctcccaaacg cgcccagaga ttgatcttat tagcctcgga
     7381 ccagcctgtg ccgccatctc cacgatcatt gaggctagca cgcgccgctt caatatactc
     7441 ttgtcccttg tagctaaaga gattgccagg atagagtccc actagatggg aagcgtgccg
     7501 atgctgggcc tccactttct cattttgaaa atactgctct tcctcctcat accactccct
     7561 gattcgacca gattgagtga tttgcaaagg atttagtaaa tcagacttct ccttaacctc
     7621 agtcaacaag tcctcatcca gtcccaattc ctgagcagcc tgaataaaat catgaaataa
     7681 ctgccaaatc agagattggt cataggtatt gccaatcgaa atcggcccat gttctgggga
     7741 ataagacgga gaagacaccc aacgctgcgc ctgctgatcc ttatgtaaaa aggcattcca
     7801 aaaacgaacc gtttccctca acatgggata aattttctcc ctgagatagt cttggtccct
     7861 ataaaatgaa taggcttcat aaacggtttg catcatccac gcattggcag ctggtgacca
     7921 accccaatag taatcccaac caggtgccgt ccaaccaaag ggagtcgctt gagtatgaac
     7981 caaccaacca ttctcctcac ctttctgaga gacgattcct gcatacttta cagccgctag
     8041 acgaccatag acacgcaaat catctacata gttgatgact ggaaagaccg tctctaggag
     8101 attggtaaca taggctggcc aataattcat ctgcagattg acatttaagt gatagtccga
     8161 attccaagga ggattgtcga ccgcattcca gactccctgt aggttagctg gtagagcatc
     8221 tgggcagtct ctggacgaac taatcaataa ataccgtcca tactggaaga acagctcctc
     8281 caaagcctgc ccttcttgtg gcttataatt ttttaacaaa tcatctgtag tggatgcgtc
     8341 aacatcagct tccaaatcca attgaacacg ctggaataag gcttggtagt cctcgatatg
     8401 ccttgatttc aattgggtat agcccttttc tttagctgtg tccaccaagt ctatcacctg
     8461 ttgctctaaa tctagtttct tgcgataatt gctagcagga ttttgggcaa aatccgtctt
     8521 agcggccaag aagagattgg cataactggc tcctgatatc tgaaccctat ctgaccaaac
     8581 tctaatatct ccatccgttt cccaagctag ataactagca aaccgcagat cattatcctt
     8641 aactcttccc ttcatcaaga tatgagaatc agtaatatcc aacttacact ccttgtaatc
     8701 agatttttcc tgctcatact ttccatcaga agccaaatca caggtcaagg atagttctat
     8761 agtaaaatct agagtttcca acccttcctt agtaaaacat tgaaccaaga gatcatctgg
     8821 aaaactcgca aaagctttac gttcaaatcg cgttccctta tagacataag aagtcgtcgc
     8881 aagtgcctta ctaatattca gctgtctctg atagtccgtc acctgagaca aagtcgtacc
     8941 ttgctggctg aactcaatgt gaatatcccc aaaagacaga taggtcccat attgactcgt
     9001 ttttggccca attaggtgct gctcagccag ttccttagcc agattgtaat ctctcttctc
     9061 caaagcctgc cgaatctcag ctaaaaaacc atactgatcc tgaagatttc caccctgata
     9121 atctgaacta tcaggaagtg gacctccaga ccagagactt ttttcattaa attgaatccg
     9181 ttcagcccct ataaggccaa atacttttgc tcctaaagaa ccattgccta tcggtaaagc
     9241 ttcttcttcc caacccatgt aagtggttga agccggttgc ttgtaggcca gtacataatc
     9301 ttgtttttta ttccttatca tacttccata ctaacataaa aagcctagaa atcaatccta
     9361 ggcttacaat tttttatttt ccaaggtagt attcagaaac aacgttcaat ttttcgtcga
     9421 attcgaatac caatggtggg aagttaggga tttccacgtc catgatctca tcatctgaca
     9481 aacctttgat gtgttttaca agggcacgga ttgagttacc gtgagctcct acgaatacgt
     9541 ttttaccatc tttaagagct ggagcgattt tatcttccca gaatggaaga gcacgttcca
     9601 aagtcacttt caagttttca gcatctggga taactgagtc gtcaagtgaa gcgtaacgac
     9661 ggtctgtgtg agctgagtgc tcatcatcac ggtccatgtt tggaggcaat acatcgtatg
     9721 aacgacgcca gatgtgaact tgctcatcac caaattgttc agcagcttca gctttgtttt
     9781 taccagtcaa accaccgtag tgacgttcgt tcaagcgcca tgatttttca actggaaccc
     9841 acaattggtc agaagcttca agagccaagt tagttgtttt gatagcacgt ttcaatactg
     9901 aagtgtaagc ttggtcaaat tcgataccag cttctttgat caatttacca gcatcaatcg
     9961 cttgttgtgt acctttttca gacaaatcaa catcagccca accagtgaaa aggttagctt
    10021 tgttccattc agactcaccg tggcgagcaa aaaccaattt taccattaga tggattctcc
    10081 tttaaatttt ccgaggtttc ccctcgttta tctattctat tttacacaat ttttcacaaa
    10141 aaagctagtc aaaaccaaaa aggaaaagac tgtttgacaa tgtttggcaa tcacattgtt
    10201 tttggttgtt tctattctat cttcattatt taaccttttt ttctgcgcat cgaataattt
    10261 ttgagttgac tcttttagtt tagtaaacga gtcattattt tccatagctg tgcctttgaa
    10321 accttcctca gctttagtaa aataatcatc aaaaatattt ttataaagat ctatataatc
    10381 tgcataagtg cgtattgatt caatcgcatc gtctgttaca accggtgtat cgaaagtgat
    10441 tgtttctttt gaactattgg atgttgctac tgtcttctca tcattacttg ttgaagtatt
    10501 ctttgaactt tatgttccac atgcaactag aagagaaaga gataatagag ctactcctat
    10561 accgataaac ttttttgttc ttttcatgct aaaatacctt ttattcttct gatttgaatt
    10621 tcttcaatgt tgcaaggaat agagatcctc cgataatagc aagaatcccc ccaacccatc
    10681 ctaagaatgg aatgagacta acttcaccag aaacaatcat tagtacagac ggagctgcac
    10741 ctacacgctt atctccttta tagtaaacaa tagcaatgat accaagaaca agatttgcaa
    10801 tcttcaaggc attcaagagt aagacaacac ctgaaaaagc ccctgcagta gctcctccat
    10861 taagagttgt agcagctgta tttaccgctg ttcccaacaa gacaaaagga caaataagaa
    10921 gtaaaattcc tcccacaaga ccgacg
//
LOCUS       DAVHSH010000060        10750 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000060 DAVHSH010000000
VERSION     DAVHSH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.061"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            378..1256
                     /gene="truB"
                     /locus_tag="VVR08_001772"
     CDS             378..1256
                     /gene="truB"
                     /locus_tag="VVR08_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU6075631.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            1497..1799
                     /locus_tag="VVR08_001773"
     CDS             1497..1799
                     /locus_tag="VVR08_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6075632.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            1907..2545
                     /gene="udk"
                     /locus_tag="VVR08_001774"
     CDS             1907..2545
                     /gene="udk"
                     /locus_tag="VVR08_001774"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU6075633.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            2673..4013
                     /locus_tag="VVR08_001775"
     CDS             2673..4013
                     /locus_tag="VVR08_001775"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU6075634.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEVKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            3991..4203
                     /locus_tag="VVR08_001776"
     CDS             3991..4203
                     /locus_tag="VVR08_001776"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU6075635.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            4200..5075
                     /locus_tag="VVR08_001777"
     CDS             4200..5075
                     /locus_tag="VVR08_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU6075636.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            5068..5883
                     /locus_tag="VVR08_001778"
     CDS             5068..5883
                     /locus_tag="VVR08_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU6075637.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            5876..6307
                     /locus_tag="VVR08_001779"
     CDS             5876..6307
                     /locus_tag="VVR08_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6075638.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            6314..7981
                     /gene="recN"
                     /locus_tag="VVR08_001780"
     CDS             6314..7981
                     /gene="recN"
                     /locus_tag="VVR08_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU6075639.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            7983..8711
                     /locus_tag="VVR08_001781"
     CDS             7983..8711
                     /locus_tag="VVR08_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU6075640.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDYPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            8790..10613
                     /gene="lepA"
                     /locus_tag="VVR08_001782"
     CDS             8790..10613
                     /gene="lepA"
                     /locus_tag="VVR08_001782"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU6075641.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         3192 a         1927 c         2610 g         3021 t
ORIGIN      
        1 ttacttaaca acttataacc agaaattatc tttacgaggg atgaattata aattgaatca
       61 tgaagaactt aacaattttg atttgttgaa aaaaatgttt ctgaaattaa tggagaccga
      121 taaaatagag aatgatattt tttatttaga tggcatcaaa agtatactcc cattattatc
      181 tttagatgac agacgaaatg tattacaaca tattcaaaaa cagaacaatt gtcctcctcc
      241 agagattgag gaattacaaa gaattatagt taattaaatt ttgtaaaaaa gagaataaaa
      301 ggtagacgac gcctcagtaa aaattggccc ggaaaaaagc gaagttcgaa gcactgaagg
      361 gggagtagaa agcaaaaatg aacggtatta tcaacttaaa aaaagaagca ggaatgacct
      421 cgcatgatgc ggtttttaaa ctgcgtaaga ttttgggaac caagaaaatt ggtcatggtg
      481 gaaccttgga tccggatgtg gtgggtgttt tgccgattgc ggttggcaag gcgacacgca
      541 tggtcgagtt tatgcaggac gagggtaaga tctatgaggg ggaaattact ctgggttatt
      601 ccacgacgac tgaggatgct agtggggaag tgatcgcaga aacccctgtt ttgtctccct
      661 tggatgaaaa gcttgttgat gaagcgattg ctagcttgac tgggcctatt acccagattc
      721 cccctatgta ttcggcagtt aaggttaatg gtcgcaagct ctatgagtat gcgcgtgctg
      781 gtcaggaagt ggagcgtcca gaacgtcagg tgaccattta tcaatttgag cgaacaagtc
      841 cgatttctta tgatggccaa cttgctcgat tcacttttcg tgtaaaatgc agtaaaggga
      901 cttacatccg tactttgtca gttgatttgg gtgaaaagct tggttatgcg gctcatatgt
      961 cccatttgac tcgtactagt gctgctggct tacaattaga agacgctctt gccttggagg
     1021 aaattgctga aaaagtagag gctgggcaat tagattttct ccatccttta gagattggga
     1081 caggtgacct tgtcaaagtt ttcctaactc cagaagaggc tacagaagtt cgctttggtc
     1141 gttttattga gctagaccaa acggacaaag aactggctgc ctttgaagat gataaattgt
     1201 tagccattct agaaaaacgg ggcaatctct ataagccaag gaaggttttt agctagatcg
     1261 tttaggaata aaaatcgggt gatagataac aattgcttga taaaacccca tactaatagt
     1321 agaatggttt tgggaattat aatattccaa ttgttgcgag ttgtaggtac tcaaataatc
     1381 tatatagaaa tttagaggtg tgaaatgaag caatttaaaa ttctttcaga taaatattta
     1441 gagtccatta caggttctgg tgggaactta ggcccaggat ttggtgtgat aattccatga
     1501 tgcgaaatga gtttcgagaa agggtggagc aacttcttca acaaaaagaa ataaatgaaa
     1561 atagtgagtt gagtcacctg tttcgtcttg ctatacaaaa tttagacaga aatgaaaaat
     1621 accaatcggt catggccaat ttgagtcaag ggttgtcact ttacctcatg acgcatcatt
     1681 accaggcacc taagtctgtc attgattttg gtttatggat tgccaaagct cctagccagg
     1741 aaagagggag actggctttc ttgcagatgc ttgctcaaac cctacagggc tttcgttaaa
     1801 actgtcgaac atcagaggga atactctggt gttttttgct gatgagacta taaattttgt
     1861 aaaaaatgtg atagaataga cgacggataa aataacggag gatagcatgc aaaatagacc
     1921 aatcattatt ggagtgacag gtggttctgg tggtggtaaa accagtgttt caagagccat
     1981 tttatcgcat tttcctgatg aaaagatttc catgattgag catgattcat actacaagga
     2041 tcagtctcat ttgacctttg aagagcgtgt caaaaccaac tatgaccatc cttttgcctt
     2101 tgatacagac ttgatgatcg agcagattaa ggaattgttg gcagggcgtc cggtggacat
     2161 cccgacctac gactatacag agcatacacg gagtagcaag acctatcgtc aggagcctca
     2221 agatgtcttt atcgttgagg gcattttggt cttggaggac aagcgtctgc gcgatttgat
     2281 ggatatcaag atttttgtgg atacggatga cgatgtgcgc attattcgtc gtatcaagcg
     2341 tgatatggag gagcgtggcc gtagccttga tagcgttatt aaccagtact taggtgtggt
     2401 caaaccaatg taccaccagt ttatcgagtc aactaagcgt tatgctgata tcgtcattcc
     2461 tgaaggggtt agcaataccg tggctatcga cctgttgacg accaagattg caaagatttt
     2521 ggaagaagct cgaaacagca aataatcaca tgtggaggcc ttgcctcctt tttctatttt
     2581 tccctcataa tggtacataa atggagattt ttaggcatat ttttggtata ataataccca
     2641 tgaaagagca agtaaatgaa tagtaggtgg agatggaaaa gtatttatcg gtaacaactt
     2701 tgaccaagta tctgaaaatg aaattcgata aagacccata cttggaacgg gtctatttaa
     2761 ctggtcaagt ttccaacttt cgtaaacgac ctactcacca atatttctcc ctaaaggatg
     2821 accatgcagt tattcaagcg accatctggt ctgggattta tcagaaatta gggtttgacc
     2881 tggaagaagg aatgaagatc aatgtgattg ggcgtgtaca ggtttatgaa ccaagtggta
     2941 gctactccat catcattgaa aaagctgagc ctgatggggt tggggcgctt gcgattcagt
     3001 ttgaacaact taagaaaaaa ttgacagaag aaggcctgtt tcaagaacgc ttcaagcaag
     3061 ctctgcccca attttctaag agaattgggg tagtaaccag ccgtagtgga gccgttattc
     3121 gagatattat cacgaccgtc agcaggcgat tcccaggtgt tgacatcctt ctttatccga
     3181 ccaaggttca aggtgaaggg gctgcggagg aaattgctag aaatattgcg cgtgctaatc
     3241 aacgggatga tttggatttg ctcattattg gtcgtggagg tggttctatt gaggatctct
     3301 gggcctttaa cgaagaaatt gtggtacgag ctatttttga atctcgtttg ccagttatct
     3361 ctagtgtggg gcatgagacg gatgtgacct tggcagattt tgtggcagat cgacgcgctg
     3421 caacgccaac agcggcggct gaactggcaa cacctgtgac caagttggat gtattagctc
     3481 atttgcaaaa tcaggaaaaa cggatggtaa cggcagtccg aaatgttcta tctaagaaac
     3541 aagaggcttt gaaaaaatgc agtcagtctg ttatctttag acaacctgag cgcttgtatg
     3601 acggttattt gcaacgcttg gaccaactgc aactgcgttt gaaacaaagt ttgcgaactc
     3661 ggatttctga taacaaacaa ttagttcaag caagaactca tcaattagta caattatcac
     3721 ctgttaccaa aatccaacgc tatcaagacc gtttaggaca gttggacaag ctcttaggta
     3781 gccaaatggc gttagtttat gacgccaagg ttgctgaggt caagcgactt tcggaagctt
     3841 tgctcatgtt ggatactagc cgaatcgtgg cgcgtggtta tgctattgtc aaaaaagaag
     3901 agtccgttgt agattcggtt gagagtttga agaaaaaaga ccaagtaacg cttttgatgc
     3961 gagatggtca agtagaatta gaggttaaag atgtcaaaac aaaagaaatt tgaggaaaat
     4021 ctagcagaac tggaaaccat tgtccaaagt ttggaaaatg gtgaaattgc tctggaagat
     4081 gcgattactg cctttcaaaa gggcatggtc ttgtcaaaag agctccaagc tacgctggac
     4141 aaggctgaaa agaccttggt caaggtcatg caagaagacg gaacagaaag tgattttgaa
     4201 tgaaaaagca agaaaaatta gctcttgtcg agtcggcttt ggaagatttt tatggagacc
     4261 agcagtttgc ctctagttta cgggagtctg ttctctattc tattcatgct ggtggcaagc
     4321 gtattcggcc ttttctcttg ttagaagttc tggaagcctt gcaggttacc atcaaacctg
     4381 ctcacgcgca ggtagctact gccttggaga tgattcatac agggagcttg attcacgatg
     4441 accttcctgc tatggatgat gacgattatc gaagagggcg gttaaccaat cacaagaaat
     4501 tcggtgaagc tatggccatt ttggctggag atgccttatt cttagactca tatgccttga
     4561 ttgcgcaggc agatttgcca agtcagatta aggtggactt gattgccaac ttatcccttg
     4621 cttcaggtag tctgggtatg gtggcagggc aagttttgga tatggagggc gaacaccagc
     4681 acttgtcttt ggaagaactt cagactattc atgccaataa gactgggaag ttactagcct
     4741 atcccttcca agcggcagct attatagctg aattgtcacc tgaaatgcag gtgaagctga
     4801 aaactgtggg tgaattgatt ggacttgctt ttcaagttag agatgatgta ctggatgtga
     4861 cagctagttt tgaggaaatc ggcaagacac ctcaaaagga tctgcaggca gaaaaatcaa
     4921 cctatcctgc cctgttgggc ttggaagagt ccattgcctt ttgtaaccaa accctggatc
     4981 aagctaatga aaaattagaa gaaattgccc agcagattcc ctttgaaaca gaatcgattg
     5041 taagtgtagt agaaagtttg agaatcaatg gctaaggaaa gagtggatgt actagcttat
     5101 aaacagggct tgtttgaaac gagagagcag gccaagcgag gtgtgatggc tggcctagtc
     5161 gtagcagtcc ttaatggaga acggtttgac aagccaggag agaaaattcc agatgacacc
     5221 gaattaaaac tcaaggggga gaaactcaag tatgtcagcc gtggtggttt gaaactggaa
     5281 aaggccttgc aggtctttga tttgtcggtg gatggcgcga ctacgattga tatcggggcc
     5341 tctactggag gttttaccga tgtcatgcta cagaatagtg ccaagttggt ctttgcagtc
     5401 gatgttggta ccaatcagtt ggcttggaaa ttacgccaag acccacgagt tgtcagtatg
     5461 gagcagttca atttccgcta tgctgaaaag actgatttcg agcaggagcc gagctttgcc
     5521 agtattgatg tgagtttcat ttcccttagt ctgattttgc cagccttgca ccgtgtcttg
     5581 gctgatcaag gtcaggtggt agcacttgtc aaacctcagt ttgaggcagg acgtgagcag
     5641 attgggaaaa atggaattat tcgagatgct aaggttcatc agaatgtcct tgaatctgta
     5701 acagctatgg cagtagaggt aggtttttca gtccttggct tggacttttc tcccatccaa
     5761 ggtggacatg gaaatattga atttttagcg tatttgaaaa aagaaaagtc agcaagcaat
     5821 cagattcttg ctgagattaa agaagcagta gagagggcgc atagtcaatt taaaaatgaa
     5881 taaaaaagag agacttgaaa aaattagaag attggtgaca gattatcaaa tcggcacgca
     5941 agaagaaatt gtagaacatt tgaaagaagc aggtatcact gccactcagg cgacggtatc
     6001 ccgagatatc aaagagttag gtattgtcaa aattcctttg agagacaaca cctatgtcta
     6061 cgaattgcca aaatcaatcg taaaaagtct gcaactggct gaagacaata tcgaatcggc
     6121 tgaattgatg gataagatga tcaatctcca agttattcca ggaaatacgg cttttgtaaa
     6181 agctcagtta atcgatactt ttgcagacaa gatttttagt tgtttgactg atgatagctc
     6241 gattttagtc attgccagaa gtggaagtct agcagaggaa atctttgaac aagtaaaaaa
     6301 ttggtaggtc tatatgttac ttgaaatttc gataaaaaac tttgccatta ttgaggctat
     6361 ttccctcaat tttgaaaagg ggatgactgt cctgactggt gaaacgggtg cagggaagtc
     6421 gattatcatt gatgccatga atatgatgtt gggagctcgt gcgacgacag atgttattcg
     6481 tcatggtgca ccaaaggcag agattgaggg gcttttctca gttgagaata gtcgtctttt
     6541 acaggaaatt tttgatgagc aaggtttaga gttaggtgat gaaattatca tccgtcggga
     6601 aatcttgcaa aatggtcgta gtatcagccg tgtaaatggt cagatggtta atctgtctgt
     6661 tttgcgagct attgggcaac atcttgtaga tattcatggt cagcatgacc atgaggagtt
     6721 aatgcgtccc caactgcata tccagatgtt ggatgaattt ggtgatgccg ctttttggga
     6781 cttgaaagaa acctatcaaa cgagttttga tgcctatcgg aaaatgcgca agcaggttct
     6841 ggaagtcaag aaaaaccaac aggaacacaa ggcacgtatc gaaatgttgg aatttcaaat
     6901 ggcagagatt gaggcagcaa acttgcaggc tggagaagac ttggatctca atcaagagcg
     6961 agataaactc ctcaaccaca aaaatattgc ggatacactg accaatgcct acagtatgtt
     7021 ggacaatgaa gatttttcaa gtctggccaa tgttcgttca gccatgaatg acatggaaag
     7081 tgtcgaagag tatgaccctg aataccgtga aatttcaagc tctctgtctg agacctacta
     7141 tgttttagaa gacattagca aacgtttgga agctatcatt gaggaccttg attttgatgg
     7201 caatcgcctc atgcaggttg agaatcgttt ggacctcctt catactatta ctcgtaagta
     7261 tggtgggact gttgatgatg ttttgcttta ttttgccaag attacggaag aatacaatct
     7321 cttgacaggc aataatcttt cgtctgagga catggaagca gagcttaaga agttggaagt
     7381 caatcttgtc aatttggcag gtcaacttgc ttctgctcgt cataatttgg ctcagcaact
     7441 cgaagctgag attaaacaag aactgcaaga tctttatatg gaaaaagccc agtttcaggt
     7501 tcgttttagt aagggaaaat tcagtcgtga gggaaatgaa atggttgagt tttatatttc
     7561 aaccaaccct ggagaagact ttaaaccctt ggttaaggtt gcttctggag gggaattatc
     7621 tcgtctcatg ttagccatta agtctgcctt ttcacgtaaa gaaggcaaga ctagcattgt
     7681 ctttgatgag gtggatacgg gagtttcagg tcgtgttgct caagctattg ctcagaaaat
     7741 tcataaaatt ggtcagtatg gtcaggtttt ggctatctcc catttgccac aagtaattgc
     7801 gattgcagat tatcaattct ttattgagaa gattagtaat gaccattcaa cggtttcgac
     7861 tgttcgtctc ttgacagtcg aagagcgagt ggaggaagtt gccaagatgt tggcaggtga
     7921 tgatgtgaca gaagcagccc tgacgcaagc cagagaattg ttgagaaaca gggagaaata
     7981 agatgacaga ttattatgta attggagatg ttcacggaaa agctgggatg ctggaagacc
     8041 ttcttaaaac ctgggatggt cagacccagt tgctctttct aggtgatttg attgacagag
     8101 gtgaggatag tcaccgtgtt cttgaaatgg tcaaggactt ggtggacaat caaggggcta
     8161 tctgtttgtc tggaaaccac gagtatatgt ttttgacttg gctagattac ccagaagaaa
     8221 gttatgacca ttatcgtcgc aatggtggag atacaaccat taactctatc ctaggtcgtc
     8281 ccttggatgc accagttgat ggagtagaag atgccaagcg ggttgccgct gaagcggcag
     8341 acttggtcga attcattcgt caaatgccat ttgtagtaga gacagacaag tatatctttg
     8401 ttcacgcagg tattgatttg accttggacg actggcatga aacaacagat tataaaaaag
     8461 tatggcttag aaaaccattc cacggagctg aaaatcatac tggaaaaacc attgtcttcg
     8521 gtcatacacc ggtctatggt ttgttacagc aagaacgcgg tacatctgag ctttggacta
     8581 cagaagatgg caagattgga atggatggag gagctgttta tggtggtgtc cttcacggga
     8641 ttgtctttac agaccaagga atgacagaac accactttat cgaaaatgac ggctttgtcg
     8701 ctgaagatta gtactcctag cagggtatgg tcttgtcaaa atatcaaaaa caatttataa
     8761 taaatagata ccctgaaagg aagagaatca tgaacttaga agaattgaaa aaacgacagg
     8821 agaagatccg taacttctct attatcgccc atattgacca cggaaaatca actctagcag
     8881 accgcatttt ggaaaaaaca gagacggttt caagtcgtga aatgcaggcc cagcttttgg
     8941 atagcatgga tctagagcgg gaacgtggaa ttactattaa gttgaatgcc atcgagttga
     9001 attacactgc aaaagatggg gaaacttata ttttccactt gattgacaca ccagggcacg
     9061 ttgactttac ctatgaagtt tcacgttcgc tagctgcctg tgagggtgct attttggtgg
     9121 tcgatgcggc tcaaggaatt gaggctcaaa ctcttgccaa cgtttatcta gctttggata
     9181 atgatttgga aatcatgcct atcattaata aaattgacct gccggctgca gatccggagc
     9241 gcgtgcgtac agagattgaa gatgtgattg gtttggatgc cagtgaagca gttttggctt
     9301 ctgccaaggc tggtattggg attgaagaaa tcctcgagca aattgtagaa aaagtaccag
     9361 caccaacggg tgatgtgacg gcgccactta aggccttgat tttcgactct gtttacgatg
     9421 cttaccgtgg ggttatccta caagtgcgtg tcatggacgg agtggtcaaa cctggtgata
     9481 agattcagct catgagcaat agtaagacct ttgatgtggc cgaagtcggt atttttacac
     9541 caaaagcggt tggtcgtgat ttccttgcga ctggtgatgt tggttacatt gcggcgtcta
     9601 tcaagacggt tcaggatact cgtgtgggtg ataccgttac cttggcaacc aatcctgcgg
     9661 cagaaccatt acatggttat aagcagatga atcctatggt ctttgcgggt ctctacccaa
     9721 tcgaatcaaa caagtacaat gacctgcgtg aagcgcttga aaaattgcaa ctgaatgatg
     9781 ctagtcttca gtttgaacca gaaacatctc aggcacttgg atttggtttc cgttgtggat
     9841 ttcttggact tctccatatg gatgttatcc aggaacgttt agagcgtgag ttcaatattg
     9901 acctcatcat gacagctccg tctgttattt acaaagttaa tttgaccgac ggtgagtcta
     9961 tggatgtgtc taacccatct gagtttccag acccaactaa gattgcgacc attgaagagc
    10021 cttatgtcaa ggcgcaaatc atggtaccac aggagttcgt cggagcagta atggagctag
    10081 ctcagcgtaa gcgtggggac tttgtgacta tggactatat tgatgataac cgtgtcaatg
    10141 ttatctatca aattcctctt gctgaaattg tctttgactt ctttgataaa cttaagtctt
    10201 caacacgtgg ttatgcaagc tttgactacg aattgtcaga atatcgccca tctaagctgg
    10261 tgaaaatgga tatccttctc aatggagata aggtggatgc tctcagcttt atcgttcaca
    10321 aggactttgc ctacgaacgt gggaaactca tcgttgataa actcaagaaa atcatccctc
    10381 gccaacaatt tgaagttcca atccaagcgg ctattggaca caagattgtc gctcgtactg
    10441 atatcaaggc ccttcgtaag aacgtacttg ctaaatgtta tggtggtgac gtttctcgta
    10501 agcgtaaact ccttgaaaaa caaaaagctg gtaagaaacg catgaaatcc atcggatcag
    10561 ttgaagttcc gcaagaagcc ttcctcagcg tcttgagtat ggatgaagaa taagttatca
    10621 gaaatgcctt tccttgttca caggaaattt atataagaat caatagtaaa gcaggcttag
    10681 atggtctgct tttttagttt ttatactctt cgaaaatctc ttcaaaccac gtcatcgtcg
    10741 ccttaccgta
//
LOCUS       DAVHSH010000061        10746 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000061 DAVHSH010000000
VERSION     DAVHSH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.062"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..72
                     /locus_tag="VVR08_001783"
     CDS             <1..72
                     /locus_tag="VVR08_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6075642.1"
                     /translation="NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(122..544)
                     /gene="nusB"
                     /locus_tag="VVR08_001784"
     CDS             complement(122..544)
                     /gene="nusB"
                     /locus_tag="VVR08_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU6075643.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(537..926)
                     /locus_tag="VVR08_001785"
     CDS             complement(537..926)
                     /locus_tag="VVR08_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6075644.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(948..1508)
                     /gene="efp"
                     /locus_tag="VVR08_001786"
     CDS             complement(948..1508)
                     /gene="efp"
                     /locus_tag="VVR08_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU6075645.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(1637..3079)
                     /gene="gatB"
                     /locus_tag="VVR08_001787"
     CDS             complement(1637..3079)
                     /gene="gatB"
                     /locus_tag="VVR08_001787"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU6075646.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LDGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVVDFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3079..4545)
                     /gene="gatA"
                     /locus_tag="VVR08_001788"
     CDS             complement(3079..4545)
                     /gene="gatA"
                     /locus_tag="VVR08_001788"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU6075647.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(4545..4847)
                     /gene="gatC"
                     /locus_tag="VVR08_001789"
     CDS             complement(4545..4847)
                     /gene="gatC"
                     /locus_tag="VVR08_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU6075648.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPKKDNYYIKVPAILDDGGDA"
     gene            5060..6604
                     /locus_tag="VVR08_001790"
     CDS             5060..6604
                     /locus_tag="VVR08_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU6075649.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            6859..7057
                     /locus_tag="VVR08_001791"
                     /pseudo
     CDS             6859..7057
                     /locus_tag="VVR08_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            7320..7508
                     /locus_tag="VVR08_001792"
     CDS             7320..7508
                     /locus_tag="VVR08_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU6075650.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            7665..8030
                     /locus_tag="VVR08_001793"
     CDS             7665..8030
                     /locus_tag="VVR08_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6075651.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            8033..9700
                     /locus_tag="VVR08_001794"
     CDS             8033..9700
                     /locus_tag="VVR08_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU6075652.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(9744..>10746)
                     /locus_tag="VVR08_001795"
     CDS             complement(9744..>10746)
                     /locus_tag="VVR08_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6075653.1"
                     /translation="SKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLAI
                     STSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQ
                     AVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMS
                     RFRVQIMNQFERKSHEYKTIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKIL
                     SYSEDLKHHYQIYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIV
                     NALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         3126 a         2037 c         2462 g         3121 t
ORIGIN      
        1 aactttctca atcatgcaaa acctatctgg atttttgttt acaattatat ctattatcat
       61 ttttttagat agtgggaggc aaagaaaaaa gtgtttgata tctatcaaac actttttctt
      121 tttattgttc ttctgttaca aactggctga gcagtccatt gataaaacgg gcagattttt
      181 gatcggagaa gtcctttgca agctcgatag cttcattaac agcaaccagc tgaggagtgt
      241 caaatgaagt gatttcaaag actcccaagc gaaggaggtt tctctccacg agcgttaagc
      301 gttcaatggt ccaacctgct tttaaatgct gagtgatttg cttatctagt tcttcctttt
      361 tagcttgaac accagaaacg aggtctatca aaaaggctgg aagttgtaca tccgtatctt
      421 cacgatcatg agtataggcg aaacgacaag cagtttcgac atccgtaccg aactcaaggc
      481 tcatgagagc ttgaaaagcg catttacgga gttggcgtct agattctaat agtggactag
      541 tcattgagga agtcctcgtc aaatagatct ttcaattctg gttttggtgt tttatctggg
      601 acgatacctg caacgtgaat attgatagca gcgagttcta catcagccat attacggacg
      661 gcatctttga cagctttctg gatagcaacc gctaccttag gaacttttac tccgtactca
      721 aggtagagat agatatctgc tgtgagttct tcgtccacgt ttttaagata aatgccacgg
      781 ccgagtgaaa gttttgaaag ggtatcagac actgatctgt ttgaaaaaga gtgaacaccc
      841 tctacctttg cagtagcgat agcaatgatt ttttcaagta cacgtggggc gataacgatt
      901 tcgccaagtt gttcttcaat tcccatagaa tgacctcttt ctagagatta ggcacgagaa
      961 acgtaagttc cttctgcagt gttgataacg agtttttgtc ctgcttcgat gaagtctgga
     1021 acgtttacga caagtccagt ttccatcgtt gctggtttac cagaacctgt aacagtagca
     1081 cctttgatag atggttgagt ttcagcaact gtcaactcaa cagtagtagg aacggtgaca
     1141 ccgatcactt cagttccgta gaattggatt ttcacatcag agttttcaag gatgtaaagc
     1201 aattcgtttt caacattgac tacagggatt tcgtattggt cgtaagtttc tgtattcatg
     1261 aagtatgctg tgtcatccat tttgtacaag tattgagctg ggacagtctc gataatagct
     1321 tgttcaaatt tttcctctgg acggtagctt gtgtcaaatg tagaaccagt acggacatca
     1381 cgcaatttca tacgcatgat cgtgtttcct ttacctggtt tgtggtgact agcttccaaa
     1441 acgcgaatca atttgccgtc agctgtttca aaggtcatac cagcttttaa tttacttgct
     1501 tcaatcatgt ttttacctct ttaataaata ttattactct tcattttacc ataaaatact
     1561 ctggaaataa agccaaaata gttattggga gttggtagag aagaaaaaac caaccttagg
     1621 gctggttttg ttctgtctag ttttctttca acttcgccaa ttcctgtgca agtagtttaa
     1681 gggcaacttg tgggttggct tggcctttgg ttgccttcat aaggaatcct gtaaaggcct
     1741 tgtcggcgtt acgtttgcct gacttgaagt cgacaacagc agcttcgtta tcggcaaaga
     1801 cttggtggat gattgggatc aagatagctg gatctgaaat ttgaaccata cctgcttttt
     1861 ccacgtattc acgcgcgcca ccgccatttt tagctagatg gacaaagact ttcttggcaa
     1921 tcttagatga aatagtaccg tcttcgatga tggcaatcat ttcaaccaag ttttctggtg
     1981 tcaattcgat ttgttccagt gttttacctt cagcattcaa gaactgagcg acttcccctt
     2041 ggagccagtt agagacttgt ttggcatcac catctagggc aacagctttt tcaaagaaat
     2101 cagaagtgac tttattagca gtcaactgac tagcatcgta gtctgataaa ccaaggtcag
     2161 atacataacg cgcacgacgt tcttttggaa actctggcaa ctcagtccgc atttcctcaa
     2221 tccactcgtc agaaatttca aagaggggta ggtctggttc tgggaagtag cggtagtctg
     2281 cagccccttc cttgacacgc atgagaatgg ttgctttatt cgcttcatcg taacggcgtg
     2341 tttcttggcg gatttgacca cctgagcgaa gaatttcagc ctggcgttgg acttcgtatt
     2401 caagaccttt acgaacgttt gagaaggagt tgaggttctt caattcagtc ttggtaccga
     2461 atttttcttg accataaggg cgaagggaga tgttggcatc cacacgcata gaaccttctt
     2521 ccatcttaac gtcagaaatg ccagcgtact ggataacttc cttgagggct gtcagataag
     2581 cataggcttc ttcaggagaa cgcatatctg cctcagatac aatctcaatc aagggaaccc
     2641 cttggcggtt gaggtcaaca taagagtagc cgtctgtacc atgggtgttt ttaccagcgt
     2701 cttcctctag gtgggcacgt tcgataccga ttttcttggt cgtaccgtct tctagttcga
     2761 cttcaatcca gccattatat ccgattggtt catcaaattg agaaatttgg taggctttgg
     2821 ggttatcagg atagaagtag ttcttgcggt caaagtgcat ctttttgtgg atgtccatgt
     2881 tgagggcaag agcagccttg attccggcat cgacaacccc tttattgaga actggcagaa
     2941 ctcctgggaa agaccagtca atcacgttag tgttggcatt ttgatcattt ccgaagtggg
     3001 cagaagtagg tgagaagatt tttgaattgg tgttgagctc tacgtggact tcaagtccga
     3061 tgactgtttc aaagttcatt agttgtcacc tccaaaaatc acgggttgtt gtttgtggta
     3121 gtctgttgtt gcttcaaaag cagcagcagc ttggtaaatg gtttcctcag agtacttggg
     3181 accaatcaat tgcagaccga caggtagacc ttgagagaat ccagcaggaa tcgaaattcc
     3241 agggagacct gctaagttta caggtatggt caagaggtca gccaagtaca tggcaactgg
     3301 gtcatggttg agtgagtcca agtcataggc aacacttgga gcagttggac ccaaaatcaa
     3361 atcgtaatcc gcgaagactt tttcgaaatc ttgaatgatg agggtacgga cttgaccagc
     3421 ctttttgtag taggcatcat agtaacctga tgaaagactg aaagtaccca gcatgatacg
     3481 acgttttacc tcttcaccaa aaccttggct tcggctgttt acatagattt catcaaggtt
     3541 ggttgcatct tctgcgcgat agccgtaacg gataccgtcg aagcgttgca agtttgatga
     3601 agcttctgat gaagcgatga tgtagtatac ggcaactccg tatttagagt gaggaaggct
     3661 gacttcttcg acaatagcac ccaatttttc aaagtgttta gcggcattta gaatggtttc
     3721 cttaacctct gggttaattc cttcaccgag gtattcctta ggcaaagcga ttttcatacc
     3781 cttgatgtct tggccgattt ttgaagtaaa gtcggcgatg cggacaggag cagaagtaga
     3841 gtctttagca tcttcgctgg caatagcgtt gagcaagagg gcattttcct taacagtagg
     3901 agcaaaaggt ccaatctggt ctaatgagct accaaaggca atgagaccga aacgtgaaac
     3961 tgttccgtag gttggtttga gaccaacgat tccgttgaag gcagcaggtt ggcggatgga
     4021 accaccagta tcagaaccaa gtgacaagcg aacttgtcct gaggctacag ctgcggcaga
     4081 accacttgat gacccaccag gaaccttgct gtggtcccaa gcgtttttag ttgctccgta
     4141 gtgtgaagtt tcacctgaac cacccatagc aaattcgtcc atgttggtct ttccaacgac
     4201 aatcatgccc ttggtttttg cattggcaac agctgtcgca tcaaagattg gctcatagtt
     4261 gtagagcatt tttgaggcag cagttgtgag aataccgtct gtagagatgt tatccttaac
     4321 agcaagtgga attcctgaaa ggacattgtc agcatcaatt ccagcttcat caatggcttt
     4381 agcttgaaca agagcttgct cctcagcgat ggtgacaaat gaattgaggg cttcctcacg
     4441 agacttgata ttttcaagtg ttgcttgggt caattctgtt gcagaaattt ccttagagac
     4501 aaggagattg tgcaactctt caatagtttt attgttaaaa gtcattaggc atctcctcca
     4561 tcgtctagga tagctggcac cttgatatag tagttgtctt ttttaggtac gtttttaaac
     4621 aagcgatcac ggtctgttcc ttcttcggcc acatcagggc ggagtacagt cttgcggtca
     4681 gccatagtcg tagtaggtgc gacaccagtt gtgtcaactt cgcccagcaa ttcaaccatg
     4741 tcaacaatct tagacaaggt ggtcgcaaag gcagcagttt ctttttcaga gaatcttaat
     4801 tttgaaagat tggcaacgtg tgttacctct tcttgcgtaa ttttcatctt gcatcctttc
     4861 gtgaaatgat gatttttagt ctgttctatt ttaccatatt ttcctataaa taagggaggg
     4921 ggaagtgaaa agaaatagaa attgaaaaaa atgctaaaat ccgatataat ggagtgttga
     4981 aaggaatggt aaaatccaat gtaaaaatca ttctcagcta ttgaaacaag aaaaatagag
     5041 aatcaaagaa agagaactta tgaatattca agaagaaatt aagaaacgtc gtacctttgc
     5101 cattatctcc cacccggacg cggggaaaac aaccatcact gagcagttac tctactttgg
     5161 gggtgagatt cgtgaggctg gtacggtaaa agggaagaaa acagggactt ttgctaaatc
     5221 tgactggatg gatatcgaga agcaacgtgg gatttctgtt acttcatctg ttatgcaatt
     5281 tgactacgac ggcaagcgcg tgaatatctt agacacgcca gggcacgagg acttctcaga
     5341 agatacctat cgtaccttga tggcggtgga tgctgcggtc atggtcgtgg actctgccaa
     5401 ggggatcgag gctcaaacca agaaattgtt tgaggttgtg aaacatcgtg gcattccagt
     5461 ctttaccttt atgaacaagc tggaccgtga cggtcgtgag cctttggatc tcttgcaaga
     5521 attggaagaa atcttgggca ttgctagcta ccctatgaac tggcctatcg ggatggggaa
     5581 agcctttgag ggcttgtatg acctctataa ccaacgttta gagctttaca aaggggatga
     5641 gcgttttgcc agtctagaag acggggacaa actctttggt agcaatcctt tctacgagca
     5701 agtcaaggat gacattgagc ttttaaatga agccgggaat gagttttcag aggaagctat
     5761 tctggctgga gaattgacgc ctgtcttttt cggttcagcc ctgacaaact ttggtgtgca
     5821 gaccttcctt gaaaccttcc tcaagtttgc tccagaacca catggtcaca agaaaacaga
     5881 cggtgaaatt gtggatcctt atgacaagga tttctcagga tttgtcttta aaatccaagc
     5941 caacatggac cctcgtcacc gtgaccgtat tgcctttgtc cgtatcgtat ctggcgaatt
     6001 tgagcgcggc atgagtgtca atctccctcg tactggtaag ggggctaaac tgtctaatgt
     6061 tactcagttt atggcggaaa gtcgtgagaa tgtgatcaat gccgtggcag gtgatattat
     6121 cggggtttac gataccggta cttatcaagt tggggatacc ttgacagttg gtaaaaacaa
     6181 gtttgaattt gaaccactgc caacctttac tcctgaaatt ttcatgaaag tttctgctaa
     6241 gaatgttatg aagcaaaaat ccttccacaa ggggattgag caattggtgc aagaaggtgc
     6301 tattcagctt tataagaatt accaaacagg tgagtacatg ctaggcgctg taggtcaact
     6361 ccagtttgaa gtctttaaac accgcatgga aggtgagtac aatgcagaag tagttatgaa
     6421 cccaatgggt aaaaagaccg ttcgttggat caagcctgag gacttggatg aacggatgtc
     6481 gtcaagtcgc aatatcttag ccaaagaccg ttttgaccaa ccagtctttc tctttgaaaa
     6541 tgactttgcc ctccgctggt ttgcggacaa gtatccagac gtagagttag aggagaagat
     6601 gtgactcagt accaacaatt ggaactaaag ttccaaattg ttggacgcta gtcgctattt
     6661 ggcgaactag ctaactgcct tactaactac gtttggcaaa tgaaatcgat ttgtaaaact
     6721 ccgtgtcgta atgtaaaaat tgtaaaccgt aatgggactt catctaaaat ctccactggt
     6781 atggttttac gaacgaatgg gcgaaaataa tggttacgta gaaacatatg atgggaataa
     6841 aaagaaatga gataaagagt ggaagaagag aaaaaagcga ttgtcttagg tgcagataat
     6901 gcttatatgg ataaagttga aataacaata aaatctcttt gtgttcatct attataatct
     6961 taagttttat gtttttaatg atgaccttcc gcgagaatgg ttccaattga tggaaaaaag
     7021 actagagact ttgaatagtg agattgtgaa tgtttagatt gacagtagta ttctgaaagg
     7081 ttatcgtctc ccctttgagg gactttcata tgatgatttt tatacacata attttaattc
     7141 tggtgttctg ttaatcaaca atggcatgtg gagagcagaa aatgtcacgc aagacctgat
     7201 ttaagacaca aataaaaaat cttccaattc ccttgcaaaa aacaagaaag tgtgataaca
     7261 tagtacggta tgtggtgcta gcacatccgc tatattagat ctaataggag gaaaacacaa
     7321 tggctaaagt atgttacttt acaggtcgta agactgtatc aggaaacaac cgttcacacg
     7381 cgatgaacca aacaaaacgt gccgtaaaac caaaccttca aaaagttact gttcttatcg
     7441 atggtaaacc taaaaaagtt tgggcttcag ctcgtgcttt gaaatcaggt aaagttgaac
     7501 gcgtttaata ataaaagcaa aggagacctt agggtctttt ttcttttatt gtgggtataa
     7561 catcgtttga aaaatagagt aaatatccgc tgatacatca ttctgctttt acacttgggc
     7621 tgaaatatga taaaatagag tatcaactag ttgaggtaaa aaggatgact gtaaaaatta
     7681 atacaaaaga tggtcaaatc gaactaacag atgaagtgat tgcaaccgtc gtaggtggag
     7741 cagcaactga gatttttggt gtggtcggta tggctagtaa aaatgccctc aaagataatt
     7801 tccaagccct gctaggtaag gaaaattatt ctaaaggtgt cgtcgtaaag gcagccgaag
     7861 atggcagtat tgcagttgat gtatataccg tgttaagcta cggaacaaag attagtgaag
     7921 tgtcaaaaaa cattcaagag cgtgttgcct ttagcttgga aaaccagctt ggaattactg
     7981 ctcagactgt aaatgtctac attcaaaata tcaaagttgt aggagaataa ccgtgtcaaa
     8041 aattactact agcttatttc aagaaatggt gcaggctgca tcaactcgct tgaataagca
     8101 agctgaatat gtcaattcat taaacgtctt tccagttcca gatggagata ctgggacaaa
     8161 tatgggaatg accattgaaa atggtgctaa agaagttgca gacaagccag cttctacagt
     8221 tggagaagta gcgagcattc ttgccaaagg gcttttgatg ggtgcgcgtg ggaactcagg
     8281 agtgattaca tctcagcttt tccgtggatt ttcccaagct atcaaggata aagacgagtt
     8341 aacaggtcaa gacttggctc tggccttcca atcaggtgtg gaagttgcct ataaggcagt
     8401 gatgaaacct gttgaaggaa cgattttgac agtttctcgt ggagctgcta tcggtgctaa
     8461 gaaaaaagct gagcaaacag atgacactgt tgaagtcatg cgcgcagcct tggaaggtgc
     8521 taaaacagct ctagctaaaa caccagacat gcttccagta ttgaaagaag ttggcgttgt
     8581 ggactcaggt ggtcaaggat tggtcttcat ctacgaaggt ttcctttcag cccttactgg
     8641 cgaatatatt gcatctgagg actttgtagc gactcctgct aacatgagtg agatgatcaa
     8701 tgtagagcat cataagtctg tagctggtca cgtagcgact gaggacatca cgtttggtta
     8761 ctgtactgaa atcatggtag ctcttaagca aggtccaact tatgctaaag attttgacta
     8821 cgatgaattc cgtaactact tggatgagct tggggattct ctcctcgttg ttaacgatga
     8881 tgaaattgtc aaagtccatg ttcatacaga agatccagga cttgttatgc aagaaggtct
     8941 caaatatggt agcttggtca aggtaaaagt tgacaatatg cgtaaccaac acgaagcaca
     9001 ggttgagaaa gaagctactc aagttatcaa gtcggctgaa gaaaaagagt atgctttgat
     9061 tgctgtggtg gctggtaaag gtctagcaga tatcttctgt tctcaaggcg tggattatgt
     9121 tatcgaaggc ggtcaaacca tgaacccttc aacagaagac tttatcaagg ctgttgaaca
     9181 ggtcaatgcc cgtaacatca tcttcttgcc aaacaacaag aacatcttca tggcagctca
     9241 atctgcggca gaagttttgg agcaaccagc agtagtggta gaggctcgca ctcttcctca
     9301 aggtatgaca agtcttcttg cctttgatcc aagcaagtcc attgaagaaa atcaagagcg
     9361 tatgacagct gctcttagcg atgtcgttag cggaagcgtc acaacagccg tgcgtgatac
     9421 aacgatcgat ggcttagaaa tccatgaaaa cgataatcta ggtatggtgg atggaaaaat
     9481 tcttgtgtca aaccctgata tgcaccaaac attgactgaa accttgaaac atatgttgga
     9541 tgaagacagt gaaatcgtaa ccttctatgt cggtgaagac ggaagcgaag aacttgccaa
     9601 tgaaatcgct caagaaatcg tagaagaatt cgaagacgtt gaagtcgaga ttcaccaagg
     9661 tcaacaacct gtttacccat acctatttag tgtggaataa gattaatggg ctctttgtca
     9721 actgtagtgg gttgaaaaaa aagctaagct cgagaaagga caaatttcgt tctttctttt
     9781 ttgatattca gggcgataaa aatccgtttt ttgaagtttt caaagttccg aaaaccaaag
     9841 gcattgcgct tgataagttt gatgagatta ttggtcgctt ccaatttggc gttagaatag
     9901 tgtagttgaa gggcgttgac gattttctct ttgtccttta gaaaggtttt aaagacagtc
     9961 tgaaaaagag gatgaacctg cttaagattg tcctcaatga gtccgaaaaa tttctccggt
    10021 tccttattct gaaagtgaaa aagtaagagt tgatagatct gatagtggtg tttcaagtct
    10081 tctgaatagc ttaaaatctt gtcaagaatt tctttatttg ttaagtgcat gcgaaaagta
    10141 gggcgataaa aacgtttatc gctcaattta cgactatcct gttggatgag tttccagtaa
    10201 cgtttgatag tcttgtattc atgagatttt cgttcaaact gattcataat ttgaacacga
    10261 aaacgactca tggcacggct gagatgttgg ataatatgga aacgatctag aacgatttta
    10321 gcacacggaa aaagctgttt agccaagtca tagtaaggac taaacatatc catcgtaatg
    10381 attttcactt gacaacgaac ggctctatcg tagcgaagaa agtgatttcg gatgacagct
    10441 tgtgttctgc cttcaagaac agtgataata ttaagattat caaaatcttg cgcaatgaaa
    10501 ctcatctttc ccttagtgaa ggcatactca tcccaagaca taatctttgg aagccgagaa
    10561 aaatcatgct caaagtgaaa gtcattgagc ttgcgaatga cagttgaagt tgaaatggcc
    10621 agctgatggg caatatcagt catagaaatt ttttcaatta acttttgagc aattttttgg
    10681 ttgatgatac gaggaatttg gtgatttttc tttaccaggg gagtctcagc aaccatcatt
    10741 tttgaa
//
LOCUS       DAVHSH010000062        10725 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000062 DAVHSH010000000
VERSION     DAVHSH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.063"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(87..1511)
                     /locus_tag="VVR08_001796"
     CDS             complement(87..1511)
                     /locus_tag="VVR08_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6075654.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2056..4335)
                     /gene="pulA"
                     /locus_tag="VVR08_001797"
     CDS             complement(2056..4335)
                     /gene="pulA"
                     /locus_tag="VVR08_001797"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU6075655.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4447..6405)
                     /gene="ligA"
                     /locus_tag="VVR08_001798"
     CDS             complement(4447..6405)
                     /gene="ligA"
                     /locus_tag="VVR08_001798"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU6075656.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6498..7676)
                     /locus_tag="VVR08_001799"
     CDS             complement(6498..7676)
                     /locus_tag="VVR08_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6075657.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7756..8619)
                     /locus_tag="VVR08_001800"
     CDS             complement(7756..8619)
                     /locus_tag="VVR08_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6075658.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8622..10523)
                     /locus_tag="VVR08_001801"
     CDS             complement(8622..10523)
                     /locus_tag="VVR08_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6075659.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3218 a         2358 c         1918 g         3231 t
ORIGIN      
        1 accaaaaagt tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca
       61 ggaaaacaat ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt
      121 gtcatcgctt caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca
      181 aggaatggga aattatctgg accacgctgg gttttattat taatgtggac tgtacctact
      241 tcaagttttt cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga
      301 aggccgaatt cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg
      361 attggtaaaa caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg
      421 tcaaaaagca ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc
      481 tctttttctt gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata
      541 acaggtgtaa tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc
      601 tgaagcaaag tagctaattt atctgctaca ctttcgagaa caatgacacg tttaatggcc
      661 gtgcaacgtt gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc
      721 aaatctgcat cttctagtac aagagctgca tctttcccac caagttccaa catgatagga
      781 cgcataccag ctaaacgacc aatacgttct ccaatagggg ttgaacctgt aaagttgatg
      841 aagttgactt ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg
      901 gtgttgaaaa cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca
      961 gaaatggaac cttgtgttgg tggcttaaac atgaccacat tccctgcaat caaggcaggt
     1021 gcaattttag aagcagataa attaactgga taattaaagg gagcaatcgc tagcacgata
     1081 ccaactggtt cacgacggac aacagccagt ttgtttttac ttgctgcctc aaaaccacca
     1141 ccttccattg cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct
     1201 gctgtacgca ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg
     1261 atagtaccaa ttttttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc
     1321 gcacgttcaa ttgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata
     1381 gcctcatcag cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt
     1441 ggtgaataaa tcgtaatttc ttgttcagat gatttccatt ttccatttac taaattctga
     1501 tatcttgtca aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag
     1561 aaaatcacaa ccctttttgc aaaatttttg agattatttt cacaagcttg atttttcaaa
     1621 gtatactcaa taaaaataaa aaaaatccac tacatcaagg cgagactaat gtggtttgaa
     1681 gaaattttcg aagagcgtga atgagtatca tctatagtaa aataaaaaaa ctgaacaatt
     1741 tggttgggga cagtcaaacc aatttctcac aatgttttag aaacaagggt gtgctattcc
     1801 aatttcaggc tactataact gtcatagatt gctgaaacaa agtctaggta aaaatcttca
     1861 taataaaaag accccctatc aagtgttcaa aaactttgat aggaggtctt gttttgtgaa
     1921 aatatttatc aaattttcta tacaagtgag ctgttagcca ggttctttct attctttcaa
     1981 tttcaatgaa tggatttttt accaatactc ataactggga atttgtctgt gtaaaaatag
     2041 cgagatagat ggtatttata aaacactcaa gacagctaga ctaatatcat ttaaaacatt
     2101 atcttctttt gagcgactgt tggttaccaa catagctaaa tttcctgcat tttcaaattg
     2161 atagggttct gatttagcat tcacaactac caagaggtgt tctttgccgt gaacttcata
     2221 gataaggcag ccgctatgtt caatcgcaga atgcacaaag acatgatggt aaatttcatc
     2281 atagctagag taagaaaagg caccagtttt tgtcttcaat cggatgactt gacggataaa
     2341 ctcaatactg tcttgacgct cattaatcaa gttccagttc acttggttca cactgtcagg
     2401 agcattatag ctattcatcg cacgctctct atcatcatgg gtcaactcac cattttcacc
     2461 agtcgcaacc agtttggtac gaccaaattc ttgaccgatt tccataaagg ccatcccctg
     2521 catgagcaga ttcatggctg tggcagtttc gaccttgcgc atgatttgct ctgaactttg
     2581 gtctggatga agggttgcca ataaatcgtg aagattgtaa ttgtcatggg cttctacata
     2641 gttaagcacc tgatttggat gtgtataggt tcctaattca cgacttccta ggattgcttt
     2701 agctagaatt ggctctgtcg cagcaccact gacaaaacct gacttgatag caccataaac
     2761 ttctccccct ttgacagcat cgcgctgatt gtcattaaag aaaccaatat ttggcatctg
     2821 gtaggcattg tccttcttgg ccttatcata aggggtaaga cctgttccca tatcccatcc
     2881 ttctccatag aggataatgt tggagtcgat ttcatccaag ctttgacgaa tcatctgcat
     2941 ggtcttgaca tcatgaatcc ccatcaagtc aaaacggaag ccgtcaatat tatattcctg
     3001 cacccagtat agaagagaat caatcatata cttgcgaaac atttcgtgtt cactggctgt
     3061 ttcatttcca acacccgttc cattctggaa ggtaccatct ggattcatac gataatagta
     3121 atcagggact gttgtttgga atggtgcatc aacaactgag aaggtatggt tatagactac
     3181 atccataatg actccaatac ccgcatcgtg ataagcttga accatcacct tcaaatcacg
     3241 aatgacctga gctggatcat ctggattagt tgaaaaacta gtttctggcg cgttatagtt
     3301 ttgtggatca taaccccagt tgtaggttac atttccatcc tcatcgtatt ctttatgacg
     3361 gtctgcaatt ggttgcaatt gaacataatt gtagcccagc ttcttgatgt aatcaaaagc
     3421 agttgactgg ccgtattggt taactgttcc agcctgagca gcacccaaga aagttcctcg
     3481 aagatgttca tctacacccg atgtaggtga tttagtcaaa tcacgaatgt gcatttcaca
     3541 gataactgcc ttacatggat tttccaagcg ccaagtagcc tccgaaccgt gcttaacctc
     3601 gaagttttca acttgctttt ctacatggct cagaatagct gaacgtttgc catcagggct
     3661 ggtcgcgatt gtataaggat cacgtgtcag tgtttggtga tgagggaatt ggacttgata
     3721 ctgataagtc ttacctacca aatcttcttc aacatccaaa ctccagacac cgattgtatt
     3781 gtccttatga ttataagagt agctattgcc tcttttcatc tcaaaagtct tccaaacggg
     3841 tgcatcatta gcagctgatt cataaacgac aacttgcact tctgtcgctg taggtgacca
     3901 gagggaaaaa tgagcctgat tgtcctctac acggcaaccc aattctcctt ggtaacccca
     3961 atgatgatca aaactagcac tgttaatggc cttatcaaag gcaaaaggat tttgattttt
     4021 atagaaagga ctggcaatag caggattttc agagtaataa atcctatcat cgccttccaa
     4081 aatccagacc tctgtcaata ggggatagtg attaaaacgg atagaatatt ctttactagt
     4141 ttgacctgta tgaaccacaa aattcaagct ttctataaca tgtgaacttg ggtgttcaaa
     4201 gctaaataaa gctccaaaat aatcttcttt gtaggttagc aaatcaattc gttgatcctg
     4261 actttttaca aaggagcaag tgtcatattc tccattctta cgatggtaat gaatgcgcat
     4321 agggtagtta tacatttttt atttttcctt tttactttgt ttctatttca ctaataaatt
     4381 tttgtcaatc tcgtctcaat taacagacat agtcatattc tctaaactct gtttttaaac
     4441 gatccattac aaactttcta gccatgcctc atctctgacc tggataccaa gttcttgtgc
     4501 tttttgcagt ttacttccag cgtctgcacc taccacgacg aggtcggtct ttttagaaac
     4561 actacctgtc actttggcac ccagactttc gagtttactt ttagcttctg agcgcttgag
     4621 tcgttccaat tttcctgtca ataccacggt caaacctgac aaggccgcat ccgctactac
     4681 cgtctgtcct ttatagtcca gattgacccc agtttctttc aattctctga gcagaatttc
     4741 agagccttct gtcgcaaaat aagtctgaag acttttggca atcacgccac ctagactttc
     4801 aatactagcc acttcctctg aatctgcctg atacagattt tcaattgaat ggaaatattg
     4861 aagtaaaagc tgactagcct tgcttccgac atgacgaatt cccaaaccaa ataagagctt
     4921 ctcggcagaa ttttcctttg atgcttggat agcctgatac agtttagcag cggacttttc
     4981 cttaaccccc tctaaaagga ggaaatcctc ttcttgcaaa cgataaatat ccgccacatc
     5041 cttgactaaa ttagcagcaa aaagcttctc aacaatagat ggaccaaggc ctgtaatatt
     5101 catagcatca cgagaagcaa agtgaatcaa gccttccatg atttgagcag ggcaacgcgg
     5161 attgatacaa cgtagggcca cttcatcttc aaagtgcaac aagtcagagt tacaacttgg
     5221 acagtttgta gggatatcta gtttttcttc agaaacccgt ttggactcta ccacacgtaa
     5281 aacggcaggg atgatgtcac cagccttata tacaatgacc gtatcgtctt ttcggatatc
     5341 tttttcagca atataatcta cattgtgcag ggtcgcacgg ctaacagtcg taccggcaag
     5401 ttgtactggt gttagattag cagttggagt tacaacaccg gtacggccaa ctgtccagtc
     5461 aactgataag agttgagctt ctttttcttc agcagggaac ttgtaggcta ctgcccactt
     5521 tggagcctta acggtaaaac caagttcttc ttgacttgct aggtcgttga ccttgattac
     5581 cactccatca atatcgtaag gcagattttc ccgttcctgt cctacttctt ggataaaatt
     5641 ccagatttca tctatgtttt cagccaagat tcgcttagga ttgaccacaa aacctagttg
     5701 ttctaggtac ttcaaaccct tttcttggct atcacgagtt gaagggctgg cttcttgata
     5761 gagaaacgtt gcaagattac gcttggcaac tactgctgta tccaactgac gcagagttcc
     5821 tgctgccgca ttacgaggat tagcaaattc aggctctcca ttttcttggc gcacttggtt
     5881 aacttggtca aaggaagcgc gtggcatgta acattcccca cgaactgtga tatctagttc
     5941 ttctggcaaa gtcaaaggga tgtccttaac acgcttgagg ttttctgtga tattttcacc
     6001 aattgaacca tctccacgtg ttaccccagc aaccaaaatc cccttttcat aagtcagcga
     6061 gatagataag ccatcgattt tcagctcaca aatataggtc ggatgagcca cttccttacg
     6121 aacacgcgca tcaaaagcat ctagctcctc acgtgaaaaa gcatcctgca aactataaag
     6181 aggatactga tgactgtatt tttcaaaacc atctaaaacc ttgccaccaa cacgatgagt
     6241 cggactgtct gctagcactt gctctggata agcagtttct aactcgacca actcacggta
     6301 aaggcggtca tactcactgt ctgaaaccga gggattatcg ctggtatagt actcagtcgc
     6361 atagcgattg agcaaagcga ctaactcatt cattctttta ttcataagac cattttacca
     6421 taaaacaagc cctcctcaca aacgagaagg acggaaaaaa cacttagttt gaaattattt
     6481 ttgaaactca agcaacctta tatcaatttt tcaaaatgag ttcgaacata aataaacgat
     6541 atacaagaca agatgataac accacttcca attatcagga aagaagagag atgtacactt
     6601 ggcaagactg tcataaatcc ttttgcaata ggcataaata gaatagctaa ggtaaaaatt
     6661 gtactcagta ctctcccaag aaattcgctc tcaaccttgg tttgtacttg agtaaaaaag
     6721 tgaatattaa aaatcgtcat aaacaattca caaactaaat ttccagaaaa ggaaagaaaa
     6781 gttggaagtg gtaatcccat cataaaaact ccgacacctg tcaaagccag taaaatcaaa
     6841 agattataaa tattagcttt aattttacta gctagaagag ccccaatgat ggaaccaata
     6901 gcccccatag ttaaaatact tgcataggct ccttctgatc cgtaaagctg attcgaaaag
     6961 ggaagtagaa attcaaaagc tgcaaaaaag aaattaacgc tggaagctac cagcaaaagg
     7021 aagaaaattt cttgctgatg ccagatatag tgtaacccat ccttgatatc tacaaaaata
     7081 tctctcccag taaaagcctt tttctcttga acttttgctt cctcttttgg aaggaaagcc
     7141 actagaacaa aagcaatgaa aaaagtcagc gagtctagca gtagcgtcat atggagactt
     7201 gcaaactgta aaacaaggaa ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc
     7261 agctctaggc gagaattata gatcacaatc tcatctttct ccaccacttc agttatgata
     7321 gctttattgg ctgtgcgaga aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc
     7381 aaagcgccaa tcatccagct atcattcctt atgaaagaaa tagccagaca aagaatccca
     7441 caaacaagat ctgccgtcat taaaatctta cgacgagaaa aacggtctga aataactccg
     7501 ccaaagggat tgacgagaat agatgtgacg agctcagaaa tctgatacat tcctaaaact
     7561 gtctgtccta tagtccccat agaagccaac cagacactat ttccataatc atagagcata
     7621 tttcccattt tattgatagc cccacggcta atcaactgca ctgcatagcg attcatatta
     7681 aagctcctct caaattttga aactattgta tcaaaaccga aaggagcttt ttattttttc
     7741 ccttatttgg gaaaattaac ttttgacaaa tttttcgtag tgttcctgat aataggctac
     7801 ttgctctgga agacctaaca catcaaaaat atgtatggcc tcttgcatct gcttacagcc
     7861 ttctttacac tgtccttttt gatataaggc aaaacctttt aaataatgga aaacattacg
     7921 ctcataaagc ttaatacctt tgtcaataat cttctctgta taagcctcaa aatagttggc
     7981 attataaaaa gaagaatgct ctaaacaatg ctggtaacaa ttgagggcca aaatcaaaac
     8041 taatctctta tggcgactaa tctcttggta aaattcctcc ctctccataa cttctctacc
     8101 aatccgagtg acatagtcta catcgtagaa actatagagg ttaccgaaaa gaatcaactc
     8161 atacatggtc cattcttctg ttttgaagag ataatctgct accttatcca aatcatcctg
     8221 cttcatatca taactcgcat ctctttgaca aatcagacct tgtagcaaaa tccagttcag
     8281 ctcaaaataa aggggagtcg tcgaactctt agacttttca agttgttctc tttgaagctt
     8341 ttgaaaacct gcaatatcgt ttgaatagta aagtgggata atctgtgcca tcatagacac
     8401 atgttcatga ttgtgaaaat tccttgcctt atccatgaaa ttttcgattg ttacatgaat
     8461 gttatccaaa atctcaaaga aacgggagac tgccaggtca gactccccaa gctcaaagcg
     8521 agataactga gaggtagagc aggattcgcc tgctgcttcc tttaaagaat aatttccact
     8581 tgttcgaaat tcacgaaata cttttccaag atgttccatc tttacacctg atctgataat
     8641 tcttcccact caagcatagc ttcttcctga cgatggctga ttttgtccag ctcagcctgt
     8701 aattccatga gtttgtcggc atcgtttgtt tccaacattt gttcagaaat ggcttggctt
     8761 tgactttcta gctcttcaat ttcagcttct agactttcga tttgtcgcat gagtttgcga
     8821 acttcttttt gactttcttt ctgggcctga tagtcattga ctggacttgc ttcctttgct
     8881 tgattgctag ttgaagcttc ctcagtctga ctcatttctg ctgttgcttt cttctcaaca
     8941 tagtagtcgt aatctccaag gtagagagtt gaaccattct cagacaattc caaaacatga
     9001 gttgccacac gattgataaa gtaacgatca tgactgacaa aaagcaaggt accatcaaag
     9061 tcaatcaaag cattttccaa cacttccttg ctatcaatat ccaagtggtt ggtcggctcg
     9121 tcaaggatca ggaagttgtt gttttccata gacaatttag ctaaaagcaa acgagctttt
     9181 tcgccaccag atagcatgcc gactgatttt ttaacatcat ctcctgagaa aaggaaggct
     9241 ccaagacggt tgcggatttc aacttctggt gtcagtttga aatcattcca gagttcatcc
     9301 agcaccgtat tacttggtgt cagcttgctt tgggtttggt catagtaacc aacctcaaca
     9361 ttagcgccaa agcgcttttc acctttgata aaaggaatct ggtccacaat agacttgata
     9421 aaggttgact tgccgatacc atttggacca acgatagcga cagcattcat cttacgaaga
     9481 tctaggttga taggttgtga caagacttcc ccgtcataac caatagcagt attttcaaca
     9541 gtcaaaacaa cattgcccga cgttttttca gactggaagg tcatgttggc tgctttcttg
     9601 ccagcttcag gcttgtccaa acgctccatt ttttctagtt gtttacggcg agattgagca
     9661 cgtttagtcg ttgaagcacg aactagattg cgattgacaa agtcttccag agcagcgatt
     9721 tccttctgtt gcttttcata gttttttgcc tcagtaacta gcttttgctc cttcaattcg
     9781 acaaaacgag agtaattccc cacatagcga tccaaggaat gcttggtcaa atctagcgta
     9841 attgtcgcaa ccttgtccaa gaaataacgg tcgtggctga cgataatgag ggcaccgcta
     9901 tagtttacca agtaattctc tagccaggcg atggtttcaa tatccaagtg gttagttggc
     9961 tcgtccaaga ccaagagatt gggcttttca aggagcattt tggcaagtgc caaacgagta
    10021 ttttgaccac cagaaagctc agcaattttc atctgccaca tagactcgtc aaacttgaat
    10081 ccattcaaaa tcgctcgaat atcagcttca taggtaaagc cacctgcttg gcgaaaattc
    10141 tcagataagc ggtcataatc tgacatcagt ttatccaaat cctcaccaga cttttcaccc
    10201 atctccagct ccatctgacg cagttgtctc tccgtccgac gcaaattatt aaagacatga
    10261 agcatttcat cgtagatggt attttcagac tcaaaacggc tatcttgggc taggtaagac
    10321 agagaaatat cttttttctt attgatttct ccgctagttg gctcctcttc tccaactaaa
    10381 atcttcaaaa gagtagactt acctgcacca tttttcccaa caagggcaat ccgatctcgt
    10441 tcatcaacct gcaggttgat attatcgaaa agaacctctc ctgcaaaaga acgttcaatt
    10501 ttattagctt gtaaaataat cataagagta gtatagcatg tttccctaag gcattcaaga
    10561 taatcgtaag tcttttagta caacttttat aacataaaat aaactaaatt atgtatattt
    10621 tatattagat tcttcactat cttgttggat tttctaacca gctaatcttg tttcaaatag
    10681 ttatcgcaca agcctattat ttaattcttt tcattattta cgtac
//
LOCUS       DAVHSH010000063        10433 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000063 DAVHSH010000000
VERSION     DAVHSH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.064"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..369
                     /locus_tag="VVR08_001802"
     CDS             <1..369
                     /locus_tag="VVR08_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6075660.1"
                     /translation="VSGRRYQRISLVAGLTNGELIVPMTYEETMTSDFFEAWFQKFLL
                     PTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLK
                     KVLPSCNTFYEALLSCSCFN"
     gene            269..715
                     /locus_tag="VVR08_001803"
     CDS             269..715
                     /locus_tag="VVR08_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6075661.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKKPIPKHLPPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAINVLDKVMKKIF"
     gene            complement(853..2157)
                     /gene="eno"
                     /locus_tag="VVR08_001804"
     CDS             complement(853..2157)
                     /gene="eno"
                     /locus_tag="VVR08_001804"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU6075662.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2321..2767
                     /locus_tag="VVR08_001805"
     CDS             2321..2767
                     /locus_tag="VVR08_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU6075663.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2764..3879)
                     /locus_tag="VVR08_001806"
     CDS             complement(2764..3879)
                     /locus_tag="VVR08_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU6075664.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3888..4217)
                     /locus_tag="VVR08_001807"
     CDS             complement(3888..4217)
                     /locus_tag="VVR08_001807"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU6075665.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4162..4533)
                     /locus_tag="VVR08_001808"
     CDS             complement(4162..4533)
                     /locus_tag="VVR08_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU6075666.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4592..6025)
                     /gene="glgA"
                     /locus_tag="VVR08_001809"
     CDS             complement(4592..6025)
                     /gene="glgA"
                     /locus_tag="VVR08_001809"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU6075667.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6022..7161)
                     /gene="glgD"
                     /locus_tag="VVR08_001810"
     CDS             complement(6022..7161)
                     /gene="glgD"
                     /locus_tag="VVR08_001810"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU6075668.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7151..8293)
                     /locus_tag="VVR08_001811"
     CDS             complement(7151..8293)
                     /locus_tag="VVR08_001811"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU6075669.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8283..10211)
                     /gene="glgB"
                     /locus_tag="VVR08_001812"
     CDS             complement(8283..10211)
                     /gene="glgB"
                     /locus_tag="VVR08_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU6075670.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3164 a         2297 c         1852 g         3120 t
ORIGIN      
        1 gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgagtta
       61 atcgttccaa tgacttacga agagacgatg acgagcgact tttttgaagc ttggtttcag
      121 aagtttctct taccaacatt aaccacacca tcggttatta ttatggataa tgcaagattc
      181 catagaatgg gtaagttaga acttttatgc gaggagtttg gtcataaact tttacctctt
      241 cctccctact cgcctgagta caatcctatt gagaaaacat gggctcatat caaaaagcac
      301 ctcaaaaagg tattaccaag ttgcaatacc ttttacgagg ctcttttgtc ctgctcttgt
      361 ttcaattgac tatataaatt gtctaagcga aacaaccgat aagaattggc acaaaagcga
      421 ccgtattttt gttaccaata taggaaaacc agttcatagt tctatcttga gcaagtctct
      481 ccagcgagca aacgaacgcc ttaaaaaacc aattcccaaa catctgcccc ctcacatctt
      541 cagacacacc actattagca tcttatcaga aaataaaatt cctttaaaaa caatcacgga
      601 cagggttggt cattccgact ctgaagtcac tacttccatc tacacccagg tcacaaagaa
      661 tatgaaagat gaagcaatca atgtactgga taaagttatg aaaaagattt tttaaaaagt
      721 tttgtccctt ttttgtcctc taaatacaaa aatagccctt cggataaaat ccgaggggct
      781 agaaacgttg ttaaatcaac ggccgaactt ttgaatttca tggttcggga taaaatagtt
      841 cactgaacta ttttattttt taaggttgta gaatgatttc aatccacgat attcagctac
      901 ttcaccaagt tggtcttcga tacgaagcaa ttggttgtat ttagcgatgc ggtctgtacg
      961 tgaaagtgaa ccagtcttga tttgtcctgc gttagttgca actgcaatat cagcgattgt
     1021 tgaatcttca gtttcacctg aacggtgtga tacaacagca gtgtaaccag cttctttagc
     1081 catttcgata gcttcaaaag tttcagtaag agtaccgatt tggttaactt tgataaggat
     1141 tgagttagca gcaccttctt ggataccacg tgcaaggtag tcagtgtttg ttacgaagaa
     1201 gtcgtcacca acaagttgta ctttcttacc aagacgttca gtaagagctt tccaaccatc
     1261 ccagtcgttt tcatccatac catcttcaat agtgatgatt gggtatttgt taaccaattc
     1321 ttcaaggtag tcgatttgtt ctgcagatgt acgaacagca gcaccttcac cttcaaattt
     1381 agtgtagtcg taaactttac gttctttatc gtagaattct gatgaagcac agtcaaatcc
     1441 gataaatacg tctttacctg gtacatatcc agcagcttca atcgcagcaa ggatagtttc
     1501 aacaccatct tcagttcctt cgaaacgagg agcgaatcca ccttcgtcac ctacggcagt
     1561 ttccaaacca cgtgatttaa ggattttctt aagagcgtgg aagatttcag caccgtaacg
     1621 aagggcttct ttaaatgttg gcgcaccaac tggcaagatc atgaactctt ggaaagcgat
     1681 tggagcgtca gagtgagaac caccgttgat gatgttcatc attggagttg gaagaacttt
     1741 agtgttgaat ccaccaagat agctgtaaag tgggatttca aggtagtcag cagcagcacg
     1801 agctacagcg atagacacac cgaggattgc attcgcaccc aatttacctt tgttaggagt
     1861 accgtcaagt gcgatcatag cacggtcaat agcttgttga tcacgtacat cgtagccaat
     1921 gatagcttca gcaatgatgt tgtttacgtt gtcaacagct ttttgtgtac caagaccacc
     1981 gtaacgagat ttgtcaccgt cgcgaagttc aactgcttcg tgttcaccag tagaagctcc
     2041 tgatggaacc ataccacgtc cgaaagcacc tgattcagtg taaacttcta cttcaagtgt
     2101 tgggttaccg cgtgagtcta ggacttcgcg agcgtaaaca tcagtaataa ttgacatttt
     2161 ttactctcct tatgagttaa attttttaca cctctataat accttaaaac ccctcctttt
     2221 tcaagaaaaa acgttatctt tgtgcaactt ttccttaact ttataaagta atcgctttct
     2281 tttgtctgtt ttattctaac ttttatgata tactgttttc atgacagatt tatcaaaaca
     2341 attacttgaa aaagctcatg gtgggttaaa aataaatccg gatgagcaaa gacgctatct
     2401 tggtactttt gaggaaagag ttcttggata tgtagatatt gacacagcaa atagccctca
     2461 gttagaaaaa ggctttttat ttattttaga aaaccttcag gaaaaagcag agccactatt
     2521 tgtgaagatt tcaccaacta tcgaatttga taagcaagtt ttctacttaa aagaagcaaa
     2581 agaaactgat agtcaagcca ccatagtatc tgaagagcat attacttctc cttttggcct
     2641 ggttattcat agcaatgcac cagttcaagt agaagaaaaa gaccttcgac ttgcttttcc
     2701 aaaactttgg gaagttaaaa aggaagaacc agccaaaaca tccttatgga agaaatggtt
     2761 tagctaaatc ttgcacatat ttaataagtg cccaatattg gcagccgtgc gctccagata
     2821 gagactggca tttttcaaac tatcttctaa aggttcactt ttctccaaaa tagaaaagac
     2881 agcttggata ttttcaaatg gtaggggagg taaatcttca gcaagactac cgcaaatagc
     2941 aataacagga actccaacag gggttctttt tgcaacacct ataggcgctt tcccagcaaa
     3001 gctttgactg tcaagtcttc cttctccaac aacaaccaag tcagcatctg aaactttctt
     3061 atcaaagttg attaagtcca agcaggtatc aattccagac acgatacttg cctgagcaaa
     3121 ggcacacaaa ccaccagcaa ggcctccacc tgctcctgct cctttaattt ctaatgttgc
     3181 aggtgagaat ttttcataaa aatcttggat cgcctgatct acgactgcaa acatagtcgg
     3241 atgtagacct ttttgattgc caaaagtgta agtcgcacct tgataaccac ataagggact
     3301 cacgacatct gctaaaatat gaatttgaac accttcagga attttatagc gattttctgt
     3361 tgaaacagaa gctaagttta ataaggattg accggaagca ggcaagacat ttccatccct
     3421 atcataaaat tgataaccta aaccagcagc aatccccagt cctccatcat tactggccgt
     3481 gccaccaaca ccgatataaa tatctttaat ccctttagaa atgagatgga gaatcaactc
     3541 tccaatacca caagtttgga tttgaagtgg atttcgtttc tctagcggaa tttttccaag
     3601 accaaccaag tcagctactt caaatagtgc cagttcccct ttttgaaaat agcgcatggc
     3661 ttctttttgt ccaaaagggt ctgtcacttg gatccatttt tcttttaggt caagagaatg
     3721 tcggatagca tctacagtac cttctccccc atcaccaaca gggcagagga gacattctac
     3781 atctgctatc gattgttgga agcctctttt tattgcttca gctacctgtt gagctgtcaa
     3841 gctttcctta aacgaatccg gtgcaattac aatcttcata ttttccctca ttctaaacag
     3901 tcaatcaaag gaagaacttc taaaaaatcc ctcttgtcaa catgatgtgg tatttctttt
     3961 ttgagcactt ctttggcaca aaaggcgatt cctaactccg ccgacttcaa cattaataga
     4021 ttattgaccc catcaccgat tgccaccgtt ctttctttag aaagttttag tttctttctc
     4081 catttttcca gagtttcttt tttgacctgg ggacttataa tttgtccaac taattttcct
     4141 gttaaaagac cttctttgac ttcaagctgg ttggcagtga aataggcaat accaagggat
     4201 tttgctaatc tctccaacta ttggtgtaaa tccaccagac accagaccaa ctaggatgcc
     4261 attcttttgg agaatagaga tgaactctgg gacatttagc gatagatgaa ttgagttgaa
     4321 gacgttatca aagaccaaaa taggaagacc ttccaacaag gacactcttt ttcttaaact
     4381 gctttcaaag accaactctc ctcgcattgc tcgacttgta atctgcgaaa tttccgcctc
     4441 atgacctgcc tctctcccta aaagatcaat cacttcttct aggattaagg ttccatctac
     4501 atccaaaaca cacaagcctt ttacttgaga catcagttct cctctctaaa cagcctaaaa
     4561 atcgtatgaa gtcatcatac gattttatct attaattaac taaactatgg tacaagtcaa
     4621 ggtatgactt gcaggctgta tcccatgaga agtcactctc catagcttgt ttttgtaggt
     4681 ttctccaaat gtctggatgg tttctataca agtccaatgc tgtttggaaa gtccaattta
     4741 accaataagg agatagattg tcaaagctaa agccagtacc gcttccttcg attggattga
     4801 aagcgcgaac tgtatctcgc aagcctccaa cttcatggac caatggcaag gttccataac
     4861 gcatagccat catttgagac aagccacacg gttcaaaacg acttggcatg aggaagaggt
     4921 cacaagcagc gtagatttcc tgagcaagtt tgacatcaaa agtgatattt gttgatagct
     4981 tgtctgggta aatctgagca aaccatgaga aagctccttc aaaggctgga tcgccagttc
     5041 ccaaaagaac aatctgaaca tcttcttgca agatatggtg aagactttcg accaccacat
     5101 caaaaccttt ttgacgtgtc aaacgagaaa caattcccac cagtggaacg tctgctctaa
     5161 caggcaagcc aactctttct tgcaattttg ccttattttt ggctttccca gacaaatctt
     5221 cctgattgaa atgatagtct aaaagagcat ccgtctgagg attataaaga tcagcatcaa
     5281 tcccattcac gataccagat actttaccag actccatttt aagaatctga tccaaattac
     5341 atccaaactg actagtcata atttcatgag catagctagg tgaaacggtt gaaacacggt
     5401 tcgcatagag aatacctgcc ttcatccagt tcagacagtt gttccatcga agggtgccat
     5461 cagcgtaacg ttcaaggcca actccaaaca aatcacccaa cattccttct gaaaattgtc
     5521 cttggaattc taaattatga atggttaaaa ctgtttcaat gtcctcatag gcttgaatcc
     5581 aacggtattt ttccttcaac aagaaaggaa tcatagctgt atggtagtca tgaacatgga
     5641 gaagatcagg aataaagtca atcctttcca tagcctcaat ggcagccagt tggaaaaagg
     5701 caaagcgttc tccgtcatca aaatcaccgt aaacatgacc acggaagaaa taatattgat
     5761 tgtcaataaa gtagaaggtt acaccattta atactgtttt cttaattcca caatactgtc
     5821 tgcgccaacc aacgctcacc tcaaaatgaa gcacatcttc aatctgattt ccaaatttag
     5881 cctctaccat atcatagtag ggtaaaatca ctgcaacttc gtgcccagct tttaccagtg
     5941 attttggaag agcgccaatg acgtctccca aaccacctgt ttttgaaaaa ggtgcaccct
     6001 ctgctgctac aaataaaatt ttcatgaatg aatatcctct gttactttag cacctttctt
     6061 aaccacaact ggatgttctg cagttcctcg aatcacaaca ccaggctcaa cttcaacccc
     6121 tttgtccaag atagcatatt cgacctgagc cccttttcca ataacaacac gagggaagag
     6181 caggctatct ttaaccaagc tatccttatg gacatgaata ttacgtgata gaacagaatt
     6241 agctacttga ccttcaataa tactaccaga ggcaaactga gaagtgctta ccttagatgt
     6301 attagcatag taagttggct cttcgttttt gacctttgta taaatctttt ggtttggtga
     6361 gaaaagagaa tagaattttt gtgattcaag catatcgata ttcgcttgat aataagattt
     6421 aacagagtga atattggcta gatagcccgt gtactcgtag gcgaaagctc cctcttttac
     6481 agccaaatcc cgtaaaacat agcgcaattt ctttggatgt tcttttttag cttcttcttc
     6541 caagtgttca atcaaccaag gtgtatcaac gacaaagata tctgtagaca tattgaacat
     6601 ttcagctgtt gacttgctat caaagagttt atgagaaaga acatggtctg tttcatctac
     6661 atccaagatt gcatttactt ctgaaatatc tttcttagct agttttttat aaactacagt
     6721 gataggctct tttgttgtac tatgtaggtg gaaaacttgg ttcaaatcaa tgttaataag
     6781 aacatcgcag ttgagggcaa ccgtttggtt tgagccagaa cgtttcaaat aagtaagaag
     6841 ctgttggtag tattcttttc caactgtact actttctaca cgggtattgt aaattcctag
     6901 atagtaatga ctaagaaggg ttgataagcc ccactcgcgt cctgaacgaa tatggtcaaa
     6961 tactgagctg atattatcct gctggaaaat accaaagaca ctacgaacac ctgcattagc
     7021 aaggcttgaa agtgggaagt caatcaaacg atatttccca ccaaatggca aacttgctac
     7081 tggacggtgg tccgtcaatg tcgacatatt gtgaaaacca actgtatttc ctaaaatggc
     7141 agaatattta tcaatcttca tctgttgcta cccccactac ttcattatat cctacaactt
     7201 gtacttcatc tgttccatca atttcgacac cgtcagaaat aatcgcacct tcaccaataa
     7261 tggcacgttt aatcttagct ccttgaccaa tgatagctcc actcatgata actgaatcaa
     7321 ggacttccgc tccttcgcga acttgcgcgc ctgttgaaag gatagaatgt ttaacagctc
     7381 catcaacgaa acatccgtct acaactaatg agtcttccac atgagcattt gccccgagga
     7441 agtttggtgg tgaaatcaag tttcttgagt aaatcttcca ttgacggtta cgactatcca
     7501 aggcattttc tggagaaata tactccatgt tcgcttccca aagtgactca atagtaccaa
     7561 catctttcca ataaccacta aattcgtaag cataaacact ttcacctgac tcaaggtaat
     7621 ttggaatgac atttttacca aagtctgaca tgccaacctt gctcttttca gcagcgacta
     7681 acatattacg aaggcgttgc caatcaaaaa tgtagattcc catagaagct tttgtagatt
     7741 taggttgagc tggtttttct tcaaattcaa caatacgatt gttagcatct gtgttcatga
     7801 taccaaaacg gcttgcttct ttaagaggga cgtccaaaac tgctactgtc aagctggcat
     7861 tattatcctt atgagactgg agcatatcat catagtccat tttgtagatg tggtccccag
     7921 acaaaatcaa gacatactca ggattgacac tgtcgatata gtcgatattt tggtaaatag
     7981 cgtgactagt tccctcaaac caacgatttc cttcacttgc agaataaggt tgaagaatag
     8041 agacgcctga attaataccg tctagtcccc agcttgaacc attcccaata tggttgttga
     8101 gagcaagtgg ttgatactgt gtaacgaccc caacattatg aatccctgag ttggcacagt
     8161 ttgatagggc aaagtcaatg atacggtagc gcccaccaaa ttgcacagct ggttttgcga
     8221 tgctttgagt gagtttaccg agacgagttc cttgcccacc agcaagaatc aaagctaaca
     8281 ttttattttt cattttctac tcctttttgg tttttatttg tgacggtttt agtagatttc
     8341 aagcgacgtt tgattttcca tacacttgct cccatagccg gtagagtaaa ggttaaggtc
     8401 tgctcataat ctttccatag gccttcttgc gtttgaacag tttgattatg ttctttccaa
     8461 acgcctcccc actcttccaa ctcagtattc catacttctt cgtaaattcc tgcaacgggt
     8521 agtccgattg taaaatcttt ccgctcaaca ggtaccatgt taaagataca gactaacatt
     8581 tctccctttt tacccttacg aataaaggaa agaacactct ggtctcgatt atccgcatca
     8641 atgatttcaa taccatcata gctggtatcg atttcccaca gacagcgatg atctttgtaa
     8701 aactggttta gctgagaagt gaaatacttc atcttagcat tcattgggtc ttctaggtta
     8761 gaccattcca actgttcttc agatttccat tctaggaatt gaccgtattc gctacccatg
     8821 aagagcaatt tcttaccagg gtgacaaatt tggtacgtat agagattgcg caagcctgcg
     8881 aattgattgt aacgatctcc ccacatctta tgcatcatac tcttcttgcc atgaaccact
     8941 tcatcgtgcg agaatggcaa gagataattc tccttgaaaa catacataaa gctgaaagtc
     9001 accaggttaa agtcatattt acgataaatc ggatcttctt cgtagaaacg gaggatatca
     9061 ttcatccagc ccatgttcca tttgtagtca aatcctagac caccaatctc tttcattccc
     9121 gtaatcttgg tcgcagacga actttcttct gcaatcatca tcacatctgg atattctaac
     9181 ttaataactt cattcaagcg ttgaagaaaa taataacctt catagttaag atttccgcca
     9241 tctttattag gtgtccatgg agcattatca tagtccaaat agagcatgtt gctaacagca
     9301 tccacacgaa taccatccaa atgatagaca tcaatccaat gcttaatgca agaaattaag
     9361 aaggactgga cttcattttt tccaaggtca aaattaaggg caccccaacc atggttatga
     9421 gccttattat ggtcttggta ttcaaaagtc ggtgtcccat cataataggc taaggcatca
     9481 tcgttgatgg taaagtgacc tggtacccag tccacaataa ccccaatatt atgggtatga
     9541 cactcctcga caaaatcttg aaactcctct ggtctgccat aagcatgctc taaagcgaag
     9601 taacccataa gctgataccc ccaactcaag cccaaaggat gggacatcaa gggcataaac
     9661 tcaatatgag tatagttcat ttcaacgaga taaggaatga gttcatcctt gagctgggca
     9721 aaactataag gactgccatc aggatttctc ttccaagagc cagcatgaac ctcgtaaata
     9781 ttgacaggac gttcaacaaa gccccaacgt tttcttcgtg ccagccaaag tccatccctc
     9841 catttcttat caggaagctc tgttacgatt gcccctgttc ctggacgagc ctcatacctg
     9901 acagcaaaag ggtcaatctt catcagttga tgaccatttt gacgtgtgac atgatatttg
     9961 taaatatgcc cttcttgagc catattggta aagacttccc agaccccaaa gtcatttctt
    10021 accattggaa tctgattttc aatccagttg gtaaaatcac caaccaagtg aacagcctga
    10081 gcattaggtg cccaaacacg gaaggtatag ccatgctctc catttagttc ttccctatgt
    10141 gctcctagat aatgttggag ataaaaattt tcacccgtca taaaggtttt taatgcttct
    10201 ctattatcca tatactcccc ttctcctgta agcgttttct atgtttttat tatactacct
    10261 ttttagagaa gattcaagta aattactata cttctttaat tattttgaaa atctacaaca
    10321 agttcactta ctcgttcaat tgtaaatcaa tattttttca aaaaattgcg aaaacgcctt
    10381 tctttttcta ctatagtgaa atgaaataaa acatgcgcaa atcgatcagg aca
//
LOCUS       DAVHSH010000064         9856 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000064 DAVHSH010000000
VERSION     DAVHSH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9856
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.065"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..351
                     /locus_tag="VVR08_001813"
     CDS             <1..351
                     /locus_tag="VVR08_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6075671.1"
                     /translation="EALITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVV
                     RLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKIS
                     EPEALYAYIAEATA"
     gene            389..691
                     /locus_tag="VVR08_001814"
     CDS             389..691
                     /locus_tag="VVR08_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6075672.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            699..1501
                     /locus_tag="VVR08_001815"
                     /pseudo
     CDS             699..1501
                     /locus_tag="VVR08_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1550..2014
                     /locus_tag="VVR08_001816"
     CDS             1550..2014
                     /locus_tag="VVR08_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU6075673.1"
                     /translation="MGGHPGFNCPLFDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYALFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2171..2596
                     /gene="lacA"
                     /locus_tag="VVR08_001817"
     CDS             2171..2596
                     /gene="lacA"
                     /locus_tag="VVR08_001817"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU6075674.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2627..3142
                     /gene="lacB"
                     /locus_tag="VVR08_001818"
     CDS             2627..3142
                     /gene="lacB"
                     /locus_tag="VVR08_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU6075675.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3153..4082
                     /locus_tag="VVR08_001819"
     CDS             3153..4082
                     /locus_tag="VVR08_001819"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU6075676.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            4084..5064
                     /gene="lacD"
                     /locus_tag="VVR08_001820"
     CDS             4084..5064
                     /gene="lacD"
                     /locus_tag="VVR08_001820"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU6075677.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            5298..6134
                     /locus_tag="VVR08_001821"
     CDS             5298..6134
                     /locus_tag="VVR08_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6075678.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6170..6487
                     /locus_tag="VVR08_001822"
     CDS             6170..6487
                     /locus_tag="VVR08_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6075679.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6487..8178
                     /locus_tag="VVR08_001823"
     CDS             6487..8178
                     /locus_tag="VVR08_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6075680.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8393..9799
                     /gene="lacG"
                     /locus_tag="VVR08_001824"
     CDS             8393..9799
                     /gene="lacG"
                     /locus_tag="VVR08_001824"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6075681.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
BASE COUNT         3101 a         1792 c         2054 g         2909 t
ORIGIN      
        1 gaagccttga tcacgcgtga aaagtcattt ccaactggtt tagatatgga atttctagga
       61 aaggacttgc caaatgtagc gattcctcac acagatattg ttcataattt ggctgaaaaa
      121 gttgtggtcg ttcgattaga gaaaccggtg actttccata atatgattgc gccagataag
      181 gaagtagaag tatccttgct cttctttatc attaataatt caagttcaag tcaaacgaac
      241 attcttgctc agttaatgga cttcttcaca ggaaatggtc atcttgaaga cctatcaaaa
      301 atttctgaac cagaagccct ttatgcttac attgctgaag caaccgctta atcttgtcta
      361 ttaaaaaata aaatcggagg aaatccaaat gattaaaatt cttgctgcct gcggtgcagg
      421 tgttaactca agtcaccaaa ttaaaagtgc tctagaagaa gaactttcaa accgtggtta
      481 cgatgttcac tgtgatgcag ttatggtgaa agatgtaaac gaagacctta tgaaaggtta
      541 cgatatcttt acaccaatcg ctgcaacaga ccttggtttt gaaccaggta tcccagttat
      601 cgaagctggg ccaatcttat tccgtatccc agcaatgagc gttccagtat ttgacaatat
      661 tagacttcct gcgaaacaaa acatggtata gtagttctat gaatgatgaa gcaagtaaac
      721 aactaactga tgcacgattt aagcgtcttg ttggtgttca gcgcacgact tttgaagaga
      781 tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta
      841 aattaagcct agaagacctt cttatggcca ctcttcaata tgtgcgagaa tatcgaactt
      901 atgaagaaat tgcggctgat tttggtatcc acgaaagcaa cttactccgt cggagctaat
      961 gggttgaagt aactcttgtt caaagtggtt ttacgatttc aagaactcct ctcagttctg
     1021 aggacacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa aaagaattag
     1081 cgaatgattc tggtaaaaag aaatgccacg ctatgaagtc tcaagcgatt gtcacaagtc
     1141 aagggagatt gtttctttgg atatcactgt gaactattgt catgatatga agttgttcaa
     1201 aatgagtcgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg gttatcaagg
     1261 gctcatgaag atatatcctc aagtacaaac tccacgtaaa tccagcaaac tcaagccgct
     1321 aacagttgaa gataaaacct ataaccatgc gctatctaag gagagaagca aggttgagaa
     1381 catctttgcc aaagtaaaaa cgtttaaaat gatttcaaca acctatcgaa atcatcgtaa
     1441 acgcttcgga ttacgaatga atttgattgc tggcattatc aatcatgaac taggattcta
     1501 gttttgcagg aagtctaata aagaaactag caaggtcagg ccttacttta ttggtggaca
     1561 tccaggattt aattgtcctc tatttgatga tgaagtctat gaagattatt atctagagtt
     1621 tgagaaagaa gagacttgct ctgttccacg tcctttccca gaaacaggta tgttggattt
     1681 ccaagataga agtccatggc tagagggaca aaaagaaata gatcttagtt atgctctttt
     1741 cagcaaagat gcagtgactt tggatgaatt gcaatctcga acaattgccc ttcgttctct
     1801 taaacatgat aggggattga aagtgcattt tgcagaattt ccaaacctca tcatctggtc
     1861 aactttgaac aagggacctt tcattacctt tgaaccatgg tctggcttgt caacattcct
     1921 tgaagaagga gatcatttag aagataagaa gaatgtttgt ctcttagaag ccaatcaggt
     1981 tgaagaatta gggtttgaga tagaagtttt ataaaaaagt aaaaaataaa taacaaaaac
     2041 aaacacaaac tgttgacttc ttcaaacaat agtagtatat tatgtttgtg aggactaatt
     2101 gactgttttt taaagacagc caatacactg ctggaatcca gcatagaaaa aataaaaagg
     2161 agtatacaat atgtctattg ttatcggtgc agatgctgca ggtttgagat tgaaagaagt
     2221 tgtgaaagac ttcttagaaa aagaaaactt ccaccttgtg gatgttacag ctgaaggtca
     2281 agactttgtt gatgtgactc tcgctgttgc tgcagaagta aacaaagaag aacaaaacct
     2341 tggtatcgtg attgatgctt atggagctgg tccatttatg gttgcaacta agatcaaagg
     2401 aatggttgct gcagaagttt ctgatgaacg ttcagcttat atgactcgtg gccacaacaa
     2461 ctcacgtatg atcactatgg gtgcacaact tgttggtgat gaattggcta aaaacatcgc
     2521 taaaggattt gttaatggta aatacgacgg tggtcgtcac caaatccggg ttgacatgtt
     2581 gaacaaaatg ggctaattag attatagtaa gaaaggtaag ttaaaaatga gaattgcaat
     2641 tggatgtgac cacatcgtaa cagatgaaaa aatggcggtt tcagaatttt tgaaatcaaa
     2701 aggatatgaa gtcattgact ttggtaccta tgaccataca cgtactcact acccaatctt
     2761 tggtaaaaaa gtaggggaag ctgtaactag cggtcaagct gatcttggag tatgtatctg
     2821 tggtactggt gttggtatca acaacgctgt aaataaagtt ccaggtgttc gttctgcctt
     2881 ggttcgtgat atgacaacag ccctttatgc taaagaacaa ttgaacgcta acgttattgg
     2941 ttttggtggt aaaattactg gtgaattgct tatgtgtgat atcatcgaag ctttcatcca
     3001 tgctgaatac aaaccaactg aagaaaacaa aaaattgatt gcgaaaattg aacatgttga
     3061 aagtcacaat gctcaacaaa cagacgcaaa cttctttaca gaattccttg agaaatggga
     3121 tcgtggagaa taccacgact aagaggtgac ctatgatttt aacagtcaca atgaacccat
     3181 ccatcgatat ttcctatccc ttggatgagt tgaagattga tactgtcaat cgtgtggtgg
     3241 atgtaaccaa aacggctggt ggtaagggac tcaatgttac ccgagtactt tcagaatttg
     3301 gcgattctgt tcttgctact ggtttagtgg gtggcaaact tggtgagttt ttggttgaac
     3361 atatcgataa tcaagtaaag aaagatttct tctcaattaa gggagaaact cgtaactgta
     3421 tcgctattct ccacggagac aaccaaacag aagttcttga aaaaggtcct gaagtattgg
     3481 aacaggaagg tcaagagttt ttggaacatt tcaaaaaact cttggagtca gttgaagtag
     3541 tagccatctc aggtagtctg ccagctggcc ttccagttga ttactatgcg agcttggtag
     3601 aacttgctaa tcaagctggc aagcctgtag tcttggactg ctcaggtgca gcacttcagg
     3661 ctgttcttga atcaccccat aaaccaacag tcatcaaacc aaataatgaa gaattgtctc
     3721 agcttcttgg aagagaagtt tctgaggatt tggatgaatt aaaagaagta cttcaagaac
     3781 ctttgtttgc agggattgaa tggattatcg tttcacttgg tgccaacggt acttttgcca
     3841 aacatggtga cactttctac aaggtagata ttcctagaat tcaggtggta aatcctgttg
     3901 gatctggaga ctctactgtg gcaggaattt cttcaggact tcttcacaaa gaatcggatg
     3961 cagaattact catcaaggca aatgtccttg gtatgctcaa tgctcaagaa aaaatgactg
     4021 gtcatgtcaa catggccaac tatcaagctc tatatgatca attaatagta aaagaggtat
     4081 aaaatggctt taacagaaca aaaacgtgta cgcttagaaa aactttctga tgaaaatggt
     4141 atcatctcag ctcttgcatt tgaccaacgt ggtgctttga aacgcctcat ggctcaacac
     4201 caaacagaag aaccaactgt ggcccaaatg gaagaactta aagtcttggt agcagatgaa
     4261 ttgactaaat atgcttcatc tatgcttctt gaccctgagt atggacttcc agcaactaaa
     4321 gctcttgatg aaaaagctgg tcttctcctt gcttatgaaa aaacaggtta tgacacaaca
     4381 agcacaaaac gcttgccaga ctgcttggat gtttggtctg caaaacgtat taaagaagaa
     4441 ggtgcagatg cagttaaatt cttgctttac tatgatgtag atagctcaga cgaactcaat
     4501 caagaaaaac aagcctacat cgaacgcatc ggttctgagt gtgtggctga agatatccca
     4561 ttcttccttg aaatccttgc ttacgatgaa aaaattgcgg atgcaggttc tgtagaatac
     4621 gctaaagtaa aaccacacaa agttatcggc gctatgaaag tcttttcaga cccacgcttt
     4681 aacattgatg ttttgaaagt tgaagttcct gttaacatta aatatgttga aggcttcgct
     4741 gaaggtgaag tagtttatac acgtgaagaa gcagcagcct tcttcaaagc gcaagatgaa
     4801 gcaacgaact tgccatacat ctacttgagt gctggtgtat cagctaaact cttccaagat
     4861 actcttgtat ttgctcatga atcaggtgca aactttaacg gagttctttg tggccgtgct
     4921 acatgggcag gatcagttga agcttacatc aaagatggtg aagcagcagc tcgcgaatgg
     4981 cttcgcacaa ctggatttga aaacattgac gaactcaata aagttcttca aagaacagca
     5041 acttcatgga aagaacgcgt gtaagaaagt cctcctagtt taggaacatg aatctaaaaa
     5101 aatttaaaaa aagttgtatg taaaggttta caaaacaacc gacttgtgct atacttaaat
     5161 cacaagttaa tacaaggtga gtgttactaa gtaatattag gcatgatcac aggtgaatta
     5221 gaaatcagct gattttctag ttcatttgtg gtcatttttt gtactcatat acctttaaga
     5281 tataaaagga ggttgacatg tatcgaattc taaatccaat gaatcacaat gtctcgcttg
     5341 tcagaaatga taagggagaa gaggtgatta taattggtaa ggggattgca ttcggaaaaa
     5401 ggaaggggga tttgattgct gaaaatcagg ttgagaaaat ctttcggatg aagaccgaag
     5461 agtccagaga aaactttatg gctcttctca aagatgttcc gcttgatttt atcacagtga
     5521 cctatgaaat cattgataag ctatcaaaga aatatcatta tccgattcaa gagtatctct
     5581 atgtaacctt gacagatcat atttactgtt cttatcaagc tctaactcaa ggaaggtaca
     5641 aggatagtaa tctgccggat atttccgcta agtatcctgt cgcttttcaa atcgcaaatg
     5701 aagcttttga aatttaccgt cagaagctag cagatcattt tcctgaggac gagattattc
     5761 ggattgctta tcatttcatc aatgccgaag gtgaaaatga agtggaactt gtggagtcga
     5821 ttgataagag gaaagaaatt ctcaggaatg ttgaagaagt gctaaagggt tatgcaattc
     5881 aacgaaccaa aaaaaataat catttctatg atcgctttat gattcatttg aattatttct
     5941 tggattattt agacagatct agagatgata accaatcact tctggatatg gaagatcata
     6001 ttaaacaatc ctatccaaaa gccttcgaga ttggttccaa gatctatgat gtgattacgc
     6061 aacatacggg tcttgatttg tataaaagtg aacgagttta tctagttcta catatccaac
     6121 gtttattgtc ataaaaattt atttaaaact atataaggag aattctatca tgaatagaga
     6181 agaagtaaca ttgttaggtt ttgaaatcgt agcctatgct ggcgatgctc gttcaaaact
     6241 attggaagcc ttgaaggctg ctgaagctgg tgattttgaa aaagcggacg ctctggtaga
     6301 ggaagctggt agctgtattg cagaggctca ccacgcgcaa acaagtctat tgactaagga
     6361 agcttcaggt gaggacttag cgtatagtgt gaccatgatg catggccaag accacttgat
     6421 gacaactatc ttgttaaagg atttgatgca ccatttgatc gaactctaca agagaggagt
     6481 taaataatga acaaactaat tgcatttatc gagaaaggaa agcctttctt tgagaaacta
     6541 tctcgtaata tctatcttcg tgctattcgt gatggtttca ttgcaggtat gcctgttatt
     6601 ctcttctcaa gtatctttat cttgattgcc tttgtaccaa actcatgggg ctttaaatgg
     6661 tctgatgaag ttgtagcctt tctgatgaaa ccttatagct attctatggg tattctggct
     6721 ctcttggtag ctggtacaac agctaagtca ttgaccgact cagtaaaccg tagcatggag
     6781 aaaaccaatc aaatcaacta tatgtcaacg ctgttagcag cgattgttgg tttgttgatg
     6841 ttggcagctg atcctatcga aaatggtcta gctactggat tcttggggac aaaaggtttg
     6901 ctttcagcct tccttgctgc ctttgttact gtagccatct ataaggtttg tgttaagaac
     6961 aacgtcacta ttcgtatgcc tgacgaagtt ccaccaaata tctcacaagt ctttaaagat
     7021 gtgattccat tcactctatc tgttgtttct ctttatgctc ttgatttact agctcgtcat
     7081 tttgttggtt ctagtgtggc agaatcaatc ggtaaattct tcgcaccact cttctcagca
     7141 gcagacggat accttggtat taccattatc tttggtgcct ttgccttctt ctggtttgtt
     7201 gggattcatg gtccatctat cgttgaacca gctatcgcag ctattaccta tgccaatgcc
     7261 gaagtcaact tgaaccttct ccaacaaggt atgcacgctg acaagattct tacttctggt
     7321 acacaaatgt ttatcgttac catgggtggt actggtgcga ctcttgttgt tccattcatg
     7381 ttcatgtggt tgacaaaatc gaaacgtaac cgtgcaatcg gtcgtgcttc agtagttcca
     7441 accttctttg gtgtaaatga accaatcttg tttggtgcac cgcttgtatt gaacccgatt
     7501 ttcttcattc catttatttt tgctcctatc gcaaacgttt ggatctttaa attcttcatt
     7561 gaaactcttg gaatgaattc atttactgct aatctaccat ggacaactcc agctccacta
     7621 ggtctagttc ttggaactaa cttccaagtg ctatcattca ttcttgctgc ccttctaatc
     7681 gtggttgacg ttgtcattta ctatccattc cttaaggtct atgatgaaca aattcttgaa
     7741 gaagaacgtt caggtaagtc taatgatgaa ttgaaagaaa aagttgctgc aaacttcaac
     7801 actgcaaaag cggatgctat tcttgaaaaa gcaggtgtcg atgcagcaca aaataccatc
     7861 actgaagaaa caaatgtcct cgttctctgt gctggtggag gtacaagtgg tctccttgca
     7921 aatgctctaa ataaggcagc agcagaatac aatgtccctg tgaaagcagc agcaggcggc
     7981 tatggtgctc accgtgaaat gttaccagag tttgatcttg ttatccttgc ccctcaagtt
     8041 gcttcaaact ttgaagatat gaaagcagaa acagataagc tcggtattaa actagcgaaa
     8101 acagaaggcg ctcaatacat caaattaact cgtgatggaa aaggtgctct tgcattcgta
     8161 caagcgcaat tcgattaagg ctagggactc tgaaatagtc tcctatcgtt acggaaatcg
     8221 ctatggcgaa tttcctaatc gccttattaa ttcgtcggta aaaagataac gtttttacct
     8281 cctcatgtca caattcagtg acttggtaca agaagtgaga tggagaagca tggctcactg
     8341 actcctctcc tctcactttt actttattta aatcaagaaa taggtgaaaa aaatgacaaa
     8401 aacacttcca aaagacttta ttttcggtgg cgcaacagct gcttatcaag cagaaggtgc
     8461 tacacatact gatggaaaag gaccagttgc ttgggataaa tatcttgagg ataactactg
     8521 gtacactgcc gaaccagcta gtgattttta caatcgatat ccagttgacc tcaagctagc
     8581 agaagagtat ggtgtcaatg gtattcgaat ttctattgct tggtcacgta ttttcccgac
     8641 tggttacggc caagtaaatg ctaaaggtgt tgagttttat cataatttat ttgcagagtg
     8701 tcacaaacgt catgttgagc cttttgtaac tcttcatcac tttgacacgc cagaagctct
     8761 ccactcaaat ggagacttct taaaccgtga aaatatcgaa cattttgtag actacgctgc
     8821 cttctgtttt gaagaatttc cagaagtaaa ctattggaca acctttaatg aaattggacc
     8881 aatcggtgat ggtcaatatt tggtggggaa attccctcca ggtatccagt acgaccttgc
     8941 caaagtcttc caatcacacc acaatatgat ggtgtctcat gcacgcgcgg taaaattgta
     9001 caaagagaaa ggctataaag gggaaattgg tgttgttcac gccctgccta ctaaatatcc
     9061 tctagatcct gaaaatccag cagatgttcg tgcagctgag ttggaagata ttatccacaa
     9121 taaattcatc ttagacgcaa cttatctagg tcgctattca gctgaaacca tggaaggtgt
     9181 caaccatatc ttatcagtca atggtggtag tttggatctt cgtgaagaag attttacaac
     9241 attagaagct gcaaaagact tgaatgattt cctaggaatc aactactata tgagtgactg
     9301 gatggaagcc tttgatggag aaactgaaat tatccataat ggtaaaggtg aaaaaggaag
     9361 ctctaagtat caaatcaaag gtgttggtcg tcgtgtagct cctgactatg taccacgcac
     9421 ggattgggat tggattatct accctcaagg tttgtatgac caaatcatgc gtgtgaagaa
     9481 agattatcct aactacaaga agatttacat cactgaaaat ggtctcggct ataaagatga
     9541 gttcgttgat aacactgttt acgatgatgg tcgtattgat tacgtgaaac aacacttgga
     9601 gatcttgtct gatgcgattg cagatggagc taatgtaaaa ggttacttca tttggtcatt
     9661 aatggatgtc ttctcatggt caaacggtta tgagaaacgt tatggtctct tctacgtaga
     9721 ttttgaaact caagaacgtt atcctaagaa atcagctcac tggtacaaga aagtagcgga
     9781 aactcagatt atagactagt agaattagtc attagatata gaattttagt gagtcaaaaa
     9841 gatgttcaaa gatttt
//
LOCUS       DAVHSH010000065         9657 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000065 DAVHSH010000000
VERSION     DAVHSH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.066"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            222..317
                     /locus_tag="VVR08_001825"
                     /pseudo
     CDS             222..317
                     /locus_tag="VVR08_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(570..1190)
                     /locus_tag="VVR08_001826"
     CDS             complement(570..1190)
                     /locus_tag="VVR08_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6075682.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1190..1672)
                     /locus_tag="VVR08_001827"
     CDS             complement(1190..1672)
                     /locus_tag="VVR08_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU6075683.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1672..2514)
                     /locus_tag="VVR08_001828"
     CDS             complement(1672..2514)
                     /locus_tag="VVR08_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU6075684.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2609..3397)
                     /locus_tag="VVR08_001829"
     CDS             complement(2609..3397)
                     /locus_tag="VVR08_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU6075685.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3541..4920
                     /gene="glmU"
                     /locus_tag="VVR08_001830"
     CDS             3541..4920
                     /gene="glmU"
                     /locus_tag="VVR08_001830"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU6075686.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLTGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4930..5475
                     /locus_tag="VVR08_001831"
     CDS             4930..5475
                     /locus_tag="VVR08_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6075687.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5487..5801
                     /locus_tag="VVR08_001832"
     CDS             5487..5801
                     /locus_tag="VVR08_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU6075688.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5818..6510
                     /locus_tag="VVR08_001833"
     CDS             5818..6510
                     /locus_tag="VVR08_001833"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU6075689.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFGEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6587..7078
                     /gene="rocS"
                     /locus_tag="VVR08_001834"
     CDS             6587..7078
                     /gene="rocS"
                     /locus_tag="VVR08_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU6075690.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7176..7766
                     /locus_tag="VVR08_001835"
     CDS             7176..7766
                     /locus_tag="VVR08_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU6075691.1"
                     /translation="MERLEDYIAFDLEFNQHEGQKHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     YGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7775..9538
                     /locus_tag="VVR08_001836"
     CDS             7775..9538
                     /locus_tag="VVR08_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU6075692.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2992 a         1674 c         2057 g         2934 t
ORIGIN      
        1 gtacacctga tatgatgcgt tttataattt taaagacttt ttgaccagcc tcattttttt
       61 aacttgatac tcagtgaaaa gcaaagatta aactagaaag ctagccgcag gctgctcaaa
      121 gaacagcttt gaggttgcag ataaaacttg tgaggtaacc aacatatata atgtgaagct
      181 gacgtggttt gaatagattt tagaagggta tgagtctgga agttttaatg gataatgcaa
      241 gattccatag aatgggtaag ctagagttct tatgtgaaga gtttgggcat aaacttttac
      301 cttttcctcc ctactcatct tagtatagaa aagtgaatct aaaatagtac ataactgctt
      361 ctaaaacatt cttataaatt gatttaaatt ctcaaatcat attattcagt tcttatttca
      421 ttttgctcta caatcctgtt gagaagacac gtgttcatat caaaaaggta ttggcaagtt
      481 gcaatacctt tttacaaggt tcttttgtct tatttttgtt tcaactgact atatctccta
      541 tggttctagt tcagaaggct aggctataat tatgattgat aagaagtatc attccaagta
      601 ttgagagtga atgtttcaaa atcatgggtt tctataatgg tcaggctggc atttgctaga
      661 ccgccatctt tacgaagaag tggttcttta tagcctagga gagtacgaag actggcagta
      721 agattggcgc cgtgtccgac aattagaata cgctcagctg gactatcttt taatgatttg
      781 ataaattgga tggtccgctg agttgtacta tagagggatt cggctccgaa cattcgagtg
      841 tcaaattgag caagatttga acgaaaagcc tggatttgtt gcgggtaaat agcttccagg
      901 gttgcaattt tcaaaccttc taacttccca agttgccatt cacggagatt aggaacgatt
      961 tctaaagaac agggggtata gagttgactt tggataatct cagcagattt gaccgctcga
     1021 ggtaaatcac ttgaataaat ctgatcaaaa ggaatttcct tgagatactg accaagtcgt
     1081 tttagggttt caatggattc aggaagaaga ggagaatcac cactagcacc ttgaaaacga
     1141 ccttcttggt tccagagggt acgaccgtgg cggacaaagt agagtttcat tacttgatgt
     1201 cctccaaaat atctacaaag tctgccttta caaagctagc caagtcttgt ggcgcgacga
     1261 taatgctgtg tccgacttcg cctgcagaga caatcatttg atccaaatct agagcaattt
     1321 tatcgataaa aatgggataa ttgtgtttct gacgaattcc gacaggatta ttggctccat
     1381 gaatgtaacc agttgttttt tctaagtcct tttgtggaat catgctcact tttttattgc
     1441 cagaaatttt agctagtttc ttttcagaca agtgctgagt gatagggaca attccgataa
     1501 tcggtccggt cttgtctccc aaaagcgcca aggttttgaa aatctgatct cgttcataac
     1561 cttgaggaag ctctccttct agggcattga tttgaatccc ctgatgaggg atagctgctt
     1621 tagataggat ttgttccacc aatgtttttt tgattttaac tttttttgcc attatttata
     1681 tttatcctcc aattgactca tccaaatacc aagccagatt cccagcgcaa agaagaaggc
     1741 gatgatgaca taaccgacaa gtgaaagtcc tgtgtattgg atactttcag cgtttcctgc
     1801 atttggaatt aagatcaaaa gggtacttga taggacgata ccgatgatga aatgatagac
     1861 gcgtgagtgg tagttgttta aggcataatc catcaatttt gaaaaaacga tgagagttgc
     1921 acctgcacca attccaatcg gaaagaaggt tcccaagaaa tcaaaagttt taaaaccagt
     1981 caacatagga gcatatagtc ccaaaatcaa aagtaaattt gatgggctga ggccaggaac
     2041 caagacgcca agggccaata gtgcgcctgc taggacgaag ttaagaaagc tggcgcttaa
     2101 ggttccaacg acaaaattta aggcatagag tcctaatcca gaaatgataa aggttgtcca
     2161 taaccaagct aaatcaatct tgtctcggtc agattctcga gttgattctt tgaggaggct
     2221 aggaactgta ccgataatag ctcccgcaaa gctccataat acaaaaacct gataattttc
     2281 aagcaggtat tcaatcgggt aggaaaataa gccgattccc agaagcatac cgatggcaac
     2341 tggaataaag tacaaaacat tttctttaaa gtctttaaag ggatgggcca gaaagccaat
     2401 cattcgttca tagattccta agattgctgc tagaacccct ccggaaattc ccggtaggat
     2461 aaatccaaga gcaattacaa tccctttaat aacgcgtgct aaccatgaga gcatatattt
     2521 cctccaacta tttctatttc aaaaaatcct tactatattg tatcacaatc agacacaaaa
     2581 agaaaaagca aatgataaac aaatgctttt aaggttttaa aaaaagtttt cgaaaggttt
     2641 cttctttatt ttttaaggga gagataacgt tgatatctaa atcgtggtca aagccggcaa
     2701 tttttccttt agatgtgtat tggtgaatat cataatctaa atcagtttta ggactgctct
     2761 ccaaaaatcc tgagtctgag ccgtaggacg gaatccaaac agaggtaaac ttgcctgtat
     2821 caatactgtg ttcttccatg aagtagacac caacgtagat gccgatgttt ttagcaccta
     2881 gtgatgctag ttttgctcga aagttttcga caccttcgtt catattagac atggttttgt
     2941 cttccacgtc aagccaatag taactagggc tgtaaggaga ggcagcattg tagaaaactt
     3001 cggcagcctt ttccatttct tggacacttt ttccagctac ataagcgtag acagcaactg
     3061 ggacattccg cttttgaagt tcagtgatat gactcttata ggccttgtct attccattga
     3121 taaatgaagc atcattttct tttgttgttt gagcaccact gtgaacacga acaatagcac
     3181 ctgaaatatt ttgtgagagg gcatcgtagt tgatttcctc aggacgctgc cagccagaga
     3241 ggtcaataat cggtttgtct aagtgtttca aagcctgtgc tatattggat tttgttttaa
     3301 acgattggct gtcattaagt gggcgattga tgattaaaat gaacatcata atcccaaaaa
     3361 aactaaataa aataagtgga tgaatttgtt ttctcatatc ttataagtct accctaaaaa
     3421 tcaaaaaaaa tcaaaaaaat gggttaagga agagacttta gagcattttt tcattcaaga
     3481 gtgcggaatg atttgaaata tggtataata aaagggaatt tctacagaaa agagaagatt
     3541 atgtcaaatt ttgccattat tttagcagcg ggtaaaggga ctcgcatgaa atctgatttg
     3601 ccaaaagttt tgcacaaggt tgcgggtatt tctatgttgg aacatgtttt ccgtagtgtg
     3661 ggagctatcc aacctgaaaa gacagtaaca gttgtaggac acaaggcaga attggttgag
     3721 gaggtcttga ctggacagac agaatttgtg actcaatctg aacagttggg aactggtcat
     3781 gcagttatga tgacagaacc tatcttagaa ggtttgtcag gacacacctt ggtcattgca
     3841 ggagatactc ctttaatcac tggtgaaagc ttgaaaaact tgattgattt ccatatcaat
     3901 cataaaaatg tggccactat cttgactgct gaaacggata atccttttgg ctatggacga
     3961 attgttcgta atgacaatgc tgaggttctt cgtattgttg agcagaagga tgctacagat
     4021 tttgaaaagc aaatcaagga aatcaacact ggaacatacg tctttgacaa cgagcgtttg
     4081 tttgaggctt tgaaaaatat caataccaat aacgctcaag gcgaatacta tattacagac
     4141 gtcattggta ttttccgtga aactggtgaa aaagttggcg cttatacttt gaaagatttt
     4201 gatgaaagtc ttggggtaaa tgaccgtgtg gcgcttgcga cagctgagtc agttatgcgt
     4261 cgtcgcatca atcataaaca catggtcaac ggtgttagct ttgtcaatcc agaagcaact
     4321 tatatcgata ttgatgttga gattgctccg gaagttcaaa tcgaagccaa tgttaccttg
     4381 aaagggcaaa cgaaaattgg tgctgagact gttttgacaa atggtactta tgtagtggac
     4441 agcactatcg gagcaggagc ggtcattacc aattctatga ttgaggaaag tagtgttgca
     4501 gacggtgtga cagtcggtcc ttatgctcac attcgtccaa attcaagtct gggtgcccaa
     4561 gttcatattg gtaactttgt tgaggtgaaa ggatcttcaa tcggtgagaa taccaaggct
     4621 ggtcatttga cttatatcgg aaactgtgaa gtgggaagca acgttaattt cggtgctgga
     4681 actattacag tcaactatga cggcaaaaac aaatacaaga cagtcattgg agacaatgtc
     4741 tttgttggtt caaattcaac cattattgca ccagtagaac ttggtgacaa ttccctcgtt
     4801 ggtgctggtt caactattac taaagacgtg ccagcagatg ctattgctat tggtcgcggt
     4861 cgtcagatca ataaagacga atatgcaaca cgtcttcctc atcatcctaa gaaccagtag
     4921 gagcctatca tggagtttga agaaaaaacg cttagccgaa aagaaatcta tcaaggacca
     4981 atatttaaac tggtccaaga tcaggttgaa ttaccagaag gcaagggaac tgcccaacgg
     5041 gatttgattt tccacaatgg ggctgtctgt gttttagcag taacggatga acaaaaactt
     5101 atcttggtca agcagtaccg caaagctatc gaggcagtct cttacgaaat tccagctgga
     5161 aaattggaag taggagaaaa cacagcccct gtggcagctg cccttcgtga attagaggaa
     5221 gaaacagcct atacagggaa attagaactc ttgtacgatt tttattcagc tattggcttt
     5281 tgtaatgaga agttaaaact atatttagca agcgatttaa caaaagtgga aaatccgcgt
     5341 ccgcaggatg aggatgaaac cttggaagtc cttgaagtga gcttagaaga agcgaaagaa
     5401 ttaatccaat caggtcatat ttgtgatgcc aagacaatta tggctgttca gtattgggag
     5461 ttgcagaaaa aatagaggag gtcagtatgg gtaaatcttt attaacggat gaaatgattg
     5521 aaagagctaa tagaggcgaa aaaatttcag gtcctccttt gctagatgat aatgaggaaa
     5581 ctaagatttt accaacctct tcttcccgtt ttggttatgc caatcctaag gatcatggtt
     5641 ttagccagga aaccttgaag attcaggtcg aaccatctat tcataaaagc cgtcgtattg
     5701 aaaataccaa gagaaatgtc ttcaattcta agttgaataa aatcttattt gcggtcattt
     5761 ttctcttgat tttgcttgtt ttagcaatga aacttttgta atagaaaagg aattgaaatg
     5821 aaaataggaa ttattgctgc tatgccagaa gaactggctt atctggtcca gcatttagat
     5881 aatgcccagg agcaagttgt tttggggaat acctatcata caggaaccat tgcttctcat
     5941 gaagtcgttc ttgtagaaag tggaattggt aaggtcatgt ctgctatgag tgtggcgatt
     6001 ttggctgatc atttccaggt ggatgccctt attaatacgg gttcagctgg ggcagtagca
     6061 gaaggtatcg ctgttgggga tgtcgtgatt gctgacaaat tagcctatca tgacgtggat
     6121 gtcacagctt ttggctatgc ttatggacaa atggcgcaac aaccgcttta tttcgaatca
     6181 gacaaaacct ttgttgctca aatccaagag agtttatctc aattagacca aaactggcat
     6241 cttggtttga ttgctacagg agatagtttt gttgcaggaa atgacaagat agaagcgatt
     6301 aagtcccatt tcccagaagt tttagccgtg gagatggagg gggcagctat tgctcaagca
     6361 gcgcatgccc tcaatctccc agtcttagtc atccgagcta tgagtgacaa tgccaaccat
     6421 gaagcaaaca tcttttttgg tgagtttatt atcgaagctg gacgtcgctc tgcccaagtc
     6481 ttgttgacct ttttgaaggc tttagattaa gcggaaattt gacagttttt ctagcttatg
     6541 ataagattta agtaaagaaa agctagaaaa cgtttcagag gatattatga gtattgaaat
     6601 gaccgtcagt gagattgcag aggtcttagg attatctcgc caagcaatca ataaccgtgt
     6661 caaagaatta ccagaagaag acacagataa aaatgacaaa ggggtaacag ttgttaccag
     6721 aagtggcttg attaagctag aagaaatcta taaaaaaacg atttttgaag atgagcctgt
     6781 cagtgaagat gtcaaacaac gtgaactgat ggagattcta gtggatgaga agaatgcaga
     6841 aattcttcgt ctttatgaac aattaaaagc caaggatcgt cagttatcag aaaaagacga
     6901 gcagatgcgt atcaaagacc gtcagattgc tgagaaagac aaacaattag atcagcaaca
     6961 acaattgacc cttcaagcca tgaaggatca agaaaatctt aagctagagc tggaccaagc
     7021 aaaagaagaa gtccaatcca ctaaaaaagg cttttttgct cgtttatttg gaggataatc
     7081 aaggagctgt ttaggttaaa tgctaacctg atggcttctt ttgtttgtga atagtatagt
     7141 tgattagaac agagacagta gaggagaggt acagaatgga acgattagaa gattacattg
     7201 cttttgactt agaatttaat cagcacgaag gacaaaaaca cttgattcaa gtatcggcag
     7261 tgcgttttag agatggtcgg gaaatcgatg cctatgattc ctatgttcat accagcgtcc
     7321 ctctaaaaag ctttatcaat ggtttgaccg ggattacagc tgagacctta aaagatgctc
     7381 ctccagttga gaaagtctta gaagaattcc aagagtttgt gggttctttg ctgatgatag
     7441 gctacaatgc tgctaaaagt gatttaccta ttttagcaga gtatggttta gactatagcc
     7501 aacagtacaa ggtggatttg tatgatgaag cttttgaacg tcggagttca gatttacatg
     7561 gtattgccaa tctcaaattg caaactgttg cctcatttct tggatttcaa ggtcagtctc
     7621 ataatagttt agaggatgct cggatgacgg cgcgtgttta cgaatccttc ttagagtcgg
     7681 atcaagctag ggaattgtta gagacagaaa gtagcttatc aaacaatcct tttggtggct
     7741 tggacttgtc tcaattattt gactaggagt gcctatgaaa cctgaaaaac ctaaaaaatt
     7801 gggtcttaaa cagatttacc tcaatcttga taaaatcctc tttctatttt tcttgatttt
     7861 tatgatagtg gagtatttgt gggtaccatt caattcatgg ttggctagct tcttattaga
     7921 tcagacaggt tatcttttta tttcctataa caatgtctta gccatcctta ctcattctcc
     7981 attgattagt ctagcttttt tagccttgat tgtaattaac cttctggttg cttattttca
     8041 aataggactc ctctttattg gtgctcgtca tctcctctat aatgaaaagc gaaggctaat
     8101 tgagtatatc cgcaaggttt tccatgaaag ttttggattt atgaaaaagc taacttgcgc
     8161 taaagccttg tttatctttt tctatatagc tatgcttttt ccttttatac ggaaaatgct
     8221 gaagatttat tatcttaata aaatcgtcat tccagagttt atccaagctt atttagaaga
     8281 taaatattgg atgtggtggc tgagcatcct acttctatct cttatctttc tctatgtctc
     8341 tgtcagattg atgtttgccc ttccgaagat tgtatatgat cagctgactg ttcgagaagc
     8401 agtgatgttt agcttggaga aaaccaagaa gagagttact ttttatgctt ggaatttatt
     8461 ttacatcttg ctcaaagcac atttattatt ttatcttcct ttgattcctt tattattggc
     8521 tcaaactttg gtagatgata tcactcagag agagtctctg attcttggta ttttgaattt
     8581 tgtcgtgatt aaaaatctct attatatggc tctgacttat tttttggtta aatttgtttc
     8641 atttttgaca ggaaaggagc tggatatgct tcctaggaga gaaaaagatc acatcgtgcg
     8701 atggggtgtc atgacttgtg ccagtctttt ctttgcctta gaaggttata tttatctgga
     8761 ggctcccatg gttcatctac ctcaacttat ttctcaccga ggggtttcca atgcaaatgg
     8821 gattcaaaat acagtagagt ccttggaaac tacagcacaa ctcaaaccag acttggtgga
     8881 gacggacgtg caggaaacaa aagatgggca gtttgtcatg atgcatgatg ctaacttgaa
     8941 aaatctagca ggtatcaata aaagtcctca agacttaaac ttggaggagc ttaaagggat
     9001 tgatattttt gaaaatggct accagactaa aatttcaagc tttgaagatt atctcagtcg
     9061 agccaacgaa cttggtcaaa aattactaat tgaaattaaa accagtaaaa aagatagtcc
     9121 agacatgatg aaccgctttt tagcccgtta tgctgcaaag ctcaagattt atggacatca
     9181 aatccagtct ttagactacc atgttgtcga aaaagtaaga cagtatgatg ccgaactgcc
     9241 agtttatttc atcatgccct acaattctgt ctttcctaaa acaagagcga caggatatac
     9301 tatggagtac tcaaccttgg atgaatattt tgtaagcaaa ctatggacaa cggatcagaa
     9361 actttatgtc tggactgtca atgattcaga agctatcagc aaatctcttc acttaggagt
     9421 agatggagtg attacagatg atttggaaaa agttcagcgg gaaatagaag tagcccaaga
     9481 agatccagaa tatacggatt tgctcttgaa aaaagcattg gaattctttg aattttagta
     9541 ataaaaaaga ggaacggttg ttcctcccat gataggtaag tattcttgtg aatgcttgct
     9601 tttttgtggt tgcaatccgt ttacgagaat tgtttgtatt gttcttgttt caattta
//
LOCUS       DAVHSH010000066         9637 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000066 DAVHSH010000000
VERSION     DAVHSH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.067"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(148..2598)
                     /gene="phtA"
                     /locus_tag="VVR08_001837"
     CDS             complement(148..2598)
                     /gene="phtA"
                     /locus_tag="VVR08_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU6075693.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(2851..4584)
                     /gene="ptsP"
                     /locus_tag="VVR08_001838"
     CDS             complement(2851..4584)
                     /gene="ptsP"
                     /locus_tag="VVR08_001838"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU6075694.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFNEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHSEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(4590..4853)
                     /locus_tag="VVR08_001839"
     CDS             complement(4590..4853)
                     /locus_tag="VVR08_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU6075695.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5204..5422
                     /gene="nrdH"
                     /locus_tag="VVR08_001840"
     CDS             5204..5422
                     /gene="nrdH"
                     /locus_tag="VVR08_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU6075696.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            5503..7662
                     /gene="nrdE"
                     /locus_tag="VVR08_001841"
     CDS             5503..7662
                     /gene="nrdE"
                     /locus_tag="VVR08_001841"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU6075697.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            7850..8812
                     /gene="nrdF"
                     /locus_tag="VVR08_001842"
     CDS             7850..8812
                     /gene="nrdF"
                     /locus_tag="VVR08_001842"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU6075698.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            8994..>9637
                     /locus_tag="VVR08_001843"
     CDS             8994..>9637
                     /locus_tag="VVR08_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6075699.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFN"
BASE COUNT         2819 a         1981 c         1789 g         3048 t
ORIGIN      
        1 tttcttaagt atatttgatt cactataaag taataaaccg gttaattaac tagttaatag
       61 tttactcttt ttaatattgc ttgtcaagaa ttttacatat atacataata aaaatgaaag
      121 cctctttatc gagactttca tttttcatta gtttattttt tccttactta cagatgaagg
      181 attacttcct tttaacaacg caagtaattt ttctgcttct gccatgatac tattgttatc
      241 cataatttga agagtcaaat tatttcgtaa accagctaga gtttctgttg cattggcttt
      301 cagactagaa tccgttactt tcgcaagcaa aacttctgct tctttgagtt gggcttctac
      361 tttttcagtc tctacttgag ggacttctgg ctcagcaggt gtttcctcta ctggctcttc
      421 atccgctttg aagttcttat ttggatcttc actgtggtct ttcttgccta acacatgctc
      481 actggcattg ccccatccat cattagaatg tggacgttcg tcagggtgtt ctacgtagta
      541 cttaatcgtc gcaaacaaat cttccaaggt atagccattt ggagctttgt atgtgtgatc
      601 atcaaaccaa gcaaatttaa tgttatggta atgatcctta tgaggaataa tcaaattacc
      661 gtttttaacc tcaactgtat gctcaaccat atatggaagt cgaacgagtg gaattcgttt
      721 ttcccctttc acacgattgt aaatagctgc tgcactatct ccagttggat ttgctttaac
      781 atctgcgtct ggagatggag gtaggatacc tttttcttta gtataggctt gagctgcaac
      841 tttttcctta tcagaaaggc tgtcttttcc aatccagtga ctatggccca tatgaggcgt
      901 tacatatgca tctccttcat cactgattat atcatgttca tcaaaaatgt aaccatctga
      961 cgttgtatac ttatcagcta attgagcaat acgaacttcg tcttcagtat actcaatttg
     1021 agaatttggc ttgccaagtc gctctggatg ggtaattggt gctaggaatg ccaataaatc
     1081 atctaccaat ttttctttat tagtcgattc atcattcaag cgttctaata atttgtctaa
     1141 ggcttggaaa tcagaattac gacccttatt ttcaaacaag gctttatgag cctcagttaa
     1201 cagattatat gctttatcat aaaattcttg gtcacgagga gcaacatttt cttttttagc
     1261 agttaaagtg tgtgaaacac tctcttgttt tgataacttg ctttcaagat ttttaacagt
     1321 ttcagatggt aaatctttcg caaagacata acgagagatg cccttttctt cgaatacata
     1381 tccttcccca acttttcgta ccagctgact aaccaaagaa gaatttgagt ctattttaag
     1441 atttggtgca ggttgcgggc ctggactagg ttccggagtc ggttgtggac ttggttgttc
     1501 tggccttgaa tctggtaccc aatggtttga acgataacga aggggaataa tacgagcgat
     1561 tcgttcttcc aattcagaca tttgagagta agggatgaag tggtaatgat ctccgtgtgg
     1621 cactgcaaca cctctagctg ttcgacttgt gatttgcgct gggtcgaaaa caaggccatc
     1681 agattctaca tgtcgttgac tcaaaggcag tttgtagagc tgtttcaaga gactatcaat
     1741 gtcattactt tgacttgttt gactgttagt gttgctgttg ttgcttgtgt tagtatttgt
     1801 agttcctgga ttgcttacag aaggtaccca gtttgttctt gaagtgttat cgctattttg
     1861 tcggcgatag gttcttgaat ttgacagatt tccccgacca gataggaagg cttctgcagc
     1921 agccaactcg ctagctgata actcattctt aggaatgtaa tggtaatgat ctccatgagg
     1981 aacgatataa gcatcaccag tatcctctat gatatcagaa gcattaaaga tataaccatc
     2041 atctgtagta tagcgtcctt gcgaacgtgc caaggcaaca gcaccatcgt ttcttggagt
     2101 cccaccttca cgatgttgac tatgttcttg tttttgtcga ttgatttcct cttttgtacg
     2161 gacgttatcc gcgtgggcag catccttaag gtaaacatag tattttccat ctaccttgat
     2221 aacatatcca cccttgacct cattaacaat atcctcatct tttagcttat agttcggatc
     2281 tttcatgagt aattcttcac tgaaaatcgc atcataagga accttaccat tgtaataatg
     2341 atagtggtcg ccatgtgaag tgacatagcc ttggtctgtt atcttgatga cgatttgctc
     2401 agcattgatt ccttcacgct tgctaacctc atcaggagtc aaattctccg ttttttgcgt
     2461 cgcttgtttt ccatctatat aggaaacacg attattttcc ttaaccgttc tagcttgata
     2521 cagtcccaac tcgtaagaac aaacacttaa aatcaaagct gccgcagaac caacaaggta
     2581 tttcttatta attttcatcg aaactctctt tctatttgat atttctagtt gcaattcatt
     2641 tttaaattgc agaaactcct ctctattact taactggtta atagtttact cctaaatctc
     2701 caacttgtca agaattttat gaaccattta agtatttttt gttctgacta ctactttttc
     2761 aagaaaatct ttctataaga aagattttct tgaaaattct ttttaaaata tcaaaaaaat
     2821 ccctgtaact gagttgcagg gacttttcga ttaatcaaaa ttaacgtatt ctttttgaag
     2881 ttcaaggact tcttccattg ttgaacactc tgtaagggca cggttagcgt actcttccat
     2941 cttagcagta tctaatttct tcatcaagct acgtgtacga aggacagatg ttgctgacat
     3001 agagaactca tccaagccca ttccgacaag aagtggaaca gctgtttggt caccagccat
     3061 ctcaccacac ataccagccc atttaccttc agagtgagct gccttaataa cgttgttaat
     3121 caagcgaagg attgatgggt tgtatggttg gtaaaggtat gaaacttgtt cgttcatacg
     3181 gtctgctgcc attgtatatt ggatcaagtc gtttgtacca attgagaaga agtcaacttc
     3241 tttagcaaat tggtctgcaa gcatagccgc tgcaggaatc tcgatcatga taccaacttg
     3301 gatgttatcc gcaactgcaa caccttcagc aagaaggttt gctttttctt cattaaagac
     3361 tgctttcgct gcacggaatt ctttcaagag cgcaaccatt gggaacatga tacgcaattg
     3421 accgtgaaca gacgcacgaa gaagagcacg gatttgtgtg cggaacatag cgtctccagt
     3481 ctcagagata gagatacgaa gagcacggaa tccaaggaat gggttcattt cgtgaggcat
     3541 atcgaagtaa ggaagttcct tatctccacc gatatccatt gtacgaacga caacaggttt
     3601 accgttcatt ccttcaagaa cagccttgta tgcttcatac tgctcatctt cagttgggaa
     3661 gtcttgagaa tccatgtaca agaactctgt acggtaaagt ccaacagctt ctgcaccgtt
     3721 gttgttaaca ccttcaacgt cttttggagt accgatatta gcagccaact cgaagtgttt
     3781 accgtcagca gtcactgttt gagcatcttt caagagcgcc cattcagctt tttgtttcgc
     3841 ataagcttca ccagctgctt taaattctgc cgcttgttca tcagttgggt tgataataac
     3901 ctcaccagtg atcccgttaa cagcaaggat gtcaccgtct ttaacgattt cagtgatgtt
     3961 gtttgtacct aatacagctg caatttcaag tgtacgtgcc atgatagctg agtggcttgt
     4021 acgtccaccg atgttggtta caaaagcttt tacaaagttt ttgtccaatt gagctgtatc
     4081 agatggtgtc aagtcatgtg caatcacaat cacttcttca ttgatagaag ctgggtttgg
     4141 taatttttta ccaagaaggt ttgccaatac acgttttgtc acgtcgcgga tatccgctgc
     4201 gcgttcttgc atgtatgggt tgtcttccat gccttcaaag atagtgataa acatatctgt
     4261 aacttctttc agacctgctt ctgcattcac tttcttcgca cggatagttt ccttgatttg
     4321 gctgatcatt tctgggtcag caagaaccat taagtgagca tcaaaaactt gagctgcttc
     4381 ttcaccgagc gtacctactg ctttctcgcg aataacagaa agctcgtctt gtgatgcctg
     4441 tagagcggca tcaaggcgag cttcttctgc gtttgtatct tcgactgtaa tagtctcaaa
     4501 tgacaaatcc ggctgaacga gtagatatgc ttttgcaact gcaacaccgt cagatgctgc
     4561 gattccttta agcatttctg tcatttccct tatgccaatc cttctttttc cattgtttct
     4621 gagattgcag cgatagcgtc atctgcatct gcaccttcag ctgagatagt tacgtcagca
     4681 ccttgaccaa caccaagact cataacaccc ataattgatt taaggttaac tgatttacct
     4741 ttgtactcaa gagtgatatc tgaagcaaat ttgctagcag tttgtaccaa caatgttgct
     4801 ggacgtgcgt gaatacctgt ttctgccact acgtggaaat ctttagaagc catagtttga
     4861 ctctcctttt gttctttctt tttttgagtt atatgtgata acccttacaa tttagtatta
     4921 taccatcttc taggattttt ttcaagcatt ttctggattt tccttcaatt tcctttcaga
     4981 taacttgctg aaaatcttct atcctagata acaaaacaca ggatatagtt tctttaaaaa
     5041 caatttatag gataatcatt gctatttcac aatacaaaca ctatatattg tgtttatata
     5101 taaaaacaac aaaagaacac cactatattt agttcaaatc attgacaaaa ttttattttc
     5161 tgatatacta agatagtatt aaattttgaa gaggagttac acaatggtaa ccgtttattc
     5221 taaaaacaat tgtgtccaat gtaaaatgac caagcgtttc ttggacagta ataatgtctc
     5281 ttatcgtgaa atcaatcttg atgagcaacc tgagtacgtc gatcaagtta aagagctcgg
     5341 ttttagcgca gctcctgtta tccaaacacc aactgaagtc ttttcaggtt tccaaccagg
     5401 aaaactgaaa caattagcat aatcttagta catcatccag aagaaactgc ttttagggct
     5461 aacttagaag cctttctttt gtaattagat aagggaaatt ttatgggatt aaaacatctt
     5521 gaagacgtga cttacttccg tcttaataac gaaattaacc gtcctgttaa tggacaaatc
     5581 atgcttcata aagataagga agccttggat gctttcttta aagaaaatgt agttccaaac
     5641 actatggttt ttgattcaat caaagacaaa atcaattacc tcattgaaca caactacatc
     5701 gaaacagcct ttatcaagaa ataccgtcca gagttcttgg aagaattggc tcaatttatc
     5761 aaagaccaaa acttccaatt caagtcattc atggcagctt ataaatttta caatcaatat
     5821 gccttaaaga ctaatgacgg tgaatactat cttgaaaata tggaagaccg tgtcttcttc
     5881 aacgcccttt atttcgctga tgggaatgaa gctgttgcaa tcgatattgc caatgaaatc
     5941 atccaccaac gctaccaacc tgctactcct tccttcttga atgctggacg tgctcgtcgt
     6001 ggggagttgg tatcttgttt cctaatccaa gtgacggatg atatgaactc tatcggacgt
     6061 tctatcaact cagctcttca actttcacgt attggtggtg gtgtgggaat taccctcagc
     6121 aaccttcgtg aagctggtgc acctatcaaa ggctatgaag gagctgcttc aggtgtcgtt
     6181 cctgttatga agctttttga agacagcttc tcttactcca accaattggg gcaacgtcaa
     6241 ggtgctggtg ttgtctacct caacgtcttt cacccagata tcatcgcttt cctttcaact
     6301 aagaaagaaa acgctgatga aaaagtacgt gtcaagactc tatcacttgg tgttgtagta
     6361 cctgataaat tctacgaatt ggctcgtaaa aatgaagaaa tgtacctctt cagcccttac
     6421 tctgtagaaa aagaatacgg tgtgccattc aattacatcg acattactga aaaatacgat
     6481 gaattggtcg caaatccaaa tattcgcaag acaaaaatca aggcgcggga tttggaaact
     6541 gaaatctcta aattgcaaca agagtctggc tatccttatg tagtcaacat cgatacggct
     6601 aaccgtgcaa atcctgttga tggaaagatt atcatgagta acttgtgttc tgagattctt
     6661 caagttcaag aaccaagctt gatcaacgat gctcaagaat tccttcaaat gggaacagat
     6721 gtttcatgta atctgggttc aaccaacgtg gttaacatga tgacttcacc tgattttggt
     6781 cgttctatcc gtgctatggt tcgtgccctt actttcgtta cagatagttc acatatcgta
     6841 gctgtaccaa cgattgacca tggaaatagc caagcccaca cctttggtct cggtgccatg
     6901 ggactgcaca gctaccttgc ccaacaactc attgaatatg gttcacctga gtctgttgaa
     6961 tttacaagca tctactttat gcttatgaac tactggacct tggtagagtc aaacaatatt
     7021 gcgcgtgaac gtggtattac cttccacaac tttgaaaaat cagactatgc taacggaagt
     7081 tactttgaca agtatgtaac tggtgaattt gttccaacat cagaccgtgt taaagaactc
     7141 ttcaaaaatg tttttatccc tggtgttgct gattgggctg aacttcgcga caaggttcaa
     7201 gaagatggtc tttaccacca aaatcgcctt gctgtagcgc caaatggttc tatcagctat
     7261 atcaacgacg tttctgcttc tatccacccg attacgcaac gtatcgaaga acgccaagag
     7321 aagaaaattg gtaaaatcta ctaccctgct gctggcttgt ctacagaaac cattccttac
     7381 tacacttctg cctacgatat ggatatgcgt aaagtcatcg atgtttacgc tgctgcgact
     7441 gaacacgtgg atcaaggact ttcactcacc ctcttcatgc gcagtgacat tccaaaaggc
     7501 ctttacgaat ggaagaggga aaataaacaa acgacacgtg atttgtccat ccttcgtaac
     7561 tatgccttta acaagggaat caagtctatc tactacgtcc gtacctttac agatgacggt
     7621 ggagaagtcg gcgccaacca atgtgaaagc tgtgtgattt agtttctagc atagaaacat
     7681 tatttttccc taagcagcac tgataaaatc aaatctacta tgtcataaca taatttatgt
     7741 aacattttaa aagtcgggct tccgactttt tgtgcgatac tcctatagaa ttatggtaaa
     7801 gtagaaataa ttgtgagttc gcaatactaa acacagaaag agattttaaa tggaaactta
     7861 ctacaaagcc attaactgga atgccatcga agatgtcatc gacaaatcaa cttgggaaaa
     7921 actgacggag caattttggc tcgatacacg tattccctta tcaaacgact tggatgactg
     7981 gagaaagcta tctaacaaag agaaagactt ggtcggaaaa gtttttggtg gtttaaccct
     8041 tcttgacact atgcaatctg aaactggggt tcaagccctt cgcgcagaca tccgtacacc
     8101 acatgaggaa gctgttttca ataacatcca atttatggaa tctgtccacg ctaaatctta
     8161 ctcatcaatc ttttctacct tgaatactaa ggctgagatt gaagaaattt tcgaatggac
     8221 caataccaat ccttacctac aaaagaaggc tgagattgtc aacgaaatct acctaaacgg
     8281 cagcccactt gaaaagaaag ttgccagcgt cttcctcgaa accttcctct tctactctgg
     8341 tttcttcact cccctctact atctcggtaa caacaaacta gccaacgttg cagaaatcat
     8401 taaattgatt attcgtgacg agtctgttca cggaacctac attggttaca aattccaact
     8461 tggtttcaat gaattgcctg aagaagagca agaaaaactc aaagaatgga tgtacgacct
     8521 actctatact ctttatgaaa atgaagaagg ctacacagag agtctttatg acggtgttgg
     8581 ttggactgaa gaggttaaaa ccttccttcg ctacaatgcc aataaagctc tcatgaacat
     8641 gggacaagat ccacttttcc cagattcagc tgaagatgtc aacccaatcg ttatgaacgg
     8701 tatttcaaca ggaacttcca accatgactt cttctctcaa gtcggaaatg gttaccttct
     8761 tggcgaagtt gaagccatgc aagacgatga ctataactac ggtttagact aattctccat
     8821 cactctcaat catcaaaaag taaactagaa acatcaaagt tataacccaa caaaaatatc
     8881 gaaagttttg aaaacaaact tcgatatttt tgtttttgtt tcattttgtt gtttttgtat
     8941 ttgaatgatg agtttgttta tggtaagata gtagtaggaa acgaggtgat aatatgctca
     9001 aacaagaaaa attaaccaaa attttagaga tagtaaatag taaaggaacc ataacagtta
     9061 aacagattat ggacgaaata gccgtttcag atatgactgc aaggcgctat ttacaggaat
     9121 tagctgataa agatttgctg attcgtgtgc atggtggagc tgaaaaactt cgaaccaact
     9181 cccttttgac taatgagcga tcaaatattg aaaaacaagc cctccaaacg gcagaaaaac
     9241 aagaaatagc ccattttgca ggcagtctag tagaagaaag agaaactatt ttcattggac
     9301 caggaacaac attagagttt tttgcgcgtg agttgcctat tgacaatatc cgcgtcgtaa
     9361 ccaacagtct acctgttttt ctgattttaa gcgaacgaaa attaacagat ttgattttga
     9421 taggtggaaa ttatcgcgat attacaggtg cttttgttgg cacattgacc ctacaaaatc
     9481 tctctaatct ccaattttct aaagctttcg ttagctgtaa tggtattcaa aacggagctc
     9541 tagctacttt tagcgaggaa gagggagagg ctcaacgcat cgctttaaat aattctaata
     9601 aaaaatattt actcgcagat catagtaagt tcaataa
//
LOCUS       DAVHSH010000067         9510 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000067 DAVHSH010000000
VERSION     DAVHSH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.068"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(152..906)
                     /locus_tag="VVR08_001844"
                     /pseudo
     CDS             complement(152..906)
                     /locus_tag="VVR08_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
     gene            complement(976..3627)
                     /locus_tag="VVR08_001845"
     CDS             complement(976..3627)
                     /locus_tag="VVR08_001845"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU6075700.1"
                     /translation="MSKELSSKYNPADVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(3620..4198)
                     /locus_tag="VVR08_001846"
     CDS             complement(3620..4198)
                     /locus_tag="VVR08_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6075701.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(4198..4758)
                     /locus_tag="VVR08_001847"
     CDS             complement(4198..4758)
                     /locus_tag="VVR08_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6075702.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(4745..5062)
                     /locus_tag="VVR08_001848"
     CDS             complement(4745..5062)
                     /locus_tag="VVR08_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075703.1"
                     /translation="MERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFA
                     KILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKD
                     GKN"
     gene            complement(5606..6001)
                     /locus_tag="VVR08_001849"
     CDS             complement(5606..6001)
                     /locus_tag="VVR08_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6075704.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(6097..6351)
                     /locus_tag="VVR08_001850"
     CDS             complement(6097..6351)
                     /locus_tag="VVR08_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU6075705.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(6361..7695)
                     /locus_tag="VVR08_001851"
     CDS             complement(6361..7695)
                     /locus_tag="VVR08_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU6075706.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQERFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIADESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(7695..7928)
                     /locus_tag="VVR08_001852"
     CDS             complement(7695..7928)
                     /locus_tag="VVR08_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU6075707.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPIMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(8390..8572)
                     /locus_tag="VVR08_001853"
                     /pseudo
     CDS             complement(8390..8572)
                     /locus_tag="VVR08_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8574..9353)
                     /locus_tag="VVR08_001854"
     CDS             complement(8574..9353)
                     /locus_tag="VVR08_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075708.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYTF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT         2715 a         2158 c         1791 g         2846 t
ORIGIN      
        1 ataaaagagt tataatcagc actactgata aattcaatac cgatttcgcc atcttaaaac
       61 ttagtcaaac gaataccgtt gatttccagt tcattaagtc gttgacctat caagacttct
      121 cgttccttca actggaaaag ttaaggggga actaatacaa atcctctacg cttctatatt
      181 caatgatttc atttttgata atattctttt taaactcaaa atgttttaaa ggattatcga
      241 ttaacactaa ctttggaata tcatctagat ttgtgaccaa ggataaaata aaatccgatt
      301 gaaactcctt gactttttca aattcttttg cagttaaacg cacacgcccc ttagattttc
      361 ggataccttt tacttcggca aggtaagaat actcttggac atctacctga aagtcatatc
      421 catcaccata aagacgggca tcggttaact gtccaccttg gaatttttct tctttatcaa
      481 aatgaaggat aaaataattc tcagcctcca ttcccgtttc ctgtagacgt ttgaatttag
      541 ttcgaactat tggtttttca acgatggtta tgcctgtttt cttcccttca ctggcaagta
      601 acattttaac tattcagcat aactatgaac atcttcattt ccaaacatca tatcaattaa
      661 atctttacga aaacgataaa cttcagcttt ctgccaccaa ccttttcgat tattgtcaaa
      721 ataaggatca aataaatcca ttctattttt tacaactcca gttgtttcag caattcccag
      781 agaaaccaca tagcgataaa actccgactt gctagagcat tgaaattctt ttataaaaag
      841 cttgtcaaac ttggcaagac cgtagccaat taaatttaac aattcataat gagggtgttt
      901 ggacatcact ttctccatca atagatattg atttcattat accaaaaaac acggctcatc
      961 accgtgtttc tgtgtttatt tcaccaactt cttcatctca tcaatacgtg ctacggtcac
     1021 atcatacttg gcttggtagt cggcttgttt gtctttttct ttttggacaa cttctggttt
     1081 agcgttggcg acgaagcgtt cgttagagag tttcttacca accatgtcca gttctttttg
     1141 ccatttagcg agttctttgt cgagacgagc tagttcttct tcaacattga ggagatcggc
     1201 cagtggcaag aagatttcgg ctcctgtaat aacgcttgac atagccagtt caggtgcagg
     1261 gatggttgat gcgatttcca agtgttctgg atttgtaaag cgtttgatat agttgacatt
     1321 gctgttaaag aaggcttcca agtcgctatc gcttgtctta acaaggatgg tgataggctt
     1381 gcttggtgct acatttactt ccgcacgcgc attccgaaca gcacgaatca agtctttgag
     1441 actttccaca ccagtgtgag ccgcaaggtc ttcaaaggct agattaacag ttgggtatgc
     1501 agctgtcacg atagaacctt ctgagatttg tccaaagatt tcctctgtca cgaatggcat
     1561 gattgggtga aggagacgaa ggatcttgtc caaagtgtat agtagaacag aacgtgtgat
     1621 gactttctct tcttcgttat cgctataaag gacttccttg gtcaactcaa cataccagtt
     1681 ggcaaattct tcccaaatga agttgtaaag gatatgacca gccacaccaa actcgaactt
     1741 atcaaagttt tcagtaactt ttgcaatggt ttcgttgaga ttgtggagaa tccagcggtc
     1801 cgtcacatta ccagcctcac ctgttgcaac ttttgtgaca ttgtcatgcg ccacatccag
     1861 cgtcaaacct ccattgttca tgaggatata gcgagaaatg ttccaaatct tgttaataaa
     1921 gttccatgaa gcatccattt tctcataaga gaaacgcacg tcttgtcctg gcgcagaacc
     1981 gtttgaaagg aaccatcgaa gggcatcggc accgtatttc tcgataacat ccattgggtc
     2041 aatcccgtta ccgagagact tagacatctt gcgtccttgc tcgtcacgaa tgagaccgtg
     2101 gataaggacg ttttggaatg gttgacggcc tgtgaattcc aatgactgga agatcatacg
     2161 agacacccag aagaagatga tgtcgtaacc tgttaccaag gttgaagttg ggaaataacg
     2221 tttaaagtct tctgagtcga cttcaggcca gcccatggtt gaaaatggcc agagggcaga
     2281 actgaaccaa gtatccaaga cgtcttcgtc ctgagtccat ccgtcacctt ctggagcttc
     2341 ttcgccgaca tacatttcac catcagcatt gtaccaggca gggatttggt gaccccacca
     2401 aagctgacga gagataaccc agtcgtggac attttccatc cattgaagga aggtatcgtt
     2461 gaaacgaggt gggtagaatt cgaccttgtc ctctgtgtct tggttggcaa tggcgttctt
     2521 agccaattgg tccatcttga cgaaccattg agtagacaag cgtggctcaa ctacgacacc
     2581 tgtccgttct gagtgaccga ctgaatggac acgtttttcg attttgacaa gggcaccgat
     2641 ttcttccaac ttagcaacga ctgccttacg agcttcaaaa cgatccatgc ctgaaaattc
     2701 aaaggcaagc tcattcatag ttccgtcgtc gttcatgacg ttgacttgtg gcaagttatg
     2761 acgttggcca accaagaagt catttggatc gtgggcaggt gtgattttca cgacaccagt
     2821 accaaactca ggatctgcgt gctcatctcc aacgattggg atgagtttat tagcgattgg
     2881 aaggatgacg tttttaccaa tcaagtcctt gtagcgcggg tcttctggat taatcgcaac
     2941 cgcaacgtcc ccaaacatag tctcaggacg agttgtagca acttcaaggg cgcgtgaacc
     3001 atcttccagc atgtaattca tgtggtagaa ggcaccttct acatccttgt gaatcacctc
     3061 aatatcagaa agggctgtgc gagctgctgg gtcccagttg atgataaact caccacgata
     3121 gatccagcct ttcttgtaaa ggtccacaaa gaccttacga acagcttttg acaaaccttc
     3181 gtcaagagtg aaacgctcac gagaatagtc tacagaaagc cccatcttgc cccattgttc
     3241 cttgatggta gtggcatatt cgtctttcca ttcccagacc ttcgtcaaga aagactcacg
     3301 acctaggtca taacgcgtaa taccctcacc acgtaagcgc tcctcaacct tagcctgagt
     3361 cgcaatacca gcgtggtcca tacctggaag ccaaagggta tcaaagccct gcatgcgttt
     3421 ttgacggatg atgatatcct gcaaagtcgt atcccaagcg tgaccaaggt gaagtttccc
     3481 agttacgttt ggtggtggaa tcacgattga ataaggctta gccttttgat cgcctgaagg
     3541 cttgaaaaca tccgcatcaa gccatttttg gtaacgacca gcctcaacat cggctggatt
     3601 gtatttagat gaaagttctt tagacatgtg tgtgtccttt ctctattttg tttattttat
     3661 tttgaatttg cttagcagct tcttctgcag acaaattcgt attatttatt ttaaagtagt
     3721 ggtgcaactc attcggttga tattgggaat ttaattgaag tgtttcagcg gtctctaaaa
     3781 tttctctttc agatacctca atatgtcgtt ttaagggttt gtgctttaat cgattctccg
     3841 ttcgatttcg acgtatgcac tcttcaagac ttgtttccaa ctcaacaaaa agaatctctt
     3901 gatgataatc atccaacaaa ttctgaattt gctttaaata catcagctga tactgatttg
     3961 aaaaatcaat tacatctgtt aaaattactg atcgctgatt tcttgcactt gctccaagga
     4021 atgaaaaagt gattccacga acaaattccc acatttcctc tgtatagtcc tgatagattt
     4081 ctagtgcaaa atcaatggct tgatggttat aaaatagggt agcatccgtc agtcgagata
     4141 attcttgacc aatggtcatt tttcctgatg ctggagcacc aatgatgaaa agatgcatca
     4201 aatcacctcc cactcactct tcagcaaggc atatctcaaa tcatcacagc agttgccttg
     4261 agcatcttta cggtctctta tgcgagcttc gagggtaaag ccaagctttt ccgcgactcg
     4321 ttgactttga aggttatatc caaagcaagt tagttcaatc ttgtgaagac ccaaatcttt
     4381 aaaggctaag tcaatcaagg cacgcgcagc ttctggcaca taacctcgcc cccaatagtc
     4441 tgagtgtaag gtatagccga tttccatcac atcatcttca tggcgatggt tgaaatagat
     4501 agagccaacg atcttatccg ttcctttgac gacaatcccg tagcctgctg ggagattttc
     4561 cttttgatta cgctccggaa gaatgtgctc cagataataa atctcatctt ccaaggtctt
     4621 gactggagga aaacctgctg gataggcgac ctctggcaaa ctagcatagt caaagatatc
     4681 ctcagcatcc gccacagtac ggactcgtaa aacgagacgt tctgtttcga ttttatctgg
     4741 cagctcagtt cttgccatcc ttcttcctcg cttttttgat gaaactgccc ttcatatcta
     4801 cacgcttgtc cagatagcga taaacgcgct gatatccatc tcccatgaaa taggttgggg
     4861 caaacagttg atttttaaaa tgtccctttt catccaggag ttctggggca acaagtcgct
     4921 caagaatctt ggcaaagatg tggcaaatac cgtcttcctc aacaatccta tctacccgac
     4981 aatctaaaac aagtggacag gcgtctaaaa taggaatctg agttcgttca gaaatttcat
     5041 aatgcactcc caaacgttcc aatttctcct gatgactgat aaaaccagcc tactccatcg
     5101 caagcataga agtttcatca gaaatattca cagtaaattt ttgatactgt ttgatctgct
     5161 ctgcggcatt ctctctcgca acgactccaa tcacaaccca atctcctaga ctataagagg
     5221 aactacaggt cgtgatgtta tagccaaaat tctaatcttg atatcctaaa ataaaaacag
     5281 gaaaaccata atatagttta ttagttttaa atgattgttt tataacaacc tcctttgact
     5341 aagacacaaa agaaaagccc tgccatctac atgacaggga cgaatgtgtt tatccgcggt
     5401 accacccaat ttcgggccaa gcccgcatct ttagtcttta aaataaaaag acagaaatat
     5461 ttcatttttt cagtcattag caaccagttt tgacacattt gtggacttct cagcgccgcc
     5521 actttctgta aaatgtggga ttcaaaacac ctctaatggc tctattgtag caagtttttc
     5581 tcggaaatgc aaggctcaag aaaaattact tgaacttgat gccattttct ttcaatttct
     5641 tgatggtagc tgggccgatt cctttcaagg caaggagttc tttttcagtc cagtttttga
     5701 aatctgaagc agacttgatt ccttcatcat agaaagtttt ggcacgatca agtggaagtc
     5761 cacccaagtt tgctgcaaaa tcttctacag aattagctac tttttgagct tgctctttgg
     5821 tagcttctac tgcttgttca acttttttag aaacagcctt accagctgcg cttgctgact
     5881 gttctgcacg cttcacgact ttttttgtct catctacaac cttagtcaca gtacttgaaa
     5941 aggcacctgc gcgacggagg ccatttcgta attgtttttt acgattgagt ttctttgaca
     6001 tgataaaatc ctttcaataa aaaatccctg ctctgacaag gatttaacat aaacattcta
     6061 tcaagatttt agtgaaaaat caagaatctt tctcgtttaa taatttcgct caccaaacaa
     6121 gccttctggc aaatcatgga atcccttgcc tgctttgaag ttttcaaact taccaagcaa
     6181 gaactgataa gcatccaagc gactctcgta gcgaatcatg gcatctttgg cacgctcgtc
     6241 ctggtcttct tcgtaaactt tttgactttc cttgtgcgcc atgtcgttaa tcatgatttg
     6301 ggtattgacc caagcttcaa attccttcat aaattcttgt tcgtaactca ttttttctcc
     6361 ttattctaat ccacgaaaat agtccgtatc aatctcacgg tagggctgga tatcctgaac
     6421 atactccaac actccttgga attctccgtc ttcatcgtgt actgcagcat aggtgatgtg
     6481 gacaaactta cctcgcgact cagacttgaa ccacatttca tacttgtcct tggtcccctc
     6541 acgaagcccc ttcatgatag ttttgacctt gtccaaatac ttaggcggat gacagagttc
     6601 gacattgcgc ccgacttggg acggcgtccg tttgaaaatc atctcatcag ctggcgtatt
     6661 gtcattgtaa tactggaaaa tatcttcttt attgacaaag gtaatctcca tagggagatg
     6721 attgaggatg agattggcct gctcgactga aagatagcca ttaccaaaag cctgttgact
     6781 atggcggtcc agcacagctt ccttttcctt aggggtaaag gtaatggtaa aatggccttc
     6841 tggcgtatct atgacttgtt gaacttgacc ttctgccgta tctagctgta caggctcctc
     6901 tgcaatcttt tcctcaataa agctctgtcg ttctggcacc catttctctg acggacggat
     6961 gatggcatag ccataggcat cgctctcatc cgcaatctga agccagtcat cctgagtaaa
     7021 agactcaagg agaatcatga ggaggatgga ctcttccttg aaaatcatac tttcaaactc
     7081 tgtcgcaaaa gcttcaaaag cttcctttac actgctaatt gacacttctg gtagtgactt
     7141 ggctgtcgtt agagctgttt gaaagagttc cctaatctga tcatccactc cccacataac
     7201 tttgggaggt gaatcgtgtc catagcgctc catgatagga aagaagagtt cttccttacg
     7261 ttggtaatgg atgtcaaatt gccccacaag tcccatctga cgcaccaagc ccttgcgcat
     7321 ctccgcaagc atttcctcgt cttccataga ctcataggta tctaacaatc tacgaatgcg
     7381 aatcaaagct gcacggaggg ccaaattttc ttccttaaag acacgaactg ggtgcccagg
     7441 gtgttcggta tctaaaactt cgacaccttt gatagcattt ttaaaaagat tggcatggac
     7501 atcacagagt tccataacat cttcaaaagt gacgcccgaa tccgagttca tcagctcgtg
     7561 ctccataagg gaaatctcga tggctgacac gcccgtaaag gtcgcatcaa agcgctcttg
     7621 aaccgactca ggagaggcgc cattgtgcaa ttctaacaaa atatcccgta ggatatgaat
     7681 ccgttcatct gtcattagtc taatccaatc acttcgtagc cattcgcttc cagtgtgcgt
     7741 acaatcttgt ccataggagt tcctgctagc ttagaaccct gtttaagtga tactttacga
     7801 ccaactgtat tgcgcattat gggattggca aggggtttaa aacccaactc cactagaatt
     7861 tccaagactt ctggatgctt gtccaccact tctgcaacag gaattgacac atcgatgata
     7921 ttgtccatga cgacctccat tgtatgttct aatactcaat gaaaatcaaa gagcaaacta
     7981 ggaagctagc cgcaggttgc tcaaaacagt gctttgaggt tgtagataga actgacgaag
     8041 tcagctcaaa acaccgtttt gaggttgtgg atagaactga cgaagtcagt aacatatata
     8101 cagcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgattttact
     8161 gcttatatta taccatatgg aaagagaata aaaaactagc agtggagttc ctgctagttc
     8221 tctgcgactt ggattaccat ctagataagt ttaaagagcc aatccaatat cttaaacact
     8281 atcttgtaaa acagcaattg gactgcaaaa gagatgatca tccaaaagaa tttcacaatc
     8341 ccaataatcg gtttgataaa aataatggca agaagtcccc agaaaaattt cattttttat
     8401 cctctggctt aatgagccac cgagccgtat ccattaactt gtcggcaata aaaagtttcc
     8461 ccagaccgac aacggcatta tcatctttct ttatcgtttt cattactttt acaccttaca
     8521 cggtcaaaaa gtaattacca taaattttag ctagagtttt tatgagtccc atattactct
     8581 ccttcgatga tttcagcctc ttttcggatt gtttcaacat cttcttgata ttgaacttca
     8641 ctatagttaa ctagcttgga caattctttc tgcaagcttt cacccatcgg tttcatagtt
     8701 gcaaaggtta aaccacctga aatgatacca cccaagatag gaataaattt ccctattcct
     8761 ttggccagcc ctcccttggt aagattcaca ccaaatattt ttaagacttt tttcaaaata
     8821 gggtaccaaa gcgtctttgt taaagcttta ttaggcactg ttttcattac ctgtttggca
     8881 attgttatac caccagcacg tagcaaagca gcggttccat tcacccccaa catgacgcct
     8941 agataaagca agagggtatt ttgagcatct tcactcaact cctcgcgtga agcccaaaga
     9001 tcctcataac cataaatata acctaattct tgagccaatt ttagagagaa agtataaaat
     9061 tgagccacat cagctggaat ggtaattgcc atagcaagcc ctccaggtaa tcctgccaaa
     9121 acagaagtcc cactcgctaa taaaacatta tccctaatac aggcattagc cactcgatct
     9181 aagatttctt gagataagag agacgttgga ccttgttcca ataaggtagg aatgtcctgt
     9241 ggacccaatt ctttggaaaa cttatccact aaaaatttcg aacgatcaac cttaacaaca
     9301 ggtagtttca ccacttgttg caatacttgc atagctaagt cttgttcagc catatacaaa
     9361 ctccttattt cttttttgca ccttatcata ttatatttcc tacaaaaaaa gcattttcta
     9421 attagataac attaaaaaat acagaacccc ttttttatag tgaaatgaaa caagaacagg
     9481 acaaatcgat caggacagtc aaatcgattt
//
LOCUS       DAVHSH010000068         9410 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000068 DAVHSH010000000
VERSION     DAVHSH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.069"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..132
                     /locus_tag="VVR08_001855"
     CDS             <1..132
                     /locus_tag="VVR08_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6075709.1"
                     /translation="PPLALQNEFADFVAQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            192..428
                     /locus_tag="VVR08_001856"
     CDS             192..428
                     /locus_tag="VVR08_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU6075710.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            425..838
                     /locus_tag="VVR08_001857"
     CDS             425..838
                     /locus_tag="VVR08_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU6075711.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            956..1921
                     /locus_tag="VVR08_001858"
     CDS             956..1921
                     /locus_tag="VVR08_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6075712.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNCSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            1944..2525
                     /locus_tag="VVR08_001859"
     CDS             1944..2525
                     /locus_tag="VVR08_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6075713.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            2555..5905
                     /locus_tag="VVR08_001860"
     CDS             2555..5905
                     /locus_tag="VVR08_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6075714.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEEQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            6149..6250
                     /locus_tag="VVR08_001861"
                     /pseudo
     CDS             6149..6250
                     /locus_tag="VVR08_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6492..6962)
                     /locus_tag="VVR08_001862"
     CDS             complement(6492..6962)
                     /locus_tag="VVR08_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6075715.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(6979..9252)
                     /locus_tag="VVR08_001863"
     CDS             complement(6979..9252)
                     /locus_tag="VVR08_001863"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU6075716.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFAYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEVELEVKLPHKIELEEPQLNLVQPQGQAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         3045 a         1544 c         1968 g         2853 t
ORIGIN      
        1 cccccactag ccctccaaaa tgagttcgca gactttgtag cccaggtcga caaatcacaa
       61 ttggcaatcc aaaaatctct ggaagaactt gaaactttga agaaatctct gatgcaggag
      121 tattttggct gatattctgc cattgtaatt acggtaatga tttgttataa tacttcaaag
      181 gaggaaatca gatggtagta aaaacaagaa aacaaggaaa ttcaatcacc attacgattc
      241 caagtgaatt taatattcca agtggtgtta aatacgaagc gaaattgtta ccaagtggtg
      301 agattatctt tactcctgaa gaattggggc agcaggtttc ttatgtatct gatgatgcct
      361 ttgacttaaa tttagataaa atatttgacg aatacgacga tgttttcaaa gctttggtgg
      421 aaaaatgaca atctatctga cagaaaagca aattgaaaaa ataaatgctt tagcaattca
      481 acggtattct ccaaatgaga aaattcaaac agttagttct tctgccttaa atatgattgt
      541 gaacttacca gaacaatttg tctttgggaa gtctctttat ccaacaattt ttgataaagc
      601 aacgatacta tttgtccaat tgataaagaa gcatgttttt gctaatgcta ataaaagaac
      661 tgctttcttc gttttggtca aatttttaca attaaacggc tatcgttttt ctgtaacggt
      721 agaagaagca gtaaaaatgt gtgtaaccat cgcagtagaa gctttaactg atgaaaaaat
      781 gacaagctac tccaaatggg tttctgaaca ttctgttaga gaaaaggtca aaaagtaacc
      841 tagtatgctg gatttgaatg agcacaagaa aataaatgaa cagacaatat tagaattctg
      901 taatgcagaa actgatattg tctcttttta ttgatgaata agaaagtgag aaattatgga
      961 atcaaaagtt acaattatca tgcaagaaat gttacctctt ttaaataatg aacaattact
     1021 agcgttgaga gagagtttag aacatcatct agtagacgga aaaaagcagc agaagtattc
     1081 gaataataac ctgttgcaac tatttattac cgccaagcag gtagagggct gtagctcaaa
     1141 aacaattcgt tattaccaga ggacgattga aaacttgttt aatgctatta aagagtctgt
     1201 gacacaactc acaacagatg atttaaggag ttatttagca aattaccagt ctgaaaagga
     1261 ttgtagtaag gcaaatttag acaatattag gcgtatattg tcttcttttt ttgcttggct
     1321 tgagcaagag gaatatatca ttaaaaatcc cattcgacgg ataaagaaaa ttaagactga
     1381 gcaaaatgtg aaggaaactt atactgatga acatttggaa attatgcgtg ataactgtga
     1441 aaatttgaga gatttggcaa taatagacct actagcatcg acaggtatgc gtgtagggga
     1501 gcttgtacag ttgaattgtt cagatattga ttttgaaaac agagagtgtg ttgtctttgg
     1561 taaaggaaag aaggagagac cagtatattt tgacgctcgg acgaaaattc atttaagaaa
     1621 ttatcttaac gacagaaaag atagtcaccc tgctcttttt gtaacgctag ttggaaaagc
     1681 ccagagactt ggaattgctg gtgtagagat tcgcttaaga aagttaggag acaaactcgg
     1741 catacaaaag gttcacccac ataagttcag aagaacttta gcgactaagg caattgataa
     1801 aggtatgcct atcgaacaag tccaaaaact gctaggtcat agcaagattg acacaaccct
     1861 ggcctatgcc atggtcaatc aaaataatgt caagcattca caccaaaaat tcatctctta
     1921 aaagcaaatc ccgatttaac gagatgtttg gggaaaataa aatatttgaa agcattgata
     1981 acttatttga tattatagat ggtgataggg gcaaaaatta tcctaaatca gatgagttgt
     2041 ttagtgagga gtactgttta tttttaaata caaagaatgt tactaaaaac ggattttcat
     2101 tcgatacaaa gcaatttatc actaaaacaa aggataaatt acttcgaaaa ggcaaacttg
     2161 agcgttatga tatagtcttg acaacaagag gtactgttgg aaatgtagcg tactacgatg
     2221 aattaataaa atataaacat ttacgtataa attcaggtat ggtaatatta cgtcccaaga
     2281 caccaaatct aaatcagaaa tttattatcc atgttttaag gaataataat tatagtcgag
     2341 tgatatcagg aagtgctcag cctcagttac caattacaaa attaaaaaaa atacttctcc
     2401 ccctcccccc actagccctc caaaatgagt tcgcagactt tgtagtccag gtcgacaaat
     2461 cacaatttgc ttgtgagata gctataaaag tgtggagaaa tagcttgaaa tttagtataa
     2521 tatagctaaa ctatttgttt aaagtgagaa aaaaatggga aattttagct ttcttttaaa
     2581 aaatgacgaa tatgaatctt tttcaaaacc ttgcattgaa gctgaaaata tgattgctac
     2641 atcaactgtg gctactgcct ttatggcgcg tcgtgctttg gagcaggctg tccattggat
     2701 atatagtcac gattcatatt tagaagctcc ctatcgtgct actctatctt ctttagtatg
     2761 ggatgatgat tttagggata tcgtagattc tgaactccac aagcagatag ttctgttgat
     2821 tcggtgggga aaccatgctg ctcatggtgg tgaaattaag gaacgagaag cgattttagc
     2881 tttacatcat ttgtatcagt ttgttaattt tatcgattat tgttacagca atgaatttgt
     2941 ggagcgttat tttgatgaga agtgcttacc actttcagca aacatcaaat accgagaaac
     3001 tccacaatct atgataaagt tacaagacag tttaccagaa ctgcctgatt ttcatgaaca
     3061 gatggctgct cagtccgtag aagttcaaga gacttatact gaaaaacgtg agactgcagc
     3121 gcaacggcaa gatgtgcctt tccatattga acaattatct gaggcagaga caagaaagct
     3181 ctttattgat atcgatctcc gtttagcagg atggatattt gaagaaaact gtcgtgttga
     3241 gatagccgtt gatggtctca agcacggttc aggaattggt tactgtgact atgtacttta
     3301 tggtaaaaat gggaaaattt tagcgattgt ggaggctaaa aaagcctctg tcaatccaga
     3361 agtaggggaa gtacaggtca aagaatatgc tgaagctttg gagaaacata tcggctatca
     3421 gccaatttgc tttattacaa atgggttgaa gcactatata cttgatggtc cgaaccgccg
     3481 ccagattgca ggcttttact ctcaagaaga attgcaatta gtgatggata gacgtcatct
     3541 tcaaaaaccg cttgaggata tttctagtaa aattagggac gatatttccg ggcgtcacta
     3601 ccaaaaacat gccattgcaa gcgtttgtga agctttctct aatcatcgta gacaggcact
     3661 tttggttatg gcaactgggg cggggaaaac tcgtacagca gtttctctag ttgatatctt
     3721 atcacgtcat aactgggtaa aaaacgttct cttcttagcc gatagaactt ccttggttaa
     3781 gcaagcctat gattcgttta gaaaattact cccagatctt tccgtttgta acttcttaga
     3841 agataaagaa ggagctcaat caagtcgtat ggtcttttca acttatccga ccatgattgg
     3901 agcgattagt ggtcaagaag aagtaaatca acgccctttt actgttgggc attttgacct
     3961 tatcataatt gacgaatctc accgttctat ttatcagaaa tacaagtcca tttttgatta
     4021 ttttgatgca agaattgtag gcttaacagc tactccgcgt caagatttag ataaaaacac
     4081 ctatggattc tttaatttgg agaatggggt tccaacatat gcatatgatt tggaagaggc
     4141 tgttaaagac ggatatttag tagcctatca ttctatcgaa accaaactga aactacctac
     4201 ggatggtcta cattatgatg atttgtccga agaagaaaag gaacattttg atagcaaatt
     4261 tgaagacgat agctgtgaaa aagatattga tgggagtgta tttaattcct ttgttttcaa
     4321 taaaagtaca gtagaaattg ttttaaatga actcatgaca agaggaattc agacagcctc
     4381 gggtgatgaa attggtaaaa ctattatttt tgctaaaaat catgatcatg cggaatatat
     4441 cagaggtatt tttaacaacc gctatcctga aaaagggagc gactatgctc aggtgattga
     4501 ttatagtatt aagcattatc agaccttgat tgatgatttt aaaattaagg agaagtatcc
     4561 tcaaattgcg atttctgtcg atatgttaga tacaggtatt gatgtaccag aggttgttaa
     4621 tttagtcttc ttcaagaaag tacgctctaa aactaagttt tggcagatga ttggtcgagg
     4681 aacccgtcta tgtaaagatt tatttggacc tgagcaggat aaggaaaact tcttggtatt
     4741 tgattatggg gacaattttg attattttcg tgcagatcca agagatggag agggtcgtca
     4801 cattgtttcg ttgactcagc gtttatttaa tatcaaagtg gacttgattc gagaacttca
     4861 gggactccaa taccaagaag aacagtttgc gagagcatac cgtcagcagc ttgtctcgga
     4921 acttcaaggt cgtatagaga gcttaaatga gttggacttc agggttcgta tggttttaga
     4981 tacagtttat agctatagga aattggaaag ttggcagaat ctaactgctg ttacaagtga
     5041 aaccattcaa aaaaatctct ctccgctttt atttgatgaa gataaagaag atgagatggc
     5101 gaggagattt gatttgtggt tgcttcatat tcagttgggg caactgacag ctaaatcttc
     5161 cactgttcat atttcccaag tgatgaagac ggctagagct ctttctgcta ttggcaatat
     5221 cccgcaggtt tttgagcagg ctgaaattat caggaaagta caggagcctg aattttggaa
     5281 agaagttaac ttgtctgatt tggaaaaaat tcgtcttgct attcgagatt tattacagtt
     5341 tttggataaa acagaccgta aaccctacta tgttaacttt gaagatcgta tactctccac
     5401 tgttcacgag accacagcat ttttgcaggt caacgatctt cggtcttaca atgaaaaagt
     5461 tgagcattat ttgaaaactc atctggatga ggagtccatt tctaagctat accataataa
     5521 aaagttgaca tctgatgata tgcttgcact tgaaaaattg ctttgggaaa aattaggtag
     5581 taaagcagac taccaaagtc attatgaaaa taaggcaatt ccgagattgg ttcgtgagat
     5641 tattggctta gatagagagt ctgccaatcg tattttttct aaatttttgt cggatgagaa
     5701 tcttaatgcc aggcagattt catttgtaaa attgattgta gactacattg tagaaaatgg
     5761 ttttttagag acgaaagtgt taacgcaaga gccgtttaaa tcttatggtt ctgttcaact
     5821 actcttccaa caccaactac cagtacttcg taatattgtt caaatcattg aacttatcaa
     5881 taatcgagct ggagaagcgg cttaaattct aaagtgattg ccatgctgag actcatttaa
     5941 aattaaaaag agtagaaatt tatgctatat atgagaagtt ttattaggaa gaatgtcatc
     6001 gttttcctag aatacagtat cagttgttaa gtggctgata aatttcaaag tagatacttg
     6061 taccacgatg tttgttgata gagttattaa caaaagagct actttgattt taaagaaata
     6121 gaaaacaaaa agccgagcaa gaattcaatt gcaggagaaa atgaaataat actcaatgaa
     6181 aatcaaagag caaactagga aactagctgc aggctgctca aaacactgtt ttgaggttgt
     6241 agataagact gacgaagtca gctcaaaaca tggttttgag gttgtagatg aaactgacga
     6301 agtcagtaac catacctacg gcaaggcgac gttgacgcgg attgaagaga ttttcgaaga
     6361 gtataaatct tcctaggata aagcaaaacg catagtatca agggttttca acacttgata
     6421 ctatgcgttt tctgatgtta aagactttct accagttttt tttaagcata attgttagtt
     6481 gtagtcattt attattcttc aaagaaaaat ggtggggcga attttttcag ttcttcaaag
     6541 cacttttgag cagtatctgc atcttcacag atgataagac agacatcatt accacaaagg
     6601 gtagcgatag cgtcagggaa gctcaaagta tcaatgatag aaccaaagga ttgagccagt
     6661 ccaggaaggg tttttagtag gacttggtgt tgaactgggc gcatccagac aagggcgtct
     6721 tccatgtaga gttcgagacg tttttcccat tttgagatgg aaccattgtt aagaacataa
     6781 taagcgctat cttcttcgcg gacttttgat aggttcatat ttttgatgtc gcgtgagagg
     6841 gttgcctggg ttacttgaat gtcgttctta gcaagaaggg cttgcaactc agcctgtgta
     6901 tgaatcttgt tttttgtgat aagagcgcgt ataagttggt ggcggtgttc tgatttattc
     6961 ataataatgt aactcctttt agcaaggtaa ggtaagcatg gactgagcga ggtcgacagt
     7021 caagtggtag tctgtattgt cacggatggt gatttcaaag tcagtagtat agaggactaa
     7081 acggagagtg tctccttctt ttagcttgta aatagttggc tgcagttcaa attgaacatc
     7141 catccattca tctgcagtaa tatcctctac taacagtaaa tcatttctat tttgtaaatt
     7201 aaggtaacct tttgtcacga ctcgttgtgc ctctggtcta aatggcaatt cacagagatt
     7261 ttccaacatg tgatagcgac cgttgtcaat ggttctagca cttaaaatag ctggataagg
     7321 ttgtaggtat ttcttttgcc caaattctag cagttgggca gataagagcc ccttgtttgt
     7381 actggatttg atacgaagat tgagctgagc gcgaccgttt aggtggagat ctttagtcac
     7441 aggaaggtta atagtaatct gattagcttt cccttgatag agctctgtat tgaaggtttg
     7501 gtatgtctta ctatagcgct caaaatcctt atctgggtac tggttttgaa tagcttgctc
     7561 ttcttgacca agtgagaagg ttttacagtt ttcttgccca ccgaagttat caagtgataa
     7621 ccaagtctgt ggagctgtat tgtcctgcca gataacagta ggaagttgaa agtctgtttc
     7681 ctgtcctagt aatttcttgg ttaataaggc atttatggac tcacggaagt caattgattg
     7741 ccaattgttc atgtaaacat gggcaccatt atggaaaaag agatgcttgt gtatatgagt
     7801 aggaagagca tggaacatct ggtaaacatg aagtggtttg acattccaat cctgagaacc
     7861 atgagtaaag acaacctctg cctttacttt atgggcattg agcagataat tgcggtcatg
     7921 ccaaaactga ttgtagtccc cagtttttcg gtctagctga gctttcactt tttctaagtc
     7981 agcttggtga gcttcattgc cacggatata gtcgccagct aagagattac gagaataggt
     8041 taactcagca agggagtcaa agtcctcacc tggataacca cctgggctag tcaccagacc
     8101 gttttcacgg tagtagttgt accatgatga aattcctgcc tcggcaatga taacttctaa
     8161 accatcgact cctgtagtcg caagaccatt ggacatggta cctagatagg aaagtcccgt
     8221 tgtagcaact tttccgtttg accaatcagc cttgacttga cgctggcgcg tgtgatcagt
     8281 aaaggcacgg caacggccgt taagccaatc gatgacattt ttataagcct cgatttgctg
     8341 gtagtctcca ttagtcatga aacctgtcga gtctttggta ccaacacctg agacatagag
     8401 attggcaaag cctctcggaa ggaagtagtc gtttagtgta tagctagagt tgatgtgagt
     8461 tagcttttcc tcagcctctg ctacaagctc agcttgacct tggggttgga cgagatttag
     8521 ttgaggttcc tctagctcaa tcttgtgagg aagcttaacc tcaagctcaa cctccatctt
     8581 gtagagagcc ttgtcactag ccttgtcatt ggttccctga tgataagggc tggctgtcat
     8641 gatggcaggg atttttccat caaaacgagg gcgaataatg ctaaccttta ctaggtctga
     8701 tagccctttt tggtcagtat cgacacgaga ctcaacgtaa acgacttcac gaatgacatc
     8761 ctggttagaa aaagtagcca aactcttgcc gttaaagtag tggtagtcat tatcctccgg
     8821 aataagacca tcactaacaa gttggtcgat aagagtattt ccttttttgg tgcgagtatt
     8881 gagtaactga tagagatttt caatcaagtc accatatata atgggaaatc cagtttcttt
     8941 acgaaaaacg tcactatctt cgaagtcaac caaataagca aagcctaaaa gttgaaaagc
     9001 aacagtataa aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg tcagcaggtc
     9061 tgttttttta tcagctgcta ggatagaaag tgggtagttg gtgtcttgat aagtgaaaaa
     9121 gaaacgacgt aaaaaggttt caagtgagtc tttgtgattg gctgtatttt gtaaatcaaa
     9181 gccacatttt tttagttcag ataagacatt ttcttttgga aaattgatat aactatattg
     9241 attaaaacgc atagaacctc catatagaat gacagttaag gttattatat caaaaaaaaa
     9301 gcagaaaggg aattgttaac ttcaaaagga aataatccaa taaaaatgaa taaagtacta
     9361 aattcaatat agagaacaga gtaacaataa gaataaaata gatagggtat
//
LOCUS       DAVHSH010000069         9305 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000069 DAVHSH010000000
VERSION     DAVHSH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.070"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     misc_binding    complement(94..311)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(394..3090)
                     /gene="ppc"
                     /locus_tag="VVR08_001864"
     CDS             complement(394..3090)
                     /gene="ppc"
                     /locus_tag="VVR08_001864"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU6075717.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(3110..4339)
                     /locus_tag="VVR08_001865"
     CDS             complement(3110..4339)
                     /locus_tag="VVR08_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6075718.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(4495..4797)
                     /locus_tag="VVR08_001866"
                     /pseudo
     CDS             complement(4495..4797)
                     /locus_tag="VVR08_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(5245..5466)
                     /locus_tag="VVR08_001867"
     CDS             complement(5245..5466)
                     /locus_tag="VVR08_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075719.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(6146..7357)
                     /locus_tag="VVR08_001868"
                     /pseudo
     CDS             complement(6146..7357)
                     /locus_tag="VVR08_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(7359..8603)
                     /locus_tag="VVR08_001869"
     CDS             complement(7359..8603)
                     /locus_tag="VVR08_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HEU6075720.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(8627..>9305)
                     /gene="galE"
                     /locus_tag="VVR08_001870"
     CDS             complement(8627..>9305)
                     /gene="galE"
                     /locus_tag="VVR08_001870"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6075721.1"
                     /translation="KVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEVL
                     LNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLNI
                     FGVDYSTPDGTCIRDYVHVNDLAYGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEIL
                     HSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQK
                     HPNGYDD"
BASE COUNT         3071 a         1822 c         1418 g         2994 t
ORIGIN      
        1 tcctttaaca tatttcactt atctaaacaa gcgacgccat tgttttcttt ccatactaac
       61 ctccatcaaa aaaatcctca cacaaaaaac ttgtgtgagg acgtcgatgc gcggtaccac
      121 ctcaattata gggaatttcc ctatcgctca gtctcgcaat aacgagatgc actgtaaggt
      181 gtgcttaccg aatttttata atttcaaatt ctaaatagca ttcagcccaa ttttcatcat
      241 tgccacttat ctgttttcag ctaccacaga ctctctaaaa agtttgtatg attacttttc
      301 tgaatggtta aattatatca tttttaaact acttgtcaat agtctattag aatttttttg
      361 atattcactt ttagcattca ctcttgaaaa ttatcaacct gaattacgca atcctgtcgc
      421 aattccgttg atggtgatat gaatcaatcg ttcttgatca ctggacaatt ctccacgacg
      481 ttggcgttta atcaactcca actgaatata gttgagaata ttaaagtaag gcatacggta
      541 atccagacta gcttttagat atggattgtc agctaagagt tcgtcatgtc cttcaatagc
      601 caagataacg ttcttagtaa cttgccattc atttaaaata gtctcataga tggccttaac
      661 ttgctcgtct tcacaaagtt tagcatattc aaaagcaata ttcatatttg attttgacaa
      721 aaccatatca acatttgaaa gaagcgattg gaagaaaggc caattttggt acatatctcg
      781 taagatagca atattctctg gatttttatt gataaattcc ttgaagcttg aaccaacccc
      841 gtaccatcca gggaacataa cacgactctg tgaccatgag aatacccaag ggatggcacg
      901 caatccaccg atttcagtaa tagtcttacg agcggctgga cgagaaccaa tattaaaact
      961 tgaaatagcc ttgattggac ttgactcgaa gaaataatca tagaaatgct cattaccaaa
     1021 gaccaaatca cggtagatat cgtaactacg gtccactact tgatccataa tggcttcata
     1081 acgatttggg gtattggtat cgctcttctt ctgagtaatc atacggttaa tagctgccga
     1141 tactagcatt tcaaggttat agtaagcggc gtctttgtta ccgtatttat tcccaattac
     1201 ttcaccctgc tccgtcaagc ggatacgatc cttgatagac ttgagcggtt gagatgtaat
     1261 ggcttcatag gttggcccac caccacgacc gacagtacca ccacgaccat ggaagaaggt
     1321 aaccttaacg ccaaattcat ctccaatagc agtcaattgt tgttgagcct tgtagagggt
     1381 ccaacatgat gacaagtaac cgccatcttt attactgtca gagtagccaa gcatgatttc
     1441 ttggtagtta tttcgtgagt caatccattt tttggcaagg ctaagagaaa gatattttct
     1501 cattgtttcc tctgaatgat ccaagtcttc aattgtttca aaaaggggaa caatctgaac
     1561 acgcgccctt tccgtatcca ccagtcctac ttcttttaac agaatagcta attctagcat
     1621 atcagaaaga ctggttgcat gtgaaatgat ggtctgacgg atgacatcat ctcccaactt
     1681 atctttcaaa acacgagccg tcttaaaaat agctaattct tttgctaata attctgattt
     1741 ttctgcgtga gtcgcagaaa gaattcgggg atcttcttct aattctttca agagaaggtc
     1801 acacttttct tcttcgctca actcgctata acgagaatga attcctgctg atttcaagag
     1861 ttctgccaca caggcttcat agacgctaga gtcttgtcgc atatcaattg acgctaagta
     1921 aaaaccaaat atctctactg cctgcaataa ttccacaaaa tcacctgaaa tcaaggactc
     1981 acccttattt tctagtagag aatctcgaat ggcaatcaaa tccttgtaga aatcattggc
     2041 ggtttcataa cgagtcccaa cttcttcatc ctcaatcaga taggttttag ttgcctgaat
     2101 ttttgattga atatcaaaca aggcacgacg gtaaagctct ttttcgcggt aaatagagtt
     2161 atccttggat tgacgagcca tttctctgac ttgcttgctg acgttgacaa tgctagttga
     2221 aagagaaaat tcacgataaa gttggtaaat ctttttatca tagtagttca tgatgacttc
     2281 acactgagtg agtgcagact gcttcaaggt ctttgctgta acaaatggat ttccatcacg
     2341 gtcaccacct atccacatac ccatggtgat tggtttagcc tgttttaaat tcagaccatg
     2401 cgcttgcgct aagcgcttat actccgtcgt caaatgaggg acagctttca aaaaggagct
     2461 gttgtaatat tccatagcat tcgtgatttc gttagtcact tttaattttt tctcacgaat
     2521 catgtctgtc tgcatgataa tttcgatgta acgacgcaaa tcattgtgcc atttatcttt
     2581 attgattaac cccaacttaa catcacggta tttacgcaaa agactatgaa tatgatttgt
     2641 taaatccaac atacttttgc gttgcacttg tgttggatgg gctgtcaaaa cagggacaac
     2701 attcaagtgt tctaggatct caacggcatt ttccttttct gctaccaatt taatcgttgt
     2761 agataattta cctaaatagt cctgatcaat attattttga tgattgattt cataagctaa
     2821 atccacatcc tctgaaatat taatcaaaag aggtaagata gagaaatagc gtgaaatata
     2881 gaccatttca tcatttgata agctagtcac tagacggttt agaccttgat aatcttcctg
     2941 cgttgataat tctttcaact gtattatttt ttcaaaggtc tctggggcaa gcatattttt
     3001 agtaatatct tccagtaatt ctgttagaat caagacttct tctttcacaa cacttttatt
     3061 actataattt tctaattttt gaagagacat aaactatcct ttctttatcc tacttcaaca
     3121 gaaggttcat tggttgattt tccaattctc ggtacaactt agcgcgtttt tcactggcat
     3181 caatatttaa gacaaaggct actgccactg ataagactag aagactattt ccaccctggg
     3241 ataagaaggg gaaagtcact cctgtagatg gaatcaagcc cgaaatccct ccgatattga
     3301 caaatacctg aaccaacatc atccctccga caccgagtgc aaccatggca ttgaaaggat
     3361 tctccgctcg gataccgacc aagataatcc gcaaaatcat gaaaaacaag agagctaaaa
     3421 taagactggc accaacaaag ccaaattctt caatcacgat agaaaagaca aagtctgtat
     3481 gagcttctgg caaataacct cgtttttcaa tcgagtttcc aagacctaga ccaaaccaac
     3541 cgccattgac catggcaaaa taagaattag ctaactggtg acctgcatca gcacgatcgg
     3601 caaaaggatt aaaaaaggca ctaaagcgct tggctacata gccaaatact ggaatttttg
     3661 aaaaggtctc aacaccgatt aggctgatag tggtcaagac aaagacagaa gtggcagata
     3721 cgagcgccag aatggttgaa aaccagcgat aagcgattcc actaactgta tacataatca
     3781 aggaaaccaa gactaaaata gtcgcatttc ctaaatcagg gaaaattccc aaacttccaa
     3841 tcagaactag gagaacgaat cgccaatcat taaaagcacg gggaagccat tgattttgag
     3901 tcaaaacttg aaaatcataa gtagctattt cttcttgctg tttggagaat cggtgagcta
     3961 aataccaaat aataatgatt tttaagtact cagctggctg aatagttact cctgcaaccg
     4021 aaatccaacc gtatgccccg tttacggaaa taccaataaa acgagccaag aacaataaaa
     4081 gcatttctat taatataact aaaatgatta gtcgctcatt tctcaaaaaa tctagtctca
     4141 atttataaat taaggcaatc agtatcaaac taacaatcca aaagattcct tggtttcgaa
     4201 ccaactgcaa ggcactcttg ccttcttcaa ttaaaatagc actggtggtc gaatagacca
     4261 caatcaagcc caaaatagat aaaagcaagt agggaatcaa gatggaataa tttaataagt
     4321 gcctcttact aatcttcata gcatcaccac tctactagga tacagataaa tctgttccaa
     4381 attccgtttt attttctagt tttgattgct attataccat tttttcagaa agaaaaaaac
     4441 tcttacctta caatccttcg aattttactg tttttacaga attaaggcag aatttgaaat
     4501 cgtaaaacca ttttgaataa gagttgcttc aacccattga ctccgacgga ttaagttgct
     4561 ttcgtgaatg ccaaaatcag ccgcaatttg ttcataagtg ctctattctc gcatgtattg
     4621 aatagttacc ataaggagat cgtctaggct taatttgctt tttcgtccac cttttgcgcg
     4681 tttacgttga taagctgttt ttaacacagc taacatctct tcaaaagtcg tgcgctgaac
     4741 acctacaagg atcttgaaac ggctatcgct taattgttta cttgcttcat catccatagt
     4801 tttattgtat tgtatttttg tttcgcagga agtctattat tcctttcgtt ccaaggtttt
     4861 tacgcttttt caagcaatcc tacacactcc acgtgatgcg tctgtggaac tcaaaaggtt
     4921 cggggaacct tttgaggatt aattgcgttt ctctaacaaa ctcacacatt caacgtggca
     4981 tgactgatga agtcatcata agaatttcac ttgctgctct ttctcggtgg cagcctgaac
     5041 ggtcagaagt atcattgtat atcatttgta tcatggcata taaagtatcg ctctatttta
     5101 ttgatggttt taatatcgct cttatcatgg cgaaccattc aaatctgctc cacaaatgag
     5161 gaaagtacca ttttggacta ttcaattgtc aaagaacaaa taaaaaaaat cttcgcattt
     5221 tcacactcta tgaaattgag gagattattt tctaaagcga attttatcag gaaaatccgt
     5281 caatcccaat aggtagtctg tactgacatc gtaaaagttt gagagagtta ccaatatatc
     5341 tgctgttaac gtatgctcac cccgttcaat tttagcataa gctgagtctg taaacgaaag
     5401 tattttagct atttgttttt gggtcaaatc gtgatcttcc ctcaaatctc tcaaacgtct
     5461 gtacatctag ctttctcctg agaaaagtat aatatataaa actaagaaat cattcaaagt
     5521 gtccaaactg gacattttga actaaaatta atttattaaa catatctcat aagcatatct
     5581 attataggta agacaatatt aagaaagacg gtcaaaatct attaaccgtc taaagatgtt
     5641 ataagctatt aaaaaatcag cagtaatccg gtaacaaaag tcacataatt ttgttaagga
     5701 agggattaat gatgtccaga ttactactaa ccagcaaatt gaaaaatggt caacatgata
     5761 tttctaatgt gaatctctta ctttcagaac ctaaaagttg aataatagcc accccctact
     5821 tatcaataaa attttccgtt gcattaacag atgtatatag accactccat ggatttcaaa
     5881 gcaattaact agactttatt tgtcaataac cacaaaatta gattagaaaa atcattaaaa
     5941 attaattgga gtcctttgtg atgctttttc aataaaagta atacttctca atattttaac
     6001 tgaactaaag aaatagcata atggtatctt gattgtattc ttctaaaaag gattgccctt
     6061 cacattcaac tgtgattgat taaattccaa aaatatattc caaaggcgct ctaaattctc
     6121 tatatcagct attttttatc atctatcaac ttctatcata cctcttcaat agcgtgctaa
     6181 atattagcga taatatcgta atagatacac caataataaa aaaattaaaa gtattgttag
     6241 gatttaaaac tactgagaaa aaaacagtac ctagtggcat aaaaagaata gctaccgtaa
     6301 agatgattcc aaatactctg ccaagaaact cattatctac gtctctttga acaatagaga
     6361 aaaattggat attaaaaatg gaaagaaata gactaaataa tgctggagta aaggctaaaa
     6421 taatgacgtt gcggaacata taatagatcg gcgctgttag cattaacatc aaacctgaat
     6481 atgctaaaaa gagcattaaa cgtttgcttg acaaggattt attgataaat ccacttaata
     6541 tcgcaccaat aaagccacca atcgcttcgg ctgttaaaaa ggttccatat agcccacttg
     6601 aaatacttcc aaacatttga ttactgtatg gcagcaacaa attataggct gctaggaaaa
     6661 agttaacaag tgctgaaagg gcaattatag tgagaatttg tttatgacta tatacatacg
     6721 taaatcctat ttttaaatca tcaaagattc ctcttatcgt catattctct tttgtatcca
     6781 cctcctcatt tacaggagta atgaagaaaa ttagtgaggc agcaattaaa aacgataatc
     6841 catctagtaa taacacacca tgtattccaa gtaacttata taagaaaatt gcaatcatag
     6901 gaattgttac tttaatcaca gtacttgttg tttctagcaa tgaattaagt tatgatatac
     6961 tgtccttttt tacaatttct ttcgtaaaag ctttgtatga tggccctgaa aaagcactca
     7021 taaaagccaa aatgacattt gttatgacta tcgcataaac caaccatttt tcttgggata
     7081 taaatgaaag agttatgcaa gcaataccac ataagatatt tgtagtaata ataatttttt
     7141 tccgcttgaa actatctgca ataactccac caaataaatt aaatagaaca cctatcatac
     7201 tttctaatga ttgataaatt gcaaccactg atagagatgt tggattaaga ccagcaagaa
     7261 aggtattatt ggcgaaatca aacatgatat ctccgattcg agatatcatc ctactagcta
     7321 caatggatag aatattgtga tgttcttctc taatcatttt attctcccga atcagtaatc
     7381 acatatttaa acttttgtga tatgtgctta agttcatcta accttttctc aaattcacaa
     7441 ctatttttgc aattaaattg gaccaacatt gaattttcga ctacattttc agatacttta
     7501 tagtaagtat ttggtttaat aaatatgtac actttttttg cccaagccaa ttctttttca
     7561 tcaggtacct cgataacctt accttgcttt ctatataaag caaacgttgc tgagatatta
     7621 gcaggtctag aaatcacttt agaaaaattt atttttttca atccttgtga attagtcaaa
     7681 atatcccaat attctttaat tacatcaact ccatgactat cctcaattaa ctggggaata
     7741 tctccccctc caaatctttt tccaacttca caaaagacta ttttaccagt tgataattca
     7801 aggaaccatt caaaatgaaa aggggttatt tcagaattga tagaaaaaac attcaaaact
     7861 ttgcgacatt cttccaatgc tttttctatg tattcaattt tttcactatc attatataac
     7921 gaactagtcc ttacaagata atatccacta gaacttaagg tattgaacaa tagttcctca
     7981 tattcgtgaa cataaaatcg cttaatctca cttccaattg aataaccatc acatgttatc
     8041 atgttatcga tatcaatgta ttcctctata atatagtttt tttcaaaata cactgaatca
     8101 attttctcgt tagggtaaac tttttttatt ccattacttc ctgcttcatt tctaggtttt
     8161 aaaattgcag cagaagattt acaattattc caaaaaacac gtaaatcatt ttctgattct
     8221 aaaagcctaa aatacggttg atttactact ccaactaaaa atgaacgcat gaagtatttg
     8281 tctttaaata ataaattaga cacagagtga gtattttttt ctacaaaatg atcattcaaa
     8341 aaacctacta tatccatgtc ttcctcactc aaggttgtaa tactctcaac ttctgtattt
     8401 tgacttatcc ttctaatttc taagatgata tttggtagaa taaaatcttc taaaaaaatg
     8461 accttaggta gattatttcc ttcagctaga taatcttcat atttttttct ttgaacctca
     8521 ggtgcaataa ttactacatt tctgttatac agatatttta gtttaacaac ccgtgcagaa
     8581 tatctaaata atactatatg catgttaatc ccaatccttt caattattag tcatcatatc
     8641 catttggatg tttctgttgc catttccacg tatcttggca cattttcata atatcatacc
     8701 ttggcttcca tcccagtagc tcttctgctt ttgaaatatc tgcaattgaa acgtccatat
     8761 ctcctgctct ccttgaagtt atcttatatg gaatatacga gcctatgaca ctctctaagc
     8821 tgtgtaggat ttcaaataca ctaaaaccaa caccacttcc taaattgatt acttcatata
     8881 aaccttcatc tgtattaaaa atatactcta atgcttttct gtgtccgtat gctaaatcgt
     8941 taacgtgaac atagtccctt atacaagtcc catcaggagt actgtaatca actccgaata
     9001 tatttaaata tggtaatttt ccaattgcaa cttgtgtaat gtaaggaaca agattattcg
     9061 gaattccatt tggatcctct cctaaatcac cactttcatg tgcacccaat ggattaaaat
     9121 acctcagaca aacaattttc caatttgaat tcgaaataaa caaatcattt aaaagtactt
     9181 ctatatactg ttttgttctc ccatacgggt ttgaagcttt taatggatta gtctcataga
     9241 atggcatgat aggagtactt tcgtatacag tagctgatga actaaacaca aaattaaata
     9301 cctta
//
LOCUS       DAVHSH010000070         8441 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000070 DAVHSH010000000
VERSION     DAVHSH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8441
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.071"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(86..1282)
                     /locus_tag="VVR08_001871"
     CDS             complement(86..1282)
                     /locus_tag="VVR08_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU6075722.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINVLEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(1372..6351)
                     /locus_tag="VVR08_001872"
                     /pseudo
     CDS             complement(1372..6351)
                     /locus_tag="VVR08_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            6644..8275
                     /locus_tag="VVR08_001873"
     CDS             6644..8275
                     /locus_tag="VVR08_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU6075723.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGDLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIIQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT         2265 a         1863 c         1580 g         2733 t
ORIGIN      
        1 taatagttga gaggaagcgt ttttatttta agcaaaagaa aagaggaact ttcatccctc
       61 tcttctttga tttgtttata aaatcttatt tttctgtcaa ggctgcaagt cctggaagaa
      121 ccttaccttc aagaagttcc attgatgctc caccacccgt actaatccat gagaacttgt
      181 ctgcacggcc aaggttaatc gctgcggcag ctgagtcacc accaccgatg attgatttaa
      241 ctcctggttg tttcacgata gcgtccatca caccgattgt accagcttgg aaatctgggt
      301 tttcaaatac acccataggt ccgttccata caactgtttt ggcaccagtc aaagcttcgt
      361 caaatttggc gatagatttt ggaccgatgt caagaccaag gaagccttca gaaactgctt
      421 caccttcagt gtcacgcact tcagtgtaac cagcaaatgc gttagcttct tttgagtcaa
      481 ctggcaagat caatttacca tttgcttttt caagaagagc tttcgcaaca tccaatttgt
      541 cttcttctac aagtgagtta ccgatttcga taccttgtgc tttgtagaat gtgtaagtca
      601 tcccaccacc gataaggact ttatcagctt tttcaagcaa gttttcgata acaccgatct
      661 tgtctgaaac ttttgaacca ccaaggatag ccacgaatgg acgttctgga gtttcaactg
      721 cttcttggat ataggcaatt tcgttttcaa gaaggaaacc agcaactgct ttttcaacgt
      781 ttgctgagat accaacgtta gatgcgtgtg cacggtgagc tgtaccgaat gcatcgttta
      841 cgaagatacc atctccaagt gatgcccagt atttaccaag ttcaggatcg tttttagatt
      901 ctttcttgcc gtcaacatct tcgtaacgag tgttttcaac caagagaact tgtccatctt
      961 caagaacgtt gattgccgct tccaattcag caccacgagt gacacctggg aaaacaacat
     1021 cttgaccaag ttttgctgcc aagtcagctg ctacaggagc aagtgattta ccagctttat
     1081 cagcttcttc tttcacacgt ccaaggtgag agaaaagaat tgcacgtcca ccttgttcga
     1141 tgatgtactt aatagttgga agagctgctg tgatacggtt atcgttagtg attacgccat
     1201 ctttcaatgg tacgttgaag tcaacacgaa cgaggacttt tttacctttc aagtcaacgt
     1261 ctttaacagt aagttttgcc atgttacaaa aactccttta tttattttat tcgaaactat
     1321 tatatcacac tttggaaata taaggaaaga tttcacaaga tttttcgata tttaatcttt
     1381 atcttctctt ttccgtctca aggtcaaggc taaactagca agaccaaggc tggctaagcc
     1441 tgctattagg gcttcattag catcagctgt tcctgtattt ggcaattgtt tgcttgcttc
     1501 ttctgattta actgctgtat tttgagctgg tttttcctgt gtagctacta ctgctggtac
     1561 tgtttttact tttgttccaa tttcaacaat ttctggaatc gcttcttgga tgacttctgt
     1621 tgaacgaaga cgacgctgac cgttttcatc aacttcaaag acatgtctta acagtccatc
     1681 tcgtccctgt atgatgactc gttgttcccc aactagcatc tcagcatttt catgctcttg
     1741 acgatgaaag gcaacctttt cctcttgaac ttccaattta ggagcctttt gttgatcaga
     1801 agccggttga taagtaggtt ttggaaggac tgtgttttgt ggtgctggtt tagcaggttg
     1861 tggtttttca gcagattcat aaacaaaggc ataatgagta aagtgaggtg ctgtaaagat
     1921 aacatgacta tccgtttgtt caaaagccaa ttctactgcc tctttgcctt caggtaagaa
     1981 aaatactttc ttaactttct tatctttttc aattgggatt ttcacaatag aagcgtaaga
     2041 gagatcaaca tcttgacctt tttcatccaa accttctatt tcaaagacat gagcatcttc
     2101 tccagcaaag tatttcttct cttcagcact tgcttgaaca cgctctactt tcaaaccctt
     2161 gatgacagtc ttctctttat ttgagaagtg tacttcaaca cctgttttac tatcagaaaa
     2221 gactgctggc ttgtcttctt tcaataaagc aaccagatct tttagactct gtttcgctgt
     2281 tgtaagctct tctggactca aatctacttt ttcaaccaag gccttgtttt tctcaagaag
     2341 cggagctagg gcagaacctg aaggatggtt tggtttggca gccaagagtt cttgaacctc
     2401 acctgttaag cgatcaagtt ctgtcttttc ttccttaaat ttctcttgac cattcagagc
     2461 tttatgagcc tctgtcaatt tattaagtcg gtcattgact tgatcttggg tgctagtttc
     2521 atggtctttc aacacttgtt cggccgcttc aattgctttc aagaaagctt cttttacttc
     2581 tggtgaagca aagttataga ccaccttgtt cttagcagct tcaacttctg ctaatttttg
     2641 tttgaggtac tcatcgttca atgctgcttt tggagatacc aaaacatcaa agctaacttc
     2701 atggccttgg taatgaagcg tcaaggtttg acgaccagtc ttttgagcat cgtaaccaga
     2761 aatttcaact ccctcatcag taaaggaatg ttattccatg gtgtcattgc tataagccac
     2821 tgcaaagcgt ccttcagaca agtctaagct atcaccaact aggtaatctt ttttcggttc
     2881 ctgacttact tcaattccca aaatagtttt cggacttgct tcgtctttgc cagtgacagt
     2941 cactgacaaa ttagcattta ccggttgtcc caaatattgg agagtaagat tctgttctcc
     3001 cttatgatgc gtatcaaaac ctgatactga tacacctgcg tgagttaggc gaatgagttc
     3061 gtcctcagtt cctccttcat actgaactcg aagaacacca cctctaaggt ccaaatcctc
     3121 cccttcggcg tagcttgttt tcttaggtcc tgtttctagg ctgactgact tgattcttct
     3181 gtcatctttt ggaacggaaa ctgctaggac attactaatt tccttgcctg gcaactgggt
     3241 acgataataa agaagaccag attgatttgt caaatccaat ggtgcacttg ctaggtctcc
     3301 tccaacttcg ctcttcaagg ttgcaagcgg agtttgagaa tttggattat cataaacagt
     3361 aatagttgct ccagccggta catctgaaaa gccaacttgt accttgttat tgcctagaga
     3421 acgggctgca gccttggcca tcggaatatt gacactctca gtatcaagct tttcatacat
     3481 tttccagtta tagatacgaa tagccttcca tggagttcca ttgtcagaag tgacaacatt
     3541 caagcgccag tcttgagcag tgattggttt atcaagagtg atatctgtca cgtgtgcttt
     3601 gttgccacgg acttccttag ctagcttcca ctcaccatct gcatctttat aataaaggtc
     3661 aaagtctttg gtgttcatca agccatcgtt aacagactca ccaccagccc ctgcatgatc
     3721 catgacccat ctaacaacgg tacgtggctt ggtcaaacga atatccacac taccactcaa
     3781 ctgagctgaa gaccatttat ctgacaagct agtaatggta ccgttcaaca taccttcaat
     3841 accttctcca ccttcagtct tagggaaagt actatcaata actgttgcac ctggaacgat
     3901 attttcagct agtggttttg gtaggctggt atcttttaca gtcatacccc aatcaaaggt
     3961 tgtggttgca gcttctgaac gaactccatt tttaccgact gctacaacct tcagttcttg
     4021 agttgtaccc tgagcacttg ctgagcggct aacttttggt agataaatag ttgtagaaga
     4081 tgagccagtt agtaatttcc agctgtctcc atctttttca taaacttcat agaaatctgc
     4141 atccttgttg cctttaaatt gcacaactgc ttccgcttct tgggcatttt taagagattg
     4201 tttcactaca gaaaagcttg tcggcgattg tggctcttgg tgattgtccg agatagttaa
     4261 ttgtccgagg ttgaactgat aatcttttac agcaccttca tgctcgaaaa atagtttaac
     4321 tgcatagatg gttttacctg ctagtgagct gagatcaaat tcttcatttg tccagttgtc
     4381 agaaagggtt agctctttcc atgcatctgc atcatcgaat ttgtagtctg aagttgtaga
     4441 gaatgccata taaactttag aaccttttcc tcccttgtgg gcaacacgaa gtttggtctt
     4501 ctcagttact tctaacttag tagaataaag tctcacatcc tgaactgtct taccggctac
     4561 atcaccagag aatttaaggg aatttccgcc attataggca tctgtaaaat catattctgc
     4621 acgaagtttt tcccctgttg aagtctgcca ccagcgccat gttggaagaa cacctgatac
     4681 tgaacgataa ttccactcag aatccttaga aaccttacca tctacgaacc attttttacc
     4741 atgacctgta ttaaaagaag tagtaaaagt attacctacc gctggcgtac ggtccgcaac
     4801 taggttagca ataccatacc aatctttgtc acctggtttt tggccagtgg ggtctccttg
     4861 ataacctgta aagaagatat cttcattttt atgataatct tcaccagttt ttcctaaact
     4921 tgtaatggta tctggggcaa ataaaccaag agaaaggcgc aatttcccat tttcgtctaa
     4981 aatgtcattc cacttaacct ttgtcttgta ggaaccaccc tgttgcaatt ccaaacctgc
     5041 aaatacatca taaggattac gaccaatcca gttggcagtt gcaatagtgt aatcattttt
     5101 agccttatcc cagttaaagt tagcaaagaa gttatctgcc ggaaccttat ctccttctgg
     5161 ttgcatgaat tggtagttgt attctcccaa accatcttga tggtaacgtc catagttata
     5221 ggtcatggca tcataccaag aatacttgat tggatggttt accttagcag catattcctt
     5281 gctatagagc ataaactggc gcatcttttc tccaagaggt ttaaccaaat ctccagttgt
     5341 ttcttggttg atgaaatagc catcatagcc ataatacttg gccatgtcta ccaatttacg
     5401 ggcaattggg aagctaccat ctgcgtcttg cttcaaagct tcagcaaatc tttcttgatc
     5461 tgcaatacta ttagaccagt tgaagaagag tgtaccgtat acaggaaccc cgttacggtg
     5521 acctgcatca ataacgtcag gagttggtac gagaccttcc cagaagacca ttgaatctag
     5581 atattgccaa tagtcaaaag cataggcctt gaactcttct ccaccaacag aagcatggtc
     5641 ttttgcttta gaattggtgt ttgataaggc ttgaactttt gcttccttgc tagctttttc
     5701 attgactaaa tgacctgtcc gacgtgaagc gaggacaaca gatccgcggt taatagcatc
     5761 atcttcacga gcacctggtt cccattttaa caattcttcc caagaattaa atttgatttc
     5821 ctttggtttt aatgtttttt ctgtattttt agggacatct ggctggactt ctttttcagt
     5881 cttattagct tctgctgctg gtttagactc atccccttgg ttagttgctt cgggctttgc
     5941 ttctgtttcc ttgtcagact taggttttgc ttctgcagat ggtgtttctg caaccacctc
     6001 acttgctttt tcctctggtt tagctgcgct agctgcttct gcagtttcag tagttgcagc
     6061 ttcattgctt gctggcgaag cagtttcaga tgctgtcgct actccttctg ccttttctag
     6121 cttgttttct ctagcatgtt ccccttcatt ctgcttatca gcttcattgg tcgaatgctc
     6181 actctctcct gaaacaagct ctgtattagc tccgctattt tcaggaactg cagtttcttc
     6241 agccaaggct ggaccagcaa ataaaacagc accaatcatc agcgagcagg ctcctactga
     6301 taacttacga atactgtaac gacaacgtct ttcaaaaaat ggattcttca ttttctcctc
     6361 ctaaaagatt gattttgttg ttttaaagaa agcgctttat attctgtagt tttttatcaa
     6421 actctagaac catgataatc acatttttat cctaaaacat ttttagacaa aaaacaataa
     6481 ctgtttgcac aaatctaaaa taaggttaaa aactcttaaa aataatacac ttatcaatta
     6541 taattttctt ttacaaactt gacattaaca cttgttagat ttacttttat cctttaaaat
     6601 agaataggag atattccgcg attatttttc ggaggaaaaa gaaatgtcca ttaattggca
     6661 agaaatttta tttcactttt taggtggtct ggggctattc ttatatagca tcaagaccat
     6721 gggagacggt ttgcaacaag ctgctggaga tcgccttcgt ttttacattg acaaatatac
     6781 tagtaatcct ttctttggag ttctggttgg tattgggatg actgctctaa ttcagtctag
     6841 ttctggtgta acagttatta cagtcggcct ggtcagtgcc ggtctcttaa ccttacgtca
     6901 ggctatcggg attgtcatgg gtgctaatat tgggacaact gtcacatcct ttctcatcgg
     6961 ttttaaatta ggtaactatg ccctacctat gctctttatc ggtgccgtct gtctcttttt
     7021 tacgaaaaat cggacagtca ataatatcgg acgcatcctc tttggtgtcg gtggtatctt
     7081 ttttgccctc aatctcatga gcggcgcaat ggctccactc aaggatttac aggtctttaa
     7141 ggactatatg attgagctaa gtaagaatcc tgttctgggt gtctttgtcg gtactggctt
     7201 gaccttgcta attcaagctt cttcggctac cattgggatt ttacaaaacc tctacgccgg
     7261 cgatctaatt gacctacagg gagctttgcc agttctattt ggtgacaata tcgggacaac
     7321 cattacagcc atcattgcct ctttaggggc taatattgca gctaaacggg tagcaggagc
     7381 tcatgttgcc ttcaacgtta tcggaacagt cgtctgcgtt atttttctag ttccttttac
     7441 tgtcctgatt cattggtttg aagctacgct aaatctagca ccggaaatga ccatcgcctt
     7501 tgctcacgga acctttaata ttaccaacac cattatccaa tttccattta tcggagctct
     7561 ggcttacttt gtaaccaaga ttattcctgg agaggacgag gttgtcaaat acgaaccctt
     7621 atatcttgat gaacatttca tcaaacaagc cccatctatc gctctaggaa atgccaaaaa
     7681 agagctcttg cacttaggaa actacgctgc taaagccttt gacctttcct ataagtacat
     7741 cattgacttg gatgaaaaag ttgctgaaaa agggcataaa accgaagaag caattaacac
     7801 catcgatgag caattaacac gttatctcat tgccctttca agcgaagctc tcagccaaaa
     7861 agaaagtgaa gtgcttacca atatccttga ttcctcccgt gatttggaac ggattggaga
     7921 ccacacggag gctctactca atctgactga ctatcttcaa cggaaaaatg ttgaattttc
     7981 tgatgccgcc ttgaaagaat tagaggaagt ttaccgccaa actagtgact ttatcaaaga
     8041 tgctctggat agtgtggaaa acaatgatat tgaaaaagca cgcagtcttg tagaacgtca
     8101 tgaagcaatc aataagatag aacgtgttct cagaaaaacc cacatcaaac gcctcaacaa
     8161 aggcgaatgt tcaacacaag ctggggtcaa ctttatcgac atcatctcac actacactcg
     8221 tgtatcagac cacgctatga accttgctga aaaggttttt gcagaacaaa tctaataacc
     8281 aagaagctat ccatcataat tggatggctt cttacttttt cctaagcaag actaggctga
     8341 atgaaactga aagagtattc tgcagatata tagtatattg aaactagaat agtacacctc
     8401 tatttctaaa acattgttag aaatcgattt gactgtcctg a
//
LOCUS       DAVHSH010000071         8402 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.072, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000071 DAVHSH010000000
VERSION     DAVHSH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.072"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..749)
                     /locus_tag="VVR08_001874"
     CDS             complement(join(<1..379,381..749))
                     /locus_tag="VVR08_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU6075724.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIRQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTIEDKVYNHA
                     LSKERSKVENIFAKVKTFKMISTTYRNHLNA"
     gene            complement(842..1000)
                     /locus_tag="VVR08_001875"
     CDS             complement(842..1000)
                     /locus_tag="VVR08_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU6075725.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(1071..1500)
                     /locus_tag="VVR08_001876"
                     /pseudo
     CDS             complement(1071..1500)
                     /locus_tag="VVR08_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1595..2035)
                     /locus_tag="VVR08_001877"
     CDS             complement(1595..2035)
                     /locus_tag="VVR08_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075726.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            2026..2334
                     /locus_tag="VVR08_001878"
                     /pseudo
     CDS             2026..2334
                     /locus_tag="VVR08_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2489..2812)
                     /gene="tnpB"
                     /locus_tag="VVR08_001879"
     CDS             complement(2489..2812)
                     /gene="tnpB"
                     /locus_tag="VVR08_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6075727.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(2793..2978)
                     /locus_tag="VVR08_001880"
     CDS             complement(2793..2978)
                     /locus_tag="VVR08_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075728.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(3251..3862)
                     /locus_tag="VVR08_001881"
     CDS             complement(3251..3862)
                     /locus_tag="VVR08_001881"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEU6075729.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(3885..5270)
                     /locus_tag="VVR08_001882"
     CDS             complement(3885..5270)
                     /locus_tag="VVR08_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEU6075730.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            complement(5271..7046)
                     /locus_tag="VVR08_001883"
     CDS             complement(5271..7046)
                     /locus_tag="VVR08_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEU6075731.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            complement(7109..7429)
                     /locus_tag="VVR08_001884"
     CDS             complement(7109..7429)
                     /locus_tag="VVR08_001884"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEU6075732.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            complement(7419..8366)
                     /locus_tag="VVR08_001885"
     CDS             complement(7419..8366)
                     /locus_tag="VVR08_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEU6075733.1"
                     /translation="MTEEKFQKIIQSKDTETLAFILESTPYHLSIDILEDPSQTEISL
                     MTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLKSKAAIKKDFSKLLIPIGIFD
                     IESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNE
                     LDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLLSDEGSISAKEFIYIVENQEI
                     FVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRYNVEGPLVLA
                     RYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYGS"
BASE COUNT         2625 a         1722 c         1333 g         2722 t
ORIGIN      
        1 aagcgtttag atgatttcga taggttgttg aaatcatttt aaacgttttt actttggcaa
       61 agatgttctc aaccttgctt ctctccttag atagcgcatg gttatagact ttatcttcaa
      121 ttgttagcgg tttgagtttg ctggatttac gtgaagtttg tgcttgagga tatatcttca
      181 tgagcccttg ataaccactg tcagccaaga ttttaccagc ttgtctgata tttctgcgac
      241 tcattttgaa caacttcata tcatgacaat agttcacagt gatatccaaa gaaacaattc
      301 tcccttgact tgtgacaatc gcttgagcct tcatagcgtg aaatttcttt ttaccagaat
      361 aattcgctaa ttcttttttt agggcgattg atttttactt ccgtcgcatc aatcattacc
      421 gtgtcctcag aactgagagg agttcttgaa atcgtaacac cactttgaac aagagttact
      481 tcaacccatt ggctccgacg gattaagttg ctttcgtgaa taccaaaaac agccgcaatt
      541 tgttcataag ttcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctaga
      601 cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt ttttaataca
      661 gctaacatct cttcaaaagt cgtgcgttga acaccaacaa gacgcttaaa tcgtgcatcg
      721 gttagttgtt tacttgcttc atcattcata gaactattat accatatttt gtttcgcagg
      781 aagtctattg aaaaatctcc agactggaga actcacggat agttcctaat ctggagattt
      841 cttatttgca cttttcttgt acaactttag tccatggtaa ataagcctct aaaacctctt
      901 tgtttacgag agtttcctcg tttggaagac attctagaag ataggataga tatttctcgc
      961 tatttaattg atgacgttta gctgtttcca acaaactcat aataatagct cttgctttag
     1021 ctccttcaaa actttgagaa aataaccacc ctcgcttttt taaactgagc ttaggctaaa
     1081 agagtccact ggactctttt actccgtccc ataaccaatg atttaatggc gcgttcagct
     1141 agattattgg aaaggaccag atgtccgtct ttcaaaatgg tcttaaaggt ttcttcatac
     1201 ttgaggctgt attcaattgc ccttcctagt tttgaacctg ctaaaactga ctgacgccgg
     1261 cactaagcaa agaagtcttc cattaagggc tggagatgtt cttgacgttt ctgtagtcgt
     1321 tcatcagctg gcaaagcctc ccagtctctt tccaaggaaa ataactgatc acaataagct
     1381 aaacctttag ctcctaagga tgatttatcc gcttgcttgg gggggcgctt caaaaaactt
     1441 ccttctcaca tgcgcccaac atccaacaag ttcagcttct tccagttgac gataagcaga
     1501 cgagcggttc gaagtttacc aagcttagcg tcgccttgct cctaaacctt ggactgctat
     1561 cgcataggca gaactagagg actaaagtcc taagttactg ccgcaaaata tcacaatgca
     1621 catagccaga ataatctcct aggaattctt gtactactga accacttcga cactgatcat
     1681 ggtggtaaag cgtaatccct tgtttctctg ctttacctga caaaaaagtc caatagtaag
     1741 tcagctgact atcactctct agcaccctat aagaagtttc atccgcatga agtaagggct
     1801 gagtcaatag tctctctcgc aagaggttat aaaggggctc caaatagtat tgactcgcct
     1861 tgatatgcca attagagatt tccttacgtg tgattggtaa acccatccta gcccaatctt
     1921 cttcttggcg ataattgggt accttcagat taaacttctg atggatggtg tgagcgataa
     1981 tagaagctga gccaaagtta tgcgctaaag gggctttagg aataggagat ttcacaagct
     2041 tatccagatg attatctttt actcgttatg gacaatgcta tatggcataa atcaagtacc
     2101 ttaaagattc cgactaatat tggctttgca tttattcctc catacacacc agagatgaac
     2161 cccattgaac aagtgtggaa agagattcgt aaacgtggat ttaagaataa agccttttaa
     2221 actttggaag atgtcatgaa tcaactccaa gatgttatac aaggactgga gaaggaggtg
     2281 ataaagtcca tcgttaatcg gagatggact agaatgcttt ttgaaagcag atgagtataa
     2341 aaagaaagtc ctcatttcaa tagaaatcac gactttctga tggatttata gtaaaatgaa
     2401 ataagaacag gacaaatcga tcaggacagt aaaatcgatt tctaacaatg ttttagaagc
     2461 agaggtgtac tattctagtt tcaatctact atatttttgg agtgatagaa aagcccttca
     2521 taagccagtc tacttgttct ggtgtgagag ctttgacatc cttttctgta cttagccaaa
     2581 tcaatctgcc gttctcaaag cgtttatata gtagccaaaa tccttgacca tcccagtaaa
     2641 ggactttaaa gcggtcttta cgtccaccac aaaagagaaa gacttgaccg gagaaaggat
     2701 ccaattcaaa gtgggtttta accagataag ccagtgaatc gattccttgt ctcatatcag
     2761 ttttcccaca cacgagatag acctccccta ggctagatag atgaattgtc atagagcaac
     2821 accttatcca aaagctgttc taccatttcg agattgagag attgaaaaaa acttacttca
     2881 agcttgccaa tacgaatttt aagcagaata tcatttctct ttttagaatc aaaacgacga
     2941 gattgtggaa tctctacagg aacaataggt tgtggcatta aaatatcctc caatagtttt
     3001 actttactaa tagtatacag gaggagctcc atgaatgata gataccttgt tatgacgcgc
     3061 ttactttcta tataattaca tttacgattt actaatccta aatctagatt agtagaaaca
     3121 ttttcattat ctaacaaacc aaaattttga aaaagatatc ctgatactgt caataaaaaa
     3181 agcttagaaa ggcttaaagc cttatccaag ctgatatttg ttcatctaat taataatcta
     3241 aataaaggat ctacttcact ttcataatac gaactaaatt ggctctttct gcctcctcta
     3301 gtttcaattc tatataatga atagtttccg acaagtttgg aataatcgag tattctaaac
     3361 catttacacg tctacgtgtt ttttctattt catcagccat taactgacac gttttttcaa
     3421 cttctgccag tcttagtaat ttataaatta aactattcat tgtagcaaat acatcatcca
     3481 tttcactatt agaagataaa tagctgtatt cactgttctc attttgagaa gtaatattca
     3541 tatgcattct aggaactgtt acactcatga tattttcttt ctcaacaaat aattcaattt
     3601 ctttcgatgg aattgaaaat aattcctcca ccatttgaga attctttaat gatttagcaa
     3661 ctgcaaagga ttttagatta tcaattagat aactttccac ttctttccga agttgattat
     3721 tctcacgaat caaagaaata aatcgcctca tcaattcatc tcttttatcc tttaataact
     3781 tatgtccacg ttcagctgtt gtcaaacgtt cctttaagtt attcaattcc atacgagttg
     3841 gttttacatt caaacgtacc atagataatc actccatttc cggattaaac ttctaccaaa
     3901 ggtaagtatt tatcaagcaa atcatctttg atacgtttta actctgttct aggaagaatt
     3961 gatagtaatt cccacccaag attcaacgta tcttctatat ttcgattttt ataaaatcct
     4021 tggtttatgt actcttcttc aaaacgcttt gtaaacctca catacaattt atctacatca
     4081 gataaagccg attctcctaa tactactgct aactcttcaa cctttttccc ttgggcatag
     4141 gctgcaaaca gttgattcat agttggagca tgatctccac gagttttacc ttctccagat
     4201 cccttatctt ttaatcgaga gagagaaggt aaaacattga ttggtggacg ataaccttga
     4261 ttatacaact catgcgacaa aataatttgc ccttcagtaa tgtatccagt taaatcagga
     4321 attggatgtg ttatgtcatc ttctggcatt gttaaaatag gaatctgtgt caccgaacct
     4381 tttttaccaa ctaagcgacc agccctttcg tatagagttg ataaatttgt atataaatat
     4441 cccggatagc ctcgtctccc tggaacttca cggcgagctg ccgagacttc acgtaacgct
     4501 tcacaatagt tagtcatatc cgtcatgata actagaacgt gcatatcttt ttcaaaagct
     4561 agatactctg ccgcagttaa agcaatgcgg ggagttgcaa tacgctcaat tgcaggatca
     4621 tttgccaagt tcataaataa aaccgaacga tcgatcgctc ctgtttttct gagttcttcc
     4681 ataaaaaact cagcttcttc aaaagtaata cccattgctg caaatacaac cgcaaaattt
     4741 tcatcagaat ttaaaacagt cgcttgtctt gctatctgag cagctaattc attatgaggt
     4801 aagcccgaac ctgaaaatac tggtaatttt tgaccacgta caagagtatt caaatgatca
     4861 atagaggaga tccctgtctg aataaattca tctggataat ctctagatac aggattaata
     4921 gcttgaccat caatatctaa atatttctct ggaattaaat ctggtccacc atcaattggt
     4981 tttcccatcc cattaaaaat acgaccaacc atatcctcag atacagccaa ttctaatgca
     5041 tgaccagcaa aacgaatttt agacttttct aaatttattc cactagatcc ttcaaaaagc
     5101 tgaaccattg ctttatcttc gtggatctct aaaacttgtc cacgacgaat ttctccatta
     5161 tgaagttgaa tttcaactaa ctcattgtaa gacacattat ttacttgttc aacaatcata
     5221 agaggcccaa caacttcact agcagttctg tattctttta taacactcat ttatagacct
     5281 cctgtttcta atatcaaatg aatttgatgt gtaatctcat ttgatataat tttgatttca
     5341 tctaatctat cttctgaaac atatttactt ctcgccatac ggtctcgaac tgccacggta
     5401 ccttccataa tctctgtaaa gtaagaaccc aactctaaag catgatttgc ctgatcagca
     5461 aaagtgagaa tattacttag cattgcttct tgttttgcaa acgaagtgaa tgtatctacc
     5521 gaatcaaaag cgttctgttg caaataatct tctcgaattt gtttagcaat ttccatcgtt
     5581 agtcgttcat tatcagacag agaatcaatt ccaacaagac gaacaatttc ctctaaacta
     5641 gattcccgtt gtaagtagtt catcgcacga gttattttac tattccaatc tgtcttctct
     5701 ttaccatcta tataagtgcc cacactgtct ttatatagtg aataagatgt aagccagtta
     5761 attgcaggaa aatgacgtcg ctgtgccaac ggagcatcaa gcccccaaaa aactttcaca
     5821 atccgtaaag tgttttgagt aactggttct gaaatatctc caccaggtgg cgatacagct
     5881 ccaatagcag taatcgttcc ttcacgttct ggaagcccta gaacctgaga acgtcctgct
     5941 ctttcataat attcagcgat acgacttccc agataagcag gataaccctc atcaccaggc
     6001 atttcttcta gacgtcctga catttcacgt agcgcttctg cccaacgtga agttgaatca
     6061 gccataatgg cgacagagta gcccatatca cgaaaatact cagccatggt aattcctgta
     6121 taaattgaag cctcacgagc agcaacaggc atatttgaag tattagcaat cagaactgtc
     6181 cgttgcataa ttgattgtcc ggtattaggg tcaatcaact caggaaactc attcagtaca
     6241 tccgtcattt catttccacg ttctccacaa ccgacataaa taacaatatc aacattggca
     6301 aatttagcta cttggtgttg tacaactgtc tttcctgctc caaacggtcc aggaactgct
     6361 gcagctcccc ctttggttac tggaaagaat gcatcaataa ctcgttgacc tgtgattaat
     6421 ggttcttctg gaattaaacg tttagaaaca ggacgcgcct tgcggacagg ccatttttgc
     6481 ataagcgttc ctttatagaa actaccgtcc aattttttta tttcatatac aacttcatca
     6541 attgtaaaat cgccagatgc aatagaaacg acttctccag atactccata aggaaccata
     6601 attttatgat taactacctc ggtttccttg acagttccaa gaatatcacc cgtactcact
     6661 ttttgaccaa ttgctatagt ggaatcaaaa tgccacttaa tatctctatc caaacttgga
     6721 acttctaccc cacgaactag aaaatcatta tgagtagcca atttaaatcg atctaatggg
     6781 cgttgtatgc catcaaacat ttgagaaatc aatcctggcc ctaattcaac cgagagaggt
     6841 tctccagttg taacaacagg ttctcccgga ccaagaccag atgtttcttc atagacttgg
     6901 atagatgcct gatctcttct catttcaata atttcaccga ttaaccctag cttacctaca
     6961 cggcaaatat cttgaatatt agcctcctgc atacctgatg caataactag aggtcccgat
     7021 acttttataa tcttcccttg agtcaaagtt attctcctta ctaagtccaa aaattataga
     7081 ataatattac agacaatttt gtacattatt ataaaatatt gtgtcctact gctttctcta
     7141 cattatcctc tatacgtttt aatcctaaat ttaaaccttg tttatgagtc ggtaataaaa
     7201 taatagcagg cacaacttgg gaatcataat ggcgaattgt atctaatatc attgaagcaa
     7261 tgtcttcagt gatataaatg acaccataat cagattgagc taattttctt agtgtattta
     7321 tagcttcttg ttcttggtag gcaggaaata tatcaaaccc aatcatgcta aatggtaaaa
     7381 taatatcacg gctaccaatt atgccaattt tatacttatt agcttccata atgtgggcgt
     7441 atcctttctt ttattgattc aaagggaatt gtattttgaa gagctgatat gatcattctg
     7501 agattcttta cttcaaactc acatcccaat aaatatctag caagaactaa cggcccctct
     7561 acattgtacc ttccttgatc taaagtttta tacaatagta aatcacataa aaattctaac
     7621 tcagaagatg aaattgttgc gtcctgcatc ttcaattcat aagttgaaaa gattgaatct
     7681 aagcttggat ttattttatt gaaccacaca aatatttctt gattttctac aatgtatata
     7741 aattctttag cagaaatact tccttcatct gaaagtaatt gtaaaatatc cccatgactc
     7801 ttattttgag ataaaccacg ttttacagta ataatattat aaaagtcaat catttcgaca
     7861 ataacctgag acagtacctc atctaactca ttagataaaa gtttcagatg tttaaaatat
     7921 gctagatcag ctccgacatc aagtacacga atattattaa aagtttcata ctcattccaa
     7981 attgattcta cttcacgaac cataaaatca ggaagtgtat ctgaatgtaa ggaagaaact
     8041 aaatgtttta aactttctat atcaaaaatc cctattggaa ttaataattt agaaaaatct
     8101 ttcttaattg ccgccttaga ttttaataaa actttgatat tatgataaac atatcgtaaa
     8161 gcaaataaag tcacaattat atcagacgga ctttcagcat aggcccatct ataatcattg
     8221 actaattttg tcattagcga aatctctgtc tgactaggat cttctaagat gtcaatcgat
     8281 aaatgatagg gagttgattc taagataaat gccaatgtct ccgtatcttt ggattgtata
     8341 attttttgaa atttttcttc tgtaataaaa tcgttttctt ttaccgaaat cgtcgtattt
     8401 at
//
LOCUS       DAVHSH010000072         8341 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000072 DAVHSH010000000
VERSION     DAVHSH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.073"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            99..2321
                     /gene="recJ"
                     /locus_tag="VVR08_001886"
     CDS             99..2321
                     /gene="recJ"
                     /locus_tag="VVR08_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU6075734.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            2496..4157
                     /locus_tag="VVR08_001887"
     CDS             2496..4157
                     /locus_tag="VVR08_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6075735.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            4226..5005
                     /locus_tag="VVR08_001888"
     CDS             4226..5005
                     /locus_tag="VVR08_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6075736.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            5117..6337
                     /gene="murM"
                     /locus_tag="VVR08_001889"
     CDS             5117..6337
                     /gene="murM"
                     /locus_tag="VVR08_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU6075737.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            6342..7574
                     /gene="murN"
                     /locus_tag="VVR08_001890"
     CDS             6342..7574
                     /gene="murN"
                     /locus_tag="VVR08_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU6075738.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNSIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            7653..>8341
                     /locus_tag="VVR08_001891"
     CDS             7653..>8341
                     /locus_tag="VVR08_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU6075739.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIY"
BASE COUNT         2527 a         1386 c         1996 g         2432 t
ORIGIN      
        1 atactataaa atgttataaa aaagcaatct ggatagagaa aacgtctaaa tcatgttata
       61 atgaagcaat agaattctta gaaagagtgg atgtcttttt gataacacct acttatgaat
      121 ggcagtttgc cctgcaggta gaagatgcgg attttacaaa gatagccaag aaggctggac
      181 tgggtcctga ggtggctcgg ttattgtttg agagagggat tcagaaccaa gaaagtctga
      241 agaagttttt agaaccttcc ttggaggact tacatgatgc ttatctgctc catgatatgg
      301 acaaggcagt ggagcggatt cgtcaggcta ttgaagaagg ggaaaatatt ctcgtttatg
      361 gagactatga tgcggatggc atgacttcgg cttctattgt gaaggaaagt ttggaacaac
      421 ttggtgctga gtgccgagtt tacctgccaa atcgttttac cgatggctat ggccctaatg
      481 ctagtgttta taaatacttt atcgagcaag aagggatttc cttgattgtg acggtggaca
      541 atggggttgc tggtcatgag gctattgcat tggctcagtc tatgggagta gatgtcattg
      601 tgacagacca tcattccatg cctgaaaccc tgccagatgc ttatgctatt gtccatcctg
      661 aacatccaga tgcggattat ccttttaaat atttggctgg ttgtggagtt gctttcaagt
      721 tggcttgtgc cctgttagaa gaagtgcaag tggaattgct tgatttggtc gctattggaa
      781 ctattgcaga tatggtgagt ctgacggatg aaaatcgtat cttagttcaa tatggtctgg
      841 aaatgttggg tcatacccag cgcattggtc tgcaagaaat gctggacatg gctgggattg
      901 ctgccaacga agtaacagaa gaaacggttg gtttccagat tgctcctcgt ttgaatgcct
      961 tgggccgctt ggatgatccc aatcctgcca ttgatttgtt gactggattt gatgatgagg
     1021 aagcgcatga gattgccctt atgattcacc agaaaaacga agagcgcaag gaaatcgttc
     1081 agtctatcta tgaagaagcc aagaccatgg tggatcctga gaagaaggtt caggtcttgg
     1141 ccaaggaagg ctggaatcct ggggttctag gaatcgtggc tggtcgttta ttggaagaat
     1201 tgggacagac agtcattgtt cttaatatag aagacggtcg tgccaagggc agtgctcgta
     1261 gtgtggaagc ggtcgatatt tttgaagctc tggatcccca tcgagacctc ttcatcgcct
     1321 ttggaggtca tgcaggtgca gcgggtatga cgctggaagt tgagcaactc tcagatttat
     1381 ctcaggtttt ggaagattat gttcgtgaaa aaggtgcaga tgctggtggc aagaataagt
     1441 taaacctaga tgaagagttg gatttggagg cacttagctt ggaaacggtc aaaagttttg
     1501 aacgtttagc tccttttgga atggataatc agaaacctat tttttatatc aagaattttc
     1561 aggtcgaaag tgctcgtact atgggggcag gtaatgccca tctaaagctg aaaatttcca
     1621 agggtgaggc gagttttgaa gtggtagcct ttggtcaagg cagatgggcg acagagtttt
     1681 ctcaaaccaa gaatctagag ttagcggtta aattgtctgt caaccaatgg aatggccaaa
     1741 ctgccctcca gttgatgatg gtggatgcgc gagtggaagg tgttcaactt tttaacattc
     1801 gtggaaaaaa tgcagtcttg ccagaaggtg ttccagtctt ggattttcct ggagaactgc
     1861 caaatcttgc agctagtgaa gctgttgtcg taaaaaacat tccagaggat attactcagc
     1921 tgaagaccat ttttcaggaa cagcatttct ctgctgtcta tttcaaaaat gatattgaca
     1981 aggcctatta tctgacaggt tatgggacta gagatcagtt tgccaaattg tacaagacta
     2041 tttaccagtt cccagagttt gatattcgct acaagctgaa agatttggct gcatatctta
     2101 atattcaaca aatcttgctg gtcaagatga ttcaagtatt tgaagaacta ggctttgtga
     2161 cgataaaaga tggtgtgatg acagtcaata aagaggcgcc aaagcgggag ataggagaaa
     2221 gtcaaattta ccaaaatctc aaacaaaccg ttaaagacca agaaatgatg gcgctgggta
     2281 cggtgcaaga aatttatgat tttttgatgg aaaaagagta gaagttagga aagagttggg
     2341 aaatcaactc ttttttgaaa acagaccttc attttgaaaa tcatcaaaaa aatggtataa
     2401 tggtaggaaa agattcggct gaaagtatca gaacttttag aataagaggg tagagttgcc
     2461 ctataatcaa gataaactaa gattttggag gaaaaatgag taatatcagt ttaacaacac
     2521 ttggtggtgt gcgtgagaat ggaaaaaata tgtacattgc tgaaattgga gagtccattt
     2581 ttgttttgaa tgtagggtta aaatatcctg aaaatgaaca attaggggtc gatgtggtga
     2641 ttccaaacat ggattacctt tttgaaaata gcgaccgtat tgctggggtt ttcttgaccc
     2701 acgggcatgc ggatgctatt ggtgctctac cttatctctt ggcagaggct aaagttcctg
     2761 tatttgggtc tgagttgacc attgagttgg caaagctctt tgtcaaagga aatgatgccg
     2821 ttaagaaatt taatgatttc catgtcattg atgagaatac ggagattgat tttggtggga
     2881 cagtggtttc cttcttccct acgacttact ccgttccaga gagtctggga attgtcttga
     2941 agacatcgga aggaagcatc gtttatacag gtgacttcaa atttgaccaa acggctagtg
     3001 aatcttatgc aactgatttt gctcgtttgg cagagattgg tcgtgacggc gtcctggctc
     3061 tcctcagtga ttcggccaat gcagacagca atattcaggt ggctagtgaa agtgaagtta
     3121 gggatgaaat tacccaaact attgctgact gggaaggtcg tatcatcgtt gcagctgttt
     3181 ccagtaatct ttctcgtatt cagcagattt ttgacgctgc ggataaaaca ggtcgacgta
     3241 tcgtcttgac aggatttgat attgaaaata tcgtccgcac agcgattcgt cttaagaagt
     3301 tgtctttagc caacgaaatt ctcttgatta agcctaaaga tatgtctcgc tttgaagacc
     3361 atgagttgat tattcttgag acaggtcgta tgggtgaacc tatcaatgga cttcgtaaga
     3421 tgtcgattgg tcgccatcgt tatgtagaaa tcaaggatgg ggacctggtc tatattgcta
     3481 cggctccgtc tattgctaaa gaagcctttg ttgcgcgtgt ggaaaatatg atttatcagg
     3541 caggtggggt tgtcaaattg attacccaaa gtttacatgt atcagggcac ggaaatgtgc
     3601 gtgatttgca gctgatgatc aatcttttgc aacctaagta cctcttccct gtccaagggg
     3661 agtatcgtga gttggatgct cacgctaagg ctgccatggc agttgggatg ttgccagaac
     3721 gcatcttcat tcctaaaaag gggacgacca tggcttacga gaatggagac tttgttccag
     3781 ctggatcggt ttcagcagga gatatcttga ttgatgggaa tgccattggt gatgttggaa
     3841 atgttgttct tcgtgaccgt aaggtcttgt cagaggatgg aatttttatc gtggctatta
     3901 cagtcaaccg tcgtgagaag aaaattgtgg ctagggctcg tgttcacacg cgtggatttg
     3961 tttatctcaa gaagagtcgc gatattctcc gtgaaagttc agaattgatt aaccaaacgg
     4021 tagaagagta tcttcaagga gatgactttg actgggcaga tcttaaaggg aaggttcgag
     4081 ataatttgac caagtatctc tttgaccaaa ccaagcgtcg tccagctatt ttaccagtag
     4141 tcatggaagc aaaataatcg ttgaaataaa cagagagaaa gtcgagtttc ggctttttct
     4201 tatagaaaaa tagaaggaga aaatcatggc agtaatgaaa atcgagtatt actcacaagt
     4261 attggatatg gagtgggggg tgaatgtcct ctaccctgat gccaatcgag tggaagaacc
     4321 agagtgtgaa gatattcccg tcttgtacct tttgcacggg atgtctggaa atcataatag
     4381 ttggcttaag cggaccaatg tagaacgctt gcttcgagga actaatctca tcgttgttat
     4441 gcccaatacc agcaatggtt ggtacaccga tacccagtat ggttttgact actacacggc
     4501 tctagcagag gaattgccac aggttctgaa acgcttcttc cctaatatga ctagcaagcg
     4561 tgaaaagacc tttatcgctg gtctttctat gggaggctac ggctgcttca aactggctct
     4621 tacgacaaat cgtttttctc atgcagctag tttttcaggt gccctcagct ttcaaaactt
     4681 ttctcctgaa agtcaaaatc tgggaagtcc agcctactgg agaggtgttt ttggagagat
     4741 tagagactgg acaactagtc cctattctct tgaaagtctg gctaaaaaat cggataaaaa
     4801 gaccaaactt tgggcgtggt gtggcgaaca ggatttcttg tacgaagcca ataatctcgc
     4861 agtgaaaaat ctcaaaaaac taggttttga tgtgacctat agccatagtg ctggaactca
     4921 cgagtggtac tactgggaaa aacaattgga agttttttta acaaccctac caattgattt
     4981 caaattagaa gagagactga cttagtttga acttcagcat agggggagta gaactaaaat
     5041 aaaatatgtt ttcactagac ttttcaaacg aaagtagtag aatagtaata aaatactgga
     5101 ggaaagagat taggaaatgt accgttatca aattggcatt cccacattag aatatgatca
     5161 gtttgtcaaa gaacatgaat tagccaatgt attacaaagt agtgcttggg aggaagttaa
     5221 gtctaattgg caacatgaga agtttggtgt ttacagggaa gaaaaattac tggcgacagc
     5281 tagtattttg attagaactc ttccgctagg ctataaaatg ttttacatcc caagaggacc
     5341 tatattggat tatggggata aagaactctt gaattttgtc attcagtcta ttaagtccta
     5401 tgctcgcagt aagagagcgg tttttgtgac ttttgaccca agtatttgcc tatctcaaag
     5461 tttaatcaat caggaaaaga cagaatttcc tgaaaatctg gctattattg atagtttgca
     5521 acaaatggga gtaaggtggt caggaaaaac ggaggaaatg ggagacacca ttcaacctcg
     5581 tattcaggcg aaaatataca aggaaaattt tgaagaagat aaactttcca agtcaacaaa
     5641 acaggctatt cgaacagcac gaaacaaagg gcttgagatt caatatggtg gactggaact
     5701 attagattca ttttcggagt tgatgaaaaa aactgagaag cgaaaagaga ttcatttgag
     5761 gaatgaagcc tattataaaa aattgttaga taattttaag gacaaggcct atatcacctt
     5821 ggccaccttg gatgtttcta aacgttcgca agaattagaa gaacagttag cgaaaaatag
     5881 agccttggaa gagacgttta ctgagtcgac tcgaatttca aaagtagaag cgcagaagaa
     5941 ggaaaaagaa cgtttgttag aggaattgac cttcttgcag gaatatatag atgtaggtca
     6001 agcgagagtt cctttagcgg ctactttgag tttggaattt ggtactacct ctgtcaatat
     6061 atatgctggt atggatgatg attttaaacg ttacaatgca ccaattttaa catggtatga
     6121 aacggctcgc tatgcctttg agcgaggtat ggtctggcaa aatttaggtg gtgttgaaaa
     6181 ctctctcaat ggtggacttt atcattttaa ggaaaaattt aatccaacga ttgaagaata
     6241 cttgggtgaa tttacaatgc ccactcatcc tctctatcct ctgttaagac ttgctcttga
     6301 tttccgtaaa acattaagaa aaaaacatag aaagtaagta tatggcacta acaacactca
     6361 cgaaagaaga gtttcagact tattctgatc aggtttcttc tcgttccttt atgcaatctg
     6421 tccagatggg ggatttgcta gaaaaaagag gggctcgaat tgtttatctt gctttgaaac
     6481 aagaaggaga aattcaagtt gcagctctgg tttatagctt gcccatgctg ggtggtctgc
     6541 atatggaact caattcgggg ccgatttata cccaacaaga tgctcttcca gttttttatg
     6601 cagagttaaa agaatatgcc aagcaaaatg gtgtattaga gttgcttgta aaaccttatg
     6661 aaacttatca aacttttgat agccaaggta attcaataga tgctgagaaa aaaagtatta
     6721 ttcaaggttt gactgattta ggttatcaat ttgatggctt aacaacaggt tacccaggtg
     6781 gagaaccaga ttggttatac tataaagatt taactgaatt aactgaaaag agtttgctta
     6841 aaagttttag caaaaagggt aaacccttgg tgaaaaaggc tgaaaccttt ggcattcggt
     6901 tgaaaaagtt aaaacgtgaa gaactatcga tttttaagaa tataacaaaa gaaacctctg
     6961 aacgtagaga atatagtgat aaaagtttag aatattatga gcatttttat gatacttttg
     7021 gagaacaagc ggagtttctc atagcaagct taaatttttc ggactatatg agcaaattgc
     7081 aaggtgaaca aagtaaacta gaagaaaact tggacaagtt gcgacttgat ttgagtaaaa
     7141 atcctcattc tgagaaaaaa caaaatcaac tgagagaata ttctagtcaa tttgaaacgt
     7201 ttgaagttcg aaaagcagaa gcgcgagact tgattgaaaa atatggagaa gaagatattg
     7261 ttttagctgg gagtttattt gtttatatgc ctcaggaaac gacttatctc tttagtggtt
     7321 cctacactga gtttaataag ttctatgccc ctgccctgct tcaaaaatat gttatgttgg
     7381 aaagcataaa acgtggaata cctaaataca acttcctagg cattcaaggg atttttgatg
     7441 gaagtgatgg tgttttgcgt tttaaacaga attttaatgg ctatattgta cgcaaagcag
     7501 gtactttccg ttaccatcca tcgcctttaa aatacaaagc tatccagtta ctcaaaaaaa
     7561 tagtaggacg ttaagatgaa aaagtcagta tttagatttc ttttagcttc ttttagtaaa
     7621 ataattctta tttgctagaa aggtggagag acatgcgctg gctttttcgt ttgatagggg
     7681 ctttcttttc ttttgtgtgg cgtttgtttt ggcgtctggt ttggatagtt gtgctcttat
     7741 gtgtgcttgc tttcggactt ctctggtatc tgaacgggga ttttcaagga gcgctaaagc
     7801 aagcagaacg gtcagtaaaa attggtcaac aaagtattga ccaatgggag aaaacagggc
     7861 aactgcctaa gttaagccag acagatagtc accagcattc tgaaggaagg tgggcacagg
     7921 cctctgctcg tatttacctg gatccgcaga tggattcacg ctttcaagag gcttatttag
     7981 aagcaatcca gaactggaat caaactggtg cttttaactt tgaactcgtg actgagtcta
     8041 gtaaggcgga tattacggct acggagatga acgacggagg cactcctgtg gcaggagagg
     8101 cggaaagtca aactaatctc ttaacagggc aattcttgtc cgtaacggtg cggttgaatc
     8161 attattattt gtccaatcca tactatggct actcctatga acgccttgtc catacggcag
     8221 aacatgagtt aggtcatgcg attggcttgg accatacaga tgagaagtct gtcatgcaac
     8281 cagcaggttc cttttatggt atccaggaag aggatgttgc aaacctccga aaaatatatg
     8341 a
//
LOCUS       DAVHSH010000073         8099 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000073 DAVHSH010000000
VERSION     DAVHSH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.074"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(209..1177)
                     /locus_tag="VVR08_001892"
     CDS             complement(209..1177)
                     /locus_tag="VVR08_001892"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6075740.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1322..1976)
                     /locus_tag="VVR08_001893"
                     /pseudo
     CDS             complement(1322..1976)
                     /locus_tag="VVR08_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2001..2498)
                     /locus_tag="VVR08_001894"
     CDS             complement(2001..2498)
                     /locus_tag="VVR08_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU6075741.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2571..3932)
                     /gene="radA"
                     /locus_tag="VVR08_001895"
     CDS             complement(2571..3932)
                     /gene="radA"
                     /locus_tag="VVR08_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU6075742.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(3946..4461)
                     /locus_tag="VVR08_001896"
     CDS             complement(3946..4461)
                     /locus_tag="VVR08_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6075743.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4463..4906)
                     /locus_tag="VVR08_001897"
     CDS             complement(4463..4906)
                     /locus_tag="VVR08_001897"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU6075744.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFVQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(4966..5059)
                     /gene="ffs"
                     /locus_tag="VVR08_001898"
     ncRNA           complement(4966..5059)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVR08_001898"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5092..5559)
                     /locus_tag="VVR08_001899"
     CDS             complement(5092..5559)
                     /locus_tag="VVR08_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU6075745.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5760..7046)
                     /locus_tag="VVR08_001900"
     CDS             complement(5760..7046)
                     /locus_tag="VVR08_001900"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU6075746.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7277..7513)
                     /locus_tag="VVR08_001901"
     CDS             complement(7277..7513)
                     /locus_tag="VVR08_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU6075747.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7778..8032
                     /locus_tag="VVR08_001902"
                     /pseudo
     CDS             7778..8032
                     /locus_tag="VVR08_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2564 a         1953 c         1303 g         2279 t
ORIGIN      
        1 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
       61 gtcgctgaaa cttctgatga cgtacagtca tatttcttct ctttttatta tatcacagtt
      121 ttaaatctag ctttactaga ttcaccgcta ctatctattt attcggaaaa aagacgaaaa
      181 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
      241 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
      301 tctgctcaat cttatcaatc aaacgctctt ctggcagata gatggtatcc aaaacaacca
      361 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
      421 tacagcttgc atagacttca acagcaccag cttccgcaag agcatctgcc gcatgacaaa
      481 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
      541 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
      601 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
      661 ccgggctgac aaccacatag tcagaaccaa ccataccacg acgctcaaaa taatctgcaa
      721 tcagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
      781 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
      841 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
      901 aaggcatgac aacattgaca gattctgcac tcgcacgctt caaagcatct accataatca
      961 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaggata aagacgtgtt
     1021 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
     1081 ttgatttccc caactctatc ccaatctcct gcgccacacg ttctgccaat tctttattag
     1141 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
     1201 cgcttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
     1261 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
     1321 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa taaccataga
     1381 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
     1441 gagagttaaa caataagacc ctgtttcttg ccaaccttct gtcctttata ggctctgtaa
     1501 agcaagtaaa cacctactac agctagacct gaaaaagtcc agtgagaggc aattccaagt
     1561 aaaaacaaaa attttaattt tcgcacagga atcaaagcca aaacaaaaac aagtggcaat
     1621 aatttcaagg gttcttctac caaaggagcc acaatagcac tttcaaaggc atttaaaaat
     1681 ggactatctg ggaaaagaac ccccagtaaa tcatgtatat aagtattagc aaaactagac
     1741 aaccagcctg aaaggaacat ccctcccaat aaagacagaa tcaaaacctt ctttggcaat
     1801 tcccattttt tcccaatatg gaagagaaaa taaagagccg gaatcatgta aaagagagct
     1861 agaaagatag aaactcccat tagtccatat tccgcacctg acctcgaacc gtccgtatag
     1921 tagatggttt catactgtaa accaatacat agcaataaaa tactgctttt cttcatacac
     1981 tttctttcta aatgaagtat ttataattct acgactgtca tacttcctgt atcaacattg
     2041 taaatagcac cagagataat gacatcgtct ggtattaggg gagactcgat aagcagttgc
     2101 atatcctcgc gtacactctc ttctatatct tggaagggca agaaatcctg gtctgacaca
     2161 tctacaccta attcctcttt taaatactcc tgaaaaggtt cattttcaaa ggtctgagca
     2221 ccacagtctg tatggtgcaa taccacaatc tctcttgtcc ccatttgttg ctgggaaata
     2281 actagcgaac gaatcatgtc ttcagtcact cgaccacctg cattccgcaa gatatgagca
     2341 tccccaagtg ccaagcccag agcttgcgca acgtgcagac gagagtccat acaggtcaca
     2401 atagctactc ttgttttggg tttaagtggc agatttaact gcccatgtag ggcaacataa
     2461 gcctgattag cttgcataaa ctgttcaaaa tacgacacga ttccctcctt gaaaatttga
     2521 tagtcaaata tttctcctat cttatcattt ttaagagaat ttgtcacgga ttatgcaaag
     2581 acctttttca aaacttcctg aatcgttgtc acgccaatga cctgaatttc cttaggcaga
     2641 gtgattcctg tcaaggaatt cttaggtaca taaatcttag taaagcccag tttagcagct
     2701 tcgttgatgc gttgctcaat acgattcacg cgccgaatct ctcctgtcaa gcccagttct
     2761 ccgacaaaac attcctgagg attagttggc ttgtctttgt agctcgaagc aatagcaact
     2821 gcaacagcca agtcaatggc aggttcatcc aatttaacac caccagcaga tttgagatag
     2881 gcatcctgat tttgcaagag aagccctgcc cgtttttcca aaacagccat aatcaagcta
     2941 gcacggttaa aatcaagtcc tgtcgtagta cgcttggcat ttccaaacat ggtcggtgtt
     3001 accaaagcct gaacctccgc caaaatcgga cgcgtccctt ccatggttac aacgatggag
     3061 gaaccagtcg ccccatccaa acgctcttct aggaaaactt gactcggatt gagtacctca
     3121 accaagccgc ccgactgcat ctcaaaaatc ccaatctcat tagtggaacc aaaacgattt
     3181 ttgaccgctc tcaaaatacg aaaggtgtgg tgacgctccc cttcaaagta aagcaccgta
     3241 tccaccatat gctccaacat acgaggccca gccaaggttc cttctttggt cacatgacct
     3301 acgataaaga tggcaatgtt attggtcttg gccaactgca tgagttcagc ggtcacttca
     3361 cgcacctgag aaacagaccc ctgcacccct gaaatctcag gagacatgat ggtctggatg
     3421 gaatcaataa tgagaaagtc tggctgtata cgctccactt ctgcacgaac actctgcata
     3481 ttggtctctg catagagata aaactcacta tcaatatcac ctaagcgctc tgcacgtagt
     3541 ttaatctgct gggcagactc ctccccactg acatagagaa ctgtccccac ttgggacaac
     3601 tgggttgaga cttgtaggag aagagttgat ttcccaatcc caggatcccc accgatgagg
     3661 acgagacttc ctggtaccac tccgcctcca agcacacggt tgaattcctc catctccgtc
     3721 ttggttcgat tgacattgat ggaagtcacc tcagctagtt tcatgggctt ggttttctca
     3781 cctgtcaagg acacacgcgc attcttaact tcggcaacct caacctcttc cacaaaagaa
     3841 gaccaagacc cacagttggg gcaacgtccc agatatttag gggaattata cccacaattt
     3901 tgacatacaa atgtcgcttt tttctttgcg atgacaaacc tctttctata tctctaactc
     3961 acactcaatc acttggcaaa aatcaatctt ctcatttggc acaaactggc gcatgagcat
     4021 tcgatgagca acaactacca cagtctgatg ttctcgatac ttagacatac attctagaaa
     4081 ccgagacttc atttccgtag ctgtctcata ttgaatagga ctattaggaa gcaactcccc
     4141 cttgttttct aaaaacagtc ttctagctgt ttcaaagttt tctattcctg ttttatagac
     4201 ctgccattca tgtaataaag gctctactct taaaggaaga cccgtagcac agaccacata
     4261 cgaagccgtt tctaaagctc ttgtgactgc agaagatacg attatttcag ctgacgagag
     4321 taaaggattt ttgctcaatt tctggacttg ctgccgtccc atctcagaca agggtgccaa
     4381 atctatccca aatcctatat aagaacgctc ctctaactca cggtaatctg gctccccatg
     4441 acgtacaaag ataatcttca ttctagtgcc ctgtcgatcc aaatccacca gttcgaacgc
     4501 catcagctgc atctccatct gcaattaaga aagtagcaaa aacagcctgg acaatacgtt
     4561 ccccaacttc aagaacaacc tcttggtctg tgatattctt catctgcaca aaaatatgcc
     4621 cttcatttcc aggatttcca taataatccc catcaatgac cccaactgag ttaattaaaa
     4681 ccaagccctt cttacgagga tttgaagaac gatcatagag gtagagaacc tcagtcggct
     4741 gcatataagc cttaacccct gttggaacca agacaatctc tcctggcgca acaactgtac
     4801 gcacagcaac ctttaagtcg taaccagccg catgcgctgt ctcacgcttg ggcaataaat
     4861 tttcatctgt aaaactcgaa accaattcaa aaccacgaat tttcataatt ttctcttttc
     4921 tattatcatt tattctagat tattctatct tatttattcg gaaaaagcac gaaaaaagag
     4981 cacacaattc aaatcgctta gggctgctgg attcctcccc tgacccgctt cacgcagaac
     5041 tgttgctcca ctatttatta tatcacattc ctattcattt taaaagcaaa attatttttt
     5101 ccgtctattt ctaaaaaaat cctgcatgat agctgcgcat tcatcttcca aaattcctat
     5161 ttcaacctcc acacgatgat tgagacgctc atctgtcaag atattgtaca aactcccagc
     5221 agcgccaaat ttctggtttt tagccccata gaccacattt ggaatgcggg caagcccaat
     5281 cgctccacta cacatgacac aaggttcaat ggtcacaaaa agtgtgcaat ccagcaagcg
     5341 ccagctctcc tcactcaagt tcgcatcctc tatagccata atttccgcat gcataaccgc
     5401 tcgctgtaat tcctcacgcg cattatgccc acgaccaatg atttccccat ctttgacaat
     5461 cacacaacca attggaattt catcgtgttc aagagcaatc tcagcctctc tcaaagcctc
     5521 cctcataaag acttcttttt cttcaagcgt ataatacatc tcttttctct tttcctactt
     5581 atcgatttta ttattatatc atgaatccca acacaaaaga agccaccgaa tgcggtgact
     5641 ctatagggag attattatga aaaagaaaag tttaggatat ttgttacaac aagttaggag
     5701 gtcttcttgt aaccgtctat agtatacccg acctatctta aacaaatctt aaaaatctct
     5761 taggaccaaa cactttctaa aatatttgtt tgttcacgac caggacctac tgagaaagta
     5821 gaaatacgaa cgccaaccaa ttcactcaca cgacgaacat agttacgcgc attctcagga
     5881 agatcttcca aattgcgaac tccggtaata tcttctgacc aacctggcaa ctcttcatag
     5941 ataggcttgc aacgtttcaa ttgctcaaga ctagctggat agtagtcaat acgttgaccg
     6001 tcaagatcat aggccacaca gattttcaca gtatccaaac cgctcaaaac atcaatagag
     6061 ttcaaagaaa ggttagtaat accagaaaca cgacggctat gacgcatcac aactgagtca
     6121 aaccaaccta cacgacgtgg acgaccagtt gttgtaccat attcatgacc cacttcacgg
     6181 atacgttctc ccacttcatc aaacaactca gttgggaaag gaccatctcc tacacgactc
     6241 gtataagctt tacatacacc tacaaccttg tcaatcttgc ttggaccgac accagaacca
     6301 attgtcacac caccagctac agggtttgat gacgtaacaa atggataagt accttggtcg
     6361 atatctagca taacaccttg tgcaccttca aaaagcacac gtttgccatt atcaagcgca
     6421 tcattcaaga taacagatgt atctatcacg tatttcttga tttgttgacc atattcgtaa
     6481 tattcttcaa aaatatcatc gaaaacaatc gctttactgt catacaattt ttcaaaaaga
     6541 cgattctttt cagcaaggtt acgttctaaa cgctcacgga aaatatcttt atctaaaaga
     6601 tctgcaatac gaattccaac acgagcagcc ttgtccatat aagctggacc aattccctta
     6661 attgtcgtac caatcttatt gtcgccctta gcttcttctt gcaagcgatc caactcgata
     6721 tgataaggca aaataacatg cgcacgatca gaaatacgca agttatcagt tgttacacct
     6781 tcctcatgaa gatagctcaa ctcttttaca agagatttag gatttacaac cataccattc
     6841 ccaatgacag atattttttc agggaagaaa atcccagatg gaatcaagtg caacttaaat
     6901 ttcttaccgt caatcacaat cgtgtgacca gcattatcac caccttggta acgtgcaatt
     6961 acttctgcat tcgctgaaag gaagtctgta atcttccctt taccttcatc accccattgg
     7021 gtacctacaa caacaactga agtcataatt ttgtctgagc cctcaggctc ttcctttctc
     7081 acatacatgg caggactctc acctgcaatt atatcttaca atttattata ataaaaaatc
     7141 gcctttttat caagaagaaa caatagaaag atttgctatt tccaactatt aaaaaatgat
     7201 ttagaaaaat tactagctat ttactattat ctttccataa aagagtaaat tagttcggaa
     7261 atttactaaa attacctcaa caagaaataa acccccgatt cattaccaat ttttcaagat
     7321 acaaacgata agcaacacga taatggtaaa cgataaaatc cctacgacaa ccaatgccat
     7381 atctcactaa ataataaatt aaaaatttaa aatgaacatg ttcccagtca aaattatcac
     7441 caaatgtagg accatactct tcttcaatac tatcatagaa attagccatc tgctcataaa
     7501 ttttttgtaa cataatcaaa tactcctttt cttttttata aacttattct aacaaaaaat
     7561 tttacacatt cactatcaat tcctgaattg ttaaaatacc agcctcaaca agataaaaat
     7621 aggaaaagtt gacaaaatag aaacaaattt gctacctaaa tttcaaacga ttaaagttct
     7681 aaaaagaccg ccttaaaact tttgggtaaa tcctattaga actataatat ttttatatag
     7741 gtattatggt tctgattttc tagtataaaa aattcaaact agaattcttc ttagaaaagg
     7801 ccgttttaag tgctatcact gttcaaaaat gagggtcgct gaaacttcta tcgtcaagaa
     7861 gaatcatcaa attccttgta tcatcaacca aaagattgct cagaagctaa ttaaaaagac
     7921 ttctatgacc gacattgatc atcagttgtc tatttcaact tcaactgtca ttcgcaagat
     7981 caatgatttt cactttgagc atgatttttc gcgtcttcct gagattatgt cctaggacgt
     8041 tgaaacagtc cggggagtga ctgtttcaat cgggagatgg agatgagctt tattgctca
//
LOCUS       DAVHSH010000074         7238 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000074 DAVHSH010000000
VERSION     DAVHSH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.075"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(389..2080)
                     /locus_tag="VVR08_001903"
     CDS             complement(389..2080)
                     /locus_tag="VVR08_001903"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU6075748.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2216..2662
                     /gene="argR"
                     /locus_tag="VVR08_001904"
     CDS             2216..2662
                     /gene="argR"
                     /locus_tag="VVR08_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6075749.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2713..5247
                     /gene="mutS"
                     /locus_tag="VVR08_001905"
     CDS             2713..5247
                     /gene="mutS"
                     /locus_tag="VVR08_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU6075750.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5394..7088
                     /gene="patA"
                     /locus_tag="VVR08_001906"
     CDS             5394..7088
                     /gene="patA"
                     /locus_tag="VVR08_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU6075751.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMIQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKNVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1986 a         1402 c         1692 g         2158 t
ORIGIN      
        1 gaaatcatcg taaacgcttc ggattacgaa tgaatttgat tgctggtatt atcaatcatg
       61 aactaggatt ctagttttgc aggaagtcta ttatttggtt aggtgaatta gtgaagcgtt
      121 taggcaagtg tctctggtta cgacgtcatg gcctctaaat cgattatatt taggggtcat
      181 gactagtgaa gcagttagct agttcgcata taagcggcta gcgtctaaca attaggaact
      241 ttagttccaa taactttaag attacgacgt tttaggacat aaatcgatca tatttatgtc
      301 ctaaaactag tgaagcgcct agccaaagtc cgaataggat ttggcgttag ttacttagat
      361 tgctttgcaa tcaagtaact ttggcgattt acatcttctc tggcgcttct actccaagca
      421 agcgaagggc ttctttgaga acgactgcgg ttgcgtagct gagggctaga cggctgtcgc
      481 gttctgggct ttcatccaag atacgtgtat gtgcatagta tttgttaaag gattgagcca
      541 ggctaattgc aaatttagca atgatagaag gttcaaagtt atctgccgca cggttgataa
      601 tacgtgggaa gtcttgaatg agtttaatga tttcccagct ttcagtatca ttcaagctat
      661 agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa gatagattgg atacgagcgt
      721 aggcatattg aacgtaaggt ccagtttcac cctcgaagga taccatagct tctaggtcga
      781 agtcgtatcc atttgtacgg tcagttttga ggtcatagaa tttaatggct ccaaccccaa
      841 cagcatgtgc tacttggtct ttgttttcta gttcaggatt tttagcctcg atttggacct
      901 tggcacggct aacagcctct gcaacagtag gctctagcaa gatgacattc cctttacgag
      961 tagagagctt cttcccttct tttgtaacca gaccaaaagg aacgtgggta atgtcgtcac
     1021 tccaatcgta gcccatctct tgcaagacag ctttgagttg tttaaagtgg gcagattgct
     1081 cttgaccaac gacgtagata gatttagcaa attggtattc atttttacgg tagagggctg
     1141 cagccaagtc acgtgtgata tagagagttg caccatcaga cttcttgatg agggctggat
     1201 gttcaattcc atatttctca agattcacaa cttgggcacc ttctgattca agaagtagtc
     1261 ctttttcaga aagaatgtct acaactgcat ccatcttatc attgtagaag gcttctccgt
     1321 tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg gttaaattcc actaaacttt
     1381 catcgcggaa ccattgccaa agagcgagag cttcctcatc tccattttca agtttacgga
     1441 accattcgcg cgcttcttca tccaagctag ggtcattttc agcttcagcg ttgatgcgga
     1501 catagagttt aaggagttca tcgattggat gagcttttac agcttcttcg tcgccccatt
     1561 ttttgtaggc aacaatcaac atcccaaatt gtttacccca gtctcccaaa tggttgacct
     1621 tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa gctatctccg ataacagttg
     1681 aacgcaggtg gccaatagaa aatggtttag cgatattcgg actagacatg tcgataacaa
     1741 cattttcttg tttgccaata ttttggtcag catagtgttc tttttcagtg gtaacagctt
     1801 gcaatacttg agcagaaatg gcagatttat caaggaaaaa gttaacgtaa ggtcctgttg
     1861 cgacaacttt ttcaaaggct tggctgttca ttttttcagc cagttcagcc gcaatcattt
     1921 gtggtgcttt acgttcgact tttgcaagag aaaaagcagg gaaagcaatg tctcccattt
     1981 ctgagttttt aggggtttcc agtaacttta aaatagcctc ttggtccagg ctatcaatga
     2041 tgctagataa ttcgctagca atcaattctt ttgtattcat taagagctcc tttttggact
     2101 tttctactat tttatcacaa ttttaaagaa agaagaaaaa atttttgaaa tctcctgttt
     2161 ttttggtata atatggttat aaatatagtt ataaatatgc acgcaagagg attttatgag
     2221 aaaaagagat cgtcatcagt taataaaaaa aatgattact gaggagaaat taagtacaca
     2281 aaaagaaatt caagatcggt tggaggcgca caatgtttgt gtgacgcaga caaccttgtc
     2341 tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa aatgatatgg tgtattatgt
     2401 actagtaaat gagacagaaa agattgattt ggtggaattt ttgtctcatc atttagaagg
     2461 tgttgcaaga gcagagttta ccttggtgct tcataccaaa ttgggagaag cctctgtttt
     2521 ggcaaatatt gtagatgtaa acaaggatga atggatttta ggaacagttg ctggtgccaa
     2581 taccttattg gttatttgtc gagatcagca cgttgccaaa ctcatggaag atcgtttgct
     2641 agatttgatg aaagataagt aaggtcttgg gagttgctct caagacttat ttttgaaaag
     2701 gagagacaga aaatggcgat agaaaagcta tcacccggca tgcaacagta tgtggatatt
     2761 aaaaagcaat atccagatgc ttttttgctc tttcggatgg gtgattttta tgaattattt
     2821 tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt ccttaacgag tcgcaacaag
     2881 aatgccgaca atccgatccc tatggcgggt gttccctatc attctgccca acagtatatc
     2941 gatgtcttga ttgagcaggg ttataaggtg gctatcgcag agcagatgga agatcctaaa
     3001 caagcagttg gggttgttaa acgagaggtt gttcaggtca ttacgccagg gacagtggtc
     3061 gatagcagta agccggacag tcagaataat tttttggttt ccatagaccg cgaaggcaat
     3121 caatttggcc tagcttatat ggatttggtg acgggtgact tttatgtgac aggtcttttg
     3181 gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg ctcgagaagt ggtgttgggt
     3241 tatgacttgt ctgaggaaga agaacaaatc ctcagccgcc agatgaatct ggtactctct
     3301 tatgaaaaag aaagctttga agaccttcat ttattggatt tgcgattggc aacggtggag
     3361 caaacggcat ctagtaagct gctccagtat gttcatcgga ctcagatgag ggaattgaac
     3421 cacctcaaac ctgttatccg ctacgaaatt aaggatttct tgcagatgga ttatgcgacc
     3481 aaggctagtc tggatttggt tgagaatgct cgctcaggta agaaacaagg cagtcttttc
     3541 tggcttttgg atgaaaccaa aacggctatg gggatgcgtc tcttgcgttc ttggattcat
     3601 cgccccttga ttgataagga acgaatcgtc caacgtcaag aagtagtgca ggtctttctc
     3661 gaccatttct ttgagcgtag tgacttgaca gacagtctca agggtgttta tgacattgag
     3721 cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa aggatctctt gcagttggcg
     3781 actaccttgt ctagtgtgcc acggattcgt gcgattttag aagggatgga gcaacctact
     3841 ctagcctatc tcatcgcaca actggatgca atccctgagt tggagagttt gattagcgca
     3901 gcgattgctc ctgaagctcc tcatgtgatt acagatgggg gaattatccg aactggattt
     3961 gatgagactt tagacaagta tcgttgcgtt ctcagagaag ggactagctg gattgctgag
     4021 attgaggcta aggagcgaga aaactctggt atcagcacgc tcaagattga ctacaataaa
     4081 aaggatggct actattttca tgtgaccaat tcgcaactag gaaatgtgcc agcccacttt
     4141 ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa ccgaagaatt agcccgtatc
     4201 gagggagata tgcttgaggc gcgtgagaag tcagccaacc tcgaatacga aatatttatg
     4261 cgcattcgtg aagaggtcgg caagtacatc cagcgtttac aagctctagc ccaaggaatt
     4321 gcgacggttg atgtcttaca gagtctggcg gttgtggctg aaacccagca tttgattcga
     4381 cctgagtttg gtgacgattc acaaattgat atccggaaag ggcgccatgc tgtcgttgaa
     4441 aaggttatgg gggctcagac ctatattcca aatacgattc agatggcaga agataccagt
     4501 attcaactgg ttacagggcc aaacatgagt gggaagtcta cctatatgcg tcagttagcc
     4561 atgacggcgg ttatggccca gctgggttcc tatgttcctg ctgaaagcgc ccatttaccg
     4621 atttttgatg cgatttttac ccgtatcgga gcagcagatg acttggtttc gggtcagtca
     4681 acctttatgg tggagatgat ggaggccaat aatgccattt cgcatgcgac caagaactct
     4741 ctcattctct ttgatgaatt gggacgtgga actgcaactt atgacggaat ggctcttgct
     4801 cagtccatca tcgaatatat ccatgagcac atcggagcta agaccctctt tgcgacccac
     4861 taccatgagt tgactagtct ggagtctagt ttacaacact tggtcaatgt ccacgtggca
     4921 actttggagc aggatgggca ggtcaccttc cttcacaaga ttgaaccggg accagctgat
     4981 aaatcctacg gtatccatgt tgccaagatt gctggcttgc cagcagacct tttagcaagg
     5041 gcggataaga ttttgactca gctagagaat caaggaacag agagtcctcc tcccatgaga
     5101 caaactagtg ctgtcactga acagatttca ctctttgata gggcagaaga gcatcctatc
     5161 ctagcagaat tagctaaact ggatgtgtat aatatgacac ctatgcaggt tatgaatgtc
     5221 ttagtagagt taaaacagaa actataaaac caagactcac tagttaatct agctgtatca
     5281 aggagacttc tttgacaatt ctccactttt ttgctagaat aacatcacac aaacagaatg
     5341 aaaaggagct gacgcattgt cgctcccttt tgtctatttt ttaaggagaa agtatgctga
     5401 ttcagaaaat aaaaacctac aagtggcagg ccttggcttc gctcctgatg acaggcttga
     5461 tggttgctag ttcacttctg caaccgcgtt atctgcagga agtattagac gccctcctta
     5521 ctgggaaata tgaagctatt tatagtatcg gggcttggtt gattggtgtg gccgtagtcg
     5581 gtctagttgc tggtggactc aatgttgtcc tcgcagccta tattgcccaa ggagtttcat
     5641 ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt ttcttatgct gatattgaac
     5701 aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga tatcaaccag attcagaacg
     5761 ttgtcatgat gaccttccaa attcttttca gacttcccct cttgttcatc ggttcgttta
     5821 tcctagcggt tcaaacctta ccttctctgt ggtgggtgat tgttctcatg gtagtcttga
     5881 tttttggttt gactgctgtc atgatgggaa tgatggggcc tcgttttgct aaatttcaaa
     5941 cccttcttga gcgcatcaat gccattgcca aggaaaattt acgtggcgtt cgtgtggtca
     6001 agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac agaggtctca aacgagcttc
     6061 ttggtcaaaa cctttacatt ggttatgcct tttcagtagt ggaacccttt atgatgttgg
     6121 ttggttacgg ggcggtcttc ctctctattt ggctggtcgc gggaatgatt cagtcggatc
     6181 cgtctgttgt tggttccatc gcttcttttg ttaattacct aagccagatt atctttacca
     6241 ttgttatggt tggatttttg ggaaattctg tcagccgtgc catgatttcc atgcgtcgta
     6301 ttcgagaaat tcttgacgca gagccagcta tgaccttcaa ggatatccca gatgaagagt
     6361 tggttggaag tcttagcttt gaaaatgtga cctttaccta tccaatggac aaggaaccga
     6421 tgctgaaaaa tgtgagcttt actattgaac ctggtcaaat ggttggtgta gttggagcga
     6481 ctggtgcagg aaagtcaacc ttggctcaat tgattccacg tctctttgat ccacaggacg
     6541 gggccattaa aattggtggc aaggatattc gagaagtgag tgaaggaacc ctgcgtaaaa
     6601 cagtttccat cgttctccaa cgtgccattc tttttagtgg aacgattgca gataacttga
     6661 gacaggggaa gggaaatgct accctatttg aaatggagcg cgcagccaat attgcccagg
     6721 ctagtgaatt cattcatcgt atggagaaaa cctttgaaag tccagttgaa gaacggggaa
     6781 ccaatttctc tggtggacaa aaacaaagga tgtcgattgc gcgtgggatt gtcagcaatc
     6841 cacgtattct gatttttgac gattcgacct cagccttgga tgccaaatca gagcgcttgg
     6901 tgcaagaagc tttgaataag gacttgaagg ggacgacaac cattattatt gctcaaaaaa
     6961 ttagctcggt tgtccatgca gacaagatct tggttctaaa tcaaggacga ttgattggtc
     7021 aaggtacgca tgcagacttg gttgccaaca atgccgttta ccgtgaaatc tatgaaacac
     7081 agaaatgaaa gacaaactat aagaaaagtc aatagtttta tctaaactat ttcttatttc
     7141 aatttgatga tttggcgatg attttagagc acggcaaaaa gcccttgaaa aagtccattt
     7201 tttcaaaggt aatcctgtgt tgatttcaga aattacat
//
LOCUS       DAVHSH010000075         7072 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000075 DAVHSH010000000
VERSION     DAVHSH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7072
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.076"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            1..659
                     /locus_tag="VVR08_001907"
                     /pseudo
     CDS             1..659
                     /locus_tag="VVR08_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            720..1682
                     /locus_tag="VVR08_001908"
     CDS             720..1682
                     /locus_tag="VVR08_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6075752.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1859..2866
                     /gene="gap"
                     /locus_tag="VVR08_001909"
     CDS             1859..2866
                     /gene="gap"
                     /locus_tag="VVR08_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU6075753.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2933..3769)
                     /locus_tag="VVR08_001910"
     CDS             complement(2933..3769)
                     /locus_tag="VVR08_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6075754.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3895..6090
                     /locus_tag="VVR08_001911"
     CDS             3895..6090
                     /locus_tag="VVR08_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6075755.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6143..6295
                     /gene="rpmG"
                     /locus_tag="VVR08_001912"
     CDS             6143..6295
                     /gene="rpmG"
                     /locus_tag="VVR08_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6075756.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6305..6481
                     /gene="secE"
                     /locus_tag="VVR08_001913"
     CDS             6305..6481
                     /gene="secE"
                     /locus_tag="VVR08_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU6075757.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6536..7072
                     /gene="nusG"
                     /locus_tag="VVR08_001914"
     CDS             6536..7072
                     /gene="nusG"
                     /locus_tag="VVR08_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU6075758.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2208 a         1252 c         1515 g         2097 t
ORIGIN      
        1 tagacttaaa aactatctta ctgacaatcc agacgcttat ttgactgaaa tagcttctga
       61 atttggctgt catccaacta ccatccacta tgcgctcaaa gctatgggct acactcgaaa
      121 aaaagaacca cacctactat gaacaagacc cagaaaaagt agccttattt cttaagaatt
      181 ttaatagatt aaagcaccta gcacctgttt agattgacga aacaggattc gatacttatt
      241 tttatcgaga atatggtcgc tcattaaaag gtcagttaag aagaggcaaa gtatctggaa
      301 gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgagtta atcgttccaa
      361 tgacttacga agagacgatg acgagcgact tttttgaagc ttggtttcag aagtttttct
      421 taccaacatt aaccacacca tcggttatta ttatggataa tgcaagattc catagaatgg
      481 ggaagctaga acttttatgc gaagagtttg ggcataaact tttacctctt cctccctact
      541 cacctgagta caatcctatt gagaaaacat gggctcatat caaaaagcac ctcaaaaagg
      601 tattaccaag ttgcaatacc ttttatgagg ctcttttgtc ctactcttgt ttcaattgac
      661 tatagttcac ggatacagtt gggaaagaag ctattaaaca tttggagagt ccttttggga
      721 tgaacatgtc aaatattact atagatgggc aagaaatgga tctgagtcaa acgatgcctt
      781 cttatgctca agtagtgagt ctttatgatg atacaagtat ctctgttagt aataatgaga
      841 cggacaaagt gttggctggc tccctctata ctgatacaaa tgaacaggga ttaacgattc
      901 caagcagttt actaaaaaat tggaatgaac agacaggaaa aaatttgaca gctaatgatc
      961 ttattggcaa atcagtctca gccagcattg tagaaagtgc tgccgaaact agtaagattg
     1021 ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga agatgacatg gaggacagca
     1081 acagtttcat gctgtctcat caaatggaaa cgattttgaa agaggctgga tttacgaaag
     1141 ctgtatctta ttttatcttg gaactcaaag atccatcaca gacaaaagta gtaacagaag
     1201 aattacagaa aaataagaag tatactgtgc tttctcaaca gagagttctt gatattgtga
     1261 ttacctttat tcgtgttatt cagggattat tgattgtgct ttcatcacaa gctattgtgg
     1321 tagcagcggt tatgattggt atcattattt acatcaatat catgcaacgt tccaaggaaa
     1381 taggtgtcat gaaagcagtt ggttatcaga atcgtggtgt caaaggaatt tttatttacg
     1441 aggctatctg gattgtaggc atcgccttgc tgctggcatt tttggttgca caaggggtgg
     1501 gaagtttggc gaatgcgatt gtaagtcact tttacccatc catcactaag gtttttgaat
     1561 taaatctttt atctgtttta ggaactctag ttttcgctct attacttggt tatgtctcag
     1621 cctacttccc ggcgcgtaag attagtaaaa tggatcctgt agaatcgtta cgctatgaat
     1681 aataagggat tccttgattt acagtcttaa aaagaaactc acatagaaaa acaatggcca
     1741 tacttgcaat tcaactcaaa tagttgtata ataggtttgt tgaaaggtga tttgtagtga
     1801 ttcaagttac tcttttcaca ataaaaattt catgattttc ataaggagga aatcactaat
     1861 ggtagttaaa gttggtatta acggtttcgg acgtatcggt cgtcttgctt tccgtcgtat
     1921 ccaaaacgta gaaggtgttg aagttacacg catcaacgac cttacagatc cagttatgct
     1981 tgcacacttg ttgaaatacg acacaactca aggtcgtttc gacggtactg ttgaagttaa
     2041 agaaggtgga ttcgaagtta acggtaaatt cgttaaagtt tctgctgaac gtgatccaga
     2101 gcaaatcgac tgggctactg acggtgtaga aatcgttctt gaagctactg gtttctttgc
     2161 taagaaagaa gcagctgaaa aacaccttaa aggtggagct aaaaaagttg ttatcactgc
     2221 tcctggtgga aacgacgtta aaacagttgt attcaacact aaccacgacg ttcttgacgg
     2281 tactgaaaca gttatctcag gtgcttcatg tactacaaac tgcttggctc caatggctaa
     2341 agctcttcaa gataactttg gtgttgttga aggactgatg actactatcc acgcttacac
     2401 tggtgaccaa atgatccttg acggaccaca ccgtggtggt gaccttcgcc gtgctcgcgc
     2461 tggtgctgca aacatcgttc ctaactcaac tggtgctgct aaagctatcg gtcttgtaat
     2521 cccagaattg aacggtaaac ttgacggatc tgcacaacgc gttccaactc caactggatc
     2581 agttactgaa ttggtagcag ttcttgaaaa gaacgttact gttgatgaag tgaacgcagc
     2641 tatgaaagca gcttcaaacg aatcatacgg ttacacagaa gatccaatcg tatcttcaga
     2701 tatcgtaggt atgtcttacg gttcattgtt tgacgcaact caaactaaag ttcttgacgt
     2761 tgacggtaaa caattggtta aagttgtatc atggtacgac aacgaaatgt catacactgc
     2821 acaacttgtt cgtactcttg aatacttcgc aaaaattgct aaataattct tgagttgata
     2881 gaaagcaagg ctttgtggtc ttgcttttta tatggaaaaa tggatgacac gatcatccat
     2941 tcttttttaa ttctttttca aatgtatttg aaagggtagt gaaagttagc ctctctaaag
     3001 taagtgggtg ggtaaaggaa agtcggaagg catgaagcat aagccggctt gtctttgatt
     3061 tactattata gagagggtct cccaggatag gaagattatg atgcaaaagg tgcacacgaa
     3121 tctgatgggt tcgccctgtc tttagcttgc aatgagccaa ggaagtcttg tttgagaatt
     3181 gctttaatct gcttacatgc gtttcagcat attgcccatt ttttgcatca actattcttt
     3241 ttctacgatc atggcgatca cgtccaattt tgtctctgaa aacaagttct tttctgttga
     3301 tatttccatc aactagagcc caatattctc tagaaatctc ttttttctcc aataagcgat
     3361 tgagaatggg caggataaaa ggatttttgg caaagagaac taagccactg gtttccatgt
     3421 ccagacgatg aacgacatag caggtttggc caacataggt actaacatgg ttaagaaggg
     3481 caatttcgtt tggttgatta ccatgcgttt tcatcccctc tggtttgttt acaataatca
     3541 agtgttgatc ttgataaact tcctgcacta agtctgggtt gccccaaggg atcgtctttt
     3601 ggggataatc ttcctcgtca aaagtcaact ggcaaacatc tccaggattt acgatttcgt
     3661 tccagtggac ttcttcttga tttatcaaaa tatgtttctt gattctcaaa aaatgacgga
     3721 tttttctagg gatgaggagt tgttcctcaa gtaattgctt taccgtcatt tgaggtagag
     3781 aggcgggtaa tgtaaatgtg aattgcatac agatattgta acaaaaaaag ccctatttgg
     3841 ataggaaata gctaaattct tgtcttccta tgatgaagat gataaaataa acgcatgaaa
     3901 ttagataaat tatttgagaa atttctttct ctttttaaaa aagaaacaag tgaactagag
     3961 gactctgatt ctactatctt gcgtcgctct cgtagtgatc gaaaaaaatt agcccaagta
     4021 ggtccgattc gaaaattctg gcgtcgttat catctaacaa agattatcct tatactaggt
     4081 ttgagtgcag gattgctagt tggaatctat ttgtttgctg tagccaagtc gaccaatgtc
     4141 aatgatttgc aaaatgcctt gaaaactcgg actcttattt ttgaccgtga agaaaaagag
     4201 gctggtgcct tgtctggtca aaagggaacc tatgttgagc tgactgacat cagtaaaaac
     4261 ttgcagaatg ctgttattgc gacagaagac cgttctttct ataaaaatga cgggattaac
     4321 tatggccgtt tcttcttggc tattgtcact gctggacgtt caggtggtgg ctctaccatt
     4381 acccaacagc tggctaaaaa cgcctattta tcgcaggatc aaactgttga gagaaaagcg
     4441 aaagaatttt tccttgcctt agaattaagc aaaaaatata gtaaggagca aattctaacc
     4501 atgtacctta acaacgctta ttttggaaat ggtgtgtggg gtgtagaaga tgcgagtaag
     4561 aaatactttg gagtttctgc atcagaagtg agtctggatc aagctgcgac tctggcaggg
     4621 atgctcaagg ggccggaact gtataatccc ttgaattccg tagaagattc tactaatcgg
     4681 cgcgatactg tcttgcagaa tatggttgca gcaggatata ttgataaaaa ccaagaaacc
     4741 gaagctgctg aagttgatat gacttcgcaa ttgcacgata agtatgaagg aaaaatctca
     4801 gattaccgtt acccctctta ttttgatgcg gtggttaatg aagctgtttc caagtataat
     4861 ctaacagagg aagagattgt caataatggc taccgcattt acacagagct ggaccaaaac
     4921 taccaagcaa atatgcagat tgtttatgaa aacacatcgc tatttccgag ggcagaggat
     4981 ggaacgtttg ctcaatcagg aagtgtagct ctcgaaccga aaacaggggg agttcgtgga
     5041 gttgtcggtc aagttgctga caatgataaa actggattcc ggaatttcaa ctatgcaacc
     5101 caatcaaagc gtagtcctgg ttctacaatt aagcctttag ttgtttatac gccagcagtt
     5161 gaagcaggct gggctttgaa taagcagttg gataaccata ccatgcagta tgacagctat
     5221 aaggttgata actatgcagg gatcaaaacg agtcgagaag ttcctatgta tcaagccttg
     5281 gcagaatcgc ttaatctacc tgctgttgcc actgttaatg atttgggtgt cgacaaggct
     5341 tttgaggcag gcgaaaaatt cggactcaac atggaaaagg tcgaccgtgt tcttggtgtc
     5401 gccttgggaa gcggtgttga aaccaaccct cttcaaatgg ctcaagcata cgctgccttt
     5461 gcaaatgaag gtttaatgcc tgaagctcat tttattagta gaattgaaaa tgctagtgga
     5521 caagttattg cgagtcataa aaattcacaa aaacgggtga ttgataagtc tgtagctgac
     5581 aagatgacca gtatgatgtt ggggactttc accaacggta ccggtattag ttcatcgcct
     5641 gcagactatg tcatggcagg gaaaactgga acaactgaag cagttttcaa tccggagtac
     5701 acaagtgacc agtgggtaat tggttatact ccggatgtag tgattagcca ctggcttggc
     5761 tttccgacca ctgatgaaaa tcactatcta gctggctcta cttcaaacgg tgcagctcat
     5821 gtctttagaa acattgccaa taccatttta ccttatacgc caggaagtac ctttacggtt
     5881 gaaaatgctt ataagcaaaa tggaattgca ccagccaata caaaaagaca agtacaaacc
     5941 aatgataata gccagacaga tgataatttg tctgatattc gagggcgtgc gcaaagtcta
     6001 gtagatgagg ctagccgggc tatctcagat gcgaagatta aggaaaaggc tcaaacaata
     6061 tgggattcga tagtcaatct atttcgctaa gatgcttgtc aaagcctagc tttcttgtta
     6121 taatggataa gatggaggcg ttatggcact aaaaaaagca agcctagctt gtgcggtttg
     6181 tggttcgaga aactattcaa tcaagatcag cggaaacccc aagcctacac gactagaagt
     6241 aaataaattt tgtaagcatt gtggcaagta cactacacac agagaaacga gataggagag
     6301 agcgatgcgt tttattggag atatttttag acttcttaaa gacacaacat ggccaactcg
     6361 caaggaaagc tggagagatt ttcgttctat catggaatac acagctttct ttgtagtaat
     6421 tatttacatt tttgaccagt tgattgtttc aggtttgatt cgatttatta acatttttta
     6481 gaagattagt ggagttaatt acactagaaa tcttctattt atgaaaggaa atatcatgga
     6541 tagttttgat aaaggatggt ttgttttaca aacttattct ggttatgaaa ataaggtgaa
     6601 agaaaatcta ttacaacgtg cacaaaccta caatatgttg gataatattc tacgcgttga
     6661 aattccaaca caaacagtgc aagttgaaaa aaatggaaag agaaaagaag tagaagaaaa
     6721 tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca gatgaagctt ggtttgttgt
     6781 tcgaaacaca ccaaatgtta caggatttgt cggatcacac gggaacagat caaaaccaac
     6841 tccattattg gaacaagaaa ttcgtgacat tttggtatct atgggacaaa ctgttcaaga
     6901 atttgatttc gatgttgaga ttggtcaaac tgtacgtatt attgatggtg cttttgcaga
     6961 ctacactggt aagattacag aaattgataa taacaaagtg aaaatgatta tctctatgtt
     7021 tggtaatgac acagttgcag aagtaaacct aaaccaaatc gcagaattat aa
//
LOCUS       DAVHSH010000076         7005 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000076 DAVHSH010000000
VERSION     DAVHSH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.077"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(114..389)
                     /locus_tag="VVR08_001915"
     CDS             complement(114..389)
                     /locus_tag="VVR08_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU6075759.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(495..1334)
                     /locus_tag="VVR08_001916"
     CDS             complement(495..1334)
                     /locus_tag="VVR08_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6075760.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1476..2324
                     /locus_tag="VVR08_001917"
     CDS             1476..2324
                     /locus_tag="VVR08_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6075761.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2417..3334)
                     /locus_tag="VVR08_001918"
     CDS             complement(2417..3334)
                     /locus_tag="VVR08_001918"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU6075762.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWY"
     gene            3769..3975
                     /locus_tag="VVR08_001919"
     CDS             3769..3975
                     /locus_tag="VVR08_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1980 domain-containing protein"
                     /protein_id="HEU6075763.1"
                     /translation="MTAFQQLPSSVLQTGLFFSPSVSLDSQTVSAKEYLFPYQKERAQ
                     TTQTSEGTTSQYLKPDSSFYSQLK"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VVR08_001920"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VVR08_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU6075764.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VVR08_001921"
     CDS             complement(4596..4940)
                     /locus_tag="VVR08_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU6075765.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VVR08_001922"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VVR08_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU6075766.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5307..5394)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5489..6088)
                     /locus_tag="VVR08_001923"
     CDS             complement(5489..6088)
                     /locus_tag="VVR08_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU6075767.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6559..6858
                     /locus_tag="VVR08_001924"
     CDS             6559..6858
                     /locus_tag="VVR08_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU6075768.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2214 a         1420 c         1157 g         2214 t
ORIGIN      
        1 acaatatttt cggaacattc aactttttaa ctctatttat tactagattt cataattaaa
       61 aagcctactg accaagctag aaagcttgat acaataggct ttttaaagac tgattattta
      121 acagcgtctt taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc
      181 atttctttac cagtttgtgg gttgcgacct ttacgttctg cgcgctcacg aacttcaaag
      241 ttaccaaaac cgatcaattg aactttttca ccagctgcaa gatagtcagc tactgctgca
      301 aatacagctt caactgctgc tgctgagtct ttcttagtca attctgtagc ttctgctact
      361 ttagcgatca aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta
      421 acaaatataa tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc
      481 attttattta ttttttagga gtggtaacgt atcaaaatag cccaagcgtt ctcacccgtg
      541 tgagtttgaa taatggaacc cgtttccaaa acagaaattg gcttttcaac ataagcttgt
      601 aagctttctt tcatctcttt tgcccaatca tcactaccag aatatgaaat tccaatctct
      661 gctacagcac gttcagaaag cgatgttatc aactcatcta accatttttt aaatgtttta
      721 gttccacgac ctttaaccat tggctgcaat tcatggtctt tcatttgcat gacaacacgg
      781 atattgagaa gggagctcaa caagccagtt acacggccaa ttcgtccacc tttgacaaga
      841 ttttccaaag ttgaaacacc aatataaagc tctgtatggt ttttaacctc ttctacatga
      901 gataaaattg cctccatatc tttaccttct tgagctaact tcgcagcctc aacaacttgg
      961 aatttcaggg cttggtcagt gaaggaacta tcaacaacag tcacatctgc agtagatagg
     1021 ctagcacctt ggcgtgctgc ttctaccgta cccgaaagag catgggacat atgaatagca
     1081 agaatctggc caccatcttt gcataggtct tcaaaaatct cagcaaagac acctacaggt
     1141 ggctgacttg ttttcggaag attcttactt tcttgcatca actgaagaaa tttaccttct
     1201 tctttcaaat ccgcatcaga ataaacaaca ttatcaatca ttacagataa tggaacaatt
     1261 gtaatatcta attgctttac tagttcaggt tcaatagtaa cagatgaatc ggttacaatc
     1321 ttaatttttg tcatagtatc aatctttcta ttttaggatt cagattggtt tccttacttc
     1381 taattatatc aaaaaaaaga ttaaaaatcc taatggagtc aatcaaattt tccgtaaaat
     1441 ttgatataat caacttataa gaaaagaggt gtcctatgat taaaaaaatt taccccattt
     1501 ttaccatttt actaggtgct gctatttatg cttttggact gacttatttt gtagttcccc
     1561 atcatctctt tgaaggaggg gcgacaggca ttaccctcat caccttttat ctttttaaaa
     1621 tccctgtttc cctcatgaac ctgctgatta atattcccct tttcatccta gcttggaaga
     1681 tctttggagc caaatccctc tattctagtt tactaggaac cttagctttg tccgcctggt
     1741 tagctttttt tgagcatatt ccccttcata ttgatcttca aggtgattta ctaatcacag
     1801 cccttatagc gggaatccta ttgggaattg gccttggaat tatttttaat gctggaggta
     1861 caactggcgg aactgatatt ctagctcgta ttctcaacaa atacactcat atatccatag
     1921 gaaaactgct ctttatctta gatttttgta ttctcatgtt gattctccta atcttcaagg
     1981 atttgagatt ggtttcctac acgcttttgt ttgattttat tgtttctcgt gttattgatt
     2041 tgattggtga aggaggatat gccggcaaag gctttatgat tatcacaaaa cgtcctgacc
     2101 aacttgctaa ggcgattaat gatgacctcg gaagaggtgt tacttttatt tctggtcaag
     2161 gctactatag taaagaaaat ttgaaaatca tctactgtat tgtcggaaga aatgaaattg
     2221 tgaaaacgaa ggaaatgatt catcgaatcg atcctcaagc ctttataact attacagaag
     2281 cccatgaaat cctaggagaa ggcttcacct ttgaaaaaga ataaaaagag gtaatgtcgt
     2341 gacctcaaaa gttagactaa atcatctatc ttttgggtta cagacaacct cttttttatt
     2401 ttatttactc aagctcttaa taccaattcc gagttacttc ttcatcagcc tttaactgat
     2461 ccactaattg gtcaactgag tcaaatttgg tcatatctcg aatgcgatca agccaataaa
     2521 ccatgacggt ttccccataa atatcttgat taaaatcaaa aatattgact tcaaaacgtg
     2581 cttcttctcc atcaaaggtc acatttttcc cgacactagc catagcacga tacttctgtc
     2641 tttgaatctc aacatcaaca acataaacgc catctgctgg catataagta cggtctaaaa
     2701 gcactaaatt cgctgtcgga taaccaattg tacgaccacg agcattacca tgaaccacca
     2761 tacctcttga tggaagcggt gcccccaaaa gttttcctgc ttctttcaca tttccatcta
     2821 aaatagcttg acggatacga gttgaactaa tctttccttt ctcatcttct acaggtggaa
     2881 caatgataac ttctccatca aagtaatcct ttaaatcttc tgctgttttt ttgtcagaac
     2941 caaatgtata atcaaaacct gcaacaataa ttttggcatt catagccttg atataagttg
     3001 caaagaattc ttgtgcagtg agactagcga attgactact aaaatcaagg agatataatt
     3061 cttctacacc ttcgcgcttt aattttcttt cacgttcagc agggttcaaa atatgcaaaa
     3121 acaaatctgg atgataaggc tctaaagcga tctttggaga ttcattaaag gtcataacga
     3181 cgataggcaa caaatccttt ctcgcagcct tgttggcaac acgaaataat tcttgatgcc
     3241 ccttatgtat gccatcaaaa tagccgagaa caacgactga atcagatggt gtgccaatat
     3301 ctttttggtt ttttatagga atagtaataa tcataaaata attatatcat agcgatagct
     3361 atttctggaa cagaaaatct gaaatgttgt ttttttcaca tgaagtgtac ctgttttcaa
     3421 aaagcacttt attctatcgt tgcttaacta tgaactttgc aatattcttc tcaaaaactt
     3481 gtaggacatc ttcaaaattt tgcaaggagt gattagactt gttcggtaac cataaagtgt
     3541 catactatgc ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta
     3601 attggtgccg aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa
     3661 aatgagacaa cttgggcaag atgtttgaag aatttcctaa actccctgat ttgaagcaag
     3721 tcactttccc tgatgacaaa aaaagccaaa gcagtaaaga aaaactagat gactgctttc
     3781 caacaacttc catctagtgt gcttcagact gggctatttt tctctccatc tgttagcttg
     3841 gattctcaga ccgtttcagc taaagaatat cttttccctt atcagaagga acgggctcaa
     3901 accactcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagtttttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg gtatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt ttcgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaagagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt ttgtgaagac tcgcctagca tcgtgggaca
     5341 aaccacttaa acttgaataa tcaagcaacg atgttcgtgc ggttgcacag gatcgtgcat
     5401 agtcaactct tcaagtgtag catatttcct attttcttac aagtaataac acctaaaatc
     5461 aagctttttc ttttactttt ttctgccact aggcaaaaag catactgaga taaaaaatgc
     5521 tcatcataat aggaacacca agaatggtct tttcatgata gaaaatcgtc aaatagactg
     5581 aaaagacaac gccaaggaca aaactactaa gcaggctaac aaatatgaac ccttcacgca
     5641 aaaaaggagt gtgcttagtt cggaaataat ctccaaaagc tagcattgtt cgtttgatat
     5701 tccctgtcat aaaggcatta ttgtaggcaa tacccgaaac ctcaccaaaa gcagttgtca
     5761 ccagtcccat acagaaggcc aagggcggca ctagatagat attatctaca gtttgtggca
     5821 caaaaccaat aattattgat aggattgcta aaggaatcaa ggacagaata gattttttca
     5881 caattctcaa tttttcctta taaatcgtta ataaaaagac tcccatcata aacgctatta
     5941 aggttaaaag cttatcccta atatccgaaa cattattttg tatgagctct accgaaagaa
     6001 agacaacatt tccagcttgt ccagctacaa gggtattccc gcgaacaata aaagtgtaag
     6061 catccacata tccagcacaa aacgtcaaaa aagtgctaac cttttagact gacgtgatat
     6121 ttttcttata ggtaataacc tcattttccc tcccattgta ttttctctta gaaatattgt
     6181 accattttct ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat
     6241 aataatagac aactatttat ccaaaaatag atagaggtaa catgtttgca aacaaagcat
     6301 acgaaccttt agtaaaatca tttccatgaa actagaatag agcccctctt agcaaaaatc
     6361 attattttaa tttatttcta atcactcctt gacataaata actctcacca ataaaagact
     6421 atgtcttaaa aaaatggtat aataaaatca atacttggac ttgatggcta tgctactaat
     6481 aacaattagg agagaaaatc aggcacttgt taacaacaag gattatcccc ttgagatgaa
     6541 aggaacttta gaaatcttat gatgaacatg caaaacatga tgcgtcaagc acaaaaactt
     6601 caaaaacaaa tggaacaaag ccaagctgaa cttgctgcta tgcaatttgt tggcaaatct
     6661 gctcaagatc ttgtccaagc aaccttaact ggcgataaga aagttgtcag cattgatttc
     6721 aatccagctg tcgttgaccc agaagacctt gagactcttt ctgatatgac cgttcaagcc
     6781 atcaactctg ctcttgaaca aatcgatgaa actactaaga aaaaactggg tgctttcgct
     6841 gggaaattgc cattctaaaa acaaggagct agaacaatgc ttgtcgataa caaaggctaa
     6901 gaaaggtgca aaaattataa aaaacgcata gtatcaagca acctaaaact ttgggctcta
     6961 taatatttgt agtgggtaaa tcccctatgg atattacgga gccta
//
LOCUS       DAVHSH010000077         6864 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000077 DAVHSH010000000
VERSION     DAVHSH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.078"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..88
                     /locus_tag="VVR08_001925"
     CDS             <1..88
                     /locus_tag="VVR08_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU6075769.1"
                     /translation="ETMAQQVIPKAAFGYIASGAEDTFASFQ"
     gene            216..1706
                     /gene="lysS"
                     /locus_tag="VVR08_001926"
     CDS             216..1706
                     /gene="lysS"
                     /locus_tag="VVR08_001926"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU6075770.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            2330..3466
                     /gene="lctO"
                     /locus_tag="VVR08_001927"
     CDS             2330..3466
                     /gene="lctO"
                     /locus_tag="VVR08_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU6075771.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKDEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      3720..3808
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4023..4691
                     /locus_tag="VVR08_001928"
     CDS             4023..4691
                     /locus_tag="VVR08_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU6075772.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(4841..4927)
                     /locus_tag="VVR08_001929"
                     /pseudo
     CDS             complement(4841..4927)
                     /locus_tag="VVR08_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            5018..5800
                     /gene="thiM"
                     /locus_tag="VVR08_001930"
     CDS             5018..5800
                     /gene="thiM"
                     /locus_tag="VVR08_001930"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6075773.1"
                     /translation="MTSLKLLKKKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            5802..6431
                     /locus_tag="VVR08_001931"
     CDS             5802..6431
                     /locus_tag="VVR08_001931"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6075774.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      6640..6728
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
BASE COUNT         2180 a         1167 c         1471 g         2046 t
ORIGIN      
        1 ggagacaatg gcgcaacaag ttattcctaa agcagcattt ggctatatcg ctagtggggc
       61 ggaagatact ttcgcttctt tccagtgatt ttagcgtcag gttcttttta gtttttaaag
      121 attatccgtg aatttcttac ttatttatga taaaatggga gtatcgcaaa aaatgactca
      181 tcgtattcaa ttttgagtaa aactaggagg atcccatgtc tacagaacat atggaagaac
      241 taaatgacca gcagatcgtt cgccgtgaaa aaatggctgc gctccgcgaa caaggaatcg
      301 atcctttcgg aaaacgtttt gaacgtactg caaattcaca agaattaaaa gataaatatg
      361 ccaacctcga taaagaacaa ttacacgata aaaacgaaac agctactatc gcaggacgct
      421 tggtaaccaa acgtggtaaa ggtaaagtgg ggtttgccca ccttcaagac cgcgaaggcc
      481 agattcagat ctatgttcgt aaggatgctg tcggtgaaga aaactacgaa atcttcaaaa
      541 aagcagacct tggtgacttc cttggtgtcg aaggtgaagt gatgcgtacg gatatgggag
      601 aactctctat caaggcaacc cacatcacac acttgtctaa ggctcttcgt cctcttcctg
      661 agaaattcca tggtttgaca gacgttgaaa caatttaccg taaacgttac cttgacttga
      721 tttctaaccg tgaaagcttt gaacgttttg tcactcgttc aaaaatcatc tctgaaatcc
      781 gtcgttacct tgaccaaaaa ggattccttg aagtggaaac acctgttctt cacaacgaag
      841 ccggtggtgc tgctgcccgt ccatttatca cccaccacaa tgcccaaaac attgacatgg
      901 tgcttcgtat cgcgactgag cttcacttaa aacgccttat cgtgggtggt atggaacgtg
      961 tctatgaaat tgggcgtatc ttccgtaacg aaggaatgga tgctactcat aaccctgagt
     1021 tcacttctat cgaagtttac caagcttatg cagacttcca agatatcatg gacttgacgg
     1081 aaggcattat ccaacatgct gctaaatcag ttaagggcga tggcccagtc aactatcaag
     1141 gtactgaaat caagattaac gaaccattta agcgtgttca tatggtggat gctatcagag
     1201 aaattactgg tgtcgatttc tggcaagaca tgactttgga agaagctaaa gctatcgctg
     1261 ctgagaagaa agttccagtt gagaaacact acactgaggt tggtcacatc atcaatgcct
     1321 tctttgaaga gtttgttgaa gaaactttaa tccaaccaac ctttgtctat ggacatccag
     1381 tagctgtatc tccactcgct aagaaaaatc ctgaagacca acgctttact gaccgtttcg
     1441 agctctttat catgactaag gagtacggta atgcctttac tgagctcaac gacccaatcg
     1501 accaacttag ccgttttgaa gcccaagcta aagccaaaga acttggtgat gatgaagcga
     1561 caggaatcga ctatgactac attgaagctc ttgaatacgg tatgccacca acaggtggtt
     1621 tgggaatcgg tatcgaccgt ctctgcatgc tcctcactga tacaacaact atccgtgatg
     1681 tattgctctt cccaacaatg aaataaattc ttatcctctg gctcttacca gaggattttt
     1741 ttattcaaaa agagactgaa tttaaggaga aaatgaagtg tagtgtattg aaattgaaat
     1801 agtacacttt gatttctaag acattgttag aaattggttt aaattcccta atcaatttgt
     1861 gcatgtttta tttcatttta cgatagtacg ctgaaacttt tcaaaaagta ctagaaattg
     1921 acttggattc cccaattgat ttgttcagat tcactataaa taaaaaatta ataagtggga
     1981 taggaagtta gcgtcaacta ggatagtatc ttgcttaaac agtatatatg ggactgatat
     2041 aagtccatag gtcctattag aggatgttct ggtgtcttat tcacttgttt tttatagtat
     2101 tagtagatag aatcagcaaa taaaaaagta gttcaaatgc ctggcagcaa aaaatctcaa
     2161 cgattcactt aatatagact aaggtttaga gtttaaggaa agtagggcta gtatattgta
     2221 tgaaaaaata agatggtttt taagcaaaac tcttgaaaat gattgaaaaa agagttatta
     2281 tagttgtata gtaaaaagca aacgcttact taatcgagga ggacagttta tgtcatacaa
     2341 aacaagcaat gcagaaggtc atgtagactt tatcaatacc tatgatttgg agccaatggc
     2401 gcaacaagtt attcctaaag cagcatttgg ctatatcgct agtggggcgg aagatacttt
     2461 cactttaaga gagaatatcc gcgcctttaa ccacaaactc atcgttcctc atacactttg
     2521 cgatgttgaa aatccaagta cagagattga atttgcaggt gaaaaactat cttcgccaat
     2581 cattatggca cctgttgcgg ctcataaatt ggcaaatgaa cagggggaag tggcgactgc
     2641 gcgtggtgtg catgagtttg gttctcttta tacaaccagt tcttactcta ctgttgacct
     2701 tccagagatt tctgaagccc ttcaagggac acctcattgg tttcaatttt actttagtaa
     2761 ggatgacggt atcaaccgcc acatcatgga ccgtgtgaag gatgaaggtt ataaagcgat
     2821 tgtcttgacg gcagatgcta ctgtaggggg gaatcgtgaa gtggataagc gtaatggttt
     2881 tgtcttccca gttggcatgc cgattgttga agaatacctg ccagaaggtg ctggtaaatc
     2941 aatggacttt gtttacaaat cagctaaaca acgcttgtct ccacgcgatg tagaatttat
     3001 cgctgaatac tctggtcttc ctgtgtatgt caagggacca caatgccgtg aggacgttga
     3061 acgttcgctt gctgcaggag cttctggtat ctgggtaacc aaccacggtg gtcgtcaaat
     3121 cgacggtgga ccagctgcct ttgactcgct tcaagaagtg gcagaagcag ttgatagacg
     3181 tgtgccgatt gtctttgact ctggtgttcg tcgtggtcaa cacgtcttta aagccttggc
     3241 ttcaggagca gacttggtag ctattggtcg cccggttatt tatggcttgg ctctcggtgg
     3301 tagtgtcggt gtgcgtcaag tctttgaaca cttgaatgcg gaattgaaga cagttatgca
     3361 attgtctgga gctcagacca ttgaagatgt caaacacttt aagctccgtc acaatccata
     3421 caacccaacc ttcccagttg accctcgtga cttaaaattg tattgataaa acagattgcc
     3481 tccactgaat gtggaggttt ttcttcgtgt attggaagaa taaatcgcta tcgaaaacca
     3541 tagtaaaatg gaataaaaac aggacaaatc aatcaggata tttaaatcga tttctaacaa
     3601 tgttttagaa gtagaggggt actattctag tttcaatcta ctatatataa agatattttt
     3661 cggttaaata tcttgctaag gctttcattt tttgctatac tggttcagta attaaataat
     3721 agagacattt ggggtgcttt aggctgagat aatacccatt gaacctgata cagttaagac
     3781 tggcgaaggg aaatgtgaac agttttttcg tatggtgaaa tgaacggtct aatcttgtaa
     3841 gtcaactcta attcttgatt gtaattggag ttttttgttt atataaactg gataggcttg
     3901 tttagttagc tctctgcaaa tactctcgat gtgttttaaa aggatcaagt ggaattacga
     3961 ttttgcttga tatttcttgg tgttttacta attactaaca agtaaagaga ggagaagtaa
     4021 atatggaaac acaagactat gcatttcagc caggtttgac tgttggagaa ttattaaaaa
     4081 gcagtcagaa ggattggcag gctgcaatca atcatcgttt tgttaaggaa ctttttgcgg
     4141 ggacaattga gaataaggtc ttaaaggact atctgattca agattatcac ttctttgatg
     4201 ccttcttatc catgctgggt gcctgcgtag ctcacgcaga taaacttgaa tccaagcttc
     4261 gttttgccaa gcaactaggc tttcttgaag cagatgaaga tggttatttc caaaaggctt
     4321 ttaaagagtt aaaagtagca gagaatgact atctagaagt gactttgcac cctgtaacaa
     4381 aagcctttca ggatctaatg tattcggcag tggcttcatc agactatgcc catcttttgg
     4441 ttatgctggt cattgcagaa ggtctctatt tagactgggg ttctaaagat ttggctctac
     4501 ctgaagtcta tattcattcg gaatggatca atctccacag aggtcctttc tttgcagagt
     4561 gggttcaatt tctggttgac gaactcaatc gtgtcggtaa aaatcgagaa gatttgacag
     4621 aacttcagca acgctggaat caagcagtcg ctttagaatt agcttttttt gatattggtt
     4681 acgatgtcta gagaaggctc atgatattta caaatttgat gaggtaatac tcttcgaaaa
     4741 tctcttcaaa ccacgtcagt ttcaccttgc cgtaggtatg gttactgact tcgtcagttc
     4801 tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agtcttatct acaggttcaa
     4861 agcagtgttt tgagcaatct gcggttagct tcctagtttg ctctttgatt ttcattgagt
     4921 ataaatcatt caacgtaaat gaaaaaaatt tcttaacgaa agatagagat aaatcgaaat
     4981 cagtagatcg tataaagtga aaaggaagga tttcaatatg acaagtttaa aattattaaa
     5041 aaaaaaagca ccattggtca tttgtataac caatgatgta gtaaaaaatt tcacagcaaa
     5101 tggattagta gcactgggcg cctcaccagc catgagtgag tttccagcag atttagagga
     5161 tttgttaaag tatgctggtg gtttattaat aaacatagga acattgacag atgaaaattg
     5221 gaaattatac caagctgctc tgaaaattgc ggagaaatat aatgtcccag cagttttaga
     5281 tcctgtagcc tgtggagcag gagaatatag aaaaaaagta gcagatgatc taatcaacaa
     5341 ttataaacta gcagcgatta gaggaaatgc tggcgagatt gcctctttag taggaataga
     5401 tgtggcatct aaaggagtag atagtgcggg cgtagataat attgacgaaa ttgctctagc
     5461 agcaaatgag aagttcaata ttccaatagt agtaacaggt gaagtggatg ccattgctgt
     5521 taatggagaa gtggtaacga ttcataatgg tagtgctatg atgccgaaag tcattgggac
     5581 aggatgctta ttaggagctg tagtagcaag ttttatcgga ctggaaaaag gtcaagaatt
     5641 aaaatcatta gaaacagcaa tgttagttta caatatcgct ggagaaatgg cagaaaaacg
     5701 tccaaatgga catcttcctg ggacatttaa agttgaattt ataaatgcct tatacgagat
     5761 tacagatgaa gatgtaaagg aattcaaaag agtgaagtaa gatgtttcat aaagaattac
     5821 taaaactata ttttatttgt ggaacgacta cttgccaagg aaaaaatcta tatacagtcg
     5881 ttgaggaagc cttaaaaggt ggtataacct tatttcaatt tcgagaaaaa ggtgagggtg
     5941 ctttagaagg cttagaaaaa cttgagctag ctatccaaat taaagaactt tgtaaaaaat
     6001 acaatgttcc atttatcgtt aatgacgata tagatttagc aatggaaatt gacgccgatg
     6061 gcgtacatgt aggtcaagat gatattggtg ttgatgaaat tagaaaattg atgccagata
     6121 aaataattgg tctttctata agaaacgaag aagaatttca acaatcaaaa gttgaatatg
     6181 tagattatgt aggtgttggg cctgtatttg atacccagtc aaaagatgat gctggtggtg
     6241 ctataggtta tgaaggtctt gaattgatga gaaaactatt gccacaaatg cctttagttg
     6301 caattggtgg gatacagacg aaacatatta aagacattat aaagaccaat atggatggcg
     6361 tttcaatcat ttcggcaata tcgtatgcaa aaaatataga aaaaactgtt cgggaaatga
     6421 gtgaacaata gatatctatc cttggattct aagtaagtag gattttcctt ttttaaaaag
     6481 ctatgtccag attcagcttg aatggctaat tcatcaaaca ggtcatttgt tttttgcaaa
     6541 agaaagatct gctgtctttg tgagtgcaag gctgtatttc cagttcaatt tcttgaacta
     6601 gtataaaatg tgtgttataa taatcacata attaaataat aaagacattt ggggtgcttt
     6661 aggctgagat gatacccatt gaacctgata cagttaagac tggcgaaggg aaatgtgaaa
     6721 tgtttttttc gtatgtcgaa aagaactgtc taatcttgta agctgaactc taattcgtat
     6781 ctgtaattag agttttttct tttacgaaac tggatgaaga tgatacagta gattgaaata
     6841 agatgcgaac aaatcaatta gaaa
//
LOCUS       DAVHSH010000078         6756 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000078 DAVHSH010000000
VERSION     DAVHSH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.079"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            400..780
                     /locus_tag="VVR08_001932"
     CDS             400..780
                     /locus_tag="VVR08_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEU6075775.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(1181..2044)
                     /locus_tag="VVR08_001933"
     CDS             complement(1181..2044)
                     /locus_tag="VVR08_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6075776.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEIYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            2510..2848
                     /locus_tag="VVR08_001934"
     CDS             2510..2848
                     /locus_tag="VVR08_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU6075777.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVLGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            2826..3320
                     /locus_tag="VVR08_001935"
     CDS             2826..3320
                     /locus_tag="VVR08_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075778.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGAYLSKSACQGICAALAMSSGT
                     FIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLALIFLIKICVDTTIKFLFIRLFD
                     TSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSVLLLFSNFSVPFIKEKEFELF
                     KNSK"
     gene            4455..4958
                     /locus_tag="VVR08_001936"
     CDS             4455..4958
                     /locus_tag="VVR08_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075779.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLCEFIGDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDRNKRSAVLGLRRDKSGVFKPVPLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            5244..>6756
                     /locus_tag="VVR08_001937"
     CDS             5244..>6756
                     /locus_tag="VVR08_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEU6075780.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASSPTVVRAEDAPVANQSKAEK
                     DYDAAVKKSEAAKKAYEEAKKKAEDAQKKYDEDQKKTEEKAENEKKAAADLNEATEVH
                     QKAYVRYFEIQRAKDSKKYKNNRDKYNKDLAEADQKIKDTKTVLDEKQSKFYAVRAVV
                     VPEAKELAVTKQKAEETKKGVEVAKEKYDKAAQEVEVAKKEVEAEEAELDKKVAELQN
                     KVADLEKEIADAEKTVADLEKEVAKLEKDVEGFKESDGEYAEFYLEAAEKDLATKKAK
                     LAEAKIKAATKKAELEPELEKAEAELENLLSTLDPEGKTQDELDKEAAEAELNKKVEA
                     LQNQVAELEEELSKLEDNLKDAETSNVEDYIKEGLEEAIATKQAELEKTQKELGAALN
                     ELGPDGDEEETPAPAPQPAPAPKPAPAPQPEKPAEQPKAEKPADQQAEEDYARRSEEE
                     YNRLTQQQPPKAEKPAPAPQPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT         2340 a          940 c         1369 g         2107 t
ORIGIN      
        1 gctataatct ttccatgggg ctggtcgata taatgtaagg gagcttgagt tgttagtgga
       61 ggataaaatg ttaagagtaa tagtagttat tcaatcttta gtaataatac tgcttgctgt
      121 tgctttatta ttatctcgga aaaactttga ttcgttaaat gttgttctta taatgatgat
      181 cgtatcacaa ttgttgttat tagtatattt gataaaatca gggaatcagt gattagctgt
      241 tatttgaatt aagtaaactg ttaagcttca agcagtaact ggttttaaat atttaaaata
      301 agataaagga aggaagtcta atttaggtaa ctaaacaaag cctgcgatca cttgttagga
      361 aaccatccta accatgctta ataaaaaagg agaaaataaa tggaactcgt attaccaaat
      421 aattatgttg ctcttgagca agaagagatg atgtatcttg atgggggtgg tgttggtcgt
      481 aactggtgga atagtagagg tagttttgca acagttctgg atgtagattt ggccatctat
      541 agtggtggtg caacaattta ttctgcttat gcgataaaaa aagctatctc agctaataga
      601 ggggctatta cgagaacatt acgtagttta ataattaaac atgtaggtag tgcagctggc
      661 catttagtca atactgcact aaacgttgca ctaactgtta ctggattttc actaggtgga
      721 gcaatcgcat atggggctga ttgggctgac ggtagcttag atggttatat ttttgcttaa
      781 aatgaaacat ttttttgcag gaattggtga aataaacttt gtaagttatt tattgtatat
      841 atgtgtagga atagcccctt tttttcacgt atatataata ggttctgaaa tgaattttgt
      901 gaaaatagtg ttatctattt tgggaattat atttgtttgt attttaacta ttgctcgaat
      961 ttataggact tttttctata aagaatagtt tgaacttgaa atgtatttaa aaacaagagg
     1021 ttggtagatt atcagcctct ttcttgtcgt tgaaaaagtg agatatattg acttttgaaa
     1081 aaaatgtcat aattgagttg ggataaacgt aaaagtcata ctttctcgtt aaatcgttcg
     1141 gcgattctat gaaaaggtcg aggagctccc tcgacttttt ttataatttc tttggttgat
     1201 aatgggtctc tacttctttt ttgagatgag acagcataga agtttcctcg gtcagctcca
     1261 gaagggagaa ccctttttgg ataagtttag aatcgtctgt acaaatccca atgcggacat
     1321 agcagatagc cagcctatcg tagcttttct tattcttggc gtcctccagt aaagtgtagc
     1381 agatttgctt acacatgttt ttatcttgat tgtatagata gagtgtggaa aggttgagca
     1441 ggattgctat tcgcaagtca tataaatgtt gatagttttt atagatttct aggcgttgca
     1501 atatttttcc agtgatgaga tggaggtatt caatgggaaa actgaaaaga atggtattga
     1561 ggatttttag atcactctca taccatgtat cttgtttttc aatttttctc caaagttttt
     1621 tgacaacctg ttctgcgtga tctgatagtt cccctgcccc gtgttgacgg atataaatga
     1681 caacttcaag catatctctg atttcttcta tagggagatc gtggtgggtc ttgaggtagt
     1741 cttggcattt ttgaaataaa ttgacaagat cgctggtccc gataatggaa cgcatattga
     1801 gataggtttg cataatctct gtgcgttgac ttggttgata aagttgacag atatattcaa
     1861 actcttcaaa actcatattg atttgacgga gaagaaattc catattttca tattttgggg
     1921 ttgtcttgcc actttcgatt tttgataagc tggttcttga gagaacaccc ccacagacct
     1981 cttcttgggt cagccccttt gactcacgta tttctttata gacctttccg aaatcataac
     2041 gcatgatttt ctcctttctg tgaaaaaagt taacaaataa taaaatcttg ttaaaaatat
     2101 tgtatcatag caatgtaaaa agtaaaaaag aaagtcgaaa taaatttgtg aaaaaagtta
     2161 acgtaatttt aaaatgagct taataagagg tatgatgtag gtagaaaata aagataggag
     2221 aaaaagtatg aataaaaaaa tattttgtat tctagtatgt attatatcat tgattagtct
     2281 ggccataatc tttccatggg gctggtcgat ataatgtaag ggagcttgag ttgttaaagg
     2341 aggcttagtc cttggacaaa aatctgctgt actacaatgc ttggaaagat atcaagaaca
     2401 aagaatgata cgattgaaaa taaactgatt caagaactac tgggcagtga ttgaggtttg
     2461 ggtgacatca aagaaaagtt agattaattc taaagaattg agtatttcta tgttaaaaaa
     2521 atatccttgt acgatgcaac atgatcagtc agattgtgct gcggcagttg tttcaacagt
     2581 tcttttatct tacaaaaagg aactatcaat catgaagatt cgggaaatta ttggtacaga
     2641 catgtatgga acgactgtca gtggtattgt tttaggtctg aataagttga attttacagt
     2701 aaaagctgtt cgagtagcac tggaagattt gactccaaaa ttaacatttc ctgcgattct
     2761 tcaagttaag aatgatttag gtcaaaatca ttttgtggta ttacatagta taaaggagaa
     2821 aataaatgga actcgtatta ccaaataatt atgttgctct tgagcaagag gagatgatgt
     2881 atcttgatgg gggggcttat ttaagcaaga gtgcttgtca aggaatttgc gcagctttag
     2941 ctatgagctc aggaactttt atagcattga ctggagctgc agttttaaca aaaaaactaa
     3001 taaactatat taaggttgga ggccttggag gttggcttat tggtgcagca gcaggtgtat
     3061 tggctcttat ctttttgata aaaatttgtg tagataccac gataaaattt ttattcatca
     3121 gattatttga cacaagtact ttaatgaaga ggagaatatt ttttcttttc gcattggatg
     3181 ttatagctta cttattttta ggatatcttt tagtgattca aaaagcaggc tatttgtttt
     3241 cggttttact tcttttttct aatttttcag ttccatttat caaagaaaag gaattcgaat
     3301 tatttaaaaa tagcaagtaa tagaaacata ggttaaatct tagaacggct taaaatcaga
     3361 tatgataaag ggaaatagtc ttatctaggt aactaagtgc tacaaacaca atcgaggatc
     3421 acttgttagg attacatttt aatcatgctt aataagaatg gagaattcct atggggattg
     3481 tattactctg aactttcgaa taccttagtt ctcgtgattt tgagctattc tagctttaga
     3541 atccttcaga atgtaaaatt ttaagcagtc aaagacttag aatagcctaa aaacatttat
     3601 tttatagcaa ttctaaactt agaattgctc atatatatgt atttgagctg ctcgatagtt
     3661 aggacagctc tattctgaga aatctgagct atcaatgctt cagaatagta tttcgccaat
     3721 ggtttttatt gaagaggtga ttgtgttatg atagtctaaa ataaaattga tttaatagag
     3781 taaatggaga atcgttacat gaaacatttt tttgcaggaa ttggtgagat aaaacttgtt
     3841 ggctacttat tgtatatatg tgtaggacta gcccctcttt ttcatatata tgtcataggt
     3901 tcggaactga gttttgtgaa aatagtgtta tctattttgg gagttatatt tgtaagtatg
     3961 ttaactattg ctcgaattta tcggactttt ctataaagaa tagtttggac ttgaactgta
     4021 tctaaaaaca gaggttggta gattatcagc ctctttcttg tcgttgaaaa gagtgagata
     4081 tattgacttt tgaaaaaaag atgtcataat tgagttggga taaacctaaa agtaatatag
     4141 tagattgaat ctggaatagt ccgttatgac tgttaaaata tttctagaaa ttaatttgac
     4201 tttcctaatc gatttgttca catcttgttt caatctacta tactttctcg ttaaaccgtt
     4261 cggcaattca tggtgacatg gacacatagt agtaagcaca ctatgtggct tggcagagct
     4321 aaaaactgtt cccttgcgat aagcctaata agcacaacat agggagttag agaagccgac
     4381 tctaatcaac cactttgggc aatagtgaga actgccctgt gcttttttat tttgaaaaaa
     4441 tatggagttt gtcgttgaaa ttacttgatt gtattttgga ctatcaagaa agattcaatg
     4501 gaaaaacatg tcaagtatca acgaattata agtatttaga gattttcaaa gtgaattttt
     4561 gcttgactga tttacatcat ttatttggct tacacaaaat cacacgagat tatgctagtc
     4621 aaacaaaacc tgctattcaa gctggtgttt ttattttaga agattttaga aatatcctat
     4681 tgtacaatga tgtaatcgaa aggatatctt tatgtgagtt tatcggcgat attttctatt
     4741 ctaaaataac aagttgttgc atcgtagcta aggatttatc taaaaatact atgaaattgg
     4801 acgtcatatt ttttgaggat agaaataaaa gatccgcagt tttaggttta cgaagagaca
     4861 aaagcggagt atttaaacca gttcccctac attttacaag cgctaagaaa tatgctaaag
     4921 ttcgtaaaac agatgtgaaa gaaatgaaat ggctataaag attgtccgca ggcttaagct
     4981 tgcgtttttt gttgtttaac gaaattaaaa aacaagctct ctcatcggaa atgtttttat
     5041 aggaatgaag gaagatgatg ctatgtttaa aaagagaatc gaaaagggca aaagtagtgt
     5101 ctttatcttt ttggagtaga agcttatgat atagaaattt gtaataaaaa tgtaatataa
     5161 aacatttgac aaatatttac ggggggagta tacttaatat aattatagtc taaaaatgac
     5221 tatcagaaaa gaggtaaatt tagatgaata agaaaaaaat gattttaaca agtctagcca
     5281 gcgtcgctat cttaggggct ggttttgttg cgtcttcgcc tactgttgta agagcagaag
     5341 acgctcctgt agctaaccag tctaaagctg agaaagacta tgatgcagca gtgaaaaaat
     5401 ctgaagctgc taagaaggct tacgaagaag ctaaaaagaa agcagaagac gctcagaaaa
     5461 aatatgatga ggatcagaag aaaactgaag agaaagccga aaatgaaaaa aaggcagcag
     5521 cagacttgaa cgaagccaca gaagtgcatc aaaaagcata tgtaaggtat tttgaaattc
     5581 aacgagcaaa agattcaaaa aaatataaaa ataatcgtga taagtacaat aaagatctcg
     5641 ctgaagcaga tcaaaaaata aaggatacaa aaacagtatt agatgaaaag caatctaaat
     5701 tttatgctgt aagagcagtt gtagttcctg aagcaaagga gttagctgtt actaaacaaa
     5761 aagcggaaga aactaaaaaa ggcgtcgaag tagctaagga gaaatatgat aaggcagctc
     5821 aagaggtaga agtagcgaag aaagaagtag aggcagaaga agctgagttg gataaaaaag
     5881 ttgctgaact tcaaaataaa gttgctgatt tagaaaaaga aatagctgat gctgaaaaaa
     5941 cggtagcaga tttagaaaaa gaagttgcta aacttgaaaa agatgtagaa ggtttcaaag
     6001 aatcagatgg tgaatatgcc gaattctacc ttgaagctgc tgaaaaagac ctagctacta
     6061 aaaaagctaa attagcagaa gctaaaatta aagctgctac taaaaaagct gaattagaac
     6121 ctgaattaga aaaagcagaa gctgaacttg aaaacctatt atctacacta gaccctgaag
     6181 gtaagactca ggatgaatta gataaagaag ctgctgaagc tgagttgaat aaaaaagttg
     6241 aagctcttca aaaccaagtt gctgaattag aagaagaact ttcaaaactt gaagataatc
     6301 ttaaagatgc tgaaacaagc aacgttgaag actacattaa agaaggttta gaagaagcta
     6361 tcgcgactaa acaagctgag ttagaaaaaa ctcaaaaaga gttaggtgca gctcttaatg
     6421 agttaggccc tgatggagat gaagaagaaa ctccagcgcc ggctcctcaa ccagctcctg
     6481 caccaaaacc agcgccggct cctcaaccag aaaaaccagc tgaacaacca aaagcagaaa
     6541 aaccagctga tcaacaagct gaagaagact atgctcgtag atcagaagaa gaatataacc
     6601 gcttgactca acagcaaccg ccaaaagcag aaaaaccagc tcctgcacca caaccagagc
     6661 aaccagctcc tgcaccaaaa acaggttgga aacaagaaaa cggtatgtgg tacttctaca
     6721 atactgatgg ttcaatggca acaggttggc tccaaa
//
LOCUS       DAVHSH010000079         6705 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000079 DAVHSH010000000
VERSION     DAVHSH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6705
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.080"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(64..327)
                     /locus_tag="VVR08_001938"
                     /pseudo
     CDS             complement(64..327)
                     /locus_tag="VVR08_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            521..2287
                     /gene="patB"
                     /locus_tag="VVR08_001939"
     CDS             521..2287
                     /gene="patB"
                     /locus_tag="VVR08_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU6075781.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKHTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2426..3115
                     /locus_tag="VVR08_001940"
     CDS             2426..3115
                     /locus_tag="VVR08_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6075782.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKHLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3119..3298
                     /locus_tag="VVR08_001941"
     CDS             3119..3298
                     /locus_tag="VVR08_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075783.1"
                     /translation="MEHLVVLFFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3285..4634
                     /locus_tag="VVR08_001942"
     CDS             3285..4634
                     /locus_tag="VVR08_001942"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU6075784.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEKIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4758..6218
                     /locus_tag="VVR08_001943"
     CDS             4758..6218
                     /locus_tag="VVR08_001943"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU6075785.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGTIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6232..6666
                     /locus_tag="VVR08_001944"
     CDS             6232..6666
                     /locus_tag="VVR08_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6075786.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT         2092 a         1294 c         1445 g         1874 t
ORIGIN      
        1 ttctaactta gtcttaaaag caggtgaaaa gtgagggcat gctttggcag cttgtatgag
       61 tacctaccgc agatgagggg aaccccgttt gaccattctt tctgctaaat caatctgacc
      121 tgactgataa atagaagaat ccagtccagc gaaagcttgt aattgagcag gattatcaaa
      181 ggcatgaata tttcgaatct cggctaaaat gaccgcccct aaacgattct caatcccagt
      241 aaccgtcgtg atgaccgagt tgaactcagc catcaagtca ttgacacatt tttccgcctt
      301 gtcaatgagc ctcttgtaat gtttgatgtt ttcattacac gagataaaac gtctatgcgt
      361 tatcaaactc attaccaatt aaaacaaatg tggttagatc ctttcggaaa ttgtcaagcg
      421 attggaggaa atgaactaat ccacagcggc ttattccaag tataccactt gggctttggc
      481 agtagctaac tgcgctaaat ataatataag gaggagtaaa atgaagacag ttcaattttt
      541 ttggcattat tttaaggtct acaagttctc atttgtagtt gtcatcctga tgattgttct
      601 ggcgactttt gcccaagccc tctttccagt cttttctgga caagcggtga cgcagctagc
      661 caatttagtt caagcttatc aaaatggcaa tccagaactt gtatggcaaa gcctatcagg
      721 aatcatggtc aatcttggcc tgctggtttt ggttctattt atctctagtg taatatacat
      781 gtgtctcatg acgcgcgtga ttgcagaatc gaccaacgag atgcgcaaag gcctctttgg
      841 taagcttgct cagttgacgg tttctttctt tgaccgtcga caagatggcg atatcctgtc
      901 tcattttacc agtgatttgg ataatatcct ccaagccttt aacgaaagct tgattcaggt
      961 catgagcaat attgttttat acattggtct gattcttgtc atgttttcga gaaatgtgac
     1021 gctggctctc atcaccattg ccagcacccc attggctttc cttatgctga ttttcatcgt
     1081 gaaaatggca cgcaaacaca ccaacctcca gcagaaagag gtagggaagc tcaacgccta
     1141 tatggatgag agcatctcag gccaaaaagc cgtgattgtg caaggaattc aagaggatat
     1201 gatggcagga tttcttgaac aaaatgagcg cgtgcgcaag gcaaccttta aaggaagaat
     1261 gttctcagga attcttttcc ctgtcatgaa tgggatgagc ctgattaata cagccatcgt
     1321 catctttgct ggttcggctg tacttttgaa tgataagtct attgaaacaa gtacagccct
     1381 aggtttgatt gttatgtttg cacaattttc acagcagtac taccagccta ttatccaagt
     1441 tgcagcgagt tggggaagcc ttcagttggc ctttactgga gctgaacgaa ttcaggaaat
     1501 gtttgatgca gaggaggaaa tccgacctga aaaggctcca accttcacta agttgcaaga
     1561 aagtgttgaa atcagtcata tcgatttttc atacttgcct gataaaccta ttttgaaaga
     1621 tgtcagcatt tctgccccta aaggccagat gacagcagtt gttgggccga caggttcagg
     1681 aaaaacgact attatgaacc tcatcaatcg cttttatgat gttgatgctg gtggtattta
     1741 ttttgatggt aaagacattc gtggctatga cttagatagt cttagaagca aggtgggaat
     1801 tgtattgcaa gattcggtct tgtttagcgg aacgattcga gacaatatcc gatttggtgt
     1861 gccagatgct agtcaggaaa tggttgaggt agcagcaaaa gcaacccaca ttcacgacta
     1921 tatcgaaagt ttgcctgata agtacgatac tcttattgat gatgaccaga gcatcttttc
     1981 aacagggcag aagcaattga tttcaatcgc tcgaaccctg atgacagatc cagaagttct
     2041 cattctcgat gaagcaactt caaacgtaga tacggtgaca gaaagcaaga ttcagcatgc
     2101 catggaggtg gttgtagcag gtagaactag tttcgtcatt gcccaccgct tgaaaaccat
     2161 tctcaatgca gatcagatta ttgtccttaa agatggagaa gtcattgaac gtggtaacca
     2221 ccatgaactt ttgaagctag gtggttttta ttcagaactc tatcacaatc aatttgtttt
     2281 cgaataagaa agaagttgtc ctatgtgggc agctttttct tgtccataaa aaatgtttat
     2341 cacagcctta aaaaaaacat attagacgaa agtcattttg agtgatatga taggactatc
     2401 gttagcattc gaaaggagag gcatcatggc tagaacggtt gtaggagttg ctgcaaatct
     2461 atgtcccgta gacgcagaag gcaaaatcat tcattcatct gtatcttgta gattcgcaga
     2521 gatcattcgt caagtcggtg gtctcccttt agtcattcct gttggtgatg agtcagttgt
     2581 acgtgattat gtggaaatga ttgacaaact cattttgaca ggaggccaaa atgttcatcc
     2641 tcagttttat ggagagaaaa agaccgtcga gagcgatgat tacaatctgg tccgtgacga
     2701 atttgaattg gcactcttga aggaagcgct tcgtcagaat aaaccaatta tggcaatctg
     2761 tcgcggtgtc caacttgtca atgttgcctt tggtggaacc ctcaatcaag aaatcgaagg
     2821 tcactggcaa ggactacctt tcgggacatc tcactctatt gagacagtag aaggaagcgt
     2881 ggtggctaag ctatttggga aagaaagtca ggtcaactca gtccatcgtc aaagcattaa
     2941 acatttggca cctaatttcc gtgtaactgc tattgattca agagaccaaa ctattgaagc
     3001 gattgagtct atcgacgagc accgcattat cggtttacag tggcatccag agtttctggt
     3061 taatgaagaa gatggcaatt tagaattatt tgagtattta ttgaatgaac tgtaacgatt
     3121 ggaacatctg gtcgttcttt tttttatttt ttcaaaattt ttagaatgtg gtattttacg
     3181 caaacgtttg aattctgata aaaattggag aaattcgaca aaaaaacttg aaaaaaacga
     3241 aggtaagcgt tatgatagaa aagaagaaat attggaggaa gaacatgtca catattaaat
     3301 ttgattattc aaaagtttta gacaaatttg ttgcaccaca tgaagtggaa tacatgcaat
     3361 cacaagtaac agcagcagat gaattgatcc gtaaaggaac tggtgctggt agcgacttct
     3421 tgggatggtt ggaccttcct gaaaaatacg atcgcgaaga atttgaccgc atcttgaaag
     3481 ctgctgagaa aatcaagtca gacagcgatg ttttggttgt gatcggtatt ggtggatctt
     3541 accttggtgc aaaagcagca atcgacttct tgaatcacca ttttgctaac ttgcaaacaa
     3601 aagaagaacg caaagctcca caaatccttt acgcaggaaa ctcaatctca tctacttacc
     3661 ttgctgactt ggtagagtat gttgcagaca aggacttctc agtaaacgta atttctaaat
     3721 caggtacaac aactgaacca gcgattgctt tccgtgtctt taaagaactc ttggttaaga
     3781 aatacggtca agaagaagct aacaagcgta tctatgcaac aactgaccgc caaaagggtg
     3841 ctgttaaggt tgaagcagac gctaacggtt ggggaacatt tgttgttcca gatgatatcg
     3901 gtggacgctt ctcagtattg acagccgttg gtttgcttcc aatcgcagca tcaggagctg
     3961 acatcaaagc tcttatggaa ggtgcgaatg cagctcgcaa agactacact tcagacaaaa
     4021 tctctgaaaa cgaagcttac caatacgcag ccgttcgtaa catcctttat cgtaaaggct
     4081 atgcaactga gatcttggta aactatgagc catcacttca atacttctca gaatggtgga
     4141 aacaattggc tggtgaatca gaaggaaaag accaaaaagg tatctaccca acttcagcca
     4201 acttctcaac tgacttgcac tcacttggtc aatttatcca agaaggaact cgtatcatgt
     4261 ttgaaacagt tgtccgtgtt gacaaacctc gtaaaaacgt gcttattcct actttggaag
     4321 aagaccttga cggacttggt taccttcaag gaaaagacgt tgactttgta aacaaaaaag
     4381 caactgacgg tgttcttctt gcccacacag atggtgatgt accaaacatg tatgtgactc
     4441 ttccagagca agacgctttc actcttggtt acactatata cttcttcgaa ttggcaattg
     4501 ccctttcagg ttacttgaat gctatcaacc catttgacca accaggtgtt gaagcttata
     4561 aacgtaacat gtttgccctt cttggaaaac caggatttga agaattgagc aaagaactta
     4621 acgcacgtct ataatagaag aaaagagtgg tttgcccact ctttttactc tctttatcca
     4681 tagaaattgg actcagccaa gacttgtgat ataatataga aagcaaaaag gcagacgcct
     4741 agataatagg agaaactatg tcaaaagata tccgcgtacg ttacgcacca agtccaacag
     4801 gactactaca catcggaaat gctcgtacag cattgtttaa ttacttgtat gcgcgccatc
     4861 atggtggaac atttctcatc cgtatcgaag atactgaccg taaacgccat gtcgaggatg
     4921 gtgaacgttc acaacttgaa aaccttcgct ggttaggcat ggattgggat gaaagtccag
     4981 aatcacatga gaattatcgc cagtctgagc gtttggactt gtatcaaaaa tacatcgacc
     5041 aactattagc tgaaggaaaa gcctacaaat cttacgttac agaagaagag ttggcagctg
     5101 aacgtgaacg tcaagaagta gctggcgaaa caccacgcta catcaatgaa taccttggta
     5161 tgagtgaaga agaaaaagca gcttacatcg cagaacgtga agcagcaggg accatcccaa
     5221 ctgttcgttt ggctgtcaat gagtcaggta tctacaagtg gcatgatatg gtcaaaggcg
     5281 atatcgaatt tgaaggtggc aatatcggtg gtgactgggt tatccaaaag aaagacggtt
     5341 acccaactta caactttgcc gttgttatcg atgaccacga tatgcaaatc tctcatgtta
     5401 tccgtggaga tgaccatatt gctaatacac caaaacagct tatggtctat gaagctcttg
     5461 gttgggaagc tccagagttc ggtcacatga ccttgattat caactctgag actggtaaga
     5521 agttatctaa acgtgatact aatacacttc aatttatcga agattaccga aagaaaggtt
     5581 accttccaga agcagtcttt aattttattg ctcttcttgg ttggaaccca ggtggtgaag
     5641 atgagatttt ctctcgtgaa gaactcatta aactttttga tgaaaaccgc ctcagcaagt
     5701 caccagcagc ctttgatcag aaaaaactag actggatgag caatgattat atcaagaatg
     5761 cagaccttga aaccatcttt gaaatggcaa aaccattctt agaggaagca ggccgtttga
     5821 ctgacaaggc tgaaaaatta gttgagctct ataaaccaca aatgaaatca gtagatgaga
     5881 ttatcccatt gacagatctt ttcttctcag atttcccaga attgacagaa gcagagcgcg
     5941 aagtcatgac gggtgaaaca gttccaacag ttcttgaagc attcaaagca aaacttgaag
     6001 cgatgacaga tgataaattt gtgacagaaa atatcttccc acaaattaaa gcagttcaaa
     6061 aagaaacagg tattaaaggg aaaaatcttt tcatgcctat tcgtatcgca gtttcaggcg
     6121 aaatgcatgg gccagaatta ccagatacaa ttttcttgct tggacgtgaa aaatcaattc
     6181 agcatatcga aaacatgcta aaagaaatct ctaaataaag aggatacaat aatggacatc
     6241 tgggaaaaga tgtacgaaga agcacagaaa ctatacaatc cacatgaagt atcagacttt
     6301 gtttatgcca atcatgttgt agctgcagta gaagcagaag atggacaaat atttacagga
     6361 ttctgtatgg agggaacctg tggtgttttc catctctgcg cagaacgggc ggccctcttc
     6421 aatatgtacc aattttcagg acaaactaag gttaagaaag tattagcctt tcgagataaa
     6481 ccaccttatg gtggaagttc agccatgcct tgcggtgctt gtagagaatt ccttttagag
     6541 cttaatgctg aaaataaaga tgcagaattc atgatggact ataatataag aaaaacagtt
     6601 aaagtcgcag aactaatccc ttattggtgg ggagaagaac gtgcttctaa gtttaatgag
     6661 caatagaaga gtcagtataa ttctggctct ttttactata agttt
//
LOCUS       DAVHSH010000080         6304 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000080 DAVHSH010000000
VERSION     DAVHSH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.081"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            199..411
                     /locus_tag="VVR08_001945"
     CDS             199..411
                     /locus_tag="VVR08_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075787.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            928..1137
                     /locus_tag="VVR08_001946"
     CDS             928..1137
                     /locus_tag="VVR08_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075788.1"
                     /translation="MFFAGIGEIHFLLFLLYLSMSASPIIGLVIGYTKINLINSIIIA
                     LGMILALILVLSRVYRKYFYRDDDD"
     gene            1294..2352
                     /locus_tag="VVR08_001947"
     CDS             1294..2352
                     /locus_tag="VVR08_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075789.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2666..3643
                     /locus_tag="VVR08_001948"
     CDS             2666..3643
                     /locus_tag="VVR08_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075790.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            4020..4394
                     /locus_tag="VVR08_001949"
     CDS             4020..4394
                     /locus_tag="VVR08_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU6075791.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4602..5504
                     /locus_tag="VVR08_001950"
     CDS             4602..5504
                     /locus_tag="VVR08_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075792.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWNIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5560..5913
                     /locus_tag="VVR08_001951"
     CDS             5560..5913
                     /locus_tag="VVR08_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6075793.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIS
                     GNPYPWDGFISATVR"
     gene            5910..>6304
                     /locus_tag="VVR08_001952"
     CDS             5910..>6304
                     /locus_tag="VVR08_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075794.1"
                     /translation="MNNVDKIRKIHIIICWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFATKLTNEYKKISQFRSKVSQSPWI"
BASE COUNT         2102 a          790 c         1100 g         2312 t
ORIGIN      
        1 tttatcagag aaaaagagta tgaattattt aaaaataaga aatgagatag atatggtagc
       61 tttattaaaa ctgagaataa agtttgggag atatttttat ttattttagg tgtgttgtta
      121 attgtaattt cattactaag tcccccaaaa attaaatttt ggaaatagag ttagtgagaa
      181 ggataggata atagtattat gttgattgtt ttaatttcag ttattgttgc attcctgtat
      241 cataaaatta cagagtatgt caacaacagg aaaattgata ttgttatttt tctatcattg
      301 ctgatttctc attttatttg gaattactat tttttaccaa ttgaaatatt gatagcaatc
      361 agtggagcaa atttactatt aagtttttta aaaaaattac agactaaata atattaatct
      421 gtgtaataca gtagctcggt cattagattc tattgaagat ataaattaaa aatgaggctg
      481 ggaaaaaact caatttgaaa atgagattga gtaaatcttt ctatctatat aacgtatatc
      541 atcaatattt ttgaacacct gataatatgc atttttctta ttttaaagat tttttgcctt
      601 tcttcatttc ttgaatgaat tggagagatg actttattta ggtgtttgac attactatag
      661 ataggattta gcagtactaa tatgaactca tattataggt gcagacttaa attttggaag
      721 caagctaaag gatatcttat ctaggtaact aagtgctata acaagatata ttggtggagt
      781 tagtatggca actattacta atgctcttaa tattgcggct actgttgctg aagtcttctc
      841 attaggagga gccattgcat atggtttaga tatcgtagac ggtaaatttg atgggtattt
      901 atgggcgtaa aactatagct atgaaacatt ttttttgcag gaattggtga aattcatttt
      961 ttgttatttt tattatatct aagcatgtct gctagtccaa ttattggact agtgattgga
     1021 tatactaaaa taaatctaat aaattctatt attatagctc ttggtatgat attggcatta
     1081 attttggtat tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt
     1141 ttttatcaat aatttgggct ccttgtcaac tgtagtgggt tgaataaaag ctaacgtctg
     1201 gggaagggtt taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt
     1261 gatgcattct tagtaaataa tatggtgttt taaatgaaag atgatcagaa atatttatta
     1321 gcgggacttt attcgcttct agttgcaata ttttattttc cattgattga ttccaagggg
     1381 atttttgtaa gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca
     1441 gtcattcata ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta
     1501 tatccattta cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca
     1561 gaaatggtga gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct
     1621 tacggactgt taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc
     1681 ctggctacca ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg
     1741 ttcatgttct cttacatatt gctatttgta caatcttatt tgggtagcaa taccgcttgg
     1801 attggaaata gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt
     1861 tatgtaaaag aaatatcatc tgcacgatac tcagaatact tgacatgtga atacaaaaac
     1921 cttacaccaa tcatattgat agctattttt gaaaatttgc ttgactccta cttgcttcag
     1981 aatcagagtg aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa
     2041 aaatatacta tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga
     2101 tttttgggaa tcatttacga taatgaagca ttaagagatt tgtcaaaaca atatttaaac
     2161 aaaaatattt cggaattaca agatggttct ttcgagggcg gtatacaaga tgctgttgcc
     2221 tctaaacaaa tagtagttat aaatgaattt atagcttgtt taaattccag atgcgtgcca
     2281 tcccaatatg atagattttt ttataaagat agaccttata ttttttccag aaagagtcct
     2341 attaaggggt gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac
     2401 tctagtatag ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg
     2461 ccagaaaaga tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa
     2521 ataagctatc ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg
     2581 acaagtagcg caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta
     2641 ttatttaaca atggaaagta gactaatgaa aaataagcgt tatttttttg acacaatttt
     2701 aataatttta ctgcttataa gcacgatatt ttgtgtcagc ccagtattta taaaattgga
     2761 catcttagga actccctctc atgccatctt aacctttgta ttggcgatac cgttattcta
     2821 tattttgtct caatgcttac atactttgct attactagtt tcctcaatct tttgtaaatt
     2881 aagaccaatt tatttttatt ttatatttgt gatcattata ggagctagga aatactatcg
     2941 aattctcttt caccaactaa tgggatttag tccaggaata gcagtgtttt ataaggagag
     3001 tcaaacaact aagaatctgt ttaaatttta ctacttcttg tactttacaa cactaatttc
     3061 atactatttt ttctttactt ttgtgtatga caaaccgttg cttttgcctc ttatttcatt
     3121 ttctattatc atagcattag tacaaaaact ttatagaatt gagaatcaac aattatttct
     3181 gttaaaatca aaggtactaa caatactgga atctaagaag aattgtgagt ttaatcttca
     3241 ggattatcat gaaatttgga aattgcaatc aaaatctgaa ttgccatgcg tggctttatc
     3301 ttatatcagt ttaatcaagc catatctttc agagagtgtg cgtgaacaaa ttgatttatt
     3361 agaagttaag cgatttaaaa aaataaatca tccaatatca ctttatggta tgttggatgt
     3421 tataaaatta aatctatatt tacggcatta taatgaaaaa aataaatatg aatcaatgtt
     3481 aaagaaaatt ttagaggtaa gaccagactt tgttttaatc gagcagaata ttgatgatag
     3541 tttaaatagc tcgcaaccat tatctttatc tttagccatt tcagaaatcc aacttttgct
     3601 tgaagtgtat atggggatca aacatgtttc aattaggaga taaaaccaga ataatatttg
     3661 ccattatagg ggcaagttgc atattagtca gtatgtatct tattccactt attaaaactg
     3721 agaataaatt ttgggaaata cttttattta tattaggtgt attgctaatt ggaattgcgt
     3781 tactaagtca aaaaaaataa attttgaaat agtattagtg agttcgcaat catttattgc
     3841 tagtggttta gaactgttaa gtttcaaaca ataattgatt ttaaacctta ggtaacctat
     3901 aaaaacaaat aaggtagaga aaggatatct tatctaggta gctaagtgat aaaaacacag
     3961 tcgtctatca cttgttagga aactatccta actatgctta ataaaaaagg agaaaataaa
     4021 tggaactcgt attaccaaat aattatgttg ctcttgagca agaagagatg atgtatcttg
     4081 atgggggatt ttctattctg agatggcctg ttgcaacagc cattaatata gcttttaatg
     4141 gtgttttagg tggaggagca atcagtctag ttagaaatta tattcgtaat tatggtttgc
     4201 ggcgagttac aagcgcaatt gctggagcag ctgcaagata tgttggggta cgagttgcaa
     4261 atagagtggc aggatttgca ctgtctgcta ttaatggatt tgcagcttgg atgtcaattg
     4321 gcgatgctat tacaacaatc tgggccaaca atgatgtaaa taggagagac cccaatttaa
     4381 acgccttgtg gtaactagat atgggtatta aaatggaaaa aatttttgtt attatttttt
     4441 ttgtatgtct atttatatca tccataactt ttttagccta tgattttgtt agcgaagaaa
     4501 taaaaaagtt gattatttgg attaatgtcg tttttttgat tttaatcata gcaatgataa
     4561 tttatccaaa attaagaaaa tgataaggac actgtaaaat tatgatacgt aaactaatca
     4621 tttttttatt aatgctccct ctttttgtct tgtggctaga gttgcatgtc ctagtgaata
     4681 acttactatt gaatctagaa tctccccttg attttgtgat tagtatgagt cttgctttct
     4741 gtagtttgat tttatcaaaa atagttttag acatactata cgcattgaaa gatttgtaca
     4801 agaaagaagc tcttattacg atttttcctt ttatttttat aggcaggaag aaagtaaatg
     4861 tgaggttctc gccctatttt tcattccatc gtaaaagttt gtcgcctgat gatttaagat
     4921 ctaggattat atggagtttt attcttgaaa ttgctattat cctagtattt attttaaaaa
     4981 ttccttttgt catcattatg cttactacaa tatttttttg gaatataatg gatatcaatc
     5041 atctcgtttt taataagacg gaatttcttt tcaatcaaaa taaatgggaa aaagaagatt
     5101 cgtttgaaag tgatttgaca aatacgttaa aggataaaat acaaaaatca gatctcagtt
     5161 attctgactt aatgtctctt cagctgtatg atgcgatgaa ccaatccacc tttttaacgg
     5221 atagtgaact ctttgaggat attctgagta aaattgaaga ttctcataac acccttctgt
     5281 gtacaggtct tgtcgagtta ctgctgtatg agatttctat tagtaacaat aacaactggc
     5341 aagaaaaggt tgataaaatt agaatacagc tcatcagaat aaatcaatta gattttttct
     5401 attatacaag ttggttaagg caaaattttg atttctgtat gaatagagag tatcataaaa
     5461 tgaaatctcg gaaattatta ctgagtaata aaaagatagt ttaagttcgt cctatttgta
     5521 aaacaaatga aacaatttca actaaggagg agaaaacaaa tggaacttgt attaccaaat
     5581 aattatgttg tgattgatga agaagaaatg atgtatcttg atgggggagc ttatttaagc
     5641 aagcgtgctt gtcaaggaat ttgcgcagct ttagctatga gttcaggaac ttttatagca
     5701 ttagctggag ctgcagtttt aaccaaaaaa ctaataaact atattaaggt tggaggtctt
     5761 ggaggctggc ttattggtgc agcagcaggt gtattggcta cagcagcagg gaaaatagct
     5821 tactgtattg gatatggtgt tcttaataga ggttgtgata ttagcgggaa cccttatcct
     5881 tgggatggat tcatatctgc gacagtaaga tgaataatgt agataagatt cgaaaaatac
     5941 atattatcat atgttggatg tatatatttt tatcattcag ggcgattata aatgacacgg
     6001 agtatttttt gcttattttt ttagctttta tctactcaat agtatcacta cctctatatt
     6061 ctgtgaaaaa taaaatagta tctatctgtc tagccataaa ttcgattctg ttaatcagtt
     6121 tccccatttt aatcaataaa tttttcccag aaagtttttt gacttatacc gtattaataa
     6181 gtgtttttat tacagagttg ataatttttc atttaattgg gaaagatttt gctactaaat
     6241 tgactaacga atataagaaa attagtcagt ttagaagcaa ggtgtctcaa tctccttgga
     6301 taaa
//
LOCUS       DAVHSH010000081         6214 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000081 DAVHSH010000000
VERSION     DAVHSH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6214
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.082"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            403..879
                     /locus_tag="VVR08_001953"
     CDS             403..879
                     /locus_tag="VVR08_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075795.1"
                     /translation="MSRTYINIRLAYETKYWLECIQEEVQKKLDALINEQDIEELESI
                     ITNKLEKKDSLLGAVSITTFFKVSSSSVIEKAYNETKNYTTSEWREIARQMNLAKVKQ
                     NMEIGTLTPRLYLDNNIISELEKYQFLFKSDDMIRQVRMSYVIKMVAFAYYKKLFA"
     gene            1050..1604
                     /locus_tag="VVR08_001954"
     CDS             1050..1604
                     /locus_tag="VVR08_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075796.1"
                     /translation="MPKLLETEKYSLDSIIDGGKLRMISKFCPDLHGLRYEFKTSDSI
                     TKEYCKKIRQALRDSDPEGKSGKKCMMRYTIDILNVWNTLCRTRDFITGSLKADDVID
                     GKTGIYFFDVNTSNVITDDVIENVKINHKSLVRNVDEENIESISKEIPKGTDMYYYVL
                     YRLGLNRIKYNYLVKALAGAIQKD"
     gene            1880..2257
                     /locus_tag="VVR08_001955"
                     /pseudo
     CDS             1880..2257
                     /locus_tag="VVR08_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
     gene            2251..2373
                     /locus_tag="VVR08_001956"
                     /pseudo
     CDS             2251..2373
                     /locus_tag="VVR08_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            2377..3510
                     /locus_tag="VVR08_001957"
     CDS             2377..3510
                     /locus_tag="VVR08_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU6075797.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYMTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            3551..3988
                     /locus_tag="VVR08_001958"
     CDS             3551..3988
                     /locus_tag="VVR08_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU6075798.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVTTDEE
                     KAVAYLHDVIEDTTLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKTNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRTKKKS"
     gene            4196..4432
                     /locus_tag="VVR08_001959"
     CDS             4196..4432
                     /locus_tag="VVR08_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU6075799.1"
                     /translation="MNNVVTTLISVQFSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKTISHEEMMRRYG"
     gene            4425..5156
                     /locus_tag="VVR08_001960"
     CDS             4425..5156
                     /locus_tag="VVR08_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU6075800.1"
                     /translation="MAKIYAISDIHGYLDEFIDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(5267..5350)
                     /locus_tag="VVR08_001961"
     tRNA            complement(5267..5350)
                     /locus_tag="VVR08_001961"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5314..5316),aa:Leu,seq:caa)
     gene            complement(5360..5431)
                     /locus_tag="VVR08_001962"
     tRNA            complement(5360..5431)
                     /locus_tag="VVR08_001962"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5397..5399),aa:Gln,seq:ttg)
     gene            complement(5445..5517)
                     /locus_tag="VVR08_001963"
     tRNA            complement(5445..5517)
                     /locus_tag="VVR08_001963"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5482..5484),aa:His,seq:gtg)
     gene            complement(5532..5602)
                     /locus_tag="VVR08_001964"
     tRNA            complement(5532..5602)
                     /locus_tag="VVR08_001964"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5568..5570),aa:Trp,seq:cca)
     gene            complement(5607..5687)
                     /locus_tag="VVR08_001965"
     tRNA            complement(5607..5687)
                     /locus_tag="VVR08_001965"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5651..5653),aa:Tyr,seq:gta)
     gene            complement(5700..5772)
                     /locus_tag="VVR08_001966"
     tRNA            complement(5700..5772)
                     /locus_tag="VVR08_001966"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5737..5739),aa:Phe,seq:gaa)
     gene            complement(5776..5849)
                     /locus_tag="VVR08_001967"
     tRNA            complement(5776..5849)
                     /locus_tag="VVR08_001967"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5813..5815),aa:Met,seq:cat)
     gene            complement(5860..5949)
                     /locus_tag="VVR08_001968"
     tRNA            complement(5860..5949)
                     /locus_tag="VVR08_001968"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5911..5913),aa:Ser,seq:tga)
     gene            complement(6032..6105)
                     /locus_tag="VVR08_001969"
     tRNA            complement(6032..6105)
                     /locus_tag="VVR08_001969"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6069..6071),aa:Ile,seq:gat)
     gene            complement(6140..6210)
                     /locus_tag="VVR08_001970"
     tRNA            complement(6140..6210)
                     /locus_tag="VVR08_001970"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6176..6178),aa:Gly,seq:tcc)
BASE COUNT         2304 a         1004 c         1097 g         1809 t
ORIGIN      
        1 attcctatct tggatttgat gccttatttc tttacttaaa ttttttaggt cttcaccatt
       61 acatagtttt tctccaatga gtttactaaa ggtaaaagac ttaataactt tcttgagact
      121 ttcttcaaac ttgccattta gaagcttcaa atagctttca aaatctgata tcactctcgt
      181 tttgacggtc tcaaagtctt cgtcttcagt aatttcataa ttgactgata tccaatatag
      241 cattttctat ctccttattt agttttatta ttactagttt attatatttt taatagaatg
      301 tcgcaattta attatataga atttaaattc aaaaatattg ttgacaaata gaaaatactg
      361 tgttaaaatg tctatataac agagacagtt ggaggtataa gaatgagtcg tacttatata
      421 aatataagac ttgcatacga aaccaagtat tggttagaat gtatacaaga agaggttcaa
      481 aaaaaattag atgctttaat taatgaacaa gatatagagg agttagaatc aatcatcact
      541 aataagttag aaaaaaaaga ttctctattg ggggctgttt ccataacaac ttttttcaag
      601 gtatcttctt caagcgtgat tgaaaaagcc tataacgaga caaaaaatta cactacttca
      661 gaatggcgag aaattgcaag gcaaatgaat ttggcaaaag ttaagcaaaa catggaaatt
      721 gggacgttaa cacctagatt atatttagat aataatatta tttcagaatt agagaagtat
      781 caatttttat tcaaaagtga tgatatgata aggcaggtaa ggatgagcta tgttattaaa
      841 atggtcgcat ttgcctacta taaaaaattg tttgcatgat ttataagctc gataataaga
      901 gcttataaaa atacaacctt tgtctgtgtt aacgagactt ttaaactttt taatcggaag
      961 gagaatattt tgataggagc gtcacctatt atttatttga caacattaaa taaaaactaa
     1021 tattaaaaaa atataaagga ggagcagaaa tgccaaaatt attagagact gaaaaataca
     1081 gtttagatag cattatagat ggagggaagc ttagaatgat ttctaagttt tgcccagact
     1141 tacatggctt gaggtacgaa ttcaaaacat cagactcaat tactaaagaa tattgtaaaa
     1201 aaatacgtca agctttaaga gattctgatc cagaaggaaa gagtggaaaa aaatgtatga
     1261 tgagatatac aatagatatt ttaaatgtat ggaacacgct atgtagaaca cgagatttta
     1321 taacggggag tttaaaagcg gatgatgtta tagatgggaa gacagggata tacttctttg
     1381 atgttaatac gtctaatgta attacggatg atgttataga aaatgttaaa attaatcaca
     1441 aaagcttagt acgaaatgtt gatgaagaaa atatagaaag tatttcaaaa gaaattccta
     1501 aaggcactga tatgtattat tatgttttgt atagattagg gttgaatagg attaagtata
     1561 attatttagt caaggctctg gcaggcgcaa tacagaagga ttaagaatat aattatataa
     1621 ttaaggggga gttttttctc cccttataga gatagtatta ttcttttggt atttggggta
     1681 tcgtttatca atctcatctt atagctaata aaaatagtct atgtttttag tgaaaaaaat
     1741 attattttaa ggagtggtga tatgtatata cttgtcacaa atgggaaaag ctacgtgact
     1801 ttcccttggt tgcgtgaaat agcttgcaga aattataaag gagaaactaa ggtgtttact
     1861 acaaaggaac tctataattt cctatattaa acgctttaac tatcacattt ttaataccaa
     1921 gaaaagtaaa ttaaaatata tagcagtatt agagaggcaa aaacgtaaag catggcatag
     1981 tcatattttg ctattcagtg ttccctatat tccacataag caattattag aactttgggg
     2041 gcatggagca aataaagttg acgttgacag caaagaaaat cgcggtcgat atgtcacaaa
     2101 gtattttgaa aaaggtattg gacaagaatt gttggaaaac ttcggaaagc aagcctattt
     2161 ttcatcacgc aacttgaaaa agcctgatga agataaattt tacacttatg aagattttaa
     2221 ctatgatagt tcagtcgtac tatatgaaac ggaatacaac tgataacccg aggctttaca
     2281 gtctatcaga acaagcgaat tggtactata cctgctacta ttgctaccga attactcggt
     2341 tttgatgttc aaaacagtac cctcaaggag taaaatatgg caattagaaa aggtaaagac
     2401 ggtaattggg tagttgatat tagcaacggt tttgacccaa taacactaaa gcaacgtaga
     2461 cttgtcagaa agggatatat gacgaaaaaa gaagctattg aagcagaaca ctacttacga
     2521 agtgtagagt taaaagaacg cttctatggg gctaaaataa ctatctccat actatatgaa
     2581 ctacttaagg aagaagatag cataaatcat cgaaaagcaa gctatatcaa tacacaagat
     2641 aataattaca acaaacacat caaagattat ttttctatgg tcgataatgt cggaaaacta
     2701 acctatgaag acatctacca atttagagaa catcttaggc aaaaagtagc taaaaattct
     2761 gataaaccgt taagcacaaa tactattaac aaaatcatga ttttactcaa aaaaattttt
     2821 gatgttggtt tgcgaaaagg ctattactcc tccaatccag caaaattgat aaaaaagttg
     2881 ccaattgaaa aaacaaaaat gcaattttgg acagtcaaag aatttcagaa gtttttgaca
     2941 ctatttgaac ccgaagaata caatatcaaa ctactcttta ctgttctatt ctttacagga
     3001 ttaagacttg gggaagctct tgctctaaca tggcaagaca tcgacttttc aagtaataca
     3061 attcatatca cgaaatctgt ctatgttaat aaaggagtaa ctcatatcag cacaacaaaa
     3121 actaaagcag gaacaagaag aattgttatc aataaaaaat taagccaaga attacaagat
     3181 tgggaaaagc gacaaaaaca tctattagag caatttacca acaatagcct aacattacaa
     3241 gtgtttcaaa atagtcctat cacaattaca aaaaatgcta ttgaaaagca gtacaagaaa
     3301 atcattgaac gtgatagtac actaaaaaag atacgcatac acgattttag gcactcacac
     3361 gcttccctgc tgattaacca aggggaagat tatctagttg taaaagagcg actaggacat
     3421 gcttctataa caaccacgat tgatacctac tctcacttgt acccaagtaa gcaaaaggat
     3481 ttagctgata aactagatga tttactataa agtaattgag ttttataaat ggaaagttta
     3541 taattaaatc atggatacat cacaagtaat aaaagcacat gaagtagcta aaaaagcaca
     3601 ctttggacaa attgatagag caggaattga ctacattaaa caccctgaaa cagtagctag
     3661 ttttgtcaca actgatgaag agaaagctgt cgcctatcta catgatgtaa ttgaagatac
     3721 tacactaacc ctactagacc taaaaaagga aggtttttca aaaaacatta tagaagcagt
     3781 cgatatactc acaaagaaaa aaggacaaga ttatcaatct tatctcaatc tagtaaagac
     3841 aaatgaactt gctagagttg taaaattggc ggatttacgg cataattcag atttaaccag
     3901 actaccatta attactgaaa aagacttaga gagaaataag aaatacagtt ctgctattag
     3961 atttttaaga acaaagaaaa aaagttagta actaaactat aaaaatttat aaagagaaaa
     4021 caaggcttat aaactttgtc tttattacta tcttggcggt cagtctcgaa ctggcacatc
     4081 cttgcagata ctacaatttt attaaaataa atactataca aagtgaaatt ttttattgag
     4141 aaacttttag actaggagta taatgtatct aaaataacta ttaggtggct gttatatgaa
     4201 taatgttgtt actacactaa tttctgttca atttagtcaa gagttaaatt ctttattaaa
     4261 tgctattgtt gaagaaaata atacaacaaa gactgacttt attagacaag ctgttataga
     4321 gaaaattgaa gatatgtatg atattaaggt cgctgatgaa gcttataaaa aatgggttga
     4381 atgtggcaaa aaaactatct cacatgaaga aatgatgaga cgctatggct aaaatatacg
     4441 caatatctga tatacatgga tacttggatg aattcataga cgctctcaat aaagtaaatt
     4501 taaacgataa agataatcgc ctatttttac taggagatta tcttgataat ggacttcaat
     4561 cttttcaagt catttccaaa ataatcgaac ttgaggagat ttatcctaat caaattatta
     4621 ctcttctagg gaaccatgaa gaatggtttt atgattggtt gattttagat aagcctactg
     4681 cttcagcatt tccagaaaca ataaaaagct tcttctctcc agaggaattg aactatattt
     4741 ttaaatcgaa tgctaacaac tttgaaacag gtgttagaaa tgaaattaaa aataatatca
     4801 aattcaaccc atttataaac tggtttaaaa agcgatatag ggataaacgc tattatgaaa
     4861 ctgataccca aatttttgtt catgcaggca ttgatgaaga agcaggaatg ctttggaaag
     4921 aactaacgag ttcaaagata tttacaaaca aatttccaat taccactggt agatttcata
     4981 aagctattat ttcgggccat attgcttctt gggaagtagc taaagataga agatacctag
     5041 gtaagattta ctatgatagt aaaagtcatt acttaattga tggagatgta acgaatagca
     5101 aaacaatacc tgttctttgc tatgatacaa ttacccaaaa atatcacttt ctataacttt
     5161 tagtcatgtg cttttatatg aaattagtaa ttattagtaa caattccaag aaatttctta
     5221 tgacataaca aaaagacaag gcttagaaac cttgtctttt caactatacc ggcggccggg
     5281 gtcgaaccgg cacgtccttg cggacactgg attttgagtc cagcgcgtct gccaattccg
     5341 ccacgccggc aaatagtaac tggggtagct ggattcgaac caacgcatga gggagtcaaa
     5401 gtcccttgcc ttaccgcttg gctatacccc aataatataa aataggcgag tgatggggat
     5461 cgaacccacg catgccagag ccacaatctg gtgtgttaac cacttcacca cacccgccat
     5521 aattctatta acacgggcag taggaattga acccacactg aaggttttgg agaccttagt
     5581 tctaccttta aactatgccc gtaaaatgga aggggaggga ttcgaacccc cgaacccgaa
     5641 ggagcggatt tacagtccgc cgcgtttagc ctcttcgcta cccttccaaa atatataaat
     5701 ggcgcgagac ggaatcgaac cgccgacaca tggagcttca atccattgct ctaccaactg
     5761 agctaccgag ccttattgcg ggagcaggat ttgaacctac gaccttcggg ttatgagccc
     5821 gacgagctac cgtgctgctc catcccgcgt taatataaaa ggaggatgtg ggattcgaac
     5881 ccacgcacgc ttttacacgc ctgacggttt tcaagaccgt tcccttcagc cggacttggg
     5941 taatcctcca aaatagttta tacgggaaca agcccgtgtc ctcttagtga acagataata
     6001 ttccaatccc ctagtaatgg actaaacact atgggcacga gtggactcga accaccgacc
     6061 tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtt aaaaacttgg
     6121 tacaaagaac aaagttcaaa gcgggtgacg agaatcgaac tcgcgacaac agcttggaag
     6181 gctgtagttt taccactaaa ctacacccgc taaa
//
LOCUS       DAVHSH010000082         6118 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000082 DAVHSH010000000
VERSION     DAVHSH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.083"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            222..422
                     /locus_tag="VVR08_001971"
     CDS             222..422
                     /locus_tag="VVR08_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075801.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VVR08_001972"
     CDS             447..863
                     /locus_tag="VVR08_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075802.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRHKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VVR08_001973"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VVR08_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6075803.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VVR08_001974"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VVR08_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU6075804.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGQEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGHKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2743..4134
                     /locus_tag="VVR08_001975"
     CDS             2743..4134
                     /locus_tag="VVR08_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU6075805.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4277..5194
                     /gene="adcAII"
                     /locus_tag="VVR08_001976"
     CDS             4277..5194
                     /gene="adcAII"
                     /locus_tag="VVR08_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU6075806.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAI
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5202..>6118
                     /gene="phtB"
                     /locus_tag="VVR08_001977"
     CDS             5202..>6118
                     /gene="phtB"
                     /locus_tag="VVR08_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU6075807.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRT"
BASE COUNT         1871 a         1107 c         1287 g         1853 t
ORIGIN      
        1 ttggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tattaaaacg
       61 aaataagaat aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtccatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccaga tccaagctca gctccgactc aagatcctag agtggtagta agcgcttcgg
      241 ctagctcaac gagcccacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacac ttgaaagctt tggcaacagt atctgatccg aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cataagaaag
      661 agtcagaaat ccagcaatta agcacggaat taatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagactta aaagacattt
      901 tcgttcacaa aagcagcgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatggca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggcgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtatt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtcaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt tctgttggaa aagatgctcc agactttaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggaca taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttggt aacttctaaa actaacttcc agtttcccac aacttagctt ttagtatgag
     2461 aaaaacgcgt gacatcagtg gaaatccgtc ttagactaac tttcactggt tttctttttc
     2521 ttgatatata agggttcaaa agcgaaaaga ctcagaaaaa gtgcacgaca aatagcccta
     2581 aaacagagtc gtcttagagt aacttccagt tttgggagag agatggaagt tactttgaga
     2641 agttacggta gtcagatttt tttagaaaaa cattttataa atattcacat atctcctata
     2701 tttatggtaa aatagaatta tcagtttatt ttggagtcaa agatgaatat atttagaaca
     2761 aagaatgtta gtttagataa aacagagatg cataggcatt tgaagttatg ggatttgatt
     2821 ttgctgggta tcggagccat ggtagggaca ggcgtcttta caatcacagg tactgcagct
     2881 gcaacacttg ctggcccagc cctagtgatt tcaatcgtta tttctgcctt gtgtgtggga
     2941 ttatcagccc tcttttttgc agaatttgcc tcgcgagtac ccgctacagg aggtgcctat
     3001 agttacctct atgctatctt aggagaattc cctgcctggt tggctggttg gttaaccatg
     3061 atggagttca tgacagccat atcaggcgta gcttcgggtt gggcagctta ttttaaaggc
     3121 ttgctctctc aatacgggat agcctttcct caggctttaa atggtacctt taatcctcaa
     3181 gcagggacat ttgttgattt attgcctatt cttgtcttgg tcttggtgac ttcgcttgtt
     3241 ttactaaatg ccaaggcagc cttacgcttt aattcgattc tagttatttt gaaattttcc
     3301 gctttagctc tctttgtttt agtaggaatt tggaatatta agtttgataa ttggagcaat
     3361 tttgctcctt acggttttgg acaaatctat ggagctagca ctggtattat ggctggtgcg
     3421 tccttgatgt tcttcggttt tttgggattt gaatccatct ctatggctgt agatgaagtc
     3481 aagactcctc aaaaaaatat tcctagaggg attgtcttat cgctttctat cgtaaccatt
     3541 ctctatgcct tggtgaccct tgttttgact ggtgtggttc actatagtca tttaaatgtc
     3601 gatgatgccg ttgcctttgc ccttcgtagt gttgggatta gttgggcagc caactatgtg
     3661 tcattagtgg ctatcttgac cttgattaca gtttgtattt cgatgaccta tgccctatcg
     3721 cgtatgattt acagtttagc acgtgacggc ttagtgcctg ctgcctttaa ggaactgacg
     3781 aagactagca agataccaaa gaatgctact atcttgacag gtctagcttc agcagtagca
     3841 gcaggaatgt tcccactagc cagtattgca gcctttttaa atatttgtac cttagcctac
     3901 ttgatcatgt tggcttatgg tctgattcgc ttacggaaag aaaaaggaat gcccaaagct
     3961 ggggaattta aaacaccatt ggtacctctg ttaccaattt tatcgatcat catttgttta
     4021 tccttcatgt tacagtataa tatgaacacc tggattgctt tcctagttgc gttgttagta
     4081 ggaagtatta tttacttcac ttatggctat aagcattcta ccatagaaga ataaagtgaa
     4141 agtctattga gttgttgaca ctcagtagat ttttatatgt gaaagaaatt tcaaattttt
     4201 tctaaaaata tcttgacaga ttaaattttc aggagtagaa tatttactag ttaattaaat
     4261 ggttaaggag ttgttcatga agaaacaaaa tttattttta gtcctgttaa gtgtctttct
     4321 tttgtgcttg ggggcttgtg gtcaaaagga aagtcagaca ggaaagggga tgaaaattgt
     4381 gaccagtttt tatcctatct acgctatagt taaggaagta tctggtgact tgaatgatgt
     4441 tcggatgatt cagtcaagta gtgggattca ctcctttgaa ccttcggcaa atgatatcgc
     4501 agccatctat gatgcagatg tctttgttta ccattctcat acactcgaat cttgggcagg
     4561 aagtctggat ccaaatctaa aaaaatccaa agtgaaggtc ttagaggctt ctgagggaat
     4621 gaccttggaa cgtgtccctg gactagagga tgtggaagca ggggatggag ttgatgaaaa
     4681 aacgctctat gaccctcaca catggctaga tcctgaaaaa gctggagaag aagcccaaat
     4741 tatcgctgat aaactttcag aggtggatag tgagcataaa gagacttatc aaaaaaatgc
     4801 gcaagccttt atcaaaaaag ctcaggaatt gactaagaaa ttccaaccaa aatttgaaaa
     4861 agcgactcag aaaacatttg taacacaaca tacagccttt tcttatctag cgaagagatt
     4921 tgggcttaat caacttggta ttgcaggtat ctctcctgaa caagaaccaa gtccacgaca
     4981 actaacagaa attcaggaat ttgttaaaac ctataaggtt aaaacgattt ttacagaaag
     5041 taatgcttct tcaaaagtag ctgaaactct tgtcaaatca acaggtgtgg gtcttaaaac
     5101 tctgaatcct ttagaggcag acccacaaaa tgacaagacc tatttagaaa atctggaaga
     5161 aaatatgagt gttctagcag aagaattaaa gtgaggaaag aatgaaaatc aataaaaaat
     5221 atgtagcagg ttcagtggca gttcttgccc taagtgtttg ttcctatgaa cttgggcgtt
     5281 accaagctgg tcaggataag aaagagtcta atcgagttgc ttatatagat ggtgatcagg
     5341 ctggtcaaaa ggcagaaaat ttgacaccag atgaagtcag taagagggag gggatcaacg
     5401 ccgaacaaat tgttatcaag attacggatc aaggttatgt gacctctcat ggagaccatt
     5461 atcattacta taatggcaag gttccttatg atgccatcat cagtgaagag ctcctcatga
     5521 aagatccgaa ttatcagttg aaggattcag acattgtcaa tgaaatcaag ggtggttatg
     5581 tcattaaggt aaacggtaaa tactatgttt accttaagga tgcagctcat gcggataata
     5641 ttcggacaaa agaagagatt aaacgtcaga agcaggaacg cagtcataat cataactcaa
     5701 gagcagataa tgctgttgct gcagccagag cccaaggacg ctacaccaca gatgatggtt
     5761 atatctttaa tgcttctgat atcattgaag atactggtga tgcctatatc gttcctcatg
     5821 gcaatcactt ccactatatt cctaagagtg atttatctgc cagtgaatta gctgctgccc
     5881 aagcctattg gaatgggaag cagggatctc gtccttcttc aagttctagt cataatgcaa
     5941 atccagctca accaagattg tcagagaacc acaatctgac tgtcactcca acttatcatc
     6001 aaaatcaagg ggaaaacatt tcaagccttt tacgtgaatt gtatgctaaa cccttatcag
     6061 aacgccatgt ggaatctgat ggccttattt tcgacccagc gcaaatcaca agtcgaac
//
LOCUS       DAVHSH010000083         6008 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000083 DAVHSH010000000
VERSION     DAVHSH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.084"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            70..1329
                     /locus_tag="VVR08_001978"
     CDS             70..1329
                     /locus_tag="VVR08_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU6075808.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1405..1540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1579..2079
                     /locus_tag="VVR08_001979"
     CDS             1579..2079
                     /locus_tag="VVR08_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU6075809.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNNFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2155..2523
                     /gene="rplL"
                     /locus_tag="VVR08_001980"
     CDS             2155..2523
                     /gene="rplL"
                     /locus_tag="VVR08_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU6075810.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2725..2898
                     /locus_tag="VVR08_001981"
     CDS             2725..2898
                     /locus_tag="VVR08_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075811.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            2895..3674
                     /locus_tag="VVR08_001982"
     CDS             2895..3674
                     /locus_tag="VVR08_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6075812.1"
                     /translation="MKRITANQYHTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVANSNRPSVKKRLGQDENETAPVSHSAPSETEVSETKYSE
                     TDSLFIEDEEERYTQPILKRKVEKVTKYDQDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            3773..5131
                     /gene="dcm"
                     /locus_tag="VVR08_001983"
     CDS             3773..5131
                     /gene="dcm"
                     /locus_tag="VVR08_001983"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU6075813.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLEKRQNGRRFKENQEPMFTLNTQDLHGIVVVGDLPTSFK
                     ETGRVYGSDGLSPTLTTMQGGDKIPKILIPEPIHFLKIREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLINGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     FK"
     gene            5115..5564
                     /locus_tag="VVR08_001984"
     CDS             5115..5564
                     /locus_tag="VVR08_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075814.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQIFLMPNYLCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGADAFIDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSDLLDSLIVSEYQMEPNLWEVSHD"
     gene            5557..5937
                     /locus_tag="VVR08_001985"
     CDS             5557..5937
                     /locus_tag="VVR08_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075815.1"
                     /translation="MIDLYLSKNNHRNQILLDFFQNYGIEVSCHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELSIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
BASE COUNT         1994 a          996 c         1285 g         1733 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttaaaaaag
       61 gagtctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca aaatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt tggtcaagat
      181 aagccagcat ttttagaaca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca cacccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatctggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag cagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggccc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatca cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct
     1381 ttttttgact atgctatact tatatacggt ttaaaaaaac tgcctaagac agtaggggag
     1441 ctcgactcat aaatatccta ccgaggacaa gacgtatcat gtaaaaagaa gcgtattgta
     1501 ctttcgtgtc taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt
     1561 acggaggtga acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac
     1621 gtagtagctg aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg
     1681 acagttgagc aagatacagt tcttcgtcgt gagcttcgtg gaagcgaagt tgagtataaa
     1741 gttattaaaa actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca
     1801 tctgtatttg ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg
     1861 aaaatcttga acaacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc
     1921 gaaggcgctg tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa
     1981 ggacttcttt ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca
     2041 gtcaaagcgg ttgcagaaag caaagaagac gcggcttaat cttaagctac acagcgtagc
     2101 ctagctacga aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca
     2161 ttgaacattg aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac
     2221 cttgtaaaag ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct
     2281 gcagctgatg cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct
     2341 gcaggcgaca aaaaagttgg cgttatcaaa gttgtacgtg aaattactgg tcttggtctt
     2401 aaagaagcta aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact
     2461 gcagaagctg aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa
     2521 taagaggcat ataccaatta gaattcggaa tactatagta tcagcctttt agaatcgtga
     2581 acacatttta gaaactgata aattaattta gtttcctacc aaaaacccta ccaaaaatta
     2641 atttggcagg gtttttcttt ttaacaaatt tatcgtggag aacaattgaa tattgttctc
     2701 ctttttttat tttcaggagg gaaaatgaca aaagaattac aatcatcacg ctatattgtc
     2761 atttcatttt tagtacgtga aatgggaatt gatattgttg aagccatctc tcttatggca
     2821 gaattagaaa aaagtggctt ggttcgattg gaatcaagtg gagatttaat actcaaagaa
     2881 ctaggaggag ctctatgaaa cgaattaccg caaatcaata ccatacttca gaacggtatt
     2941 ataaattacc taaaattctt tttgaggatg aaaaatatat ggatatgaaa ctagaagtaa
     3001 aggtggctta ttctatttta aaagatcgtt tagaattatc tctcagtcgt ggttggatag
     3061 atgaagaagg ggcggtttat ttagtatttt ctaattctaa actgatgaag ttgttaggtt
     3121 gttctaagtc aaaattactg tctatcaaaa aaattcttaa agaatatgac ttaattgatg
     3181 aagttcaaca gtcttcaagt gagaaaggga gacttgctaa taagatttat ttaggggaat
     3241 tgtcttctac cccagtagct aattcaaaca ggcctagtgt taaaaaaaga ctagggcagg
     3301 atgaaaatga aacggccccc gtctcacatt cagcccctag tgagactgaa gttagtgaga
     3361 ctaaatatag tgagactgat tctttattta ttgaggatga ggaggagagg tatactcaac
     3421 ctatcttgaa aagaaaagta gaaaaggtca caaaatatga tcaagattat atttggggat
     3481 tggtacaaga tcaatttaga cgagaaggtt tttctgaaac agccagtgaa attgctatga
     3541 ctgattttga gagaatctat cagtatgctc ttgacaatgt tcgctttgtt agaagagcgg
     3601 aagtacttgc tgaatttgtg tttaatggcc tgtattctgt ttggaataac cgtgttagaa
     3661 aaggaggtgg ttagatgtcg tcaatcgagt ggatattagt tttgctcatt ttcatttcaa
     3721 gtggtgtgac actttggata ttgatagtcg atcagaaagg ggtaatcaag aaatgagatt
     3781 tattgattta ttttcaggta taggtggttt tcgacttgga atggaaagtg taggacacga
     3841 gtgtattgga ttttgtgaga ttgataaatt tgctagagaa tcttataaat ccatttttca
     3901 aacggaagga gaaatcgaat ttcatgacat acgagatgtt tcagatgacg aatttaaaaa
     3961 acttagaggg aaagtcgatg tcatctgtgg gggattccct tgtcaagcat tttcaatcgc
     4021 aggaagacga ttgggatttg aagatactag aggaactttg ttctttgaaa ttgctcgggc
     4081 ggccaaacaa atccaaccac gttttctttt tcttgaaaat gttaaaggct tactcaatca
     4141 cgataaggga cggacgttca ccacaatcct taccacactt gatgagttgg ggtttgatgt
     4201 tgagtggcag gtgcttaaca gtaaggattt tggcgttccc caaaacagag agagggtgtt
     4261 tattatcgga cattctagaa agaaaggtac ccgactccta tttcctttca gacgagaagg
     4321 tcaagcaact aactctgaga ctttaaaaac actaggaaat ttgaatccat caaaaagtgg
     4381 catgagcggt aaagtctatt attcagaggg gttagcgcca acattagttc gtggaaaagg
     4441 agaaggattt aaagttgcga ttccttgtat gacaccagac agattagaaa aaagacaaaa
     4501 tggtagacga tttaaggaaa accaagagcc aatgtttact ttgaatactc aggatctcca
     4561 tggtattgtt gttgttggag atttaccaac tagctttaag gagactggtc gcgtatatgg
     4621 aagtgatggg ttatctccaa cactaactac gatgcaaggt ggagataaaa ttcccaaaat
     4681 actgatccca gaaccaatcc attttctaaa aatcagggaa gcaactaaaa aagggtacgc
     4741 tcaagcagag attggagatt caatcaattt agaaagacca agttctcagt atcggcgtgg
     4801 tagagttgga aaaggtatag cgaatacgtt gacaactagt ggtcaaatgg gagtagtagt
     4861 ggctagctat gaaggagaag ataagcaagt ttaccatgta gccggtgttt taattaatgg
     4921 acaattttac cgtttgagaa tacgacgaat cactcctaaa gagtgttttc gattgcaggg
     4981 gtttcctgat tgggcttttg aagctgctag aaaagtctct agtaatagtc agctctataa
     5041 acaagctggt aatagtgtaa ccgttcctgt gattgctgca atcgcaaaga aattaaaaga
     5101 aatagaggaa aaagatgaaa gctttaaata aagagtcaat actagattgt gacgaattag
     5161 aaacagaatt acatgatgca gaaatcaaac agctggatga acaaatattt ttaatgccca
     5221 attatctatg tgagtttgaa gtgacatttt tagatgatta ccataaaaaa cataactatc
     5281 cactatttta tgaatcctat cttcaaaacg ttatggaatt cctcgaaagt caggatataa
     5341 agaacggagc tgatgccttt atagatgata atcagaatct tgtttttgtt ttatatggac
     5401 aaggctatcg agccgaggga aaagagggaa tacttacaac ccaagtaact gtaaaagcct
     5461 atgatgaaga caagaaatca attaacttct cagatctatt agattcctta atcgtctcag
     5521 aatatcaaat ggaaccgaat ctttgggagg tctcccatga ttgatctcta tctaagtaaa
     5581 aataaccata gaaatcaaat tcttttagat ttctttcaaa actacggaat agaggtatct
     5641 tgtcattcga tttctgaaat gacaaaggac aaattaattg agatgatgag ctattcttca
     5701 gattgttttg agtttttatc tcctaattta ttacgattta agaaccgtga caatctaaga
     5761 ttaacggatt tcatcgaaat gatattaaaa aatcctgaac taagcatcag acttcctctt
     5821 gcagtttcaa ataagagagt ttatccaaat ctgaatttgg aagaggctag agctctattg
     5881 ccaagagata cgaaacaatt gatttacatg gcacaaacac attatttatc taactaaagg
     5941 agaagcaata tggctgaacg attttgggag aacttgtcca ttattttagc tgaaagaaat
     6001 attagctg
//
LOCUS       DAVHSH010000084         5985 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000084 DAVHSH010000000
VERSION     DAVHSH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.085"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..200)
                     /locus_tag="VVR08_001986"
     CDS             complement(<1..200)
                     /locus_tag="VVR08_001986"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075816.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETNEVS
                     SKHCFEVADETDEVSSKHCFEVA"
     gene            complement(264..1274)
                     /gene="ccpA"
                     /locus_tag="VVR08_001987"
     CDS             complement(264..1274)
                     /gene="ccpA"
                     /locus_tag="VVR08_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU6075817.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1699..2298)
                     /locus_tag="VVR08_001988"
     CDS             complement(1699..2298)
                     /locus_tag="VVR08_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075818.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2299..3396)
                     /locus_tag="VVR08_001989"
     CDS             complement(2299..3396)
                     /locus_tag="VVR08_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6075819.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(3396..4133)
                     /locus_tag="VVR08_001990"
     CDS             complement(3396..4133)
                     /locus_tag="VVR08_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6075820.1"
                     /translation="MKRWLALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTGFSMMSTAIFSFPAVLHTDKMNNWQKILRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPVSLFPDWMQAIGKRLPSYQLMELIKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(4135..5019)
                     /locus_tag="VVR08_001991"
     CDS             complement(4135..5019)
                     /locus_tag="VVR08_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075821.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLVQAGCGIQEIEV
                     NNRSLLDTIFEETQKGDN"
     gene            complement(5006..5200)
                     /locus_tag="VVR08_001992"
     CDS             complement(5006..5200)
                     /locus_tag="VVR08_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075822.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(5197..5328)
                     /locus_tag="VVR08_001993"
     CDS             complement(5197..5328)
                     /locus_tag="VVR08_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEU6075823.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKELEE"
BASE COUNT         1896 a         1343 c          976 g         1770 t
ORIGIN      
        1 gcaacctcaa agcagtgctt tgagctgact tcgtcagttt catctgcaac ctcaaagcag
       61 tgctttgagc tgacttcgtt agtttcatct acaacctcaa aaacatgttt tgagctgact
      121 tcgtcagttc tatctacaac ctcaaaacag tgtgttgcgc agcctttaac cagccgccta
      181 gtccgctcta tggtattcat taagtcaaca tctcttgttt aagagcacaa aatcaggaaa
      241 tcttctcgat tccctgattt tttctattta cgttttcgtg ttgagctacg ttctgtcaaa
      301 ccatgaggta agagaacttc acgttcttcc aactcttcct tatgcataat cttggtcaac
      361 atacgcatac taatggcacc aaggtcataa agaggttggg caatcgttgt caagtttgga
      421 cgggtaaagc gtgagatttg tgaatcatca ctagtaataa tttcaaaatc ttctggcaca
      481 gaaacaccct tatcagccaa accgttcaag actcctgctg ctaactcatc acctgtcaca
      541 actgctgcag ttgcatttga tgaaatcaaa cgctctgcta aggcgtaacc atcatcatag
      601 ctatatttag attcaaatac caaaccctca ctataagcga ttcctgcttt tttcaaggtt
      661 tccttgtagc caactaaacg aaccttacca ttgatgtcat ccactagcgg accgctaacg
      721 aaagcaatac gctcattttc tttagcaagg taactcactg catcaattgt tgcttgctta
      781 tagtcaatat tgacacttgg caactggtgc tcaacatcga cagttcctgc gagaacaatc
      841 ggagtacgtg aacgcgaaaa ttctgagcga attttatctg tcaagtgata acccatatag
      901 ataatgccat ctacctgctt tgaaaagagg gtattgacaa cagaaacttc tttctcgtta
      961 tcttcatcgc tattagctag gacaatattg tacttgtaca tttctgcaat atcatcaatc
     1021 cccttagcca aactcgaaaa ataaccattg gtaatatttg gaatcacgac accgacagtg
     1081 gttgtctttt tacttgcaag accacgcgca actgcatttg gacgataatc caaacgatca
     1141 attacctcta gcactttttt acgggtattc tcttttacat ttttattgcc attgaccaca
     1201 cggctgaccg tcgccatgga aacacctgct tcacgagcga catcataaat ggttactgta
     1261 tcatctgcat tcattccttt tcctgtcctt tctatctcac acattctttt acaagtagag
     1321 gtactgattg aagctctata tctacttaca aaagtgaaga tgtgaaaatt tcgttttcat
     1381 atttctactt attccattct atcactaatt gtaaacactt tcaagtgttt tttgaagatt
     1441 gattgaaaaa atttcataga aaacctaggt ttagctcctt gctaccacct tagactaaac
     1501 aaaaaggagg aaactaagcc ctcctaaagt tatagtaaaa tgaaataaga acaggataaa
     1561 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
     1621 agtttcaatc tactataggt attgttccat tcactaccgt caattttagc acatagtctt
     1681 catgaaaata ttatatcatc ataaccaacc agattctttc gcgatattag ctgcctctgt
     1741 tcgattacct gcatctagtt tcgaaagaat attggtgaca tagtttcgga ctgttccgtt
     1801 ggatagataa agtttgtctg caatttcttg gttagagaag ccctgagcaa ttccctttaa
     1861 aactgcgatt tcttgctccg ttaatggatt gggatgcatc atcaccactt ccatcaattc
     1921 aggcgaatac tccttgcgtc cttcgaggac ggtgtgcaag gtttgcatga ggtctgcaat
     1981 gtttctttct tttaatacat aagcatctac tccagccttg accgcacgtt caaaataccc
     2041 aggacgcttg aaggtcgtca ccacaaccac ctttgtttca agcttttctg ctcgtatcca
     2101 ctccaagact tcaagacctg tcttaacagg catttctacg tcaaggatgg cgatatctac
     2161 agactccttt tctaatagtt ggattgcttc ttgcccattc ttggcttgaa agacagactc
     2221 tacatccggt tgaagcatga gcaactggca catggcatct cgcaacatac tttgatcttc
     2281 tgcgactaat actttcatct actttctctc cttataaagt agtcgaacct gcacttcagt
     2341 tggatgtttc tgactgatta cacttacttc tcctgaaaat ggaaaaacac gatttcggac
     2401 tgtatggagc tcatccccgc ttatagaggc aaagccacag ccatcatctc tcactgttag
     2461 aatgagttct ttctctgtcc gttctaattt caagtagact ttagacgctt tagcatgttt
     2521 gatgatattg gtcactaatt caagcaaaat catggaagcc gttgactcca attcctgagt
     2581 taagctagac ttgtccaagt gattctcaac ttgaacctca attccagcaa tttctaacat
     2641 ctttttcaca gtctctagtt cggatgtcaa agttctagac ttaagatttt ccacaatggt
     2701 tcgcacttca ttcatggaat ccttgctgat ctggtgaatt tcttttaatt ccttttccac
     2761 ctgtggataa gcctccatct gaaataactg caaggctaaa tctgtcttga cactcagcat
     2821 agcaaaggta tgtcccagac tatcatgcaa atcctgaccg atacgactac gttcattttc
     2881 agcaagcaat agatttatct gggcattttg cttgacctga gcttctttca aatcctcgac
     2941 aatacgaatc cgaaccaatc caaaagtcat taaatcgaca aaagtaagaa ttacaagtag
     3001 atagaataga aactcaactt cgattctctg aaaaatcaac agttgcccca caacaaggac
     3061 ttgagcaaga agaaaagtcc agacatgtaa agactttaaa ctacgtacgc tgaaatgata
     3121 acttaagaga ttggatagga aaaagaaaaa ccagatataa ttaacagcaa caaaggcagt
     3181 attcccaact acataagtca gcatgaggcc ccaatatagc caagataggc gctggctctt
     3241 agttgttaaa acacccaaat atgccactac aaatagaata tcaatcaata aatgccaggc
     3301 agaaagccac ccagtcacta cagacaggat ggggaaaatc ataaaaatta aactgatcca
     3361 aaacatataa tgtattcttt tcagtctttc aagcattaag cattctcctt atgaccttga
     3421 aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa gtagataaac tgtggctgat
     3481 agattgattc caccctcatt taagaaggtc ttgattaatt ccatcaactg ataacttggt
     3541 aaacgcttcc cgattgcttg catccagtct ggaaataaag agacgggcat ccagagtccg
     3601 cctaaaacag ccaatcctag ataaagaaga ttgcccacaa cagacatcag ctgactagtt
     3661 ggtaacagcg tcaaggttaa gccaagtgct acaaaagcaa tacttcccaa aatcagcaaa
     3721 atcgcagctc caacccattt tactagaggc atgtctacac ctcttacaaa atgtccaact
     3781 gtaaaaacaa ccagaattga gaccaaataa tcaaccagca tacttgttat ctttgataga
     3841 taatattcta ccatatttac tgggctatga cgtaatattt tctgccagtt gttcatcttg
     3901 tcggtatgta agacagctgg gaatgaaaag atagcggtcg acatcatgga aaagccagtc
     3961 atggagatga ggtaatcacg cataaaattc gcgggtccac ctggtgtgtc ctggtacatg
     4021 ccagaaaaga atagatagaa ggctgtcggc atccctactg acaatagata atagatcaat
     4081 tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta gccatcgttt catcttagtt
     4141 atctcccttc tgcgtttctt caaagattgt atccaacaaa ctacgattat taacttcaat
     4201 ttcttgtatg ccacatcctg cttgaactaa cagttcccaa aaagcatctg cttcgcgtgt
     4261 gactacttgt agagcatcct gtttttgtga ccagttttca accaagttag actgctcaat
     4321 gacttccttg tatgccagag gaaggataaa atgcttttca attccctcac tacgcatagc
     4381 tagaggcgtc gtatcacgaa tcaactctcc cttatttaaa accaaaatcc ggtcagccgt
     4441 atgctctacc tcttcaatat aatgagacga atagagaatc gtgactcctt gcgcttttag
     4501 gtcccgaacg atttcccaaa agcgttgacg agttgaagta tccatggcag cagttggttc
     4561 atctaaaaag acaagctttg gtcgcccaat caaggtcaag acaaaagaga agagacgctt
     4621 ttgcccgcct gacaattttt ctgcgaattg ctctttttgt tgctggtcaa actgcaatag
     4681 ttgatcgatt tcctgatcgc tcaaggaatt tggatagata cgttgaaaga aagcaatcaa
     4741 ctctttgacc tttaatttct gaacgatgac attttcttga ggcagataac ctctaatata
     4801 gtctaactga gaactcgtca ctgacaagcc ttggatggat acttgaccgc ttgtgaccag
     4861 tttatctcca agcagacagt ccaagagtgt ggtcttccca gcaccattgg gcccaatcaa
     4921 ggcgacgcat tcaccttcag ctacctcaaa ggaaataccc ttcaaaatag ccttgccctt
     4981 gatgttttta tttaggcttt ctaccttaat catattcatg atattctcct ttcaaccact
     5041 ccattctcat aaggaaaacg acgaaaatca taaatccaaa ccccaaagca ccacgaatga
     5101 attggcgaag caaggtttgg tcaaaccaac ctgtaaacat ttccactaac cataccaaga
     5161 gtgacaggcc gataaagaaa tagatgatcc ctctcttcat tcctcaagct cctttttcac
     5221 atctccgact aatttcaaac cttctctaac aagccaagac atcattccaa agccagcaaa
     5281 gagctcccaa ggaaaatgat agaaactctc atccaatccc gaaaacatga gttaggtcat
     5341 aactcctgct actactaaac tcactgcgat aatcatttta tttctcatct cttcttcctc
     5401 catttcatac tacaattata gtcttttgaa atcagaggag acagaagctt ctgtcactag
     5461 aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa gcaagataca ctatacaata
     5521 aaacacaatt agaaaaatct aaggcaactt cctcaaaaga gatatcaaac ccaattcaca
     5581 ccataatgta aactaatact tatttaaaat caaaaagagt agaaattttt atcagacaaa
     5641 cacatatata gtgtattgaa tctataacag taggccttaa atactaaaat atttctataa
     5701 attaatttaa ctttcctgat agagctgttc atatcttatt tcaattctct aaattatacg
     5761 ttgaacaaaa cccttctatt tctttcttaa agatttataa gagttataaa atctgttaaa
     5821 tttcaatgtg tatacctaaa ctacggtatt tattgaaaag actggagaca aaaagtatac
     5881 gctgccaaaa tgaattactg aaaatcaaaa aagagagaac caaactgatt ccctcttaat
     5941 gtatataata tctagtttta aaaatacaca ctcacatatc tctgt
//
LOCUS       DAVHSH010000085         5242 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000085 DAVHSH010000000
VERSION     DAVHSH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.086"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            43..1032
                     /gene="manX"
                     /locus_tag="VVR08_001994"
     CDS             43..1032
                     /gene="manX"
                     /locus_tag="VVR08_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU6075824.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            1060..1863
                     /locus_tag="VVR08_001995"
     CDS             1060..1863
                     /locus_tag="VVR08_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU6075825.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            1887..2798
                     /locus_tag="VVR08_001996"
     CDS             1887..2798
                     /locus_tag="VVR08_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6075826.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2854..4188)
                     /gene="pepC"
                     /locus_tag="VVR08_001997"
     CDS             complement(2854..4188)
                     /gene="pepC"
                     /locus_tag="VVR08_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU6075827.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(4405..5127)
                     /locus_tag="VVR08_001998"
     CDS             complement(4405..5127)
                     /locus_tag="VVR08_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6075828.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
BASE COUNT         1415 a         1176 c         1073 g         1578 t
ORIGIN      
        1 ttcttaaatg aaaactaaaa caaaaaagga ggaatgacaa taatgagtat cggaatcatt
       61 attgcgagcc acggcgaatt tgctgcgggt attcatcagt caggatctat gatctttggt
      121 gaacaagaaa aggttcaagt tgtgaccttt atgccaaatg aaggtcctga tgatctatac
      181 gctaagttta ataacgctgt tgctgcattt gacgcagaag atgaggttct agttttggct
      241 gacctttgga gtggttctcc atttaaccaa gctagtcgcg tgatgggaga aaatcctgag
      301 cgtaagtttg ccatcatcac aggacttaac ttaccgatgt tgattcaagc ctacacagag
      361 cgcctcatgg acgctgctgc aggtgtagaa aaagtcgctg ctaatatcat taaagaagcc
      421 aaagatggca tcaaagctct tccagaagag ctaaatccag ttgaagaagt tgcaagcgct
      481 gcagctgctc cagttgccca aactgctatc ccagaaggaa ctgttatcgg agacggtaaa
      541 ttgaaaatca atcttgcccg tcttgacaca cgtctacttc acggtcaggt tgcaactgct
      601 tggactccag attcaaaagc aaatcgtatc atcgttgctt cagataacgt ggctaaagac
      661 gaccttcgta aagaattgat taaacaagca gctccaggta atgtcaaggc taacgtggtt
      721 ccaattcaaa aactgattga gatttcaaaa gacccacgtt ttggagaaac acatgccctt
      781 atcttgtttg aaacacctca agatgccctt cgtgccatcg aaggcggcgt gccaatcaag
      841 actcttaacg ttggttctat ggctcactca acaggtaaaa cattggtcaa taccgttttg
      901 tctatggaca aagaagatgt tgctacattt gaaaaaatgc gtgacttggg tgttgaattt
      961 gatgtccgta aagtaccaaa tgattctaaa aaagatttgt ttgacttgat taacaaagcc
     1021 aatgtcaaat aagccattat ttatgaaagg attttaaaca tgtctattat ttctatggtt
     1081 ttagtagtcg ttgtagcctt ctttgcaggt cttgaaggca tcctcgacca gttccaattt
     1141 caccaaccac ttgtagcctg tacccttatt gggcttgtaa caggtcactt ggaagcaggg
     1201 attatcctcg gtggatcgct tcaaatgatt gcccttggtt ggtcaaatat cggtgctgct
     1261 atcgctcctg atgctgcact tgcttctgtc gctgctgcca ttatcatggt tcttggtggt
     1321 gactttacca agactggtat cggtgttgcc caagcggttg ctatccctct tgccgtagct
     1381 ggtctattct taactatgat tgttcgtaca atttcagttg gattggttca cactgctgat
     1441 gctgccgcta aaaaaggtga cttcggcgct gtggagcgtg ctcatttcat tgcgctactt
     1501 ttccaaggac ttcgtatcgc gcttcctgca gctcttctcc ttatggtacc aactgaaact
     1561 gtacaaagta tccttagtgc catgccagac tggctcaaag atggtatggc tatcggtggt
     1621 ggtatggtcg ttgccgttgg ttacgccatg gttatcaaca tgatggcaac tcgtgaagta
     1681 tggccattct tcgctcttgg tttcgttctt gctgctgtgt cagatattac tctaatcgga
     1741 ttcggtgcta tcggtgttgc tatcgctctt atctaccttc acctttctaa aactggtgga
     1801 aatggtggcg gaggagccgc aacttctaac gacccaatcg gcgatatcct agaagactac
     1861 taagataaga aaggactgaa aacatcatga ctgaaaaact tcaattaact aaatcagatc
     1921 gtaaaaaagt ttggtggcgt tcaaccttct tacaagggtc ttggaacttt gaacggatgc
     1981 aaaacttggg ctgggcttat acactcattc cagctatcaa aaaactctat actaaaaaag
     2041 aagatcaaat cgctgctctt gagcgtcacc ttgagttctt caacactcat ccatacgtag
     2101 ctgctccagt catgggggtt actcttgcgc ttgaagaaga acgtgctaac ggtgtggaaa
     2161 tcgatgacgc tgctatccaa ggggttaaaa tcggtatgat gggacctctt gctggtatcg
     2221 gtgacccagt attctggttt acagtacgcc caatccttgg atctctcggt gcttcacttg
     2281 cccttactgg caatatcttg gggccactcc tcttctttgt tgcatggaac ttgattcgta
     2341 tgtcattctt gtggtatgtt caagagattg gatacaaggc tggatcagaa atcactaaag
     2401 atatgtctgg tggtatcctt caagatatca ctaaaggagc ttctatcctt gggatgttca
     2461 ttcttgctgt ccttgttcaa cgctgggtaa atattaaatt tgctttcgat gtttctaaag
     2521 ttcaactaga tgaaaaggct tatatccatt gggataaatt gccagaaggg tctaaaggta
     2581 tccaagaagc attcgcacaa gtaggacaag gattgtctca aactcctgaa aaagttacta
     2641 ctttccaaca aaacttggat atgttgattc ctggattatc aggactactc cttactttac
     2701 tttgcatgta cttacttaag aaaaaagtat ctccaatcac tattatcctt gccctcttcg
     2761 cagtgggtat tgtggcacat gttcttcaca tcatgtaatc aagcaactaa aaaggaacca
     2821 ggttctaaaa tctgattcct tttttctatg cttttattca gccaaggctc ccattggatc
     2881 ccatggtgca agtacgattg gttctgctcc ataggcagct tgttcttctg ctgtcagcaa
     2941 ttccttacga acaacgattt ggtatgtgta ttcgtccatc caagcgtctg aggcaacaaa
     3001 gtaaccatct gtaccgacct tgtctcccca tgagttttca accttccact tggttgattt
     3061 accattttcg tccaagtcaa cacctgtcaa gaccatggcg tgggtcatca agctttcgct
     3121 atagtccaaa cgtccagcct tgtcttgagt aagtttaatg tccatgcttg attcaaagtc
     3181 ataaacatct gtcgcaagga tgccagcctt acggttgctg agctggccga catcagaacc
     3241 aaaccaaaca gtctcacctg cttgcatttg ggcaatcgcc aattctttca agcgctccat
     3301 tggaacgttg atgtagcgaa ctgcacggct accaaccaca ttccccaaca tctcaactgt
     3361 gtaagatttt ccgtaaggtt tatcagcagt tggagcattg ataacagaaa cgtagtcttc
     3421 taaaggaaga ttgacatatt tcttgtaaaa ctcttgtggt gtgattcctt tttcactttt
     3481 atagttgtta tctttatcgc gataagcaaa gtcaaacttg cgtggtggaa gtcctaatga
     3541 catagcaaga aagttaaaga tttcttgcaa gaggtcttct ttcttagctt gaacagtcgc
     3601 ttgatctgca ccagaaacaa gcaaatcacg caagatttga gcatcttgac gaagcaattt
     3661 attaaggatc gcatttagct cacgactgct gctagatgaa acagactcag gataaactga
     3721 cttaggcacg acaccgtatt tttcaaagag ggaaacgacc atatcccatt gaccgccatc
     3781 ttgttgaggt gtttggagta agaagctaac cttgcggcta gtcaattctt ggtctgaagt
     3841 cgcaatgact tgctccaaga accagtttga tttctcatac ttatcccaga agaaagtgtg
     3901 ggcttgtgac aactcaaagt tctccaattt gtattgcgag atgagtttgt ggcggaaggt
     3961 gttgagagcc gcaaacatcc agcaacgacc agacgctttc tggttagtga ccttgtcctt
     4021 ggttaaatcc aatgagaaaa caggtgtgtt gtctacatgg ctttggcgac attccagagc
     4081 tgcaaaaatt ccgttgtggc tggcagcatt ttcaatcgct tggtatttta catttgcttc
     4141 atagttggca aatagtttat cagtaaatga ttcttgaatc gcgttcatag attcctcctt
     4201 ttattctaca gtctattata actcttttca caaaggaagc aactaaaaaa cataaaaggc
     4261 gaggacattg tccctcacct ttttcgaatt tatactcttc gaaaatctct tcaaaccacg
     4321 tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta gtttcctagt ttgctctttg
     4381 attttcattg agtattaaac taaattaaat aatattagcg cggagaattt ctaattcttc
     4441 cttggtcaag cgacgccatt cccctcgttc caggttctca tctaatacta aagttcccat
     4501 agtcaatcgt tgcaagtcca ccacttcctt gccacagtag cccaccatac gcttgatctg
     4561 atgaaacttc ccttctgcaa tggtcacacg gatttggctc tgattctttt ctgcatctgt
     4621 ggaaagaatc tccagtctag cgggctgaca ggtaaagtct ttgagcggaa tgcccttgat
     4681 aaatgtctcc acatcttctt gggtcataat tcccttgacc tgagcctgat aagtcttgtc
     4741 cacatgacgc ttgggcgaaa gaagaacatg agccagctga ccattattgg tcaagagcaa
     4801 aagaccatgc gtgtcaatat ccaagcgtcc tactggaaaa acttccttac tccgcgccaa
     4861 gtcatccaac aagtccagaa cggttctgtg cttgggatcc tcagtcgctg agataactcc
     4921 tttgggcttg ttcatcatgt agtagacaaa ctcttcatac tccaacactt gcccatcaaa
     4981 gcgaatctca tctatttttt catcaatctg caatttagct gatttttctt ttttaccatt
     5041 tacagtcacg cgcccagcct tgagcaagtt tttgacctca gtccgacttc ccaccgcaca
     5101 ggcaactaaa aatttatcta atctcataga actattatat catatcaaaa ggaggctagt
     5161 acaatgacca acctcctttt cgtttcatac tcttcaaaaa tctcttcaaa ccgcgtcaac
     5221 gtcgccttgc cgtatatatg tt
//
LOCUS       DAVHSH010000086         5192 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000086 DAVHSH010000000
VERSION     DAVHSH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5192
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.087"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            83..880
                     /locus_tag="VVR08_001999"
     CDS             83..880
                     /locus_tag="VVR08_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU6075829.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VVR08_002000"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VVR08_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VVR08_002001"
     CDS             2383..3657
                     /locus_tag="VVR08_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU6075830.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTTEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3669..>5192
                     /locus_tag="VVR08_002002"
     CDS             3669..>5192
                     /locus_tag="VVR08_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU6075831.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGEDFE
                     KRRLDFEKGYFKNLLPYSIVNQTVESLASLNAIFITSNYDYEIENHIKRLKNAVVTIN
                     DLNEFTKNKNGKLQFGDVLHIHGTPDCDVKYFVSSSADYSKTYLKNRENFENLVTWFK
                     ETKPTVLFIGAGLEEDEILSLLCKDSKNYALMKSENTGNQRVDEHYRGVVEGFFSSEN
                     HTQIIWYGDEFEKLPLFVKKLVADINEKLGTHDFYNQWNNLLNPSINQEEYNKNLDSI
                     SNDFKYLSSVLDKVIENDNNQLDQLMLNALLRSETLTVIKKNFVLAFWKFIVKNIEKL
                     SDNEWDVIYKIIYEGSQNYFIDDVFFVYNYAIDNKISSFTNNNKLNELREIISKDGYI
                     VNSNFNKDKTLLGYWLVSAFEQQNRDLYIEEDSEVEVNLNYECVNKLMSILNNPEFLS
                     "
BASE COUNT         1698 a          836 c         1068 g         1590 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatgatttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg agcatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaaaaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgaga gtccaagctg
     1741 ccacaatttg agctatactc atgatgtggg tgcagcagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggcgacgagg aggaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcagcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacga cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagacttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtgagga
     3661 aataagttat ggaagatgat cttaattatg aaaatttgat ggatgatgta accgaggcta
     3721 taaaaaagtt taacttagta atttttattg gcgcaggagt ttcaattgct caaggttatc
     3781 ctaattggaa caattatatt gaacatctta ttaagtattg gcaaggacaa gttttatcgg
     3841 taagtggtga aaaaaggctt ggaagagaac atcacgtagt ttttgattta attagcaaat
     3901 ctagtattag taataaacgt aaagtggatc ttgtaaacta tgaattaaaa aaagtttttg
     3961 gtgaagattt tgaaaagcga cgactagatt ttgaaaaagg atattttaaa aatctattac
     4021 catattcaat agttaatcaa acagtagaat ctttagcaag tttgaatgca atatttatta
     4081 cttctaacta cgactatgaa attgaaaatc atattaaacg tttaaagaat gctgtagtta
     4141 ctattaatga tctcaatgaa ttcactaaga acaagaatgg gaaactacaa tttggtgatg
     4201 ttctacatat ccatggaaca ccagattgtg atgtaaagta ttttgtaagt tcatccgcag
     4261 attattcaaa aacctattta aaaaataggg aaaattttga aaatttagta acatggttta
     4321 aagagacaaa acctactgtt ttatttattg gagcaggtct tgaagaagat gaaattttat
     4381 ctttactttg taaagatagt aagaactatg ccttgatgaa gtcagagaac acaggtaatc
     4441 agagagttga tgaacattat agaggtgttg ttgaaggatt ttttagctca gaaaatcata
     4501 ctcagattat ttggtacgga gatgaatttg agaaactacc tctttttgta aaaaaattag
     4561 ttgctgatat taatgaaaaa ttgggcacac atgattttta taatcagtgg aacaatcttt
     4621 tgaatccttc tataaatcaa gaagagtata ataaaaatct agatagtatt tctaatgatt
     4681 ttaagtatct aagctctgtt ttagataagg ttattgaaaa tgataataat caactagatc
     4741 agctaatgtt aaatgctctg cttcggagtg aaactctaac agtaattaaa aaaaattttg
     4801 ttcttgcatt ttggaagttt attgttaaga atattgaaaa gttaagtgat aatgagtggg
     4861 atgtgattta taaaataatt tatgaaggct ctcaaaatta ctttatagat gatgtattct
     4921 ttgtctataa ttatgcgata gataataaaa tttctagttt tacaaataat aataagctta
     4981 atgaactgag agaaattata tccaaagatg gatatatcgt taattctaac tttaataaag
     5041 ataaaactct tttgggttac tggctagtaa gtgcttttga acagcaaaat cgtgatttat
     5101 atatagagga agatagtgaa gtagaagtta acttaaatta cgaatgtgtt aacaaattaa
     5161 tgtccatact aaataatcca gaatttttaa gt
//
LOCUS       DAVHSH010000087         4833 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000087 DAVHSH010000000
VERSION     DAVHSH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.088"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            54..236
                     /locus_tag="VVR08_002003"
     CDS             54..236
                     /locus_tag="VVR08_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6075832.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            536..1375
                     /locus_tag="VVR08_002004"
     CDS             536..1375
                     /locus_tag="VVR08_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6075833.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1393..3231
                     /locus_tag="VVR08_002005"
     CDS             1393..3231
                     /locus_tag="VVR08_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6075834.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVNQGYKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3244..4659
                     /locus_tag="VVR08_002006"
     CDS             3244..4659
                     /locus_tag="VVR08_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6075835.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     EEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT         1646 a          631 c          937 g         1619 t
ORIGIN      
        1 aacaccccaa aagttagatt ttttctgtct aacttttggg gtgtagttca cagttgaaga
       61 gccagaaaat taaagtgtct tttactcaat caaaaatagt aacgcctatt cttttggtga
      121 ataagactat tgtttggtat ggtgcaatgc cattattagg gaaggtagat gagatgacca
      181 tattacgttt ggaatcagct agtatagttt ctgaactagt ggcaggttta cgatagagaa
      241 aatttttaaa aatttctatg tatgattttc atttctttag tgagactgtt gccattatca
      301 cattcgaatc acacaaaata aaaaaatttc tacaagtact tgacaaatag attgaaatat
      361 cttaaaatga aaatggttac agagttatta attatttaag cttcatgtca ccattaaaaa
      421 ttgaaataaa aggatgttat cactaataca agtgagcagg aacctattta atcacatcgg
      481 aagaagtttc ttgatgtttt taagtaggtt ccttttattt taaaagggaa attttatgat
      541 cataaaacga atactaaacc acaatgccgt aattgcgcaa agtaaaaaag atatcgatat
      601 tcttcttttt ggaaggggaa tagcttttgg aagaaaaact ggagataaag taaatccaat
      661 tgatattgag aaaagttttt ttctcaaaaa tagagataat atgacccgtt ttacagagat
      721 gtttattaac gttcctttgg agttggtgta catcaccgaa aaaataatta atctaggtaa
      781 aataacatta ggtaataatt ttgatgaaat tatctatatt aatttaacgg atcatatttc
      841 ttcgagcata gaacgttata aagaaggagt tattatttcg aatcccctac gctgggaaat
      901 ctcgaaatat tataaagaag aatttgaact tgggaaaagg gctttacaaa taataaaaaa
      961 agagttaggt attgaacttc caattgacga agctgcattc atagcgctac attttgttaa
     1021 tgctaattta gaaaataatt ttcaagagtc gtataaaatc actgaaataa ttatgggaat
     1081 tgagaaaatc attcaagatt tctattgtac tgagtttaac caagattcta ttgattatta
     1141 tagattcata actcatataa aattatttgc ccatcgcttg gttgaaaata caacttattg
     1201 tgacgatgat gatgaagact tgttagcatt aatgaaaaat aaatatccta gagaatatga
     1261 atgtggtgaa caggtggcaa tgtttataca aactgagtac aattatttgc tgacttctag
     1321 tgaattagtt tatttgatgg ctcatattcg tcgcttaaca aaaaatttag attaatagaa
     1381 taggagaata ccatgagtta taaagatacg gtacaaaaaa tcctcgatgt aattggaggt
     1441 gaaaaaaatg tcaatagagt tacccattgt gtaacacgtt taagattaga attaaaagat
     1501 gaaaatttag tcaatgatga tgatgtgaag aagataccag gtgtaatagg tattatgaaa
     1561 aaaaatggac aatatcaaat tatacttggt aatgatgtag ctaattatta taaagaattc
     1621 gttaaacttg gcaattttga atccgattca gttaatcaag ggtacaaagg gaatatttta
     1681 gaaagaatca ttgagtatat cgctggttcc atgactccaa tcattccagc aatgttaggg
     1741 ggaggtatgc tgaaagtctt ggtaattatt ttaccaatgc ttggtatatt gcaatcagat
     1801 tctcagacta ttgctttttt gacatttttt ggggatgctc catattattt cttaccgctg
     1861 ttattagctt attctgcatc acaaaaatta aaagtaacat ctacattagc tatgtctgta
     1921 gcaggtgtac ttctccatcc aaattttgtt caaatggtgc aatcagggaa tcctcttagt
     1981 ttatttggtg cacctgtgac accagctagt tatggttcat cagtcgttcc aattcttatt
     2041 atggtttggt tgatgaaata tattgaaaaa ataattgcta aattaacacc agctattact
     2101 aagagttttt tgcaacctac gctagtatta ttagtatcaa gctgtattgc cttagttgta
     2161 gtcggaccta ttggagtaat tgttggtgaa ggattatcaa atctagttgg gcaaatgtat
     2221 ggtgtagctg gatggcttac attagctatt cttggtgcta ttatgccatt tattgttatg
     2281 actggaatgc attgggcttt tgcacctatt tttttggcgg catctattgc tactccagac
     2341 gtattaattc ttccagcaat gttagggtca aacttagctc aaggggctgc ttcgatggct
     2401 gttgcattaa agagtaaaaa taataataca aaacaaattg cttttgcagc aggtttctca
     2461 gccttacttg cagggattac cgaacctgca ttatatggtg tgactttaaa atataaaaaa
     2521 ccgctttatg cagctatgat tggtggtgga ttagcgggat tatttgcagg tcttactagt
     2581 gttaaagcat atctatttgc tgtcccatct ttgatagcgt tgcctcaatt tatttattct
     2641 gatgtgccat caaatattgt aaatgcttta attgtggcgg tcatttcggt tgttattacc
     2701 tttgtattag cttatatatt tggaatcgat gaagaagaga gttctagcaa tttagaagtt
     2761 gaagctggag tttcaaataa aaaaatgata ttttctccta tatcaggaga aatcattccg
     2821 ttaagcgatg tccaggataa aacattttca gataaactaa ttggagacgg agtagcgatt
     2881 atcccaagtg aaggtaaggt ttatgcacca tttgatggga aaattacaaa tatttttccg
     2941 actaagcacg caattggatt gaagagtgat gagggtgttg agttactaat tcatattgga
     3001 ttagatactg ttgagctaaa aggtcaaggt tttattagtc atgtagaaga aggagacaga
     3061 gttttcaaaa atcagttgat ttttgaaatg gacttgaatt taatcaagac taaaggctac
     3121 gaaacagtta caccagtaat tgtaacgaat accaatgatt ttctagatgt attagtatta
     3181 cctaataatc agacaatcga gcattctaag gaattactgg taatattata atggaggaaa
     3241 gttatgacca tttttccaga tgattttctt tggggtggag cggttgcagc taatcaagta
     3301 gagggagcat ataatgaaga tggtaaggga ttatcagttc aggatgtgtt acccaaaggt
     3361 ggattaggag aagcaacaga aaatcctaca gaagataact taaaattgtt aggtattgat
     3421 ttttatcata aatataagga agatatatcc ttgttttctg aaatgggctt taatgttttt
     3481 cgtacttcta ttgcatggag tagaattttt ccaaaaggag atgaagaaga acctaacgaa
     3541 gctgggttga aatattatga tgaattattt gatgaactac atgctcacgg gatagaacca
     3601 cttgtaactc tttcacacta tgagactcca ttatatttag caagaaaata tcatggatgg
     3661 attgatagga gaatgattca tttttatgaa aaatttgctc gaacagtttt agaaaggtat
     3721 aaagataaag ttaaatattg gcttacattt aacgaagtaa actctgtttt ggaattaccg
     3781 tttactagtg gaggaataga tatacctaag gagaatcttt cgaaacaaga attatatcaa
     3841 gctatacatc atgaattagt cgcctcgagt ttggttacaa aaattgctcg tgagattaat
     3901 tcagagttta aggtggggtg tatggtatta gctatgccag cttatccaat gactccaaat
     3961 ccaaaagatg tatgggcgac tcatgagtat gagaatctaa attatctatt ttcagatgtg
     4021 catgttagag gttattatcc gaattatgca aaaagatatt ttaaggaaca tgacattaac
     4081 atagagtttg cagctgaaga tgcagagtta ttaaaaaatt atactgtaga ttttttatcc
     4141 tttagctatt acatgagtgt gactcaatct gctcttccaa cacagtataa ttcaggagaa
     4201 gggaatatta ttggtggctt agtaaatcct tatttagagt cttctgagtg gggatggcaa
     4261 attgatccaa ttggactacg tataatttta aatagatatt atgaccgtta tcaaattcca
     4321 ttatttatag tggaaaacgg attaggtgct aaagatcaac taataaaaga tgaatttaat
     4381 aacttaacag tccaagatga ttatagaatt cagtatatgg aagaacattt attgcaagta
     4441 gctgaagctc tacaagatgg tgtggaaatt atgggctata catcttgggg atgtattgac
     4501 tgcgtttcta tgtccactgc acaactttct aaaaggtacg gtctcattta tgttgatcga
     4561 aatgatgatg gaaatggcac attcaatcga tataagaaaa tgtcctttac ttggtataaa
     4621 ggagtgattg aatcaaatgg agaatcctta ttcaaatagt ttgtttattg atgattagat
     4681 attatcacgg ttaaggcaac atctcattaa atatgaaata aagaggtttg gaagacatca
     4741 aattctaaac ctctttattt tataggggga ttaattaatt taattttgtt acagagagcc
     4801 gattataaat agttaactta ggatagatgg gtt
//
LOCUS       DAVHSH010000088         4819 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000088 DAVHSH010000000
VERSION     DAVHSH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4819
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.089"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..435
                     /locus_tag="VVR08_002007"
     CDS             <1..435
                     /locus_tag="VVR08_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6075836.1"
                     /translation="SNTLIYLKALNTLSNFYSLVGREQEYEANYSHLMELYQTKNFEH
                     QEFLFGYIRVRYNYSHYLVSKEKYNEAIQEALETIELCKQRQTSYQLAPLLILVGNAG
                     AKFLDKEQVKNYYIEARELCKIYNNPLMLMKIENYLKELDTV"
     gene            complement(540..788)
                     /locus_tag="VVR08_002008"
     CDS             complement(540..788)
                     /locus_tag="VVR08_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEU6075837.1"
                     /translation="MVLSYRLLLFIIFLFNLFAKMNLTSTIKLEQVEKEIEENQRFMT
                     KWIDDYEYKVRRLENFINILDNTRNQNVTKLERETKSV"
     gene            complement(992..2815)
                     /locus_tag="VVR08_002009"
     CDS             complement(992..2815)
                     /locus_tag="VVR08_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU6075838.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPDKTKNLTLVSDYDMRNFLD
                     FPSYEEMVQMYHENFINNDTLYNFRHDRLEEKQRQIHAHHIIQSFSPEDNLTPEQINQ
                     IGYETMKELTSGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQQYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFSHKHATFFMTDSSMKQVVRGNKLNRKQPYTEEFFKNYFAKREMEELMEFLLSK
                     AENIDDLIETAKLFDLTIIPKQKHVYFQLAGVEVKETELDQKNLYGVEFFQDYFESRK
                     DWQNPEIEDLVQFYQEEKFSKEKELPRDEKFWEFYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYIKVKFGIRQEGLIFVPNMQLDIEEEKVKVFIRETSSYYVYHKDDPEKNRY
                     MKGRTLIRQFSSENQTIPFRRKTTVDMIKEKIEEVYTLLELDMDKHSYITIKDDLIHE
                     LAASELRINALQERVTTLNQVAEYLLASVENKQKMKLNLSKLNITDKIGIDVVEKELN
                     ELGIQIELESNRYENIVFKVNKFINRLSKKISKEEGICFQK"
     gene            complement(2802..3167)
                     /locus_tag="VVR08_002010"
     CDS             complement(2802..3167)
                     /locus_tag="VVR08_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU6075839.1"
                     /translation="MEHRYRINLKKVFLSDIELNQLNRNIDQSSCQSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISSEELQELKKGIAELIKE
                     VEKEFTIQAQKLREFHGHH"
     gene            complement(3172..3528)
                     /locus_tag="VVR08_002011"
     CDS             complement(3172..3528)
                     /locus_tag="VVR08_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075840.1"
                     /translation="MKRDVRDIRKQFRLTDEEEKQILALMREQGDTNFSDFLRKSLLS
                     SDLQKQIEIWFTLWQSQKLEQISRDVHEILISIQSERQVTQEHVSILLTCVQELIKEV
                     GNSIPLSQDFQDKYMR"
     gene            3890..>4819
                     /locus_tag="VVR08_002012"
     CDS             3890..>4819
                     /locus_tag="VVR08_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6075841.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIRISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALQKGLIYARNGSINTPKDSSAPFELINKL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFVENEDGRFFIYNPNPDFYIKLTDDDANRFKT
                     MPYSLNQYQTNVDWQLVQLRYRHLTIIDFMALYLDQGNCLVPSPDLEDFECGYSDTIY
                     YHCLYKNTLKYQLLKVFSSISGLEKYPLDRFKNN"
BASE COUNT         1542 a          869 c          732 g         1676 t
ORIGIN      
        1 tcaaatactc tgatttattt aaaggcattg aatactctat ctaatttcta ttccttagtg
       61 ggtcgtgaac aagaatatga ggcaaactac tctcatttaa tggagttata tcagacaaaa
      121 aattttgagc atcaagagtt tttatttggc tacatcagag ttcgttacaa ctactctcac
      181 tacctagtgt caaaggaaaa atataacgaa gctatccaag aagctcttga gacgattgaa
      241 ctctgtaaac aaagacagac aagctaccaa ctggctcccc tacttattct tgtaggaaat
      301 gctggagcca aatttctaga caaagaacaa gtcaaaaatt attatataga agcaagagag
      361 ttatgtaaga tttataacaa tcctttaatg ttgatgaaga tagaaaatta tttgaaggaa
      421 ttagatactg tatagttaat cttgacatta tagtttttct gaaacgttaa ataacctgta
      481 aggctgatag tgatattaat actatcagcc ttataatttt tccatggtat ctccaataac
      541 tatactgatt ttgtttcccg ttctaatttg gtaacatttt gatttcttgt attatcaagt
      601 atattgataa aattctctaa tctcctaacc ttatattcgt aatcatctat ccatttagtc
      661 ataaatcttt gattttcttc gatttctttc tccacctgct ccagtttgat agttgaagtc
      721 aggttcatct tggcaaagag attgaaaaga aaaatgataa ataagagtaa acgataagat
      781 aaaaccattg agcagttgaa tttatccaac aaatcaataa aaaaactagt aaggaaataa
      841 gtgaataaat ataaggagat atttgctcaa aatgatgatt tttttgtatc gtatgtgata
      901 actaaatcta cgactgatgc aataaaaaat atcataattc caaatatgtt ttataaaaga
      961 tacacatttt atataatggt tgtctgggtt cctatttttg aaaacatatc ccttcttctt
     1021 ttgaaatttt cttactcaaa cgattgataa acttattcac tttaaatacg atattctcat
     1081 atctattgct ctctaattct atctggatac ctaactcatt caattccttc tcaacaacat
     1141 caatgccaat tttatcagtt atattcaatt ttgaaagatt caatttcatt ttttgcttat
     1201 tttcaactga agccagtaaa tattctgcta cttgatttaa ggttgtcact cgttcttgca
     1261 aagcattgat tctcaattct gaagctgcca attcatgaat taaatcatct ttaattgtaa
     1321 tataagagtg cttatccata tccagctcaa gtaaagtata cacttcctca atcttctctt
     1381 taatcatatc gactgtcgtt tttctgcgga atggaatcgt ttgattttca gagctgaact
     1441 gtctaatcaa ggttcgacct ttcatgtagc gattcttctc aggatcgtct ttatgataga
     1501 catagtagga gctagtttct ctaataaaaa ctttcacctt ctcctcttca atatcgagct
     1561 gcatattcgg cacaaagata agcccctcct gacgaatacc aaacttgacc ttgatgtaaa
     1621 taccatcatc tactactttt tcaatttgat tgagtgacaa ctctacctca aactcatgaa
     1681 cggcatctct gttgctcttg aactcttgat agaattccca gaacttctca tctcttggga
     1741 gttctttttc tttggaaaat ttttcttctt gataaaattg aaccaaatcc tcaatttctg
     1801 gattttgcca atcttttcta ctctcaaaat aatcttggaa aaattctaca ccataaagat
     1861 ttttctggtc tagttctgtc tctttcacct ccactcctgc caactggaaa tacacatgct
     1921 tttgtttggg aatgatagtt agatcaaaaa gtttcgcagt ttcaatcaag tcatctatat
     1981 tctcagcctt tgataagaga aattccatga gttcttccat ttcccttttg gcaaagtaat
     2041 tcttaaaaaa ttcttctgta taaggttgct tgcgattgag tttattgcca cgcaccacct
     2101 gtttcatgga tgagtccgtc ataaaaaagg tcgcatgctt gtggctaaaa tccatttcta
     2161 catgtagtag tggagcattc tttttgaaat cctcaaagtc tctagaatgt tccatcaaaa
     2221 aatagagtcg ctgcttgagt tcatacttgt gattggtctt gcgataaact tcatactgct
     2281 ggtgagaata gcgattctct ataattttcg cccctgcaat tttagaaaat ctatctgaaa
     2341 tcattcgaag atttcgctcc actttataat cccacttaag ttttttgtca gaattgctgt
     2401 caaccgagtt tataatgatg tgattatgca gatggtcttt atcaacgtgg gtcgcaacga
     2461 taaagcgaaa ctttccacta gtcaattctt tcatggtctc ataaccaatc tgattgattt
     2521 gttcaggagt gagattgtcc tctggcgaaa aggactgaat aatatggtga gcatggattt
     2581 gtcgttgttt ctcctccagc ctatcgtgtc gaaaattgta aagcgtgtca ttgttgataa
     2641 aattttcatg atacatctgc accatttcct catagctagg aaagtccaga aaattcctca
     2701 tatcataatc cgacactaag gtaagatttt ttgttttatc aggattgaga atatacttga
     2761 tgagctttct gcgataactc tttccatgaa tggcaaaatg cttagtgatg accatggaac
     2821 tccctcagct tttgagcttg tattgtaaat tctttctcaa cttcttttat caattcagcg
     2881 attccctttt tcaactcttg caattcttcg ctagaaatca actgagattg gttcacactt
     2941 cgagcaatct gattgatgtt attgccaatc ctcttcaact caaacactaa gtcttggtag
     3001 ccatttgtat caatggtgat gaaattcatt ccagggtcaa gtagggtgcg tctcgcatat
     3061 tcagaaaaag attggcagct actttggtcg atatttctat ttagttggtt caactcaata
     3121 tcagacaaaa acactttctt gagattgatt cggtaacgat gttccatgtg tctacctcat
     3181 atatttgtct tggaagtctt gactgagagg aatggagttg ccaacttctt taatcaattc
     3241 ctgtacgcag gttaagagaa tagatacatg ttcctgggtg acttgacgtt ctgactggat
     3301 cgaaattaaa atctcatgaa catcacggct gatttgttct agtttttgag attgccaaag
     3361 ggtgaaccat atctctatct gtttttgtaa atcagaggag agtaaacttt tacggagaaa
     3421 atctgaaaaa ttagtatctc cctgctctct catcaaagct aaaatttgct tttcctcttc
     3481 atctgttagg cgaaattgtt ttcgaatatc acgcacgtct cgtttcatac tactacttcc
     3541 tttccaaaat acctgtactg acaatgtctg ctaccgtaca atgtcagtac acttttacac
     3601 caactgattt tcattcttgt aaggctttgc gagctcagat attgtgtcca caatatccca
     3661 aaaatcatat cgccagctga ctaaaacctt ccagttttga cagctaacga taagataact
     3721 tggtggctcc gcccccaaac ccccatagaa aatcaaaaat tgattttcta tgaatgatat
     3781 taggataaca gggaagattt ggaaaagata tcacagctaa tatagttatg attgactttc
     3841 tctgattcta tgataaaatt tctgtaaact aatatttgga gaaataaaaa tgctgagtct
     3901 agatcaaata catttactat tgaatactcc tgaagatgag tttcatgatt ttaaacaaaa
     3961 atggcatcat tctaaaactg aattggtgcg tgatatctta aattttgtca atacatcaca
     4021 tcatgaagat tgttatatca tctttggaat tgataatatc actttagata taatcggtgt
     4081 aaacaatgat gataatagaa gaaatgaaga agatctaaca gatttactac ataaactctt
     4141 tatatcaaca aataatcaaa ttagaattag catacaaact gaaactatag acaacaaaga
     4201 aattgacatc ttaattattc atgatacaga taaagttcct gtatttttaa caaaagatta
     4261 taagcctaag aaagatactg cattacaaaa aggattaata tatgctagaa atggctctat
     4321 aaatactcct aaagactcct ctgctccatt tgagttaata aataagttgt ttcaaaagtt
     4381 taatcatacc gacttaaata tcaaagagca gtattttcat gttttaaaag actataaaaa
     4441 ttggttcttc gttgaaaatg aagacggaag attttttatt tataatccta atcccgattt
     4501 ttatattaaa cttaccgacg atgatgcaaa tcgtttcaaa actatgcctt atagtttaaa
     4561 tcaataccaa accaatgttg attggcaatt agtacaactt cgttatcgac accttacaat
     4621 tatcgacttt atggctttat atttagatca gggaaattgt ctagtgccct cccctgattt
     4681 agaagatttt gaatgtggtt attctgacac tatttattac cactgtttat acaaaaatac
     4741 tttaaaatac caattgctga aagttttctc ttcaatatct ggtctcgaaa aatatccttt
     4801 agatagattt aaaaataat
//
LOCUS       DAVHSH010000089         4597 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000089 DAVHSH010000000
VERSION     DAVHSH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.090"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(156..2138)
                     /locus_tag="VVR08_002013"
     CDS             complement(156..2138)
                     /locus_tag="VVR08_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6075842.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(2337..2495)
                     /locus_tag="VVR08_002014"
     CDS             complement(2337..2495)
                     /locus_tag="VVR08_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU6075843.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(2566..2712)
                     /locus_tag="VVR08_002015"
     CDS             complement(2566..2712)
                     /locus_tag="VVR08_002015"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075844.1"
                     /translation="MEYSLKYKETFKTILKDGHLVLSNNLAECAIKSLVMGRSKRVQW
                     TLLA"
     gene            complement(2758..3015)
                     /locus_tag="VVR08_002016"
     CDS             complement(2758..3015)
                     /locus_tag="VVR08_002016"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075845.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEATPKQADKSSLGA
                     KGLAYCNQLFSLERDWEALPADERLQKRQEELQPLMEDFFA"
     gene            complement(3088..3315)
                     /locus_tag="VVR08_002017"
     CDS             complement(3088..3315)
                     /locus_tag="VVR08_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075846.1"
                     /translation="MRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKAENQAIT
                     LYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            3343..3651
                     /locus_tag="VVR08_002018"
                     /pseudo
     CDS             3343..3651
                     /locus_tag="VVR08_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3674..4024)
                     /gene="tnpB"
                     /locus_tag="VVR08_002019"
                     /pseudo
     CDS             complement(3674..4024)
                     /gene="tnpB"
                     /locus_tag="VVR08_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(4005..4190)
                     /locus_tag="VVR08_002020"
     CDS             complement(4005..4190)
                     /locus_tag="VVR08_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075847.1"
                     /translation="MPQPIVPVDIPQSRPFDSKKRNDILLKIRIGKLELSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(4474..>4597)
                     /locus_tag="VVR08_002021"
     CDS             complement(4474..>4597)
                     /locus_tag="VVR08_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002203452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6075848.1"
                     /translation="ADKDKQDKLPNTGETTGTYLSILGMITAVFASLLYRSKKK"
BASE COUNT         1357 a          950 c          819 g         1471 t
ORIGIN      
        1 aggaaacaag taaaattaac aaaaattttc tctattctga caaaaagagg ctccaacttt
       61 tgggggtcag tacatttaga atctttcttt acaaatgtaa aaaaggattc agcattcaag
      121 agaaatacta aatcctttct tatattttgc aacagttatt tcacatgttt tgcgagatct
      181 tcttgagcct ttttattaga ctcttctttt tctttcatcc atttttcctg agctttttgg
      241 tattcatcta cagtgactgc cttgtcttga agttccaagt atttatataa gattggttca
      301 cttgtacctt tatttcctga caatgcaaat ggtattgtaa atggtaccat cttagacaag
      361 attggacgcc ctgtacgaga tgtagttgga ataatcaaag cactatctgt caaccaagct
      421 tgggctgcag cgtatttatc atagcgttta gcaacatctg tagcctcatc accagcctca
      481 gtaaccaatt tttcgtagtc atatagacct acttttttag cagctacatt atcttcccct
      541 gagtcaaacc ctaaatatgt tttagtactt tctcctacag aaggtttgat aatatcaagg
      601 taggttgatg gatcggcaaa gtctggaccc caaccgacat tatctgataa atcccagtct
      661 tcgccagcag cattttcagc aaaatatgta atattgttta cttcgtcttt ttgtagttgt
      721 tgaatatcaa taatgacatt atcagctcct aaagttgctt ccaaggattg tttcatagat
      781 tggacgcgct gaacttttgt agttgctgtt tggtcaactg gcatatccaa atgaattggg
      841 aatgtcacac cttctgcttg taaggctgat ttagctttag caaattcagc cttggctttt
      901 tctggattgt aaagaccatc ctgagaatct gcaagattaa catccttcca ttcatcccca
      961 taagtgacca atttctcttt gaccatatcg ccaaagtttt taccatctgc ttgaacaaat
     1021 gttggtggca caaagagatt acgcaagatt ttacttgctc cagtttgtcc attcaactga
     1081 gaggcatagg ctgtacggtc aaatccaaat gcaatagcct gacggaaatc cttgtttaag
     1141 agagcctttt tagtcgatgc cttttgttcg tcgctggtct tagatgtgta tttataggac
     1201 tgacggtcaa tatttgtacc aactagatac gtaatagagt cttgttgagt atagacaata
     1261 ttgtccttca tactcttctc aagctctgcg aaacttgcac ttgttggata gagacgagct
     1321 gctgtaaggc taccatcttt aaagttttct gcaggtttgc tggtatcttg accatcccag
     1381 aatgacaatt taactttgtc aatatgcaca ttgtccttat cccagtagtt cggatttttc
     1441 gcaaattcaa cagaggattt ggtcacaatg gatttcaaca aataaggacc gttatacaag
     1501 agactacttg gatccgtagc tttggcaaaa tcatctcctt ttgaattcaa aaactcttca
     1561 ttaactggcg caagcacacc catggttgtc ttagaattcc agaagctttc tggtttgttc
     1621 aaagtgtact gaactgtctg ttcatccaga gccttaattc ctacttgtga gaaatctttg
     1681 atttcccctt ttacataggc atccaaccct ttgattgatt cttgaacaag gtaaagagca
     1741 tctgattttt tatcagcagc atattttagt cctgttacaa agtcttgagc tttgactgcc
     1801 gcgtattctt caccttcaga agtataccat tttgcatcct tacggatagt ataagtgtaa
     1861 gtcaatccat ccttggatac agaccaatcc tcagccatag acggcacaaa gttcccgtag
     1921 cgatcatttt ctagcaaacc atcaaccacg ttactggtaa tatttgctgt cgcagcctta
     1981 gcagttgtca aatagttgag gttatcaggg tctgtctcat aaatgtatga gaatgtcttc
     2041 tcacctttag tgcttgaacc tgatccagag catgcagcta aagtagtcgc cgccaataat
     2101 gtcacgcccg caagggcaag tagttttgaa cttttcatca ttttctcctt taaaactttc
     2161 tctccattat agactctttt cagaaagttg tcaacagaat tttcagaatt tttgaaaatt
     2221 atttttcaaa caacatcttt gcaaaaaata tgaatatcgt aaccgtccaa taacgaagta
     2281 tattgaaaaa tctccagact agagaactca cggatagttc ctaatctgga gatttcttat
     2341 ttacactttt cttgtacaac tttagtccac ggtaaatagg cctctaaaac ctctttgttt
     2401 acgagagttt cctcgtttgg aagacattct agaagatagg atagatattt ctcgctattt
     2461 aattgatgac gtttagctgt ttccaacaaa ctcataataa tagctcttgc tttagctcct
     2521 tcaaaatttt gagaaaataa ccaccctcgc ttttttaaac tgagcttagg ctaaaagagt
     2581 ccactggact cttttactcc gtcccataac caatgattta atggcgcatt cagctagatt
     2641 attggaaagg accagatgtc cgtctttcaa aatagtctta aaggtttctt tatacttgag
     2701 gctgtattca attgcccttc ctagttttga acccgataaa actgactgac gccggcatca
     2761 agcaaagaag tcttccatta ggggttggag ctcttcttga cgtttctgta gtcgttcatc
     2821 agctggcaaa gcctcccagt ctctttccaa ggaaaataac tgattacaat aagctaaacc
     2881 tttagctcct aacgatgatt tatccgcttg cttgggggtc gcttcaaaaa acttccttct
     2941 cacatgcgcc caacatccaa caagttcagc ttcttccagt tgacgataag cttctagcgg
     3001 ttcgcagttt accaagctta gcgtcgcctt gctcctaaac cttggactgc tatcgcatag
     3061 gcagaactag aggactaaag tcctaagtta ctgccgcaac atatcacaat gcacatagcc
     3121 agaataatct cctaggaatt cttgtactac taaaccactc cgacgctgat catggtggta
     3181 cagcgtgatt gcttgattct cagctttccc agacaaaaag gtccaatagt aagtcagctg
     3241 actatcactc tctagcaccc tataagaagt ttcatccgca tgaagtaagg gctgagtcaa
     3301 tagtctctct cgcaagaggt tataaagggg ctttaggaat aggagctttc acaagcttat
     3361 ccagatgatt atcttttact cgttatggac aatgctatat ggcataaatc aagtatctta
     3421 aagattccga ctaatattgg ttttaccttt attcctccat acacaccaga gatgaacccc
     3481 attgaacaag tgtggaaaga gattcgtaaa cgtggattta agaataaaac ctttcgaact
     3541 ttggaagatg tcatgaatca acttcaagat gttatacaag gactggagaa ggaggtgata
     3601 aagtccatcg ttaatcggag atggactaga atgctttttg aaagcagatg agtataaaaa
     3661 gaaagtcctc atttcaatag aaatcacgac tttctgataa atttattttg ggagtgatag
     3721 aaaagccctt cataagccag tctacttgtt caggtgtgag agctttgaca tccttttctg
     3781 tactgggcca agtcagtctg ccgttctcaa agcgtttata tagtagccaa aatccttgac
     3841 catcccagta aagggcttta aagcggtctt tacgtccacc acaaaagaga aaaacttgac
     3901 ctgaaaaggg aactaattca aagtgggttt taaccagata agccagtgaa tcaatgcctt
     3961 gcctcatatc agttttccca cacacgagat agacctaccc taggctagat agatgaattg
     4021 tcatagagca acaccttatc caaaagctgt tctatcattt cgagattgag agattgaaaa
     4081 aaacttagtt caagcttgcc aatacgaatt ttaagcagaa tatcatttct ctttttagaa
     4141 tcaaaaggac gagattgtgg aatatctaca ggaacaatag gttgtggcat taaaatatcc
     4201 tccaatagtt ttactttact aatagtatac aggaggagct ccatgaatga tagatacctt
     4261 gttatgacgc gcttactata aaaacggaga ggacatcgat cgtcctctcc agatgttagc
     4321 ttttagtcaa tccactacag ttgacaaaga gccaatttta ttcgcttttt atatttaagg
     4381 ttagactttt gtccctcttt gtcgttaaca aaaatacaaa aatcgtcctc aaaaacttta
     4441 atgtagctca taaattggag agaatagcaa aaactatttt ttcttactac ggtacaatag
     4501 gcttgcaaaa actgcagtaa tcataccaag tattgacaaa taagttcctg ttgtttctcc
     4561 tgtatttggc aacttatctt gcttatcttt atcagca
//
LOCUS       DAVHSH010000090         4390 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000090 DAVHSH010000000
VERSION     DAVHSH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4390
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.091"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            31..1056
                     /locus_tag="VVR08_002022"
     CDS             31..1056
                     /locus_tag="VVR08_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6075849.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHALDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNILG
                     NACKNAK"
     gene            1046..2053
                     /locus_tag="VVR08_002023"
     CDS             1046..2053
                     /locus_tag="VVR08_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6075850.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2053..3060
                     /locus_tag="VVR08_002024"
     CDS             2053..3060
                     /locus_tag="VVR08_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6075851.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3060..3854
                     /locus_tag="VVR08_002025"
     CDS             3060..3854
                     /locus_tag="VVR08_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075852.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT         1593 a          637 c          745 g         1415 t
ORIGIN      
        1 atagacttga aatatgttta aggagttttt atgaaaaaca aattttttct aatagctatt
       61 ttagctatgt gtatagtttt tagcgcttgt tcttctaatt ctgttaaaaa tgaagaaaat
      121 acttctaaag agcatgcgct tgataaaata gttttagatc atgctttcgg tcaaactata
      181 ttagataaaa aacctgaaag agttgcaact attgcttggg gaaatcatga tgtagcatta
      241 gctttaggaa tagttcctgt tggactttca aaagcaaatt acggtgtaag tgctgataaa
      301 ggagttttac catggacaga agaaaaaatc aaagaactaa atggtaaagc taacctattt
      361 gacgatttgg atggacttaa ctttgaagca atatcaaatt ctaaaccaga tgttatctta
      421 gcaggttatt ctggtataac taaagaagat tatgacactc tatcaaaaat tgctcctgta
      481 gcagcataca aatctaaacc ttggcaaact ttatggagag atatgattaa aattgattca
      541 aaagccttag gtatggaaaa agaaggtgat gagttaatca aaaatactga agctcgtata
      601 tccaaagaat tagaaaaaca tccagaaatc aaaggaaaaa tcaaaggaaa aaaagtatta
      661 tttactatga ttaatgctgc agatacatca aaattctgga tttatactag caaagatcca
      721 agagcaaatt atttaacaga tttaggtcta gttttccctg aatcattaaa agaatttgag
      781 agtgaagata gttttgcaaa ggaaatttct gcagaagaag caaataagat aaatgatgct
      841 gatgtaatca taacttatgg tgatgataaa actcttgaag ctttacaaaa agatcctctt
      901 ttaggtaaaa taaatgcaat taaaaatggt gccgttgctg taattccaga taatacaccg
      961 ttagcagcct catgcactcc aacaccactt tcaataaact atactattga agaataccta
     1021 aatattttag gaaatgcatg caaaaatgcg aaataaaaaa caaataaacc taggcataat
     1081 ttttgtaatc tgcctaggtc ttcttattac aatatttttg tcattaaagc ttggaacaaa
     1141 agaaattaat atcagagatt ttttagcagc ttttggaatg ggcaatacaa atgatgattt
     1201 tattaaatca attatatata aaagaatacc tagaactatt tttgcaattt tagcaggttc
     1261 tagtcttgcc ataagcggtg tattgatgca atcagttact agaaacccaa tagctgatcc
     1321 aggtatactc ggtataaaca caggagcaag tcttagtgta gtaattggtc tttctttttt
     1381 aggaatttca tcaagcataa gccatataag ttttgcaatc attggtggct tagtaagtgc
     1441 aatttttgta tacgcgattg ctgtaagcgg aaaagcaggc cttaccccta taaaactagc
     1501 cttatcagga acttgtgtta gtatggcttt aagcagtttt gtaagttttt taattttacc
     1561 gaataataac gtcttagaca aatttagatt ttggcaaata ggtagccttg gagcagctac
     1621 attatcttct atatctacac tactaccttt tataatttta ggtcacttga tagctatatt
     1681 tatttcatca gatttaaacg ctttagctat gggtgatgaa atggctgttg gtcttggagt
     1741 taatgttaat aggataagat cacttgcaat aattgcaagt gtgcttttat gttcaagtat
     1801 tactgcaatt ggtggaccta ttggcttcgt aggtcttata gttcctcact tttgtggctt
     1861 atttataagc aaagatatac gcacaatgac catttcttca tcttttatag gtgcagagct
     1921 cttgcttata tgtgatataa tcggccgtat gttaggtaaa ccaggtgaaa ttgaagtagg
     1981 gataattact gcaataatcg ggggtccagt acttatttat gtaactatga aaaatagagg
     2041 ggttaataac taatgcaaaa tttaattata ggtattcaaa aaagaaaaaa tagaataaca
     2101 ctattttcct cactattttt attaataata atcagtctat catttttcat tttacttatc
     2161 ggagatgaaa gttattcttt ttcaactttg attaaagtct taaatagtga aactgttcct
     2221 ggagctagtt tttcgattat ggaaattaga ttaccaaaat tattagcagg aattatagct
     2281 ggctggtctt ttggattggc aggatttatc tttcaaacta tgttaagaaa tcctcttgca
     2341 agtcctgata taatcggtgt cacaagttct tcatctattg cagcggtctt ttgcatattg
     2401 gtattaaaaa caaatagttt aactactgga attatttcaa taacttgtgg actaacatca
     2461 tctttaatat tatttttact agctaaaaaa gatggttttt cagcagcaag actgataata
     2521 ttaggtattg gttttcaagc tgtcacaaga gcaggcacct catttttatt gttgaaagta
     2581 gcaagatatg aattacaaga agttatgaga tggctcagtg gctctttatc ttttacaaag
     2641 ttagatgaca tacctcttgt tctaatagta agtattattg ctactatatt agttttattt
     2701 tttaataaaa gactagaaat tattgaactt ggtgaagaaa tagcaatcgg acttggagca
     2761 aatcccgagc tttcaaggct tgttttaatt ttttgcgctg tatctttaac tgctttttct
     2821 acttcaatta caggaccaat agcttgtata tcttttttag ctggtcccat agccttaaat
     2881 attggcaaga aaagaagccc aatattagct ggattggttg gaattttact agttttgtta
     2941 tcagacatat tctctcaaaa tattttacca gctagatatc cagtaggtgt tgtaactggc
     3001 ttgttaggtt caccatactt aatatactta ctaataaaaa tgaacaggag gaatatataa
     3061 tgaaaggtct gtggtcaaat aatcttacct gcggttatga tgaaaaaata atcttggaaa
     3121 atataaatat aaaaatacct gaagaaaaaa tatcagttat tattgggtca aatggttgtg
     3181 ggaaatcaac actcattaaa accttgtctc gacttataaa gccattagag ggagaagtat
     3241 tgcttgataa taaatcaatt aattcttata aagaaaaaga tttagcaaaa cacatagcta
     3301 tattacctca atctccaata atccctgaat caataacagt agctgatctt gtaagccgtg
     3361 gtcgtttccc ctacagaaag ccttttaaga gtcttggaaa agatgacctt gaaataataa
     3421 acagatcaat ggttaaggcc aatgttgaag atctagcaaa taacctagtt gaagaacttt
     3481 ctgggggtca aaggcaaaga gtatggatag ctctagccct agcccaagat acaagtatcc
     3541 tacttttaga tgagccaact acttacttgg atatctcata tcaaatagaa ctattagacc
     3601 tcttgactga tctaaaccaa aaatataaga caaccatttg catgattttg cacgatataa
     3661 atctaacagc aagatacgct gattacctat ttgcaattaa agaaggtaaa cttgttgcag
     3721 agggaaagcc tgaagatata ctaaatgata aactagttaa agatatcttt aatcttgaag
     3781 caaaaattat acgtgaccct atttccaatt cgcctctaat gattcctatt ggcaagcacc
     3841 atgttaactc ttaataattg aatattggaa ttcatttaaa agtcgcaaat tttgaactga
     3901 ccctcaaaag ttaggccaaa aaactaacta aaggaggtca gttttttaat ggcaaataca
     3961 gcacagaatt taagataaaa ttagtaaaag aatatcatga atgaaaaata ggatatagag
     4021 aataacagca atattaaaaa gatcaggact gataataaac aaaaagaaag tacaacgact
     4081 agttcaaaag ctaaaacttc aagtaaaaag ttattcaaga aaatctagaa aatactcatc
     4141 ctacaaagga caggtaggaa aaatatcaga caacaaaata aaaagaaata tttattaccg
     4201 aaaaaaaggg aaaatcgagt caagtaccaa caggctcatc tattccaaaa agatatttac
     4261 tcgatggaaa aactcctaga attagtgcta caaatattga caatggtatc ttaggttact
     4321 acgaagatat agatgataaa aattatagag tttttgaaaa ttttatatct gtttcatttt
     4381 taggagcagt
//
LOCUS       DAVHSH010000091         4314 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000091 DAVHSH010000000
VERSION     DAVHSH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.092"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(128..1000)
                     /locus_tag="VVR08_002026"
     CDS             complement(128..1000)
                     /locus_tag="VVR08_002026"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU6075853.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1237..2547
                     /locus_tag="VVR08_002027"
     CDS             1237..2547
                     /locus_tag="VVR08_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU6075854.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(2913..3107)
                     /locus_tag="VVR08_002028"
     CDS             complement(2913..3107)
                     /locus_tag="VVR08_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6075855.1"
                     /translation="MKGKKYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     LSSGVTLITGKNGTGKSTLL"
     gene            complement(3568..4296)
                     /locus_tag="VVR08_002029"
     CDS             complement(3568..4296)
                     /locus_tag="VVR08_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6075856.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
BASE COUNT         1342 a          910 c          693 g         1369 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctatatttga agaggcgttt
       61 aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag ttagtttatt
      121 ttacaactta gacatcaaga taggttaacc ccttcatgga aaaatcaaga ctcttagcac
      181 tatgggttaa actaccactg gagacataat caatcgctaa accacgaaaa cggctaatag
      241 tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt agggtaatgg
      301 cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcagca cccgccgccg
      361 cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc acaaaaggag
      421 cataggcacg cgcttgagca attgcctttt gaacactacc tactgccgca atgtgattgt
      481 cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg ccaactctca
      541 cggcatattt ctcaaaaaga cgtaaattag gagtagtttt tcgagtatca aataccttaa
      601 tgcaatcatc gtctaaggct tctacataag cagctgtcat cgaagcaatc cctgataaat
      661 gttgtaaaaa attcaaggca acgcgttcac atgttaagag acttctcacc gagcctatga
      721 tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga tgaggattct
      781 ggaaggtcac ctcggcatca aatagggtaa aaaccctttt aaaaacggtt agccccgcta
      841 aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga tcaaaaatgg
      901 cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc aatgtatcat
      961 ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc tctattttta
     1021 atatcacttg taagcattag aggcaatcac tattaacttc cataggaaat cacaagcctg
     1081 aatacctcat ttttaattct aacaagtgtc aatacaattg tcaagacaat tgtatttttt
     1141 ttgtgtataa tagtcaagta ccaataggaa acaggtggtc ttttgagcgc caaaattgcc
     1201 aacctatttc catattctaa ctgaaaggac aattcaatga ttcatttaat aatgattagc
     1261 gccattgctc tagccattgg aattggttac cgcaccaaaa tcaatattgg cctgctggct
     1321 attgcttttt cttacctcat cgcaaccact ctcatgggat taagccccaa agaacttctt
     1381 catttttggc caacctcact cttttttacc atttttagcg tctctctctt ttataacttt
     1441 gcaataacta acggtactct tgatgttttg gctcaacaca ttctctaccg cacacgcacc
     1501 taccctaacg ccctctacat gattttatac ctgatggcaa cccttttgtc tgctttaggt
     1561 gctggatttt tcactactat ggccgtttgc tgtcctctag cgattaccct ctgtcaaaaa
     1621 gcggacaaac accctttgat tggagctcaa gccgtcaatt ggggagcttc aggaggggct
     1681 aatttgataa ccagtagctc aggcattgtc tttcaaggcc tgtttaagca aatgggatgg
     1741 gaagagcaag ctttttcact tggcaatcat atctttatcg tcagcattat ctacccactc
     1801 atcgtcttgc ttttattatc ctgttacagt cactatagta agggaagaac aaactcatcc
     1861 ttgactattg accaaccacc actcctcagc aaggttcaaa gacaaaccac cttgctcatg
     1921 atcagcagca tggttttggt ttggcttttt cccttgttgc atctcatttt cccaaacatc
     1981 gcctggatag ctacttatca aaaaacattt gatattggct ttgtctcaat actcatggtc
     2041 tgcctcgcct taaggctcaa attagggaag caagaagcca ttttagctaa ggttccctgg
     2101 gctacaatta tcatgctctg cggcatgagc ttactaatgt ctctagcggt caagtcaggt
     2161 ttagtcacac tgatagggca cctcatgaca acaaccattc ctcatttctg gttacctctg
     2221 ttcttttgtg tgatagccgg agtgatgtca ctctttagtt ccaccctatc cgttgtagct
     2281 ccagccctct ttcccatcat tgctatcatc agtgctcaaa atcctcagat tgatattcac
     2341 ttactcacaa cagccaccgt tattggcgct ctatctacta atatctcacc cttttcatca
     2401 gctggttctc tcattcaact ctcacttccc aatatagagg aacgtggcct tgccttcaaa
     2461 aagcaaatta ttctgggtgt ccccatcagc ttaagtttgg gactcttgac cacctggatt
     2521 ctcatccttc tagcttcctt aagttagatt tattatctaa cttaagggtg gacttggtat
     2581 aataaagtag acacaaaatt aagtggaaac gaggaaaagt cattatgcca agaaaaacct
     2641 ttgataaagc cttcaaactc tctgctgtaa acctcatcct gtaaaaatga ttagttcaac
     2701 tttaaaaatt catcccaata gtctttatcg atggattcaa gaatatgaaa aatatgaaga
     2761 aagtgcgttc ccaggacatg ggagcgcact tcgtcatact caatttgaaa tatagtgaaa
     2821 tgaaataaga ccaggacaaa tagatcagga tagtcaaatc gatttctaac aatattttag
     2881 aagtagatgt gtactattct agtttcaatc tactatagta aagttgactt tcctgtacca
     2941 tttttaccag taattaatgt cacgcctgaa ctcaaagtat caaaagaaat attatcaaac
     3001 aatatacgat gatccaccct atacgaaata ttttctactt tcattttttc tccttttgaa
     3061 ctaatagcaa aagaaacagt tctgttttca tactttttcc ccttcatcta tattattcgt
     3121 aatgaaaaat aaaaaaaata aaattttttt aaatgattat gattcagaat ttatttaata
     3181 tattaaaaga agatatgaac aaataaattg ggagattgaa attcatttct agcaattttt
     3241 tagaagtcac agtctactat tctaacctca atatactata tgtgttacaa gaaaagactc
     3301 aaaaacttct cgtcagtgta agaatgtttg aaacactatt taaaactaaa taactataag
     3361 aagtagatca ggtgaacaat ttcagtacct actctataag ctatacgaag atatttttca
     3421 acatgatgga taaaacgatc actcttttaa agccatctta tttagaaaag agaaaccatt
     3481 taagcataga tgggaccttc ttgccctgtt ttaaattttt cttaaactag agcctgtaaa
     3541 agattggctt cattttcaca ttttctccta ggaggaatgt cgtaatgcaa aagaattaaa
     3601 ttcaaataaa tcatagcgat gacgactaat cgagtactca aacggagttc cgttatccaa
     3661 ataagccact tgttctactt caaataccgg ttccgttgga aggagctgca agtaatgttg
     3721 ctcattttct gaactagaag aagctcgtaa gatttttgta gcactggcaa tatgcaatcc
     3781 taattttcct tcaatgtaat tgtaaatcga tttttgtaaa atatcttcag taatacctgg
     3841 aataacatcg gtactcatat aagtttgttc cagaacataa ggtttaccgt caataatacg
     3901 caggcggtaa atattataaa ctggactctg caaagcgacc tgtagttttt ctgctaaaaa
     3961 ttcatttgca aattctaatt tgaagtgaat aatcctcgag tcaattgtag aatgagcatc
     4021 ttcagatatt tttgtcagtc cccggatatc tctttctgga acgattaatt ttctttttga
     4081 gctgccacga gagagaacaa aggttccctg cccacgtttt ctaaaaatta agccctcaga
     4141 aactaacaag tctaaagctt ttttgatcgt cattcgacta caggcaaact gtttagctaa
     4201 tgtcatttca tcaggcaatt gttcgttcat ggtatattta ttacaaagaa tcttttcacg
     4261 aatctcattg taaataaata aatattttgt actcatttaa tctggttctc tcta
//
LOCUS       DAVHSH010000092         3861 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000092 DAVHSH010000000
VERSION     DAVHSH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3861
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.093"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..408
                     /locus_tag="VVR08_002030"
     CDS             <1..408
                     /locus_tag="VVR08_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU6075857.1"
                     /translation="KPQTEKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLYKPS
                     TDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLTGLK
                     SSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
     gene            618..3737
                     /gene="phtE"
                     /locus_tag="VVR08_002031"
     CDS             618..3737
                     /gene="phtE"
                     /locus_tag="VVR08_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU6075858.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1444 a          632 c          751 g         1034 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgatgaagat aagggacatg atgaagtaag tgagccaact
       61 caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc agataatctt
      121 tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac tacagatgag
      181 gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga tgcggaggcc
      241 ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac attgactggt
      301 ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc agaagtagat
      361 agtctcttgg ctttgttaaa agaaagtcaa ccggctccta tacagtagta aaatgaatgg
      421 agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa aaacgtaaca
      481 gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta aatggttaaa
      541 taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac ttcatcattt
      601 attgaaatga gggatttatg aaatttagta aaaaatatat agcagctgga tcagctgtta
      661 tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag gaaaataagg
      721 acaataatcg tgtctcttat gtggatggca gccagtcaag tcagaaaagt gaaaacttga
      781 caccagacca ggttagccag aaagaaggaa ttcaggctga gcaaattgta atcaaaatta
      841 cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat gggaaagttc
      901 cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat caacttaaag
      961 acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat ggaaaatatt
     1021 atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat gaaatcaatc
     1081 gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt gctgtagcaa
     1141 ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct gatattatcg
     1201 aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac attcccaaaa
     1261 gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga aaaaatatgc
     1321 aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa tctgtagcaa
     1381 aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt ttgaaggaac
     1441 tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc tttgaccctg
     1501 ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac cattaccact
     1561 ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg gtgcctatca
     1621 gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg tctagtctag
     1681 gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct tcagcatctg
     1741 atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct tatattgtaa
     1801 gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa ccgactcttc
     1861 caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga acttcacatg
     1921 agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct gaagatgaat
     1981 caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag gacttgacag
     2041 aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt cataatggat
     2101 tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa atgaaagatt
     2161 tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt gtcaaacgtg
     2221 aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga gatcaccatc
     2281 atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac agtaactatg
     2341 aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt tatactggag
     2401 aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat caaaacttta
     2461 ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg gagaaaaaat
     2521 taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg gagaaagtat
     2581 ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta gatcaacctt
     2641 atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca gaagtaagtt
     2701 atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt caaacgattt
     2761 tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt gcagtgccta
     2821 aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct tatttagaaa
     2881 ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa ggaacaacca
     2941 gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg gacaatcaat
     3001 cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat aaaccaagta
     3061 ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat gaaaaggtag
     3121 aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact gggaatagta
     3181 ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa aaagtagcaa
     3241 aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg gacggaacaa
     3301 ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat tttacaggag
     3361 aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta tctactggaa
     3421 cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag gcaccaaacg
     3481 aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca gaagggaatg
     3541 tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta gatcctgtac
     3601 aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt gttatattca
     3661 atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa aagaatttgt
     3721 ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat gaagttctct
     3781 caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt aatatataaa
     3841 atttcttgac atacaactta a
//
LOCUS       DAVHSH010000093         3607 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000093 DAVHSH010000000
VERSION     DAVHSH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.094"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            52..579
                     /locus_tag="VVR08_002032"
     CDS             52..579
                     /locus_tag="VVR08_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6075859.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            656..1012
                     /gene="glnR"
                     /locus_tag="VVR08_002033"
     CDS             656..1012
                     /gene="glnR"
                     /locus_tag="VVR08_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU6075860.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            1049..2395
                     /gene="glnA"
                     /locus_tag="VVR08_002034"
     CDS             1049..2395
                     /gene="glnA"
                     /locus_tag="VVR08_002034"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU6075861.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2485..2604)
                     /locus_tag="VVR08_002035"
     CDS             complement(2485..2604)
                     /locus_tag="VVR08_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU6075862.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            3092..3607
                     /locus_tag="VVR08_002036"
                     /pseudo
     CDS             3092..3607
                     /locus_tag="VVR08_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         1135 a          622 c          718 g         1132 t
ORIGIN      
        1 actcataaaa atcaccgatt tatgataaaa tggaaataga aagttgagat tatgagttat
       61 tttaaaaaat ataaattcga taaatcccag ttcaaacttg gtatgcgaac ctttaaaaca
      121 ggtattgctg tttttctagt tctcttgatt tttggctttt ttggctggaa aggtcttcaa
      181 attggtgctt tgacagccgt ttttagcctg agggagagtt ttgatgagag tgttcatttt
      241 gggacttcgc gtattctagg aaatagtatc ggtggactct atgccttggt cttcttctta
      301 ttaaatacct ttttccacga agccttttgg gtgaccttgg tagttgttcc aatctgcacc
      361 atgttaacca ttatgacaaa tgtagccatg aataacaaag caggggttat tggtggtgta
      421 gcagctatgt taatcattac cctatcaatt ccaagtggtg agacaatttc gtacgtgttt
      481 gtgcgtgtat cagaaacgtt tatgggagtt tttgtcgcaa ttatcgtaaa ttacgatatt
      541 gatcgtattc gtctcttttt agagaaaaaa gaaaaataat gttacatttt ataacattat
      601 caattgacgt ttgtcttttt ttagactata atagacagaa agaaggaaat tgtaaatgaa
      661 ggaaaaagaa tttcgccgaa atatggctgt ttttcctatt ggcagtgtta tgaagttgac
      721 cgatctatcg gcgcgtcaga ttcgttatta tgaagatcaa gagttgatca agcccgatcg
      781 aaacgaagga aatcgtcgca tgtattcctt gaatgacatg gatcgtctgc ttgaaatcaa
      841 agattatatc tctgaaggtt ataatatcgc tgccattaag aaaaaatatg ctgaacgtga
      901 agcgaaatcc aagaaagcgg ttagtcagac tgaagtacgt cgtgcacttc acaatgaact
      961 cctccaacag gggcgctttg cttcagtaca gtcacctttt ggtcgcggtt aggcaaccgc
     1021 aagtagtcat agattaagga gaaaacttat gccaatcaca gctgcagata ttcgtcgtga
     1081 agtcaaggaa aaaaatgtta cctttattcg tcttatgttt tcagatattt tgggaaccat
     1141 gaaaaacgtc gaaattcctg ctacagatga acagttagat aaggtcttgt cgaacaaggt
     1201 tatgtttgat ggatcttcta ttgaaggttt tgtacgtatc aatgagtcgg atatgtactt
     1261 gtacccggac ttggatacat ggacagtctt cccttgggga gatgaaaatg gaagtgttgc
     1321 aggtctgatc tgtgatgtct atacaacaga aggtgaacca tttgcgggtg accctcgtgg
     1381 taatttgaaa cgagctcttc gtcacatgga agaagttgga ttcaaatcct tcaaccttgg
     1441 tccagagcca gaattcttcc tatttaagtt ggatgaaaat ggggacccaa cacttgaagt
     1501 gaatgacaag ggtggctact ttgatttggc acctactgac cttgcggaca acacacgtcg
     1561 tgagattgtg aatgtcttga ccaaaatggg atttgaagta gaagcgagtc accacgaggt
     1621 tgcggttgga cagcatgaga ttgactttaa gtacgatgaa gttctccgtg cttgtgataa
     1681 gattcaaatc tttaaacttg ttgttaaaac cattgctcgc aaacacggac tttacgcaac
     1741 atttatggcg aagccaaaat ttggtattgc tggctcaggt atgcactgta atatgtcctt
     1801 gtttgatgca gaaggaaata acgccttctt tgatccaaat gatccaaaag gaatgcagtt
     1861 gtcagaaaca gcttaccatt tcctaggcgg tttgatcaag catgcttaca actatactgc
     1921 catcatgaac ccaacagtta actcatacaa acgtttggtt ccaggttatg aagcgcctgt
     1981 ttacattgct tgggctggtc gtaaccgttc gccacttgtg cgcgtacctg cttcacgtgg
     2041 tatgggaact cgtcttgagt tgcgttcagt ggatccaatg gcgaaccctt acattgctat
     2101 ggctgttctt ttggaagttg gtttgtatgg tattgaaaat aaaatcgaag caccagctcc
     2161 tatcgaagaa aatatctaca tcatgacagc agaagagcgc aaggaagctg gtattacaga
     2221 ccttccatca actcttcaca acgctttgaa agctttgaca gaagatgaag tggttaaagc
     2281 tgctctcgga gatcacatct acactagctt ccttgaagcc aaacgaatcg aatgggcaag
     2341 ttatgcaacc ttcgtttcac aatgggaaat tgataattat ttagaccttt actaatatag
     2401 aagaaagatt gcctgtgggt aaacagtcac acagcagtct aagccatcaa atacctataa
     2461 cccttaaaat agcgatttcg gtcgctattt atttttcgaa aaatcctctt gactcttttg
     2521 cgaattagat ttatcatcag acgtgtagaa gaaaatcaag gagtcactat ggaaaaattc
     2581 aatttcaaaa acaatatcgg gcaagaaaac aagttacttc aaatcgaaat ctacaagttt
     2641 actaactttt gcaagcttca aaattacaca tctgtaaata ttttttcgaa agatatattt
     2701 gaagccatag taaattgaga ctagaatagt acactacatc tgttaaaaat ttctagaaac
     2761 taatttaact ttcctaatcg atttgtttac atcttatttc aatctactat attatctcaa
     2821 taaatgatga tggcgactgt tttgtttgtg cttgtcgatt tttgaatcct gatcgagcgg
     2881 aagaatattt ctgccgaggt tgccaagggg aaaatcctga agatattgaa ttttatgatg
     2941 aacaattaca ggcagaaaag gtggaggttt tgaatattcg attggaagta aaaaattgaa
     3001 ttatctacaa tctcatcaac aataaaccta tttcaacccc attatctata ggcgtatttt
     3061 tacgcctttt tatatacttg aagcacataa gaaacattat gggaagtttg ctgatggaag
     3121 cactcaagaa attgatgttc cttatgatat tcctgatact tgggagtggg tgaggataaa
     3181 atcaatttat tggaattttg ggcaaaataa gccagagaaa tcctttaggt atatagatac
     3241 gtctagtatt gatagaaaaa agaacataat caactacaaa aatctacaat atctttcacc
     3301 tgaacaagcg ccttcccgtg ctagaaaatt agtttcgcag aatagtgtct tattttcaac
     3361 agttagacca tatctaaaaa atattgctgt agttagagaa cttaaagagt atttgatagc
     3421 tagtacagca tttattgttt tggatacttt acttaacgaa acatatttga aatattattt
     3481 attatcagat aattttatca atcgtgttaa taataaatct actggaacaa gttatcctgc
     3541 aatcaatgat tataatttta atctattatt aattgctctc cccccactat ccgaacaaca
     3601 acgaata
//
LOCUS       DAVHSH010000094         3367 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000094 DAVHSH010000000
VERSION     DAVHSH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3367
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.095"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..129)
                     /locus_tag="VVR08_002037"
     CDS             complement(<1..129)
                     /locus_tag="VVR08_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6075863.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKE"
     gene            complement(315..926)
                     /gene="rpsD"
                     /locus_tag="VVR08_002038"
     CDS             complement(315..926)
                     /gene="rpsD"
                     /locus_tag="VVR08_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU6075864.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1121..2173)
                     /locus_tag="VVR08_002039"
     CDS             complement(1121..2173)
                     /locus_tag="VVR08_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6075865.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2170..2868)
                     /locus_tag="VVR08_002040"
     CDS             complement(2170..2868)
                     /locus_tag="VVR08_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6075866.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3035..>3367)
                     /locus_tag="VVR08_002041"
     CDS             complement(3035..>3367)
                     /locus_tag="VVR08_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6075867.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT          944 a          756 c          643 g         1024 t
ORIGIN      
        1 ctcttttagc tttaaccagc cataaatggt attacgtgag atttggaaaa cgtgtgatgc
       61 ttctgttata ctacctgttc gctcacaata agagagaact tttttacgaa aatctattga
      121 atatgccata aaaggattat accacattgt gtactatttt tggttcattt tactatatca
      181 ctttggacta tatcggtcta gttatgtctc aacgattata gctggatact aagagaaatc
      241 aaaaaagcac taagggagaa cgtcccaaag tgcttaatat caaggcctca aagcctatct
      301 tattcaataa aatattacaa cattttgttg tagaattcaa cgacaagtgc ttcgttgatt
      361 tctgggttga tttcgtcgcg ttctggcaag cgagtcaatg aaccttccaa cttttcagcg
      421 tcgaatgata cgaatgctgg acgtccaaga gtagcttcta ctgcttcaag gattgctgga
      481 actttcaatg atttttcacg aactgagatc acttgacctg gagttacgcg gtatgatggg
      541 atatcaacgc gtttcccgtc aacaaggatg tgaccgtggt ttacgaattg acgagcttga
      601 cgacgagtag tcgcgagacc aagacggtaa acaacgttat ccaaacgacg ttccaaaaga
      661 agcataaagt tgaaacctag gattccgcct ttgatttttg tagcttgtac gaacaagtta
      721 cggaattgtt tttcacctac accgtaagtg aaacgaagtt tttgtttttc agccaattgc
      781 aaaccgtatt ctgacaattt agaacggttg tttggtccgt gttgtcctgg tacgtagtta
      841 cgacgtgcca attctttacc tgtacctgta agtgaaaggc caaggcgacg agcttgtttc
      901 caagatggtc ctgtataacg tgacatatga atgtcctcct gatataaata atatttcggt
      961 ggaaatagtc acttagaaag ccctgattcg tgcagatgcc cttcgcctaa acagccaagg
     1021 ttacttgtca taagacacct gttgacgagc ttcatgcttt cctgctgata tttcacacaa
     1081 aatctattct accatgaata gctggatttg taaaggggtt ttaggcttta ttttcactac
     1141 cagagaggtt gagaacgagg gtaaaggtac ttcctagacc gtactggctg ctgactgtga
     1201 tttccccacc caattgatgg gccaattcac gcgcaatcgc aagtcctaat ccatgaccac
     1261 ctgtcttcat gttacgcgaa gtttcgacac gataaagacg tttgaaaata ttttccaaat
     1321 cctctggggc aataccctgc ccttcatcgg tcacactgat tgaaagctgg tccttctcca
     1381 gcttagccac cacttccagc ttggttcctg gagcagaata tttaaaagcg ttatcgacca
     1441 gattcaccaa gatacgagaa agcttagcat aatctccctc aatccgggca gactctggga
     1501 ttacctgcaa gtggacatct cttctctcct gctcaatcaa aaactgaaat tcactcatgc
     1561 actcaattaa gagcttgtcc agaaaaatac tgtctttact ggtagtttcc acctgatttc
     1621 tagctgtgtt tagggtcaaa aaattcaact cctcaaccag tttattgagc ctctccgtct
     1681 ggcgtccaat ggttgctaga taatgagctt gctccgactc cttgataatc ccatccaaaa
     1741 tcccttctac cgtcgcttga atcgaagtga taggggtctt aatatcatgc gacaactggg
     1801 caatcatcaa gcccttttct cgttcgcttt cttccaagga atcaaagctt acctgcaaat
     1861 catgggacat ctcattaaaa gtttgcccta attgctgaaa ttccacagga ccttgaacct
     1921 ccaaatttga aggaaaatcc ttggccgcta cccgcttggc atgctccttg agtttgccca
     1981 acgacgtaaa gactggcaat aggagaaaga gactaatccc agcaccgaca aggctggcaa
     2041 cgatggtcat cccaagcaaa aagtaaatct cgcctttcgc aatcagcatt ttttgaacag
     2101 cccaaaaaac aaccaaaatg gttaagaggg ttgaaataat atatccaacc aaaatataac
     2161 tttttagttt catgtttgtc ctctcggttt ctctatctta tatcccaacc cccaaactgt
     2221 cttaatagtg ggcgtttggt cactactata ttttgccagc tcctgtcgaa gagcatggat
     2281 atgcacattc aaggtattgg tgtcatccac gtagtcttct ttccagatct tttcatagag
     2341 gtctgtcttg gagaaaactc gctctggatt gctagctaaa atccacagca attcaaatga
     2401 tttaacagtt aaatccagca tttcttctcc tatttgaact tcatgactac tatgattcat
     2461 ttttagattg ccaagggaaa tcagctctgt ttcgccccca cgatgaaggc ggcgcaaaat
     2521 attgtggaca cgcaaaacca gctcacgtgg gctaaaaggc ttagcaataa aatcatctgc
     2581 tcccaagctc aggccgtaaa tcttgtcctg ttcactggtc ttagcagtaa taaataggaa
     2641 aggctgctct ggtgataagt attgaacctc actgattaaa tcataaccat ccatccgagg
     2701 catcatgaca tctgtgataa tcaaatcaat cggttttttc ttgaacagct ctagcgcttc
     2761 cagtccatca tgggctacca agacctgata acctgcctga attaagtatc tctgatgaat
     2821 atctgtgatt tctacctcgt cgtcaacgag taaaattgtc tttcccatct gtctctcctt
     2881 tgataaaaac agtgctatac tgctttaagt ataacactat ttttattgtt ttacgatgat
     2941 tttaatctgc tattgaaaga aagtcctgat tgctgattga gttgttaaac taatcttagt
     3001 cagcccacta tccatcattt atttccttag ctgattagtt ttcttctttt ttgtttttca
     3061 aacctagacc accgagtaaa cctgcaagcg caagcccaag gaaaccaata cttgccattg
     3121 atgtttgagt ctcaccagta tttggtagca tagctttatc ctctgacatc atcgtatcag
     3181 acatcttgtt agcagaagca gccatgtttt cacctgccat cgtgttggta gaacttgtca
     3241 tggtgtcagc aggcatgcta tctgtagtac ctgtagcatg attgtgattc atcggagtca
     3301 cgccagaacc agagttagaa ggtgataatg aaccatttgc tgtgtctgat gtttctttaa
     3361 catttat
//
LOCUS       DAVHSH010000095         2977 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000095 DAVHSH010000000
VERSION     DAVHSH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.096"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(166..699)
                     /locus_tag="VVR08_002042"
     CDS             complement(166..699)
                     /locus_tag="VVR08_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU6075868.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(788..1564)
                     /gene="recX"
                     /locus_tag="VVR08_002043"
     CDS             complement(788..1564)
                     /gene="recX"
                     /locus_tag="VVR08_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU6075869.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1602..2957
                     /gene="rlmD"
                     /locus_tag="VVR08_002044"
     CDS             1602..2957
                     /gene="rlmD"
                     /locus_tag="VVR08_002044"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6075870.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVSKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          941 a          532 c          539 g          965 t
ORIGIN      
        1 acagtatatc tatttgtttt atatatttta cgaattttgt ataaatctct ttctagtaat
       61 gtgttgtaac tctgctataa tagatttatt cctttttgtg tttacacaat ttattttata
      121 ctaccaaaaa aaaggtcagg attttgttcc tgacctttga caactttacc gattctttag
      181 ttctacatag cgcttgtacc aaatgtttac ataggcttct gagaaaggac cacgtccatt
      241 gttaatccaa tcaacaagaa ttttgacatg ttcttttaaa atatagtcca agtcatcaga
      301 ataattcatt ttgcgtttgt gacgctcgta ctcttcaacg tccaagagac gtttttcccc
      361 atctgtaaaa attttaacat ccaaatcgta atcaatatac ttcagtgctt cttcatccag
      421 atagtagggg ctagccatat tgcaatagta agaagttcca ttatcacgaa tcatggcaat
      481 gatattaaac caatatttct tgtgaaagta aacaatagcc ggttctcgag tgacccaacg
      541 acgaccatca ctttcggtaa caagtgtatg atcgttgaca ccaataatgg cgttttctgt
      601 tgtttttagt accatggtgt cccgccaagt tcggtggaga ctcccatcat gcttataact
      661 ttgaattgta ataaagtcgc cttcttttgg aagcttcata actaaccaac tttctacaat
      721 ttataagttt atcatttact attgtaccat aaaattacct aaaatctgtg aatttcactt
      781 ggaaatatta aagatattct ctaagagcgc ttgctatatc cgaaaaatcg tagccctttc
      841 gtgctaaaac ttgagttaaa cgctgcttca gttcgtatcc ttcatacttt cgagcatact
      901 tagtatattg cttatcaagt tccttgaaga tgagttcttg agtcgtttct tggtcaactt
      961 ggctatctaa gtcgtcaaag gcaattttag catcagaata agagaagccc ttgttagtca
     1021 agttctggat aatcttatct tgcagggcac gagctggaag ttttccctca tattttttca
     1081 atagtttatt ggctacacgt tgagcaactt ccgaaaaatc aaaatcattc aagatttctt
     1141 ctatagtaga ttttgaaatt cctttttgtg ctaatttctg agtcagtaca taaggtccct
     1201 tgtctcctga aagttgattg gcattgatga tagcataagc gtactgacca tcattaatcc
     1261 acttatcttc tttaagatta gcaataactt gagaaacgat gtttttatca atatcgtatt
     1321 ttttcagata ttctctgact tctttttcag tgcgtgcttt aaaggataag tggtagaggg
     1381 ccagattctt accataagaa aattgagcaa agtcttgaat ctctttcaat tcctcttcgc
     1441 ttatcacctt atctctcgat aacataaaac gaacaattgt atcttcggtg atatagcatt
     1501 tgtcgccatt atcaagctcc atcagataga gtcttttttt cttttcaagt tttgtgattt
     1561 tcatagctct attataactc aaaatgtgat aagatagggg tatgaatctg aaagtgaaac
     1621 aaaaaatacc attaaaaatc aagcgcatgg gaattaacgg tgagggaatc ggcttttacc
     1681 aaaaaacatt agtctttgta ccaggagctc tcaaaggcga agatatctat tgtcagatta
     1741 cttctattag acgcaacttt gttgaagcaa aattactgaa ggtcaacaag aagtctaaat
     1801 ttcgaattgt gccatcttgt actatttata atgaatgcgg aggctgccaa atcatgcacc
     1861 tgcattatga taagcagctg gagttcaaga cggacttact tcatcaagcg ctgaaaaaat
     1921 ttgctcctgc aggatatgaa aattatgaaa ttcgtccaac tattggaatg caggaaccaa
     1981 aatattacag agctaagtta caatttcaga cccgaaaatt taaaaatcag gtcaaggcgg
     2041 gcttatatgc acaaaactct cactatttag tagagttgaa agactgcctg gtacaagata
     2101 aggaaaccca agtgattgct aatcgcttag cagaattact tacttatcac cagattccaa
     2161 tcacggatga gagaaaagtt ctaggtgtcc gtactattat ggtccgacgc gcgagaaaga
     2221 ccggacaggt tcagattatt attgttacaa accgccagct taatttaact caattggtaa
     2281 aagagttggt taaagatttc ccagaagttg tgacagtagc tgttaataca aatacagcta
     2341 aaaccagtga gatatatggt gaaaagacag agattatctg ggggcaagag agtattcaag
     2401 aaggtgtact caattatgaa ttttcactat cccctcgagc tttttatcaa ctaaatcctg
     2461 aacaaacaga agtcctttat agcgaggcag taaaagcgct ggatgttagt aaagaagacc
     2521 atttgattga cgcttattgt ggagttggaa caattggttt tgcctttgca aagaaagtaa
     2581 aaacactcag aggtatggat attattccag aagctattga agatgccaag cgaaatgcta
     2641 aaagaatggg atttgacaat actcattatg aagctggaac ggcagaagag attattcctc
     2701 gttggtacaa ggaaggctac cgagcagatg ctttgattgt tgacccacca cgtacaggtc
     2761 tggatgataa gttattagat actattctta cttatgtacc agaaaaaatg gtttatattt
     2821 cttgtaatgt ttcgaccttg gctcgtgatt tggtacgctt agtagaagtc tatgatcttc
     2881 attatattca gtcggtcgat atgttcccac atacagctcg aactgaagct gttgtaaaat
     2941 taataaaaaa agtttaaaaa aggtgttgac aaaacat
//
LOCUS       DAVHSH010000096         2680 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000096 DAVHSH010000000
VERSION     DAVHSH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.097"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..1214
                     /locus_tag="VVR08_002045"
     rRNA            <1..1214
                     /locus_tag="VVR08_002045"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1266..1338
                     /locus_tag="VVR08_002046"
     tRNA            1266..1338
                     /locus_tag="VVR08_002046"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1299..1301,aa:Ala,seq:tgc)
     gene            1463..>2680
                     /locus_tag="VVR08_002047"
     rRNA            1463..>2680
                     /locus_tag="VVR08_002047"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          751 a          554 c          791 g          584 t
ORIGIN      
        1 acggcccaga ctcctacggg aggcagcagt agggaatctt cggcaatgga cggaagtctg
       61 accgagcaac gccgcgtgag tgaagaaggt tttcggatcg taaagctctg ttgtaagaga
      121 agaacgagtg tgagagtgga aagttcacac tgtgacggta tcttaccaga aagggacggc
      181 taactacgtg ccagcagccg cggtaatacg taggtcccga gcgttgtccg gatttattgg
      241 gcgtaaagcg agcgcaggcg gttagataag tctgaagtta aaggctgtgg cttaaccata
      301 gtaggctttg gaaactgttt aacttgagtg caagagggga gagtggaatt ccatgtgtag
      361 cggtgaaatg cgtagatata tggaggaaca ccggtggcga aagcggctct ctggcttgta
      421 actgacgctg aggctcgaaa gcgtggggag caaacaggat tagataccct ggtagtccac
      481 gctgtaaacg atgagtgcta ggtgttagac cctttccggg gtttagtgcc gtagctaacg
      541 cattaagcac tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg
      601 ggcccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag
      661 gtcttgacat ccctctgacc gctctagaga tagagttttc cttcgggaca gaggtgacag
      721 gtggtgcatg gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc
      781 gcaaccccta ttgttagttg ccatcattta gttgggcact ctagcgagac tgccggtaat
      841 aaaccggagg aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac
      901 acgtgctaca atggctggta caacgagtcg caagccggtg acggcaagct aatctcttaa
      961 agccagtctc agttcggatt gtaggctgca actcgcctac atgaagtcgg aatcgctagt
     1021 aatcgcggat cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca
     1081 caccacgaga gtttgtaaca cccgaagtcg gtgaggtaac cgtaaggagc cagccgccta
     1141 aggtgggata gatgattggg gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct
     1201 ggatcacctc ctttctaagg ataaggaact gcgcattggt cttgtttagt cttgagaggt
     1261 cttgtggggc cttagctcag ctgggagagc gcctgctttg cacgcaggag gtcagcggtt
     1321 cgatcccgct aggctccatt ggtgagagat caccaagtaa tgcacattga aaattgaata
     1381 tctatatcaa atagtaacaa gaaaataaac cgaaaacgct gtagtattaa taagagttta
     1441 tgactgaaag gtcagaaaat aaggttaagt taataagggc gcacggtgga tgccttggca
     1501 ctaggagccg acgaaggacg tgacaaacga cgatatgcct tgggtagctg taagtaagcg
     1561 atgatccagg gatttccgaa tgggggaacc caacaggtaa tacctgttac ccacatctgt
     1621 taaggatgtg aggaggaaga cgcagtgaac tgaaacatct aagtagctgc aggaagagaa
     1681 agcaaaagcg attgccttag tagcggcgag cgaaacggca gaagggcaaa ccgaagagtt
     1741 tactcttcgg ggttgtagga ctgcaatgtg gactcaaaga ttatagaaga atgatttggg
     1801 aagatcagcc aaagagagta atagcctcgt atttaaaata gtctttgtac ctagcagtat
     1861 cctgagtacg gcgggacacg tgaaatcccg tcggaatctg ggaggaccat ctcccaaccc
     1921 taaatactcc ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc
     1981 cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg agcccgttaa
     2041 tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgttatgat gcgaggttaa
     2101 gttgaagaga cggagccgta gggaaaccga gtctgaatag ggcgccttag tatcatgacg
     2161 tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgcggtaa gacgcactgg
     2221 aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc ggagaaattc
     2281 caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag cgtcgacatt
     2341 agagattctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     2401 agataaactc cgaatgccaa tgaattatgg tcggcagtca gactgcgagt gctaagatcc
     2461 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaataat tgttaagtgg
     2521 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     2581 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     2641 acaatttacc gaagctgtgg atacctttat aggtatggta
//
LOCUS       DAVHSH010000097         2648 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000097 DAVHSH010000000
VERSION     DAVHSH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.098"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..574
                     /locus_tag="VVR08_002048"
     CDS             <1..574
                     /locus_tag="VVR08_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6075871.1"
                     /translation="KIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIVAHRLSTIKDADVIFV
                     MKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            587..757
                     /locus_tag="VVR08_002049"
     CDS             587..757
                     /locus_tag="VVR08_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075872.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1263..2609)
                     /gene="gdhA"
                     /locus_tag="VVR08_002050"
     CDS             complement(1263..2609)
                     /gene="gdhA"
                     /locus_tag="VVR08_002050"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU6075873.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          852 a          455 c          513 g          828 t
ORIGIN      
        1 aaaaatacca tcaagattat ataagattga tacaggaaaa gttttatttg atggtgtaaa
       61 tattaatcaa atagataaaa aaatattaag tcaaaattta ggagtagttc cacaggattc
      121 atttttattg aaccgaagta ttcttgataa tataacttta aagcacgaag ttacttcaca
      181 aaagatagag gaagtttgta aagcagttca aatctatgat gaaatcatgg ctatgccgat
      241 gaaatttaat actatcatct cagagatggg gtcaaatatt tcaggtgggc aaaggcaacg
      301 gatagcactg gcacgtgcat taataaataa tcctagtatt gtaattttag atgaagcaac
      361 tagtgcatta gacactatta atgaggaaag aataacaaag tatatacaaa gtcagggctg
      421 tactcaaata attgtagctc atagattgtc aacgattaag gatgcggatg ttatttttgt
      481 aatgaaaggt ggtaagattg ttgagtcagg aaatcataag tacttaatgg atcttggtgg
      541 agagtactac agcttatata caaaaaggaa atgaggtgta aagaaaatga agaaagaaaa
      601 tgaatatgta attttaacaa cagcctcact aggggtgatg attggaatag tgtttgcaat
      661 ttttttagat tttccagttg aatatggtat ttctttaggc ttgttgaatg gaatagtatt
      721 gggttcgctg attgtttaca aaaacaataa gaattaagca taattttttg ctgtaaacta
      781 aggagtagag atggctatag ttgaaattat aaatctaaca aaaagcttta aagatattga
      841 agttattcat aacacttaaa taatagagca actacagtag tagcttaaaa acatgattaa
      901 atcgctattc ttaggagtag cggtttttct ttttgtttaa tactctttga aaatctcttc
      961 aaaccacgtc agctttgcct tgccgtaatc aagtacagcc tgcggctcgc ttcctagttt
     1021 gctctttgat tttcattgag tataaaaagg gttaagtaag tatagtaaat tgaaataaga
     1081 tatgaacaaa tcgattagaa aagtcaaatt aatttctaga aatatgttag aaattggttt
     1141 gaattccgca atcaatttgt tcagttttta ttgcatttca ttttatttaa ttagattttc
     1201 caatttttta attcaagcta aaaatcccca atcgtagtga ttgaggattg agtaaataaa
     1261 tcttaaacaa taccttgtgc aatcatggca tttgctacat tttcaaaggc agcaatgtta
     1321 gctcctgcaa ggtagtcttt atcaagaccg tatgtttctg aagtcgtttt agctgtgttg
     1381 aagatgtttg tcatgatgtc tttgagacgg ccatcaactt cttcacgagt ccatgagagg
     1441 cgaagactgt tttggctcat ttcaagagct gaaacggcta caccaccagc gttggcagct
     1501 tttgcaggtc cgtagaagat accattttct ttgtaaactt tgatggcatc aaggtcgctt
     1561 ggcatgttgg caccttcaga tacacagata acgccttgag caaccaaacg tttagctgct
     1621 tcaccgttga tttcgttttg agtggcacat ggaagagcaa tgtcatagtt tccagcgtaa
     1681 gtccatacag taccttcgtg gtaggttgca gttgcttttt cagctgcata ctcagtcaaa
     1741 cgagcacgac gtttttcttt aacatcaacc aaaagatcga agtcgatacc attttcatcg
     1801 atgacataac catttgagtc agaaacagaa ataacagttg caccgagttc agttgctttt
     1861 tgaagagcat attgagcaac gttaccagaa cctgaaataa cgactttctt accagcaaag
     1921 ctgttaccgt tagctttgag catttcttca gtatagtaaa ccaaaccgta accagttgct
     1981 tctggacgaa tcaagctacc accaaatcca agaggtttac cagtcaagac accagcatca
     2041 aattggttaa gacgtttgta ttgaccgtaa aggtaaccaa tttcacgtcc accaacaccg
     2101 atatcaccag caggtacgtc aagtgatggt ccgatgtgtt tttgcaattc agtcatgaag
     2161 ctttggcaga agcgcatcac ttcagcatct gttttacctt taggatcgaa gtctgatcca
     2221 cctttacctc caccgatagg aagtccagtc aagacatttt taaagatttg ttcaaatccg
     2281 aggaatttca agatcccttg gtttacagtt gggtggaaac gaagtccgcc tttgtatggt
     2341 ccaacagctg agttgaattg aacacggtaa ccgcggttta cttgaacttt tccatcacgg
     2401 tcaacccaag gaacacggaa agaaaccacg cgctcaggct cagtaatacg tgccaagata
     2461 ttttcttcga tatactcagg gtgtttttca aatacaggtt ctaaagtgtt gaaaaattct
     2521 tcaacagctt ggaggaattc agcctcgtgc ccgttacgag ctttcacagt ttcaaacacg
     2581 ctttggatat attctttagc agatgtcata tcgttctcct tttattgtca tattttatta
     2641 cataagac
//
LOCUS       DAVHSH010000098         2592 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000098 DAVHSH010000000
VERSION     DAVHSH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.099"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            78..1661
                     /locus_tag="VVR08_002051"
     CDS             78..1661
                     /locus_tag="VVR08_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6075874.1"
                     /translation="MNQIMKQYKFLYFLIILLSLTSALLMTFFSLQLGRILDSITNSN
                     SGLLFHITICVSLILLWFFISCSYSYLKNQYVKKVIIDLKKGLLLHYLSREFNQIDNR
                     NHSDFLNNITKNSDLIQENLLIPRISLIANLGTLIMSVVAIIYIEWRLALVFLLLSSI
                     TIFLSQIPGKLMTKATNNYSLQNSHYLSKMTNFINGFEQIKLLNIQSWTQEKIQGISL
                     EFEESRKTYQFLKDLASTTGILLSFGSQLSCMVAGIFFVRNNLLTIGLLVASIQLLNG
                     VFAPLQSILYNKNLISSSKSIIDNIQENLYETNHGTFHKTSTIDCDNISTISISQLYY
                     EIENRILFDHFSYEFKKGKRYAIIGASGTGKTTLVKLILNYYPKNLYDGEIKINGKQN
                     IDIPSEELYKDIAFVQKNDFLIEGNILENIKLARNLHLTEKLRKSLGFNEDFLRKNLA
                     QSNKIISEGEKQRIDLARFLVKTYSVYIFDEPTSNLDPIKANEIMDYILSIKDAIVIV
                     ITHDQNPEILEEFDHVITL"
     gene            complement(1671..2534)
                     /locus_tag="VVR08_002052"
     CDS             complement(1671..2534)
                     /locus_tag="VVR08_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6075875.1"
                     /translation="MILGETYRKIREEKGISISSLAGAEISKSQISRFELGETEISVF
                     KLLYLLERIGVTLEEFLLICNHYQPSDFNTLIASVKQAAYNEDTQTLLDMVEKEMELF
                     RGTNSHYHKLNAIFIESIVSGMDKNHQLSRQDASYLTNYLFSVENWGYYETLILGNCC
                     RVLSPDLLFRYTKEALKKGKLYSPIPRNRQSLIQLLLNSLIIMIENDLYEESLFLKQA
                     TKNILADSTDFFEQTILLYLDGYLELKFYHNQKSLLKIKEALKIFELFNKTIYKNYKQ
                     YFEKHIIHLVD"
BASE COUNT          931 a          390 c          363 g          908 t
ORIGIN      
        1 ccaaatgcgg gaagtttgtt tctgattttc atatttggat tataatattc tcatcagagt
       61 tacttaagga gtaagatatg aaccagatta tgaaacaata taaatttcta tatttcttga
      121 ttattttatt aagcttgaca agtgctcttt taatgacatt cttctctctt caattaggaa
      181 gaatacttga tagtataact aattcaaata gtggattact ctttcatatc actatttgtg
      241 taagtttaat tttactgtgg ttctttatct cttgttctta ttcctatctt aaaaatcaat
      301 atgtaaaaaa agttattata gatctaaaaa agggtctctt attacattat ttatcgcgtg
      361 aatttaacca aattgacaac cgtaaccatt cagatttctt aaataatatc accaaaaata
      421 gtgaccttat tcaagaaaat ttattgattc ctagaatctc tctaattgca aatttaggga
      481 cccttatcat gagtgtggtt gccattatct atatagaatg gcgattagca ttagtctttc
      541 ttttattgtc gagtataacg atttttctat ctcaaattcc tggaaagtta atgactaaag
      601 caactaataa ttattcccta caaaatagtc actatttgtc aaaaatgaca aactttatta
      661 atggttttga acaaattaag ttattaaata ttcaaagctg gacccaagaa aaaattcagg
      721 gaatcagttt agaatttgaa gagtccagaa agacatatca attcttaaaa gacttagctt
      781 caactactgg aattttacta agttttggct ctcaactatc ctgtatggtc gctggtatct
      841 tttttgtaag aaataactta ctgactattg gactactagt agcaagtatt caattattaa
      901 acggtgtttt tgctccacta caatctattc tttacaataa aaatttaatc agcagtagca
      961 agtccattat tgataatatc caagaaaatc tatatgagac aaatcatgga actttccata
     1021 aaacaagtac aattgattgt gataacattt cgactatttc tattagccaa ttatattatg
     1081 aaattgaaaa tagaatatta tttgatcatt tttcctatga atttaaaaaa ggcaagcgct
     1141 atgcgattat cggtgcttca ggaactggga aaacaacttt agtaaaatta atactaaatt
     1201 attatccaaa aaatctttat gatggagaaa taaaaatcaa cggaaaacag aatattgata
     1261 ttccctcaga ggagttatat aaagatattg cgtttgtgca aaaaaatgac tttctaattg
     1321 aaggcaatat tctagagaat atcaaattgg ctagaaacct tcatttaact gaaaaattaa
     1381 gaaaatcctt aggttttaat gaagacttcc ttcgtaaaaa cctagctcaa tcaaacaaaa
     1441 tcatttcaga aggagaaaag caacgaattg atttagctag gtttttagtc aaaacatatt
     1501 cagtttatat atttgacgaa cctacaagta accttgatcc aataaaagca aatgaaataa
     1561 tggactacat tctatccatt aaagatgcaa ttgttattgt cattactcat gatcaaaatc
     1621 cagaaatatt ggaagagttt gatcacgtta ttaccttata gataaatggc ctagtctact
     1681 aaatgaatga tgtgtttctc aaagtattgt ttgtaatttt tgtagattgt tttattgaag
     1741 agttcgaaaa tttttaaagc ttctttgatt tttaaaagtg atttttgatt atgatagaat
     1801 ttcagttcca aatatccatc taaatatagc aaaatagttt gttcaaaaaa atctgtggaa
     1861 tccgctaata tattcttcgt agcctgtttt aaaaataaag attcctcata taagtcgttc
     1921 tcaatcatta taatcaaaga attgagaagt agttgaatga gagattgtct atttctaggt
     1981 ataggactat acaacttccc ttttttgagc gcctctttgg tatatctaaa taataaatct
     2041 ggagatagaa cacgacagca atttccaagg atgagcgttt cgtaataacc ccagttttca
     2101 acagaaaata aataatttgt aagataagag gcgtcctgac gactcaattg atgattctta
     2161 tccattcccg aaacaatact ttcaatgaaa atagcattta atttatggta atgagaattt
     2221 gtcccacgaa aaagttccat ttctttctct accatatcta gtaatgtttg agtatcttca
     2281 ttatatgcgg cctgtttaac agaagctatt aaggtattaa aatccgaagg ttgataatga
     2341 ttacagataa gcagaaattc ttctagtgtt actcctattc tttcaagaag atacaataac
     2401 ttaaagacag aaatctctgt ttctcctaat tcaaacctag atatttgaga ttttgaaatt
     2461 tcagcacctg ctaatgaaga aatagaaatc cccttttctt ctcttatttt cctataagtt
     2521 tcacctaaaa tcatacttat ctccatttac cataaacaat cattagaaaa tgtgaccgat
     2581 tatgaaaaaa ta
//
LOCUS       DAVHSH010000099         2194 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.100, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000099 DAVHSH010000000
VERSION     DAVHSH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.100"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(275..1750)
                     /locus_tag="VVR08_002053"
     CDS             complement(275..1750)
                     /locus_tag="VVR08_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU6075876.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINTIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT          647 a          492 c          399 g          656 t
ORIGIN      
        1 ctcgcttttc acctgctttt aaggcctatc ttaagactaa gttagaataa ggaaaacatt
       61 acaatgtagc catcatccac cttgcaaaaa aacttatccg aaccctgttt tatatcctaa
      121 aaaagagctg ccatttgacg aacaaaaagt gatgtaattt ctgaaattaa cacaggatta
      181 cctttgaaaa aatggacttt ttcaagagct ttttgccatg ctctaaaatc atcgccaaat
      241 catcaaattg aaataagaaa tagtttagat aaaactattg acttttctta tagtttgtct
      301 ttctcttaat gacgttgatg tgattgacct ctggatcttc cgtcccttgg agggagcaac
      361 cacgttcctt ggcaaattgg atatagtcga caatttctcg tgtgatgcgt tcgccaggag
      421 ccaagatagg gattcctgga gggtaacaca tgacaaattc cccacagacc tgtccaacag
      481 attcgtccaa ggtcaaactt tttctctctg aatagaaggc ttcttgcgga gacagcacta
      541 actcgggctg aatatattct cctgctatca aatcttttcc atctcttgaa tagagtctct
      601 taatatcagc cagagcacca accaagcgct cgatgtcttg gatgcggtcg ccgatggaaa
      661 tataggccaa gatattgccg atatcaccaa actcgatctg aatgtcgtat tcgtctcgca
      721 agaggtcata aacctcgata cctgttaagc ctattccctg agtgtaaact gacaacttgg
      781 ttacatcaaa atcacagacc gacacaccat ctattaactc ttttgagtaa gcatagtaac
      841 cgccaatggt attgatttca tgacgagcgt actcggatag ctcaatgact tcctcaaacg
      901 actctttacc acgaagggcc aagttgcgac gtgaaatatc caaactagcc atcaataagt
      961 aagaggcaga tgtagactgg gtcaggttta taatctgacg aacgtactcg ggattcatct
     1021 gctccccgat taaaagaagc gaactttgtg tcaaactccc accagactta tgcatggaaa
     1081 ctgctgccat atcagctcct gcatccatag cagaaattgg aagtttacca gtgaaatgca
     1141 aatgcgctcc atgggcttca tctactaaaa ccatcatgcc agcttcatga gccatttctg
     1201 tcaacccctt taggtctgaa cagatgccgt agtaagtagg attgttgatt aggatagcct
     1261 tagcatctgg atggtccttt atggcctgtg ctactcggtc attttcaaga cctaaagcga
     1321 taccaatctt aggatctaca ctcatctcga tatagatggg aatggcacca catagaacca
     1381 acgcattgat agcagattta tggacatttc gtggcagaat aatcttatct cctgccttgc
     1441 aggttgccag aatcatagtc tgcaccgatg aagttgttcc accaatcatt agaaaggcat
     1501 ggctagctcc aaaagcatct gcagccagct cctctgcatc acgaataatc gaaataggat
     1561 ggcctaaatt atccaagggt ttcatcgaat tgacatcaat gcctacacat ttttctccta
     1621 agagttcgac aagttctgga tttccccgtc cacgcttgtg acctggaaca tcaaagggaa
     1681 caatcctttt cttgcgtaac ttcaccaagg cctcataaat tggggcttgg ttttgatcta
     1741 actctttcaa aacatactcc tttcaatatt tttaggacct tatgaaaact aaggaactaa
     1801 aggttgactc atgaaaaaag agcaggtttt cacctgctct gcaatcttct gacgtgttta
     1861 ttttggtttc tgttgagtat gtctgttccc gatgtttcct aactctctag tagcaaatat
     1921 tacgtacttt attgatcgtt tcacaagatg acgtgtgctt tcaccacact aaaaatttat
     1981 gaattagaac aagtgtccta acatcaactt ataaaagtag gcttttaacc ctatcaataa
     2041 tgtggctttt caaccacgct tcggcattca accctgcctg tccgtaggca ttttttactc
     2101 gggtttatat ttgctagaaa acatcatctc attttctaag ctttattact atatcatgtt
     2161 tttaagaact tgtaaagtat tttttgataa aaaa
//
LOCUS       DAVHSH010000100         2140 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000100 DAVHSH010000000
VERSION     DAVHSH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.101"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(<1..461)
                     /locus_tag="VVR08_002054"
     CDS             complement(<1..461)
                     /locus_tag="VVR08_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6075877.1"
                     /translation="MEIEECKKISILDVASRLGISFKQVSSSVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPFQKETVQEKRERPFYYPLKRI
                     EDSHCSLARYYLTECRGISEEIVQKMIQQGLIVQASWKTNETVEPVIVFKS"
     gene            complement(471..1112)
                     /locus_tag="VVR08_002055"
     CDS             complement(471..1112)
                     /locus_tag="VVR08_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6075878.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILLSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPSLPNTTTK"
BASE COUNT          718 a          359 c          326 g          737 t
ORIGIN      
        1 aagcttttaa aaacaataac aggttcaact gtttcatttg ttttccaact agcttgtact
       61 atcaaacctt gttgaatcat cttttgtacg atttcttctg aaattcctct acattctgtt
      121 aagtaatatc tggccagact acagtgagaa tcttctattc tctttaaagg ataataaaat
      181 ggtctctctc ttttttcttg aacagtttct ttttgaaaag gttcttcaga aagaaaggct
      241 agagcttctt taaaggaaat tcccttaaca agtcgaacaa aatcaatgac atcaccttga
      301 atatctcttg aaaaccattt aaaagtattg gtagttgaaa aaatccgaaa tgaatcgtgt
      361 tcaggatgtt catagacact gctcgaaact tgtttaaagg agatacctaa acgacttgct
      421 acatcaagaa ttgaaatttt cttacattct tctatttcca tgcaatatca tcattttgtc
      481 gtagtatttg gcagtgatgg aacagatgag gattcttcta aagttttagg agttgcctta
      541 tctaaatcat ctaacccaga tttccaaacc tgtacttggt tgaccaataa cttaccaggt
      601 agtttagaat aggataactt aactgttctt gtttctgtct gattcgtctt tgattggttg
      661 gcattcttta aatcagatac ataggttaca ttataagaga ccatggcaat agcttgattc
      721 gtagtctgat tgacaaagat atcagctttt tcgaaatgat aatctaaaat ataatcctta
      781 tacacttggt tcatggcatc attttgactt gacaattctt gagaataagc cgattcagtc
      841 atataaggtt gaatacgtgt attattttct ccgagctttt ctttcgtata gtactgtgtc
      901 aaaaattctt ttacagtatc tgataacaaa atacttgctt tatcttctgc ttgtttgtcc
      961 tctacaagtt tagctgcagc caattcaatc tctttacgac tttgtttagc agtagaatgt
     1021 tgaccagcag tatatcccat catgagaata aagctagttg cagccactgc tccaacacta
     1081 attaaggctt tagttttgac tttatttaac atcttagacc ttctttctat aaaaactagg
     1141 tcaagaataa caaaaagaac ttgtaagttt tatcacatca caacgaaagg taattcctac
     1201 atttcaggca caaaatcgta cagttcagag aaaaaaaaaa ctagctgtct ttgacagtat
     1261 aatagactta ttggaaaaaa ataaaatgca tactgtacta tgctatacta tagttaagaa
     1321 aactatttac aaaagatcat gcaactaact tctgagaact ttaaattatt tattagtgta
     1381 aaaaaggaca ccttcccaac gaagatatcc tgtctaaata aagcttataa aaccaaacac
     1441 tataaaggag gacgttcaaa aacgctaagt ctataaaaac agttgatgct aaacttgcgt
     1501 tatttattct attgaacaac tctacgtctc ctagcttttg attttggtct tggattagcg
     1561 acagtcaccg aacgataata ttggtagaag atactcttcg ttcttcaggt atatttgcct
     1621 tagacaactt aaaagcagca agtgtcacta tagctattga tgtcatagaa agtcctattt
     1681 caatgtccta aagaaaccaa agtaagaatt atcctggaaa aagatataca ccataaagac
     1741 acaatcatac tcgatttaac gacacttcgt gcctgtcaat tttttttttg agatggtcat
     1801 acacatgatt ttactctttt taaagaaagt ataggtcaag tttgtcagag caatcacttg
     1861 tttttgttat ttagatactg tgaatattca tcagatatct ttattcctat aaaaagttca
     1921 aaaaggcatg aattgactgt agaggataag aaatttaata gagatagtta taatacgtat
     1981 taaaattgag cgtttaaatg ctaagtttaa aacttttcaa tttgtggaat catcaactat
     2041 gagttaaaat aatttacgaa cagaggctgt ccaaaaaact tgatatcata cgttttattg
     2101 tggaaatatt cattttttct cctgaaattg agttttttcc
//
LOCUS       DAVHSH010000101         1813 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000101 DAVHSH010000000
VERSION     DAVHSH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.102"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..1641
                     /locus_tag="VVR08_002056"
     rRNA            <1..1641
                     /locus_tag="VVR08_002056"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            1718..>1813
                     /gene="rrf"
                     /locus_tag="VVR08_002057"
     rRNA            1718..>1813
                     /gene="rrf"
                     /locus_tag="VVR08_002057"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          501 a          373 c          533 g          406 t
ORIGIN      
        1 tggaacgcat agaagtgaga atgccggtat gagtagcgaa agacaggtga gaatcctgtc
       61 caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc ctgggttagt cgggacctaa
      121 ggagagaccg aaaggtgtat ccgatggaca acaggttgat attcctgtac tagagtatgt
      181 agtgatggag ggacgcagta ggctaactaa agcagacgat tggaagagtc tgtctaagca
      241 gtgaggtgtg aattgagtca aatgcttaat tctataacat tgagctgtga tggggagcga
      301 agtttagtag cgaagttagt gacgtcacac tgccaagaaa agcttctagc gtttaaacat
      361 actctacccg taccgcaaac cgacacaggt agtcgaggcg agtagcctca ggtgagcgag
      421 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      481 cttaaagtca gccgcagtga ataggcccaa gcaactgttt atcaaaaaca cagctctctg
      541 ctaaatcgta agatgatgta tagggggtga cgcctgcccg gtgctggaag gttaagagga
      601 gtgcttagcg taagcgaagg tatgaattga agccccagta aacggcggcc gtaactataa
      661 cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acccgcacga aaggcgtaat
      721 gatttgggca ctgtctcaac gagagactcg gtgaaatttt agtacctgtg aagatgcagg
      781 ttacccgcga caggacggaa agaccccatg gagctttact gcagtttgat attgagtgtc
      841 tgtaccacat gtacaggata ggtaggagtc taagagatcg ggacgccagt ttcgaaggag
      901 acgctgttgg gatactaccc ttgtgttatg gccactctaa cccagatagg tgatccctat
      961 cggagacagt gtctgacggg cagtttgact ggggcggtcg cctcctaaaa ggtaacggag
     1021 gcgcccaaag gttccctcag aatggttgga aatcattcgc agagtgtaaa ggtataaggg
     1081 agcttgactg cgagagctac aactcgagca gggacgaaag tcgggcttag tgatccggtg
     1141 gttccgtatg gaagggccat cgctcaacgg ataaaagcta ccctggggat aacaggctta
     1201 tctcccccaa gagttcacat cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat
     1261 cctggggctg tagtcggtcc caagggttgg gctgttcgcc cattaaagcg gcacgcgagc
     1321 tgggttcaga acgtcgtgag acagttcggt ccctatccgt cgcgggcgta ggaaatttga
     1381 gaggatctgc tcctagtacg agaggaccag agtggactta ccgctggtgt accagttgtc
     1441 ttgccaaagg catcgctggg tagctatgta gggaagggat aaacgctgaa agcatctaag
     1501 tgtgaaaccc acctcaagat gagatttccc atgattatat atcagtaaga gccctgagag
     1561 atgatcaggt agataggtta gaagtggaag tgtggcgaca catgtagcgg actaatacta
     1621 atagctcgag gacttatcca aagtaactga gaatatgaaa gcgaacggtt ttcttaaatt
     1681 gaatagatat tcaattttga gtaggtatta ctcagagtta agtgacgata gcctaggaga
     1741 tacacctgta cccatgccga acacagaagt taagccctag aacgccggaa gtagttgggg
     1801 gttgccccct gtg
//
LOCUS       DAVHSH010000102         1685 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000102 DAVHSH010000000
VERSION     DAVHSH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.103"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            95..898
                     /locus_tag="VVR08_002058"
     CDS             95..898
                     /locus_tag="VVR08_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU6075879.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQARGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNARTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1014..>1685)
                     /locus_tag="VVR08_002059"
     CDS             complement(1014..>1685)
                     /locus_tag="VVR08_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6075880.1"
                     /translation="RIYLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDV
                     GKKAENLIQGQFEGSKTMEQCYTDVTEFTIPVSTQKLYLSPVLDGFNSEIIAYNLSTS
                     PNLEQVQTMLEQAFTEKHYENTILYSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPD
                     NGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYR
                     TKSFG"
BASE COUNT          498 a          304 c          318 g          565 t
ORIGIN      
        1 aacctattgt gaggactttt tatagtttaa gccagtttcc aaccaatttc gtgatttact
       61 ggtaatgaag aaaaacaatt gaaaggatat ttctatgcaa ccaacttaca acattgacaa
      121 tccaaacttg tcttatgaag ctaagcgtga tttatggcgg ataggttttg gtctgcagaa
      181 agttgacaat ctagtgccat cagcttatat ggaatctttg gctgagaaac aggctcgggg
      241 tgaactgact tatgagcagg tttatgagga tgcaacggct tatcaccata ctattgatgc
      301 aagtacggag gaggcagact tggtttctct acgcattgta gaactattgt ctcgaagagg
      361 ctttagcttc agtcctgcga ccttacttgc tattcataag gagttgtttc aagatatatt
      421 tgaaccctcg attccggtag gtcaatttcg tcagactaat atcacaaaga atgaacctgt
      481 tttgaatggt gaaagtgttg tgtactctga ttactccatg attcaaatga cattggatta
      541 tgattttaat caggaaaaac aagttgcata tgcgacacta acccaggcgg atatggttaa
      601 aaaaatccag cattttattt caggaatctg gcagattcat ccatttcgcg aaggaaacgc
      661 tcggacagta acggtctttt tgattcagta tcttcgtgag tttggttttg atattgataa
      721 tataccattt cagcaacatt ccaagtattt tcgtgatgcc ttggtattag ataatgcaaa
      781 gattttacag cgacgtcctg agtttttaac agcttttttt gaaaatctct tgctcggtgg
      841 tcaaaatgat ttgtcttcag aaaaaatgta tctagattta gacctcgatt tttcataatc
      901 caaatactga gtaaacattg aattttagga aaaaatgaag taaacattcc cacaataaaa
      961 cgcatagtat caagtgttaa aatgtactgc cccccaaaag ttagacaatt aatttatccg
     1021 aaggatttag ttctgtattg cacagggcta agtcctttta gttttacctt aattctctta
     1081 ttgttgtaat aatcaatata gtctacaatg gcttgttcca attgcttaag cgactgaaac
     1141 gacttctcat aaccgtaaaa catttccgat ttcagaatcc caaagaagga ctccatcata
     1201 ccattgtctg ggctgttacc cttacgtgac atggatgctt gaattccctt accctcaaga
     1261 aactgatgat aagaatcgtg ttgatattgc cagccttggt cactatagag aatcgtattc
     1321 tcgtagtgct tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt
     1381 gaagttgaaa gattataggc gataatttcg ctgttaaaac catctaaaac tggtgataag
     1441 taaagctttt gagtacttac tggaatggta aattcagtca catctgtgta gcactgttcc
     1501 attgttttag agccttcaaa ttggccttga atgagattct ctgctttctt accaacgtct
     1561 cctttatgag aagaatattt tcgtttctgt cgcattttag cttgtaaatt gagtactttc
     1621 atcaagcctt gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa
     1681 atccg
//
LOCUS       DAVHSH010000103         1643 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000103 DAVHSH010000000
VERSION     DAVHSH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.104"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            127..1473
                     /locus_tag="VVR08_002060"
     CDS             127..1473
                     /locus_tag="VVR08_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU6075881.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDKETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQCYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          481 a          355 c          324 g          483 t
ORIGIN      
        1 ccttgcctta gcttagatcc tggatggttt cttttttcac ccaatgggtg ttttttacta
       61 gacaaaaaag agtttcccct ttatggtata agtgtagaaa aaaacacaaa aagaaaggaa
      121 actcacatga acagtttacc aaatcatcac ttccaaaaca agtcttttta ccaactatct
      181 ttcgatggag gtcatttaac ccagtatggt ggtcttatct tttttcagga acttttttcc
      241 cagttgaaac taaaagagcg gatttctaag tatttagtaa cgaatgacca acgccgctac
      301 tgtcgttatt cggattcaga tatccttgtc cagttcctct ttcaactgtt aacaggctat
      361 ggaacggact atgcttgtaa agaattgtca gctgatgcct actttccaaa attgttggaa
      421 ggagggcagc ttgcttcaca gccaacctta tcccgttttc tttccagaac tgacaaggaa
      481 acagtccata gtttgcgatg cctcaacctt gaattggtcg aattcttttt acagtttcac
      541 cagctaaacc aactcattgt agatatcgat tctacccatt tcacaactta tggcaagcaa
      601 gaaggtgttg cttataacgc ccactatcgt gctcatggct atcatcctct ttatgctttc
      661 gaggggaaga caggttattg tttcaatgcc cagcttcgtc ctggtaatcg ttattgttct
      721 gaagaggcag acagctttat cacacctgtt ttagaacggt ttaatcaact tctctttcga
      781 atggatagtg gctttgcgac cccaaaatta tacgatttaa ttgaaaaaac agggcaatgc
      841 tacctcataa aactcaagaa aaatactgtt ctgagccgtc ttggagacct ttccctccct
      901 tgcccacagg atgaggactt aaccatcttg ccccactccg cctactcaga aactctctat
      961 caagcaggat cttggtcgca caagcgtcgt gtctgccagt tctctgaacg aaaagaagga
     1021 aacttgttct acgatgttat ttctctcgtt acaaatatga cgagtggaac aagccaagac
     1081 cagtttcagc tttatcgtgg acgtggtcaa gccgagaatt tcatcaagga gatgaaggag
     1141 ggattttttg gcgataaaac ggatagttca accttaatca aaaacgaagt tcgtatgatg
     1201 atgagctgta tcgcctacaa tctctatctt tttctcaaac atctagctgg aggtgacttc
     1261 caaactttaa caatcaaacg cttccgccat ctttttcttc acgtggtagg aaaatgtgtt
     1321 cgaacaggac gcaagcagct cctcaaattg tctagtctct atgcctattc cgaattgttt
     1381 tcagcacttt attctaggat tagaaaagtc aacctgaatc ttcctgttcc ttatgaacca
     1441 cctagaagaa aagcatcgtt aatgatgcat taaagaacag tcgagatgaa aaaatcgtgt
     1501 gacgcaccaa gggaggagtc tgcccttttg aggaaatcta gcgaggaaaa acgatactgg
     1561 aacagcagaa agtaaaactg acctcatgag gaggaagaaa gtggctcatg aggtcagggg
     1621 ttttgtaagt tacatctagt tga
//
LOCUS       DAVHSH010000104         1574 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000104 DAVHSH010000000
VERSION     DAVHSH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.105"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            25..>1574
                     /locus_tag="VVR08_002061"
     CDS             25..>1574
                     /locus_tag="VVR08_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU6075882.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCV"
BASE COUNT          598 a          178 c          280 g          518 t
ORIGIN      
        1 agctaatgat aggatagtta aaatatggaa gaaaattata atttatctat aactcaaata
       61 aagaattcta ttaaagaaaa ttccttagtt ttgtttgttg gtgcaggaat atcagctaat
      121 tctaatctac caacttgggg agaattgatt caatcattaa aaaaagaatt gaacatacca
      181 gaagaaagaa cagatagtcc actgagaatt gctcagtatt attatgatac ttttgggaaa
      241 aatcagtaca caaagaagat agaagaaatt ttctttaaga agggattgag taaaccaaat
      301 gagttacata aattaataga aaaaattgca ccaaaacata ttattacgac aaactatgat
      361 tcacttctgg agagtcaatt tgaaagtggc ttgttaaagt acaatgtagt cgctgaggat
      421 aaagacatcc cttatacgag ttcggaaaga tacttgatta aaatgcatgg tgacttcagt
      481 aagaaaaata ttgttttgaa agaagatgat tatttagact atcatttgaa cttcccaatg
      541 atttctactt taatccagtc attgataatg aatcatactc tattgtttgt ggggtattct
      601 ctaagtgatt cgacttttaa ttcaattttt agaatgattc aaaatacatt taaattggat
      661 gctaaaaatg cttattttta tactcccgag gaaccgtcta tgatcattcg agagtattat
      721 aagaagcaag gaattttcat tatctctaat gaagagaatc taggtcagga gacatcagaa
      781 aaacagaaca aattgtattg caggacaaaa gattttttag aggttctatc agaaaaccga
      841 agtcaagatg taaataatgc tgatgattta tggaatcaac tggctttttt agatagactt
      901 agttttattg atgcgaaaga tttttctaga tattctgatt taaagaaaag ggctttaaac
      961 tgggatgatg agtattgctg gtttggaaat gatcaattaa gatttgaaat tgatggtcat
     1021 gaagaattac gaattatggt atctaaaaaa tctttattaa atcgctttct agatatggag
     1081 attggtgagc ctagggattt aaaggggaat cgattcttaa gtaaggcttt taagttgtat
     1141 gaagaaaaac aatattcttt agcaaaagca aaatttagag aactagctaa tatagcattt
     1201 cgtcagaaag actattttaa tttcttagtt tgtgaattta attttcagca aattcaaata
     1261 attgatagat acgaaaaaac acctagttat gcagagccac tttatgatgg agaattaagc
     1321 gaattaacag aacaaattct taactcggtt acaggagatg agaaaaagat tatagaattt
     1381 tttagagatt caatccttaa cttcaatttt ttatatagaa aattagaaac tattaatgaa
     1441 ttatttgatg aaattcgtga agagcatgaa agctatagaa gaggaggatg gtctgctaat
     1501 aatcatctat ttaatgcgga gtttacagta aaaaatcttt ataacttttt aaaattaaat
     1561 tgtttatgtg ttga
//
LOCUS       DAVHSH010000105         1512 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000105 DAVHSH010000000
VERSION     DAVHSH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.106"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            11..292
                     /locus_tag="VVR08_002062"
     CDS             11..292
                     /locus_tag="VVR08_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU6075883.1"
                     /translation="MEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAVFESI
                     FEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            602..>1512
                     /locus_tag="VVR08_002063"
     CDS             602..>1512
                     /locus_tag="VVR08_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU6075884.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVID"
BASE COUNT          714 a          184 c          269 g          345 t
ORIGIN      
        1 tgaagaacag attgaaaaga aagaagaaag cattaagcaa ttacaaaatc aaaaaagaca
       61 gttgaagaaa aaacttaatg aacaagaaag aaaagcaaga aacaaaagac ttatagaaaa
      121 aggtgcagtg tttgaaagta tttttgaaga aagtattgat ttaacaaaag atgaatttta
      181 taagttaata aaaacgttaa atgatgaaga aataagatta aacataatgg aaattttaga
      241 agaaagaata gatgataatg tagaaaaatc atctaaagat gaaataacat aattgtccct
      301 tggttacaag ggcgcaatta tacaccctaa agggtgcttg cgtcctgcgg agtcaaaccc
      361 ttgcagggag caacaaccat tcgcttttta aaagtcaagg gtaaataaac tcgctaaggc
      421 tcgcccttga cttttaaaat ttgaaatgaa agtaacaatt aagccgacat actgaaacaa
      481 caaaaattaa ttcagtagtc ggcttttttt attctatcat ttcaaaacgc tcattcacaa
      541 agaggatata aaaaaactat taagcctcca cctaaaacaa caaagaaagg aagtgataaa
      601 aatggcagac agttttcatt tttcagtaaa cataatatca agaggaaaag gcaaaagtgc
      661 agtagcaagt gcagcatata taagtggaga aaaaataaaa aatgaatggg acggagtaac
      721 ccatgactac acaagaaaag aaaaaatatt agtaaaaaat ataatattgc ctgatcatat
      781 accaaaagaa tttaatgata ggtctacctt atggaataaa gtagaaatgg cagaaaaaaa
      841 ttctaatgca caactagcaa gacaattcat aataggacta ccaaaagagt tatctttaag
      901 tgaaaataaa aacctggttg aaagatatat aaaagaaaat ttaacatcac aaggaatgat
      961 agtagattat gcaattcatg atgagagtca agataaaaat ggaaatatcc attgtcatat
     1021 aatgaccata atgcgaccaa taaacgaaaa aggagagttc ttagccaagt caaaaaaaga
     1081 atatatccta gatgaaaaag gagaaaaagt attaaacaaa aatggaaaac caaagacaag
     1141 aaaagtagaa ctaacaacct ggaacgatac aggcaatgta gaaaaatgga gagaaaattt
     1201 ttcagatctt tgtaacaaat atttagaaag agcaggagca gaaaaaagag tagaccatag
     1261 gagttttaaa agacaaaatt cagattatct accgacaatc catttaggat cagcagcaag
     1321 tgcaatggaa agaaagggaa tagaaactga caagggaaac tataatagag aaataagaaa
     1381 atataatcaa cttgtaaaaa caataaaaga agagataaaa acattaaagg gttggatagg
     1441 aaatttatta gataacttat ctactgctta tgaaaaattt aaggatatag aaagagataa
     1501 ggtaatagac aa
//
LOCUS       DAVHSH010000106         1512 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.107, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000106 DAVHSH010000000
VERSION     DAVHSH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.107"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..710
                     /locus_tag="VVR08_002064"
     CDS             <1..710
                     /locus_tag="VVR08_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075885.1"
                     /translation="PFFIENSKVGNYFKIFVKNGGQFIPIIDCTEFKIQSKKYFEINI
                     NKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENIRVVSLLDCLIQLS
                     SKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYIYFLMKEIDNITKK
                     YPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRYFTDIPFIDTSLSI
                     EEFDKIVSKILKIKVGG"
     gene            713..1384
                     /locus_tag="VVR08_002065"
     CDS             713..1384
                     /locus_tag="VVR08_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075886.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDAELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            1386..>1512
                     /locus_tag="VVR08_002066"
     CDS             1386..>1512
                     /locus_tag="VVR08_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HEU6075887.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVI"
BASE COUNT          586 a          168 c          229 g          529 t
ORIGIN      
        1 ttccattttt tattgaaaac tcaaaagttg gaaattattt taaaattttt gtgaaaaatg
       61 gaggacagtt tattcctata attgactgta cggaatttaa gattcagtct aagaaatatt
      121 ttgagataaa tattaataaa ttctacctga aacttttgga ttactttctt catggagaga
      181 ttccagaaaa atttaaattt tttggaaata cctctaattt caatatagaa agcttgtttc
      241 tagaatttat tgatagccaa gaaaatattc gagtagtttc cttgttggat tgtcttattc
      301 aattatcctc taaaaatatt gaaatttcag gaaattataa agggcacaca gtgaaaaaaa
      361 tactaaaaaa attcgcttta tactcagtaa ttaccaaact tgatataacg aaagtaaatc
      421 atttattgag aaatgattat atctactttt taatgaagga aattgacaat attactaaaa
      481 aatatccaaa gttaattcaa aagtacccta gagatatctt gagtgatagg tatggaataa
      541 caaatgaagt atatagatac ttaatcggag agaatttaca tataaaaatt aatcataaat
      601 tagatgaggt tagatatttt acagatattc catttattga tacttcactt tctattgaag
      661 agtttgacaa aatagtttct aaaatattaa aaattaaagt gggagggtaa ctatgataag
      721 attaccaaat aaatttaaag gtaataatat aactctagaa gttaaactaa ataaagcagt
      781 tgatgctagt gtattatacc cagatgttaa gtctctagat caagaattgt atcgacaact
      841 acaatcagta gaatcattct atcttacctt ttctgatatg tattcagaaa ttaatgaaaa
      901 taatgaaatc ttatatacag aaataatctt taagatacct ctttgtattg gagaagatta
      961 ttttaatttt ccggttgtat catatgtttc aaatccctat tcgttaataa gaggatttta
     1021 tctaggtttt cataaggaat tggactgtaa ctatgtattt gatgatgcag agcttcattt
     1081 ttttagggaa gggatttgtg aatttaactt cgaatttaaa aatcaaaatt caatcattac
     1141 agcagaatta ccaagggagt ataactatcc cttgatcttg tttaataatt ccaatctggt
     1201 taatcaatat ggaaaatata ctttgttaga catagacaaa tataaattag agtctagaaa
     1261 gatttttgaa tttccagaaa tttctatcgg taactttctt ggaagtgaag caaaatcaaa
     1321 tagggtaatt tttagccaag ataaatttca aattaatggt ataaagaata tggaggtaaa
     1381 ttagcatgaa atcattatta ataacaggtg gagcaggata cataggatca catacagttt
     1441 tggacttgtt agataataat tatgaagtaa caatcattga tgatttgagt aactctaaga
     1501 aaaaagttat tg
//
LOCUS       DAVHSH010000107         1456 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000107 DAVHSH010000000
VERSION     DAVHSH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.108"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            1..427
                     /locus_tag="VVR08_002067"
                     /pseudo
     CDS             1..427
                     /locus_tag="VVR08_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1165..1425)
                     /locus_tag="VVR08_002068"
     CDS             complement(1165..1425)
                     /locus_tag="VVR08_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075888.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          488 a          273 c          257 g          438 t
ORIGIN      
        1 aattagcgaa ttattctggt aaaaagaaat gccacgctat gaaggctcaa gcgattgtca
       61 caagtcgagg gagattgttt ctttggatat cactgtgaac tattgtcatg atatgaagtt
      121 gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttggctg acagtggtta
      181 tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca gcaaactcaa
      241 gccgctaaca gctgaagata aagcctataa ccatgcgcta tctaaggaga gaagcaaggt
      301 tgagaacatc tttgccaaag tagaaacgtt taaaatgttt tcaacaacct atcgaaatca
      361 tcgtaaacgc tttggattac gaatgaattt gattgctggt attatcaatc atgaactagg
      421 attctagttt tgcaggaagt ctattatata tgcacagaca tatgaaatct ttttgagata
      481 gcagttatga tatatttatc cattcacaac atcttctgta ccaatactac aatattggta
      541 cattttgatt acacaatcgt ttcaaaaaat atgatggaag cctgagtatt ttatagtaac
      601 tcccttccta tcaactagat caaccagttg agtgttgaat gttgaaacac cctagcctca
      661 gcaaaggact atgagcagca tttcctagcc aataggacgc tccaaatcac ctattctaaa
      721 tccatcacta gcttggtcag taagatacag actgcaaggc aagactgacg tggttgatga
      781 gattttggaa gagtattaca atcatagatt caccagtaga cttgaccgca gatttaacta
      841 tagtagattg aaactagaat agtacacttc tgcttctaaa acattgttag aaatcgattt
      901 gactgtcctg atcaatttgt cctgttctcg tttcattcta ctatactaaa aaaccacctg
      961 aaacaaatca agtgactaga ggataaaaac gaagactggg caaaaagttt tgaaaagcaa
     1021 aaaacgcata atatcaggtc ttgaaaaacc ttgatactat acgtttgatt gtgggaagat
     1081 tgacttcatt ttctcctgaa attgaagttt tttctagttt ccagatatag acgaattcaa
     1141 tatagccatc tcgctacaat tattttaacc atcgagaaaa tttttcagaa tttcaaaaat
     1201 ttcattttga tccaatgaaa tgtcattatt ttgaagaata gttgacttca caggctctaa
     1261 ttctatcaca aagcggtgca tgtctgcttt taccgcacta cttgatgtta tagccgataa
     1321 cttttcatct cctagcaagg aagctgtcaa acgggtaagg tcattcaaat gctttttaat
     1381 ggacttactt aaaccttgag cacctgtggc agagcgctcc ctcatatcca gccaagcttt
     1441 agccttaaaa ataatt
//
LOCUS       DAVHSH010000108         1318 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000108 DAVHSH010000000
VERSION     DAVHSH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.109"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(72..452)
                     /locus_tag="VVR08_002069"
     CDS             complement(72..452)
                     /locus_tag="VVR08_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6075889.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(445..768)
                     /locus_tag="VVR08_002070"
     CDS             complement(445..768)
                     /locus_tag="VVR08_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075890.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            complement(782..1030)
                     /locus_tag="VVR08_002071"
                     /pseudo
     CDS             complement(782..1030)
                     /locus_tag="VVR08_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(1027..1200)
                     /locus_tag="VVR08_002072"
     CDS             complement(1027..1200)
                     /locus_tag="VVR08_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075891.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQS"
BASE COUNT          426 a          258 c          204 g          430 t
ORIGIN      
        1 cagctgatat ttctttcagc caaaataatg gacaagttct cccaaaatcg ttcagccata
       61 ttgcttctcc tttagttaga taaataatgt gtttgcgcca tgtaaatcaa ttgtttcgta
      121 tctcttggca atagagctct agcctcttcc aaattcagac ttggataaac tcgcttattt
      181 gaaaccgcaa gaggaagtct gatggttagt tcaggatttt ttaaaattat ctcaacgaaa
      241 tccgttaatc ttagattgtc acggttctta aatcgtaata aattgggaga taaaaactca
      301 aaacaatctg aagaatagct catcatctca attaatttgt cctttgtcat ttcagaaact
      361 gaatgacaag atacctctat gccatagttt tggaagaaat ctaaaagaag ttgatttctt
      421 tgtctatttt tacttagata gagatcaatc atgggagacc tcccaaagat tcggttccat
      481 ttgatattct gagacgatta aggaatctaa taaatttgcg aagttaatcg gtttcttgtc
      541 ttcatcataa gcttttacag ttacttgggt tgtaagtatt ccctcttttc cctcggctcg
      601 atagccttgt ccatataaaa caaaaacgag attttgatga tcatctacaa aggcatcaac
      661 cccattcttt atgtcttgac tttcaaggaa ttccataacg ttttgaagat aggattcgta
      721 aaatagtggg taattatgtt ttttatggta atcatctaaa aatgtcacct caaactcaca
      781 tggagagtaa ttttgacttt gaacagccta aaagtgccat caaatttgaa ttggaataaa
      841 tcaaataaat agccccatcc tcatcaatcc aagctttgct caaagacaac tccaaccgat
      901 cttttaaaac tgagtaaacc accttaacct ccagtttcat attcttatac cgttcactct
      961 caaataaaag tttggggagc ttataataac gctctgatgt ctgatattga ctagcggtaa
     1021 tacgcttcat gattgtccct ccaagactaa aattccaaca tttccaaatt catcaaatcg
     1081 gattaaacct acttgttcca tttcatcaac taactgagtt gcttttacaa tatcaactcc
     1141 catgatagtc atgagatgac tcttcacgaa ttgacgtgat gactgtcctt ccttttgcat
     1201 aattacctcc gaaacacaaa aaaaggggta gacaatctag tgtctacctc cgaaaattta
     1261 ttaaaaagaa aaaccctgcc aaagaatttt tggtagggtt tttggtagga aactaaat
//
LOCUS       DAVHSH010000109         1284 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.110, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000109 DAVHSH010000000
VERSION     DAVHSH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.110"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            100..579
                     /locus_tag="VVR08_002073"
     CDS             100..579
                     /locus_tag="VVR08_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6075892.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            673..744
                     /locus_tag="VVR08_002074"
     tRNA            673..744
                     /locus_tag="VVR08_002074"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:706..708,aa:Glu,seq:ttc)
     gene            996..>1284
                     /locus_tag="VVR08_002075"
     rRNA            996..>1284
                     /locus_tag="VVR08_002075"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          456 a          195 c          314 g          319 t
ORIGIN      
        1 tcttttttgt gcagtttagg agctaaaggg aacagaatgg agaaaatgga acaaatgtgt
       61 tttctaatct gttagactgt atctagaaag gggaaaatta tgattaaaga attgtatgaa
      121 gaagtccaag ggactgtgta taagtgtaga aatgaatatt accttcattt atgggaattg
      181 tcggattggg accaagaagg catgctctgc ttacatgaat tgattagtag agaagaagga
      241 ctggcagacg atattccacg tttaaggaaa tatttcaaaa ccaagtttcg aaatcgaatt
      301 ttagactata tccgtaagca ggaaagtcag aagcgtagat acgataaaga accctatgaa
      361 gaagtgggag agatcagtca tcgtataagt gagggaggtc tctggctaga tgattattat
      421 ctctttcatg aaacactaag agattataga aacaaacaaa gtaaagagaa acaagaagaa
      481 ctagaacgcg tcttaagcaa tgaacgattt cgagggcgtc aaagagtatt aagagactta
      541 cgcattgtgt ttaaggagtt tactatccgt acccactagt aagtcatgca aaaaaaatga
      601 aaaaaattag aaaaagtagt tgacaaagtt tgaaaagact gtataatagt aagagttgaa
      661 aataacaact caggtccgtt ggtcaagggg ttaagacacc gccttttcac ggcggtaaca
      721 cgggttcgaa tcccgtacgg actatggtat gttgcgtcag gaccacttga tgaaaaaaag
      781 tttaaaaaaa cttaaaaatc ttcaaaaaag tgttgacaag tgaaagtggc tgtgatatac
      841 taatatagtt gtcgcttgag agaagcaagt gacaaagacc tttgaaaact gaacaagacg
      901 aaccaatgtg cagggcgcta caacataagt tgtagtactg aacaatgaaa aaacaataaa
      961 tctgtcagtg acagaaatga gtgagaactc aaacttttaa tgagagtttg atcctggctc
     1021 aggacgaacg ctggcggcgt gcctaataca tgcaagtaga acgctgaagg agaagcttgc
     1081 ttctctggat gagttgcgaa cgggtgagta acgcgtaggt aacctgcctg gtagcggggg
     1141 ataactattg gaaacgatag ctaataccgc ataagagtgg atgttgcatg acatttgctt
     1201 aaaaggtgca cttgcatcac taccagatgg acctgcgttg tattagctag ttggtggggt
     1261 aacggctcac caaggcgacg atac
//
LOCUS       DAVHSH010000110         1056 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.111, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000110 DAVHSH010000000
VERSION     DAVHSH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.111"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..559
                     /locus_tag="VVR08_002076"
     CDS             <1..559
                     /locus_tag="VVR08_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6075893.1"
                     /translation="NKDETTSYPTYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNQEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(507..1052)
                     /locus_tag="VVR08_002077"
     CDS             complement(507..1052)
                     /locus_tag="VVR08_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6075894.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          167 c          155 g          354 t
ORIGIN      
        1 gaataaagac gaaacaacct cttatcctac atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cttgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcaa gaagagatga aaagaatcat ttccaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgcttagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ttttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtatc aatgtagtaa
      901 tcgttatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattat taatgcttaa atcgcccttc ttgtaagaaa gacctgtatt cattgaaaaa
     1021 atatctttta tttttataac aacccaattc ataggt
//
LOCUS       DAVHSH010000111         1035 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000111 DAVHSH010000000
VERSION     DAVHSH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.112"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            480..>1035
                     /locus_tag="VVR08_002078"
     CDS             480..>1035
                     /locus_tag="VVR08_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6075895.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNH"
BASE COUNT          305 a          174 c          214 g          342 t
ORIGIN      
        1 taaattcttt gagctttttt ctttttaaat attgattgtt tctaaaagtt ctagtaatat
       61 tgctatttct catttttcca aatatgttat tcaacttatt agctacgtct ctattcatat
      121 ttgggtataa aacaaaaaat caattctaac agttttatat cagaataata aataaaaaag
      181 cgatattcta gactgtatca atccttttcc attataggag caacagagtg ggagtagtca
      241 tctaaggact aatttatgta tttttacgag tcagtatctt gggatactgg tttttacttt
      301 tttagacttt ttgactactt gttaaaactg gggtaatttt cgactgttta acagttatta
      361 tgcaaagtct aaaagattag aattgtcaaa acaatccgtc taggcttgat tttatccttt
      421 atttactata aaatgagaag gaaaaatgtc aaacttttat attgcaaata ggagaaatca
      481 tgacaaaaac attaaaacgt cctgaggttt tatcacctgc agggacttta gagaagctaa
      541 aggtagctgt tcagtatgga gcagatgctg tctttatcgg tggtcaggcc tatggtcttc
      601 gtagccgtgc gggaaacttt actttcgaac agatggaaga aggcgtgcag tttgcggcca
      661 agtatggtgc caaggtctat gtagcggcta atatggttat gcacgaagga aatgaagctg
      721 gtgctggtga gtggttccgt aaactgcgtg atatcgggat tgcagcagtt atcgtatctg
      781 acccagcctt gattatgatt gcagcgactg aagcaccagg ccttgaaatc cacctttcta
      841 cccaagccag tgccactaac tatgaaaccc ttgagttctg gaaagagcta ggcttgactc
      901 gtgtcgtttt agcgcgtgag gtttcaatgg aagaattagc tgagatccgc aaacgtacag
      961 atgttgaaat tgaagccttt gtccatggag ctatgtgtat ttcatactct ggacgttgta
     1021 ctctttcaaa ccaca
//
LOCUS       DAVHSH010000112         1032 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.113, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000112 DAVHSH010000000
VERSION     DAVHSH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.113"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(258..569)
                     /locus_tag="VVR08_002079"
     CDS             complement(258..569)
                     /locus_tag="VVR08_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075896.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(584..>1032)
                     /locus_tag="VVR08_002080"
     CDS             complement(584..>1032)
                     /locus_tag="VVR08_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU6075897.1"
                     /translation="EKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKI
                     PEYKFVAEVVSYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKI
                     DRAPNPMELLTIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT          320 a          198 c          177 g          337 t
ORIGIN      
        1 agacggattg ttttgacaat tctaaccttt tagactttgc ataataactg ttaaacagtc
       61 gaaaattacc ccagttttaa caagtagtca aaataccaga taaagtaaaa aggggctagg
      121 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
      181 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
      241 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
      301 aagcgagaaa aacaaaagag gcaacttaag ctttctttat attgcttata tgttaatagt
      361 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg ataaggctca
      421 aaagggtgat tttctaatga atcatgacac cgataacaag cataatactt tttacaatca
      481 tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct tgtttgctta
      541 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct cgaactgtga
      601 cgctggttcc atcttcctta taaaaattga tgagtccttc ttttaatgca cgaaccatgt
      661 ctcctgattg aacgggttgt gggactttaa tagtcaatag ttccattgga tttggagcgc
      721 ggtcgatttt atttcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
      781 aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt tgacgaatgg
      841 ttgctgtttg taccgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
      901 ttttacggcg agcaccaaac aactgctcat tttcagatgg tataccgtag tagaaacctg
      961 ttgccaattc acgttgggca accttccaca tctcgtccac caagtcttgt ttgatagctt
     1021 caaacttttc ag
//
LOCUS       DAVHSH010000113          961 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000113 DAVHSH010000000
VERSION     DAVHSH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.114"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            3..>961
                     /gene="phtA"
                     /locus_tag="VVR08_002081"
     CDS             3..>961
                     /gene="phtA"
                     /locus_tag="VVR08_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU6075898.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QAAQKTENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHRESGTPRNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRT"
BASE COUNT          337 a          193 c          194 g          237 t
ORIGIN      
        1 gaatgaaaat caataaaaaa tatctagctg ggtcagtagc tacacttgtt ttaagtgtct
       61 gtgcttatga actaggtttg catcaagctc aaactgtaaa agaaaataat cgtgtttcct
      121 atatagatgg taaacaagca gcacaaaaaa cggagaatct gactcctgat gaggtcagta
      181 aaaaagaagg tatcaatgcc gaacaaatcg tcatcaagat aacagaccaa ggctatgtca
      241 cttcacatgg cgaccactat cattattaca atggtaaggt tccttatgat gcgattttca
      301 gtgaagaatt actcatgaaa gatccaaact ataagctaaa agatgaggat attgttaatg
      361 aggtcaaggg tggatatgtt atcaaggtag atggaaaata ctatgtttac cttaaggatg
      421 ctgcccacgc ggataacgtc cgtacaaaag aggaaatcaa tcgacaaaaa caagaacata
      481 gtcaacatcg tgaaagtggg actccaagaa acgatggtgc ggtagccttt gcacgttcac
      541 agggacgcta caccacagat gatggttata tctttaatgc ttctgatatc attgaggaca
      601 cgggtgatgc ttatatcgtt cctcatggcg accattacca ttacattcct aagaatgagt
      661 tatcagctag cgagttagct gctgcagaag ccttcctatc tggtcgggga aatctgtcaa
      721 attcaagaac ctatcgccga caaaatagcg ataacacttc aagaacaaac tgggtacctt
      781 ctgtaagcaa tccaggaact acaaatacta acacaagcaa caacagcaac actaacagtc
      841 aagcaagtca aagtaatgac attgatagtc tcttgaaaca gctctacaaa ctgcctttga
      901 gtcaacgcca tgtagaatct gatggccttg ttttcgaccc agcgcaaatc acaagtcgaa
      961 c
//
LOCUS       DAVHSH010000114          745 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.115, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000114 DAVHSH010000000
VERSION     DAVHSH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.115"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..>745
                     /locus_tag="VVR08_002082"
     CDS             <1..>745
                     /locus_tag="VVR08_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075899.1"
                     /translation="IISFPEIEENLRKIVREKYLKRFNKESFDSNDRKFFEYHIKQQN
                     TDIDIFEKLLSINVNELSTPKGDNKQLDILHFINSEMGSYFQCLISLFINHSSYRDVI
                     IPIINSVTDTDYREFAQGILLNEYNPNRINVTYNTFLGFAYYHSTITIEAADVFTDVV
                     RNILNKKIEDNQILNKVYLVALERVDPTIESFSLSKNNYSQMINIIFTGDYEFRYSKE
                     WLGALFKFDSSANYLVTIFYLLYNENLKK"
BASE COUNT          304 a           83 c          103 g          255 t
ORIGIN      
        1 aaattatcag ttttcctgaa atagaagaaa atttgagaaa gattgttaga gaaaaatatt
       61 taaaaagatt taacaaagaa agttttgatt ctaacgatcg gaaattcttt gaatatcata
      121 taaaacaaca aaatacggat atagatattt ttgaaaaatt acttagtatc aatgtgaatg
      181 aactctcaac accaaaaggt gataataaac aattagatat acttcatttt ataaatagtg
      241 aaatgggatc atattttcaa tgtttaatat cattatttat aaatcattca agttatagag
      301 atgtaattat tccaataata aattcagtaa cagataccga ttatagggag tttgctcaag
      361 gtattttatt aaatgaatac aatccaaaca gaatcaatgt aacttacaac acctttttag
      421 gatttgcgta ttatcattct acaattacta tcgaagctgc ggatgttttc acagatgtag
      481 taaggaatat tctaaacaaa aaaattgagg acaatcaaat tcttaataaa gtttatctag
      541 ttgctttaga gagggtagat ccaactattg aatcattttc tttatcaaag aataactata
      601 gtcaaatgat aaacatcatt tttacaggag actatgaatt tagatattct aaagaatggt
      661 tgggagcatt attcaaattt gactcaagtg caaattattt ggtgacaatt ttttatttat
      721 tatataatga aaatcttaaa aaaaa
//
LOCUS       DAVHSH010000115          544 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.116, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000115 DAVHSH010000000
VERSION     DAVHSH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.116"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            153..>544
                     /locus_tag="VVR08_002083"
     CDS             153..>544
                     /locus_tag="VVR08_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075900.1"
                     /translation="MDLEFIKRLIDKIDFSNIHFGEELNTFIKEHRSIIREKNIEIPK
                     KPYRNWISSLEGGFVSQFSYLTQENLVEYDESRVLEILVNAEKEQRGSSFLEEKTINE
                     TENFFITVLKESNEISKKVSDLLKNHID"
BASE COUNT          225 a           48 c           87 g          184 t
ORIGIN      
        1 aagagtatga tgttgttaaa tttctttatg agcttgtaaa gtccaaaaaa ttatttattg
       61 aagaggaaaa gtttttagaa agtgattctg aagacttaat aagtactata ttaattcaaa
      121 aattgcttgt tcaattggat aatgaaatta atttggattt agaatttatc aagaggttaa
      181 ttgataaaat tgatttttca aatattcact ttggagagga attaaacact tttatcaaag
      241 aacatagaag tattattaga gaaaaaaata ttgaaatacc aaaaaaacct tatagaaatt
      301 ggatatcttc actagaagga ggttttgttt cacaattttc atatttaact caagaaaatc
      361 ttgtagagta cgatgaatct agagtattag agatattagt caacgccgaa aaggaacaaa
      421 gaggttcttc atttttggaa gaaaagacga taaatgaaac ggaaaatttc tttattactg
      481 ttttaaaaga atcaaatgaa atatctaaaa aagtttctga tttattgaaa aatcatatag
      541 atga
//
LOCUS       DAVHSH010000116          527 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.117, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000116 DAVHSH010000000
VERSION     DAVHSH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.117"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            1..527
                     /locus_tag="VVR08_002084"
                     /pseudo
     CDS             1..527
                     /locus_tag="VVR08_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          180 a           94 c           97 g          156 t
ORIGIN      
        1 atgggttaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag aaaaagtagc
       61 cttatttctt aagaatttta atagtttaaa gcacctagca cctgtttaga ttgacgaaac
      121 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaataag
      181 aggcaaagta tctggaagaa gatatcagag aatttctttg gttgcaggtc taacaaatga
      241 atggtgagtt aatcgctcca atgacttacg aagagacgat gacgagcgac ttttttgaag
      301 cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt attatggata
      361 atgcaagatt ccatagaatg ggtaagttag aactcttgtg tgaagagttt gggtataaac
      421 ttttacctct tcctccctac tcacctgagt acaatcctat tgagaaaaca tgggctcata
      481 tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac tttttat
//
LOCUS       DAVHSH010000117          525 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.118, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000117 DAVHSH010000000
VERSION     DAVHSH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.118"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(351..>525)
                     /locus_tag="VVR08_002085"
     CDS             complement(351..>525)
                     /locus_tag="VVR08_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU6075901.1"
                     /translation="SEELKNLGKWYVSTGKEWICHSDDDLEEFKNLFLNFINPEEWDT
                     ISFDSDFMPFQQS"
BASE COUNT          186 a           92 c           72 g          175 t
ORIGIN      
        1 gtttcagatt ctaaactaag tgattcaatc ctttttaagc tatctaaaca cattaaagtc
       61 atcaagcctt aataaactga aagagcctgg gtaacaactc aatttcagaa gaaaaaaagt
      121 aaatcttccc acaataaaaa gcatagtatc aggtgttgaa acacctgata ctatgctttt
      181 ttctatatca aagacttttt gcccaattcc tcaaagctat acattgagaa atctgcgact
      241 cgcttcctag tttaaagttg ctctttgatt ttcattgagt ataagcaacg tgattagata
      301 agagttttac agagtactaa atataagatt taactttttt gagaaattgg ttacgattgt
      361 tgaaacggca taaaatctga atcaaaggag atagtatccc attcttcagg attgataaaa
      421 tttaaaaata gatttttaaa ttcttccaga tcatcatctg aatgacaaat ccattcttta
      481 ccagtcgaga cataccattt tccaagattt ttcaattctt cactc
//
LOCUS       DAVHSH010000118          469 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.119, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000118 DAVHSH010000000
VERSION     DAVHSH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.119"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            1..402
                     /locus_tag="VVR08_002086"
                     /pseudo
     CDS             1..402
                     /locus_tag="VVR08_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          148 a           95 c           85 g          141 t
ORIGIN      
        1 gacatcatca ataaggatac acacaaggaa atcatcgcca aactggacta tgaagctcca
       61 tcttgtcctg agtgcggaaa ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt
      121 ccttatcttg aaacgactgg tatgcctact agaattctcc ttagaaagcg tcatttcaag
      181 tgctatcact gttctaaaat gatggtcgct gagacttcta tcgtcaagaa gaatcatcaa
      241 attccttgta tcatcaacca aaagattgat cagaagctaa ttgaaaagac ttctatgacc
      301 gacattgatc atcagttgtc tatttcaact tcaactgtca ttcgcaagat caatgatttt
      361 cactttgagc atgatttttc gcgtcttcct gagattatgt cctaggacgt tgaaacagtc
      421 tggggagtga ctgtttcaat cgggagatag agatgagctt tattgctca
//
LOCUS       DAVHSH010000119          407 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000119 DAVHSH010000000
VERSION     DAVHSH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.120"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..>407
                     /locus_tag="VVR08_002087"
     CDS             <1..>407
                     /locus_tag="VVR08_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HEU6075902.1"
                     /translation="SGKLATTVEVDGTKADAQKELELSVATDKVTKTVKDTVVYENLL
                     AGETYKLTGQLMKITADKEEEVATKETTFVADASGNGTTSLEFEDVSLEAGVKYVVYE
                     TAESEKEIDFKEGKEKHKVEHKDKDDKAQTVVVT"
BASE COUNT          160 a           68 c          101 g           78 t
ORIGIN      
        1 tcaggtaagc ttgcgacaac tgtagaagtt gacggaacaa aagctgatgc acagaaagag
       61 cttgagttgt cagttgcaac agataaagtt acgaagacag taaaagatac tgttgtgtac
      121 gaaaatctgt tagctggcga aacctacaaa ctaacaggtc agttgatgaa gattacagct
      181 gacaaagaag aggaagtagc aacgaaagaa acaaccttcg tcgcagatgc ctcaggcaac
      241 ggtacaacca gcctagagtt tgaagatgtg agccttgaag caggcgttaa gtatgtagta
      301 tatgaaactg cagagagcga aaaagaaatt gacttcaaag aaggcaaaga aaagcacaag
      361 gtagaacaca aagacaaaga tgacaaagct cagactgtag ttgttac
//
LOCUS       DAVHSH010000120          348 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.121, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000120 DAVHSH010000000
VERSION     DAVHSH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.121"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..153
                     /locus_tag="VVR08_002088"
     CDS             <1..153
                     /locus_tag="VVR08_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075903.1"
                     /translation="KIVNGLQLPYSNAKLEATNNLIKLIKYNAFGFRNFENFKKERTK
                     FVLSQA"
     gene            complement(272..345)
                     /locus_tag="VVR08_002089"
     tRNA            complement(272..345)
                     /locus_tag="VVR08_002089"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(309..311),aa:Asn,seq:gtt)
BASE COUNT          122 a           79 c           48 g           99 t
ORIGIN      
        1 aaaatcgtca acggccttca attaccttat tccaacgcca aactggaagc caccaataat
       61 ctcatcaaac ttatcaagta caatgccttt ggttttagga actttgaaaa cttcaaaaaa
      121 gaaaggacga aatttgtcct ttctcaagct tagcttttct tcaacccact acagttgaca
      181 aagagccact atttttggtt cattttacta taacacgaaa tagattatta ttacataata
      241 aaaaagaggt ctaaacctct taactaaatt actccgccag taggactcga acctacgaca
      301 tcatgattaa cagtcatgcg ctactaccaa ctgagctatg gcggatta
//
LOCUS       DAVHSH010000121          341 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.122, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000121 DAVHSH010000000
VERSION     DAVHSH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.122"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            15..>341
                     /locus_tag="VVR08_002090"
     CDS             15..>341
                     /locus_tag="VVR08_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6075904.1"
                     /translation="MHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKKDAHGIALKLLS
                     DPNREQFQHDNRQVELKILTRHIHRLKKKQSDWKVQYTRCLDIIFPELDKIVGKHSEY
                     TYQLLTR"
BASE COUNT          119 a           78 c           51 g           93 t
ORIGIN      
        1 atctactgaa cttcctgcat gaacaaggat ataaagttta cacctacact cctttgctca
       61 tcaaggaatt tgccaaatca ttatcacttc gcaagactaa aacggataag aaagacgctc
      121 atggcatcgc tcttaaactt ctttctgacc ccaatcgtga acaatttcaa cacgataatc
      181 ggcaagtaga actaaaaata ctgactagac atattcatcg tctcaagaaa aaacagtctg
      241 attggaaagt acaatacact cgttgtcttg atatcatctt tcctgagttg gataaaatcg
      301 ttggaaagca ttcagaatat acctaccaac tcttgacacg c
//
LOCUS       DAVHSH010000122          329 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.123, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000122 DAVHSH010000000
VERSION     DAVHSH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.123"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..>329
                     /locus_tag="VVR08_002091"
     CDS             <1..>329
                     /locus_tag="VVR08_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6075905.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKG
                     AEAIYNRV"
BASE COUNT          110 a           72 c           76 g           71 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgaaagag cggcagccca ggcttatgct
      241 aaagagaaag gtttgacccc tccttcgaca gaccatcagg attcaggaaa tactgaggca
      301 aaaggagcag aagctatcta caaccgcgt
//
LOCUS       DAVHSH010000123          286 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.124, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000123 DAVHSH010000000
VERSION     DAVHSH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.124"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..>286
                     /locus_tag="VVR08_002092"
     CDS             <1..>286
                     /locus_tag="VVR08_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075906.1"
                     /translation="MSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQP
                     APNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAG"
BASE COUNT           92 a           71 c           57 g           66 t
ORIGIN      
        1 atgtctgaat tggaaaaacg aattgctcgt attattcccc ttcgttatcg ttcaaaccat
       61 tgggtaccag attcaagacc agaacaacca agtccacaac cgactccaga acctagtcca
      121 agtccgcaac ctgcaccaaa tcctcaacca gctccaagca atccaattga tgagaaattg
      181 gtcaaagaag ctgttcgaaa agtaggcgat ggttatgtct ttgaggagaa tggagtttct
      241 cgttatatcc cagccaagga tctttcagca gaaacagcag caggca
//
LOCUS       DAVHSH010000124          238 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.126, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000124 DAVHSH010000000
VERSION     DAVHSH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.126"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..>238
                     /locus_tag="VVR08_002093"
     CDS             <1..>238
                     /locus_tag="VVR08_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6075907.1"
                     /translation="GGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAVDMSMID
                     HIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAA"
BASE COUNT           73 a           43 c           57 g           65 t
ORIGIN      
        1 tggtggatgt tctcagtcat gccgttggaa atacgacctt tacgatatgc catttgggaa
       61 agaacgtaag agtttgcagg gtgagattcc agaagaattt tcaatgtcag ccgttgacat
      121 gtctatgatt gaccacattc cagatatgat tgaaaatggt gtggacagtc taaaaatcga
      181 aggacgtatg aagtctattc actacgtatc aacagtaacc aactgctaca aggcggct
//
LOCUS       DAVHSH010000125          229 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.128, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000125 DAVHSH010000000
VERSION     DAVHSH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.128"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            complement(1..229)
                     /locus_tag="VVR08_002094"
                     /pseudo
     CDS             complement(1..229)
                     /locus_tag="VVR08_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT           66 a           31 c           54 g           78 t
ORIGIN      
        1 agtctgaaaa agaggtggaa aagcaagagc tgatagagat tatagtggtg tttcaagtct
       61 tcggaatagc tcaaaagttt atctagaatt tctttattag tcaagtgcat acgaaaagta
      121 gggcgataaa atcgtttatc actcagtttc tgactatctt gttgaatgag ctttcagtat
      181 cgcttgatag ccttgtattc atgggatttc ggatgatggc ttgtgttct
//
LOCUS       DAVHSH010000126          227 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.denovo.129, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000126 DAVHSH010000000
VERSION     DAVHSH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..227
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.denovo.129"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            <1..>227
                     /locus_tag="VVR08_002095"
     CDS             <1..>227
                     /locus_tag="VVR08_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075908.1"
                     /translation="TVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLAT
                     VKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           74 a           44 c           47 g           62 t
ORIGIN      
        1 actgtagaag tcaaaaacgg tagtttaatc atacctcatt atgaccatta ccataacatc
       61 aaatttgagt ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat
      121 cttttggcga ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcagataat
      181 ggttttggta acgctagcga ccatgttcaa agaaacaaaa atggtca
//
LOCUS       DAVHSH010000127        14051 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254709-rid19264863.guided.047, whole
            genome shotgun sequence.
ACCESSION   DAVHSH010000127 DAVHSH010000000
VERSION     DAVHSH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254709
            Sequence Read Archive: SRR2912554
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866619.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866619.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,060
            Genes (coding)                    :: 1,932
            CDSs (with protein)               :: 1,932
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 62 of 128
            Pseudo Genes (incomplete)         :: 53 of 128
            Pseudo Genes (internal stop)      :: 39 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254709-rid19264863.guided.047"
                     /strain="Streptococcus species"
                     /serotype="14"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-09-22"
                     /collected_by="Catrin Moore"
     gene            201..515
                     /locus_tag="VVR08_002096"
     CDS             201..515
                     /locus_tag="VVR08_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6075909.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            531..917
                     /locus_tag="VVR08_002097"
     CDS             531..917
                     /locus_tag="VVR08_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6075910.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            946..2331
                     /locus_tag="VVR08_002098"
     CDS             946..2331
                     /locus_tag="VVR08_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6075911.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2334..2486
                     /locus_tag="VVR08_002099"
     CDS             2334..2486
                     /locus_tag="VVR08_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6075912.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2509..3714
                     /locus_tag="VVR08_002100"
     CDS             2509..3714
                     /locus_tag="VVR08_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6075913.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            3757..3978
                     /locus_tag="VVR08_002101"
     CDS             3757..3978
                     /locus_tag="VVR08_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6075914.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4095..4592
                     /locus_tag="VVR08_002102"
     CDS             4095..4592
                     /locus_tag="VVR08_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6075915.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            4567..5073
                     /locus_tag="VVR08_002103"
     CDS             4567..5073
                     /locus_tag="VVR08_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6075916.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5057..7504
                     /locus_tag="VVR08_002104"
     CDS             5057..7504
                     /locus_tag="VVR08_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6075917.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7507..9684
                     /locus_tag="VVR08_002105"
     CDS             7507..9684
                     /locus_tag="VVR08_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6075918.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            9681..10682
                     /locus_tag="VVR08_002106"
     CDS             9681..10682
                     /locus_tag="VVR08_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6075919.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            10679..11614
                     /locus_tag="VVR08_002107"
     CDS             10679..11614
                     /locus_tag="VVR08_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6075920.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            11859..11975
                     /locus_tag="VVR08_002108"
     CDS             11859..11975
                     /locus_tag="VVR08_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6075921.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            11991..13910
                     /gene="tet(M)"
                     /locus_tag="VVR08_002109"
     CDS             11991..13910
                     /gene="tet(M)"
                     /locus_tag="VVR08_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6075922.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLETYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         4509 a         2565 c         2993 g         3984 t
ORIGIN      
        1 tggatataaa gatacttcca ataaaatttg aatatttaat aggtagacac ttcaaaaaat
       61 gaggtgtcta tttttttacc cgattttgaa aggaagtgaa cttatgaaaa caaaaaatca
      121 agaatcaaaa ggtcgttccc cactctttaa gaccatcaaa cattcattca gccaataaaa
      181 aagaaaggat aggtaaaaat atggaactta aatttgtgat tcccaacatg gaaaaaacat
      241 tcggcaattt agaatttgct ggcgaggata aagtcgttca gcgaagaatc aacggacggc
      301 taactgtctt atcaagaagc tataatctct attctgatgt tcaaagagca gatgatattg
      361 tggtggtgct tcctgctgaa gctggcgaaa aacatttcgg ctttgaggaa cgtgtgaagt
      421 tagtcaatcc acgtattacc gcagagggct acaaaatcgg cactcgtggt tttacaaatt
      481 accttttaca tgctgacgac atgataaaag aataaagaaa gagaggaaaa atgatgagat
      541 tagcaaatgg cattgtatta gataaagaca cgacttttgg agaattgaaa ttctctgctc
      601 tacgtcgtga agtgagaatc caaaatgaag acgggtcggt ttcagatgaa atcaaggaac
      661 gtacctatga cttaaaatcc aaaggacaag gacgcatgat tcaagtaagt attcctgcca
      721 gcgtgccttt gaaagagttt gattataacg cacgggtgga acttatcaat cccattgcgg
      781 acaccgttgc tactgccacc tatcaaggag cagatgttga ctggtatatc aaggcagacg
      841 atattgtgct gacaaaggat tctagttcat tcaaagctca accacaagca aagaaagaac
      901 cgacacaaga caaatagtcg ctaggtagaa aggagacttt ttcgcatgaa acagcgtggt
      961 aaaaggattc gcccatctgg taaagattta gtctttcatt ttacgatagc gtcactcctg
     1021 cctgttttcc tgctggttgt cggactgttt catgtgaaga caatccagca gatcaactgg
     1081 caggatttta acctatcaca agcagataag attgacattc cctatttaat tatcagtttc
     1141 agtgtcgcaa ttcttatctg cttgctggta gcgtttgtat tcaaacgggt tcgctatgat
     1201 acggttaaac aactttacca ccgtcaaaaa ctggcaaaga tgatacttga aaacaagtgg
     1261 tatgaatctg aacaggtcaa aacagagggt ttctttaaag atagtgctgg tcgtacaaag
     1321 gaaaagataa cctacttccc taaaatgtat tatcgactta aaaatggctt gatacagata
     1381 cgggtggaaa tcacgctggg aaaatatcaa gaccaactct tacacttgga aaagaaatta
     1441 gagagtggct tgtactgtga gctgacggat aaagagttaa aggattccta tgtggaatat
     1501 actttgctct atgacaccat agccagtcgt atttctattg atgaagtaga agctaaagat
     1561 ggtaaacttc gcttaatgaa aaacgtatgg tgggaatatg ataagctccc tcatatgttg
     1621 attgctggtg gtacaggtgg cggtaaaact tactttatac tgacactgat tgaagccttg
     1681 cttcatacag attcaaaact gtatattctt gacccgaaaa atgctgacct tgcggactta
     1741 ggttctgtga tggcaaatgt ctactataga aaagaagact tgctttcttg cattgaaaca
     1801 ttctatgaag aaatgatgaa acgtagtgag gaaatgaagc agatgaagaa ctataagact
     1861 ggcaaaaatt atgcttactt aggtctcccg gcacacttct taatctttga tgaatacgtc
     1921 gctttcatgg aaatgctggg aacaaaagaa aacaccgcag ttatgaataa gctgaaacag
     1981 attgtcatgt taggtcgtca agctggcttc tttctaatac tggcttgtca acgtccagac
     2041 gcaaaatatt taggcgacgg aatccgtgat cagtttaatt tcagagtggc tttaggtcgt
     2101 atgtctgaaa tgggctatgg catgatgttt ggcagtgacg tacaaaagga tttcttctta
     2161 aagcgaatca aaggtcgtgg ctatgttgat gtaggaacaa gtgtcatatc agagttttat
     2221 actccccttg taccaaaagg atatgatttc ttggaggaaa ttaaaaagtt atccaacagc
     2281 agacagtcca cgcaggcgac gtgcgaagcg gaagtcgcag gtgtggactg atcttgctgg
     2341 ctggtgtggc aatagccacg ccagcactta accccccgta tctaacaggg gggtacaaat
     2401 cgacaggaaa cagtcaaaaa aacattagaa aatcctttgg ttacaaggga tttacaaaat
     2461 ttcagcgtat gtcaaatggg ctttaaaagt tgacatacgc ctttttgatt ggagggattt
     2521 ttactgaatg aacaaacttg gttacagcat ttaaaagaaa aacgcttggc ttatggacta
     2581 tctcaaaacc gtttagctgt tgcgactggt attacaaggc agtatctaag cgatattgaa
     2641 acaggaaaag tcaagccatc agaggattta cagcagtccc tttgggaagc tctggaacgc
     2701 ttcaatcccg acgctcccct tgaaatgctg tttgattatg taaggattcg ctttccgaca
     2761 acagacgtac agcaggtggt cgaaaacatc ttacaactga aactgtccta ttttcttcat
     2821 gaggactatg gtttctattc ttattcagag cattatgctt taggcgacat attcgtcctt
     2881 tgctcccatg aactggacaa aggagttctg gtggaattga aaggtcgtgg gtgcagacaa
     2941 tttgaaagct atcttctggc acaacaaaga agctggtatg agttctttat ggacgttttg
     3001 gtggctggcg gtgtgatgaa acgccttgac cttgccatta acgataagac agggattttg
     3061 aatatccctg tactcactga aaagtgccaa caggaagaat gtatctccgt cttccgcagt
     3121 tttaaaagct atcgcagtgg cgaactggta cgcaaagagg aaaaggaatg tatgggaaac
     3181 accctctata tcggttcatt acaaagtgaa gtttatttct gtatctatga aaaggactac
     3241 gagcagtaca agaaaaatga tattcccatt gaagacgcag aagtaaaaaa ccgttttgag
     3301 attcgattga aaaatgagcg tgcctattat gcagtccgtg atttactcgt ctatgacaat
     3361 ccagagcata ccgcctttaa aattatcaat cggtatatcc gttttgtaga taaagacgat
     3421 tccaaacctc gttctgattg gaaactgaat gaagaatggg cttggtttat tgggaacaat
     3481 cgtgaacgat taaaactaac cacaaaacca gagccttact ccttccaaag gacgctgaac
     3541 tggctatctc atcaagttgc cccgacctta aaggttgcga ttaaacttga tgaaatcaac
     3601 cagacgcagg ttgtaaaaga cattctcgac catgcgaaac tgacagaccg acacaagcag
     3661 attttgaagc aacagtcagt aaaagaacag gacgtgataa caacaaaaaa ataactcaaa
     3721 tacaaattca ttgaatatag agaggagaac atttttatga attttggaca aaacctttat
     3781 aactggtttc tatcaaacgc tcaatcactg gtgcttttag caatcgttgt gattggcttg
     3841 tatcttggct tcaagcgtga gtttagcaaa ctgattggct ttttaattat tgcgattatt
     3901 gcggttggct tagtcttcaa cgctgctgga gtaaaagaca ttttactaga gctattcaat
     3961 cgcattattg gtgcttaaat aaaaccgttc ttttgtggaa tataagtggt tttcttatgt
     4021 tccgcaaagg aatggtacac caaacgaagt gcggtaggga tttttgaatc tctacaaaga
     4081 aaggacgtga atatatggac gatatgcaag tctatattgc gaatttaggc aaatacaatg
     4141 agggcgaatt ggtcggtgcg tggtttacct ttcccattga ctttgaggaa gtcaaagaga
     4201 aaatcggctt gaatgatgaa tatgaggaat acgccattca tgactacgag ttacccttta
     4261 cggttgacga atacacttcc attggcgaac tcaatcgact atgggaaatg gtatcggaat
     4321 tacccgaaga attacaatcg gagctatctg ctctgctcac tcatttttca agcattgaag
     4381 aactaagcga acatcaagag gatattatca ttcattccga ttgtgatgat atgtatgacg
     4441 tggcacgcta ctacattgaa gaaacgggtg ctttaggcga agtaccagct agtcttcaaa
     4501 actatattga ttatcaagcc tatggtcggg atttagacct ttcaggaacg tttatctcaa
     4561 ccaatcatgg gatttttgaa atcgtctatt aaatctgtcg gtacattact actggcagat
     4621 tttctatttt acggggtggc tcaatcagct acccctattt tttatgaaag gattgattac
     4681 atgaagaaaa tacgaagcta taccagtatc tggtctgtgg aaaaggtact gtattctatc
     4741 aatgatttta gacttccgtt tcccataacc tttacgcaaa tgacatggtt tgtcgtgtca
     4801 ctctttgcag tgatgatact tggcaacttg ccccctcttt ccatgataga gggagcattt
     4861 ctcaaatact ttgggattcc tgtggctttc acatggttta tgtctacaaa aacttttgat
     4921 ggtaaaaagc cttatggatt tttgaagtct gtcattgctt atgcactgcg accaaagctg
     4981 acctatgcag gaaaaaaagt aacgcttggc agaaaccagc cacaagaagc cattacagca
     5041 gttaggagtg aattttatgg catatccaat taaatacatt gaaaacaatc tcgtctggaa
     5101 taaagacggg gaatgttatg cttactatga gcttgttcct tacaattact catttctaag
     5161 tccagaacag aaaatacaag tgcatgattc tttcagacag cttatcgcac aaaatcgtga
     5221 tggcaaaatt catgctttac aaatcagtac agaatccagc atacgttctg cacaagagcg
     5281 ttccaaaaat gaagtcactg gcaagctcaa agcggttgcc tatgacaaaa tcgaccaaca
     5341 gacagacgct ttaatatcca tgattggcga aaatcaagtg aactaccgtt tctttatcgg
     5401 ctttaagttg cttctcaacg atcaggagtt ttctatgaaa agtcttaccg ttgaagcaaa
     5461 aaatgctttg tctgattttg tctatgatgt gaaccataag ctgatgggcg attttgttag
     5521 tatgagtaat gatgaaatcc tgcgttttca gaagatggaa aagctcttag aaaataaaat
     5581 ctctcgtcgt ttcaaaatcc gcaggttaga taaggacgac ttcggctatc tgattgaaca
     5641 cctttacgga cagacaggca ctgcctatga agagtatgag taccatctat caaagaaaaa
     5701 gctggataat gaaacgctga ttaaatacta tgacttgatt aagcctactc gctgtttggt
     5761 ggaagaaaaa cagcgatatt tgaaaatcca gcaggaagat gaaaccgtct atgtagctta
     5821 ctttaccatt aacagcattg tcggagaact ggacttcccg tcctctgaaa tcttctacta
     5881 ccagcaacag caatttacat tcccgattga tacgtcaatg aatgtggaaa ttgtagcgaa
     5941 tcgtaaagcc ctatctactg tccgcaataa aaagaaagaa ctgaaagact tggataacca
     6001 cgcttggcaa agtgataatg aaaccagctc caatgtggcg gaagctctgg aaagtgtgaa
     6061 tgagctggaa accaatttag accaaagcaa ggaatctatg tacaagctgt cttatgtggt
     6121 aagggtatca gcaaatgatc ttgacgaact caaacgtcgt tgtaatgaag tgaaagattt
     6181 ttatgacgat ttaagcgtaa aactggtacg accatttggg gatatgctcg gcttacatga
     6241 agaattttta cctgccagca agcgttatat gaatgattat attcaatacg tgacctctga
     6301 tttcctcgct ggtttaggtt ttggtgctac tcaaatgctg ggggaaaatg aggggattta
     6361 tgttggctac agcttagata ctggacgcaa tgtctatctg aaacctgctc ttgccagtca
     6421 aggggttaag ggttcagtaa ccaatgcgtt agcgtcggct tttgttggtt cgctgggtgg
     6481 tggtaaatcc tttgcgaata accttatcgt ctattatgcg gtgctttatg gggcacaagc
     6541 agtgattgta gacccaaaag cagaacgtgg cagatggaaa gaaaccttgc cagagatttc
     6601 ccatgaaatc aatatcgtca ctctgacttc tgatgagaaa aacaaaggct tacttgaccc
     6661 ttatgtgatt atgaaaaatc ccaaagattc tgaatcactg gctattgata ttctgacatt
     6721 ccttacgggg atttcctctc gtgatgggga acgcttccca atccttagaa aagccattcg
     6781 tgcagtaacc aatagtgaag tacgagggtt gatgaaagtg attgaggaat tacgggttga
     6841 gaatacgcca ctaagtacca gtatagccga ccatatcgaa agttttacag actatgactt
     6901 tgcacattta ttattcagta atggttatgt ggagcagtct atcagcttag aaaaacaact
     6961 gaacattata caggttgcgg acttggtact tcccgacaag gaaacttcct ttgaggaata
     7021 taccactatg gagcttttat ccgttgctat gctgattgtc attagtacct ttgctttaga
     7081 ctttatccat acagaccgaa gcattttcaa gattgtagat ttagacgaag catggagctt
     7141 tttacaggta gcacaaggaa aaacactatc tatgaagctg gttcgggctg gtcgtgctat
     7201 gaacgctggg gtatatttcg tgacccaaaa tacagacgac ctcttagatg aaaaactgaa
     7261 aaataacctc ggcttaaaat ttgcatttcg ttccactgac cttaacgaga ttaaaaagac
     7321 cttagccttt tttggtgtag acccagagga cgaaaacaat cagaagcgat tgcgtgattt
     7381 ggaaaacggg caatgcctta tcagtgattt atatggtcgt gtcggtgtga tacagttcca
     7441 ccctgtattt gaagaactgc tccatgcctt tgataccaga ccacctgtgc gaaaagaggt
     7501 gtaaatgtga aaccatcaat agtaaacaga ataaaatcaa actggacgct gaaacgtcta
     7561 ggtaaagtgg caatgacagt ggctttcaca cttgtgattg ccatttttct tttagccatg
     7621 ctgggaacgg tggttcaagc tgcgggcttg gtagatgata cggtcaatgt ggcaaatgaa
     7681 tacagccgat acccacttga aaactatcaa ctggattttt atgtggataa tagctggggc
     7741 tggcttccgt ggaactggtc ggacgggatt ggaaaacagg tcatgtatgg actatatgcc
     7801 attaccaatt ttatttggac aatcagtttg tatgtttcca atgcgacagg ttacttagta
     7861 caggaagcct attccttaga cttcatttcc gctacagcag attccattgg taagaatatg
     7921 cagaccttag ctggtgtgag tgcaaacgga ttttcaacag agggtttcta tgttggattc
     7981 ctcttactct tgattttggt tcttggggtt tatgttgcct atacgggact gataaagaga
     8041 gaaaccacaa aggcaattca tgccattatg aattttgtgc tggtgtttat cctatcggct
     8101 tcctttattg cctacgctcc cgactacatt aaaaaaatca atgacttttc atcagacatc
     8161 agtaatgcca gtttatcact tggcacgaag attgtcatgc cccattccga tagtcaaggc
     8221 aaggacagcg tggacttaat cagagatagc ctgttttcca tacaggttca gcaaccgtgg
     8281 ctactgcttc aatacaacag ttcagacatt gaaagtatcg gtattgaccg tgtggaaagc
     8341 ctgctctcca ccagcccaga ttccaacaat ggcgaagaca gagaaaaaat tgttgcggaa
     8401 gaaattgaag acagaagcaa taccaatcta accattacaa agaccattaa ccgtttaggt
     8461 acagtcttct tcctatttgt cttcaatatt gggatttcca tatttgtatt cctattaaca
     8521 ggaatcatga ttttctcgca ggtacttttt atcatctatg ctatgtttct gcctgtgagc
     8581 tttattttaa gcatgattcc atcatttgat ggtatgtcaa aacgagccat aacaaagctc
     8641 tttaatacca ttttgacacg agctggaatc acattgatta ttacgacagc atttagtatt
     8701 tcaaccatgc tctatacctt atcggctggt tatccgttct ttttgattgc ttttctacag
     8761 attgtgacct ttgcaggaat ctacttcaag ctgggcgatt taatgagtat gttttctcta
     8821 cagagtaacg attctcaaag tgtgggaagt cgtgtgatga gaaaacctcg tatgcttatg
     8881 cacgctcaca tgcaccgtct acagcggaaa cttggacgtt ccatgactac tctaggggct
     8941 gggtctgcca ttgttacagg taaaaaagga cagtcgggtt cggggagttc tgcaaggaca
     9001 caagcagatc actcccgacc agacggaaag gaaaaatcaa cacttggaaa acgtatcggt
     9061 caaaccatcg gtacagtagc tgataccaaa gacagaatgg tagacactgc tagtggtttg
     9121 aaagaacagg ttaaagattt gccgaccaat gcaagatatg cagtatatca aggaaaatcc
     9181 aaagtaaaag agaatgtccg tgatttaacc agtagtattt ctcaaaccaa agcggacaga
     9241 gccagtggac gcaaggaaca gcaggaacaa aggcgaaaaa ccattgcgaa gcgtcgctct
     9301 gaaatggaac aggtcaaaca gaaaaaacag cctgcttctt ctgttcatga aagaccgact
     9361 acaagacaag aacaatatca tgatgaacag acctcaaaac agtctaatat tcagacttca
     9421 tataaggaat ctcaacaagc caaacaagag cgtccagcag ttaagtccga tttttcaagt
     9481 ccaaaagtgg aacgccaagg caataccgtt caagaaaaaa ccgttcaaaa gccagcaact
     9541 tcaaccacta cagcagatag aacttcacaa cgtccaatca caaaagaacg tccgtctact
     9601 gttcaaagag taccactaca aaatacaaga agtagaccac caatcaaaac cgccaccatt
     9661 aagaaagtcg gtaagaaacc atgaagttga aaactttagt gattggtggt tctggattat
     9721 tcttgatggt cttctcactg cttctgtttg ttgccatttt attttcagat gaacaggaca
     9781 gcggaatttc caatattcat tatggaggtg tgaatgtttc cgcagaagtg ctggctcata
     9841 agcctatggt agaaaaatat gccaaagaat atggcgttga agaatatgtc aacatacttc
     9901 ttgcgattat acaggtggaa tcgggcggta ctgcggaaga tgttatgcag tcctcggaat
     9961 ccctcggtct tccacctaat tcattgagta cagaagaatc cattaagcaa ggtgtgaagt
    10021 atttcagtga attattagcc agtagcgaaa ggctcagtgt agatttagaa tcggttatcc
    10081 agtcctacaa ttatggtggt ggtttcttag ggtatgtggc taatcgtgga aataaatata
    10141 cctttgaact ggctcaaagt ttctcaaaag agtattcagg tggcgaaaaa gtgtcttacc
    10201 ccaatcccat agccatacct atcaatgggg gctggcgata caactatggc aatatgtttt
    10261 atgtgcaact ggtaacgcag tatcttgtca caacagagtt tgatgatgat acggtacaag
    10321 ccatcatgga cgaagcactg aaatatgagg gctggcgata cgtttacggt ggagcttccc
    10381 cgactacttc ttttgattgt agcggactga cacaatggac gtatggaaaa gctggaatta
    10441 acttaccacg aaccgcacaa cagcaatatg atgtgaccca gcatatccca ctatcggaag
    10501 cacaagctgg cgatttggtt ttctttcatt ctacctataa cgctggctct tatattactc
    10561 atgttgggat ataccttggc aataaccgta tgtttcatgc aggcgaccca atcggttatg
    10621 ccgacttaac aagcccctac tggcaacagc atttagtggg agcaggacga atcaaacaat
    10681 gagaaaggaa gatttaatga tgaaatttag aaaaaatcag aataaagaaa aacagatacc
    10741 aaaggaaaag aaacctcgtg tctactataa ggtcaatcct cataaaaagg ttgtgattgc
    10801 cttgtgggta cttttagggc ttagtttcag ctttgcgata ttcaagcact ttacagctat
    10861 agatactcat actattcacg aaacaactat catagaaaag gaatacgttg atactcatca
    10921 tgtagaaaat tttgtagaga actttgcgaa agtctactat tcatgggagc aatccgataa
    10981 gtccattgat aatcgaatgg aaagtctaaa aggctatctg acagatgaac ttcaagctct
    11041 caatgttgat acagtacgca aagatattcc tgtatcgtct tctgtaagag gatttcagat
    11101 atggacggta gagccaactg gcgacaatga gtttaatgta acctacagtg tagaccagct
    11161 cattacagag ggagaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt
    11221 agatggttct ggaaatatgg tactggttaa gaatccgacc attaccaaca tacctaagaa
    11281 atcaagttat aaaccaaaag ccattgaaag tgaggggacg gttgattcca ttacaaccaa
    11341 tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga
    11401 actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca
    11461 agaactggta aatcctattc acaatcgtaa ggataatcaa gtcacggtat cgctgacagt
    11521 ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga
    11581 aaagaacggg agtaattgga agattataga ataacaaata ttggtacatt attacagcta
    11641 ttttgtaatc acgtactctc tttgataaaa aattggagat tccttgacaa atatgctctt
    11701 acgtgctatt atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct
    11761 taaataaact gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc
    11821 ttagtttttt gtacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga
    11881 atatctgtat gctttgtatg cctatggtta tgcataaaaa tcccagtgat aaaagtattt
    11941 atcactggga tttttatgcc cttttgggtt tttgaatgga ggaaaatcac atgaaaatta
    12001 ttaatattgg agttttagct catgttgatg caggaaaaac taccttaaca gaaagcttat
    12061 tatataacag tggagcgatt acagaattag gaagcgtgga caaaggtaca acgaggacgg
    12121 ataatacgct tttagaacgt cagagaggaa ttacaattca gacaggaata acctcttttc
    12181 agtgggaaaa tacgaaggtg aacatcatag acacgccagg acatatggat ttcttagcag
    12241 aagtatatcg ttcattatca gttttagatg gggcaattct actgatttct gcaaaagatg
    12301 gcgtacaagc acaaactcgt atattatttc atgcacttag gaaaatgggg attcccacaa
    12361 tcttttttat caataagatt gaccaaaatg gaattgattt atcaacggtt tatcaggata
    12421 ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa ggtagaactg tatcctaata
    12481 tgtgtgtgac gaactttacc gaatctgaac aatgggatac ggtaatagag ggaaacgatg
    12541 accttttaga gaaatatatg tccggtaaat cattagaagc attggaactc gaacaagagg
    12601 aaagcataag atttcagaat tgttctctgt tccctgttta tcacggaagt gcaaaaaaca
    12661 atatagggat tgataacctt atagaagtga ttacgaataa attttattca tcaacacatc
    12721 gaggtcagtc tgaactttgc ggaaaagttt tcaaaattga gtattcggaa aaaagacagc
    12781 gtcttgcata tatacgtctt tatagtggcg tactgcattt gcgagattcg gttagaatat
    12841 cggaaaagga aaaaataaaa attacagaaa tgtatacttc aataaatggt gaattatgta
    12901 aaattgataa ggcttattcc ggggaaattg ttattttgca gaatgagttt ttgaagttaa
    12961 atagtgttct tggagataca aagctattgc cacagagaga gagaattgaa aatcccctcc
    13021 ctctgctgca aacgactgtt gaaccgagca aacctcaaca aagggaaatg ttacttgatg
    13081 cacttttaga aatctccgac agtgacccgc ttctgcgata ttatgtggat tctgcgacac
    13141 atgaaatcat actttctttc ttagggaaag tacaaatgga agtgacttgt gctctgctgc
    13201 aagaaaagta tcatgtggag atagaaataa aagagcctac agtcatttat atggaaagac
    13261 cgttaaaaaa agcagagtat accattcaca tcgaagttcc accgaatcct ttctgggctt
    13321 ccattggtct atctgtagca cagcttccat tagggagcgg agtacagtat gagagctcgg
    13381 tttctcttgg atacttaaat caatcgtttc aaaatgcagt tatggagggg atacgctatg
    13441 gctgtgaaca aggattgtat ggttggaatg tgacggactg taaaatctgt tttaagtatg
    13501 gcttatacta tagccctgtt agtaccccag cagattttcg gatgcttgct cctattgtat
    13561 tggaacaagt cttaaaaaaa gctggaacag aattgttaga gacatatctt agttttaaaa
    13621 tttatgcgcc acaggaatat ctttcacgag catacaacga tgctcctaaa tattgtgcga
    13681 acatcgtaga cactcaattg aaaaataatg aggtcattct tagtggagaa atccctgctc
    13741 ggtgtattca agaatatcgt agtgatttaa ctttctttac aaatggacgt agtgtttgtt
    13801 taacagagtt aaaagggtac catgttacta ccggtgaacc tgtttgccag ccccgtcgtc
    13861 caaatagtcg gatagataaa gtacgatata tgttcaataa aataacttag tgtattttat
    13921 gttgttatat aaatatggtt tcttgttaaa taagatgaaa tattctttaa taaagatttg
    13981 aattaaagtg taaaggagga gatagttatt ataaataaga ggcatatacc aattagaatt
    14041 cggaatacta t
//
